Sprr1a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Sprr1a
Entrez Gene ID	499660
Full Name	small proline-rich protein 1A
Synonyms	Spr,Spr1a,Sprr,Sprr1,Sprr1al,Sprr1b
General protein information	Preferred Names small proline-rich protein 1A Names cornifin-A small proline-rich protein 1A-like small proline-rich protein 1B (cornifin)
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q34
Summary	precursor protein responsible for crosslinking envelope formation in cells undergoing squamous differentiation [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_021864.1	NP_068636.1	cornifin-A

Pathways from BioSystems

Homologies

Homo sapiens (human)	SPRR1A	NP_005978.2
Mus musculus (house mouse)	Sprr1a	NP_033290.1
Rattus norvegicus (Norway rat)	Sprr1a	NP_068636.1

Gene Ontology
Bibliography

Related articles in PubMed

Selective temporal and regional alterations of Nogo-A and small proline-rich repeat protein 1A (SPRR1A) but not Nogo-66 receptor (NgR) occur following traumatic brain injury in the rat.
Marklund N, Fulp CT, Shimizu S, Puri R, McMillan A, Strittmatter SM, McIntosh TK
Experimental neurology197(1)70-83(2006 Jan)

SPRR1B overexpression enhances entry of cells into the G0 phase of the cell cycle.
Tesfaigzi Y, Wright PS, Belinsky SA
American journal of physiology. Lung cellular and molecular physiology285(4)L889-98(2003 Oct)

Differentially expressed late constituents of the epidermal cornified envelope.
Marshall D, Hardman MJ, Nield KM, Byrne C
Proceedings of the National Academy of Sciences of the United States of America98(23)13031-6(2001 Nov)

Small proline-rich protein 1 is the major component of the cell envelope of normal human oral keratinocytes.
Lee CH, Marekov LN, Kim S, Brahim JS, Park MH, Steinert PM
FEBS letters477(3)268-72(2000 Jul)

A small proline-rich protein, SPRR1, is upregulated early during tobacco smoke-induced squamous metaplasia in rat nasal epithelia.
Tesfaigzi J, Th'ng J, Hotchkiss JA, Harkema JR, Wright PS
American journal of respiratory cell and molecular biology14(5)478-86(1996 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

increases in Nogo-A and SPRR1A in several important brain regions suggest that the injured brain is capable of expressing proteins promoting axonal outgrowth following traumatic brain injury
Title: Selective temporal and regional alterations of Nogo-A and small proline-rich repeat protein 1A (SPRR1A) but not Nogo-66 receptor (NgR) occur following traumatic brain injury in the rat.

SPRR1B expression pattern in nonsquamous tumors; findings indicate SPRR1B likely coupled to signals responsible for withdrawal from the proliferative state; overexpression for prolonged periods may disrupt normal progression of mitosis (sprr1B)
Title: SPRR1B overexpression enhances entry of cells into the G0 phase of the cell cycle.

The following Sprr1a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sprr1a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa05313	NM_021864.1 Latest version!	Rattus norvegicus small proline-rich protein 1A (Sprr1a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Sprr1a ( NM_021864.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_068636.1 Rattus norvegicus small proline-rich protein 1A (Sprr1a), mRNA.

