Lsm11 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lsm11
Entrez Gene ID	501688
Full Name	LSM11, U7 small nuclear RNA associated
Synonyms	RGD1565523
General protein information	Preferred Names LSM11, U7 small nuclear RNA associated Names U7 snRNA-associated Sm-like protein LSm11 U7 snRNP-specific Sm-like protein LSM11
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q21

mRNA and Protein(s)

mRNA	Protein	Name
NM_001173384.1	NP_001166855.1	U7 snRNA-associated Sm-like protein LSm11
XM_006246151.3	XP_006246213.1	U7 snRNA-associated Sm-like protein LSm11 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LSM11	XP_001138531.1
Rattus norvegicus (Norway rat)	Lsm11	NP_001166855.1
Xenopus tropicalis (tropical clawed frog)	lsm11	XP_002939655.2
Homo sapiens (human)	LSM11	NP_775762.1
	LOC100429445	XP_002804651.1
Mus musculus (house mouse)	Lsm11	NP_082461.1
Gallus gallus (chicken)	LSM11	XP_414562.3
Bos taurus (cattle)	LSM11	XP_002707877.1

Gene Ontology
Bibliography

Related articles in PubMed

Three proteins of the U7-specific Sm ring function as the molecular ruler to determine the site of 3'-end processing in mammalian histone pre-mRNA.
Yang XC, Torres MP, Marzluff WF, Dominski Z
Molecular and cellular biology29(15)4045-56(2009 Aug)

Purification of human telomerase complexes identifies factors involved in telomerase biogenesis and telomere length regulation.
Fu D, Collins K
Molecular cell28(5)773-85(2007 Dec)

ZFP100, a component of the active U7 snRNP limiting for histone pre-mRNA processing, is required for entry into S phase.
Wagner EJ, Marzluff WF
Molecular and cellular biology26(17)6702-12(2006 Sep)

Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing.
Pillai RS, Grimmler M, Meister G, Will CL, L?hrmann R, Fischer U, Sch?mperli D
Genes & development17(18)2321-33(2003 Sep)

Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein.
Pillai RS, Will CL, L?hrmann R, Sch?mperli D, M?ller B
The EMBO journal20(19)5470-9(2001 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Lsm11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lsm11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06510	NM_001173384.1 Latest version!	Rattus norvegicus LSM11, U7 small nuclear RNA associated (Lsm11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
ORa32979	XM_006246151.3 Latest version!	Rattus norvegicus LSM11, U7 small nuclear RNA associated (Lsm11), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lsm11 ( NM_001173384.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001166855.1 Rattus norvegicus LSM11, U7 small nuclear RNA associated (Lsm11), mRNA.

Price & Availability↑

CloneID	ORa06510
Clone ID Related Accession (Same CDS sequence)	NM_001173384.1
Accession Version	NM_001173384.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1083bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-28
Organism	Rattus norvegicus(Norway rat)
Product	U7 snRNA-associated Sm-like protein LSm11
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC158836.1. On or before May 13, 2010 this sequence version replaced XM_577085.3, XM_001068848.2. ##Evidence-Data-START## Transcript exon combination :: BC158836.1, FQ223124.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906351 [ECO:0000348] ##Evidence-Data-END##

