Bag5 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Bag5
Entrez Gene ID	366734
Full Name	BCL2-associated athanogene 5
General protein information	Preferred Names BCL2-associated athanogene 5 Names BAG family molecular chaperone regulator 5 BAG-5 bcl-2-associated athanogene 5
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 6 Map Location: 6q32

mRNA and Protein(s)

mRNA	Protein	Name
XM_006240601.2	XP_006240663.1	BAG family molecular chaperone regulator 5 isoform X1
XM_006240602.2	XP_006240664.1	BAG family molecular chaperone regulator 5 isoform X1
XM_006240603.3	XP_006240665.1	BAG family molecular chaperone regulator 5 isoform X1
NM_001008526.2	NP_001008526.1	BAG family molecular chaperone regulator 5

Pathways from BioSystems

Homologies

Bos taurus (cattle)	BAG5	NP_001035634.1
Gallus gallus (chicken)	BAG5	NP_001026382.1
Xenopus tropicalis (tropical clawed frog)	bag5	NP_001124516.1
Pan troglodytes (chimpanzee)	BAG5	NP_001233383.1
Mus musculus (house mouse)	Bag5	NP_081680.1
Rattus norvegicus (Norway rat)	Bag5	NP_001008526.1
Homo sapiens (human)	BAG5	NP_001015049.1
Danio rerio (zebrafish)	bag5	NP_001029355.1
	BAG5	XP_002805271.1
Canis lupus familiaris (dog)	BAG5	XP_005623904.1

Gene Ontology
Bibliography

Related articles in PubMed

GRP78 Interacting Partner Bag5 Responds to ER Stress and Protects Cardiomyocytes From ER Stress-Induced Apoptosis.
Gupta MK, Tahrir FG, Knezevic T, White MK, Gordon J, Cheung JY, Khalili K, Feldman AM
Journal of cellular biochemistry117(8)1813-21(2016 08)

The BAG2 and BAG5 proteins inhibit the ubiquitination of pathogenic ataxin3-80Q.
Che XQ, Tang BS, Wang HF, Yan XX, Jiang H, Shen L, Xu Q, Wang GH, Zhang HN, Wang CY, Guo JF
The International journal of neuroscience125(5)390-4(2015 May)

Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease.
Beilina A, Rudenko IN, Kaganovich A, Civiero L, Chau H, Kalia SK, Kalia LV, Lobbestael E, Chia R, Ndukwe K, Ding J, Nalls MA, , , Olszewski M, Hauser DN, Kumaran R, Lozano AM, Baekelandt V, Greene LE, Taymans JM, Greggio E, Cookson MR
Proceedings of the National Academy of Sciences of the United States of America111(7)2626-31(2014 Feb)

BAG5 protects against mitochondrial oxidative damage through regulating PINK1 degradation.
Wang X, Guo J, Fei E, Mu Y, He S, Che X, Tan J, Xia K, Zhang Z, Wang G, Tang B
PloS one9(1)e86276(2014)

High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy.
Hasson SA, Kane LA, Yamano K, Huang CH, Sliter DA, Buehler E, Wang C, Heman-Ackah SM, Hessa T, Guha R, Martin SE, Youle RJ
Nature504(7479)291-5(2013 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Bag5 protein expression is significantly increased in the ER during ER stress and that this in turn modulates GRP78 protein stability and reduces ER stress.
Title: GRP78 Interacting Partner Bag5 Responds to ER Stress and Protects Cardiomyocytes From ER Stress-Induced Apoptosis.

BAG5 induction inhibits MPP(+)-induced apoptosis through both endogenous and mitochondria-mediated pathways of apoptosis.
Title: Protective effect of BAG5 on MPP+-induced apoptosis in PC12 cells.

BAG5 enhances dopamine neuron death in a rat model of Parkinson's disease, whereas a mutant that inhibits BAG5 activity attenuates dopaminergic neurodegeneration.
Title: BAG5 inhibits parkin and enhances dopaminergic neuron degeneration.

The following Bag5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Bag5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa12465	NM_001008526.2 Latest version!	Rattus norvegicus BAG cochaperone 5 (Bag5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa12465	XM_006240602.2 Latest version!	Rattus norvegicus BCL2-associated athanogene 5 (Bag5), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa12465	XM_006240603.3 Latest version!	Rattus norvegicus BCL2-associated athanogene 5 (Bag5), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa12465	XM_006240601.2 Latest version!	Rattus norvegicus BCL2-associated athanogene 5 (Bag5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Bag5 ( NM_001008526.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001008526.1 Rattus norvegicus BAG cochaperone 5 (Bag5), mRNA.

