RT1-M5 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	RT1-M5
Entrez Gene ID	499400
Full Name	RT1 class Ib, locus M5
Synonyms	Hla-f,RGD1560260,RT1.M5
General protein information	Preferred Names RT1 class Ib, locus M5 Names RT1 class Ib, locus M5 major histocompatibility complex, class I, F
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 20 Map Location: 20p12

mRNA and Protein(s)

mRNA	Protein	Name
NM_001168353.1	NP_001161825.1	RT1 class Ib, locus M5 isoform 1 precursor
NM_001048045.2	NP_001041510.2	RT1 class Ib, locus M5 isoform 2 precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	H2-M5	NP_001108547.1
Rattus norvegicus (Norway rat)	RT1-M5	NP_001041510.2
Pan troglodytes (chimpanzee)	LOC749652	XP_001170648.2

Gene Ontology
Bibliography

Related articles in PubMed

HLA-B27 subtypes in Turkish patients with ankylosing spondylitis and healthy controls.
Acar M, Cora T, Tunc R, Acar H
Rheumatology international32(10)3103-5(2012 Oct)

Structure and expression of MHC class Ib genes of the central M region in rat and mouse: M4, M5, and M6.
Lambracht-Washington D, Moore YF, Wonigeit K, Lindahl KF
Immunogenetics60(3-4)131-45(2008 Apr)

The genomic sequence and comparative analysis of the rat major histocompatibility complex.
Hurt P, Walter L, Sudbrak R, Klages S, M?ller I, Shiina T, Inoko H, Lehrach H, G?nther E, Reinhardt R, Himmelbauer H
Genome research14(4)631-9(2004 Apr)

Novel HLA B*2714 and B*2708 allele associations in seronegative spondarthritis patients and haemophilia patients with chronic synovitis in India.
Shankarkumar U, Ghosh K, Mohanty D
Tissue antigens62(2)175-8(2003 Aug)

The major histocompatibility complex of the rat (Rattus norvegicus).
G?nther E, Walter L
Immunogenetics53(7)520-42(2001 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following RT1-M5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RT1-M5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa10265	NM_001048045.2 Latest version!	Rattus norvegicus RT1 class Ib, locus M5 (RT1-M5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa41718	NM_001168353.1 Latest version!	Rattus norvegicus RT1 class Ib, locus M5 (RT1-M5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RT1-M5 ( NM_001048045.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001041510.2 Rattus norvegicus RT1 class Ib, locus M5 (RT1-M5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	ORa10265
Clone ID Related Accession (Same CDS sequence)	NM_001048045.2
Accession Version	NM_001048045.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1047bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-28
Organism	Rattus norvegicus(Norway rat)
Product	RT1 class Ib, locus M5 isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX883052.1. On Dec 3, 2009 this sequence version replaced NM_001048045.1. Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region compared to variant 1. The resulting protein (isoform 2) is shorter but has the same N- and C-termini compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGGAAGCT CCGTTTTCTC TGTCCTCCTA CCATTGCTGC TCAGCCGAGC TTGGGCATTG 
AACCAGGTCG GCGCAGGCAT CCATTCCTTG CAGTTTTTTG CCACTGCTGT GACCCAGCCT 
AGTTCGAGGG AGCATTCCTT CATCTTTGTC GGCTTTGTGG ACGACACACA GTTCCTGTGC 
TACAACAATC AGGGGGAAAG TCAGAGAATG GAGCCGCGCG CTCTGTGGGT AAAGAATATG 
GGGCCCGGAT ATTGGGAGCG GCAGACTAGG ATGGTCAAGG ACATTTCCAA GAATTCCCTA 
GTGAACTTGC GGGAGGCCAT GAGTGTCTAC AACCACAGCG AGGATGGCAC TCATGTCTTT 
CAGTGTGTGT CTGGCTGTGA CGTGGGGCCA GATGGACTCT TCCTCCGTGG GCACGAGCAG 
CACGCATACG ACGGCCGCGA CTACCTCGCT CTAAACAAGG ACCTGCACTC CTGGACGGCA 
GGTGACACAG CAGCGCAGAT CACGCGGCGC AAGTGGGAGG AAGCTGGTGT CGCGGAGCAA 
AGGCGAACCT ACCTGAAGGG CGAGTGTGTG GAGTCGCTCC GCACATACCT GGAGATAGGG 
AAGGAGACTC TGCTAGGAGC AGATCCTCCA AAAGCACATG TGACCCATCA CCCCAGCCCT 
GAAGGTGATA ACACCCTGAG GTGCTGGGCC CTGGGCTTCT ACCCTTCTGA CATCACCCTG 
ACCTGGCAGC GGGATGGAGA AGACCTGACC CAGGACATGG AGCTTGTGGA GACAAGACCT 
GGGGGTGATG GAACCTTCCA GAAGTGGGCA GCTGTGGTGG TGCCTTCTGG GGAGGAGCAT 
AGATACACAT GCTGTGTGGA GCATGAGGGG CTAACTGAGC CTCTCCTTCT GAAATGGGAC 
CCTTCTAAGC ACACCATCCC CATCATGGGA ATCACTGCTG GCCTGGTTTT CCTTGGAGTT 
GCCTTCACTG GAGCTGTGGT TGCCATAGCG ATGAGGAAGC AGAGAGCACA TTTGGAAAGA 
AGTGACAAAT ACCTCACATG GACATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001041510.2
CDS	1..1047
Translation	MGSSVFSVLLPLLLSRAWALNQVGAGIHSLQFFATAVTQPSSREHSFIFVGFVDDTQFLCYNNQGESQRMEPRALWVKNMGPGYWERQTRMVKDISKNSLVNLREAMSVYNHSEDGTHVFQCVSGCDVGPDGLFLRGHEQHAYDGRDYLALNKDLHSWTAGDTAAQITRRKWEEAGVAEQRRTYLKGECVESLRTYLEIGKETLLGADPPKAHVTHHPSPEGDNTLRCWALGFYPSDITLTWQRDGEDLTQDMELVETRPGGDGTFQKWAAVVVPSGEEHRYTCCVEHEGLTEPLLLKWDPSKHTIPIMGITAGLVFLGVAFTGAVVAIAMRKQRAHLERSDKYLTWT