ATGGAGGAGC GCGAGTGGGG GGCGAGGTCG GCTCGCGCCG GCAGCCCAGC CAGCCCGCCC 
AGCCCGCGGC TGGACGTCAG CTCCTACAGC TTCGACCCGC TGCTGGCCCT GTACGCGCCG 
CGCCTGCCGC CCATTCCTTA CCCCAACGCT CCCTGCTTCA ACAACGTGGC GGAGTACGAG 
AGCTTCCTGA AGGGCGGGCG CACCGGGCGC GGTCGAGCTC GGGGCACGGG AGAGCCGGCC 
TCGGCGGGAA CCTCCACCGG AACCTCCACG GGAGCCGGGA CCTCGTCCAG GGCCCGTCGC 
CGAGCCGCGC CCACCCCGGA TCCCGAGCGC ATCCAGCGCC TGCGCCGGCT CATGGTGGTC 
AAGGAGGACA CGGACGGCAC GGCCGGGTCG CGACGCCAGG GCCCGGGGCG CAGCAAGAAG 
GCACCCCGCA ACGTGCTCAC GCGGATGCCC TTGCATGAGG GTAGCCCTCT GGGCGAGCTG 
CACCGCTGCA TCCGAGAGGG GGTGAAGGTG AACGTGCACA TCCGCACTTT CAAGGGACTC 
CGCGGCGTCT GCACTGGCTT CCTCGTTGCC TTCGACAAGT TCTGGAACAT GGCCCTCACA 
GACGTGGATG AGACCTACCG TAAACCTGTC TTAGGCAAAG CATACGAACG GGATTCTTCG 
CTGACTCTCA CTAGGCTATT TGATCGGCTG AAACTCCAAG ATTCCAAAAA GGAAGCGGAT 
TCCAAGTCTG CAGTGGAGGA CTCCACCCTG TCTCGTTACT CCCAGACATC TACTTGGAAG 
GTGGCTTCAG TGTGGGGACG AGGAGACACT GACCGAGGCT CACACAGGCG CTCCCGCTCC 
GTCCCTTCTT CCCTGCAGGC ATCTGCAAGG GAGGAGTCCA GGTCTGAGCT GTCAGGGAGG 
ACTACACGGA CAGAAGGGTC CAGTGTGGGA GGTACCTTCT CCAGGGCCAC CACCCTTTCA 
CGGGGCCAGT CCCGTAAGAA AAAGCGAAAG CCCAAGGTGG ATTACCAGCA AGTGTTTACT 
CGACACATAA ATCAGATTTT CATTCGAGGT GAGAATGTCC TGCTGGTTCA TCTTGCACAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001166855.1
CDS	8..1090
Translation	MEEREWGARSARAGSPASPPSPRLDVSSYSFDPLLALYAPRLPPIPYPNAPCFNNVAEYESFLKGGRTGRGRARGTGEPASAGTSTGTSTGAGTSSRARRRAAPTPDPERIQRLRRLMVVKEDTDGTAGSRRQGPGRSKKAPRNVLTRMPLHEGSPLGELHRCIREGVKVNVHIRTFKGLRGVCTGFLVAFDKFWNMALTDVDETYRKPVLGKAYERDSSLTLTRLFDRLKLQDSKKEADSKSAVEDSTLSRYSQTSTWKVASVWGRGDTDRGSHRRSRSVPSSLQASAREESRSELSGRTTRTEGSSVGGTFSRATTLSRGQSRKKKRKPKVDYQQVFTRHINQIFIRGENVLLVHLAQ

Target ORF information:

RefSeq Version	NM_001173384.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus LSM11, U7 small nuclear RNA associated (Lsm11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001173384.1

ORF Insert Sequence:

