Reep6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Reep6
Entrez Gene ID	362835
Full Name	receptor accessory protein 6
Synonyms	Dp1l1
General protein information	Preferred Names receptor accessory protein 6 Names receptor expression-enhancing protein 6 deleted in polyposis 1-like 1 polyposis locus protein 1-like 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q11

mRNA and Protein(s)

mRNA	Protein	Name
NM_001013218.1	NP_001013236.1	receptor expression-enhancing protein 6
XM_006240967.3	XP_006241029.2	receptor expression-enhancing protein 6 isoform X1

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	reep6	NP_001004656.1
Xenopus tropicalis (tropical clawed frog)	reep6	NP_001016051.1
Homo sapiens (human)	REEP6	NP_612402.1
Bos taurus (cattle)	REEP6	NP_001033224.1
Gallus gallus (chicken)	REEP6	XP_424848.4
Danio rerio (zebrafish)	LOC100536786	XP_005172894.1
	REEP6	XP_001095757.1
Mus musculus (house mouse)	Reep6	NP_647453.1
Rattus norvegicus (Norway rat)	Reep6	NP_001013236.1

Gene Ontology
Bibliography

Related articles in PubMed

Mutations in REEP6 Cause Autosomal-Recessive Retinitis Pigmentosa.
Arno G, Agrawal SA, Eblimit A, Bellingham J, Xu M, Wang F, Chakarova C, Parfitt DA, Lane A, Burgoyne T, Hull S, Carss KJ, Fiorentino A, Hayes MJ, Munro PM, Nicols R, Pontikos N, Holder GE, , Asomugha C, Raymond FL, Moore AT, Plagnol V, Michaelides M, Hardcastle AJ, Li Y, Cukras C, Webster AR, Cheetham ME, Chen R
American journal of human genetics99(6)1305-1315(2016 Dec)

Regulation of a novel isoform of Receptor Expression Enhancing Protein REEP6 in rod photoreceptors by bZIP transcription factor NRL.
Hao H, Veleri S, Sun B, Kim DS, Keeley PW, Kim JW, Yang HJ, Yadav SP, Manjunath SH, Sood R, Liu P, Reese BE, Swaroop A
Human molecular genetics23(16)4260-71(2014 Aug)

REEPs are membrane shaping adapter proteins that modulate specific g protein-coupled receptor trafficking by affecting ER cargo capacity.
Bj?rk S, Hurt CM, Ho VK, Angelotti T
PloS one8(10)e76366(2013)

Ascl1 (Mash1) knockout perturbs differentiation of nonneuronal cells in olfactory epithelium.
Krolewski RC, Packard A, Jang W, Wildner H, Schwob JE
PloS one7(12)e51737(2012)

Proteomic characterization of the human sperm nucleus.
de Mateo S, Castillo J, Estanyol JM, Ballesc? JL, Oliva R
Proteomics11(13)2714-26(2011 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

TB2-like 1 is a membrane protein that belongs to the YOP1/TB2/DP1/HVA22 family, and it probably plays an important role in intracellular membrane trafficking in RGCs
Title: Deleted in polyposis 1-like 1 gene (Dp1l1): a novel gene richly expressed in retinal ganglion cells.

The following Reep6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Reep6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa03838	NM_001013218.1 Latest version!	Rattus norvegicus receptor accessory protein 6 (Reep6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa62037	XM_006240967.3 Latest version!	Rattus norvegicus receptor accessory protein 6 (Reep6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Reep6 ( NM_001013218.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001013236.1 Rattus norvegicus receptor accessory protein 6 (Reep6), mRNA.

