Dnai1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Dnai1
Entrez Gene ID	500442
Full Name	dynein, axonemal, intermediate chain 1
Synonyms	Dnaic1
General protein information	Preferred Names dynein, axonemal, intermediate chain 1 Names dynein intermediate chain 1, axonemal axonemal dynein intermediate chain 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q22

mRNA and Protein(s)

mRNA	Protein	Name
NM_001024342.1	NP_001019513.1	dynein intermediate chain 1, axonemal

Pathways from BioSystems

Homologies

Homo sapiens (human)	DNAI1	NP_001268357.1
Pan troglodytes (chimpanzee)	DNAI1	XP_520545.2
Gallus gallus (chicken)	DNAI1	XP_003643013.1
Danio rerio (zebrafish)	zgc:158666	NP_001074027.1
	DNAI1	XP_001097717.1
Mus musculus (house mouse)	Dnaic1	NP_780347.2
Rattus norvegicus (Norway rat)	Dnai1	NP_001019513.1
Bos taurus (cattle)	DNAI1	NP_001033231.1
Drosophila melanogaster (fruit fly)	CG9313	NP_611530.5
Canis lupus familiaris (dog)	DNAI1	XP_005626780.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008689	XP_314788.4

Gene Ontology
Bibliography

Related articles in PubMed

Insulin signaling regulates a functional interaction between adenomatous polyposis coli and cytoplasmic dynein.
Gao FJ, Shi L, Hines T, Hebbar S, Neufeld KL, Smith DS
Molecular biology of the cell28(5)587-599(2017 Mar)

Mutations in GAS8, a Gene Encoding a Nexin-Dynein Regulatory Complex Subunit, Cause Primary Ciliary Dyskinesia with Axonemal Disorganization.
Jeanson L, Thomas L, Copin B, Coste A, Sermet-Gaudelus I, Dastot-Le Moal F, Duquesnoy P, Montantin G, Collot N, Tissier S, Papon JF, Clement A, Louis B, Escudier E, Amselem S, Legendre M
Human mutation37(8)776-85(2016 08)

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.
Li Y, Klena NT, Gabriel GC, Liu X, Kim AJ, Lemke K, Chen Y, Chatterjee B, Devine W, Damerla RR, Chang C, Yagi H, San Agustin JT, Thahir M, Anderton S, Lawhead C, Vescovi A, Pratt H, Morgan J, Haynes L, Smith CL, Eppig JT, Reinholdt L, Francis R, Leatherbury L, Ganapathiraju MK, Tobita K, Pazour GJ, Lo CW
Nature521(7553)520-4(2015 May)

High prevalence of respiratory ciliary dysfunction in congenital heart disease patients with heterotaxy.
Nakhleh N, Francis R, Giese RA, Tian X, Li Y, Zariwala MA, Yagi H, Khalifa O, Kureshi S, Chatterjee B, Sabol SL, Swisher M, Connelly PS, Daniels MP, Srinivasan A, Kuehl K, Kravitz N, Burns K, Sami I, Omran H, Barmada M, Olivier K, Chawla KK, Leigh M, Jonas R, Knowles M, Leatherbury L, Lo CW
Circulation125(18)2232-42(2012 May)

Tubulin polyglutamylation is essential for airway ciliary function through the regulation of beating asymmetry.
Ikegami K, Sato S, Nakamura K, Ostrowski LE, Setou M
Proceedings of the National Academy of Sciences of the United States of America107(23)10490-5(2010 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Dnai1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dnai1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06412	NM_001024342.1 Latest version!	Rattus norvegicus dynein, axonemal, intermediate chain 1 (Dnai1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Dnai1 ( NM_001024342.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001019513.1 Rattus norvegicus dynein, axonemal, intermediate chain 1 (Dnai1), mRNA.

Price & Availability↑

CloneID	ORa06412
Clone ID Related Accession (Same CDS sequence)	NM_001024342.1
Accession Version	NM_001024342.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2118bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	dynein intermediate chain 1, axonemal
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC083662.1. On May 27, 2005 this sequence version replaced XM_575804.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC083662.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052297, SAMEA2689599 [ECO:0000348] ##Evidence-Data-END##

