Os9 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Os9
Entrez Gene ID	362891
Full Name	OS9, endoplasmic reticulum lectin
Synonyms	Os-9
General protein information	Preferred Names OS9, endoplasmic reticulum lectin Names protein OS-9 amplified in osteosarcoma osteosarcoma amplified 9, endoplasmic reticulum lectin
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q22

mRNA and Protein(s)

mRNA	Protein	Name
NM_001007265.1	NP_001007266.1	protein OS-9 precursor
XM_006241461.1	XP_006241523.1	protein OS-9 isoform X1

Pathways from BioSystems

Homologies

	OS9	XP_001116363.1
Canis lupus familiaris (dog)	OS9	XP_005625606.1
Rattus norvegicus (Norway rat)	Os9	NP_001007266.1
Danio rerio (zebrafish)	os9	NP_001068576.1
Xenopus tropicalis (tropical clawed frog)	os9	XP_002933732.2
Mus musculus (house mouse)	Os9	NP_001164497.1
Bos taurus (cattle)	OS9	NP_001029397.1
Homo sapiens (human)	OS9	NP_006803.1
Pan troglodytes (chimpanzee)	OS9	XP_509170.2

Gene Ontology
Bibliography

Related articles in PubMed

Identification of ERAD components essential for dislocation of the null Hong Kong variant of ?-1-antitrypsin (NHK).
Zhong Y, Shen H, Wang Y, Yang Y, Yang P, Fang S
Biochemical and biophysical research communications458(2)424-8(2015 Mar)

SEL1L protein critically determines the stability of the HRD1-SEL1L endoplasmic reticulum-associated degradation (ERAD) complex to optimize the degradation kinetics of ERAD substrates.
Iida Y, Fujimori T, Okawa K, Nagata K, Wada I, Hosokawa N
The Journal of biological chemistry286(19)16929-39(2011 May)

Human OS-9, a lectin required for glycoprotein endoplasmic reticulum-associated degradation, recognizes mannose-trimmed N-glycans.
Hosokawa N, Kamiya Y, Kamiya D, Kato K, Nagata K
The Journal of biological chemistry284(25)17061-8(2009 Jun)

Regulation of oxygen homeostasis by hypoxia-inducible factor 1.
Semenza GL
Physiology (Bethesda, Md.)2497-106(2009 Apr)

[The cooperation of OS-9 and PHDs in hypoxia-induced pulmonary hypertension of rats].
Pan K, Dai AG, Hu RC
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology25(1)1-6(2009 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

HIF-1alpha, procollagen-proline dioxygenases and OS-9 are all involved in the pathogenesis of hypoxic pulmonary hypertension in rats.
Title: [The cooperation of OS-9 and PHDs in hypoxia-induced pulmonary hypertension of rats].

characterized alternatively spliced form and found that only the non-spliced form binds to meprin beta, suggesting the possible mechanism of the regulation of OS-9 function.
Title: A selective interaction between OS-9 and the carboxyl-terminal tail of meprin beta.

The following Os9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Os9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa11066	NM_001007265.1 Latest version!	Rattus norvegicus OS9, endoplasmic reticulum lectin (Os9), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00
ORa30252	XM_006241461.1 Latest version!	Rattus norvegicus OS9, endoplasmic reticulum lectin (Os9), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Os9 ( NM_001007265.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001007266.1 Rattus norvegicus OS9, endoplasmic reticulum lectin (Os9), mRNA.