Price & Availability↑

CloneID	ORa03838
Clone ID Related Accession (Same CDS sequence)	NM_001013218.1
Accession Version	NM_001013218.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 636bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-09-15
Organism	Rattus norvegicus(Norway rat)
Product	receptor expression-enhancing protein 6
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC083830.1. On Apr 20, 2005 this sequence version replaced XM_343163.2. ##Evidence-Data-START## Transcript exon combination :: BC083830.1, CK469420.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGACGGTC TGCGCCAGCG CTTCGAACGT TTTCTGGAAC AGAAGAACGT GGCCACCGAC 
GCGCTGGGGG CGCTCGAAGC CAGGACCGGT GTAGAGAAGC GGTATCTCGC CGCGGGAGCC 
CTCACCCTTC TAGGCCTGTA TCTTCTGTTC GGCTACGGGG CGTCTCTACT TTGCAATGTC 
ATCGGATTTG TATACCCCGC ATATGCTTCA GTCAAAGCTA TCGAGAGCCC AAACAAGGAA 
GACGACACTG TGTGGCTAAC CTACTGGGTG GTGTACGCCC TGTTCGGTCT AGTCGAGTTC 
TTCAGCGATC TACTCCTGTT CTGGTTCCCT TTCTACTACG CGGGCAAGTG CGCCTTCCTA 
TTATTTTGCA TGACACCCGG GCCCTGGAAC GGGGCATTGC TACTGTATCA TCGCGTCATA 
AGACCTCTGT TTCTAAAGCA CCACGTGGCT CTAGACAGCG CCGCGAGCCA GCTAAGCGGA 
AGAGCATTGG ACATAGCAGC TGGGATAACC AGGGACGTGC TACAGGCCTT GGCTCGGGGT 
CGGACTCTCG TAACCCCAGC ATCAGCATCG GAGTCCCCAG CCGCTCTGGA ACCGGACCCC 
AAGTCAAGTC AGACCACACT CCTGAAGCAC AAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001013236.1
CDS	28..663
Translation	MDGLRQRFERFLEQKNVATDALGALEARTGVEKRYLAAGALTLLGLYLLFGYGASLLCNVIGFVYPAYASVKAIESPNKEDDTVWLTYWVVYALFGLVEFFSDLLLFWFPFYYAGKCAFLLFCMTPGPWNGALLLYHRVIRPLFLKHHVALDSAASQLSGRALDIAAGITRDVLQALARGRTLVTPASASESPAALEPDPKSSQTTLLKHK

Target ORF information:

RefSeq Version	NM_001013218.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus receptor accessory protein 6 (Reep6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001013218.1

ORF Insert Sequence:

ATGGACGGTC TGCGCCAGCG CTTCGAACGT TTTCTGGAAC AGAAGAACGT GGCCACCGAC 
GCGCTGGGGG CGCTCGAAGC CAGGACCGGT GTAGAGAAGC GGTATCTCGC CGCGGGAGCC 
CTCACCCTTC TAGGCCTGTA TCTTCTGTTC GGCTACGGGG CGTCTCTACT TTGCAATGTC 
ATCGGATTTG TATACCCCGC ATATGCTTCA GTCAAAGCTA TCGAGAGCCC AAACAAGGAA 
GACGACACTG TGTGGCTAAC CTACTGGGTG GTGTACGCCC TGTTCGGTCT AGTCGAGTTC 
TTCAGCGATC TACTCCTGTT CTGGTTCCCT TTCTACTACG CGGGCAAGTG CGCCTTCCTA 
TTATTTTGCA TGACACCCGG GCCCTGGAAC GGGGCATTGC TACTGTATCA TCGCGTCATA 
AGACCTCTGT TTCTAAAGCA CCACGTGGCT CTAGACAGCG CCGCGAGCCA GCTAAGCGGA 
AGAGCATTGG ACATAGCAGC TGGGATAACC AGGGACGTGC TACAGGCCTT GGCTCGGGGT 
CGGACTCTCG TAACCCCAGC ATCAGCATCG GAGTCCCCAG CCGCTCTGGA ACCGGACCCC 
AAGTCAAGTC AGACCACACT CCTGAAGCAC AAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Reep6 ( XM_006240967.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006241029.2 Rattus norvegicus receptor accessory protein 6 (Reep6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa62037
Clone ID Related Accession (Same CDS sequence)	XM_006240967.3
Accession Version	XM_006240967.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 555bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	receptor expression-enhancing protein 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006240967.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACGGTC TGCGCCAGCG CTTCGAACGT TTTCTGGAAC AGAAGAACGT GGCCACCGAC 
GCGCTGGGGG CGCTCGAAGC CAGGACCGGT GTAGAGAAGC GGTATCTCGC CGCGGGAGCC 
CTCACCCTTC TAGGCCTGTA TCTTCTGTTC GGCTACGGGG CGTCTCTACT TTGCAATGTC 
ATCGGATTTG TATACCCCGC ATATGCTTCA GTCAAAGCTA TCGAGAGCCC AAACAAGGAA 
GACGACACTG TGTGGCTAAC CTACTGGGTG GTGTACGCCC TGTTCGGTCT AGTCGAGTTC 
TTCAGCGATC TACTCCTGTT CTGGTTCCCT TTCTACTACG CGGGCAAGTG CGCCTTCCTA 
TTATTTTGCA TGACACCCGG GCCCTGGAAC GGGGCATTGC TACTGTATCA TCGCGTCATA 
AGACCTCTGT TTCTAAAGCA CCACGTGGCT CTAGACAGCG CCGCGAGCCA GCTAAGCGGA 
AGAGCATTGG ACATAGCAGC TGGGATAACC AGGGACGCCA AGTCAAGTCA GACCACACTC 
CTGAAGCACA AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006241029.2
CDS	113..667
Translation	MDGLRQRFERFLEQKNVATDALGALEARTGVEKRYLAAGALTLLGLYLLFGYGASLLCNVIGFVYPAYASVKAIESPNKEDDTVWLTYWVVYALFGLVEFFSDLLLFWFPFYYAGKCAFLLFCMTPGPWNGALLLYHRVIRPLFLKHHVALDSAASQLSGRALDIAAGITRDAKSSQTTLLKHK

