Trim24 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Trim24
Entrez Gene ID	500084
Full Name	tripartite motif-containing 24
General protein information	Preferred Names tripartite motif-containing 24 Names transcription intermediary factor 1-alpha Ab2-427
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q22

mRNA and Protein(s)

mRNA	Protein	Name
NM_001044266.1	NP_001037731.1	transcription intermediary factor 1-alpha

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Readout of epigenetic modifications.
Patel DJ, Wang Z
Annual review of biochemistry8281-118(2013)

TRIM24 links a non-canonical histone signature to breast cancer.
Tsai WW, Wang Z, Yiu TT, Akdemir KC, Xia W, Winter S, Tsai CY, Shi X, Schwarzer D, Plunkett W, Aronow B, Gozani O, Fischle W, Hung MC, Patel DJ, Barton MC
Nature468(7326)927-32(2010 Dec)

TRIM24 mediates ligand-dependent activation of androgen receptor and is repressed by a bromodomain-containing protein, BRD7, in prostate cancer cells.
Kikuchi M, Okumura F, Tsukiyama T, Watanabe M, Miyajima N, Tanaka J, Imamura M, Hatakeyama S
Biochimica et biophysica acta1793(12)1828-36(2009 Dec)

Trim24 targets endogenous p53 for degradation.
Allton K, Jain AK, Herz HM, Tsai WW, Jung SY, Qin J, Bergmann A, Johnson RL, Barton MC
Proceedings of the National Academy of Sciences of the United States of America106(28)11612-6(2009 Jul)

Arterial calcifications and increased expression of vitamin D receptor targets in mice lacking TIF1alpha.
Ignat M, Teletin M, Tisserand J, Khetchoumian K, Dennefeld C, Chambon P, Losson R, Mark M
Proceedings of the National Academy of Sciences of the United States of America105(7)2598-603(2008 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Trim24 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Trim24 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa41968	NM_001044266.1 Latest version!	Rattus norvegicus tripartite motif-containing 24 (Trim24), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Trim24 ( NM_001044266.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001037731.1 Rattus norvegicus tripartite motif-containing 24 (Trim24), mRNA.

Price & Availability↑

CloneID	ORa41968
Clone ID Related Accession (Same CDS sequence)	NM_001044266.1
Accession Version	NM_001044266.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2601bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Rattus norvegicus(Norway rat)
Product	transcription intermediary factor 1-alpha
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY325210.1. On or before Aug 28, 2006 this sequence version replaced XM_575435.2, XM_001067911.1, XM_001066092.1, XM_001066145.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY325210.1 [ECO:0000332] ##Evidence-Data-END##