Price & Availability↑

CloneID	ORa12465
Clone ID Related Accession (Same CDS sequence)	XM_006240601.2 , XM_006240602.2 , XM_006240603.3 , NM_001008526.2
Accession Version	NM_001008526.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1344bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-19
Organism	Rattus norvegicus(Norway rat)
Product	BAG family molecular chaperone regulator 5
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC088418.1. On Jan 2, 2005 this sequence version replaced NM_001008526.1. ##Evidence-Data-START## Transcript exon combination :: BC088418.1, AY366364.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906357 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END##

ATGGATATGG GAAACCAACA CCCTTCTATT AGTAGGCTTC AGGAGATCCA ACGGGAAGTA 
AAGAGTATAG AGCAGCAAGT GGTTGGCTTC AGTGGCCTGT CGGATGACAA GAATTACAAG 
AGACTGGAGA GGATTCTGAC GAAACAACTT TTTGAAATCG ACTCTGTGGA TACAGAAGGG 
AAAGGAGACA TCCAGCAAGC TAGGAAGAGG GCAGCACAGG ACACAGAACG CCTTCTCAAA 
GAGTTGGAGC AGAACGCGAA CCACCCACAC CGGATTGAAA TCAAGAATAT CTTTCAAGAA 
GCTCAGGCCC TTGTGAAAGA AAAGACTGTG CCCTTTTACA GTGGAAGCAA CTGTGTGACT 
AGCGAGTTTG AGGAAGCCAT CCAGGACATC ATTCTGAGGC TGACACATGT TAAAACAGGA 
GGGAAGATCT CCTTGCGGAA AGCAAGGTAC CACACACTAA CCAAGATCTG TGCGGTACAA 
GAGATTATTG AAGACTGTGT GAGGAAACAG CCTTCCCTGC CACTTTCCGA GGATGTGCAT 
CCTTCTGTCG CCAAGATCAA TTCTGTGATG TGTGAGGTGA ACAAGGCCAG AGGTACTCTG 
ATTGCACTTC TGATGGGCGT GGACAGTTCT GAGACTTGCA GGCACTTATC ATGCGTGCTG 
TCAGGACTGA TGGCTGATTT AGATGCTCTA GATGTGTGTG GGCGTACAGA GATCAGAAAT 
TATCGGAGGG AGGTGGTGGA AGATATCAAC AAATTACTAA AATATCTAGA TTTAGAAGAG 
GAAGCTGACA ATACACATGC ATTTGACCTG GGACAGAACC ATTCCATTAT AAAGATAGAA 
AATGTCCTCA AGAGGATGAG AGAAATGAAA AATGAACTTC TCCAGGCACA GAGCCCTCCT 
GAATTGTACC TGAGGTCCAA GACAGAGCTG CAGGGCTTGA TCGGGCAGCT GGACGAAGTG 
AGTCTGGAGA AAAACCCCTG CATCAGAGAG GCCAGGAGAA GAGCAGTGAT TGAGGTGCAG 
ACCCTCATCA CGTACCTGGA CCTGAAGGAG GCCCTCGAGA AGAGGAAGCT GTTCCCGTGT 
GAGGAGACCC CCCCACATAA GGCTGTGTGG AATGTCCTTG GAAACCTGTC AGAGATCCAG 
GGTGAAGTCC TCTCCTTTGG TGGGAACCGA ACTGATAAGA ACTACATTCG TCTGGAGGAG 
CTACTGACCA AACAGTTGCT GACTCTGGAT GCTGTTGACC CACTGGGAGA AGAGAAGTGT 
AAGGCTGCCA GGAAGCAGGC CGTGAAGCTG GCCCAGAACA TCCTCAGCTA CCTTGACATG 
AAGTCTGATG AGTGGGAGTA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001008526.1
CDS	138..1481
Translation	MDMGNQHPSISRLQEIQREVKSIEQQVVGFSGLSDDKNYKRLERILTKQLFEIDSVDTEGKGDIQQARKRAAQDTERLLKELEQNANHPHRIEIKNIFQEAQALVKEKTVPFYSGSNCVTSEFEEAIQDIILRLTHVKTGGKISLRKARYHTLTKICAVQEIIEDCVRKQPSLPLSEDVHPSVAKINSVMCEVNKARGTLIALLMGVDSSETCRHLSCVLSGLMADLDALDVCGRTEIRNYRREVVEDINKLLKYLDLEEEADNTHAFDLGQNHSIIKIENVLKRMREMKNELLQAQSPPELYLRSKTELQGLIGQLDEVSLEKNPCIREARRRAVIEVQTLITYLDLKEALEKRKLFPCEETPPHKAVWNVLGNLSEIQGEVLSFGGNRTDKNYIRLEELLTKQLLTLDAVDPLGEEKCKAARKQAVKLAQNILSYLDMKSDEWEY

Target ORF information:

RefSeq Version	NM_001008526.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus BAG cochaperone 5 (Bag5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001008526.2

ORF Insert Sequence:

ATGGATATGG GAAACCAACA CCCTTCTATT AGTAGGCTTC AGGAGATCCA ACGGGAAGTA 
AAGAGTATAG AGCAGCAAGT GGTTGGCTTC AGTGGCCTGT CGGATGACAA GAATTACAAG 
AGACTGGAGA GGATTCTGAC GAAACAACTT TTTGAAATCG ACTCTGTGGA TACAGAAGGG 
AAAGGAGACA TCCAGCAAGC TAGGAAGAGG GCAGCACAGG ACACAGAACG CCTTCTCAAA 
GAGTTGGAGC AGAACGCGAA CCACCCACAC CGGATTGAAA TCAAGAATAT CTTTCAAGAA 
GCTCAGGCCC TTGTGAAAGA AAAGACTGTG CCCTTTTACA GTGGAAGCAA CTGTGTGACT 
AGCGAGTTTG AGGAAGCCAT CCAGGACATC ATTCTGAGGC TGACACATGT TAAAACAGGA 
GGGAAGATCT CCTTGCGGAA AGCAAGGTAC CACACACTAA CCAAGATCTG TGCGGTACAA 
GAGATTATTG AAGACTGTGT GAGGAAACAG CCTTCCCTGC CACTTTCCGA GGATGTGCAT 
CCTTCTGTCG CCAAGATCAA TTCTGTGATG TGTGAGGTGA ACAAGGCCAG AGGTACTCTG 
ATTGCACTTC TGATGGGCGT GGACAGTTCT GAGACTTGCA GGCACTTATC ATGCGTGCTG 
TCAGGACTGA TGGCTGATTT AGATGCTCTA GATGTGTGTG GGCGTACAGA GATCAGAAAT 
TATCGGAGGG AGGTGGTGGA AGATATCAAC AAATTACTAA AATATCTAGA TTTAGAAGAG 
GAAGCTGACA ATACACATGC ATTTGACCTG GGACAGAACC ATTCCATTAT AAAGATAGAA 
AATGTCCTCA AGAGGATGAG AGAAATGAAA AATGAACTTC TCCAGGCACA GAGCCCTCCT 
GAATTGTACC TGAGGTCCAA GACAGAGCTG CAGGGCTTGA TCGGGCAGCT GGACGAAGTG 
AGTCTGGAGA AAAACCCCTG CATCAGAGAG GCCAGGAGAA GAGCAGTGAT TGAGGTGCAG 
ACCCTCATCA CGTACCTGGA CCTGAAGGAG GCCCTCGAGA AGAGGAAGCT GTTCCCGTGT 
GAGGAGACCC CCCCACATAA GGCTGTGTGG AATGTCCTTG GAAACCTGTC AGAGATCCAG 
GGTGAAGTCC TCTCCTTTGG TGGGAACCGA ACTGATAAGA ACTACATTCG TCTGGAGGAG 
CTACTGACCA AACAGTTGCT GACTCTGGAT GCTGTTGACC CACTGGGAGA AGAGAAGTGT 
AAGGCTGCCA GGAAGCAGGC CGTGAAGCTG GCCCAGAACA TCCTCAGCTA CCTTGACATG 
AAGTCTGATG AGTGGGAGTA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Bag5 ( XM_006240601.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006240663.1 Rattus norvegicus BCL2-associated athanogene 5 (Bag5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa12465
Clone ID Related Accession (Same CDS sequence)	XM_006240601.2 , XM_006240602.2 , XM_006240603.3 , NM_001008526.2
Accession Version	XM_006240601.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1344bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	BAG family molecular chaperone regulator 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005105.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006240601.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATATGG GAAACCAACA CCCTTCTATT AGTAGGCTTC AGGAGATCCA ACGGGAAGTA 
AAGAGTATAG AGCAGCAAGT GGTTGGCTTC AGTGGCCTGT CGGATGACAA GAATTACAAG 
AGACTGGAGA GGATTCTGAC GAAACAACTT TTTGAAATCG ACTCTGTGGA TACAGAAGGG 
AAAGGAGACA TCCAGCAAGC TAGGAAGAGG GCAGCACAGG ACACAGAACG CCTTCTCAAA 
GAGTTGGAGC AGAACGCGAA CCACCCACAC CGGATTGAAA TCAAGAATAT CTTTCAAGAA 
GCTCAGGCCC TTGTGAAAGA AAAGACTGTG CCCTTTTACA GTGGAAGCAA CTGTGTGACT 
AGCGAGTTTG AGGAAGCCAT CCAGGACATC ATTCTGAGGC TGACACATGT TAAAACAGGA 
GGGAAGATCT CCTTGCGGAA AGCAAGGTAC CACACACTAA CCAAGATCTG TGCGGTACAA 
GAGATTATTG AAGACTGTGT GAGGAAACAG CCTTCCCTGC CACTTTCCGA GGATGTGCAT 
CCTTCTGTCG CCAAGATCAA TTCTGTGATG TGTGAGGTGA ACAAGGCCAG AGGTACTCTG 
ATTGCACTTC TGATGGGCGT GGACAGTTCT GAGACTTGCA GGCACTTATC ATGCGTGCTG 
TCAGGACTGA TGGCTGATTT AGATGCTCTA GATGTGTGTG GGCGTACAGA GATCAGAAAT 
TATCGGAGGG AGGTGGTGGA AGATATCAAC AAATTACTAA AATATCTAGA TTTAGAAGAG 
GAAGCTGACA ATACACATGC ATTTGACCTG GGACAGAACC ATTCCATTAT AAAGATAGAA 
AATGTCCTCA AGAGGATGAG AGAAATGAAA AATGAACTTC TCCAGGCACA GAGCCCTCCT 
GAATTGTACC TGAGGTCCAA GACAGAGCTG CAGGGCTTGA TCGGGCAGCT GGACGAAGTG 
AGTCTGGAGA AAAACCCCTG CATCAGAGAG GCCAGGAGAA GAGCAGTGAT TGAGGTGCAG 
ACCCTCATCA CGTACCTGGA CCTGAAGGAG GCCCTCGAGA AGAGGAAGCT GTTCCCGTGT 
GAGGAGACCC CCCCACATAA GGCTGTGTGG AATGTCCTTG GAAACCTGTC AGAGATCCAG 
GGTGAAGTCC TCTCCTTTGG TGGGAACCGA ACTGATAAGA ACTACATTCG TCTGGAGGAG 
CTACTGACCA AACAGTTGCT GACTCTGGAT GCTGTTGACC CACTGGGAGA AGAGAAGTGT 
AAGGCTGCCA GGAAGCAGGC CGTGAAGCTG GCCCAGAACA TCCTCAGCTA CCTTGACATG 
AAGTCTGATG AGTGGGAGTA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006240663.1
CDS	298..1641
Translation	MDMGNQHPSISRLQEIQREVKSIEQQVVGFSGLSDDKNYKRLERILTKQLFEIDSVDTEGKGDIQQARKRAAQDTERLLKELEQNANHPHRIEIKNIFQEAQALVKEKTVPFYSGSNCVTSEFEEAIQDIILRLTHVKTGGKISLRKARYHTLTKICAVQEIIEDCVRKQPSLPLSEDVHPSVAKINSVMCEVNKARGTLIALLMGVDSSETCRHLSCVLSGLMADLDALDVCGRTEIRNYRREVVEDINKLLKYLDLEEEADNTHAFDLGQNHSIIKIENVLKRMREMKNELLQAQSPPELYLRSKTELQGLIGQLDEVSLEKNPCIREARRRAVIEVQTLITYLDLKEALEKRKLFPCEETPPHKAVWNVLGNLSEIQGEVLSFGGNRTDKNYIRLEELLTKQLLTLDAVDPLGEEKCKAARKQAVKLAQNILSYLDMKSDEWEY

