Wdr48 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Wdr48
Entrez Gene ID	363164
Full Name	WD repeat domain 48
Synonyms	RGD1309702
General protein information	Preferred Names WD repeat domain 48 Names WD repeat-containing protein 48
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 8 Map Location: 8q32

mRNA and Protein(s)

mRNA	Protein	Name
XM_017595770.1	XP_017451259.1	WD repeat-containing protein 48 isoform X1
NM_001135895.2	NP_001129367.1	WD repeat-containing protein 48

Pathways from BioSystems

Homologies

Homo sapiens (human)	WDR48	NP_065890.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001361	XP_321784.3
Bos taurus (cattle)	WDR48	NP_001069992.1
Mus musculus (house mouse)	Wdr48	NP_080512.1
Drosophila melanogaster (fruit fly)	CG9062	NP_001260886.1
	WDR48	XP_001083670.2
Gallus gallus (chicken)	WDR48	NP_001026135.1
Caenorhabditis elegans (roundworm)	F35G12.4	NP_497930.2
Xenopus tropicalis (tropical clawed frog)	wdr48	NP_001072858.1
Pan troglodytes (chimpanzee)	WDR48	XP_516374.3
Canis lupus familiaris (dog)	WDR48	XP_860103.1
Rattus norvegicus (Norway rat)	Wdr48	NP_001129367.1
Danio rerio (zebrafish)	wdr48	NP_999874.1
Arabidopsis thaliana (thale cress)	LRS1	NP_850516.1
Oryza sativa (rice)	Os12g0165000	NP_001066238.1

Gene Ontology
Bibliography

Related articles in PubMed

WD repeat protein WDR48 in complex with deubiquitinase USP12 suppresses Akt-dependent cell survival signaling by stabilizing PH domain leucine-rich repeat protein phosphatase 1 (PHLPP1).
Gangula NR, Maddika S
The Journal of biological chemistry288(48)34545-54(2013 Nov)

Inactivation of Uaf1 causes defective homologous recombination and early embryonic lethality in mice.
Park E, Kim JM, Primack B, Weinstock DM, Moreau LA, Parmar K, D'Andrea AD
Molecular and cellular biology33(22)4360-70(2013 Nov)

UAF1 is a subunit of multiple deubiquitinating enzyme complexes.
Cohn MA, Kee Y, Haas W, Gygi SP, D'Andrea AD
The Journal of biological chemistry284(8)5343-51(2009 Feb)

A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway.
Cohn MA, Kowal P, Yang K, Haas W, Huang TT, Gygi SP, D'Andrea AD
Molecular cell28(5)786-97(2007 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Wdr48 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Wdr48 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa03100	NM_001135895.2 Latest version!	Rattus norvegicus WD repeat domain 48 (Wdr48), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa62474	XM_017595770.1 Latest version!	Rattus norvegicus WD repeat domain 48 (Wdr48), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Wdr48 ( NM_001135895.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001129367.1 Rattus norvegicus WD repeat domain 48 (Wdr48), mRNA.