ATGCCCTCGA AACAGATTCG TAAGCAGAGT GTCATTTTGA CCAGAGGAGC CAGGAAGCGA 
GAGGAAGACT CAGGGACTGA TGTGGGAGAA GGAGCCGATG ACTGGGCCCA ATCCAAAGCC 
GCTGTGCGGC CCCCTGACCA GCTGGAGCTG ACTGACGCGG AGTTAAAGGA GGAGTTCACT 
CGGATCCTGA CAGCAAACAA CCCACATGCA CCCCAGAATA TTGTCAGGTA CAGCTTCAAA 
GAACGCACAT ACAAGCTTAT TGGTTTTGTG AACCAAATGG CAATTCACTT CAGTCAGGTG 
GGGAACCTGA TACCCAAAGA CTCAGATGAA GGCCGTCGAC AGCACTACCG TGATGAGCTG 
GTGGCAGGTT CACAGGAGTC AGTCAAGGTG GTGACTTCAG ACACAGAAAT CCTTGAAGAA 
GAGGAAGAAC CCAAAGAAGG AGAAGGAGAA GGAGAAGGAG AAGCAGAAGG AGAAGCAGAA 
GCTGGGAGCC AAACGGACGT ACCTGCTGCA GCCGAGACGA CTGAAAAGGT GATTGAAGAA 
GAACTGATGG CTCCTGTGCA GCCCAAGGAG CGAAAACTCA CGAACCAGTT TAACTTCAGC 
GAGCGAGCAT CTCAGACCTT CAACAACCCT CTCCGGGATC GAGAATGTCA GATGGAGCCT 
CCACCTCGGA CAAACTTTTC AGCCACAGCC AATCAGTGGG AGATCTATGA TGCCTATGTA 
GATGAGCTCG AGAAACTGGA AAAGACCAAA GAGAAGGAGA AGACCAAGAC TCCAGTGGCT 
AAGAAAACAG AGAAGATGGC CATGAGGAAA CTAACATCTA TGGAGTCTCA GAGTGATGAT 
ATCACCAAAG TGACCCAAGC TGCTAAAATC GTGGAGCGAA TGGTCAACCA AAATACATAC 
GATGATGTCG CTCAAGATTT TAAGTACTAT GAGGATGCTG CTGATGAATA CAGGGACCAG 
GAGGGTACGC TGCTGCCTCT CTGGAAGTTT CAAAATGACA AAGCCAAGCG CCTGGCCGTC 
ACCGCCCTCT GCTGGAATCC AAAGTACAAG GATCTTTTTG CTGTGGGACA TGGCTCCTAT 
GACTTCATGA AACAGAGTCG GGGCATGCTG CTGCTCTACA GTATGAAGAA CCCTAGTTTC 
CCTGAGTACA TGTTCAGCAG TGAGAGCGGC ATCATGTGTC TGGACATGCA TATGGACCAC 
CCCTACCTGG TGGTCGTGGG CTACTATGAC GGCAACGTGG CCATCTACAA CCTCAAGAAG 
CCTCACTCAC AGCCCTGCTT CCGCAGCACC TCCAAGTCTG GCAAGCACAC GGACCCTGTA 
TGGCAGGTCA AATGGCAGAA GGATGACATG GACCACAACC TTAACTTCTT TTCTGTGTCA 
TCTGATGGCA GGATCGTGTC ATGGACCCTT GTAAAGAGCG AGCTGGTCCA CATCGATGTT 
ATCAAGCTGA AGGACGAAGG CAGCACTACA GAAATCCCTG AGGGGCTGCA GCTGCACACT 
GTAGGCTGTG GCACTGCCTT TGACTTCCAC AAAGAGATTG ACTATCTGTT CCTCGTGGGC 
ACAGAAGAGG GGAAAATCTA CAAGTGCTCC AAATCCTACT CCAGCCAGTT CTTGGACACC 
TATGATGCTC ACAACATGGC AGTAGACGCT GTGTTATGGA ACCCATACCA CGCCAGGGTC 
TTCATATCTT GCAGTTCTGA CTGGACAGTG AAGATCTGGG ACCACGCCAT CAAGACCCCC 
ATGTTCATCT ATGATCTGAA CGCAGCTGTG GGTGACGTGG CCTGGGCACC GTACTCTTCC 
ACTGTGTTTG CAGCAGTCAC CACGGATGGG AAGGCCCACG TGTTTGACTT GGCTGTCAAC 
AAGTATGAAG CCATCTGCAA CCAGCCTGTG GTGGCCAAGA AGAAGAACAA GATTACCCAT 
GTGCAGTTCA ACCCCATTCA CCCCATCATA ATAGTGGGCG ATGACCGTGG ACACATCACC 
TGTCTCAAGC TCTCTCCCAA CTTACGAAAG ATGCCGAAGG AGAAGAAGGG GCAGGAAGTG 
CAGAAGGGTC CAGCTGTGGA GATCGCAAAA TTGGACAAAC TGCTAAACCT TGTGAGGGAA 
GTAAAAACCA AAACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001019513.1
CDS	111..2228
Translation	MPSKQIRKQSVILTRGARKREEDSGTDVGEGADDWAQSKAAVRPPDQLELTDAELKEEFTRILTANNPHAPQNIVRYSFKERTYKLIGFVNQMAIHFSQVGNLIPKDSDEGRRQHYRDELVAGSQESVKVVTSDTEILEEEEEPKEGEGEGEGEAEGEAEAGSQTDVPAAAETTEKVIEEELMAPVQPKERKLTNQFNFSERASQTFNNPLRDRECQMEPPPRTNFSATANQWEIYDAYVDELEKLEKTKEKEKTKTPVAKKTEKMAMRKLTSMESQSDDITKVTQAAKIVERMVNQNTYDDVAQDFKYYEDAADEYRDQEGTLLPLWKFQNDKAKRLAVTALCWNPKYKDLFAVGHGSYDFMKQSRGMLLLYSMKNPSFPEYMFSSESGIMCLDMHMDHPYLVVVGYYDGNVAIYNLKKPHSQPCFRSTSKSGKHTDPVWQVKWQKDDMDHNLNFFSVSSDGRIVSWTLVKSELVHIDVIKLKDEGSTTEIPEGLQLHTVGCGTAFDFHKEIDYLFLVGTEEGKIYKCSKSYSSQFLDTYDAHNMAVDAVLWNPYHARVFISCSSDWTVKIWDHAIKTPMFIYDLNAAVGDVAWAPYSSTVFAAVTTDGKAHVFDLAVNKYEAICNQPVVAKKKNKITHVQFNPIHPIIIVGDDRGHITCLKLSPNLRKMPKEKKGQEVQKGPAVEIAKLDKLLNLVREVKTKT

