Cactin cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cactin
Entrez Gene ID	500790
Full Name	cactin, spliceosome C complex subunit
Synonyms	RGD1563634
General protein information	Preferred Names cactin, spliceosome C complex subunit Names cactin
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q11

mRNA and Protein(s)

mRNA	Protein	Name
NM_001081447.1	NP_001074916.1	cactin
XM_008765126.2	XP_008763348.1	cactin isoform X1

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	cactin	NP_523422.3
Pan troglodytes (chimpanzee)	CACTIN	XP_001135512.2
	LOC721737	XP_002801071.1
Canis lupus familiaris (dog)	CACTIN	XP_542173.3
Mus musculus (house mouse)	Cactin	NP_081657.1
Homo sapiens (human)	CACTIN	NP_067054.1
Rattus norvegicus (Norway rat)	Cactin	NP_001074916.1
Gallus gallus (chicken)	CACTIN	XP_418192.3
Caenorhabditis elegans (roundworm)	cacn-1	NP_001254420.1
Xenopus tropicalis (tropical clawed frog)	cactin	XP_002942250.2
Danio rerio (zebrafish)	cactin	XP_005168489.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006542	XP_316580.4
Caenorhabditis elegans (roundworm)	cacn-1	NP_001254422.1
Arabidopsis thaliana (thale cress)	AT1G03910	NP_171887.1

Gene Ontology
Bibliography

Related articles in PubMed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanh?usser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

Cactin targets the MHC class III protein IkappaB-like (IkappaBL) and inhibits NF-kappaB and interferon-regulatory factor signaling pathways.
Atzei P, Gargan S, Curran N, Moynagh PN
The Journal of biological chemistry285(47)36804-17(2010 Nov)

Large-scale characterization of HeLa cell nuclear phosphoproteins.
Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Vill?n J, Li J, Cohn MA, Cantley LC, Gygi SP
Proceedings of the National Academy of Sciences of the United States of America101(33)12130-5(2004 Aug)

Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.
Jurica MS, Licklider LJ, Gygi SR, Grigorieff N, Moore MJ
RNA (New York, N.Y.)8(4)426-39(2002 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cactin gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cactin cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa10763	NM_001081447.1 Latest version!	Rattus norvegicus cactin, spliceosome C complex subunit (Cactin), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
ORa10763	XM_008765126.2 Latest version!	Rattus norvegicus cactin, spliceosome C complex subunit (Cactin), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cactin ( NM_001081447.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001074916.1 Rattus norvegicus cactin, spliceosome C complex subunit (Cactin), mRNA.

Price & Availability↑

CloneID	ORa10763
Clone ID Related Accession (Same CDS sequence)	NM_001081447.1 , XM_008765126.2
Accession Version	NM_001081447.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2292bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Rattus norvegicus(Norway rat)
Product	cactin
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY934505.1. On Feb 8, 2007 this sequence version replaced XR_009036.1. ##Evidence-Data-START## Transcript exon combination :: AY934505.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906348, SAMN01906349 [ECO:0000348] ##Evidence-Data-END##