Target ORF information:

RefSeq Version	XM_006240601.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus BCL2-associated athanogene 5 (Bag5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006240601.2

ORF Insert Sequence:

ATGGATATGG GAAACCAACA CCCTTCTATT AGTAGGCTTC AGGAGATCCA ACGGGAAGTA 
AAGAGTATAG AGCAGCAAGT GGTTGGCTTC AGTGGCCTGT CGGATGACAA GAATTACAAG 
AGACTGGAGA GGATTCTGAC GAAACAACTT TTTGAAATCG ACTCTGTGGA TACAGAAGGG 
AAAGGAGACA TCCAGCAAGC TAGGAAGAGG GCAGCACAGG ACACAGAACG CCTTCTCAAA 
GAGTTGGAGC AGAACGCGAA CCACCCACAC CGGATTGAAA TCAAGAATAT CTTTCAAGAA 
GCTCAGGCCC TTGTGAAAGA AAAGACTGTG CCCTTTTACA GTGGAAGCAA CTGTGTGACT 
AGCGAGTTTG AGGAAGCCAT CCAGGACATC ATTCTGAGGC TGACACATGT TAAAACAGGA 
GGGAAGATCT CCTTGCGGAA AGCAAGGTAC CACACACTAA CCAAGATCTG TGCGGTACAA 
GAGATTATTG AAGACTGTGT GAGGAAACAG CCTTCCCTGC CACTTTCCGA GGATGTGCAT 
CCTTCTGTCG CCAAGATCAA TTCTGTGATG TGTGAGGTGA ACAAGGCCAG AGGTACTCTG 
ATTGCACTTC TGATGGGCGT GGACAGTTCT GAGACTTGCA GGCACTTATC ATGCGTGCTG 
TCAGGACTGA TGGCTGATTT AGATGCTCTA GATGTGTGTG GGCGTACAGA GATCAGAAAT 
TATCGGAGGG AGGTGGTGGA AGATATCAAC AAATTACTAA AATATCTAGA TTTAGAAGAG 
GAAGCTGACA ATACACATGC ATTTGACCTG GGACAGAACC ATTCCATTAT AAAGATAGAA 
AATGTCCTCA AGAGGATGAG AGAAATGAAA AATGAACTTC TCCAGGCACA GAGCCCTCCT 
GAATTGTACC TGAGGTCCAA GACAGAGCTG CAGGGCTTGA TCGGGCAGCT GGACGAAGTG 
AGTCTGGAGA AAAACCCCTG CATCAGAGAG GCCAGGAGAA GAGCAGTGAT TGAGGTGCAG 
ACCCTCATCA CGTACCTGGA CCTGAAGGAG GCCCTCGAGA AGAGGAAGCT GTTCCCGTGT 
GAGGAGACCC CCCCACATAA GGCTGTGTGG AATGTCCTTG GAAACCTGTC AGAGATCCAG 
GGTGAAGTCC TCTCCTTTGG TGGGAACCGA ACTGATAAGA ACTACATTCG TCTGGAGGAG 
CTACTGACCA AACAGTTGCT GACTCTGGAT GCTGTTGACC CACTGGGAGA AGAGAAGTGT 
AAGGCTGCCA GGAAGCAGGC CGTGAAGCTG GCCCAGAACA TCCTCAGCTA CCTTGACATG 
AAGTCTGATG AGTGGGAGTA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Bag5 ( XM_006240602.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006240664.1 Rattus norvegicus BCL2-associated athanogene 5 (Bag5), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa12465
Clone ID Related Accession (Same CDS sequence)	XM_006240601.2 , XM_006240602.2 , XM_006240603.3 , NM_001008526.2