ATGGCTCAGA GGCAACAGGT GCAACGGAGG CCGGCACCTG TGGGTTCACC AAACCCTAGA 
ATGCAGGGGC CCATCCAGCA GCCTTCCATC TCTCTTCAGC ATCCACCACC ACGCTTAATA 
AACTTTCAGA ACCACAGCCC TAAGCCCAAT GGACCAGTGC TTCCTCCTTA TCCTCAGCAG 
CTGAGGTACC CACCCAGCCA GAATATACCA CGGCAGGCAA TAAAGCCCAA CCCCCTGCAG 
ATGGCTTTTT TGGCTCAACA GGCCATAAAA CAGTGGCAGA TCAGCAGTGG ACAGGCTACG 
CCTACAACTG CCAGCAGCTC CTCCTCCACT CCTTCCAGTC CCACGATCAC AAGTGCAGCT 
GGGTACGATG GAAAAGCTTT CAGTTCACCC ATGATTGATC TGAGTGCACC AGTGGGAGGG 
TCTTACAATC TTCCTTCTCT TCCAGATATT GATTGTTCAA GTACTATCTT GTTGGACAAT 
ATTGCAAGGA AGGATACAAG TGTAGACCCT GGCCAGCCAA GACCTCCATC AAACAGAACC 
GTGCAGTCAC CAAATTCATC AGTGCCGTCT CCAGGCCTGG CAGGGCCTGT TACTATGACT 
AGTGTCCATC CCCCAATACG TTCACCTAGT GCCTCCAGTG TTGGGAGCCG AGGAAGCTCG 
GGCTCTTCCA GCAAACCAGC AGGAGCGGAT TCTACTCACA AGGTCCCAGT AGTCATGCTG 
GAGCCAATTC GAATAAAACA GGAAAACAGT GGACCACCTG AAAACTATGA TTTTCCTGTT 
GTTATAGTAA AACAAGAATC AGATGAAGAA TCTAGACCTC AAAATACTAA CTATCCAAGG 
AGCATACTGA CCTCCCTCCT CCTAAACAGT AGCCAGAGCT CTGCTTCTGA GGAGACGGTG 
TTACGGTCCG ATGCCCCTGA TAGTACAGGA GATCAGCCTG CACTCCATCA TGAAAACTCC 
CCAAATGGAA AGTCTGAGTG GCCGGATGCC TCCCAGAAGT CCCCTGTGCA TGTTGGAGAG 
ACAAGAAAGG AGGATGACCC CAATGAAGAC TGTGGAGAAT GGATTTGTAC TTTCTGCCGG 
GACTTATCTA AGCCAGAAGT TGAATATGAT TGTGATGCTC CCAGTCACAA CTCAGATAAA 
AGGAAAAGTG AAGGCCTTAC TAAACTAACA CCAATAGACA AAAGGAAATG TGAGCGCCTG 
CTCCTGTTCC TTTACTGCCA TGAGATGAGC CTGGCTTTCC AGGACCCCGT CCCTCTGACT 
CCTGATTCTG AAGTAGCCAA TGCCGGTATA AAACTTGAAA GCTATTTTGA AGAACTTCTA 
AAGAATCTTT ATCCAGAGAA GAGGTTCCCT AAGCTAGAAT TCCGGCATGA CGTGGAAGAC 
TGTAAGTTCA GTGACGACTC GGATGATGAC TTTGTGCAAC CCCGGAAGAA GCGCCTCAAG 
AGCATGGAAG ACCGGCAGCT GCTCAAGACC TCAACCAATA TTGACCTCAA GTCTTTAGGG 
ATCTGTGAAA CAATTCCAAT AAGTTCTTAT TTAAAAGAAA AAGAGCGGCT TAGGCAACCA 
ACCGCAGCAC ACAGCCAGCC CAGGCGCCAC GAAGTGTGGA GAAGGAAGCA GAGCGGTGTG 
CGCACGATAA AGAGGGGTGG GCCTGCAGAT GAGAGGCTAG TAATAGCTAT TGCTGAAGAC 
AACATACACT TTGGACAAGG GCTTGGAGGA ACTGAGATGG AATCGACCTG GAAGCCTCCT 