ATGCGCGGCG CGGGCCGCCA AATGGGTTCG CACTCTCGCT CGCGCTCACG ATCTGCGGGT 
CGTAGGAGTC GGAAGCAGCG GAGTAGGAGT AGAAGCTGCA GCAGGAGCCG GAGCCGAAGC 
CGGAGCCGGA GCCGGAGCCG GAGCCATGGG GGGAGCGGCC GAAGGCGACG GGAACATGAG 
CGGCGGCGCG AACGCAAACG GCGCAGTCGA GGGCGCAGGT CAGATTCGGA AGGAAACCGT 
GTGCAGAAGT CTAGGAGGCG AAGCCGGAGC CTTCGGCCAC CCCGATGGCA CTCACAGGAC 
CGGTCCTCAC ACTCTGACTC GGGTGAGGAG CAAGCACAGG GCTCCCGAGC CCGGAAGGGT 
CACAGGCATT CGTGGTCCCC AGGGTCATCA GCATCTAGCT CTGACTCCCC AAGACGCTCC 
CGGAGTCCTG GAGTAGCTGC CCTGGCCGCG AGTCAGCAGC AGAGCCTTCA GGAACGGCTG 
CGGCTTCGTG AGGAGCGAAA GCAGCAAGAA GAGCTGCTCA AGGCCTTCGA GACACCCGAG 
GAGAAGCGTG CCCGGCGACT GGCCAAGAAA GAAGCTAAGG AGCGCAAGAA GCGTGAGAAG 
ATGGGCTGGG GTGAGGAGTA CATGGGCTAC ACCAACACCG ACAACCCCTT TGGAGACAAC 
AACCTGCTGG GCACTTTTAT CTGGAACAAA GCCTTGGAGA AAAAAGGCAT CGGTCACCTG 
GAGGAAAAGG AGCTGAAGGA ACGTAACAAG AGGATCCAGG AGGAGAACCG GCTAGAGCTG 
CAAAAGGTAA AACAGCTGCG GCTGGAGCGG GAACGGGAGA AGGCCATGCG GGAGCAGGAA 
CTGGAACTGT TGCAACGGGA GAAGGAGGCA GAGCACTTTA AGACCTGGGA GGAGCAGGAG 
GACAGCTTCC ACTTGCGGCA GGCCAAGCTT CGTTCCAAGA TCCGAATCCG AGACGGGCGG 
GCCAAGCCCA TTGACTTGCT GGCCAAGTAC ATCAGTGCAG AGGACGATGA CCTGGCAGTG 
GAGATGCATG AACCTTACAC CTTCCTCAAC GGCCTCACGG TGGCAGACAT GGAGGACCTG 
CTAGAGGACA TCCAGGTGTA CATGGAGCTG GAGCAGGGCA AGAACGTGGA CTTCTGGCGA 
GACATGACAA CCATCACAGA GGATGAGATT GCCAAGCTCC GCAAGCTGGA GGCCTCGGGC 
AAGGGCCCAG GTGAGCGCCG TGAGGGGGTC AACGCCTCGG TCAGCTCTGA CGTGCAGTCC 
GTCTTCAAGG GAAAGACGTA CAACCAGCTG CAGGTCATCT TCCAGGGCAT CGAAGGCAAG 
ATCCGTGCCG GCGGCCCCAA CCTCGACATG GGCTACTGGG AGAGCCTGCT GCAGCAGTTG 
CGCGCGCACA TGGCCAGGGC CAGGCTCCGT GAGCGCCACC AAGATGTCCT TAGACAGAAG 
CTGTTCAAAC TGAAGCAGGA GCAGGGTGTG GAGAGTGAGC CGCTGTTTCC CATCCTCAAG 
TCAGAGCCCA CAGCCACTCA CAGCCCTGAA CCTGAGGAAC GGCCTCCCAG CCCTGGGACT 
