Dot1l cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Dot1l
Entrez Gene ID	362831
Full Name	DOT1 like histone lysine methyltransferase
General protein information	Preferred Names DOT1 like histone lysine methyltransferase Names histone-lysine N-methyltransferase, H3 lysine-79 specific DOT1-like histone H3K79 methyltransferase DOT1-like, histone H3 methyltransferase
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q11

mRNA and Protein(s)

mRNA	Protein	Name
XM_017594910.1	XP_017450399.1	histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X3
XM_006240961.3	XP_006241023.1	histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X2
NM_001108733.1	NP_001102203.1	histone-lysine N-methyltransferase, H3 lysine-79 specific
XM_006240960.3	XP_006241022.1	histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
XM_006240959.3	XP_006241021.1	histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	DOT1L	XP_003953365.1
Canis lupus familiaris (dog)	DOT1L	XP_005633296.1
Homo sapiens (human)	DOT1L	NP_115871.1
	DOT1L	XP_001097213.2
Xenopus tropicalis (tropical clawed frog)	dot1l	XP_002937984.2
Bos taurus (cattle)	DOT1L	XP_005209126.1
Mus musculus (house mouse)	Dot1l	NP_955354.1
Rattus norvegicus (Norway rat)	Dot1l	NP_001102203.1
Gallus gallus (chicken)	DOT1L	XP_004948823.1
Danio rerio (zebrafish)	dot1l	XP_005170590.1

Gene Ontology
Bibliography

Related articles in PubMed

Potent inhibition of DOT1L as treatment of MLL-fusion leukemia.
Daigle SR, Olhava EJ, Therkelsen CA, Basavapathruni A, Jin L, Boriack-Sjodin PA, Allain CJ, Klaus CR, Raimondi A, Scott MP, Waters NJ, Chesworth R, Moyer MP, Copeland RA, Richon VM, Pollock RM
Blood122(6)1017-25(2013 Aug)

Histone lysine methylation dynamics: establishment, regulation, and biological impact.
Black JC, Van Rechem C, Whetstine JR
Molecular cell48(4)491-507(2012 Nov)

Targeting protein lysine methylation and demethylation in cancers.
He Y, Korboukh I, Jin J, Huang J
Acta biochimica et biophysica Sinica44(1)70-9(2012 Jan)

A novel disrupter of telomere silencing 1-like (DOT1L) interaction is required for signal transducer and activator of transcription 1 (STAT1)-activated gene expression.
Shah S, Henriksen MA
The Journal of biological chemistry286(48)41195-204(2011 Dec)

Modulation of p53 function by SET8-mediated methylation at lysine 382.
Shi X, Kachirskaia I, Yamaguchi H, West LE, Wen H, Wang EW, Dutta S, Appella E, Gozani O
Molecular cell27(4)636-46(2007 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Dot1l gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dot1l cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa42257	NM_001108733.1 Latest version!	Rattus norvegicus DOT1 like histone lysine methyltransferase (Dot1l), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$1140.30 $1629.00
ORa29887	XM_006240961.3 Latest version!	Rattus norvegicus DOT1 like histone lysine methyltransferase (Dot1l), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$811.30 $1159.00
ORa29886	XM_006240960.3 Latest version!	Rattus norvegicus DOT1 like histone lysine methyltransferase (Dot1l), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$951.30 $1359.00
ORa29886	XM_006240959.3 Latest version!	Rattus norvegicus DOT1 like histone lysine methyltransferase (Dot1l), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$951.30 $1359.00
ORa62036	XM_017594910.1 Latest version!	Rattus norvegicus DOT1 like histone lysine methyltransferase (Dot1l), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$811.30 $1159.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Dot1l ( NM_001108733.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001102203.1 Rattus norvegicus DOT1 like histone lysine methyltransferase (Dot1l), mRNA.

Price & Availability↑

CloneID	ORa42257
Clone ID Related Accession (Same CDS sequence)	NM_001108733.1
Accession Version	NM_001108733.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4650bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	histone-lysine N-methyltransferase, H3 lysine-79 specific
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH474029.1. On or before Oct 4, 2007 this sequence version replaced XM_343159.3, XM_001071372.1.