Accession Version	XM_006240602.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1344bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	BAG family molecular chaperone regulator 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005105.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006240602.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATATGG GAAACCAACA CCCTTCTATT AGTAGGCTTC AGGAGATCCA ACGGGAAGTA 
AAGAGTATAG AGCAGCAAGT GGTTGGCTTC AGTGGCCTGT CGGATGACAA GAATTACAAG 
AGACTGGAGA GGATTCTGAC GAAACAACTT TTTGAAATCG ACTCTGTGGA TACAGAAGGG 
AAAGGAGACA TCCAGCAAGC TAGGAAGAGG GCAGCACAGG ACACAGAACG CCTTCTCAAA 
GAGTTGGAGC AGAACGCGAA CCACCCACAC CGGATTGAAA TCAAGAATAT CTTTCAAGAA 
GCTCAGGCCC TTGTGAAAGA AAAGACTGTG CCCTTTTACA GTGGAAGCAA CTGTGTGACT 
AGCGAGTTTG AGGAAGCCAT CCAGGACATC ATTCTGAGGC TGACACATGT TAAAACAGGA 
GGGAAGATCT CCTTGCGGAA AGCAAGGTAC CACACACTAA CCAAGATCTG TGCGGTACAA 
GAGATTATTG AAGACTGTGT GAGGAAACAG CCTTCCCTGC CACTTTCCGA GGATGTGCAT 
CCTTCTGTCG CCAAGATCAA TTCTGTGATG TGTGAGGTGA ACAAGGCCAG AGGTACTCTG 
ATTGCACTTC TGATGGGCGT GGACAGTTCT GAGACTTGCA GGCACTTATC ATGCGTGCTG 
TCAGGACTGA TGGCTGATTT AGATGCTCTA GATGTGTGTG GGCGTACAGA GATCAGAAAT 
TATCGGAGGG AGGTGGTGGA AGATATCAAC AAATTACTAA AATATCTAGA TTTAGAAGAG 
GAAGCTGACA ATACACATGC ATTTGACCTG GGACAGAACC ATTCCATTAT AAAGATAGAA 
AATGTCCTCA AGAGGATGAG AGAAATGAAA AATGAACTTC TCCAGGCACA GAGCCCTCCT 
GAATTGTACC TGAGGTCCAA GACAGAGCTG CAGGGCTTGA TCGGGCAGCT GGACGAAGTG 
AGTCTGGAGA AAAACCCCTG CATCAGAGAG GCCAGGAGAA GAGCAGTGAT TGAGGTGCAG 
ACCCTCATCA CGTACCTGGA CCTGAAGGAG GCCCTCGAGA AGAGGAAGCT GTTCCCGTGT 
GAGGAGACCC CCCCACATAA GGCTGTGTGG AATGTCCTTG GAAACCTGTC AGAGATCCAG 
GGTGAAGTCC TCTCCTTTGG TGGGAACCGA ACTGATAAGA ACTACATTCG TCTGGAGGAG 
CTACTGACCA AACAGTTGCT GACTCTGGAT GCTGTTGACC CACTGGGAGA AGAGAAGTGT 
AAGGCTGCCA GGAAGCAGGC CGTGAAGCTG GCCCAGAACA TCCTCAGCTA CCTTGACATG 
AAGTCTGATG AGTGGGAGTA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006240664.1
CDS	238..1581
Translation	MDMGNQHPSISRLQEIQREVKSIEQQVVGFSGLSDDKNYKRLERILTKQLFEIDSVDTEGKGDIQQARKRAAQDTERLLKELEQNANHPHRIEIKNIFQEAQALVKEKTVPFYSGSNCVTSEFEEAIQDIILRLTHVKTGGKISLRKARYHTLTKICAVQEIIEDCVRKQPSLPLSEDVHPSVAKINSVMCEVNKARGTLIALLMGVDSSETCRHLSCVLSGLMADLDALDVCGRTEIRNYRREVVEDINKLLKYLDLEEEADNTHAFDLGQNHSIIKIENVLKRMREMKNELLQAQSPPELYLRSKTELQGLIGQLDEVSLEKNPCIREARRRAVIEVQTLITYLDLKEALEKRKLFPCEETPPHKAVWNVLGNLSEIQGEVLSFGGNRTDKNYIRLEELLTKQLLTLDAVDPLGEEKCKAARKQAVKLAQNILSYLDMKSDEWEY