Target ORF information:

RefSeq Version	XM_006240967.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus receptor accessory protein 6 (Reep6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006240967.3

ORF Insert Sequence:

ATGGACGGTC TGCGCCAGCG CTTCGAACGT TTTCTGGAAC AGAAGAACGT GGCCACCGAC 
GCGCTGGGGG CGCTCGAAGC CAGGACCGGT GTAGAGAAGC GGTATCTCGC CGCGGGAGCC 
CTCACCCTTC TAGGCCTGTA TCTTCTGTTC GGCTACGGGG CGTCTCTACT TTGCAATGTC 
ATCGGATTTG TATACCCCGC ATATGCTTCA GTCAAAGCTA TCGAGAGCCC AAACAAGGAA 
GACGACACTG TGTGGCTAAC CTACTGGGTG GTGTACGCCC TGTTCGGTCT AGTCGAGTTC 
TTCAGCGATC TACTCCTGTT CTGGTTCCCT TTCTACTACG CGGGCAAGTG CGCCTTCCTA 
TTATTTTGCA TGACACCCGG GCCCTGGAAC GGGGCATTGC TACTGTATCA TCGCGTCATA 
AGACCTCTGT TTCTAAAGCA CCACGTGGCT CTAGACAGCG CCGCGAGCCA GCTAAGCGGA 
AGAGCATTGG ACATAGCAGC TGGGATAACC AGGGACGCCA AGTCAAGTCA GACCACACTC 
CTGAAGCACA AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mutations in REEP6 Cause Autosomal-Recessive Retinitis Pigmentosa.
American journal of human genetics99(6)1305-1315(2016 Dec)
Arno G,Agrawal SA,Eblimit A,Bellingham J,Xu M,Wang F,Chakarova C,Parfitt DA,Lane A,Burgoyne T,Hull S,Carss KJ,Fiorentino A,Hayes MJ,Munro PM,Nicols R,Pontikos N,Holder GE,,Asomugha C,Raymond FL,Moore AT,Plagnol V,Michaelides M,Hardcastle AJ,Li Y,Cukras C,Webster AR,Cheetham ME,Chen R

Regulation of a novel isoform of Receptor Expression Enhancing Protein REEP6 in rod photoreceptors by bZIP transcription factor NRL.
Human molecular genetics23(16)4260-71(2014 Aug)
Hao H,Veleri S,Sun B,Kim DS,Keeley PW,Kim JW,Yang HJ,Yadav SP,Manjunath SH,Sood R,Liu P,Reese BE,Swaroop A

REEPs are membrane shaping adapter proteins that modulate specific g protein-coupled receptor trafficking by affecting ER cargo capacity.
PloS one8(10)e76366(2013)
Bj?rk S,Hurt CM,Ho VK,Angelotti T

Ascl1 (Mash1) knockout perturbs differentiation of nonneuronal cells in olfactory epithelium.
PloS one7(12)e51737(2012)
Krolewski RC,Packard A,Jang W,Wildner H,Schwob JE

Proteomic characterization of the human sperm nucleus.
Proteomics11(13)2714-26(2011 Jul)
de Mateo S,Castillo J,Estanyol JM,Ballesc? JL,Oliva R

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Reep6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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