ATGGGCGAGA AGCTGGAGCT GAGGCTCAAG TCGCCTGTGG GCGCGGAGCC CGCCGTCTAC 
CCGTGGCCGC TGCCGGTCTA CGTGAGTGTA CTTGCGGAGA ACCCGGGGGA CAAGCACCAT 
GATGCTGCTC ATGAGATTAT CGAGACTATC CGATGGGTCT GCGAGGAAAT CCCAGATCTC 
AAGCTGGCCA TGGAGAACTA TGTCCTGATC GACTACGACA CCAAAAGTTT TGAAAGCATG 
CAGAGGCTGT GTGACAAATA TAACCGGGCC ATTGACAGCA TCCACCAGCT GTGGAAGGGC 
ACTACACAGC CCATGAAGCT CAATACTCGG CCGTCCAATG GGCTCCTGCG GCACATCCTG 
CAGCAGGTGT ACAACCACTC TGTGACCGAC CCAGAGAAGC TCAACAACTA CGAGCCCTTC 
TCCCCCGAGG TGTACGGGGA GACCTCCTTT GACCTGGTGG CCCAGATGAT CGATGAGATC 
AAGATGACCG AGGATGACCT GTTTGTAGAC CTGGGCAGTG GTGTGGGGCA GGTTGTCCTT 
CAGGTTGCGG CGGCCACCAA CTGCAAACAT CACTACGGAG TGGAGAAAGC GGACATCCCA 
GCCAAGTACG CGGAGACCAT GGATCGAGAG TTCAGGAAGT GGATGAAATG GTATGGAAAA 
AAGCATGCAG AATACACACT GGAGCGAGGT GACTTCCTCT CAGAGGAGTG GAGGGAACGG 
ATCGCCAACA CGAGTGTTAT ATTTGTGAAT AACTTTGCCT TTGGTCCTGA GGTGGATCAC 
CAGCTGAAGG AACGATTCGC AAACATGAAG GAAGGCGGCA GAATCGTATC CTCAAAGCCC 
TTTGCCCCTC TGAACTTCAG GATCAACAGC AGGAACTTGA GTGACATTGG CACCATCATG 
CGTGTGGTGG AGCTGTCGCC CCTGAAGGGC TCTGTGTCAT GGACTGGCAA GCCTGTCTCC 
TACTACCTGC ACACCATTGA CCGCACCATA CTTGAAAACT ATTTTTCTAG TCTGAAAAAT 
CCAAAACTCA GGGAGGAGCA GGAGGCAGCT AGGCGCAGGC AGCAGCGAGA GAACAAGAGC 
AACGCGACCA CACCCACCAA AGTCCCTGAG AGCAAGGCAG CTGCCACCGA GGCCCCTGCG 
GATTCTGGTG CTGAGGAAGA AAAATCAGGT GTGGCCACCG TCAAAAAGCA ATCTCCCTCC 
AAAGCCCGGA AGAAGAAACT GAACAAGAAA GGGAGAAAAA TGGCTGGCCG GAAGCGTGGG 
CGACCCAAGA AAATGAGTGC TGCCAGTGCC GATCGCAAGT CCAAGAAGAG CCAAAGCACA 
CTGGATCTCC TGCACTCTCC GCCCCCAGCC CCACCCTCAG CCTCACCCCA GGATGCATAC 
AGGGCCCCCC ACAGCCCGTT CTACCAGCTA CCTCCGAGCA CGCCGCTGCA CTCGCCCGAC 
CCACTGCTAG TGGCTCCCAC CCCACCCGCG CTGCAGAAGC TGTTAGAGTC CTTCAAGATC 
CAGTACCTGC AGTTCCTGGC CTACACGAAG ACCCCGCAGT ACAAGGCCAA CCTGCAGCAG 
CTTCTGGACC AGGAGAAGGA GAAGAACACA CAACTGCTGG GTACAGCCCA GCAGCTCTTC 
AGCCATTGCC AGGCACAAAA GGAAGAGATC CGCAGGCTGT TCCAGCAGAA GCTGGATGAG 
TTGGGCGTGA AGGCACTGAC CTACAATGAC CTGATTCAGG CCCAGAAGGA AATCTCTGCC 
CACAACCAGC AGCTGCGGGA GCAGTCGGAA CAGCTGGAGA AGGACAACAG CGAGCTTCGG 
AGCCAGAGCC TGCGGCTGCT CAGGGCCCGG TGCGAAGAGC TGAGGCTTGA CTGGTCCACC 
TTGTCCCTGG AGAACCTGCG GAAAGAGAAG CAGGCCCTGC GGAGCCAGAT CTCAGAGAAG 
CAGCGGCACT GCCTAGAGCT GCAGATCAGC ATCGTGGAGC TGGAGAAGAC CCAGCGCCAG 
CAGGAGCTCC TGCAGTTGAA GTCCTGTGTG CCACCAGATG ACGCTCTGTC CCTGCACCTG 
CGTGGCAAGG GTGCCCTGGG CCGCGAGCTG GAGTCTGACG CTGGGCGCTT GCGCCTTGAG 
CTGGACTGTG CCAAGCTCTC CCTCCCACAC CTCAGCAGCA TGAGCCCTGA GCTGTCCATG 
AATGGCCATG CCGCCAGCTA TGAGCTCTGC GGTGCAGCTA GTCGGCCCTC GTCCAAGCAG 
AACACCCCCC AGTATCTGGC CTCCCCCTTG GACCAGGAGG TCGTGCCCTG CACCCCTAGC 
CACAGTGGCC GGCCTCGGCT GGAGAAGCTG TCTGGCCTGG CTTTGCCTGA CTACACCCGG 
TTGTCACCGG CCAAGATTGT GTTGAGGCGG CACCTGAGCC AGGACCACAC CGGGGCCAGC 
AAAGCAGCTA CTAGTGAGCC ACACCCTCGG CCAGAGCATG CCAAGGAGAA CAGCCTTCCC 
TACCAGAGCC CTGGCTTGTC GAACAGCATG AAGCTCAGCC CCCAGGATCC ACCGCTGGCC 
TCCCCGGCAA CCTCACCCCT CACTTCCGAG AGGGGTAGTG AGAAGGGTGT AAAGGAGCGT 
GCCTACAGCA GCCATGGGGA GACCATCACC AGCCTGCCTG TCAGCATTCC ACTCAGCACA 
GTACAGCCCA ACAAGCTGCC TGTCAGCATC CCGCTAGCCA GCGTGGTGCT GCCCAGCCGT 
GCCGAGAGGG CGAGGAGCAC TCCCAGCCCT GTGCCCCAGC CTCGAGACTC CTCATCCACA 
CTTGAGAAGC AGATTGGTGC TTCCACCCAT GGTGCAGGGG GTGCTGCGGC AGGAAGCAGG 
AGCCTCACTG TGGCGCCCAC AGGTTTCTAT GCTGGTTCGG TGGCCATCAG TGGGGCTCTG 
GCCAGCAGCC CAGCACCTCT GGCCTCTGGA ATGGAATCTG CTGTTTTTGA GGAGTCCTCT 
GGCCCCAGCA GCCTCTTTGG CACCATGGGG TCTCGCAGCA CACCGCCACA ACATCCACCT 
CTCCTGCCGC AGTCTCGCAA CTCGGGCCCT GCCTCTCCTG CCCACCAGCT CGCAGCCAGT 
CCCCGCCTGA GTGTGACCAC CCAGGGCTCA CTGCCAGACA CCGGCAAAGG GGAGCTGCCT 
GCTGATCCTG CCTTCTCAGA CCCAGAGAGT GAAGCTAAGA GGAGGATTGT GTTCAGCATT 
TCAGCTGGTG CCAGCTCCAG GCAGTCGCCT TCCACCAGGC ACAGCCCCTT GACCTCTGGC 
ACCCGTGGGG ATTGTGTTCA GAGCCATGGG CAGGACAGTC GTAAGCGTAG CAGAAGGAAG 
CGTGCATCAG CTGGAACGCC TAGCCTCACC ACGGGTGTGT CCCCCAAGCG CCGAGCTCTG 
CCAACCGTCG CTGGCCTCTT TACACAGTCT TCGGGGTCGC CTCTCAATCT CACCTCCATG 
GTCAGCAACA TCAACCAGCC CCTGGAGATC ACAGCCATCT CATCCCCGGA GAGCTCACTG 
AAGAGCTCCC CCACACCCTA CCAGGACCAT GACCAGCCTC CAGTGCTCAG GAAGGAGCGG 
CCCCTGGGCC CAACTAATGG GGCCCACTAC TCTCCGCTGA CGTCAGATGA GGAGCCAGGC 
TCGGAGGACG AGCCCAGCAG TGCCCGAATT GAGAGAAAAA TTGCAACAAT CTCTTTAGAA 
AGCAAATCTC CCCCGAAGAC ACTGGAAAAT GGTGGTGGCT TAGTGGGAAG GAAGCCGGTC 
CCCTCAGGCG AGCCTGTCAA CAGCAGCAAA TGGAAGTCCA CCTTCTCACC CATCTCCGAC 
CTCGGCTTGG CCAAGGCCAT GGACAGTCCG CTACAGGCCA GCTCTGCACT GAGCCACAGC 
CCCCTCTTCT CTTTCCGGCC GTCCTTGGAG GAGCCTGCTG CTGAGGCCAA GCCCTCCACC 
CACCCAAGGA AAAGTTTTGC GGGCTCTCTG GCTGCAGCTG AGGGGCCAAG CCCTGGCACC 
AACCCTCCCA ACAGCCTGGC CTTCAGTGGG GGCCTTGCTG CAGACCTCGG TTTACATAGC 
TTCAATGACG GTGCTTCCCT CTCCCACAAG GGCCCGGAGG TGGCGGGCCT GAGCGCCTCC 
CTGAGCTTCC CATCCCAGAG GGGCAAGGAC AGTACCACAG AGGCCAACCC CTTCCTCAGC 
AGGCGGCAGC CGGAGGGCCT GGGTGGCCTG AAGGGTGAGG GCAATGCAAG CAAGGAGTCA 
GGAGAGAGCC TGCCCCTGTG TGGGCCCTCA GACAAGGTCT CACTGCCACA CGGCAGCAGG 
GCCAGCAAAG GCCGTGACCG CGAGCTGGAC TTCAAGGGCG GCCACAACCT CTTCATCTCT 
GCTGCAGCCG TGCCTCCAGG TGGCCTCCTT GGTGGCCCTG GTCTTGTAAC TGTGGCTTCC 
TCTGCGGGCA GTGCGACACC CTCTGCCCAG GCTCCCCGGC CTTTCCTGAG CACCTTTGCC 
CCTGGGCCCC AGTTTACTCT GGGCCCCATG TCCCTGCAGG CCAACCTGGG CTCTGTGGCC 
GGCTCCTCTG TGCTGCAGTC CTTGTTCAGC ACTGTGCCAG CTGCTGCAGG CCTGGTGCAT 
GTGTCATCCA CTGCGACCCG ACTGACCAAC TCACACACCA TGGGCAGCTT CTCCTCTGGG 
GTGGCCGGCG GAACCGTTGG AGGTAATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001102203.1
CDS	240..4889
Translation	MGEKLELRLKSPVGAEPAVYPWPLPVYVSVLAENPGDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNATTPTKVPESKAAATEAPADSGAEEEKSGVATVKKQSPSKARKKKLNKKGRKMAGRKRGRPKKMSAASADRKSKKSQSTLDLLHSPPPAPPSASPQDAYRAPHSPFYQLPPSTPLHSPDPLLVAPTPPALQKLLESFKIQYLQFLAYTKTPQYKANLQQLLDQEKEKNTQLLGTAQQLFSHCQAQKEEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEKDNSELRSQSLRLLRARCEELRLDWSTLSLENLRKEKQALRSQISEKQRHCLELQISIVELEKTQRQQELLQLKSCVPPDDALSLHLRGKGALGRELESDAGRLRLELDCAKLSLPHLSSMSPELSMNGHAASYELCGAASRPSSKQNTPQYLASPLDQEVVPCTPSHSGRPRLEKLSGLALPDYTRLSPAKIVLRRHLSQDHTGASKAATSEPHPRPEHAKENSLPYQSPGLSNSMKLSPQDPPLASPATSPLTSERGSEKGVKERAYSSHGETITSLPVSIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPSPVPQPRDSSSTLEKQIGASTHGAGGAAAGSRSLTVAPTGFYAGSVAISGALASSPAPLASGMESAVFEESSGPSSLFGTMGSRSTPPQHPPLLPQSRNSGPASPAHQLAASPRLSVTTQGSLPDTGKGELPADPAFSDPESEAKRRIVFSISAGASSRQSPSTRHSPLTSGTRGDCVQSHGQDSRKRSRRKRASAGTPSLTTGVSPKRRALPTVAGLFTQSSGSPLNLTSMVSNINQPLEITAISSPESSLKSSPTPYQDHDQPPVLRKERPLGPTNGAHYSPLTSDEEPGSEDEPSSARIERKIATISLESKSPPKTLENGGGLVGRKPVPSGEPVNSSKWKSTFSPISDLGLAKAMDSPLQASSALSHSPLFSFRPSLEEPAAEAKPSTHPRKSFAGSLAAAEGPSPGTNPPNSLAFSGGLAADLGLHSFNDGASLSHKGPEVAGLSASLSFPSQRGKDSTTEANPFLSRRQPEGLGGLKGEGNASKESGESLPLCGPSDKVSLPHGSRASKGRDRELDFKGGHNLFISAAAVPPGGLLGGPGLVTVASSAGSATPSAQAPRPFLSTFAPGPQFTLGPMSLQANLGSVAGSSVLQSLFSTVPAAAGLVHVSSTATRLTNSHTMGSFSSGVAGGTVGGN

Target ORF information:

RefSeq Version	NM_001108733.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus DOT1 like histone lysine methyltransferase (Dot1l), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108733.1

ORF Insert Sequence:

ATGGGCGAGA AGCTGGAGCT GAGGCTCAAG TCGCCTGTGG GCGCGGAGCC CGCCGTCTAC 
CCGTGGCCGC TGCCGGTCTA CGTGAGTGTA CTTGCGGAGA ACCCGGGGGA CAAGCACCAT 
GATGCTGCTC ATGAGATTAT CGAGACTATC CGATGGGTCT GCGAGGAAAT CCCAGATCTC 
AAGCTGGCCA TGGAGAACTA TGTCCTGATC GACTACGACA CCAAAAGTTT TGAAAGCATG 
CAGAGGCTGT GTGACAAATA TAACCGGGCC ATTGACAGCA TCCACCAGCT GTGGAAGGGC 
ACTACACAGC CCATGAAGCT CAATACTCGG CCGTCCAATG GGCTCCTGCG GCACATCCTG 
CAGCAGGTGT ACAACCACTC TGTGACCGAC CCAGAGAAGC TCAACAACTA CGAGCCCTTC 
TCCCCCGAGG TGTACGGGGA GACCTCCTTT GACCTGGTGG CCCAGATGAT CGATGAGATC 
AAGATGACCG AGGATGACCT GTTTGTAGAC CTGGGCAGTG GTGTGGGGCA GGTTGTCCTT 
CAGGTTGCGG CGGCCACCAA CTGCAAACAT CACTACGGAG TGGAGAAAGC GGACATCCCA 
GCCAAGTACG CGGAGACCAT GGATCGAGAG TTCAGGAAGT GGATGAAATG GTATGGAAAA 
AAGCATGCAG AATACACACT GGAGCGAGGT GACTTCCTCT CAGAGGAGTG GAGGGAACGG 
ATCGCCAACA CGAGTGTTAT ATTTGTGAAT AACTTTGCCT TTGGTCCTGA GGTGGATCAC 
CAGCTGAAGG AACGATTCGC AAACATGAAG GAAGGCGGCA GAATCGTATC CTCAAAGCCC 
TTTGCCCCTC TGAACTTCAG GATCAACAGC AGGAACTTGA GTGACATTGG CACCATCATG 
CGTGTGGTGG AGCTGTCGCC CCTGAAGGGC TCTGTGTCAT GGACTGGCAA GCCTGTCTCC 
TACTACCTGC ACACCATTGA CCGCACCATA CTTGAAAACT ATTTTTCTAG TCTGAAAAAT 
CCAAAACTCA GGGAGGAGCA GGAGGCAGCT AGGCGCAGGC AGCAGCGAGA GAACAAGAGC 
AACGCGACCA CACCCACCAA AGTCCCTGAG AGCAAGGCAG CTGCCACCGA GGCCCCTGCG 
GATTCTGGTG CTGAGGAAGA AAAATCAGGT GTGGCCACCG TCAAAAAGCA ATCTCCCTCC 
AAAGCCCGGA AGAAGAAACT GAACAAGAAA GGGAGAAAAA TGGCTGGCCG GAAGCGTGGG 
CGACCCAAGA AAATGAGTGC TGCCAGTGCC GATCGCAAGT CCAAGAAGAG CCAAAGCACA 
CTGGATCTCC TGCACTCTCC GCCCCCAGCC CCACCCTCAG CCTCACCCCA GGATGCATAC 
AGGGCCCCCC ACAGCCCGTT CTACCAGCTA CCTCCGAGCA CGCCGCTGCA CTCGCCCGAC 
CCACTGCTAG TGGCTCCCAC CCCACCCGCG CTGCAGAAGC TGTTAGAGTC CTTCAAGATC 
CAGTACCTGC AGTTCCTGGC CTACACGAAG ACCCCGCAGT ACAAGGCCAA CCTGCAGCAG 
CTTCTGGACC AGGAGAAGGA GAAGAACACA CAACTGCTGG GTACAGCCCA GCAGCTCTTC 
AGCCATTGCC AGGCACAAAA GGAAGAGATC CGCAGGCTGT TCCAGCAGAA GCTGGATGAG 
TTGGGCGTGA AGGCACTGAC CTACAATGAC CTGATTCAGG CCCAGAAGGA AATCTCTGCC 
CACAACCAGC AGCTGCGGGA GCAGTCGGAA CAGCTGGAGA AGGACAACAG CGAGCTTCGG 
AGCCAGAGCC TGCGGCTGCT CAGGGCCCGG TGCGAAGAGC TGAGGCTTGA CTGGTCCACC 
TTGTCCCTGG AGAACCTGCG GAAAGAGAAG CAGGCCCTGC GGAGCCAGAT CTCAGAGAAG 
CAGCGGCACT GCCTAGAGCT GCAGATCAGC ATCGTGGAGC TGGAGAAGAC CCAGCGCCAG 
CAGGAGCTCC TGCAGTTGAA GTCCTGTGTG CCACCAGATG ACGCTCTGTC CCTGCACCTG 
CGTGGCAAGG GTGCCCTGGG CCGCGAGCTG GAGTCTGACG CTGGGCGCTT GCGCCTTGAG 
CTGGACTGTG CCAAGCTCTC CCTCCCACAC CTCAGCAGCA TGAGCCCTGA GCTGTCCATG 
AATGGCCATG CCGCCAGCTA TGAGCTCTGC GGTGCAGCTA GTCGGCCCTC GTCCAAGCAG 
AACACCCCCC AGTATCTGGC CTCCCCCTTG GACCAGGAGG TCGTGCCCTG CACCCCTAGC 
CACAGTGGCC GGCCTCGGCT GGAGAAGCTG TCTGGCCTGG CTTTGCCTGA CTACACCCGG 
TTGTCACCGG CCAAGATTGT GTTGAGGCGG CACCTGAGCC AGGACCACAC CGGGGCCAGC 
AAAGCAGCTA CTAGTGAGCC ACACCCTCGG CCAGAGCATG CCAAGGAGAA CAGCCTTCCC 
TACCAGAGCC CTGGCTTGTC GAACAGCATG AAGCTCAGCC CCCAGGATCC ACCGCTGGCC 
TCCCCGGCAA CCTCACCCCT CACTTCCGAG AGGGGTAGTG AGAAGGGTGT AAAGGAGCGT 
GCCTACAGCA GCCATGGGGA GACCATCACC AGCCTGCCTG TCAGCATTCC ACTCAGCACA 
GTACAGCCCA ACAAGCTGCC TGTCAGCATC CCGCTAGCCA GCGTGGTGCT GCCCAGCCGT 
GCCGAGAGGG CGAGGAGCAC TCCCAGCCCT GTGCCCCAGC CTCGAGACTC CTCATCCACA 
CTTGAGAAGC AGATTGGTGC TTCCACCCAT GGTGCAGGGG GTGCTGCGGC AGGAAGCAGG 
AGCCTCACTG TGGCGCCCAC AGGTTTCTAT GCTGGTTCGG TGGCCATCAG TGGGGCTCTG 
GCCAGCAGCC CAGCACCTCT GGCCTCTGGA ATGGAATCTG CTGTTTTTGA GGAGTCCTCT 
GGCCCCAGCA GCCTCTTTGG CACCATGGGG TCTCGCAGCA CACCGCCACA ACATCCACCT 
CTCCTGCCGC AGTCTCGCAA CTCGGGCCCT GCCTCTCCTG CCCACCAGCT CGCAGCCAGT 
CCCCGCCTGA GTGTGACCAC CCAGGGCTCA CTGCCAGACA CCGGCAAAGG GGAGCTGCCT 
GCTGATCCTG CCTTCTCAGA CCCAGAGAGT GAAGCTAAGA GGAGGATTGT GTTCAGCATT 
TCAGCTGGTG CCAGCTCCAG GCAGTCGCCT TCCACCAGGC ACAGCCCCTT GACCTCTGGC 
ACCCGTGGGG ATTGTGTTCA GAGCCATGGG CAGGACAGTC GTAAGCGTAG CAGAAGGAAG 
CGTGCATCAG CTGGAACGCC TAGCCTCACC ACGGGTGTGT CCCCCAAGCG CCGAGCTCTG 
CCAACCGTCG CTGGCCTCTT TACACAGTCT TCGGGGTCGC CTCTCAATCT CACCTCCATG 
GTCAGCAACA TCAACCAGCC CCTGGAGATC ACAGCCATCT CATCCCCGGA GAGCTCACTG 
AAGAGCTCCC CCACACCCTA CCAGGACCAT GACCAGCCTC CAGTGCTCAG GAAGGAGCGG 
CCCCTGGGCC CAACTAATGG GGCCCACTAC TCTCCGCTGA CGTCAGATGA GGAGCCAGGC 
TCGGAGGACG AGCCCAGCAG TGCCCGAATT GAGAGAAAAA TTGCAACAAT CTCTTTAGAA 
AGCAAATCTC CCCCGAAGAC ACTGGAAAAT GGTGGTGGCT TAGTGGGAAG GAAGCCGGTC 
CCCTCAGGCG AGCCTGTCAA CAGCAGCAAA TGGAAGTCCA CCTTCTCACC CATCTCCGAC 
CTCGGCTTGG CCAAGGCCAT GGACAGTCCG CTACAGGCCA GCTCTGCACT GAGCCACAGC 
CCCCTCTTCT CTTTCCGGCC GTCCTTGGAG GAGCCTGCTG CTGAGGCCAA GCCCTCCACC 
CACCCAAGGA AAAGTTTTGC GGGCTCTCTG GCTGCAGCTG AGGGGCCAAG CCCTGGCACC 
AACCCTCCCA ACAGCCTGGC CTTCAGTGGG GGCCTTGCTG CAGACCTCGG TTTACATAGC 
TTCAATGACG GTGCTTCCCT CTCCCACAAG GGCCCGGAGG TGGCGGGCCT GAGCGCCTCC 
CTGAGCTTCC CATCCCAGAG GGGCAAGGAC AGTACCACAG AGGCCAACCC CTTCCTCAGC 
AGGCGGCAGC CGGAGGGCCT GGGTGGCCTG AAGGGTGAGG GCAATGCAAG CAAGGAGTCA 
GGAGAGAGCC TGCCCCTGTG TGGGCCCTCA GACAAGGTCT CACTGCCACA CGGCAGCAGG 
GCCAGCAAAG GCCGTGACCG CGAGCTGGAC TTCAAGGGCG GCCACAACCT CTTCATCTCT 
GCTGCAGCCG TGCCTCCAGG TGGCCTCCTT GGTGGCCCTG GTCTTGTAAC TGTGGCTTCC 
TCTGCGGGCA GTGCGACACC CTCTGCCCAG GCTCCCCGGC CTTTCCTGAG CACCTTTGCC 
CCTGGGCCCC AGTTTACTCT GGGCCCCATG TCCCTGCAGG CCAACCTGGG CTCTGTGGCC 
GGCTCCTCTG TGCTGCAGTC CTTGTTCAGC ACTGTGCCAG CTGCTGCAGG CCTGGTGCAT 
GTGTCATCCA CTGCGACCCG ACTGACCAAC TCACACACCA TGGGCAGCTT CTCCTCTGGG 
GTGGCCGGCG GAACCGTTGG AGGTAATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dot1l ( XM_006240961.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006241023.1 Rattus norvegicus DOT1 like histone lysine methyltransferase (Dot1l), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa29887
Clone ID Related Accession (Same CDS sequence)	XM_006240961.3
Accession Version	XM_006240961.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4623bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006240961.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCGAGA AGCTGGAGCT GAGGCTCAAG TCGCCTGTGG GCGCGGAGCC CGCCGTCTAC 
CCGTGGCCGC TGCCGGTCTA CGACAAGCAC CATGATGCTG CTCATGAGAT TATCGAGACT 
ATCCGATGGG TCTGCGAGGA AATCCCAGAT CTCAAGCTGG CCATGGAGAA CTATGTCCTG 
ATCGACTACG ACACCAAAAG TTTTGAAAGC ATGCAGAGGC TGTGTGACAA ATATAACCGG 
GCCATTGACA GCATCCACCA GCTGTGGAAG GGCACTACAC AGCCCATGAA GCTCAATACT 
CGGCCGTCCA ATGGGCTCCT GCGGCACATC CTGCAGCAGG TGTACAACCA CTCTGTGACC 
