Eng cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Eng
Entrez Gene ID	497010
Full Name	endoglin
General protein information	Preferred Names endoglin Names endoglin
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3p11

mRNA and Protein(s)

mRNA	Protein	Name
NM_001010968.2	NP_001010968.1	endoglin precursor
XM_017591971.1	XP_017447460.1	endoglin isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	ENG	NP_001108225.1
Mus musculus (house mouse)	Eng	NP_001139820.1
Pan troglodytes (chimpanzee)	ENG	XP_001143396.3
Gallus gallus (chicken)	ENG	NP_001074356.1
Bos taurus (cattle)	ENG	NP_001069865.1
Rattus norvegicus (Norway rat)	Eng	NP_001010968.1
Xenopus tropicalis (tropical clawed frog)	eng	XP_002935546.2
Canis lupus familiaris (dog)	ENG	XP_851469.2

Gene Ontology
Bibliography

Related articles in PubMed

Intra-Amniotic Soluble Endoglin Impairs Lung Development in Neonatal Rats.
Somashekar ST, Sammour I, Huang J, Dominguez-Bendala J, Pastori R, Alvarez-Cubela S, Torres E, Wu S, Young KC
American journal of respiratory cell and molecular biology57(4)468-476(2017 Oct)

Structural Basis of the Human Endoglin-BMP9 Interaction: Insights into BMP Signaling and HHT1.
Saito T, Bokhove M, Croci R, Zamora-Caballero S, Han L, Letarte M, de Sanctis D, Jovine L
Cell reports19(9)1917-1928(2017 May)

Decreased Endoglin expression in the pulmonary vasculature of nitrofen-induced congenital diaphragmatic hernia rat model.
Zimmer J, Takahashi T, Hofmann AD, Puri P
Pediatric surgery international33(2)263-268(2017 Feb)

Endoglin inhibition leads to intussusceptive angiogenesis via activation of factors related to COUP-TFII signaling pathway.
Hlushchuk R, Styp-Rekowska B, Dzambazi J, Wnuk M, Huynh-Do U, Makanya A, Djonov V
PloS one12(8)e0182813(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

findings demonstrate that intrauterine exposure to an adenovirus overexpressing sENG disrupts lung development by impairing Smad1/5-eNOS signaling. We speculate that sENG-mediated dysregulation of Smad1/5-eNOS signaling contributes to impaired lung development and potentially primes the developing lung for further postnatal insults.
Title: Intra-Amniotic Soluble Endoglin Impairs Lung Development in Neonatal Rats.

Endoglin is expressed mainly by endothelial cells and has been found to be involved in angiogenesis and vascular remodelling.
Title: Decreased Endoglin expression in the pulmonary vasculature of nitrofen-induced congenital diaphragmatic hernia rat model.

In this study, we have shown that ENG inhibition and at the same time up-regulation of COUP-TFII expression promotes intussusceptive angiogenesis.
Title: Endoglin inhibition leads to intussusceptive angiogenesis via activation of factors related to COUP-TFII signaling pathway.

It was confirmed by histopathology and western blotting that COX2 inhibitors, particularly celecoxib, decrease the rate of disease and slow-down progression of existing CRC. These data show that endoglin expression may have an important role in tumor angiogenesis and predict of tumor invasion
Title: Expression of Endoglin and Vascular Endothelial Growth Factor as Prognostic Markers in Experimental Colorectal Cancer.

MicroRNA-208a increases myocardial endoglin expression in acute myocardial infarction.
Title: MicroRNA-208a Increases Myocardial Endoglin Expression and Myocardial Fibrosis in Acute Myocardial Infarction.

The following Eng gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Eng cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01403	NM_001010968.2 Latest version!	Rattus norvegicus endoglin (Eng), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$384.30 $549.00
ORa60504	XM_017591971.1 Latest version!	Rattus norvegicus endoglin (Eng), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Eng ( NM_001010968.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001010968.1 Rattus norvegicus endoglin (Eng), mRNA.