Price & Availability↑

CloneID	ORa03100
Clone ID Related Accession (Same CDS sequence)	NM_001135895.2
Accession Version	NM_001135895.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2031bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	WD repeat-containing protein 48
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07071739.1. On Jul 11, 2009 this sequence version replaced NM_001135895.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGCCC ATCACCGGCA GAACACAGCC GGGCGGAGAA AAGTGCAGGT TTCCTATGTA 
ATTCGAGATG AAGTGGAGAA GTACAATCGG AACGGAGTCA ATGCCCTGCA ACTGGACCCA 
GCACTCAACA GACTCTTCAC AGCAGGTCGA GACTCCATCA TAAGAATATG GAGTGTCAAT 
CAGCACAAGC AAGATCCATA CATAGCATCT ATGGAGCACC ACACAGACTG GGTGAACGAT 
GTTGTACTCT GTTGCAATGG GAAAACACTA ATATCTGCTT CTTCAGACAC AACAGTAAAA 
GTCTGGAATG CACATAAAGG GTTCTGCATG TCCACCCTCA GGACGCATAA GGACTATGTC 
AAGGCCTTGG CGTATGCCAA GGATAAAGAG CTGGTAGCAT CGGCTGGGCT GGACAGACAG 
ATATTCCTTT GGGATGTGAA CACTTTGACA GCACTGACTG CCTCAAACAA CACTGTCACA 
ACTTCTTCTT TAAGTGGGAA CAAAGATTCC ATTTATAGCC TGGCCATGAA CCAACTGGGA 
ACAATCATTG TATCTGGGTC CACTGAGAAG GTTCTAAGAG TGTGGGATCC AAGAACCTGT 
GCGAAACTCA TGAAGCTGAA AGGACACACG GACAATGTGA AGGCCCTGCT GCTGCACAGG 
GACGGCACAC AGTGCCTCTC TGGGAGTTCT GATGGGACGA TTCGCCTGTG GTCCCTTGGC 
CAGCAGAGAT GTATAGCAAC ATACCGAGTC CATGATGAGG GCGTTTGGGC CCTACAGGTC 
AATGATGCCT TCACACATGT CTATTCTGGG GGACGGGACA GGAAGATCTA CTGCACAGAC 
CTAAGGAACC CTGACATTCG GGTGCTGATT TGTGAAGAAA AAGCACCAGT TCTCAAGATG 
GAACTTGACA GATCAGCAGA TCCCCCTCCT GCAATCTGGG TTGCAACAAC AAAGTCCACA 
GTAAATAAGT GGACACTGAA GGGAATTCAT AATTTCCGAG CCTCTGGTGA TTATGACAAT 
GATTGTACAA ACCCCATAAC GCCCCTCTGC ACACAGCCGG ACCAAGTTAT TAAAGGGGGC 
GCTAGTATCA TCCAGTGCCA CATCCTAAAT GATAAGCGAC ATATATTGAC CAAAGATACG 
AATAACAATG TGGCCTACTG GGACGTGTTG AAGGCATGCA AAGTGGAAGA TTTGGGCAAA 
GTGGACTTCG AAGATGAAAT TAAGAAAAGA TTTAAAATGG TGTATGTTCC AAATTGGTTC 
TCAGTAGACC TAAAAACAGG GATGCTGACC ATTACTCTGG ATGAAAGCGA CTGCTTCGCT 
GCCTGGGTTT CTGCGAAAGA TGCTGGCTTC AGCAGTCCCG ATGGGTCAGA CCCAAAACTG 
AACTTAGGAG GACTTCTACT ACAGGCCCTC CTGGAGTACT GGCCCAGAAC ACATGTGACT 
CCCATGGACG AGGAGGAGAA TGAAGTGAAC CATGTGAGTG GGGAACAGGA GAGCCGAGTC 
CAGAAAGGAA ATGGCTATTT CCAGGTGCCC CCCCACACCC CCGTGATCTT TGGAGAAGCT 
GGAGGTCGCA CACTTTTCAG GCTGCTCTGC CGGGACTCCG GGGGCGAGAC CGAGGCAATG 
CTTCTCAATG AGACCGTGCC ACAATGGGTG ATCGACATCA CTGTGGATAA AAATATGCCC 
AAATTCAACA AAATTCCTTT CTACCTCCAA CCTCATGCAT CTTCAGGAGC AAAAACTTTA 
AAAAAAGACA GACTGTCTGC CAGTGACATG CTGCAGGTCC GGAAGGTGAT GGAACACGTC 
TACGAGAAGA TTATCAACCT GGATAACGAG TCCCAAACCA CCAGCTCTTC TAATAATGAA 
AAACCAGAGC AGGAGAAGGA GGAGGACATT GCTGTGTTGG CAGAGGAGAA AATTGAGCTT 
CTGTGCCAGG ACCAGGTTTT GGACCCCAAT ATGGACCTTC GGACAGTAAA GCACTTCATA 
TGGAAGAGTG GTGGGGACCT CACCCTCCAT TACCGTCAGA AGTCCACGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001129367.1
CDS	20..2050
Translation	MAAHHRQNTAGRRKVQVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDVVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKMELDRSADPPPAIWVATTKSTVNKWTLKGIHNFRASGDYDNDCTNPITPLCTQPDQVIKGGASIIQCHILNDKRHILTKDTNNNVAYWDVLKACKVEDLGKVDFEDEIKKRFKMVYVPNWFSVDLKTGMLTITLDESDCFAAWVSAKDAGFSSPDGSDPKLNLGGLLLQALLEYWPRTHVTPMDEEENEVNHVSGEQESRVQKGNGYFQVPPHTPVIFGEAGGRTLFRLLCRDSGGETEAMLLNETVPQWVIDITVDKNMPKFNKIPFYLQPHASSGAKTLKKDRLSASDMLQVRKVMEHVYEKIINLDNESQTTSSSNNEKPEQEKEEDIAVLAEEKIELLCQDQVLDPNMDLRTVKHFIWKSGGDLTLHYRQKST