Target ORF information:

RefSeq Version	XM_006240602.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus BCL2-associated athanogene 5 (Bag5), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006240602.2

ORF Insert Sequence:

ATGGATATGG GAAACCAACA CCCTTCTATT AGTAGGCTTC AGGAGATCCA ACGGGAAGTA 
AAGAGTATAG AGCAGCAAGT GGTTGGCTTC AGTGGCCTGT CGGATGACAA GAATTACAAG 
AGACTGGAGA GGATTCTGAC GAAACAACTT TTTGAAATCG ACTCTGTGGA TACAGAAGGG 
AAAGGAGACA TCCAGCAAGC TAGGAAGAGG GCAGCACAGG ACACAGAACG CCTTCTCAAA 
GAGTTGGAGC AGAACGCGAA CCACCCACAC CGGATTGAAA TCAAGAATAT CTTTCAAGAA 
GCTCAGGCCC TTGTGAAAGA AAAGACTGTG CCCTTTTACA GTGGAAGCAA CTGTGTGACT 
AGCGAGTTTG AGGAAGCCAT CCAGGACATC ATTCTGAGGC TGACACATGT TAAAACAGGA 
GGGAAGATCT CCTTGCGGAA AGCAAGGTAC CACACACTAA CCAAGATCTG TGCGGTACAA 
GAGATTATTG AAGACTGTGT GAGGAAACAG CCTTCCCTGC CACTTTCCGA GGATGTGCAT 
CCTTCTGTCG CCAAGATCAA TTCTGTGATG TGTGAGGTGA ACAAGGCCAG AGGTACTCTG 
ATTGCACTTC TGATGGGCGT GGACAGTTCT GAGACTTGCA GGCACTTATC ATGCGTGCTG 
TCAGGACTGA TGGCTGATTT AGATGCTCTA GATGTGTGTG GGCGTACAGA GATCAGAAAT 
TATCGGAGGG AGGTGGTGGA AGATATCAAC AAATTACTAA AATATCTAGA TTTAGAAGAG 
GAAGCTGACA ATACACATGC ATTTGACCTG GGACAGAACC ATTCCATTAT AAAGATAGAA 
AATGTCCTCA AGAGGATGAG AGAAATGAAA AATGAACTTC TCCAGGCACA GAGCCCTCCT 
GAATTGTACC TGAGGTCCAA GACAGAGCTG CAGGGCTTGA TCGGGCAGCT GGACGAAGTG 
AGTCTGGAGA AAAACCCCTG CATCAGAGAG GCCAGGAGAA GAGCAGTGAT TGAGGTGCAG 
ACCCTCATCA CGTACCTGGA CCTGAAGGAG GCCCTCGAGA AGAGGAAGCT GTTCCCGTGT 
GAGGAGACCC CCCCACATAA GGCTGTGTGG AATGTCCTTG GAAACCTGTC AGAGATCCAG 
GGTGAAGTCC TCTCCTTTGG TGGGAACCGA ACTGATAAGA ACTACATTCG TCTGGAGGAG 
CTACTGACCA AACAGTTGCT GACTCTGGAT GCTGTTGACC CACTGGGAGA AGAGAAGTGT 
AAGGCTGCCA GGAAGCAGGC CGTGAAGCTG GCCCAGAACA TCCTCAGCTA CCTTGACATG 
AAGTCTGATG AGTGGGAGTA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Bag5 ( XM_006240603.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006240665.1 Rattus norvegicus BCL2-associated athanogene 5 (Bag5), transcript variant X3, mRNA.