TCAGTGGACC CCGTGGAACC CGAGGAGACC ACAGCAGCAG GCGAGGCAGA GGGAGAGGCA 
GATGGCGAGG CAGTGCTGAT GGAGGAGGAC CTGATCCAGC AGAGCCTGGC AGACTATGAC 
GCTGGCCGCT ACAGCCCACG ACTGCTCACC GCGCACGAGT TGCCTTTGGA CGCGCATGTG 
CTGGAGCCGC ATGAGGACCT GCAGCGCCTG CAGCTGTCTC GCCAGCAGCT TCAGGCTACA 
GGTGACGCGA GCGAGAGTGC TGAGGACATC TTCTTCCGGC GTGCGAGGGA GGGCATGGGG 
CAGGATGAGG CACAGTTCAG CGTGGAGATG CCACTGGGTG GCCGCGCCTA CCTGTGGGCC 
GACAAGTATC GGCCGCGGAA GCCGCGATTC TTTAACCGTG TGCACACAGG CTTTGAATGG 
AACAAATATA ACCAGACACA TTATGACTTT GACAACCCTC CACCCAAGAT CGTGCAGGGC 
TACAAATTTA ACATCTTCTA CCCGGACCTC ATCCGCAAAC GTGCCACACC AGAGTACTTC 
CTGGAGGCCT GCGCTGACAA CCGGGACTTT GCCATCCTGC GTTTCCACGC AGGCCCGCCC 
TACGAGGACA TCGCCTTCAA GATCGTCAGT CGAGAATGGG AGTACTCGCA CCGCCATGGC 
TTCCGCTGCC AGTTTGCCAA TGGAATCTTC CAGCTCTGGT TCCACTTCAA GCGCTACCGC 
TACCGCCGGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001074916.1
CDS	6..2297
Translation	MRGAGRQMGSHSRSRSRSAGRRSRKQRSRSRSCSRSRSRSRSRSRSRSHGGSGRRRREHERRRERKRRSRGRRSDSEGNRVQKSRRRSRSLRPPRWHSQDRSSHSDSGEEQAQGSRARKGHRHSWSPGSSASSSDSPRRSRSPGVAALAASQQQSLQERLRLREERKQQEELLKAFETPEEKRARRLAKKEAKERKKREKMGWGEEYMGYTNTDNPFGDNNLLGTFIWNKALEKKGIGHLEEKELKERNKRIQEENRLELQKVKQLRLEREREKAMREQELELLQREKEAEHFKTWEEQEDSFHLRQAKLRSKIRIRDGRAKPIDLLAKYISAEDDDLAVEMHEPYTFLNGLTVADMEDLLEDIQVYMELEQGKNVDFWRDMTTITEDEIAKLRKLEASGKGPGERREGVNASVSSDVQSVFKGKTYNQLQVIFQGIEGKIRAGGPNLDMGYWESLLQQLRAHMARARLRERHQDVLRQKLFKLKQEQGVESEPLFPILKSEPTATHSPEPEERPPSPGTSVDPVEPEETTAAGEAEGEADGEAVLMEEDLIQQSLADYDAGRYSPRLLTAHELPLDAHVLEPHEDLQRLQLSRQQLQATGDASESAEDIFFRRAREGMGQDEAQFSVEMPLGGRAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIRKRATPEYFLEACADNRDFAILRFHAGPPYEDIAFKIVSREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR

Target ORF information:

RefSeq Version	NM_001081447.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cactin, spliceosome C complex subunit (Cactin), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001081447.1

ORF Insert Sequence:

ATGCGCGGCG CGGGCCGCCA AATGGGTTCG CACTCTCGCT CGCGCTCACG ATCTGCGGGT 
CGTAGGAGTC GGAAGCAGCG GAGTAGGAGT AGAAGCTGCA GCAGGAGCCG GAGCCGAAGC 
CGGAGCCGGA GCCGGAGCCG GAGCCATGGG GGGAGCGGCC GAAGGCGACG GGAACATGAG 
CGGCGGCGCG AACGCAAACG GCGCAGTCGA GGGCGCAGGT CAGATTCGGA AGGAAACCGT 
GTGCAGAAGT CTAGGAGGCG AAGCCGGAGC CTTCGGCCAC CCCGATGGCA CTCACAGGAC 
CGGTCCTCAC ACTCTGACTC GGGTGAGGAG CAAGCACAGG GCTCCCGAGC CCGGAAGGGT 
CACAGGCATT CGTGGTCCCC AGGGTCATCA GCATCTAGCT CTGACTCCCC AAGACGCTCC 
CGGAGTCCTG GAGTAGCTGC CCTGGCCGCG AGTCAGCAGC AGAGCCTTCA GGAACGGCTG 
CGGCTTCGTG AGGAGCGAAA GCAGCAAGAA GAGCTGCTCA AGGCCTTCGA GACACCCGAG 
GAGAAGCGTG CCCGGCGACT GGCCAAGAAA GAAGCTAAGG AGCGCAAGAA GCGTGAGAAG 
ATGGGCTGGG GTGAGGAGTA CATGGGCTAC ACCAACACCG ACAACCCCTT TGGAGACAAC 
AACCTGCTGG GCACTTTTAT CTGGAACAAA GCCTTGGAGA AAAAAGGCAT CGGTCACCTG 
GAGGAAAAGG AGCTGAAGGA ACGTAACAAG AGGATCCAGG AGGAGAACCG GCTAGAGCTG 
CAAAAGGTAA AACAGCTGCG GCTGGAGCGG GAACGGGAGA AGGCCATGCG GGAGCAGGAA 
CTGGAACTGT TGCAACGGGA GAAGGAGGCA GAGCACTTTA AGACCTGGGA GGAGCAGGAG 
GACAGCTTCC ACTTGCGGCA GGCCAAGCTT CGTTCCAAGA TCCGAATCCG AGACGGGCGG 
GCCAAGCCCA TTGACTTGCT GGCCAAGTAC ATCAGTGCAG AGGACGATGA CCTGGCAGTG 
GAGATGCATG AACCTTACAC CTTCCTCAAC GGCCTCACGG TGGCAGACAT GGAGGACCTG 
CTAGAGGACA TCCAGGTGTA CATGGAGCTG GAGCAGGGCA AGAACGTGGA CTTCTGGCGA 
GACATGACAA CCATCACAGA GGATGAGATT GCCAAGCTCC GCAAGCTGGA GGCCTCGGGC 
AAGGGCCCAG GTGAGCGCCG TGAGGGGGTC AACGCCTCGG TCAGCTCTGA CGTGCAGTCC 
GTCTTCAAGG GAAAGACGTA CAACCAGCTG CAGGTCATCT TCCAGGGCAT CGAAGGCAAG 
ATCCGTGCCG GCGGCCCCAA CCTCGACATG GGCTACTGGG AGAGCCTGCT GCAGCAGTTG 
CGCGCGCACA TGGCCAGGGC CAGGCTCCGT GAGCGCCACC AAGATGTCCT TAGACAGAAG 
CTGTTCAAAC TGAAGCAGGA GCAGGGTGTG GAGAGTGAGC CGCTGTTTCC CATCCTCAAG 
TCAGAGCCCA CAGCCACTCA CAGCCCTGAA CCTGAGGAAC GGCCTCCCAG CCCTGGGACT 
TCAGTGGACC CCGTGGAACC CGAGGAGACC ACAGCAGCAG GCGAGGCAGA GGGAGAGGCA 
GATGGCGAGG CAGTGCTGAT GGAGGAGGAC CTGATCCAGC AGAGCCTGGC AGACTATGAC 
GCTGGCCGCT ACAGCCCACG ACTGCTCACC GCGCACGAGT TGCCTTTGGA CGCGCATGTG 
CTGGAGCCGC ATGAGGACCT GCAGCGCCTG CAGCTGTCTC GCCAGCAGCT TCAGGCTACA 