Price & Availability↑

CloneID	ORa11066
Clone ID Related Accession (Same CDS sequence)	NM_001007265.1
Accession Version	NM_001007265.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2001bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Rattus norvegicus(Norway rat)
Product	protein OS-9 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC085907.1. On Nov 26, 2004 this sequence version replaced XM_343218.1. ##Evidence-Data-START## Transcript exon combination :: BC085907.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCGGCGG AGGCGCTGCT GTCCAGTCTG TTGGGATTGC TATTTCTGGG GCTCCTGTTA 
CCTGCGCATC TGACGGGCGG TGTCGGGAGC CTGAATTTGG AGGAGCTGAG TGAGATGCGT 
TATGGCATCC AGATCCTGCC GTTGCCTGTC ATGGGAGGGC AGAGCCAAGC TTCAGACGTG 
GTGGTTGTGT CTTCAAAGTA CAAACAGCGC TATGAGTGCC GCCTACCAGC TGGAGCTATT 
CACTTCCAGC GTGAAAGGGA GGAGGAGACA CCTGCTTACC AGGGGCCCGG GATTCCTGAA 
TTGTTGAGCC CAATGAGAGA TGCCCCTTGT CTGCTGAAGA CCAAGGACTG GTGGACATAT 
GAATTCTGTT ATGGACGCCA TATCCAGCAG TACCATATGG AAGACTCGGA GATCAAAGGT 
GACGTCCTCT ACCTTGGCTA CTACCAGTCA GCCTTCAACT GGGACGATGA AACAGCCAAG 
GCCTCCAAGC AGCATCGGCT GAAACGCTAC CACAGCCAGA CCTACGGCAA TGGGTCCAAA 
TGCGATCTCA ATGGGAAGCC CAGAGAAGCT GAAGTTCGGT TCCTGTGTGA CGAGGGCGCG 
GGCATATCTG GGGACTACAT CGATCGAGTA GATGAACCCT TCTCCTGCTC CTACGTACTG 
AGCATTCGGA CATCGAGGCT CTGCCCACAC CCTCTCCTCC GCCCACCAGC CAGCGCTGCC 
CCACAGGCTA TTCTATGTCA CCCAGCCCTG CAGCCTGACG AGTACATGGC CTACCTCCAG 
AGGCAAGCTG AGTCAAAGCA GCATGAAGAG AAAGTCACAG AGGAAGTTCA GGACACAGAC 
CACCAAGTGT GGAGTGGGAG CAAGGCTGCC GGAGCACCCC CAAAGAAAGA AGATGTGAGC 
CCCACCAAGG AAGATAAGGA ATCAGAGTTT TGGAAAATGC TTCAGGAGCC AGAGGAGCAG 
GCTACAGGAA CAGAGGAAGC ACAGGCAGGG GAACAGGACC TGAACCATGA GGCTGCAGCA 
GACCCAGCTC CAGCCCCTCC CACTGATTTT CAGAATAATG TGCAGGTCAA ACTCATCCGG 