GACCCAGAGA AGCTCAACAA CTACGAGCCC TTCTCCCCCG AGGTGTACGG GGAGACCTCC 
TTTGACCTGG TGGCCCAGAT GATCGATGAG ATCAAGATGA CCGAGGATGA CCTGTTTGTA 
GACCTGGGCA GTGGTGTGGG GCAGGTTGTC CTTCAGGTTG CGGCGGCCAC CAACTGCAAA 
CATCACTACG GAGTGGAGAA AGCGGACATC CCAGCCAAGT ACGCGGAGAC CATGGATCGA 
GAGTTCAGGA AGTGGATGAA ATGGTATGGA AAAAAGCATG CAGAATACAC ACTGGAGCGA 
GGTGACTTCC TCTCAGAGGA GTGGAGGGAA CGGATCGCCA ACACGAGTGT TATATTTGTG 
AATAACTTTG CCTTTGGTCC TGAGGTGGAT CACCAGCTGA AGGAACGATT CGCAAACATG 
AAGGAAGGCG GCAGAATCGT ATCCTCAAAG CCCTTTGCCC CTCTGAACTT CAGGATCAAC 
AGCAGGAACT TGAGTGACAT TGGCACCATC ATGCGTGTGG TGGAGCTGTC GCCCCTGAAG 
GGCTCTGTGT CATGGACTGG CAAGCCTGTC TCCTACTACC TGCACACCAT TGACCGCACC 
ATACTTGAAA ACTATTTTTC TAGTCTGAAA AATCCAAAAC TCAGGGAGGA GCAGGAGGCA 
GCTAGGCGCA GGCAGCAGCG AGAGAACAAG AGCAACGCGA CCACACCCAC CAAAGTCCCT 
GAGAGCAAGG CAGCTGCCAC CGAGGCCCCT GCGGATTCTG GTGCTGAGGA AGAAAAATCA 
GGTGTGGCCA CCGTCAAAAA GCAATCTCCC TCCAAAGCCC GGAAGAAGAA ACTGAACAAG 
AAAGGGAGAA AAATGGCTGG CCGGAAGCGT GGGCGACCCA AGAAAATGAG TGCTGCCAGT 
GCCGATCGCA AGTCCAAGAA GAGCCAAAGC ACACTGGATC TCCTGCACTC TCCGCCCCCA 
GCCCCACCCT CAGCCTCACC CCAGGATGCA TACAGGGCCC CCCACAGCCC GTTCTACCAG 
CTACCTCCGA GCACGCCGCT GCACTCGCCC GACCCACTGC TAGTGGCTCC CACCCCACCC 
GCGCTGCAGA AGCTGTTAGA GTCCTTCAAG ATCCAGTACC TGCAGTTCCT GGCCTACACG 
AAGACCCCGC AGTACAAGGC CAACCTGCAG CAGCTTCTGG ACCAGGAGAA GGAGAAGAAC 
ACACAACTGC TGGGTACAGC CCAGCAGCTC TTCAGCCATT GCCAGGCACA AAAGGAAGAG 
ATCCGCAGGC TGTTCCAGCA GAAGCTGGAT GAGTTGGGCG TGAAGGCACT GACCTACAAT 
GACCTGATTC AGGCCCAGAA GGAAATCTCT GCCCACAACC AGCAGCTGCG GGAGCAGTCG 
GAACAGCTGG AGAAGGACAA CAGCGAGCTT CGGAGCCAGA GCCTGCGGCT GCTCAGGGCC 
CGGTGCGAAG AGCTGAGGCT TGACTGGTCC ACCTTGTCCC TGGAGAACCT GCGGAAAGAG 
AAGCAGGCCC TGCGGAGCCA GATCTCAGAG AAGCAGCGGC ACTGCCTAGA GCTGCAGATC 
AGCATCGTGG AGCTGGAGAA GACCCAGCGC CAGCAGGAGC TCCTGCAGTT GAAGTCCTGT 
GTGCCACCAG ATGACGCTCT GTCCCTGCAC CTGCGTGGCA AGGGTGCCCT GGGCCGCGAG 
CTGGAGTCTG ACGCTGGGCG CTTGCGCCTT GAGCTGGACT GTGCCAAGCT CTCCCTCCCA 
CACCTCAGCA GCATGAGCCC TGAGCTGTCC ATGAATGGCC ATGCCGCCAG CTATGAGCTC 
TGCGGTGCAG CTAGTCGGCC CTCGTCCAAG CAGAACACCC CCCAGTATCT GGCCTCCCCC 
TTGGACCAGG AGGTCGTGCC CTGCACCCCT AGCCACAGTG GCCGGCCTCG GCTGGAGAAG 
CTGTCTGGCC TGGCTTTGCC TGACTACACC CGGTTGTCAC CGGCCAAGAT TGTGTTGAGG 
CGGCACCTGA GCCAGGACCA CACCGGGGCC AGCAAAGCAG CTACTAGTGA GCCACACCCT 
CGGCCAGAGC ATGCCAAGGA GAACAGCCTT CCCTACCAGA GCCCTGGCTT GTCGAACAGC 
ATGAAGCTCA GCCCCCAGGA TCCACCGCTG GCCTCCCCGG CAACCTCACC CCTCACTTCC 
GAGAGGGGTA GTGAGAAGGG TGTAAAGGAG CGTGCCTACA GCAGCCATGG GGAGACCATC 
ACCAGCCTGC CTGTCAGCAT TCCACTCAGC ACAGTACAGC CCAACAAGCT GCCTGTCAGC 
ATCCCGCTAG CCAGCGTGGT GCTGCCCAGC CGTGCCGAGA GGGCGAGGAG CACTCCCAGC 
CCTGTGCCCC AGCCTCGAGA CTCCTCATCC ACACTTGAGA AGCAGATTGG TGCTTCCACC 
CATGGTGCAG GGGGTGCTGC GGCAGGAAGC AGGAGCCTCA CTGTGGCGCC CACAGGTTTC 
TATGCTGGTT CGGTGGCCAT CAGTGGGGCT CTGGCCAGCA GCCCAGCACC TCTGGCCTCT 
GGAATGGAAT CTGCTGTTTT TGAGGAGTCC TCTGGCCCCA GCAGCCTCTT TGGCACCATG 
GGGTCTCGCA GCACACCGCC ACAACATCCA CCTCTCCTGC CGCAGTCTCG CAACTCGGGC 
CCTGCCTCTC CTGCCCACCA GCTCGCAGCC AGTCCCCGCC TGAGTGTGAC CACCCAGGGC 
TCACTGCCAG ACACCGGCAA AGGGGAGCTG CCTGCTGATC CTGCCTTCTC AGACCCAGAG 
AGTGAAGCTA AGAGGAGGAT TGTGTTCAGC ATTTCAGCTG GTGCCAGCTC CAGGCAGTCG 
CCTTCCACCA GGCACAGCCC CTTGACCTCT GGCACCCGTG GGGATTGTGT TCAGAGCCAT 
GGGCAGGACA GTCGTAAGCG TAGCAGAAGG AAGCGTGCAT CAGCTGGAAC GCCTAGCCTC 
ACCACGGGTG TGTCCCCCAA GCGCCGAGCT CTGCCAACCG TCGCTGGCCT CTTTACACAG 
TCTTCGGGGT CGCCTCTCAA TCTCACCTCC ATGGTCAGCA ACATCAACCA GCCCCTGGAG 
ATCACAGCCA TCTCATCCCC GGAGAGCTCA CTGAAGAGCT CCCCCACACC CTACCAGGAC 
CATGACCAGC CTCCAGTGCT CAGGAAGGAG CGGCCCCTGG GCCCAACTAA TGGGGCCCAC 
TACTCTCCGC TGACGTCAGA TGAGGAGCCA GGCTCGGAGG ACGAGCCCAG CAGTGCCCGA 
ATTGAGAGAA AAATTGCAAC AATCTCTTTA GAAAGCAAAT CTCCCCCGAA GACACTGGAA 
AATGGTGGTG GCTTAGTGGG AAGGAAGCCG GTCCCCTCAG GCGAGCCTGT CAACAGCAGC 
AAATGGAAGT CCACCTTCTC ACCCATCTCC GACCTCGGCT TGGCCAAGGC CATGGACAGT 
CCGCTACAGG CCAGCTCTGC ACTGAGCCAC AGCCCCCTCT TCTCTTTCCG GCCGTCCTTG 
GAGGAGCCTG CTGCTGAGGC CAAGCCCTCC ACCCACCCAA GGAAAAGTTT TGCGGGCTCT 
CTGGCTGCAG CTGAGGGGCC AAGCCCTGGC ACCAACCCTC CCAACAGCCT GGCCTTCAGT 
GGGGGCCTTG CTGCAGACCT CGGTTTACAT AGCTTCAATG ACGGTGCTTC CCTCTCCCAC 
AAGGGCCCGG AGGTGGCGGG CCTGAGCGCC TCCCTGAGCT TCCCATCCCA GAGGGGCAAG 
GACAGTACCA CAGAGGCCAA CCCCTTCCTC AGCAGGCGGC AGCCGGAGGG CCTGGGTGGC 
CTGAAGGGTG AGGGCAATGC AAGCAAGGAG TCAGGAGAGA GCCTGCCCCT GTGTGGGCCC 
TCAGACAAGG TCTCACTGCC ACACGGCAGC AGGGCCAGCA AAGGCCGTGA CCGCGAGCTG 
GACTTCAAGG GCGGCCACAA CCTCTTCATC TCTGCTGCAG CCGTGCCTCC AGGTGGCCTC 
CTTGGTGGCC CTGGTCTTGT AACTGTGGCT TCCTCTGCGG GCAGTGCGAC ACCCTCTGCC 
CAGGCTCCCC GGCCTTTCCT GAGCACCTTT GCCCCTGGGC CCCAGTTTAC TCTGGGCCCC 
ATGTCCCTGC AGGCCAACCT GGGCTCTGTG GCCGGCTCCT CTGTGCTGCA GTCCTTGTTC 
AGCACTGTGC CAGCTGCTGC AGGCCTGGTG CATGTGTCAT CCACTGCGAC CCGACTGACC 
AACTCACACA CCATGGGCAG CTTCTCCTCT GGGGTGGCCG GCGGAACCGT TGGAGGTAAT 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006241023.1
CDS	235..4857
Translation	MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNATTPTKVPESKAAATEAPADSGAEEEKSGVATVKKQSPSKARKKKLNKKGRKMAGRKRGRPKKMSAASADRKSKKSQSTLDLLHSPPPAPPSASPQDAYRAPHSPFYQLPPSTPLHSPDPLLVAPTPPALQKLLESFKIQYLQFLAYTKTPQYKANLQQLLDQEKEKNTQLLGTAQQLFSHCQAQKEEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEKDNSELRSQSLRLLRARCEELRLDWSTLSLENLRKEKQALRSQISEKQRHCLELQISIVELEKTQRQQELLQLKSCVPPDDALSLHLRGKGALGRELESDAGRLRLELDCAKLSLPHLSSMSPELSMNGHAASYELCGAASRPSSKQNTPQYLASPLDQEVVPCTPSHSGRPRLEKLSGLALPDYTRLSPAKIVLRRHLSQDHTGASKAATSEPHPRPEHAKENSLPYQSPGLSNSMKLSPQDPPLASPATSPLTSERGSEKGVKERAYSSHGETITSLPVSIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPSPVPQPRDSSSTLEKQIGASTHGAGGAAAGSRSLTVAPTGFYAGSVAISGALASSPAPLASGMESAVFEESSGPSSLFGTMGSRSTPPQHPPLLPQSRNSGPASPAHQLAASPRLSVTTQGSLPDTGKGELPADPAFSDPESEAKRRIVFSISAGASSRQSPSTRHSPLTSGTRGDCVQSHGQDSRKRSRRKRASAGTPSLTTGVSPKRRALPTVAGLFTQSSGSPLNLTSMVSNINQPLEITAISSPESSLKSSPTPYQDHDQPPVLRKERPLGPTNGAHYSPLTSDEEPGSEDEPSSARIERKIATISLESKSPPKTLENGGGLVGRKPVPSGEPVNSSKWKSTFSPISDLGLAKAMDSPLQASSALSHSPLFSFRPSLEEPAAEAKPSTHPRKSFAGSLAAAEGPSPGTNPPNSLAFSGGLAADLGLHSFNDGASLSHKGPEVAGLSASLSFPSQRGKDSTTEANPFLSRRQPEGLGGLKGEGNASKESGESLPLCGPSDKVSLPHGSRASKGRDRELDFKGGHNLFISAAAVPPGGLLGGPGLVTVASSAGSATPSAQAPRPFLSTFAPGPQFTLGPMSLQANLGSVAGSSVLQSLFSTVPAAAGLVHVSSTATRLTNSHTMGSFSSGVAGGTVGGN

