Pdcd10 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Pdcd10
Entrez Gene ID	494345
Full Name	programmed cell death 10
General protein information	Preferred Names programmed cell death 10 Names programmed cell death protein 10
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q32

mRNA and Protein(s)

mRNA	Protein	Name
XM_006232501.3	XP_006232563.1	programmed cell death protein 10 isoform X1
NM_001009542.2	NP_001009542.1	programmed cell death protein 10

Pathways from BioSystems

Homologies

Homo sapiens (human)	PDCD10	NP_665858.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008287	XP_001689007.1
Canis lupus familiaris (dog)	PDCD10	XP_545269.1
Pan troglodytes (chimpanzee)	PDCD10	XP_001160479.1
Danio rerio (zebrafish)	pdcd10a	NP_956849.2
Bos taurus (cattle)	PDCD10	NP_001068727.1
Mus musculus (house mouse)	Pdcd10	NP_062719.2
Rattus norvegicus (Norway rat)	Pdcd10	NP_001009542.1
Xenopus tropicalis (tropical clawed frog)	pdcd10	NP_001006850.1
	PDCD10	XP_002802977.1
Gallus gallus (chicken)	PDCD10	NP_001006554.1
Drosophila melanogaster (fruit fly)	CG5073	NP_650459.1
Caenorhabditis elegans (roundworm)	C14A4.11	NP_496290.2

Gene Ontology
Bibliography

Related articles in PubMed

RHO binding to FAM65A regulates Golgi reorientation during cell migration.
Mardakheh FK, Self A, Marshall CJ
Journal of cell science129(24)4466-4479(2016 12)

Structural mechanism of CCM3 heterodimerization with GCKIII kinases.
Zhang M, Dong L, Shi Z, Jiao S, Zhang Z, Zhang W, Liu G, Chen C, Feng M, Hao Q, Wang W, Yin M, Zhao Y, Zhang L, Zhou Z
Structure (London, England : 1993)21(4)680-8(2013 Apr)

Loss of CCM3 impairs DLL4-Notch signalling: implication in endothelial angiogenesis and in inherited cerebral cavernous malformations.
You C, Sandalcioglu IE, Dammann P, Felbor U, Sure U, Zhu Y
Journal of cellular and molecular medicine17(3)407-18(2013 Mar)

Concomitant activation of miR-107/PDCD10 and hypoxamir-210/Casp8ap2 and their role in cytoprotection during ischemic preconditioning of stem cells.
Kim HW, Mallick F, Durrani S, Ashraf M, Jiang S, Haider KH
Antioxidants & redox signaling17(8)1053-65(2012 Oct)

PDCD10 interacts with STK25 to accelerate cell apoptosis under oxidative stress.
Zhang H, Ma X, Deng X, Chen Y, Mo X, Zhang Y, Zhao H, Ma D
Frontiers in bioscience (Landmark edition)172295-305(2012 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The ischemic preconditioning (IPC) enhances stem cell survival via the combined participation of hypoxia responsive miRs miR-107 and miR-210 via their respective putative target genes Pdcd10 and Casp8ap2.
Title: Concomitant activation of miR-107/PDCD10 and hypoxamir-210/Casp8ap2 and their role in cytoprotection during ischemic preconditioning of stem cells.

The following Pdcd10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pdcd10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01169	NM_001009542.2 Latest version!	Rattus norvegicus programmed cell death 10 (Pdcd10), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa01169	XM_006232501.3 Latest version!	Rattus norvegicus programmed cell death 10 (Pdcd10), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Pdcd10 ( NM_001009542.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001009542.1 Rattus norvegicus programmed cell death 10 (Pdcd10), mRNA.

Price & Availability↑

CloneID	ORa01169
Clone ID Related Accession (Same CDS sequence)	XM_006232501.3 , NM_001009542.2
Accession Version	NM_001009542.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 633bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Rattus norvegicus(Norway rat)
Product	programmed cell death protein 10
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC067245.1. On Aug 30, 2012 this sequence version replaced NM_001009542.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC067245.1, FQ213019.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906347, SAMN01906349 [ECO:0000348] ##Evidence-Data-END##