CCCCGAGGAC TAATTCTCAC ATCTAATGAT TCTCAGCAAG CTGCTAAGAG AGAAGAGCAA 
TCACTAGTCC TACCTAGTGG TAAAGCACAA ACCCACAACC ACCAGCAGCA GGGCAACATT 
CCCAGTGGTG CAACAGTGGC ACTGACATCA GCTGACGCTG ACGCCTGTGT GGTCATTAAA 
GATGGTGTTC TCAACGGATA CAGGTTTGAA TTTTACAAAC ACGTTACATT TATTTATTTC 
TCATGTGTGC GTGGCTGTGA ATGCATTCAT GGTGCATGTG GAGGTCAGAG GATAACTCGC 
AGACTCAGAA CTGTCCTTCT ATCACGTAGA TCTGGGGAAC TGAACTCAGA CTATCCTGTT 
TGGCAGCAAG CGTCTTCTCC CAGCATTTGT CACAGTGACA AGTTTGAAGA ACACCCTGAT 
TTTATAAGAA AGGGAAGAGA TCTTGTCTTT GAGAGACTGG ACTTCAGTAG ACTGAACAAG 
AGAGGGGAAA TCCACATCAA ACTCTCTGGT ATCATTTCCA CAGGACGTTT TAAGAAACTT 
GTCAAATGGT TATCAGCAGT CAGAGACGCA CAAGCTGAAA GCTCGCCTGG CACGTCCCAT 
GCATCCGCGC CACTCCCCAA TGCTCACCTC AGCAGTGTAA ATGTAGATGG TGTTGAAGTT 
CGCCGCCACC AGGGCCCTCA GCATGAAGAG GAAGCCAATG AGGCCGGCAC TGAAGAAGAA 
GCAGAGGAAG TTATAGGGAC AGACACAGAG GACCTTCCAG GATGGCCTCA TAAAGCTCTG 
AGCCTTGGCA GGCTGCTGTT CCTCAACCGG CCCAACTGTG GCATCCTAAG CCAGTTTCCT 
CACAATCCAT TCACCAAATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001037731.1
CDS	41..2641
Translation	MAQRQQVQRRPAPVGSPNPRMQGPIQQPSISLQHPPPRLINFQNHSPKPNGPVLPPYPQQLRYPPSQNIPRQAIKPNPLQMAFLAQQAIKQWQISSGQATPTTASSSSSTPSSPTITSAAGYDGKAFSSPMIDLSAPVGGSYNLPSLPDIDCSSTILLDNIARKDTSVDPGQPRPPSNRTVQSPNSSVPSPGLAGPVTMTSVHPPIRSPSASSVGSRGSSGSSSKPAGADSTHKVPVVMLEPIRIKQENSGPPENYDFPVVIVKQESDEESRPQNTNYPRSILTSLLLNSSQSSASEETVLRSDAPDSTGDQPALHHENSPNGKSEWPDASQKSPVHVGETRKEDDPNEDCGEWICTFCRDLSKPEVEYDCDAPSHNSDKRKSEGLTKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTPDSEVANAGIKLESYFEELLKNLYPEKRFPKLEFRHDVEDCKFSDDSDDDFVQPRKKRLKSMEDRQLLKTSTNIDLKSLGICETIPISSYLKEKERLRQPTAAHSQPRRHEVWRRKQSGVRTIKRGGPADERLVIAIAEDNIHFGQGLGGTEMESTWKPPPRGLILTSNDSQQAAKREEQSLVLPSGKAQTHNHQQQGNIPSGATVALTSADADACVVIKDGVLNGYRFEFYKHVTFIYFSCVRGCECIHGACGGQRITRRLRTVLLSRRSGELNSDYPVWQQASSPSICHSDKFEEHPDFIRKGRDLVFERLDFSRLNKRGEIHIKLSGIISTGRFKKLVKWLSAVRDAQAESSPGTSHASAPLPNAHLSSVNVDGVEVRRHQGPQHEEEANEAGTEEEAEEVIGTDTEDLPGWPHKALSLGRLLFLNRPNCGILSQFPHNPFTK