GGTGACGCGA GCGAGAGTGC TGAGGACATC TTCTTCCGGC GTGCGAGGGA GGGCATGGGG 
CAGGATGAGG CACAGTTCAG CGTGGAGATG CCACTGGGTG GCCGCGCCTA CCTGTGGGCC 
GACAAGTATC GGCCGCGGAA GCCGCGATTC TTTAACCGTG TGCACACAGG CTTTGAATGG 
AACAAATATA ACCAGACACA TTATGACTTT GACAACCCTC CACCCAAGAT CGTGCAGGGC 
TACAAATTTA ACATCTTCTA CCCGGACCTC ATCCGCAAAC GTGCCACACC AGAGTACTTC 
CTGGAGGCCT GCGCTGACAA CCGGGACTTT GCCATCCTGC GTTTCCACGC AGGCCCGCCC 
TACGAGGACA TCGCCTTCAA GATCGTCAGT CGAGAATGGG AGTACTCGCA CCGCCATGGC 
TTCCGCTGCC AGTTTGCCAA TGGAATCTTC CAGCTCTGGT TCCACTTCAA GCGCTACCGC 
TACCGCCGGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cactin ( XM_008765126.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008763348.1 Rattus norvegicus cactin, spliceosome C complex subunit (Cactin), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa10763
Clone ID Related Accession (Same CDS sequence)	NM_001081447.1 , XM_008765126.2
Accession Version	XM_008765126.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2292bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	cactin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008765126.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGCGGCG CGGGCCGCCA AATGGGTTCG CACTCTCGCT CGCGCTCACG ATCTGCGGGT 
CGTAGGAGTC GGAAGCAGCG GAGTAGGAGT AGAAGCTGCA GCAGGAGCCG GAGCCGAAGC 
CGGAGCCGGA GCCGGAGCCG GAGCCATGGG GGGAGCGGCC GAAGGCGACG GGAACATGAG 
CGGCGGCGCG AACGCAAACG GCGCAGTCGA GGGCGCAGGT CAGATTCGGA AGGAAACCGT 
GTGCAGAAGT CTAGGAGGCG AAGCCGGAGC CTTCGGCCAC CCCGATGGCA CTCACAGGAC 
CGGTCCTCAC ACTCTGACTC GGGTGAGGAG CAAGCACAGG GCTCCCGAGC CCGGAAGGGT 
CACAGGCATT CGTGGTCCCC AGGGTCATCA GCATCTAGCT CTGACTCCCC AAGACGCTCC 
CGGAGTCCTG GAGTAGCTGC CCTGGCCGCG AGTCAGCAGC AGAGCCTTCA GGAACGGCTG 
CGGCTTCGTG AGGAGCGAAA GCAGCAAGAA GAGCTGCTCA AGGCCTTCGA GACACCCGAG 
GAGAAGCGTG CCCGGCGACT GGCCAAGAAA GAAGCTAAGG AGCGCAAGAA GCGTGAGAAG 
ATGGGCTGGG GTGAGGAGTA CATGGGCTAC ACCAACACCG ACAACCCCTT TGGAGACAAC 
AACCTGCTGG GCACTTTTAT CTGGAACAAA GCCTTGGAGA AAAAAGGCAT CGGTCACCTG 
GAGGAAAAGG AGCTGAAGGA ACGTAACAAG AGGATCCAGG AGGAGAACCG GCTAGAGCTG 
CAAAAGGTAA AACAGCTGCG GCTGGAGCGG GAACGGGAGA AGGCCATGCG GGAGCAGGAA 
CTGGAACTGT TGCAACGGGA GAAGGAGGCA GAGCACTTTA AGACCTGGGA GGAGCAGGAG 
GACAGCTTCC ACTTGCGGCA GGCCAAGCTT CGTTCCAAGA TCCGAATCCG AGACGGGCGG 
GCCAAGCCCA TTGACTTGCT GGCCAAGTAC ATCAGTGCAG AGGACGATGA CCTGGCAGTG 