ATGACAATGG AAGAGATGAA GACTGAAGCT GAGGCCGCGT CCATGGTTTC CATGCCTCTC 
TACGCAGTCA TGTACCCTGT GTTTAACGAG CTAGAACGAG TAAATTTGTC TGCAGCTCAG 
ACTCTGAGAG CCGCTTTCAT TAAGGCTGAA AAGGAAAATC CAGGCCTCAC ACAAGACATC 
ATTATGAAAA TCTTAGAGAA AAAAAGTGTA GAAGTTAACT TCACTGAGTC CCTTCTTCGT 
ATGGCAGCTG ATGACGTAGA AGAGTACATG ATTGAACGAC CAGAGCCAGA ATTCCAGGAC 
CTAAATGAAA AGGCACGGGC ACTTAAACAG ATTCTCAGTA AGATTCCAGA CGAGATCAAT 
GACAGAGTGA GGTTTCTGCA GACAATCAAG GATATAGCTA GTGCAATAAA AGAACTACTT 
GATACAGTGA ATAATGTCTT TAAAAAATAT CAATACCAGA ACCGCAGGGC ACTTGAACAC 
CAAAAGAAAG AATTTGTAAA ATACTCCAAA AGTTTCAGTG ACACTCTGAA GACATATTTT 
AAAGATGGCA AGGCAATAAA TGTGTTCATA AGTGCCAACC GGCTAATTCA TCAAACCAAC 
TTGATACTTC AGACCTTCAA AACTGTGGCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001009542.1
CDS	208..840
Translation	MTMEEMKTEAEAASMVSMPLYAVMYPVFNELERVNLSAAQTLRAAFIKAEKENPGLTQDIIMKILEKKSVEVNFTESLLRMAADDVEEYMIERPEPEFQDLNEKARALKQILSKIPDEINDRVRFLQTIKDIASAIKELLDTVNNVFKKYQYQNRRALEHQKKEFVKYSKSFSDTLKTYFKDGKAINVFISANRLIHQTNLILQTFKTVA

Target ORF information:

RefSeq Version	NM_001009542.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus programmed cell death 10 (Pdcd10), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001009542.2

ORF Insert Sequence:

ATGACAATGG AAGAGATGAA GACTGAAGCT GAGGCCGCGT CCATGGTTTC CATGCCTCTC 
TACGCAGTCA TGTACCCTGT GTTTAACGAG CTAGAACGAG TAAATTTGTC TGCAGCTCAG 
ACTCTGAGAG CCGCTTTCAT TAAGGCTGAA AAGGAAAATC CAGGCCTCAC ACAAGACATC 
ATTATGAAAA TCTTAGAGAA AAAAAGTGTA GAAGTTAACT TCACTGAGTC CCTTCTTCGT 
ATGGCAGCTG ATGACGTAGA AGAGTACATG ATTGAACGAC CAGAGCCAGA ATTCCAGGAC 
CTAAATGAAA AGGCACGGGC ACTTAAACAG ATTCTCAGTA AGATTCCAGA CGAGATCAAT 
GACAGAGTGA GGTTTCTGCA GACAATCAAG GATATAGCTA GTGCAATAAA AGAACTACTT 
GATACAGTGA ATAATGTCTT TAAAAAATAT CAATACCAGA ACCGCAGGGC ACTTGAACAC 
CAAAAGAAAG AATTTGTAAA ATACTCCAAA AGTTTCAGTG ACACTCTGAA GACATATTTT 
AAAGATGGCA AGGCAATAAA TGTGTTCATA AGTGCCAACC GGCTAATTCA TCAAACCAAC 
TTGATACTTC AGACCTTCAA AACTGTGGCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Pdcd10 ( XM_006232501.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006232563.1 Rattus norvegicus programmed cell death 10 (Pdcd10), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa01169
Clone ID Related Accession (Same CDS sequence)	XM_006232501.3 , NM_001009542.2
Accession Version	XM_006232501.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 633bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	programmed cell death protein 10 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006232501.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACAATGG AAGAGATGAA GACTGAAGCT GAGGCCGCGT CCATGGTTTC CATGCCTCTC 
TACGCAGTCA TGTACCCTGT GTTTAACGAG CTAGAACGAG TAAATTTGTC TGCAGCTCAG 
ACTCTGAGAG CCGCTTTCAT TAAGGCTGAA AAGGAAAATC CAGGCCTCAC ACAAGACATC 
ATTATGAAAA TCTTAGAGAA AAAAAGTGTA GAAGTTAACT TCACTGAGTC CCTTCTTCGT 
ATGGCAGCTG ATGACGTAGA AGAGTACATG ATTGAACGAC CAGAGCCAGA ATTCCAGGAC 
CTAAATGAAA AGGCACGGGC ACTTAAACAG ATTCTCAGTA AGATTCCAGA CGAGATCAAT 
GACAGAGTGA GGTTTCTGCA GACAATCAAG GATATAGCTA GTGCAATAAA AGAACTACTT 
GATACAGTGA ATAATGTCTT TAAAAAATAT CAATACCAGA ACCGCAGGGC ACTTGAACAC 
CAAAAGAAAG AATTTGTAAA ATACTCCAAA AGTTTCAGTG ACACTCTGAA GACATATTTT 
AAAGATGGCA AGGCAATAAA TGTGTTCATA AGTGCCAACC GGCTAATTCA TCAAACCAAC 
TTGATACTTC AGACCTTCAA AACTGTGGCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006232563.1
CDS	170..802
Translation	MTMEEMKTEAEAASMVSMPLYAVMYPVFNELERVNLSAAQTLRAAFIKAEKENPGLTQDIIMKILEKKSVEVNFTESLLRMAADDVEEYMIERPEPEFQDLNEKARALKQILSKIPDEINDRVRFLQTIKDIASAIKELLDTVNNVFKKYQYQNRRALEHQKKEFVKYSKSFSDTLKTYFKDGKAINVFISANRLIHQTNLILQTFKTVA