Price & Availability↑

CloneID	ORa01403
Clone ID Related Accession (Same CDS sequence)	NM_001010968.2
Accession Version	NM_001010968.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1953bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-10-20
Organism	Rattus norvegicus(Norway rat)
Product	endoglin precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC105860.1 and AY562420.1. On Oct 18, 2005 this sequence version replaced NM_001010968.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY562420.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGACCGTA GCATGCTCCC TCTGGTCATT ACCCTGCTGT TGGTCATCTA TAGCTTCGTG 
CCCACAAGTC TTGCAGAAAG AGTCGGTTGT GATCTACAGC GTGTGGACTC CACAAGGGGT 
GAGGTGACAT ACACCACCAG CCAGGTCTCT GAGGGCTGTG TAGCTCAGGT TGCCAACGCT 
GCGCATGAAG TCCACGTTCT CTTCCTGAAT CTTTCCAGAA GGAAGTCCGA GGTGGAGTTG 
ACTCTTCAAG CATCCAAGCA AAATGGCACT GAGACTCGGG AGGTGTTTCT GGTCTTCATT 
TCGAACGAGA ATGTCTTGGT GAAGCTCCAG GCCCCAGAAA TCCCACTGCA CTTGGTCTAC 
AACTCCAGCC TCGAGGTCTT CAAAGGACCA AAAGTCAACA GCACACCACT ACCATCCTTT 
ACCTCCAAGA CACAGATCCT CGACTGGGCA GCCACCAAGG GCACCATTAC CTCCATAGCA 
GCACTGGATG ACCCCAAAAG CATTGTCCTC CGGCTGGGCC AAGACCCAAA GGCACCACCC 
TTCTGCTTCC CAGAAGCTCA GAAGGACATG GGCGTCACAC TTGAATGGCA ACCACGAACC 
CAGACACCAG TCCAAGGCTG CCACTTGGAA GGTGTGACTG GACACAAGGA GGCCTATGTC 
CTGAGGATTC GATCAGGTTC TGAGGCCGGG CCCCGGACAG TGACGGTAAC GGTGAAACTG 
AGTTGCACAT CTGGGGATGC CGTTCTCATC CTGCAGGGTC CCCCGTACGT CTCCTGGCTC 
ATCGATACCA ACCACAATAT GCAGATCTGG ACCACAGGTG AATACTCCAT CAAGATCTTT 
CCAGAAAACA ACATCAAAGG CTTCGAGCTC CCAGACACAC CCCAAGGCCT GATCGGGGAG 
GCCCGCAAGC TCAATGCCAG CATAGTAACC TTTGTAGAGA TCCCTCTGAC CAGTGATGTC 
TCCCTGACGG TCTCCAGCTG CGGTGGTGGG CTCCAGACCT CCCCTGCACC AGTTGTGACC 
ACACCTCCCA AGGACACGTG CAGCCCTGAG CTACTCATGT CCCTGATTCA GCCAAAGTGT 