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CloneID	ORa12465
Clone ID Related Accession (Same CDS sequence)	XM_006240601.2 , XM_006240602.2 , XM_006240603.3 , NM_001008526.2
Accession Version	XM_006240603.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1344bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	BAG family molecular chaperone regulator 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005105.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006240603.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATATGG GAAACCAACA CCCTTCTATT AGTAGGCTTC AGGAGATCCA ACGGGAAGTA 
AAGAGTATAG AGCAGCAAGT GGTTGGCTTC AGTGGCCTGT CGGATGACAA GAATTACAAG 
AGACTGGAGA GGATTCTGAC GAAACAACTT TTTGAAATCG ACTCTGTGGA TACAGAAGGG 
AAAGGAGACA TCCAGCAAGC TAGGAAGAGG GCAGCACAGG ACACAGAACG CCTTCTCAAA 
GAGTTGGAGC AGAACGCGAA CCACCCACAC CGGATTGAAA TCAAGAATAT CTTTCAAGAA 
GCTCAGGCCC TTGTGAAAGA AAAGACTGTG CCCTTTTACA GTGGAAGCAA CTGTGTGACT 
AGCGAGTTTG AGGAAGCCAT CCAGGACATC ATTCTGAGGC TGACACATGT TAAAACAGGA 
GGGAAGATCT CCTTGCGGAA AGCAAGGTAC CACACACTAA CCAAGATCTG TGCGGTACAA 
GAGATTATTG AAGACTGTGT GAGGAAACAG CCTTCCCTGC CACTTTCCGA GGATGTGCAT 
CCTTCTGTCG CCAAGATCAA TTCTGTGATG TGTGAGGTGA ACAAGGCCAG AGGTACTCTG 
ATTGCACTTC TGATGGGCGT GGACAGTTCT GAGACTTGCA GGCACTTATC ATGCGTGCTG 
TCAGGACTGA TGGCTGATTT AGATGCTCTA GATGTGTGTG GGCGTACAGA GATCAGAAAT 
TATCGGAGGG AGGTGGTGGA AGATATCAAC AAATTACTAA AATATCTAGA TTTAGAAGAG 
GAAGCTGACA ATACACATGC ATTTGACCTG GGACAGAACC ATTCCATTAT AAAGATAGAA 
AATGTCCTCA AGAGGATGAG AGAAATGAAA AATGAACTTC TCCAGGCACA GAGCCCTCCT 
GAATTGTACC TGAGGTCCAA GACAGAGCTG CAGGGCTTGA TCGGGCAGCT GGACGAAGTG 
AGTCTGGAGA AAAACCCCTG CATCAGAGAG GCCAGGAGAA GAGCAGTGAT TGAGGTGCAG 
ACCCTCATCA CGTACCTGGA CCTGAAGGAG GCCCTCGAGA AGAGGAAGCT GTTCCCGTGT 
GAGGAGACCC CCCCACATAA GGCTGTGTGG AATGTCCTTG GAAACCTGTC AGAGATCCAG 
GGTGAAGTCC TCTCCTTTGG TGGGAACCGA ACTGATAAGA ACTACATTCG TCTGGAGGAG 
CTACTGACCA AACAGTTGCT GACTCTGGAT GCTGTTGACC CACTGGGAGA AGAGAAGTGT 
AAGGCTGCCA GGAAGCAGGC CGTGAAGCTG GCCCAGAACA TCCTCAGCTA CCTTGACATG 
AAGTCTGATG AGTGGGAGTA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006240665.1
CDS	212..1555
Translation	MDMGNQHPSISRLQEIQREVKSIEQQVVGFSGLSDDKNYKRLERILTKQLFEIDSVDTEGKGDIQQARKRAAQDTERLLKELEQNANHPHRIEIKNIFQEAQALVKEKTVPFYSGSNCVTSEFEEAIQDIILRLTHVKTGGKISLRKARYHTLTKICAVQEIIEDCVRKQPSLPLSEDVHPSVAKINSVMCEVNKARGTLIALLMGVDSSETCRHLSCVLSGLMADLDALDVCGRTEIRNYRREVVEDINKLLKYLDLEEEADNTHAFDLGQNHSIIKIENVLKRMREMKNELLQAQSPPELYLRSKTELQGLIGQLDEVSLEKNPCIREARRRAVIEVQTLITYLDLKEALEKRKLFPCEETPPHKAVWNVLGNLSEIQGEVLSFGGNRTDKNYIRLEELLTKQLLTLDAVDPLGEEKCKAARKQAVKLAQNILSYLDMKSDEWEY

Target ORF information:

RefSeq Version	XM_006240603.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus BCL2-associated athanogene 5 (Bag5), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006240603.3

ORF Insert Sequence:

ATGGATATGG GAAACCAACA CCCTTCTATT AGTAGGCTTC AGGAGATCCA ACGGGAAGTA 
AAGAGTATAG AGCAGCAAGT GGTTGGCTTC AGTGGCCTGT CGGATGACAA GAATTACAAG 
AGACTGGAGA GGATTCTGAC GAAACAACTT TTTGAAATCG ACTCTGTGGA TACAGAAGGG 
AAAGGAGACA TCCAGCAAGC TAGGAAGAGG GCAGCACAGG ACACAGAACG CCTTCTCAAA 
GAGTTGGAGC AGAACGCGAA CCACCCACAC CGGATTGAAA TCAAGAATAT CTTTCAAGAA 
GCTCAGGCCC TTGTGAAAGA AAAGACTGTG CCCTTTTACA GTGGAAGCAA CTGTGTGACT 
AGCGAGTTTG AGGAAGCCAT CCAGGACATC ATTCTGAGGC TGACACATGT TAAAACAGGA 
GGGAAGATCT CCTTGCGGAA AGCAAGGTAC CACACACTAA CCAAGATCTG TGCGGTACAA 
GAGATTATTG AAGACTGTGT GAGGAAACAG CCTTCCCTGC CACTTTCCGA GGATGTGCAT 
CCTTCTGTCG CCAAGATCAA TTCTGTGATG TGTGAGGTGA ACAAGGCCAG AGGTACTCTG 
ATTGCACTTC TGATGGGCGT GGACAGTTCT GAGACTTGCA GGCACTTATC ATGCGTGCTG 
TCAGGACTGA TGGCTGATTT AGATGCTCTA GATGTGTGTG GGCGTACAGA GATCAGAAAT 
TATCGGAGGG AGGTGGTGGA AGATATCAAC AAATTACTAA AATATCTAGA TTTAGAAGAG 
GAAGCTGACA ATACACATGC ATTTGACCTG GGACAGAACC ATTCCATTAT AAAGATAGAA 
AATGTCCTCA AGAGGATGAG AGAAATGAAA AATGAACTTC TCCAGGCACA GAGCCCTCCT 
GAATTGTACC TGAGGTCCAA GACAGAGCTG CAGGGCTTGA TCGGGCAGCT GGACGAAGTG 
AGTCTGGAGA AAAACCCCTG CATCAGAGAG GCCAGGAGAA GAGCAGTGAT TGAGGTGCAG 
ACCCTCATCA CGTACCTGGA CCTGAAGGAG GCCCTCGAGA AGAGGAAGCT GTTCCCGTGT 
GAGGAGACCC CCCCACATAA GGCTGTGTGG AATGTCCTTG GAAACCTGTC AGAGATCCAG 
GGTGAAGTCC TCTCCTTTGG TGGGAACCGA ACTGATAAGA ACTACATTCG TCTGGAGGAG 
CTACTGACCA AACAGTTGCT GACTCTGGAT GCTGTTGACC CACTGGGAGA AGAGAAGTGT 
AAGGCTGCCA GGAAGCAGGC CGTGAAGCTG GCCCAGAACA TCCTCAGCTA CCTTGACATG 
AAGTCTGATG AGTGGGAGTA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

GRP78 Interacting Partner Bag5 Responds to ER Stress and Protects Cardiomyocytes From ER Stress-Induced Apoptosis.
Journal of cellular biochemistry117(8)1813-21(2016 08)
Gupta MK,Tahrir FG,Knezevic T,White MK,Gordon J,Cheung JY,Khalili K,Feldman AM

The BAG2 and BAG5 proteins inhibit the ubiquitination of pathogenic ataxin3-80Q.
The International journal of neuroscience125(5)390-4(2015 May)
Che XQ,Tang BS,Wang HF,Yan XX,Jiang H,Shen L,Xu Q,Wang GH,Zhang HN,Wang CY,Guo JF

Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease.
Proceedings of the National Academy of Sciences of the United States of America111(7)2626-31(2014 Feb)
Beilina A,Rudenko IN,Kaganovich A,Civiero L,Chau H,Kalia SK,Kalia LV,Lobbestael E,Chia R,Ndukwe K,Ding J,Nalls MA,,,Olszewski M,Hauser DN,Kumaran R,Lozano AM,Baekelandt V,Greene LE,Taymans JM,Greggio E,Cookson MR

BAG5 protects against mitochondrial oxidative damage through regulating PINK1 degradation.
PloS one9(1)e86276(2014)
Wang X,Guo J,Fei E,Mu Y,He S,Che X,Tan J,Xia K,Zhang Z,Wang G,Tang B

High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy.
Nature504(7479)291-5(2013 Dec)
Hasson SA,Kane LA,Yamano K,Huang CH,Sliter DA,Buehler E,Wang C,Heman-Ackah SM,Hessa T,Guha R,Martin SE,Youle RJ

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Bag5 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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