Target ORF information:

RefSeq Version	NM_001135895.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus WD repeat domain 48 (Wdr48), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001135895.2

ORF Insert Sequence:

ATGGCGGCCC ATCACCGGCA GAACACAGCC GGGCGGAGAA AAGTGCAGGT TTCCTATGTA 
ATTCGAGATG AAGTGGAGAA GTACAATCGG AACGGAGTCA ATGCCCTGCA ACTGGACCCA 
GCACTCAACA GACTCTTCAC AGCAGGTCGA GACTCCATCA TAAGAATATG GAGTGTCAAT 
CAGCACAAGC AAGATCCATA CATAGCATCT ATGGAGCACC ACACAGACTG GGTGAACGAT 
GTTGTACTCT GTTGCAATGG GAAAACACTA ATATCTGCTT CTTCAGACAC AACAGTAAAA 
GTCTGGAATG CACATAAAGG GTTCTGCATG TCCACCCTCA GGACGCATAA GGACTATGTC 
AAGGCCTTGG CGTATGCCAA GGATAAAGAG CTGGTAGCAT CGGCTGGGCT GGACAGACAG 
ATATTCCTTT GGGATGTGAA CACTTTGACA GCACTGACTG CCTCAAACAA CACTGTCACA 
ACTTCTTCTT TAAGTGGGAA CAAAGATTCC ATTTATAGCC TGGCCATGAA CCAACTGGGA 
ACAATCATTG TATCTGGGTC CACTGAGAAG GTTCTAAGAG TGTGGGATCC AAGAACCTGT 
GCGAAACTCA TGAAGCTGAA AGGACACACG GACAATGTGA AGGCCCTGCT GCTGCACAGG 
GACGGCACAC AGTGCCTCTC TGGGAGTTCT GATGGGACGA TTCGCCTGTG GTCCCTTGGC 
CAGCAGAGAT GTATAGCAAC ATACCGAGTC CATGATGAGG GCGTTTGGGC CCTACAGGTC 
AATGATGCCT TCACACATGT CTATTCTGGG GGACGGGACA GGAAGATCTA CTGCACAGAC 
CTAAGGAACC CTGACATTCG GGTGCTGATT TGTGAAGAAA AAGCACCAGT TCTCAAGATG 
GAACTTGACA GATCAGCAGA TCCCCCTCCT GCAATCTGGG TTGCAACAAC AAAGTCCACA 
GTAAATAAGT GGACACTGAA GGGAATTCAT AATTTCCGAG CCTCTGGTGA TTATGACAAT 
GATTGTACAA ACCCCATAAC GCCCCTCTGC ACACAGCCGG ACCAAGTTAT TAAAGGGGGC 
GCTAGTATCA TCCAGTGCCA CATCCTAAAT GATAAGCGAC ATATATTGAC CAAAGATACG 
AATAACAATG TGGCCTACTG GGACGTGTTG AAGGCATGCA AAGTGGAAGA TTTGGGCAAA 
GTGGACTTCG AAGATGAAAT TAAGAAAAGA TTTAAAATGG TGTATGTTCC AAATTGGTTC 
TCAGTAGACC TAAAAACAGG GATGCTGACC ATTACTCTGG ATGAAAGCGA CTGCTTCGCT 
GCCTGGGTTT CTGCGAAAGA TGCTGGCTTC AGCAGTCCCG ATGGGTCAGA CCCAAAACTG 
AACTTAGGAG GACTTCTACT ACAGGCCCTC CTGGAGTACT GGCCCAGAAC ACATGTGACT 
CCCATGGACG AGGAGGAGAA TGAAGTGAAC CATGTGAGTG GGGAACAGGA GAGCCGAGTC 
CAGAAAGGAA ATGGCTATTT CCAGGTGCCC CCCCACACCC CCGTGATCTT TGGAGAAGCT 
GGAGGTCGCA CACTTTTCAG GCTGCTCTGC CGGGACTCCG GGGGCGAGAC CGAGGCAATG 