GGCAATGACG TCATGACTCT GGCACTCAAT AAAAAACTCG TGCAGACTCT ACAGTGCACC 
ATCACAGGCC TGGCTTTCTG GGACTCCAGC TGCCAGGCTA AAGACCAGGA CGGCCACCTT 
GTCCTGAGTA GCACCTACTC CAGCTGCGGC ATGAAAGTGA CAGATCATGT GATCAGCAAC 
GAGGTGATCA TCAATTTGCC ATCAGGCTTA CCACCACTTC GGAAAAAGGT ACAGTGCATC 
GACATGGACA GCCTCTCCTT CCAGCTGGGC CTCTACCTCA GCCCGCACTT CCTCCAGGCA 
TCCAACACCA TAGAGCTAGG CCAGCAGGGC TTCGTACAGG TGAGCATGTC TCCATTGACC 
TCTGAGGTCA CAGTCCAGCT AGACAGCTGC CATCTGGATT TGGGGCCAGA AGGTGACATG 
GTGGAACTCA TCCAGAGTCG AGCAGCCAAG GGCAGCTGTG TGAGCTTGCT GTCCCCAAGC 
CCTGAGGGCG ACCCACGTTT CAGCTTTCTC CTCCGTGTCT ACATGGTGCC CACACCCGCA 
GCTGGCACCC TCAGTTGCAA CTTAGCCCTG CACCCTAGCA CCTTGTCCCA GGAAGTCTAC 
AAGACTGTCT CCATGCGCCT GAACATCGTC AGTCCTGACC TGTCTGGCAA AGGCCTCGTC 
CTGCCCTCTG TACTGGGCAT CACCTTTGGT GCCTTCCTCA TTGGGGCCCT GCTCACAGCT 
GCACTCTGGT ACATCTATTC TCACACACGT GCCCCTAGCA AGCGGGAGCC CGTGGTGGCA 
GTGGCTGCCC CGGCCTCCTC TGAGAGCAGC AGTACCAACC ACAGCATCGG GAGCACCCAG 
AGCACCCCCT GCTCCACCAG CAGCATGGCA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001010968.1
CDS	288..2240
Translation	MDRSMLPLVITLLLVIYSFVPTSLAERVGCDLQRVDSTRGEVTYTTSQVSEGCVAQVANAAHEVHVLFLNLSRRKSEVELTLQASKQNGTETREVFLVFISNENVLVKLQAPEIPLHLVYNSSLEVFKGPKVNSTPLPSFTSKTQILDWAATKGTITSIAALDDPKSIVLRLGQDPKAPPFCFPEAQKDMGVTLEWQPRTQTPVQGCHLEGVTGHKEAYVLRIRSGSEAGPRTVTVTVKLSCTSGDAVLILQGPPYVSWLIDTNHNMQIWTTGEYSIKIFPENNIKGFELPDTPQGLIGEARKLNASIVTFVEIPLTSDVSLTVSSCGGGLQTSPAPVVTTPPKDTCSPELLMSLIQPKCGNDVMTLALNKKLVQTLQCTITGLAFWDSSCQAKDQDGHLVLSSTYSSCGMKVTDHVISNEVIINLPSGLPPLRKKVQCIDMDSLSFQLGLYLSPHFLQASNTIELGQQGFVQVSMSPLTSEVTVQLDSCHLDLGPEGDMVELIQSRAAKGSCVSLLSPSPEGDPRFSFLLRVYMVPTPAAGTLSCNLALHPSTLSQEVYKTVSMRLNIVSPDLSGKGLVLPSVLGITFGAFLIGALLTAALWYIYSHTRAPSKREPVVAVAAPASSESSSTNHSIGSTQSTPCSTSSMA