AGTCCTGCAG ATTTGATTCG ATTGATCGAG GAGCTAAAAG GTGCAGAAAA GGGGAAGCCA 
AGCGTAAGGC AGGAGCAGCC TGGAGATGAT ACCACAGAGG CCCCGCAGAG GGAAGCGGAG 
GCGAAGGGAA AGGGTGGTGA ACCCCGGGGT CTCGTGGAAG AAGAGGATGG TGACGAGGAG 
GAGGAGGACG AGGACGAGGA TGAGCAGCAG CTCCTGGGAG AGTTCGAGAA GGAGTTGGAG 
GGGATGCTGC TGCCCTCGGA CCGAGAGCGC CTGCGCTCAG AGGTTAAGGC TGGCATGGAG 
CGCGAGCTGG AAAACATCAT CCAGGAGACA GAGAAGGAAC TGGACCCAGA AGGGCTGAGG 
AAGGAGTCTG AGCGGGAGCA GGCAATATTG GCTCTGACAT CCACTCTGGA CAAACTCATC 
AAGAGGCTGC AGGAGAGCCA GAGTCCAGAG CTTGTCCAGA AATACAAGAA AAGGAGAGTT 
GTCCCTCAAA AGCCTCCCCC ATCACCGCAC CCTACAGAGG AGGAGCCTGA GCACAGAGTC 
CGGGTCCGAG TCACCAAGCT CCGTCATGGA GGCCCCAATC AGGACCTGAC TGTCCTGGAG 
ATGAACCGGG AAAACCCACA GCTGAAACAG ATCGAGGGGC TGGTGACAGA AGTGCTGGAG 
AGGGAGGGGC TCACGGCGGA AGGCAAGATT GAGATCAAAA TTGTGCGACC CGGGGCTGAA 
GGTAAGGAGG AGGACACACG CTGGCTGACT GATGAGGACA CAAGAAACCT TAAGGAGATT 
TTCTTCAATA TCTTGGTGCA GGGAGCAGAA GAGGCCAATA AAGAACGCCA GCGACAGAGT 
GAGCTGGAGA GCAATTACCG CCGTGTATGG GGCTCTCCGG GTGGAGAGGA TACAGGGGAC 
CTGGATGAGT TTGACTTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001007266.1
CDS	30..2030
Translation	MAAEALLSSLLGLLFLGLLLPAHLTGGVGSLNLEELSEMRYGIQILPLPVMGGQSQASDVVVVSSKYKQRYECRLPAGAIHFQREREEETPAYQGPGIPELLSPMRDAPCLLKTKDWWTYEFCYGRHIQQYHMEDSEIKGDVLYLGYYQSAFNWDDETAKASKQHRLKRYHSQTYGNGSKCDLNGKPREAEVRFLCDEGAGISGDYIDRVDEPFSCSYVLSIRTSRLCPHPLLRPPASAAPQAILCHPALQPDEYMAYLQRQAESKQHEEKVTEEVQDTDHQVWSGSKAAGAPPKKEDVSPTKEDKESEFWKMLQEPEEQATGTEEAQAGEQDLNHEAAADPAPAPPTDFQNNVQVKLIRSPADLIRLIEELKGAEKGKPSVRQEQPGDDTTEAPQREAEAKGKGGEPRGLVEEEDGDEEEEDEDEDEQQLLGEFEKELEGMLLPSDRERLRSEVKAGMERELENIIQETEKELDPEGLRKESEREQAILALTSTLDKLIKRLQESQSPELVQKYKKRRVVPQKPPPSPHPTEEEPEHRVRVRVTKLRHGGPNQDLTVLEMNRENPQLKQIEGLVTEVLEREGLTAEGKIEIKIVRPGAEGKEEDTRWLTDEDTRNLKEIFFNILVQGAEEANKERQRQSELESNYRRVWGSPGGEDTGDLDEFDF