CTTCTCAATG AGACCGTGCC ACAATGGGTG ATCGACATCA CTGTGGATAA AAATATGCCC 
AAATTCAACA AAATTCCTTT CTACCTCCAA CCTCATGCAT CTTCAGGAGC AAAAACTTTA 
AAAAAAGACA GACTGTCTGC CAGTGACATG CTGCAGGTCC GGAAGGTGAT GGAACACGTC 
TACGAGAAGA TTATCAACCT GGATAACGAG TCCCAAACCA CCAGCTCTTC TAATAATGAA 
AAACCAGAGC AGGAGAAGGA GGAGGACATT GCTGTGTTGG CAGAGGAGAA AATTGAGCTT 
CTGTGCCAGG ACCAGGTTTT GGACCCCAAT ATGGACCTTC GGACAGTAAA GCACTTCATA 
TGGAAGAGTG GTGGGGACCT CACCCTCCAT TACCGTCAGA AGTCCACGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Wdr48 ( XM_017595770.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017451259.1 Rattus norvegicus WD repeat domain 48 (Wdr48), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa62474
Clone ID Related Accession (Same CDS sequence)	XM_017595770.1
Accession Version	XM_017595770.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2076bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	WD repeat-containing protein 48 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005107.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCCTAC TGCCCGCTCA CCTGCCTCTG CTCTCGGCCG CCTTCCTCCG GAACAGCCGC 
GACCCGGCGG CGGAGGCCGC GCGGCGCCCG CGGGTTTCCT ATGTAATTCG AGATGAAGTG 
GAGAAGTACA ATCGGAACGG AGTCAATGCC CTGCAACTGG ACCCAGCACT CAACAGACTC 
TTCACAGCAG GTCGAGACTC CATCATAAGA ATATGGAGTG TCAATCAGCA CAAGCAAGAT 
CCATACATAG CATCTATGGA GCACCACACA GACTGGGTGA ACGATGTTGT ACTCTGTTGC 
AATGGGAAAA CACTAATATC TGCTTCTTCA GACACAACAG TAAAAGTCTG GAATGCACAT 
AAAGGGTTCT GCATGTCCAC CCTCAGGACG CATAAGGACT ATGTCAAGGC CTTGGCGTAT 
GCCAAGGATA AAGAGCTGGT AGCATCGGCT GGGCTGGACA GACAGATATT CCTTTGGGAT 
GTGAACACTT TGACAGCACT GACTGCCTCA AACAACACTG TCACAACTTC TTCTTTAAGT 
GGGAACAAAG ATTCCATTTA TAGCCTGGCC ATGAACCAAC TGGGAACAAT CATTGTATCT 
GGGTCCACTG AGAAGGTTCT AAGAGTGTGG GATCCAAGAA CCTGTGCGAA ACTCATGAAG 
CTGAAAGGAC ACACGGACAA TGTGAAGGCC CTGCTGCTGC ACAGGGACGG CACACAGTGC 
CTCTCTGGGA GTTCTGATGG GACGATTCGC CTGTGGTCCC TTGGCCAGCA GAGATGTATA 
GCAACATACC GAGTCCATGA TGAGGGCGTT TGGGCCCTAC AGGTCAATGA TGCCTTCACA 
CATGTCTATT CTGGGGGACG GGACAGGAAG ATCTACTGCA CAGACCTAAG GAACCCTGAC 