Target ORF information:

RefSeq Version	NM_001024342.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus dynein, axonemal, intermediate chain 1 (Dnai1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001024342.1

ORF Insert Sequence:

ATGCCCTCGA AACAGATTCG TAAGCAGAGT GTCATTTTGA CCAGAGGAGC CAGGAAGCGA 
GAGGAAGACT CAGGGACTGA TGTGGGAGAA GGAGCCGATG ACTGGGCCCA ATCCAAAGCC 
GCTGTGCGGC CCCCTGACCA GCTGGAGCTG ACTGACGCGG AGTTAAAGGA GGAGTTCACT 
CGGATCCTGA CAGCAAACAA CCCACATGCA CCCCAGAATA TTGTCAGGTA CAGCTTCAAA 
GAACGCACAT ACAAGCTTAT TGGTTTTGTG AACCAAATGG CAATTCACTT CAGTCAGGTG 
GGGAACCTGA TACCCAAAGA CTCAGATGAA GGCCGTCGAC AGCACTACCG TGATGAGCTG 
GTGGCAGGTT CACAGGAGTC AGTCAAGGTG GTGACTTCAG ACACAGAAAT CCTTGAAGAA 
GAGGAAGAAC CCAAAGAAGG AGAAGGAGAA GGAGAAGGAG AAGCAGAAGG AGAAGCAGAA 
GCTGGGAGCC AAACGGACGT ACCTGCTGCA GCCGAGACGA CTGAAAAGGT GATTGAAGAA 
GAACTGATGG CTCCTGTGCA GCCCAAGGAG CGAAAACTCA CGAACCAGTT TAACTTCAGC 
GAGCGAGCAT CTCAGACCTT CAACAACCCT CTCCGGGATC GAGAATGTCA GATGGAGCCT 
CCACCTCGGA CAAACTTTTC AGCCACAGCC AATCAGTGGG AGATCTATGA TGCCTATGTA 
GATGAGCTCG AGAAACTGGA AAAGACCAAA GAGAAGGAGA AGACCAAGAC TCCAGTGGCT 
AAGAAAACAG AGAAGATGGC CATGAGGAAA CTAACATCTA TGGAGTCTCA GAGTGATGAT 
ATCACCAAAG TGACCCAAGC TGCTAAAATC GTGGAGCGAA TGGTCAACCA AAATACATAC 
GATGATGTCG CTCAAGATTT TAAGTACTAT GAGGATGCTG CTGATGAATA CAGGGACCAG 
GAGGGTACGC TGCTGCCTCT CTGGAAGTTT CAAAATGACA AAGCCAAGCG CCTGGCCGTC 
ACCGCCCTCT GCTGGAATCC AAAGTACAAG GATCTTTTTG CTGTGGGACA TGGCTCCTAT 
GACTTCATGA AACAGAGTCG GGGCATGCTG CTGCTCTACA GTATGAAGAA CCCTAGTTTC 
CCTGAGTACA TGTTCAGCAG TGAGAGCGGC ATCATGTGTC TGGACATGCA TATGGACCAC 
CCCTACCTGG TGGTCGTGGG CTACTATGAC GGCAACGTGG CCATCTACAA CCTCAAGAAG 
CCTCACTCAC AGCCCTGCTT CCGCAGCACC TCCAAGTCTG GCAAGCACAC GGACCCTGTA 
TGGCAGGTCA AATGGCAGAA GGATGACATG GACCACAACC TTAACTTCTT TTCTGTGTCA 
TCTGATGGCA GGATCGTGTC ATGGACCCTT GTAAAGAGCG AGCTGGTCCA CATCGATGTT 
ATCAAGCTGA AGGACGAAGG CAGCACTACA GAAATCCCTG AGGGGCTGCA GCTGCACACT 
GTAGGCTGTG GCACTGCCTT TGACTTCCAC AAAGAGATTG ACTATCTGTT CCTCGTGGGC 
ACAGAAGAGG GGAAAATCTA CAAGTGCTCC AAATCCTACT CCAGCCAGTT CTTGGACACC 
TATGATGCTC ACAACATGGC AGTAGACGCT GTGTTATGGA ACCCATACCA CGCCAGGGTC 
TTCATATCTT GCAGTTCTGA CTGGACAGTG AAGATCTGGG ACCACGCCAT CAAGACCCCC 