Target ORF information:

RefSeq Version	NM_001007265.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus OS9, endoplasmic reticulum lectin (Os9), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001007265.1

ORF Insert Sequence:

ATGGCGGCGG AGGCGCTGCT GTCCAGTCTG TTGGGATTGC TATTTCTGGG GCTCCTGTTA 
CCTGCGCATC TGACGGGCGG TGTCGGGAGC CTGAATTTGG AGGAGCTGAG TGAGATGCGT 
TATGGCATCC AGATCCTGCC GTTGCCTGTC ATGGGAGGGC AGAGCCAAGC TTCAGACGTG 
GTGGTTGTGT CTTCAAAGTA CAAACAGCGC TATGAGTGCC GCCTACCAGC TGGAGCTATT 
CACTTCCAGC GTGAAAGGGA GGAGGAGACA CCTGCTTACC AGGGGCCCGG GATTCCTGAA 
TTGTTGAGCC CAATGAGAGA TGCCCCTTGT CTGCTGAAGA CCAAGGACTG GTGGACATAT 
GAATTCTGTT ATGGACGCCA TATCCAGCAG TACCATATGG AAGACTCGGA GATCAAAGGT 
GACGTCCTCT ACCTTGGCTA CTACCAGTCA GCCTTCAACT GGGACGATGA AACAGCCAAG 
GCCTCCAAGC AGCATCGGCT GAAACGCTAC CACAGCCAGA CCTACGGCAA TGGGTCCAAA 
TGCGATCTCA ATGGGAAGCC CAGAGAAGCT GAAGTTCGGT TCCTGTGTGA CGAGGGCGCG 
GGCATATCTG GGGACTACAT CGATCGAGTA GATGAACCCT TCTCCTGCTC CTACGTACTG 
AGCATTCGGA CATCGAGGCT CTGCCCACAC CCTCTCCTCC GCCCACCAGC CAGCGCTGCC 
CCACAGGCTA TTCTATGTCA CCCAGCCCTG CAGCCTGACG AGTACATGGC CTACCTCCAG 
AGGCAAGCTG AGTCAAAGCA GCATGAAGAG AAAGTCACAG AGGAAGTTCA GGACACAGAC 
CACCAAGTGT GGAGTGGGAG CAAGGCTGCC GGAGCACCCC CAAAGAAAGA AGATGTGAGC 
CCCACCAAGG AAGATAAGGA ATCAGAGTTT TGGAAAATGC TTCAGGAGCC AGAGGAGCAG 
GCTACAGGAA CAGAGGAAGC ACAGGCAGGG GAACAGGACC TGAACCATGA GGCTGCAGCA 
GACCCAGCTC CAGCCCCTCC CACTGATTTT CAGAATAATG TGCAGGTCAA ACTCATCCGG 
AGTCCTGCAG ATTTGATTCG ATTGATCGAG GAGCTAAAAG GTGCAGAAAA GGGGAAGCCA 
AGCGTAAGGC AGGAGCAGCC TGGAGATGAT ACCACAGAGG CCCCGCAGAG GGAAGCGGAG 
GCGAAGGGAA AGGGTGGTGA ACCCCGGGGT CTCGTGGAAG AAGAGGATGG TGACGAGGAG 
GAGGAGGACG AGGACGAGGA TGAGCAGCAG CTCCTGGGAG AGTTCGAGAA GGAGTTGGAG 
GGGATGCTGC TGCCCTCGGA CCGAGAGCGC CTGCGCTCAG AGGTTAAGGC TGGCATGGAG 
CGCGAGCTGG AAAACATCAT CCAGGAGACA GAGAAGGAAC TGGACCCAGA AGGGCTGAGG 
AAGGAGTCTG AGCGGGAGCA GGCAATATTG GCTCTGACAT CCACTCTGGA CAAACTCATC 