ATTCGGGTGC TGATTTGTGA AGAAAAAGCA CCAGTTCTCA AGATGGAACT TGACAGATCA 
GCAGATCCCC CTCCTGCAAT CTGGGTTGCA ACAACAAAGT CCACAGTAAA TAAGTGGACA 
CTGAAGGGAA TTCATAATTT CCGAGCCTCT GGTGATTATG ACAATGATTG TACAAACCCC 
ATAACGCCCC TCTGCACACA GCCGGACCAA GTTATTAAAG GGGGCGCTAG TATCATCCAG 
TGCCACATCC TAAATGATAA GCGACATATA TTGACCAAAG ATACGAATAA CAATGTGGCC 
TACTGGGACG TGTTGAAGGC ATGCAAAGTG GAAGATTTGG GCAAAGTGGA CTTCGAAGAT 
GAAATTAAGA AAAGATTTAA AATGGTGTAT GTTCCAAATT GGTTCTCAGT AGACCTAAAA 
ACAGGGATGC TGACCATTAC TCTGGATGAA AGCGACTGCT TCGCTGCCTG GGTTTCTGCG 
AAAGATGCTG GCTTCAGCAG TCCCGATGGG TCAGACCCAA AACTGAACTT AGGAGGACTT 
CTACTACAGG CCCTCCTGGA GTACTGGCCC AGAACACATG TGACTCCCAT GGACGAGGAG 
GAGAATGAAG TGAACCATGT GAGTGGGGAA CAGGAGAGCC GAGTCCAGAA AGGAAATGGC 
TATTTCCAGG TGCCCCCCCA CACCCCCGTG ATCTTTGGAG AAGCTGGAGG TCGCACACTT 
TTCAGGCTGC TCTGCCGGGA CTCCGGGGGC GAGACCGAGG CAATGCTTCT CAATGAGACC 
GTGCCACAAT GGGTGATCGA CATCACTGTG GATAAAAATA TGCCCAAATT CAACAAAATT 
CCTTTCTACC TCCAACCTCA TGCATCTTCA GGAGCAAAAA CTTTAAAAAA AGACAGACTG 
TCTGCCAGTG ACATGCTGCA GGTCCGGAAG GTGATGGAAC ACGTCTACGA GAAGATTATC 
AACCTGGATA ACGAGTCCCA AACCACCAGC TCTTCTAATA ATGAAAAACC AGAGCAGGAG 
AAGGAGGAGG ACATTGCTGT GTTGGCAGAG GAGAAAATTG AGCTTCTGTG CCAGGACCAG 
GTTTTGGACC CCAATATGGA CCTTCGGACA GTAAAGCACT TCATATGGAA GAGTGGTGGG 
GACCTCACCC TCCATTACCG TCAGAAGTCC ACGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017451259.1
CDS	93..2168
Translation	MGLLPAHLPLLSAAFLRNSRDPAAEAARRPRVSYVIRDEVEKYNRNGVNALQLDPALNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDVVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLHRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEKAPVLKMELDRSADPPPAIWVATTKSTVNKWTLKGIHNFRASGDYDNDCTNPITPLCTQPDQVIKGGASIIQCHILNDKRHILTKDTNNNVAYWDVLKACKVEDLGKVDFEDEIKKRFKMVYVPNWFSVDLKTGMLTITLDESDCFAAWVSAKDAGFSSPDGSDPKLNLGGLLLQALLEYWPRTHVTPMDEEENEVNHVSGEQESRVQKGNGYFQVPPHTPVIFGEAGGRTLFRLLCRDSGGETEAMLLNETVPQWVIDITVDKNMPKFNKIPFYLQPHASSGAKTLKKDRLSASDMLQVRKVMEHVYEKIINLDNESQTTSSSNNEKPEQEKEEDIAVLAEEKIELLCQDQVLDPNMDLRTVKHFIWKSGGDLTLHYRQKST