Target ORF information:

RefSeq Version	XM_006232501.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus programmed cell death 10 (Pdcd10), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006232501.3

ORF Insert Sequence:

ATGACAATGG AAGAGATGAA GACTGAAGCT GAGGCCGCGT CCATGGTTTC CATGCCTCTC 
TACGCAGTCA TGTACCCTGT GTTTAACGAG CTAGAACGAG TAAATTTGTC TGCAGCTCAG 
ACTCTGAGAG CCGCTTTCAT TAAGGCTGAA AAGGAAAATC CAGGCCTCAC ACAAGACATC 
ATTATGAAAA TCTTAGAGAA AAAAAGTGTA GAAGTTAACT TCACTGAGTC CCTTCTTCGT 
ATGGCAGCTG ATGACGTAGA AGAGTACATG ATTGAACGAC CAGAGCCAGA ATTCCAGGAC 
CTAAATGAAA AGGCACGGGC ACTTAAACAG ATTCTCAGTA AGATTCCAGA CGAGATCAAT 
GACAGAGTGA GGTTTCTGCA GACAATCAAG GATATAGCTA GTGCAATAAA AGAACTACTT 
GATACAGTGA ATAATGTCTT TAAAAAATAT CAATACCAGA ACCGCAGGGC ACTTGAACAC 
CAAAAGAAAG AATTTGTAAA ATACTCCAAA AGTTTCAGTG ACACTCTGAA GACATATTTT 
AAAGATGGCA AGGCAATAAA TGTGTTCATA AGTGCCAACC GGCTAATTCA TCAAACCAAC 
TTGATACTTC AGACCTTCAA AACTGTGGCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

RHO binding to FAM65A regulates Golgi reorientation during cell migration.
Journal of cell science129(24)4466-4479(2016 12)
Mardakheh FK,Self A,Marshall CJ

Structural mechanism of CCM3 heterodimerization with GCKIII kinases.
Structure (London, England : 1993)21(4)680-8(2013 Apr)
Zhang M,Dong L,Shi Z,Jiao S,Zhang Z,Zhang W,Liu G,Chen C,Feng M,Hao Q,Wang W,Yin M,Zhao Y,Zhang L,Zhou Z

Loss of CCM3 impairs DLL4-Notch signalling: implication in endothelial angiogenesis and in inherited cerebral cavernous malformations.
Journal of cellular and molecular medicine17(3)407-18(2013 Mar)
You C,Sandalcioglu IE,Dammann P,Felbor U,Sure U,Zhu Y

Concomitant activation of miR-107/PDCD10 and hypoxamir-210/Casp8ap2 and their role in cytoprotection during ischemic preconditioning of stem cells.
Antioxidants & redox signaling17(8)1053-65(2012 Oct)
Kim HW,Mallick F,Durrani S,Ashraf M,Jiang S,Haider KH

PDCD10 interacts with STK25 to accelerate cell apoptosis under oxidative stress.
Frontiers in bioscience (Landmark edition)172295-305(2012 Jun)
Zhang H,Ma X,Deng X,Chen Y,Mo X,Zhang Y,Zhao H,Ma D