AAGAGGCTGC AGGAGAGCCA GAGTCCAGAG CTTGTCCAGA AATACAAGAA AAGGAGAGTT 
GTCCCTCAAA AGCCTCCCCC ATCACCGCAC CCTACAGAGG AGGAGCCTGA GCACAGAGTC 
CGGGTCCGAG TCACCAAGCT CCGTCATGGA GGCCCCAATC AGGACCTGAC TGTCCTGGAG 
ATGAACCGGG AAAACCCACA GCTGAAACAG ATCGAGGGGC TGGTGACAGA AGTGCTGGAG 
AGGGAGGGGC TCACGGCGGA AGGCAAGATT GAGATCAAAA TTGTGCGACC CGGGGCTGAA 
GGTAAGGAGG AGGACACACG CTGGCTGACT GATGAGGACA CAAGAAACCT TAAGGAGATT 
TTCTTCAATA TCTTGGTGCA GGGAGCAGAA GAGGCCAATA AAGAACGCCA GCGACAGAGT 
GAGCTGGAGA GCAATTACCG CCGTGTATGG GGCTCTCCGG GTGGAGAGGA TACAGGGGAC 
CTGGATGAGT TTGACTTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Os9 ( XM_006241461.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006241523.1 Rattus norvegicus OS9, endoplasmic reticulum lectin (Os9), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa30252
Clone ID Related Accession (Same CDS sequence)	XM_006241461.1
Accession Version	XM_006241461.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1836bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	protein OS-9 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGCGG AGGCGCTGCT GTCCAGTCTG TTGGGATTGC TATTTCTGGG GCTCCTGTTA 
CCTGCGCATC TGACGGGCGG TGTCGGGAGC CTGAATTTGG AGGAGCTGAG TGAGATGCGT 
TATGGCATCC AGATCCTGCC GTTGCCTGTC ATGGGAGGGC AGAGCCAAGC TTCAGACGTG 
GTGGTTGTGT CTTCAAAGTA CAAACAGCGC TATGAGTGCC GCCTACCAGC TGGAGCTATT 
CACTTCCAGC GTGAAAGGGA GGAGGAGACA CCTGCTTACC AGGGGCCCGG GATTCCTGAA 
TTGTTGAGCC CAATGAGAGA TGCCCCTTGT CTGCTGAAGA CCAAGGACTG GTGGACATAT 
GAATTCTGTT ATGGACGCCA TATCCAGCAG TACCATATGG AAGACTCGGA GATCAAAGGT 
GACGTCCTCT ACCTTGGCTA CTACCAGTCA GCCTTCAACT GGGACGATGA AACAGCCAAG 
GCCTCCAAGC AGCATCGGCT GAAACGCTAC CACAGCCAGA CCTACGGCAA TGGGTCCAAA 
TGCGATCTCA ATGGGAAGCC CAGAGAAGCT GAAGTTCGGT TCCTGTGTGA CGAGGGCGCG 
GGCATATCTG GGGACTACAT CGATCGAGTA GATGAACCCT TCTCCTGCTC CTACGTACTG 
AGCATTCGGA CATCGAGGCT CTGCCCACAC CCTCTCCTCC GCCCACCAGC CAGCGCTGCC 