Target ORF information:

RefSeq Version	NM_001044266.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus tripartite motif-containing 24 (Trim24), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001044266.1

ORF Insert Sequence:

ATGGCTCAGA GGCAACAGGT GCAACGGAGG CCGGCACCTG TGGGTTCACC AAACCCTAGA 
ATGCAGGGGC CCATCCAGCA GCCTTCCATC TCTCTTCAGC ATCCACCACC ACGCTTAATA 
AACTTTCAGA ACCACAGCCC TAAGCCCAAT GGACCAGTGC TTCCTCCTTA TCCTCAGCAG 
CTGAGGTACC CACCCAGCCA GAATATACCA CGGCAGGCAA TAAAGCCCAA CCCCCTGCAG 
ATGGCTTTTT TGGCTCAACA GGCCATAAAA CAGTGGCAGA TCAGCAGTGG ACAGGCTACG 
CCTACAACTG CCAGCAGCTC CTCCTCCACT CCTTCCAGTC CCACGATCAC AAGTGCAGCT 
GGGTACGATG GAAAAGCTTT CAGTTCACCC ATGATTGATC TGAGTGCACC AGTGGGAGGG 
TCTTACAATC TTCCTTCTCT TCCAGATATT GATTGTTCAA GTACTATCTT GTTGGACAAT 
ATTGCAAGGA AGGATACAAG TGTAGACCCT GGCCAGCCAA GACCTCCATC AAACAGAACC 
GTGCAGTCAC CAAATTCATC AGTGCCGTCT CCAGGCCTGG CAGGGCCTGT TACTATGACT 
AGTGTCCATC CCCCAATACG TTCACCTAGT GCCTCCAGTG TTGGGAGCCG AGGAAGCTCG 
GGCTCTTCCA GCAAACCAGC AGGAGCGGAT TCTACTCACA AGGTCCCAGT AGTCATGCTG 
GAGCCAATTC GAATAAAACA GGAAAACAGT GGACCACCTG AAAACTATGA TTTTCCTGTT 
GTTATAGTAA AACAAGAATC AGATGAAGAA TCTAGACCTC AAAATACTAA CTATCCAAGG 
AGCATACTGA CCTCCCTCCT CCTAAACAGT AGCCAGAGCT CTGCTTCTGA GGAGACGGTG 
TTACGGTCCG ATGCCCCTGA TAGTACAGGA GATCAGCCTG CACTCCATCA TGAAAACTCC 
CCAAATGGAA AGTCTGAGTG GCCGGATGCC TCCCAGAAGT CCCCTGTGCA TGTTGGAGAG 
ACAAGAAAGG AGGATGACCC CAATGAAGAC TGTGGAGAAT GGATTTGTAC TTTCTGCCGG 
GACTTATCTA AGCCAGAAGT TGAATATGAT TGTGATGCTC CCAGTCACAA CTCAGATAAA 
AGGAAAAGTG AAGGCCTTAC TAAACTAACA CCAATAGACA AAAGGAAATG TGAGCGCCTG 
CTCCTGTTCC TTTACTGCCA TGAGATGAGC CTGGCTTTCC AGGACCCCGT CCCTCTGACT 
CCTGATTCTG AAGTAGCCAA TGCCGGTATA AAACTTGAAA GCTATTTTGA AGAACTTCTA 
AAGAATCTTT ATCCAGAGAA GAGGTTCCCT AAGCTAGAAT TCCGGCATGA CGTGGAAGAC 
TGTAAGTTCA GTGACGACTC GGATGATGAC TTTGTGCAAC CCCGGAAGAA GCGCCTCAAG 
AGCATGGAAG ACCGGCAGCT GCTCAAGACC TCAACCAATA TTGACCTCAA GTCTTTAGGG 
ATCTGTGAAA CAATTCCAAT AAGTTCTTAT TTAAAAGAAA AAGAGCGGCT TAGGCAACCA 
ACCGCAGCAC ACAGCCAGCC CAGGCGCCAC GAAGTGTGGA GAAGGAAGCA GAGCGGTGTG 
CGCACGATAA AGAGGGGTGG GCCTGCAGAT GAGAGGCTAG TAATAGCTAT TGCTGAAGAC 
AACATACACT TTGGACAAGG GCTTGGAGGA ACTGAGATGG AATCGACCTG GAAGCCTCCT 
CCCCGAGGAC TAATTCTCAC ATCTAATGAT TCTCAGCAAG CTGCTAAGAG AGAAGAGCAA 
TCACTAGTCC TACCTAGTGG TAAAGCACAA ACCCACAACC ACCAGCAGCA GGGCAACATT 
CCCAGTGGTG CAACAGTGGC ACTGACATCA GCTGACGCTG ACGCCTGTGT GGTCATTAAA 
GATGGTGTTC TCAACGGATA CAGGTTTGAA TTTTACAAAC ACGTTACATT TATTTATTTC 
TCATGTGTGC GTGGCTGTGA ATGCATTCAT GGTGCATGTG GAGGTCAGAG GATAACTCGC 
AGACTCAGAA CTGTCCTTCT ATCACGTAGA TCTGGGGAAC TGAACTCAGA CTATCCTGTT 
TGGCAGCAAG CGTCTTCTCC CAGCATTTGT CACAGTGACA AGTTTGAAGA ACACCCTGAT 
TTTATAAGAA AGGGAAGAGA TCTTGTCTTT GAGAGACTGG ACTTCAGTAG ACTGAACAAG 
AGAGGGGAAA TCCACATCAA ACTCTCTGGT ATCATTTCCA CAGGACGTTT TAAGAAACTT 
GTCAAATGGT TATCAGCAGT CAGAGACGCA CAAGCTGAAA GCTCGCCTGG CACGTCCCAT 
GCATCCGCGC CACTCCCCAA TGCTCACCTC AGCAGTGTAA ATGTAGATGG TGTTGAAGTT 
CGCCGCCACC AGGGCCCTCA GCATGAAGAG GAAGCCAATG AGGCCGGCAC TGAAGAAGAA 
GCAGAGGAAG TTATAGGGAC AGACACAGAG GACCTTCCAG GATGGCCTCA TAAAGCTCTG 
AGCCTTGGCA GGCTGCTGTT CCTCAACCGG CCCAACTGTG GCATCCTAAG CCAGTTTCCT 
CACAATCCAT TCACCAAATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Readout of epigenetic modifications.
Annual review of biochemistry8281-118(2013)
Patel DJ,Wang Z

TRIM24 links a non-canonical histone signature to breast cancer.
Nature468(7326)927-32(2010 Dec)
Tsai WW,Wang Z,Yiu TT,Akdemir KC,Xia W,Winter S,Tsai CY,Shi X,Schwarzer D,Plunkett W,Aronow B,Gozani O,Fischle W,Hung MC,Patel DJ,Barton MC

TRIM24 mediates ligand-dependent activation of androgen receptor and is repressed by a bromodomain-containing protein, BRD7, in prostate cancer cells.
Biochimica et biophysica acta1793(12)1828-36(2009 Dec)
Kikuchi M,Okumura F,Tsukiyama T,Watanabe M,Miyajima N,Tanaka J,Imamura M,Hatakeyama S

Trim24 targets endogenous p53 for degradation.
Proceedings of the National Academy of Sciences of the United States of America106(28)11612-6(2009 Jul)
Allton K,Jain AK,Herz HM,Tsai WW,Jung SY,Qin J,Bergmann A,Johnson RL,Barton MC

Arterial calcifications and increased expression of vitamin D receptor targets in mice lacking TIF1alpha.
Proceedings of the National Academy of Sciences of the United States of America105(7)2598-603(2008 Feb)
Ignat M,Teletin M,Tisserand J,Khetchoumian K,Dennefeld C,Chambon P,Losson R,Mark M

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Trim24 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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