Target ORF information:

RefSeq Version	NM_001048045.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus RT1 class Ib, locus M5 (RT1-M5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001048045.2

ORF Insert Sequence:

ATGGGAAGCT CCGTTTTCTC TGTCCTCCTA CCATTGCTGC TCAGCCGAGC TTGGGCATTG 
AACCAGGTCG GCGCAGGCAT CCATTCCTTG CAGTTTTTTG CCACTGCTGT GACCCAGCCT 
AGTTCGAGGG AGCATTCCTT CATCTTTGTC GGCTTTGTGG ACGACACACA GTTCCTGTGC 
TACAACAATC AGGGGGAAAG TCAGAGAATG GAGCCGCGCG CTCTGTGGGT AAAGAATATG 
GGGCCCGGAT ATTGGGAGCG GCAGACTAGG ATGGTCAAGG ACATTTCCAA GAATTCCCTA 
GTGAACTTGC GGGAGGCCAT GAGTGTCTAC AACCACAGCG AGGATGGCAC TCATGTCTTT 
CAGTGTGTGT CTGGCTGTGA CGTGGGGCCA GATGGACTCT TCCTCCGTGG GCACGAGCAG 
CACGCATACG ACGGCCGCGA CTACCTCGCT CTAAACAAGG ACCTGCACTC CTGGACGGCA 
GGTGACACAG CAGCGCAGAT CACGCGGCGC AAGTGGGAGG AAGCTGGTGT CGCGGAGCAA 
AGGCGAACCT ACCTGAAGGG CGAGTGTGTG GAGTCGCTCC GCACATACCT GGAGATAGGG 
AAGGAGACTC TGCTAGGAGC AGATCCTCCA AAAGCACATG TGACCCATCA CCCCAGCCCT 
GAAGGTGATA ACACCCTGAG GTGCTGGGCC CTGGGCTTCT ACCCTTCTGA CATCACCCTG 
ACCTGGCAGC GGGATGGAGA AGACCTGACC CAGGACATGG AGCTTGTGGA GACAAGACCT 
GGGGGTGATG GAACCTTCCA GAAGTGGGCA GCTGTGGTGG TGCCTTCTGG GGAGGAGCAT 
AGATACACAT GCTGTGTGGA GCATGAGGGG CTAACTGAGC CTCTCCTTCT GAAATGGGAC 
CCTTCTAAGC ACACCATCCC CATCATGGGA ATCACTGCTG GCCTGGTTTT CCTTGGAGTT 
GCCTTCACTG GAGCTGTGGT TGCCATAGCG ATGAGGAAGC AGAGAGCACA TTTGGAAAGA 
AGTGACAAAT ACCTCACATG GACATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RT1-M5 ( NM_001168353.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001161825.1 Rattus norvegicus RT1 class Ib, locus M5 (RT1-M5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	ORa41718
Clone ID Related Accession (Same CDS sequence)	NM_001168353.1
Accession Version	NM_001168353.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1074bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-28