CCACAGGCTA TTCTATGTCA CCCAGCCCTG CAGCCTGACG AGTACATGGC CTACCTCCAG 
AGGCAAGCTG AGTCAAAGCA GCATGAAGAG AAAGTCACAG AGGAAGTTCA GGACACAGAC 
CACCAAGTGT GGAGTGGGAG CAAGGCTGCC GGAGCACCCC CAAAGAAAGA AGATGTGAGC 
CCCACCAAGG AAGATAAGGA ATCAGAGTTT TGGAAAATGC TTCAGGAGCC AGAGGAGCAG 
GCTACAGGAA CAGAGGAAGC ACAGGCAGGG GAACAGGACC TGAACCATGA GGCTGCAGCA 
GACCCAGCTC CAGCCCCTCC CACTGATTTT CAGAATAATG TGCAGGTCAA ACTCATCCGG 
AGTCCTGCAG ATTTGATTCG ATTGATCGAG GAGCTAAAAG GTGCAGAAAA GGGGAAGCCA 
AGCGTAAGGC AGGAGCAGCC TGGAGATGAT ACCACAGAGG CCCCGCAGAG GGAAGCGGAG 
GCGAAGGGAA AGGGTGGTGA ACCCCGGGGT CTCGTGGAAG AAGAGGATGG TGACGAGGAG 
GAGGAGGACG AGGACGAGGA TGAGCAGCAG CTCCTGGGAG AGTTCGAGAA GGAGTTGGAG 
GGGATGCTGC TGCCCTCGGA CCGAGAGCGC CTGCGCTCAG AGGTTAAGGC TGGCATGGAG 
CGCGAGCTGG AAAACATCAT CCAGGAGACA GAGAAGGAAC TGGACCCAGA AGGGCTGAGG 
AAGGAGTCTG AGCGGGAGCA GGCAATATTG GCTCTGACAT CCACTCTGGA CAAACTCATC 
AAGAGGCTGC AGGAGAGCCA GAGTCCAGAG CTTGTCCAGA AATACAAGAA AAGGAGAGTT 
GTCCCTCAAA AGCCTCCCCC ATCACCGCAC CCTACAGGCA AGATTGAGAT CAAAATTGTG 
CGACCCGGGG CTGAAGGTAA GGAGGAGGAC ACACGCTGGC TGACTGATGA GGACACAAGA 
AACCTTAAGG AGATTTTCTT CAATATCTTG GTGCAGGGAG CAGAAGAGGC CAATAAAGAA 
CGCCAGCGAC AGAGTGAGCT GGAGAGCAAT TACCGCCGTG TATGGGGCTC TCCGGGTGGA 
GAGGATACAG GGGACCTGGA TGAGTTTGAC TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006241523.1
CDS	51..1886
Translation	MAAEALLSSLLGLLFLGLLLPAHLTGGVGSLNLEELSEMRYGIQILPLPVMGGQSQASDVVVVSSKYKQRYECRLPAGAIHFQREREEETPAYQGPGIPELLSPMRDAPCLLKTKDWWTYEFCYGRHIQQYHMEDSEIKGDVLYLGYYQSAFNWDDETAKASKQHRLKRYHSQTYGNGSKCDLNGKPREAEVRFLCDEGAGISGDYIDRVDEPFSCSYVLSIRTSRLCPHPLLRPPASAAPQAILCHPALQPDEYMAYLQRQAESKQHEEKVTEEVQDTDHQVWSGSKAAGAPPKKEDVSPTKEDKESEFWKMLQEPEEQATGTEEAQAGEQDLNHEAAADPAPAPPTDFQNNVQVKLIRSPADLIRLIEELKGAEKGKPSVRQEQPGDDTTEAPQREAEAKGKGGEPRGLVEEEDGDEEEEDEDEDEQQLLGEFEKELEGMLLPSDRERLRSEVKAGMERELENIIQETEKELDPEGLRKESEREQAILALTSTLDKLIKRLQESQSPELVQKYKKRRVVPQKPPPSPHPTGKIEIKIVRPGAEGKEEDTRWLTDEDTRNLKEIFFNILVQGAEEANKERQRQSELESNYRRVWGSPGGEDTGDLDEFDF