Price & Availability↑

CloneID	ORa05313
Clone ID Related Accession (Same CDS sequence)	NM_021864.1
Accession Version	NM_021864.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 459bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Rattus norvegicus(Norway rat)
Product	cornifin-A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07012305.1. On or before Sep 1, 2012 this sequence version replaced XM_574984.3, XM_001056859.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: FN805093.1, FN805092.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGAGTTCCC ACCAGCAGAA GCAGCCTTGC ACTGTACCCC CTCAGCTGCA CCAGCAGCAG 
GTGAAACAGC CTTGCCAGCC ACCACCCCAG GAACCTTGTG CTCCCAAAAC TAAGGAGCCC 
TGTCACCCTA TTCCTGAGCC CTGCAACCCC AAGGTGCCAG AGCCCTGCCA GCCTAAGGTG 
CCAGAGCCTT GTCAACCTAA GGTGCCAGAG CCTTGCCAGC CTAAGGTGCC AGAGCCTTGC 
CAGCCTAAGG TGCCAGAGCC TTGCCAGCCT AAGGTGCCAG AGCCCTGCCA GCCTAAGGTG 
CCAGAGCCCT GCCATCCCAA GGCACCTGAG CCCTGCCACC CTGTTGTTCC CGAGCCCTGC 
CAGCCTGTTG CTCCTGAGCC CTGCCAGCCT GTTGTTCCTG AACCCTGCCC CCCAACTGTC 
ACTCCATCAC CATACCAGCA GAAGACAAAG CAGAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_068636.1
CDS	49..507
Translation	MSSHQQKQPCTVPPQLHQQQVKQPCQPPPQEPCAPKTKEPCHPIPEPCNPKVPEPCQPKVPEPCQPKVPEPCQPKVPEPCQPKVPEPCQPKVPEPCQPKVPEPCHPKAPEPCHPVVPEPCQPVAPEPCQPVVPEPCPPTVTPSPYQQKTKQK

Target ORF information:

RefSeq Version	NM_021864.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus small proline-rich protein 1A (Sprr1a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021864.1

ORF Insert Sequence:

ATGAGTTCCC ACCAGCAGAA GCAGCCTTGC ACTGTACCCC CTCAGCTGCA CCAGCAGCAG 
GTGAAACAGC CTTGCCAGCC ACCACCCCAG GAACCTTGTG CTCCCAAAAC TAAGGAGCCC 
TGTCACCCTA TTCCTGAGCC CTGCAACCCC AAGGTGCCAG AGCCCTGCCA GCCTAAGGTG 
CCAGAGCCTT GTCAACCTAA GGTGCCAGAG CCTTGCCAGC CTAAGGTGCC AGAGCCTTGC 
CAGCCTAAGG TGCCAGAGCC TTGCCAGCCT AAGGTGCCAG AGCCCTGCCA GCCTAAGGTG 
CCAGAGCCCT GCCATCCCAA GGCACCTGAG CCCTGCCACC CTGTTGTTCC CGAGCCCTGC 
CAGCCTGTTG CTCCTGAGCC CTGCCAGCCT GTTGTTCCTG AACCCTGCCC CCCAACTGTC 
ACTCCATCAC CATACCAGCA GAAGACAAAG CAGAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Selective temporal and regional alterations of Nogo-A and small proline-rich repeat protein 1A (SPRR1A) but not Nogo-66 receptor (NgR) occur following traumatic brain injury in the rat.
Experimental neurology197(1)70-83(2006 Jan)
Marklund N,Fulp CT,Shimizu S,Puri R,McMillan A,Strittmatter SM,McIntosh TK

SPRR1B overexpression enhances entry of cells into the G0 phase of the cell cycle.
American journal of physiology. Lung cellular and molecular physiology285(4)L889-98(2003 Oct)
Tesfaigzi Y,Wright PS,Belinsky SA

Differentially expressed late constituents of the epidermal cornified envelope.
Proceedings of the National Academy of Sciences of the United States of America98(23)13031-6(2001 Nov)
Marshall D,Hardman MJ,Nield KM,Byrne C

Small proline-rich protein 1 is the major component of the cell envelope of normal human oral keratinocytes.
FEBS letters477(3)268-72(2000 Jul)
Lee CH,Marekov LN,Kim S,Brahim JS,Park MH,Steinert PM

A small proline-rich protein, SPRR1, is upregulated early during tobacco smoke-induced squamous metaplasia in rat nasal epithelia.
American journal of respiratory cell and molecular biology14(5)478-86(1996 May)
Tesfaigzi J,Th'ng J,Hotchkiss JA,Harkema JR,Wright PS

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Sprr1a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報