Target ORF information:

RefSeq Version	XM_006240961.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus DOT1 like histone lysine methyltransferase (Dot1l), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006240961.3

ORF Insert Sequence:

ATGGGCGAGA AGCTGGAGCT GAGGCTCAAG TCGCCTGTGG GCGCGGAGCC CGCCGTCTAC 
CCGTGGCCGC TGCCGGTCTA CGACAAGCAC CATGATGCTG CTCATGAGAT TATCGAGACT 
ATCCGATGGG TCTGCGAGGA AATCCCAGAT CTCAAGCTGG CCATGGAGAA CTATGTCCTG 
ATCGACTACG ACACCAAAAG TTTTGAAAGC ATGCAGAGGC TGTGTGACAA ATATAACCGG 
GCCATTGACA GCATCCACCA GCTGTGGAAG GGCACTACAC AGCCCATGAA GCTCAATACT 
CGGCCGTCCA ATGGGCTCCT GCGGCACATC CTGCAGCAGG TGTACAACCA CTCTGTGACC 
GACCCAGAGA AGCTCAACAA CTACGAGCCC TTCTCCCCCG AGGTGTACGG GGAGACCTCC 
TTTGACCTGG TGGCCCAGAT GATCGATGAG ATCAAGATGA CCGAGGATGA CCTGTTTGTA 
GACCTGGGCA GTGGTGTGGG GCAGGTTGTC CTTCAGGTTG CGGCGGCCAC CAACTGCAAA 
CATCACTACG GAGTGGAGAA AGCGGACATC CCAGCCAAGT ACGCGGAGAC CATGGATCGA 
GAGTTCAGGA AGTGGATGAA ATGGTATGGA AAAAAGCATG CAGAATACAC ACTGGAGCGA 
GGTGACTTCC TCTCAGAGGA GTGGAGGGAA CGGATCGCCA ACACGAGTGT TATATTTGTG 
AATAACTTTG CCTTTGGTCC TGAGGTGGAT CACCAGCTGA AGGAACGATT CGCAAACATG 
AAGGAAGGCG GCAGAATCGT ATCCTCAAAG CCCTTTGCCC CTCTGAACTT CAGGATCAAC 
AGCAGGAACT TGAGTGACAT TGGCACCATC ATGCGTGTGG TGGAGCTGTC GCCCCTGAAG 
GGCTCTGTGT CATGGACTGG CAAGCCTGTC TCCTACTACC TGCACACCAT TGACCGCACC 
ATACTTGAAA ACTATTTTTC TAGTCTGAAA AATCCAAAAC TCAGGGAGGA GCAGGAGGCA 
GCTAGGCGCA GGCAGCAGCG AGAGAACAAG AGCAACGCGA CCACACCCAC CAAAGTCCCT 
GAGAGCAAGG CAGCTGCCAC CGAGGCCCCT GCGGATTCTG GTGCTGAGGA AGAAAAATCA 
GGTGTGGCCA CCGTCAAAAA GCAATCTCCC TCCAAAGCCC GGAAGAAGAA ACTGAACAAG 
AAAGGGAGAA AAATGGCTGG CCGGAAGCGT GGGCGACCCA AGAAAATGAG TGCTGCCAGT 
GCCGATCGCA AGTCCAAGAA GAGCCAAAGC ACACTGGATC TCCTGCACTC TCCGCCCCCA 
GCCCCACCCT CAGCCTCACC CCAGGATGCA TACAGGGCCC CCCACAGCCC GTTCTACCAG 
CTACCTCCGA GCACGCCGCT GCACTCGCCC GACCCACTGC TAGTGGCTCC CACCCCACCC 
GCGCTGCAGA AGCTGTTAGA GTCCTTCAAG ATCCAGTACC TGCAGTTCCT GGCCTACACG 
AAGACCCCGC AGTACAAGGC CAACCTGCAG CAGCTTCTGG ACCAGGAGAA GGAGAAGAAC 
ACACAACTGC TGGGTACAGC CCAGCAGCTC TTCAGCCATT GCCAGGCACA AAAGGAAGAG 
ATCCGCAGGC TGTTCCAGCA GAAGCTGGAT GAGTTGGGCG TGAAGGCACT GACCTACAAT 
GACCTGATTC AGGCCCAGAA GGAAATCTCT GCCCACAACC AGCAGCTGCG GGAGCAGTCG 
GAACAGCTGG AGAAGGACAA CAGCGAGCTT CGGAGCCAGA GCCTGCGGCT GCTCAGGGCC 
CGGTGCGAAG AGCTGAGGCT TGACTGGTCC ACCTTGTCCC TGGAGAACCT GCGGAAAGAG 
AAGCAGGCCC TGCGGAGCCA GATCTCAGAG AAGCAGCGGC ACTGCCTAGA GCTGCAGATC 
AGCATCGTGG AGCTGGAGAA GACCCAGCGC CAGCAGGAGC TCCTGCAGTT GAAGTCCTGT 
GTGCCACCAG ATGACGCTCT GTCCCTGCAC CTGCGTGGCA AGGGTGCCCT GGGCCGCGAG 
CTGGAGTCTG ACGCTGGGCG CTTGCGCCTT GAGCTGGACT GTGCCAAGCT CTCCCTCCCA 
CACCTCAGCA GCATGAGCCC TGAGCTGTCC ATGAATGGCC ATGCCGCCAG CTATGAGCTC 
TGCGGTGCAG CTAGTCGGCC CTCGTCCAAG CAGAACACCC CCCAGTATCT GGCCTCCCCC 
TTGGACCAGG AGGTCGTGCC CTGCACCCCT AGCCACAGTG GCCGGCCTCG GCTGGAGAAG 
CTGTCTGGCC TGGCTTTGCC TGACTACACC CGGTTGTCAC CGGCCAAGAT TGTGTTGAGG 
CGGCACCTGA GCCAGGACCA CACCGGGGCC AGCAAAGCAG CTACTAGTGA GCCACACCCT 
CGGCCAGAGC ATGCCAAGGA GAACAGCCTT CCCTACCAGA GCCCTGGCTT GTCGAACAGC 
ATGAAGCTCA GCCCCCAGGA TCCACCGCTG GCCTCCCCGG CAACCTCACC CCTCACTTCC 
GAGAGGGGTA GTGAGAAGGG TGTAAAGGAG CGTGCCTACA GCAGCCATGG GGAGACCATC 
ACCAGCCTGC CTGTCAGCAT TCCACTCAGC ACAGTACAGC CCAACAAGCT GCCTGTCAGC 
ATCCCGCTAG CCAGCGTGGT GCTGCCCAGC CGTGCCGAGA GGGCGAGGAG CACTCCCAGC 
CCTGTGCCCC AGCCTCGAGA CTCCTCATCC ACACTTGAGA AGCAGATTGG TGCTTCCACC 
CATGGTGCAG GGGGTGCTGC GGCAGGAAGC AGGAGCCTCA CTGTGGCGCC CACAGGTTTC 
TATGCTGGTT CGGTGGCCAT CAGTGGGGCT CTGGCCAGCA GCCCAGCACC TCTGGCCTCT 
GGAATGGAAT CTGCTGTTTT TGAGGAGTCC TCTGGCCCCA GCAGCCTCTT TGGCACCATG 
GGGTCTCGCA GCACACCGCC ACAACATCCA CCTCTCCTGC CGCAGTCTCG CAACTCGGGC 
CCTGCCTCTC CTGCCCACCA GCTCGCAGCC AGTCCCCGCC TGAGTGTGAC CACCCAGGGC 
TCACTGCCAG ACACCGGCAA AGGGGAGCTG CCTGCTGATC CTGCCTTCTC AGACCCAGAG 
AGTGAAGCTA AGAGGAGGAT TGTGTTCAGC ATTTCAGCTG GTGCCAGCTC CAGGCAGTCG 
CCTTCCACCA GGCACAGCCC CTTGACCTCT GGCACCCGTG GGGATTGTGT TCAGAGCCAT 
GGGCAGGACA GTCGTAAGCG TAGCAGAAGG AAGCGTGCAT CAGCTGGAAC GCCTAGCCTC 
ACCACGGGTG TGTCCCCCAA GCGCCGAGCT CTGCCAACCG TCGCTGGCCT CTTTACACAG 
TCTTCGGGGT CGCCTCTCAA TCTCACCTCC ATGGTCAGCA ACATCAACCA GCCCCTGGAG 
ATCACAGCCA TCTCATCCCC GGAGAGCTCA CTGAAGAGCT CCCCCACACC CTACCAGGAC 
CATGACCAGC CTCCAGTGCT CAGGAAGGAG CGGCCCCTGG GCCCAACTAA TGGGGCCCAC 
TACTCTCCGC TGACGTCAGA TGAGGAGCCA GGCTCGGAGG ACGAGCCCAG CAGTGCCCGA 
ATTGAGAGAA AAATTGCAAC AATCTCTTTA GAAAGCAAAT CTCCCCCGAA GACACTGGAA 
AATGGTGGTG GCTTAGTGGG AAGGAAGCCG GTCCCCTCAG GCGAGCCTGT CAACAGCAGC 
AAATGGAAGT CCACCTTCTC ACCCATCTCC GACCTCGGCT TGGCCAAGGC CATGGACAGT 
CCGCTACAGG CCAGCTCTGC ACTGAGCCAC AGCCCCCTCT TCTCTTTCCG GCCGTCCTTG 
GAGGAGCCTG CTGCTGAGGC CAAGCCCTCC ACCCACCCAA GGAAAAGTTT TGCGGGCTCT 
CTGGCTGCAG CTGAGGGGCC AAGCCCTGGC ACCAACCCTC CCAACAGCCT GGCCTTCAGT 
GGGGGCCTTG CTGCAGACCT CGGTTTACAT AGCTTCAATG ACGGTGCTTC CCTCTCCCAC 
AAGGGCCCGG AGGTGGCGGG CCTGAGCGCC TCCCTGAGCT TCCCATCCCA GAGGGGCAAG 
GACAGTACCA CAGAGGCCAA CCCCTTCCTC AGCAGGCGGC AGCCGGAGGG CCTGGGTGGC 
CTGAAGGGTG AGGGCAATGC AAGCAAGGAG TCAGGAGAGA GCCTGCCCCT GTGTGGGCCC 
TCAGACAAGG TCTCACTGCC ACACGGCAGC AGGGCCAGCA AAGGCCGTGA CCGCGAGCTG 
GACTTCAAGG GCGGCCACAA CCTCTTCATC TCTGCTGCAG CCGTGCCTCC AGGTGGCCTC 
CTTGGTGGCC CTGGTCTTGT AACTGTGGCT TCCTCTGCGG GCAGTGCGAC ACCCTCTGCC 
CAGGCTCCCC GGCCTTTCCT GAGCACCTTT GCCCCTGGGC CCCAGTTTAC TCTGGGCCCC 
ATGTCCCTGC AGGCCAACCT GGGCTCTGTG GCCGGCTCCT CTGTGCTGCA GTCCTTGTTC 
AGCACTGTGC CAGCTGCTGC AGGCCTGGTG CATGTGTCAT CCACTGCGAC CCGACTGACC 
AACTCACACA CCATGGGCAG CTTCTCCTCT GGGGTGGCCG GCGGAACCGT TGGAGGTAAT 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dot1l ( XM_006240960.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006241022.1 Rattus norvegicus DOT1 like histone lysine methyltransferase (Dot1l), transcript variant X2, mRNA.