Target ORF information:

RefSeq Version	XM_006241461.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus OS9, endoplasmic reticulum lectin (Os9), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006241461.1

ORF Insert Sequence:

ATGGCGGCGG AGGCGCTGCT GTCCAGTCTG TTGGGATTGC TATTTCTGGG GCTCCTGTTA 
CCTGCGCATC TGACGGGCGG TGTCGGGAGC CTGAATTTGG AGGAGCTGAG TGAGATGCGT 
TATGGCATCC AGATCCTGCC GTTGCCTGTC ATGGGAGGGC AGAGCCAAGC TTCAGACGTG 
GTGGTTGTGT CTTCAAAGTA CAAACAGCGC TATGAGTGCC GCCTACCAGC TGGAGCTATT 
CACTTCCAGC GTGAAAGGGA GGAGGAGACA CCTGCTTACC AGGGGCCCGG GATTCCTGAA 
TTGTTGAGCC CAATGAGAGA TGCCCCTTGT CTGCTGAAGA CCAAGGACTG GTGGACATAT 
GAATTCTGTT ATGGACGCCA TATCCAGCAG TACCATATGG AAGACTCGGA GATCAAAGGT 
GACGTCCTCT ACCTTGGCTA CTACCAGTCA GCCTTCAACT GGGACGATGA AACAGCCAAG 
GCCTCCAAGC AGCATCGGCT GAAACGCTAC CACAGCCAGA CCTACGGCAA TGGGTCCAAA 
TGCGATCTCA ATGGGAAGCC CAGAGAAGCT GAAGTTCGGT TCCTGTGTGA CGAGGGCGCG 
GGCATATCTG GGGACTACAT CGATCGAGTA GATGAACCCT TCTCCTGCTC CTACGTACTG 
AGCATTCGGA CATCGAGGCT CTGCCCACAC CCTCTCCTCC GCCCACCAGC CAGCGCTGCC 
CCACAGGCTA TTCTATGTCA CCCAGCCCTG CAGCCTGACG AGTACATGGC CTACCTCCAG 
AGGCAAGCTG AGTCAAAGCA GCATGAAGAG AAAGTCACAG AGGAAGTTCA GGACACAGAC 
CACCAAGTGT GGAGTGGGAG CAAGGCTGCC GGAGCACCCC CAAAGAAAGA AGATGTGAGC 
CCCACCAAGG AAGATAAGGA ATCAGAGTTT TGGAAAATGC TTCAGGAGCC AGAGGAGCAG 
GCTACAGGAA CAGAGGAAGC ACAGGCAGGG GAACAGGACC TGAACCATGA GGCTGCAGCA 
GACCCAGCTC CAGCCCCTCC CACTGATTTT CAGAATAATG TGCAGGTCAA ACTCATCCGG 
AGTCCTGCAG ATTTGATTCG ATTGATCGAG GAGCTAAAAG GTGCAGAAAA GGGGAAGCCA 
AGCGTAAGGC AGGAGCAGCC TGGAGATGAT ACCACAGAGG CCCCGCAGAG GGAAGCGGAG 
GCGAAGGGAA AGGGTGGTGA ACCCCGGGGT CTCGTGGAAG AAGAGGATGG TGACGAGGAG 
GAGGAGGACG AGGACGAGGA TGAGCAGCAG CTCCTGGGAG AGTTCGAGAA GGAGTTGGAG 
GGGATGCTGC TGCCCTCGGA CCGAGAGCGC CTGCGCTCAG AGGTTAAGGC TGGCATGGAG 
CGCGAGCTGG AAAACATCAT CCAGGAGACA GAGAAGGAAC TGGACCCAGA AGGGCTGAGG 
AAGGAGTCTG AGCGGGAGCA GGCAATATTG GCTCTGACAT CCACTCTGGA CAAACTCATC 
AAGAGGCTGC AGGAGAGCCA GAGTCCAGAG CTTGTCCAGA AATACAAGAA AAGGAGAGTT 
GTCCCTCAAA AGCCTCCCCC ATCACCGCAC CCTACAGGCA AGATTGAGAT CAAAATTGTG 
CGACCCGGGG CTGAAGGTAA GGAGGAGGAC ACACGCTGGC TGACTGATGA GGACACAAGA 
AACCTTAAGG AGATTTTCTT CAATATCTTG GTGCAGGGAG CAGAAGAGGC CAATAAAGAA 
CGCCAGCGAC AGAGTGAGCT GGAGAGCAAT TACCGCCGTG TATGGGGCTC TCCGGGTGGA 
GAGGATACAG GGGACCTGGA TGAGTTTGAC TTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Identification of ERAD components essential for dislocation of the null Hong Kong variant of ?-1-antitrypsin (NHK).
Biochemical and biophysical research communications458(2)424-8(2015 Mar)
Zhong Y,Shen H,Wang Y,Yang Y,Yang P,Fang S

SEL1L protein critically determines the stability of the HRD1-SEL1L endoplasmic reticulum-associated degradation (ERAD) complex to optimize the degradation kinetics of ERAD substrates.
The Journal of biological chemistry286(19)16929-39(2011 May)
Iida Y,Fujimori T,Okawa K,Nagata K,Wada I,Hosokawa N

Human OS-9, a lectin required for glycoprotein endoplasmic reticulum-associated degradation, recognizes mannose-trimmed N-glycans.
The Journal of biological chemistry284(25)17061-8(2009 Jun)
Hosokawa N,Kamiya Y,Kamiya D,Kato K,Nagata K

Regulation of oxygen homeostasis by hypoxia-inducible factor 1.
Physiology (Bethesda, Md.)2497-106(2009 Apr)
Semenza GL

[The cooperation of OS-9 and PHDs in hypoxia-induced pulmonary hypertension of rats].
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology25(1)1-6(2009 Feb)
Pan K,Dai AG,Hu RC

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Os9 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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