ATGGAGGAGC GCGAGTGGGG GGCGAGGTCG GCTCGCGCCG GCAGCCCAGC CAGCCCGCCC 
AGCCCGCGGC TGGACGTCAG CTCCTACAGC TTCGACCCGC TGCTGGCCCT GTACGCGCCG 
CGCCTGCCGC CCATTCCTTA CCCCAACGCT CCCTGCTTCA ACAACGTGGC GGAGTACGAG 
AGCTTCCTGA AGGGCGGGCG CACCGGGCGC GGTCGAGCTC GGGGCACGGG AGAGCCGGCC 
TCGGCGGGAA CCTCCACCGG AACCTCCACG GGAGCCGGGA CCTCGTCCAG GGCCCGTCGC 
CGAGCCGCGC CCACCCCGGA TCCCGAGCGC ATCCAGCGCC TGCGCCGGCT CATGGTGGTC 
AAGGAGGACA CGGACGGCAC GGCCGGGTCG CGACGCCAGG GCCCGGGGCG CAGCAAGAAG 
GCACCCCGCA ACGTGCTCAC GCGGATGCCC TTGCATGAGG GTAGCCCTCT GGGCGAGCTG 
CACCGCTGCA TCCGAGAGGG GGTGAAGGTG AACGTGCACA TCCGCACTTT CAAGGGACTC 
CGCGGCGTCT GCACTGGCTT CCTCGTTGCC TTCGACAAGT TCTGGAACAT GGCCCTCACA 
GACGTGGATG AGACCTACCG TAAACCTGTC TTAGGCAAAG CATACGAACG GGATTCTTCG 
CTGACTCTCA CTAGGCTATT TGATCGGCTG AAACTCCAAG ATTCCAAAAA GGAAGCGGAT 
TCCAAGTCTG CAGTGGAGGA CTCCACCCTG TCTCGTTACT CCCAGACATC TACTTGGAAG 
GTGGCTTCAG TGTGGGGACG AGGAGACACT GACCGAGGCT CACACAGGCG CTCCCGCTCC 
GTCCCTTCTT CCCTGCAGGC ATCTGCAAGG GAGGAGTCCA GGTCTGAGCT GTCAGGGAGG 
ACTACACGGA CAGAAGGGTC CAGTGTGGGA GGTACCTTCT CCAGGGCCAC CACCCTTTCA 
CGGGGCCAGT CCCGTAAGAA AAAGCGAAAG CCCAAGGTGG ATTACCAGCA AGTGTTTACT 
CGACACATAA ATCAGATTTT CATTCGAGGT GAGAATGTCC TGCTGGTTCA TCTTGCACAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lsm11 ( XM_006246151.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006246213.1 Rattus norvegicus LSM11, U7 small nuclear RNA associated (Lsm11), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa32979
Clone ID Related Accession (Same CDS sequence)	XM_006246151.3
Accession Version	XM_006246151.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 999bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	U7 snRNA-associated Sm-like protein LSm11 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006246151.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGAGC GCGAGTGGGG GGCGAGGTCG GCTCGCGCCG GCAGCCCAGC CAGCCCGCCC 
AGCCCGCGGC TGGACGTCAG CTCCTACAGC TTCGACCCGC TGCTGGCCCT GTACGCGCCG 
CGCCTGCCGC CCATTCCTTA CCCCAACGCT CCCTGCTTCA ACAACGTGGC GGAGTACGAG 
AGCTTCCTGA AGGGCGGGCG CACCGGGCGC GGTCGAGCTC GGGGCACGGG AGAGCCGGCC 
TCGGCGGGAA CCTCCACCGG AACCTCCACG GGAGCCGGGA CCTCGTCCAG GGCCCGTCGC 
CGAGCCGCGC CCACCCCGGA TCCCGAGCGC ATCCAGCGCC TGCGCCGGCT CATGGTGGTC 
AAGGAGGACA CGGACGGCAC GGCCGGGTCG CGACGCCAGG GCCCGGGGCG CAGCAAGAAG 
GCACCCCGCA ACGTGCTCAC GCGGATGCCC TTGCATGAGG GTAGCCCTCT GGGCGAGCTG 
CACCGCTGCA TCCGAGAGGG GGTGAAGGTG AACGTGCACA TCCGCACTTT CAAGGGACTC 
CGCGGCGTCT GCACTGGCTT CCTCGTTGCC TTCGACAAGT TCTGGAACAT GCTATTTGAT 
CGGCTGAAAC TCCAAGATTC CAAAAAGGAA GCGGATTCCA AGTCTGCAGT GGAGGACTCC 
ACCCTGTCTC GTTACTCCCA GACATCTACT TGGAAGGTGG CTTCAGTGTG GGGACGAGGA 
GACACTGACC GAGGCTCACA CAGGCGCTCC CGCTCCGTCC CTTCTTCCCT GCAGGCATCT 
GCAAGGGAGG AGTCCAGGTC TGAGCTGTCA GGGAGGACTA CACGGACAGA AGGGTCCAGT 
GTGGGAGGTA CCTTCTCCAG GGCCACCACC CTTTCACGGG GCCAGTCCCG TAAGAAAAAG 
CGAAAGCCCA AGGTGGATTA CCAGCAAGTG TTTACTCGAC ACATAAATCA GATTTTCATT 
CGAGGTGAGA ATGTCCTGCT GGTTCATCTT GCACAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006246213.1
CDS	82..1080
Translation	MEEREWGARSARAGSPASPPSPRLDVSSYSFDPLLALYAPRLPPIPYPNAPCFNNVAEYESFLKGGRTGRGRARGTGEPASAGTSTGTSTGAGTSSRARRRAAPTPDPERIQRLRRLMVVKEDTDGTAGSRRQGPGRSKKAPRNVLTRMPLHEGSPLGELHRCIREGVKVNVHIRTFKGLRGVCTGFLVAFDKFWNMLFDRLKLQDSKKEADSKSAVEDSTLSRYSQTSTWKVASVWGRGDTDRGSHRRSRSVPSSLQASAREESRSELSGRTTRTEGSSVGGTFSRATTLSRGQSRKKKRKPKVDYQQVFTRHINQIFIRGENVLLVHLAQ