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CloneID	ORa29886
Clone ID Related Accession (Same CDS sequence)	XM_006240960.3 , XM_006240959.3
Accession Version	XM_006240960.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5211bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006240960.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCGAGA AGCTGGAGCT GAGGCTCAAG TCGCCTGTGG GCGCGGAGCC CGCCGTCTAC 
CCGTGGCCGC TGCCGGTCTA CGACAAGCAC CATGATGCTG CTCATGAGAT TATCGAGACT 
ATCCGATGGG TCTGCGAGGA AATCCCAGAT CTCAAGCTGG CCATGGAGAA CTATGTCCTG 
ATCGACTACG ACACCAAAAG TTTTGAAAGC ATGCAGAGGC TGTGTGACAA ATATAACCGG 
GCCATTGACA GCATCCACCA GCTGTGGAAG GGCACTACAC AGCCCATGAA GCTCAATACT 
CGGCCGTCCA ATGGGCTCCT GCGGCACATC CTGCAGCAGG TGTACAACCA CTCTGTGACC 
GACCCAGAGA AGCTCAACAA CTACGAGCCC TTCTCCCCCG AGGTGTACGG GGAGACCTCC 
TTTGACCTGG TGGCCCAGAT GATCGATGAG ATCAAGATGA CCGAGGATGA CCTGTTTGTA 
GACCTGGGCA GTGGTGTGGG GCAGGTTGTC CTTCAGGTTG CGGCGGCCAC CAACTGCAAA 
CATCACTACG GAGTGGAGAA AGCGGACATC CCAGCCAAGT ACGCGGAGAC CATGGATCGA 
GAGTTCAGGA AGTGGATGAA ATGGTATGGA AAAAAGCATG CAGAATACAC ACTGGAGCGA 
GGTGACTTCC TCTCAGAGGA GTGGAGGGAA CGGATCGCCA ACACGAGTGT TATATTTGTG 
AATAACTTTG CCTTTGGTCC TGAGGTGGAT CACCAGCTGA AGGAACGATT CGCAAACATG 
AAGGAAGGCG GCAGAATCGT ATCCTCAAAG CCCTTTGCCC CTCTGAACTT CAGGATCAAC 
AGCAGGAACT TGAGTGACAT TGGCACCATC ATGCGTGTGG TGGAGCTGTC GCCCCTGAAG 
GGCTCTGTGT CATGGACTGG CAAGCCTGTC TCCTACTACC TGCACACCAT TGACCGCACC 
ATACTTGAAA ACTATTTTTC TAGTCTGAAA AATCCAAAAC TCAGGGAGGA GCAGGAGGCA 
GCTAGGCGCA GGCAGCAGCG AGAGAACAAG AGCAACGCGA CCACACCCAC CAAAGTCCCT 
GAGAGCAAGG CAGCTGCCAC CGAGGCCCCT GCGGATTCTG GTGCTGAGGA AGAAAAATCA 
GGTGTGGCCA CCGTCAAAAA GCAATCTCCC TCCAAAGCCC GGAAGAAGAA ACTGAACAAG 
AAAGGGAGAA AAATGGCTGG CCGGAAGCGT GGGCGACCCA AGAAAATGAG TGCTGCCAGT 
GCCGATCGCA AGTCCAAGAA GAGCCAAAGC ACACTGGATC TCCTGCACTC TCCGCCCCCA 
GCCCCACCCT CAGCCTCACC CCAGGATGCA TACAGGGCCC CCCACAGCCC GTTCTACCAG 
CTACCTCCGA GCACGCCGCT GCACTCGCCC GACCCACTGC TAGTGGCTCC CACCCCACCC 
GCGCTGCAGA AGCTGTTAGA GTCCTTCAAG ATCCAGTACC TGCAGTTCCT GGCCTACACG 
AAGACCCCGC AGTACAAGGC CAACCTGCAG CAGCTTCTGG ACCAGGAGAA GGAGAAGAAC 
ACACAACTGC TGGGTACAGC CCAGCAGCTC TTCAGCCATT GCCAGGCACA AAAGGAAGAG 
ATCCGCAGGC TGTTCCAGCA GAAGCTGGAT GAGTTGGGCG TGAAGGCACT GACCTACAAT 
GACCTGATTC AGGCCCAGAA GGAAATCTCT GCCCACAACC AGCAGCTGCG GGAGCAGTCG 
GAACAGCTGG AGAAGGACAA CAGCGAGCTT CGGAGCCAGA GCCTGCGGCT GCTCAGGGCC 
CGGTGCGAAG AGCTGAGGCT TGACTGGTCC ACCTTGTCCC TGGAGAACCT GCGGAAAGAG 
AAGCAGGCCC TGCGGAGCCA GATCTCAGAG AAGCAGCGGC ACTGCCTAGA GCTGCAGATC 
AGCATCGTGG AGCTGGAGAA GACCCAGCGC CAGCAGGAGC TCCTGCAGTT GAAGTCCTGT 
GTGCCACCAG ATGACGCTCT GTCCCTGCAC CTGCGTGGCA AGGGTGCCCT GGGCCGCGAG 
CTGGAGTCTG ACGCTGGGCG CTTGCGCCTT GAGCTGGACT GTGCCAAGCT CTCCCTCCCA 
CACCTCAGCA GCATGAGCCC TGAGCTGTCC ATGAATGGCC ATGCCGCCAG CTATGAGCTC 
TGCGGTGCAG CTAGTCGGCC CTCGTCCAAG CAGAACACCC CCCAGTATCT GGCCTCCCCC 
TTGGACCAGG AGGTCGTGCC CTGCACCCCT AGCCACAGTG GCCGGCCTCG GCTGGAGAAG 
CTGTCTGGCC TGGCTTTGCC TGACTACACC CGGTTGTCAC CGGCCAAGAT TGTGTTGAGG 
CGGCACCTGA GCCAGGACCA CACCGGGGCC AGCAAAGCAG CTACTAGTGA GCCACACCCT 
CGGCCAGAGC ATGCCAAGGA GAACAGCCTT CCCTACCAGA GCCCTGGCTT GTCGAACAGC 
ATGAAGCTCA GCCCCCAGGA TCCACCGCTG GCCTCCCCGG CAACCTCACC CCTCACTTCC 
GAGAGGGGTA GTGAGAAGGG TGTAAAGGAG CGTGCCTACA GCAGCCATGG GGAGACCATC 
ACCAGCCTGC CTGTCAGCAT TCCACTCAGC ACAGTACAGC CCAACAAGCT GCCTGTCAGC 
ATCCCGCTAG CCAGCGTGGT GCTGCCCAGC CGTGCCGAGA GGGCGAGGAG CACTCCCAGC 
CCTGTGCCCC AGCCTCGAGA CTCCTCATCC ACACTTGAGA AGCAGATTGG TGCTTCCACC 
CATGGTGCAG GGGGTGCTGC GGCAGGAAGC AGGAGCCTCA CTGTGGCGCC CACAGGTTTC 
TATGCTGGTT CGGTGGCCAT CAGTGGGGCT CTGGCCAGCA GCCCAGCACC TCTGGCCTCT 
GGAATGGAAT CTGCTGTTTT TGAGGAGTCC TCTGGCCCCA GCAGCCTCTT TGGCACCATG 
GGGTCTCGCA GCACACCGCC ACAACATCCA CCTCTCCTGC CGCAGTCTCG CAACTCGGGC 
CCTGCCTCTC CTGCCCACCA GCTCGCAGCC AGTCCCCGCC TGAGTGTGAC CACCCAGGGC 
TCACTGCCAG ACACCGGCAA AGGGGAGCTG CCTGCTGATC CTGCCTTCTC AGACCCAGAG 