GAGATGCATG AACCTTACAC CTTCCTCAAC GGCCTCACGG TGGCAGACAT GGAGGACCTG 
CTAGAGGACA TCCAGGTGTA CATGGAGCTG GAGCAGGGCA AGAACGTGGA CTTCTGGCGA 
GACATGACAA CCATCACAGA GGATGAGATT GCCAAGCTCC GCAAGCTGGA GGCCTCGGGC 
AAGGGCCCAG GTGAGCGCCG TGAGGGGGTC AACGCCTCGG TCAGCTCTGA CGTGCAGTCC 
GTCTTCAAGG GAAAGACGTA CAACCAGCTG CAGGTCATCT TCCAGGGCAT CGAAGGCAAG 
ATCCGTGCCG GCGGCCCCAA CCTCGACATG GGCTACTGGG AGAGCCTGCT GCAGCAGTTG 
CGCGCGCACA TGGCCAGGGC CAGGCTCCGT GAGCGCCACC AAGATGTCCT TAGACAGAAG 
CTGTTCAAAC TGAAGCAGGA GCAGGGTGTG GAGAGTGAGC CGCTGTTTCC CATCCTCAAG 
TCAGAGCCCA CAGCCACTCA CAGCCCTGAA CCTGAGGAAC GGCCTCCCAG CCCTGGGACT 
TCAGTGGACC CCGTGGAACC CGAGGAGACC ACAGCAGCAG GCGAGGCAGA GGGAGAGGCA 
GATGGCGAGG CAGTGCTGAT GGAGGAGGAC CTGATCCAGC AGAGCCTGGC AGACTATGAC 
GCTGGCCGCT ACAGCCCACG ACTGCTCACC GCGCACGAGT TGCCTTTGGA CGCGCATGTG 
CTGGAGCCGC ATGAGGACCT GCAGCGCCTG CAGCTGTCTC GCCAGCAGCT TCAGGCTACA 
GGTGACGCGA GCGAGAGTGC TGAGGACATC TTCTTCCGGC GTGCGAGGGA GGGCATGGGG 
CAGGATGAGG CACAGTTCAG CGTGGAGATG CCACTGGGTG GCCGCGCCTA CCTGTGGGCC 
GACAAGTATC GGCCGCGGAA GCCGCGATTC TTTAACCGTG TGCACACAGG CTTTGAATGG 
AACAAATATA ACCAGACACA TTATGACTTT GACAACCCTC CACCCAAGAT CGTGCAGGGC 
TACAAATTTA ACATCTTCTA CCCGGACCTC ATCCGCAAAC GTGCCACACC AGAGTACTTC 
CTGGAGGCCT GCGCTGACAA CCGGGACTTT GCCATCCTGC GTTTCCACGC AGGCCCGCCC 
TACGAGGACA TCGCCTTCAA GATCGTCAGT CGAGAATGGG AGTACTCGCA CCGCCATGGC 
TTCCGCTGCC AGTTTGCCAA TGGAATCTTC CAGCTCTGGT TCCACTTCAA GCGCTACCGC 
TACCGCCGGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008763348.1
CDS	512..2803
Translation	MRGAGRQMGSHSRSRSRSAGRRSRKQRSRSRSCSRSRSRSRSRSRSRSHGGSGRRRREHERRRERKRRSRGRRSDSEGNRVQKSRRRSRSLRPPRWHSQDRSSHSDSGEEQAQGSRARKGHRHSWSPGSSASSSDSPRRSRSPGVAALAASQQQSLQERLRLREERKQQEELLKAFETPEEKRARRLAKKEAKERKKREKMGWGEEYMGYTNTDNPFGDNNLLGTFIWNKALEKKGIGHLEEKELKERNKRIQEENRLELQKVKQLRLEREREKAMREQELELLQREKEAEHFKTWEEQEDSFHLRQAKLRSKIRIRDGRAKPIDLLAKYISAEDDDLAVEMHEPYTFLNGLTVADMEDLLEDIQVYMELEQGKNVDFWRDMTTITEDEIAKLRKLEASGKGPGERREGVNASVSSDVQSVFKGKTYNQLQVIFQGIEGKIRAGGPNLDMGYWESLLQQLRAHMARARLRERHQDVLRQKLFKLKQEQGVESEPLFPILKSEPTATHSPEPEERPPSPGTSVDPVEPEETTAAGEAEGEADGEAVLMEEDLIQQSLADYDAGRYSPRLLTAHELPLDAHVLEPHEDLQRLQLSRQQLQATGDASESAEDIFFRRAREGMGQDEAQFSVEMPLGGRAYLWADKYRPRKPRFFNRVHTGFEWNKYNQTHYDFDNPPPKIVQGYKFNIFYPDLIRKRATPEYFLEACADNRDFAILRFHAGPPYEDIAFKIVSREWEYSHRHGFRCQFANGIFQLWFHFKRYRYRR