Target ORF information:

RefSeq Version	NM_001010968.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus endoglin (Eng), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001010968.2

ORF Insert Sequence:

ATGGACCGTA GCATGCTCCC TCTGGTCATT ACCCTGCTGT TGGTCATCTA TAGCTTCGTG 
CCCACAAGTC TTGCAGAAAG AGTCGGTTGT GATCTACAGC GTGTGGACTC CACAAGGGGT 
GAGGTGACAT ACACCACCAG CCAGGTCTCT GAGGGCTGTG TAGCTCAGGT TGCCAACGCT 
GCGCATGAAG TCCACGTTCT CTTCCTGAAT CTTTCCAGAA GGAAGTCCGA GGTGGAGTTG 
ACTCTTCAAG CATCCAAGCA AAATGGCACT GAGACTCGGG AGGTGTTTCT GGTCTTCATT 
TCGAACGAGA ATGTCTTGGT GAAGCTCCAG GCCCCAGAAA TCCCACTGCA CTTGGTCTAC 
AACTCCAGCC TCGAGGTCTT CAAAGGACCA AAAGTCAACA GCACACCACT ACCATCCTTT 
ACCTCCAAGA CACAGATCCT CGACTGGGCA GCCACCAAGG GCACCATTAC CTCCATAGCA 
GCACTGGATG ACCCCAAAAG CATTGTCCTC CGGCTGGGCC AAGACCCAAA GGCACCACCC 
TTCTGCTTCC CAGAAGCTCA GAAGGACATG GGCGTCACAC TTGAATGGCA ACCACGAACC 
CAGACACCAG TCCAAGGCTG CCACTTGGAA GGTGTGACTG GACACAAGGA GGCCTATGTC 
CTGAGGATTC GATCAGGTTC TGAGGCCGGG CCCCGGACAG TGACGGTAAC GGTGAAACTG 
AGTTGCACAT CTGGGGATGC CGTTCTCATC CTGCAGGGTC CCCCGTACGT CTCCTGGCTC 
ATCGATACCA ACCACAATAT GCAGATCTGG ACCACAGGTG AATACTCCAT CAAGATCTTT 
CCAGAAAACA ACATCAAAGG CTTCGAGCTC CCAGACACAC CCCAAGGCCT GATCGGGGAG 
GCCCGCAAGC TCAATGCCAG CATAGTAACC TTTGTAGAGA TCCCTCTGAC CAGTGATGTC 
TCCCTGACGG TCTCCAGCTG CGGTGGTGGG CTCCAGACCT CCCCTGCACC AGTTGTGACC 
ACACCTCCCA AGGACACGTG CAGCCCTGAG CTACTCATGT CCCTGATTCA GCCAAAGTGT 
GGCAATGACG TCATGACTCT GGCACTCAAT AAAAAACTCG TGCAGACTCT ACAGTGCACC 
ATCACAGGCC TGGCTTTCTG GGACTCCAGC TGCCAGGCTA AAGACCAGGA CGGCCACCTT 
GTCCTGAGTA GCACCTACTC CAGCTGCGGC ATGAAAGTGA CAGATCATGT GATCAGCAAC 
GAGGTGATCA TCAATTTGCC ATCAGGCTTA CCACCACTTC GGAAAAAGGT ACAGTGCATC 
GACATGGACA GCCTCTCCTT CCAGCTGGGC CTCTACCTCA GCCCGCACTT CCTCCAGGCA 
TCCAACACCA TAGAGCTAGG CCAGCAGGGC TTCGTACAGG TGAGCATGTC TCCATTGACC 
TCTGAGGTCA CAGTCCAGCT AGACAGCTGC CATCTGGATT TGGGGCCAGA AGGTGACATG 
GTGGAACTCA TCCAGAGTCG AGCAGCCAAG GGCAGCTGTG TGAGCTTGCT GTCCCCAAGC 
CCTGAGGGCG ACCCACGTTT CAGCTTTCTC CTCCGTGTCT ACATGGTGCC CACACCCGCA 
GCTGGCACCC TCAGTTGCAA CTTAGCCCTG CACCCTAGCA CCTTGTCCCA GGAAGTCTAC 
AAGACTGTCT CCATGCGCCT GAACATCGTC AGTCCTGACC TGTCTGGCAA AGGCCTCGTC 
CTGCCCTCTG TACTGGGCAT CACCTTTGGT GCCTTCCTCA TTGGGGCCCT GCTCACAGCT 
GCACTCTGGT ACATCTATTC TCACACACGT GCCCCTAGCA AGCGGGAGCC CGTGGTGGCA 
GTGGCTGCCC CGGCCTCCTC TGAGAGCAGC AGTACCAACC ACAGCATCGG GAGCACCCAG 
AGCACCCCCT GCTCCACCAG CAGCATGGCA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Eng ( XM_017591971.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017447460.1 Rattus norvegicus endoglin (Eng), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa60504
Clone ID Related Accession (Same CDS sequence)	XM_017591971.1
Accession Version	XM_017591971.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1641bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	endoglin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END##