AGTGAAGCTA AGAGGAGGAT TGTGTTCAGC ATTTCAGCTG GTGCCAGCTC CAGGCAGTCG 
CCTTCCACCA GGCACAGCCC CTTGACCTCT GGCACCCGTG GGGATTGTGT TCAGAGCCAT 
GGGCAGGACA GTCGTAAGCG TAGCAGAAGG AAGCGTGCAT CAGCTGGAAC GCCTAGCCTC 
ACCACGGGTG TGTCCCCCAA GCGCCGAGCT CTGCCAACCG TCGCTGGCCT CTTTACACAG 
TCTTCGGGGT CGCCTCTCAA TCTCACCTCC ATGGTCAGCA ACATCAACCA GCCCCTGGAG 
ATCACAGCCA TCTCATCCCC GGAGAGCTCA CTGAAGAGCT CCCCCACACC CTACCAGGAC 
CATGACCAGC CTCCAGTGCT CAGGAAGGAG CGGCCCCTGG GCCCAACTAA TGGGGCCCAC 
TACTCTCCGC TGACGTCAGA TGAGGAGCCA GGCTCGGAGG ACGAGCCCAG CAGTGCCCGA 
ATTGAGAGAA AAATTGCAAC AATCTCTTTA GAAAGCAAAT CTCCCCCGAA GACACTGGAA 
AATGGTGGTG GCTTAGTGGG AAGGAAGCCG GTCCCCTCAG GCGAGCCTGT CAACAGCAGC 
AAATGGAAGT CCACCTTCTC ACCCATCTCC GACCTCGGCT TGGCCAAGGC CATGGACAGT 
CCGCTACAGG CCAGCTCTGC ACTGAGCCAC AGCCCCCTCT TCTCTTTCCG GCCGTCCTTG 
GAGGAGCCTG CTGCTGAGGC CAAGCCCTCC ACCCACCCAA GGAAAAGTTT TGCGGGCTCT 
CTGGCTGCAG CTGAGGGGCC AAGCCCTGGC ACCAACCCTC CCAACAGCCT GGCCTTCAGT 
GGGGGCCTTG CTGCAGACCT CGGTTTACAT AGCTTCAATG ACGGTGCTTC CCTCTCCCAC 
AAGGGCCCGG AGGTGGCGGG CCTGAGCGCC TCCCTGAGCT TCCCATCCCA GAGGGGCAAG 
GACAGTACCA CAGAGGCCAA CCCCTTCCTC AGCAGGCGGC AGCCGGAGGG CCTGGGTGGC 
CTGAAGGGTG AGGGCAATGC AAGCAAGGAG TCAGGAGAGA GCCTGCCCCT GTGTGGGCCC 
TCAGACAAGG TCTCACTGCC ACACGGCAGC AGGGCCAGCA AAGGCCGTGA CCGCGAGCTG 
GACTTCAAGG GCGGCCACAA CCTCTTCATC TCTGCTGCAG CCGTGCCTCC AGGTGGCCTC 
CTTGGTGGCC CTGGTCTTGT AACTGTGGCT TCCTCTGCGG GCAGTGCGAC ACCCTCTGCC 
CAGGCTCCCC GGCCTTTCCT GAGCACCTTT GCCCCTGGGC CCCAGTTTAC TCTGGGCCCC 
ATGTCCCTGC AGGCCAACCT GGGCTCTGTG GCCGGCTCCT CTGTGCTGCA GTCCTTGTTC 
AGCACTGTGC CAGCTGCTGC AGGCCTGGTG CATGTGTCAT CCACTGCGAC CCGACTGACC 
AACTCACACA CCATGGGCAG CTTCTCCTCT GGGGTGGCCG GCGGAACCGT TGGAGGTGTC 
TTTACCCACG CGGTGCCCTC CGCCTCTGCT CACCCGTTTG GAGCTGGTGT CGGCAGCGGG 
GCTGTGTGTA GCAGTGCCAC GCTGGGCCTG AGCCCGCTGC AGGCGGCGGC CAGCACCTCG 
GCTTCTTCCT TTCAGGCCGC GGCTTCTGTT GAGACTCGGC CGCCCCCTCC ACCTCCCCTA 
CTTCCTCCTC AGCATCTCGG CCGGCCTCCT GCAGGGCCAC CTGTCCTCCA TGCACCCCCT 
CCTCCTAACG TCGCCTTGCC TCCTCCGCCT GCGCTGCTGG CTTCTAACCC TGAGCCAGTG 
CTTCTGCAGA GCCTGGCCTC CCTCCCGGCT AACAACGCTT TCTTACCCCC CTCCTCTGCC 
TCCTCTCTGC AGCCTGCTAA TGCCTCTCTA TCTGTCAAGC TCGCCTCCCT CCCACACAAG 
GTCTCCCGCC CCTCCTTCAC GGTGCACCAC CAGCCCCTGC CCCGGCTGGC CCTGGCGCAG 
GCCGCGCCCG CCGCACCACA GGCCAGCACC TCGGGGCCAT CTGCTGTGTG GGTTTCCCTT 
GGCATGCCGC CTCCTTATGC CGCGCACCTT TCAGGGGTTA AGCCTCGATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006241022.1
CDS	235..5445
Translation	MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNATTPTKVPESKAAATEAPADSGAEEEKSGVATVKKQSPSKARKKKLNKKGRKMAGRKRGRPKKMSAASADRKSKKSQSTLDLLHSPPPAPPSASPQDAYRAPHSPFYQLPPSTPLHSPDPLLVAPTPPALQKLLESFKIQYLQFLAYTKTPQYKANLQQLLDQEKEKNTQLLGTAQQLFSHCQAQKEEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEKDNSELRSQSLRLLRARCEELRLDWSTLSLENLRKEKQALRSQISEKQRHCLELQISIVELEKTQRQQELLQLKSCVPPDDALSLHLRGKGALGRELESDAGRLRLELDCAKLSLPHLSSMSPELSMNGHAASYELCGAASRPSSKQNTPQYLASPLDQEVVPCTPSHSGRPRLEKLSGLALPDYTRLSPAKIVLRRHLSQDHTGASKAATSEPHPRPEHAKENSLPYQSPGLSNSMKLSPQDPPLASPATSPLTSERGSEKGVKERAYSSHGETITSLPVSIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPSPVPQPRDSSSTLEKQIGASTHGAGGAAAGSRSLTVAPTGFYAGSVAISGALASSPAPLASGMESAVFEESSGPSSLFGTMGSRSTPPQHPPLLPQSRNSGPASPAHQLAASPRLSVTTQGSLPDTGKGELPADPAFSDPESEAKRRIVFSISAGASSRQSPSTRHSPLTSGTRGDCVQSHGQDSRKRSRRKRASAGTPSLTTGVSPKRRALPTVAGLFTQSSGSPLNLTSMVSNINQPLEITAISSPESSLKSSPTPYQDHDQPPVLRKERPLGPTNGAHYSPLTSDEEPGSEDEPSSARIERKIATISLESKSPPKTLENGGGLVGRKPVPSGEPVNSSKWKSTFSPISDLGLAKAMDSPLQASSALSHSPLFSFRPSLEEPAAEAKPSTHPRKSFAGSLAAAEGPSPGTNPPNSLAFSGGLAADLGLHSFNDGASLSHKGPEVAGLSASLSFPSQRGKDSTTEANPFLSRRQPEGLGGLKGEGNASKESGESLPLCGPSDKVSLPHGSRASKGRDRELDFKGGHNLFISAAAVPPGGLLGGPGLVTVASSAGSATPSAQAPRPFLSTFAPGPQFTLGPMSLQANLGSVAGSSVLQSLFSTVPAAAGLVHVSSTATRLTNSHTMGSFSSGVAGGTVGGVFTHAVPSASAHPFGAGVGSGAVCSSATLGLSPLQAAASTSASSFQAAASVETRPPPPPPLLPPQHLGRPPAGPPVLHAPPPPNVALPPPPALLASNPEPVLLQSLASLPANNAFLPPSSASSLQPANASLSVKLASLPHKVSRPSFTVHHQPLPRLALAQAAPAAPQASTSGPSAVWVSLGMPPPYAAHLSGVKPR