ATGTTCATCT ATGATCTGAA CGCAGCTGTG GGTGACGTGG CCTGGGCACC GTACTCTTCC 
ACTGTGTTTG CAGCAGTCAC CACGGATGGG AAGGCCCACG TGTTTGACTT GGCTGTCAAC 
AAGTATGAAG CCATCTGCAA CCAGCCTGTG GTGGCCAAGA AGAAGAACAA GATTACCCAT 
GTGCAGTTCA ACCCCATTCA CCCCATCATA ATAGTGGGCG ATGACCGTGG ACACATCACC 
TGTCTCAAGC TCTCTCCCAA CTTACGAAAG ATGCCGAAGG AGAAGAAGGG GCAGGAAGTG 
CAGAAGGGTC CAGCTGTGGA GATCGCAAAA TTGGACAAAC TGCTAAACCT TGTGAGGGAA 
GTAAAAACCA AAACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Insulin signaling regulates a functional interaction between adenomatous polyposis coli and cytoplasmic dynein.
Molecular biology of the cell28(5)587-599(2017 Mar)
Gao FJ,Shi L,Hines T,Hebbar S,Neufeld KL,Smith DS

Mutations in GAS8, a Gene Encoding a Nexin-Dynein Regulatory Complex Subunit, Cause Primary Ciliary Dyskinesia with Axonemal Disorganization.
Human mutation37(8)776-85(2016 08)
Jeanson L,Thomas L,Copin B,Coste A,Sermet-Gaudelus I,Dastot-Le Moal F,Duquesnoy P,Montantin G,Collot N,Tissier S,Papon JF,Clement A,Louis B,Escudier E,Amselem S,Legendre M

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.
Nature521(7553)520-4(2015 May)
Li Y,Klena NT,Gabriel GC,Liu X,Kim AJ,Lemke K,Chen Y,Chatterjee B,Devine W,Damerla RR,Chang C,Yagi H,San Agustin JT,Thahir M,Anderton S,Lawhead C,Vescovi A,Pratt H,Morgan J,Haynes L,Smith CL,Eppig JT,Reinholdt L,Francis R,Leatherbury L,Ganapathiraju MK,Tobita K,Pazour GJ,Lo CW

High prevalence of respiratory ciliary dysfunction in congenital heart disease patients with heterotaxy.
Circulation125(18)2232-42(2012 May)
Nakhleh N,Francis R,Giese RA,Tian X,Li Y,Zariwala MA,Yagi H,Khalifa O,Kureshi S,Chatterjee B,Sabol SL,Swisher M,Connelly PS,Daniels MP,Srinivasan A,Kuehl K,Kravitz N,Burns K,Sami I,Omran H,Barmada M,Olivier K,Chawla KK,Leigh M,Jonas R,Knowles M,Leatherbury L,Lo CW

Tubulin polyglutamylation is essential for airway ciliary function through the regulation of beating asymmetry.
Proceedings of the National Academy of Sciences of the United States of America107(23)10490-5(2010 Jun)
Ikegami K,Sato S,Nakamura K,Ostrowski LE,Setou M

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Dnai1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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