Organism	Rattus norvegicus(Norway rat)
Product	RT1 class Ib, locus M5 isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX883052.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGGAAGCT CCGTTTTCTC TGTCCTCCTA CCATTGCTGC TCAGCCGAGC TTGGGCATTG 
AACCAGGTCG GCGCAGGCAT CCATTCCTTG CAGTTTTTTG CCACTGCTGT GACCCAGCCT 
AGTTCGAGGG AGCATTCCTT CATCTTTGTC GGCTTTGTGG ACGACACACA GTTCCTGTGC 
TACAACAATC AGGGGGAAAG TCAGAGAATG GAGCCGCGCG CTCTGTGGGT AAAGAATATG 
GGGCCCGGAT ATTGGGAGCG GCAGACTAGG ATGGTCAAGG ACATTTCCAA GAATTCCCTA 
GTGAACTTGC GGGAGGCCAT GAGTGTCTAC AACCACAGCG AGGATGGCAC TCATGTCTTT 
CAGTGTGTGT CTGGCTGTGA CGTGGGGCCA GATGGACTCT TCCTCCGTGG GCACGAGCAG 
CACGCATACG ACGGCCGCGA CTACCTCGCT CTAAACAAGG ACCTGCACTC CTGGACGGCA 
GGTGACACAG CAGCGCAGAT CACGCGGCGC AAGTGGGAGG AAGCTGGTGT CGCGGAGCAA 
AGGCGAACCT ACCTGAAGGG CGAGTGTGTG GAGTCGCTCC GCACATACCT GGAGATAGGG 
AAGGAGACTC TGCTAGGAGC AGATCCTCCA AAAGCACATG TGACCCATCA CCCCAGCCCT 
GAAGGTGATA ACACCCTGAG GTGCTGGGCC CTGGGCTTCT ACCCTTCTGA CATCACCCTG 
ACCTGGCAGC GGGATGGAGA AGACCTGACC CAGGACATGG AGCTTGTGGA GACAAGACCT 
GGGGGTGATG GAACCTTCCA GAAGTGGGCA GCTGTGGTGG TGCCTTCTGG GGAGGAGCAT 
AGATACACAT GCTGTGTGGA GCATGAGGGG CTAACTGAGC CTCTCCTTCT GAAATGGGAC 
CCTTCTAAGC ACACCATCCC CATCATGGGA ATCACTGCTG GCCTGGTTTT CCTTGGAGTT 
GCCTTCACTG GAGCTGTGGT TGCCATAGCG ATGAGGAAGC AGAGAGGATG TCGTGTTCTA 
ACTCCTTCTA AAGCACATTT GGAAAGAAGT GACAAATACC TCACATGGAC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001161825.1
CDS	1..1074
Translation	MGSSVFSVLLPLLLSRAWALNQVGAGIHSLQFFATAVTQPSSREHSFIFVGFVDDTQFLCYNNQGESQRMEPRALWVKNMGPGYWERQTRMVKDISKNSLVNLREAMSVYNHSEDGTHVFQCVSGCDVGPDGLFLRGHEQHAYDGRDYLALNKDLHSWTAGDTAAQITRRKWEEAGVAEQRRTYLKGECVESLRTYLEIGKETLLGADPPKAHVTHHPSPEGDNTLRCWALGFYPSDITLTWQRDGEDLTQDMELVETRPGGDGTFQKWAAVVVPSGEEHRYTCCVEHEGLTEPLLLKWDPSKHTIPIMGITAGLVFLGVAFTGAVVAIAMRKQRGCRVLTPSKAHLERSDKYLTWT