Target ORF information:

RefSeq Version	XM_006246151.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus LSM11, U7 small nuclear RNA associated (Lsm11), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006246151.3

ORF Insert Sequence:

ATGGAGGAGC GCGAGTGGGG GGCGAGGTCG GCTCGCGCCG GCAGCCCAGC CAGCCCGCCC 
AGCCCGCGGC TGGACGTCAG CTCCTACAGC TTCGACCCGC TGCTGGCCCT GTACGCGCCG 
CGCCTGCCGC CCATTCCTTA CCCCAACGCT CCCTGCTTCA ACAACGTGGC GGAGTACGAG 
AGCTTCCTGA AGGGCGGGCG CACCGGGCGC GGTCGAGCTC GGGGCACGGG AGAGCCGGCC 
TCGGCGGGAA CCTCCACCGG AACCTCCACG GGAGCCGGGA CCTCGTCCAG GGCCCGTCGC 
CGAGCCGCGC CCACCCCGGA TCCCGAGCGC ATCCAGCGCC TGCGCCGGCT CATGGTGGTC 
AAGGAGGACA CGGACGGCAC GGCCGGGTCG CGACGCCAGG GCCCGGGGCG CAGCAAGAAG 
GCACCCCGCA ACGTGCTCAC GCGGATGCCC TTGCATGAGG GTAGCCCTCT GGGCGAGCTG 
CACCGCTGCA TCCGAGAGGG GGTGAAGGTG AACGTGCACA TCCGCACTTT CAAGGGACTC 
CGCGGCGTCT GCACTGGCTT CCTCGTTGCC TTCGACAAGT TCTGGAACAT GCTATTTGAT 
CGGCTGAAAC TCCAAGATTC CAAAAAGGAA GCGGATTCCA AGTCTGCAGT GGAGGACTCC 
ACCCTGTCTC GTTACTCCCA GACATCTACT TGGAAGGTGG CTTCAGTGTG GGGACGAGGA 
GACACTGACC GAGGCTCACA CAGGCGCTCC CGCTCCGTCC CTTCTTCCCT GCAGGCATCT 
GCAAGGGAGG AGTCCAGGTC TGAGCTGTCA GGGAGGACTA CACGGACAGA AGGGTCCAGT 
GTGGGAGGTA CCTTCTCCAG GGCCACCACC CTTTCACGGG GCCAGTCCCG TAAGAAAAAG 
CGAAAGCCCA AGGTGGATTA CCAGCAAGTG TTTACTCGAC ACATAAATCA GATTTTCATT 
CGAGGTGAGA ATGTCCTGCT GGTTCATCTT GCACAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Three proteins of the U7-specific Sm ring function as the molecular ruler to determine the site of 3'-end processing in mammalian histone pre-mRNA.
Molecular and cellular biology29(15)4045-56(2009 Aug)
Yang XC,Torres MP,Marzluff WF,Dominski Z

Purification of human telomerase complexes identifies factors involved in telomerase biogenesis and telomere length regulation.
Molecular cell28(5)773-85(2007 Dec)
Fu D,Collins K

ZFP100, a component of the active U7 snRNP limiting for histone pre-mRNA processing, is required for entry into S phase.
Molecular and cellular biology26(17)6702-12(2006 Sep)
Wagner EJ,Marzluff WF

Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing.
Genes & development17(18)2321-33(2003 Sep)
Pillai RS,Grimmler M,Meister G,Will CL,L?hrmann R,Fischer U,Sch?mperli D

Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein.
The EMBO journal20(19)5470-9(2001 Oct)
Pillai RS,Will CL,L?hrmann R,Sch?mperli D,M?ller B

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Lsm11 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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