ATGGCTGTGC TAGAAGAGGA AGTGACTCAG CACTCTGTGT CTCCACAGAA CTCCAGCCTC 
GAGGTCTTCA AAGGACCAAA AGTCAACAGC ACACCACTAC CATCCTTTAC CTCCAAGACA 
CAGATCCTCG ACTGGGCAGC CACCAAGGGC ACCATTACCT CCATAGCAGC ACTGGATGAC 
CCCAAAAGCA TTGTCCTCCG GCTGGGCCAA GACCCAAAGG CACCACCCTT CTGCTTCCCA 
GAAGCTCAGA AGGACATGGG CGTCACACTT GAATGGCAAC CACGAACCCA GACACCAGTC 
CAAGGCTGCC ACTTGGAAGG TGTGACTGGA CACAAGGAGG CCTATGTCCT GAGGATTCGA 
TCAGGTTCTG AGGCCGGGCC CCGGACAGTG ACGGTAACGG TGAAACTGAG TTGCACATCT 
GGGGATGCCG TTCTCATCCT GCAGGGTCCC CCGTACGTCT CCTGGCTCAT CGATACCAAC 
CACAATATGC AGATCTGGAC CACAGGTGAA TACTCCATCA AGATCTTTCC AGAAAACAAC 
ATCAAAGGCT TCGAGCTCCC AGACACACCC CAAGGCCTGA TCGGGGAGGC CCGCAAGCTC 
AATGCCAGCA TAGTAACCTT TGTAGAGATC CCTCTGACCA GTGATGTCTC CCTGACGGTC 
TCCAGCTGCG GTGGTGGGCT CCAGACCTCC CCTGCACCAG TTGTGACCAC ACCTCCCAAG 
GACACGTGCA GCCCTGAGCT ACTCATGTCC CTGATTCAGC CAAAGTGTGG CAATGACGTC 
ATGACTCTGG CACTCAATAA AAAACTCGTG CAGACTCTAC AGTGCACCAT CACAGGCCTG 
GCTTTCTGGG ACTCCAGCTG CCAGGCTAAA GACCAGGACG GCCACCTTGT CCTGAGTAGC 
ACCTACTCCA GCTGCGGCAT GAAAGTGACA GATCATGTGA TCAGCAACGA GGTGATCATC 
AATTTGCCAT CAGGCTTACC ACCACTTCGG AAAAAGGTAC AGTGCATCGA CATGGACAGC 
CTCTCCTTCC AGCTGGGCCT CTACCTCAGC CCGCACTTCC TCCAGGCATC CAACACCATA 
GAGCTAGGCC AGCAGGGCTT CGTACAGGTG AGCATGTCTC CATTGACCTC TGAGGTCACA 
GTCCAGCTAG ACAGCTGCCA TCTGGATTTG GGGCCAGAAG GTGACATGGT GGAACTCATC 
CAGAGTCGAG CAGCCAAGGG CAGCTGTGTG AGCTTGCTGT CCCCAAGCCC TGAGGGCGAC 
CCACGTTTCA GCTTTCTCCT CCGTGTCTAC ATGGTGCCCA CACCCGCAGC TGGCACCCTC 
AGTTGCAACT TAGCCCTGCA CCCTAGCACC TTGTCCCAGG AAGTCTACAA GACTGTCTCC 
ATGCGCCTGA ACATCGTCAG TCCTGACCTG TCTGGCAAAG GCCTCGTCCT GCCCTCTGTA 
CTGGGCATCA CCTTTGGTGC CTTCCTCATT GGGGCCCTGC TCACAGCTGC ACTCTGGTAC 
ATCTATTCTC ACACACGTGC CCCTAGCAAG CGGGAGCCCG TGGTGGCAGT GGCTGCCCCG 
GCCTCCTCTG AGAGCAGCAG TACCAACCAC AGCATCGGGA GCACCCAGAG CACCCCCTGC 
TCCACCAGCA GCATGGCATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017447460.1
CDS	1..1641
Translation	MAVLEEEVTQHSVSPQNSSLEVFKGPKVNSTPLPSFTSKTQILDWAATKGTITSIAALDDPKSIVLRLGQDPKAPPFCFPEAQKDMGVTLEWQPRTQTPVQGCHLEGVTGHKEAYVLRIRSGSEAGPRTVTVTVKLSCTSGDAVLILQGPPYVSWLIDTNHNMQIWTTGEYSIKIFPENNIKGFELPDTPQGLIGEARKLNASIVTFVEIPLTSDVSLTVSSCGGGLQTSPAPVVTTPPKDTCSPELLMSLIQPKCGNDVMTLALNKKLVQTLQCTITGLAFWDSSCQAKDQDGHLVLSSTYSSCGMKVTDHVISNEVIINLPSGLPPLRKKVQCIDMDSLSFQLGLYLSPHFLQASNTIELGQQGFVQVSMSPLTSEVTVQLDSCHLDLGPEGDMVELIQSRAAKGSCVSLLSPSPEGDPRFSFLLRVYMVPTPAAGTLSCNLALHPSTLSQEVYKTVSMRLNIVSPDLSGKGLVLPSVLGITFGAFLIGALLTAALWYIYSHTRAPSKREPVVAVAAPASSESSSTNHSIGSTQSTPCSTSSMA

Target ORF information:

RefSeq Version	XM_017591971.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus endoglin (Eng), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017591971.1

ORF Insert Sequence:

ATGGCTGTGC TAGAAGAGGA AGTGACTCAG CACTCTGTGT CTCCACAGAA CTCCAGCCTC 
GAGGTCTTCA AAGGACCAAA AGTCAACAGC ACACCACTAC CATCCTTTAC CTCCAAGACA 
CAGATCCTCG ACTGGGCAGC CACCAAGGGC ACCATTACCT CCATAGCAGC ACTGGATGAC 
CCCAAAAGCA TTGTCCTCCG GCTGGGCCAA GACCCAAAGG CACCACCCTT CTGCTTCCCA 
GAAGCTCAGA AGGACATGGG CGTCACACTT GAATGGCAAC CACGAACCCA GACACCAGTC 
CAAGGCTGCC ACTTGGAAGG TGTGACTGGA CACAAGGAGG CCTATGTCCT GAGGATTCGA 
TCAGGTTCTG AGGCCGGGCC CCGGACAGTG ACGGTAACGG TGAAACTGAG TTGCACATCT 
GGGGATGCCG TTCTCATCCT GCAGGGTCCC CCGTACGTCT CCTGGCTCAT CGATACCAAC 
CACAATATGC AGATCTGGAC CACAGGTGAA TACTCCATCA AGATCTTTCC AGAAAACAAC 
ATCAAAGGCT TCGAGCTCCC AGACACACCC CAAGGCCTGA TCGGGGAGGC CCGCAAGCTC 
AATGCCAGCA TAGTAACCTT TGTAGAGATC CCTCTGACCA GTGATGTCTC CCTGACGGTC 
TCCAGCTGCG GTGGTGGGCT CCAGACCTCC CCTGCACCAG TTGTGACCAC ACCTCCCAAG 
GACACGTGCA GCCCTGAGCT ACTCATGTCC CTGATTCAGC CAAAGTGTGG CAATGACGTC 
ATGACTCTGG CACTCAATAA AAAACTCGTG CAGACTCTAC AGTGCACCAT CACAGGCCTG 
GCTTTCTGGG ACTCCAGCTG CCAGGCTAAA GACCAGGACG GCCACCTTGT CCTGAGTAGC 
ACCTACTCCA GCTGCGGCAT GAAAGTGACA GATCATGTGA TCAGCAACGA GGTGATCATC 
AATTTGCCAT CAGGCTTACC ACCACTTCGG AAAAAGGTAC AGTGCATCGA CATGGACAGC 
CTCTCCTTCC AGCTGGGCCT CTACCTCAGC CCGCACTTCC TCCAGGCATC CAACACCATA 
GAGCTAGGCC AGCAGGGCTT CGTACAGGTG AGCATGTCTC CATTGACCTC TGAGGTCACA 
GTCCAGCTAG ACAGCTGCCA TCTGGATTTG GGGCCAGAAG GTGACATGGT GGAACTCATC 
CAGAGTCGAG CAGCCAAGGG CAGCTGTGTG AGCTTGCTGT CCCCAAGCCC TGAGGGCGAC 
CCACGTTTCA GCTTTCTCCT CCGTGTCTAC ATGGTGCCCA CACCCGCAGC TGGCACCCTC 
AGTTGCAACT TAGCCCTGCA CCCTAGCACC TTGTCCCAGG AAGTCTACAA GACTGTCTCC 
ATGCGCCTGA ACATCGTCAG TCCTGACCTG TCTGGCAAAG GCCTCGTCCT GCCCTCTGTA 
CTGGGCATCA CCTTTGGTGC CTTCCTCATT GGGGCCCTGC TCACAGCTGC ACTCTGGTAC 
ATCTATTCTC ACACACGTGC CCCTAGCAAG CGGGAGCCCG TGGTGGCAGT GGCTGCCCCG 
GCCTCCTCTG AGAGCAGCAG TACCAACCAC AGCATCGGGA GCACCCAGAG CACCCCCTGC 
TCCACCAGCA GCATGGCATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Intra-Amniotic Soluble Endoglin Impairs Lung Development in Neonatal Rats.
American journal of respiratory cell and molecular biology57(4)468-476(2017 Oct)
Somashekar ST,Sammour I,Huang J,Dominguez-Bendala J,Pastori R,Alvarez-Cubela S,Torres E,Wu S,Young KC

Structural Basis of the Human Endoglin-BMP9 Interaction: Insights into BMP Signaling and HHT1.
Cell reports19(9)1917-1928(2017 May)
Saito T,Bokhove M,Croci R,Zamora-Caballero S,Han L,Letarte M,de Sanctis D,Jovine L

Decreased Endoglin expression in the pulmonary vasculature of nitrofen-induced congenital diaphragmatic hernia rat model.
Pediatric surgery international33(2)263-268(2017 Feb)
Zimmer J,Takahashi T,Hofmann AD,Puri P

Endoglin inhibition leads to intussusceptive angiogenesis via activation of factors related to COUP-TFII signaling pathway.
PloS one12(8)e0182813(2017)
Hlushchuk R,Styp-Rekowska B,Dzambazi J,Wnuk M,Huynh-Do U,Makanya A,Djonov V

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Eng cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報