Target ORF information:

RefSeq Version	NM_001168353.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus RT1 class Ib, locus M5 (RT1-M5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001168353.1

ORF Insert Sequence:

ATGGGAAGCT CCGTTTTCTC TGTCCTCCTA CCATTGCTGC TCAGCCGAGC TTGGGCATTG 
AACCAGGTCG GCGCAGGCAT CCATTCCTTG CAGTTTTTTG CCACTGCTGT GACCCAGCCT 
AGTTCGAGGG AGCATTCCTT CATCTTTGTC GGCTTTGTGG ACGACACACA GTTCCTGTGC 
TACAACAATC AGGGGGAAAG TCAGAGAATG GAGCCGCGCG CTCTGTGGGT AAAGAATATG 
GGGCCCGGAT ATTGGGAGCG GCAGACTAGG ATGGTCAAGG ACATTTCCAA GAATTCCCTA 
GTGAACTTGC GGGAGGCCAT GAGTGTCTAC AACCACAGCG AGGATGGCAC TCATGTCTTT 
CAGTGTGTGT CTGGCTGTGA CGTGGGGCCA GATGGACTCT TCCTCCGTGG GCACGAGCAG 
CACGCATACG ACGGCCGCGA CTACCTCGCT CTAAACAAGG ACCTGCACTC CTGGACGGCA 
GGTGACACAG CAGCGCAGAT CACGCGGCGC AAGTGGGAGG AAGCTGGTGT CGCGGAGCAA 
AGGCGAACCT ACCTGAAGGG CGAGTGTGTG GAGTCGCTCC GCACATACCT GGAGATAGGG 
AAGGAGACTC TGCTAGGAGC AGATCCTCCA AAAGCACATG TGACCCATCA CCCCAGCCCT 
GAAGGTGATA ACACCCTGAG GTGCTGGGCC CTGGGCTTCT ACCCTTCTGA CATCACCCTG 
ACCTGGCAGC GGGATGGAGA AGACCTGACC CAGGACATGG AGCTTGTGGA GACAAGACCT 
GGGGGTGATG GAACCTTCCA GAAGTGGGCA GCTGTGGTGG TGCCTTCTGG GGAGGAGCAT 
AGATACACAT GCTGTGTGGA GCATGAGGGG CTAACTGAGC CTCTCCTTCT GAAATGGGAC 
CCTTCTAAGC ACACCATCCC CATCATGGGA ATCACTGCTG GCCTGGTTTT CCTTGGAGTT 
GCCTTCACTG GAGCTGTGGT TGCCATAGCG ATGAGGAAGC AGAGAGGATG TCGTGTTCTA 
ACTCCTTCTA AAGCACATTT GGAAAGAAGT GACAAATACC TCACATGGAC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

HLA-B27 subtypes in Turkish patients with ankylosing spondylitis and healthy controls.
Rheumatology international32(10)3103-5(2012 Oct)
Acar M,Cora T,Tunc R,Acar H

Structure and expression of MHC class Ib genes of the central M region in rat and mouse: M4, M5, and M6.
Immunogenetics60(3-4)131-45(2008 Apr)
Lambracht-Washington D,Moore YF,Wonigeit K,Lindahl KF

The genomic sequence and comparative analysis of the rat major histocompatibility complex.
Genome research14(4)631-9(2004 Apr)
Hurt P,Walter L,Sudbrak R,Klages S,M?ller I,Shiina T,Inoko H,Lehrach H,G?nther E,Reinhardt R,Himmelbauer H

Novel HLA B*2714 and B*2708 allele associations in seronegative spondarthritis patients and haemophilia patients with chronic synovitis in India.
Tissue antigens62(2)175-8(2003 Aug)
Shankarkumar U,Ghosh K,Mohanty D

The major histocompatibility complex of the rat (Rattus norvegicus).
Immunogenetics53(7)520-42(2001 Sep)
G?nther E,Walter L