Target ORF information:

RefSeq Version	XM_017595770.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus WD repeat domain 48 (Wdr48), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017595770.1

ORF Insert Sequence:

ATGGGCCTAC TGCCCGCTCA CCTGCCTCTG CTCTCGGCCG CCTTCCTCCG GAACAGCCGC 
GACCCGGCGG CGGAGGCCGC GCGGCGCCCG CGGGTTTCCT ATGTAATTCG AGATGAAGTG 
GAGAAGTACA ATCGGAACGG AGTCAATGCC CTGCAACTGG ACCCAGCACT CAACAGACTC 
TTCACAGCAG GTCGAGACTC CATCATAAGA ATATGGAGTG TCAATCAGCA CAAGCAAGAT 
CCATACATAG CATCTATGGA GCACCACACA GACTGGGTGA ACGATGTTGT ACTCTGTTGC 
AATGGGAAAA CACTAATATC TGCTTCTTCA GACACAACAG TAAAAGTCTG GAATGCACAT 
AAAGGGTTCT GCATGTCCAC CCTCAGGACG CATAAGGACT ATGTCAAGGC CTTGGCGTAT 
GCCAAGGATA AAGAGCTGGT AGCATCGGCT GGGCTGGACA GACAGATATT CCTTTGGGAT 
GTGAACACTT TGACAGCACT GACTGCCTCA AACAACACTG TCACAACTTC TTCTTTAAGT 
GGGAACAAAG ATTCCATTTA TAGCCTGGCC ATGAACCAAC TGGGAACAAT CATTGTATCT 
GGGTCCACTG AGAAGGTTCT AAGAGTGTGG GATCCAAGAA CCTGTGCGAA ACTCATGAAG 
CTGAAAGGAC ACACGGACAA TGTGAAGGCC CTGCTGCTGC ACAGGGACGG CACACAGTGC 
CTCTCTGGGA GTTCTGATGG GACGATTCGC CTGTGGTCCC TTGGCCAGCA GAGATGTATA 
GCAACATACC GAGTCCATGA TGAGGGCGTT TGGGCCCTAC AGGTCAATGA TGCCTTCACA 
CATGTCTATT CTGGGGGACG GGACAGGAAG ATCTACTGCA CAGACCTAAG GAACCCTGAC 
ATTCGGGTGC TGATTTGTGA AGAAAAAGCA CCAGTTCTCA AGATGGAACT TGACAGATCA 
GCAGATCCCC CTCCTGCAAT CTGGGTTGCA ACAACAAAGT CCACAGTAAA TAAGTGGACA 
CTGAAGGGAA TTCATAATTT CCGAGCCTCT GGTGATTATG ACAATGATTG TACAAACCCC 
ATAACGCCCC TCTGCACACA GCCGGACCAA GTTATTAAAG GGGGCGCTAG TATCATCCAG 
TGCCACATCC TAAATGATAA GCGACATATA TTGACCAAAG ATACGAATAA CAATGTGGCC 
TACTGGGACG TGTTGAAGGC ATGCAAAGTG GAAGATTTGG GCAAAGTGGA CTTCGAAGAT 
GAAATTAAGA AAAGATTTAA AATGGTGTAT GTTCCAAATT GGTTCTCAGT AGACCTAAAA 
ACAGGGATGC TGACCATTAC TCTGGATGAA AGCGACTGCT TCGCTGCCTG GGTTTCTGCG 
AAAGATGCTG GCTTCAGCAG TCCCGATGGG TCAGACCCAA AACTGAACTT AGGAGGACTT 
CTACTACAGG CCCTCCTGGA GTACTGGCCC AGAACACATG TGACTCCCAT GGACGAGGAG 
GAGAATGAAG TGAACCATGT GAGTGGGGAA CAGGAGAGCC GAGTCCAGAA AGGAAATGGC 
TATTTCCAGG TGCCCCCCCA CACCCCCGTG ATCTTTGGAG AAGCTGGAGG TCGCACACTT 
TTCAGGCTGC TCTGCCGGGA CTCCGGGGGC GAGACCGAGG CAATGCTTCT CAATGAGACC 
GTGCCACAAT GGGTGATCGA CATCACTGTG GATAAAAATA TGCCCAAATT CAACAAAATT 
CCTTTCTACC TCCAACCTCA TGCATCTTCA GGAGCAAAAA CTTTAAAAAA AGACAGACTG 
TCTGCCAGTG ACATGCTGCA GGTCCGGAAG GTGATGGAAC ACGTCTACGA GAAGATTATC 
AACCTGGATA ACGAGTCCCA AACCACCAGC TCTTCTAATA ATGAAAAACC AGAGCAGGAG 
AAGGAGGAGG ACATTGCTGT GTTGGCAGAG GAGAAAATTG AGCTTCTGTG CCAGGACCAG 
GTTTTGGACC CCAATATGGA CCTTCGGACA GTAAAGCACT TCATATGGAA GAGTGGTGGG 
GACCTCACCC TCCATTACCG TCAGAAGTCC ACGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

WD repeat protein WDR48 in complex with deubiquitinase USP12 suppresses Akt-dependent cell survival signaling by stabilizing PH domain leucine-rich repeat protein phosphatase 1 (PHLPP1).
The Journal of biological chemistry288(48)34545-54(2013 Nov)
Gangula NR,Maddika S

Inactivation of Uaf1 causes defective homologous recombination and early embryonic lethality in mice.
Molecular and cellular biology33(22)4360-70(2013 Nov)
Park E,Kim JM,Primack B,Weinstock DM,Moreau LA,Parmar K,D'Andrea AD

UAF1 is a subunit of multiple deubiquitinating enzyme complexes.
The Journal of biological chemistry284(8)5343-51(2009 Feb)
Cohn MA,Kee Y,Haas W,Gygi SP,D'Andrea AD

A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway.
Molecular cell28(5)786-97(2007 Dec)
Cohn MA,Kowal P,Yang K,Haas W,Huang TT,Gygi SP,D'Andrea AD

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Wdr48 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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