Target ORF information:

RefSeq Version	XM_008765126.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cactin, spliceosome C complex subunit (Cactin), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008765126.2

ORF Insert Sequence:

ATGCGCGGCG CGGGCCGCCA AATGGGTTCG CACTCTCGCT CGCGCTCACG ATCTGCGGGT 
CGTAGGAGTC GGAAGCAGCG GAGTAGGAGT AGAAGCTGCA GCAGGAGCCG GAGCCGAAGC 
CGGAGCCGGA GCCGGAGCCG GAGCCATGGG GGGAGCGGCC GAAGGCGACG GGAACATGAG 
CGGCGGCGCG AACGCAAACG GCGCAGTCGA GGGCGCAGGT CAGATTCGGA AGGAAACCGT 
GTGCAGAAGT CTAGGAGGCG AAGCCGGAGC CTTCGGCCAC CCCGATGGCA CTCACAGGAC 
CGGTCCTCAC ACTCTGACTC GGGTGAGGAG CAAGCACAGG GCTCCCGAGC CCGGAAGGGT 
CACAGGCATT CGTGGTCCCC AGGGTCATCA GCATCTAGCT CTGACTCCCC AAGACGCTCC 
CGGAGTCCTG GAGTAGCTGC CCTGGCCGCG AGTCAGCAGC AGAGCCTTCA GGAACGGCTG 
CGGCTTCGTG AGGAGCGAAA GCAGCAAGAA GAGCTGCTCA AGGCCTTCGA GACACCCGAG 
GAGAAGCGTG CCCGGCGACT GGCCAAGAAA GAAGCTAAGG AGCGCAAGAA GCGTGAGAAG 
ATGGGCTGGG GTGAGGAGTA CATGGGCTAC ACCAACACCG ACAACCCCTT TGGAGACAAC 
AACCTGCTGG GCACTTTTAT CTGGAACAAA GCCTTGGAGA AAAAAGGCAT CGGTCACCTG 
GAGGAAAAGG AGCTGAAGGA ACGTAACAAG AGGATCCAGG AGGAGAACCG GCTAGAGCTG 
CAAAAGGTAA AACAGCTGCG GCTGGAGCGG GAACGGGAGA AGGCCATGCG GGAGCAGGAA 
CTGGAACTGT TGCAACGGGA GAAGGAGGCA GAGCACTTTA AGACCTGGGA GGAGCAGGAG 
GACAGCTTCC ACTTGCGGCA GGCCAAGCTT CGTTCCAAGA TCCGAATCCG AGACGGGCGG 
GCCAAGCCCA TTGACTTGCT GGCCAAGTAC ATCAGTGCAG AGGACGATGA CCTGGCAGTG 
GAGATGCATG AACCTTACAC CTTCCTCAAC GGCCTCACGG TGGCAGACAT GGAGGACCTG 
CTAGAGGACA TCCAGGTGTA CATGGAGCTG GAGCAGGGCA AGAACGTGGA CTTCTGGCGA 
GACATGACAA CCATCACAGA GGATGAGATT GCCAAGCTCC GCAAGCTGGA GGCCTCGGGC 
AAGGGCCCAG GTGAGCGCCG TGAGGGGGTC AACGCCTCGG TCAGCTCTGA CGTGCAGTCC 
GTCTTCAAGG GAAAGACGTA CAACCAGCTG CAGGTCATCT TCCAGGGCAT CGAAGGCAAG 
ATCCGTGCCG GCGGCCCCAA CCTCGACATG GGCTACTGGG AGAGCCTGCT GCAGCAGTTG 
CGCGCGCACA TGGCCAGGGC CAGGCTCCGT GAGCGCCACC AAGATGTCCT TAGACAGAAG 
CTGTTCAAAC TGAAGCAGGA GCAGGGTGTG GAGAGTGAGC CGCTGTTTCC CATCCTCAAG 
TCAGAGCCCA CAGCCACTCA CAGCCCTGAA CCTGAGGAAC GGCCTCCCAG CCCTGGGACT 
TCAGTGGACC CCGTGGAACC CGAGGAGACC ACAGCAGCAG GCGAGGCAGA GGGAGAGGCA 
GATGGCGAGG CAGTGCTGAT GGAGGAGGAC CTGATCCAGC AGAGCCTGGC AGACTATGAC 
GCTGGCCGCT ACAGCCCACG ACTGCTCACC GCGCACGAGT TGCCTTTGGA CGCGCATGTG 
CTGGAGCCGC ATGAGGACCT GCAGCGCCTG CAGCTGTCTC GCCAGCAGCT TCAGGCTACA 
GGTGACGCGA GCGAGAGTGC TGAGGACATC TTCTTCCGGC GTGCGAGGGA GGGCATGGGG 
CAGGATGAGG CACAGTTCAG CGTGGAGATG CCACTGGGTG GCCGCGCCTA CCTGTGGGCC 
GACAAGTATC GGCCGCGGAA GCCGCGATTC TTTAACCGTG TGCACACAGG CTTTGAATGG 
AACAAATATA ACCAGACACA TTATGACTTT GACAACCCTC CACCCAAGAT CGTGCAGGGC 
TACAAATTTA ACATCTTCTA CCCGGACCTC ATCCGCAAAC GTGCCACACC AGAGTACTTC 
CTGGAGGCCT GCGCTGACAA CCGGGACTTT GCCATCCTGC GTTTCCACGC AGGCCCGCCC 
TACGAGGACA TCGCCTTCAA GATCGTCAGT CGAGAATGGG AGTACTCGCA CCGCCATGGC 
TTCCGCTGCC AGTTTGCCAA TGGAATCTTC CAGCTCTGGT TCCACTTCAA GCGCTACCGC 
TACCGCCGGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanh?usser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M

Cactin targets the MHC class III protein IkappaB-like (IkappaBL) and inhibits NF-kappaB and interferon-regulatory factor signaling pathways.
The Journal of biological chemistry285(47)36804-17(2010 Nov)
Atzei P,Gargan S,Curran N,Moynagh PN

Large-scale characterization of HeLa cell nuclear phosphoproteins.
Proceedings of the National Academy of Sciences of the United States of America101(33)12130-5(2004 Aug)
Beausoleil SA,Jedrychowski M,Schwartz D,Elias JE,Vill?n J,Li J,Cohn MA,Cantley LC,Gygi SP

Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.
RNA (New York, N.Y.)8(4)426-39(2002 Apr)
Jurica MS,Licklider LJ,Gygi SR,Grigorieff N,Moore MJ

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Cactin cDNA ORF clone, Rattus norvegicus(Norway rat)

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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