Target ORF information:

RefSeq Version	XM_006240960.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus DOT1 like histone lysine methyltransferase (Dot1l), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006240960.3

ORF Insert Sequence:

ATGGGCGAGA AGCTGGAGCT GAGGCTCAAG TCGCCTGTGG GCGCGGAGCC CGCCGTCTAC 
CCGTGGCCGC TGCCGGTCTA CGACAAGCAC CATGATGCTG CTCATGAGAT TATCGAGACT 
ATCCGATGGG TCTGCGAGGA AATCCCAGAT CTCAAGCTGG CCATGGAGAA CTATGTCCTG 
ATCGACTACG ACACCAAAAG TTTTGAAAGC ATGCAGAGGC TGTGTGACAA ATATAACCGG 
GCCATTGACA GCATCCACCA GCTGTGGAAG GGCACTACAC AGCCCATGAA GCTCAATACT 
CGGCCGTCCA ATGGGCTCCT GCGGCACATC CTGCAGCAGG TGTACAACCA CTCTGTGACC 
GACCCAGAGA AGCTCAACAA CTACGAGCCC TTCTCCCCCG AGGTGTACGG GGAGACCTCC 
TTTGACCTGG TGGCCCAGAT GATCGATGAG ATCAAGATGA CCGAGGATGA CCTGTTTGTA 
GACCTGGGCA GTGGTGTGGG GCAGGTTGTC CTTCAGGTTG CGGCGGCCAC CAACTGCAAA 
CATCACTACG GAGTGGAGAA AGCGGACATC CCAGCCAAGT ACGCGGAGAC CATGGATCGA 
GAGTTCAGGA AGTGGATGAA ATGGTATGGA AAAAAGCATG CAGAATACAC ACTGGAGCGA 
GGTGACTTCC TCTCAGAGGA GTGGAGGGAA CGGATCGCCA ACACGAGTGT TATATTTGTG 
AATAACTTTG CCTTTGGTCC TGAGGTGGAT CACCAGCTGA AGGAACGATT CGCAAACATG 
AAGGAAGGCG GCAGAATCGT ATCCTCAAAG CCCTTTGCCC CTCTGAACTT CAGGATCAAC 
AGCAGGAACT TGAGTGACAT TGGCACCATC ATGCGTGTGG TGGAGCTGTC GCCCCTGAAG 
GGCTCTGTGT CATGGACTGG CAAGCCTGTC TCCTACTACC TGCACACCAT TGACCGCACC 
ATACTTGAAA ACTATTTTTC TAGTCTGAAA AATCCAAAAC TCAGGGAGGA GCAGGAGGCA 
GCTAGGCGCA GGCAGCAGCG AGAGAACAAG AGCAACGCGA CCACACCCAC CAAAGTCCCT 
GAGAGCAAGG CAGCTGCCAC CGAGGCCCCT GCGGATTCTG GTGCTGAGGA AGAAAAATCA 
GGTGTGGCCA CCGTCAAAAA GCAATCTCCC TCCAAAGCCC GGAAGAAGAA ACTGAACAAG 
AAAGGGAGAA AAATGGCTGG CCGGAAGCGT GGGCGACCCA AGAAAATGAG TGCTGCCAGT 
GCCGATCGCA AGTCCAAGAA GAGCCAAAGC ACACTGGATC TCCTGCACTC TCCGCCCCCA 
GCCCCACCCT CAGCCTCACC CCAGGATGCA TACAGGGCCC CCCACAGCCC GTTCTACCAG 
CTACCTCCGA GCACGCCGCT GCACTCGCCC GACCCACTGC TAGTGGCTCC CACCCCACCC 
GCGCTGCAGA AGCTGTTAGA GTCCTTCAAG ATCCAGTACC TGCAGTTCCT GGCCTACACG 
AAGACCCCGC AGTACAAGGC CAACCTGCAG CAGCTTCTGG ACCAGGAGAA GGAGAAGAAC 
ACACAACTGC TGGGTACAGC CCAGCAGCTC TTCAGCCATT GCCAGGCACA AAAGGAAGAG 
ATCCGCAGGC TGTTCCAGCA GAAGCTGGAT GAGTTGGGCG TGAAGGCACT GACCTACAAT 
GACCTGATTC AGGCCCAGAA GGAAATCTCT GCCCACAACC AGCAGCTGCG GGAGCAGTCG 
GAACAGCTGG AGAAGGACAA CAGCGAGCTT CGGAGCCAGA GCCTGCGGCT GCTCAGGGCC 
CGGTGCGAAG AGCTGAGGCT TGACTGGTCC ACCTTGTCCC TGGAGAACCT GCGGAAAGAG 
AAGCAGGCCC TGCGGAGCCA GATCTCAGAG AAGCAGCGGC ACTGCCTAGA GCTGCAGATC 
AGCATCGTGG AGCTGGAGAA GACCCAGCGC CAGCAGGAGC TCCTGCAGTT GAAGTCCTGT 
GTGCCACCAG ATGACGCTCT GTCCCTGCAC CTGCGTGGCA AGGGTGCCCT GGGCCGCGAG 
CTGGAGTCTG ACGCTGGGCG CTTGCGCCTT GAGCTGGACT GTGCCAAGCT CTCCCTCCCA 
CACCTCAGCA GCATGAGCCC TGAGCTGTCC ATGAATGGCC ATGCCGCCAG CTATGAGCTC 
TGCGGTGCAG CTAGTCGGCC CTCGTCCAAG CAGAACACCC CCCAGTATCT GGCCTCCCCC 
TTGGACCAGG AGGTCGTGCC CTGCACCCCT AGCCACAGTG GCCGGCCTCG GCTGGAGAAG 
CTGTCTGGCC TGGCTTTGCC TGACTACACC CGGTTGTCAC CGGCCAAGAT TGTGTTGAGG 
CGGCACCTGA GCCAGGACCA CACCGGGGCC AGCAAAGCAG CTACTAGTGA GCCACACCCT 
CGGCCAGAGC ATGCCAAGGA GAACAGCCTT CCCTACCAGA GCCCTGGCTT GTCGAACAGC 
ATGAAGCTCA GCCCCCAGGA TCCACCGCTG GCCTCCCCGG CAACCTCACC CCTCACTTCC 
GAGAGGGGTA GTGAGAAGGG TGTAAAGGAG CGTGCCTACA GCAGCCATGG GGAGACCATC 
ACCAGCCTGC CTGTCAGCAT TCCACTCAGC ACAGTACAGC CCAACAAGCT GCCTGTCAGC 
ATCCCGCTAG CCAGCGTGGT GCTGCCCAGC CGTGCCGAGA GGGCGAGGAG CACTCCCAGC 
CCTGTGCCCC AGCCTCGAGA CTCCTCATCC ACACTTGAGA AGCAGATTGG TGCTTCCACC 
CATGGTGCAG GGGGTGCTGC GGCAGGAAGC AGGAGCCTCA CTGTGGCGCC CACAGGTTTC 
TATGCTGGTT CGGTGGCCAT CAGTGGGGCT CTGGCCAGCA GCCCAGCACC TCTGGCCTCT 
GGAATGGAAT CTGCTGTTTT TGAGGAGTCC TCTGGCCCCA GCAGCCTCTT TGGCACCATG 
GGGTCTCGCA GCACACCGCC ACAACATCCA CCTCTCCTGC CGCAGTCTCG CAACTCGGGC 
CCTGCCTCTC CTGCCCACCA GCTCGCAGCC AGTCCCCGCC TGAGTGTGAC CACCCAGGGC 
TCACTGCCAG ACACCGGCAA AGGGGAGCTG CCTGCTGATC CTGCCTTCTC AGACCCAGAG 
AGTGAAGCTA AGAGGAGGAT TGTGTTCAGC ATTTCAGCTG GTGCCAGCTC CAGGCAGTCG 
CCTTCCACCA GGCACAGCCC CTTGACCTCT GGCACCCGTG GGGATTGTGT TCAGAGCCAT 
GGGCAGGACA GTCGTAAGCG TAGCAGAAGG AAGCGTGCAT CAGCTGGAAC GCCTAGCCTC 
ACCACGGGTG TGTCCCCCAA GCGCCGAGCT CTGCCAACCG TCGCTGGCCT CTTTACACAG 
TCTTCGGGGT CGCCTCTCAA TCTCACCTCC ATGGTCAGCA ACATCAACCA GCCCCTGGAG 
ATCACAGCCA TCTCATCCCC GGAGAGCTCA CTGAAGAGCT CCCCCACACC CTACCAGGAC 
CATGACCAGC CTCCAGTGCT CAGGAAGGAG CGGCCCCTGG GCCCAACTAA TGGGGCCCAC 
TACTCTCCGC TGACGTCAGA TGAGGAGCCA GGCTCGGAGG ACGAGCCCAG CAGTGCCCGA 
ATTGAGAGAA AAATTGCAAC AATCTCTTTA GAAAGCAAAT CTCCCCCGAA GACACTGGAA 
AATGGTGGTG GCTTAGTGGG AAGGAAGCCG GTCCCCTCAG GCGAGCCTGT CAACAGCAGC 
AAATGGAAGT CCACCTTCTC ACCCATCTCC GACCTCGGCT TGGCCAAGGC CATGGACAGT 
CCGCTACAGG CCAGCTCTGC ACTGAGCCAC AGCCCCCTCT TCTCTTTCCG GCCGTCCTTG 
GAGGAGCCTG CTGCTGAGGC CAAGCCCTCC ACCCACCCAA GGAAAAGTTT TGCGGGCTCT 
CTGGCTGCAG CTGAGGGGCC AAGCCCTGGC ACCAACCCTC CCAACAGCCT GGCCTTCAGT 
GGGGGCCTTG CTGCAGACCT CGGTTTACAT AGCTTCAATG ACGGTGCTTC CCTCTCCCAC 
AAGGGCCCGG AGGTGGCGGG CCTGAGCGCC TCCCTGAGCT TCCCATCCCA GAGGGGCAAG 
GACAGTACCA CAGAGGCCAA CCCCTTCCTC AGCAGGCGGC AGCCGGAGGG CCTGGGTGGC 
CTGAAGGGTG AGGGCAATGC AAGCAAGGAG TCAGGAGAGA GCCTGCCCCT GTGTGGGCCC 
TCAGACAAGG TCTCACTGCC ACACGGCAGC AGGGCCAGCA AAGGCCGTGA CCGCGAGCTG 
GACTTCAAGG GCGGCCACAA CCTCTTCATC TCTGCTGCAG CCGTGCCTCC AGGTGGCCTC 
CTTGGTGGCC CTGGTCTTGT AACTGTGGCT TCCTCTGCGG GCAGTGCGAC ACCCTCTGCC 
CAGGCTCCCC GGCCTTTCCT GAGCACCTTT GCCCCTGGGC CCCAGTTTAC TCTGGGCCCC 
ATGTCCCTGC AGGCCAACCT GGGCTCTGTG GCCGGCTCCT CTGTGCTGCA GTCCTTGTTC 
AGCACTGTGC CAGCTGCTGC AGGCCTGGTG CATGTGTCAT CCACTGCGAC CCGACTGACC 
AACTCACACA CCATGGGCAG CTTCTCCTCT GGGGTGGCCG GCGGAACCGT TGGAGGTGTC 
TTTACCCACG CGGTGCCCTC CGCCTCTGCT CACCCGTTTG GAGCTGGTGT CGGCAGCGGG 
GCTGTGTGTA GCAGTGCCAC GCTGGGCCTG AGCCCGCTGC AGGCGGCGGC CAGCACCTCG 
GCTTCTTCCT TTCAGGCCGC GGCTTCTGTT GAGACTCGGC CGCCCCCTCC ACCTCCCCTA 
CTTCCTCCTC AGCATCTCGG CCGGCCTCCT GCAGGGCCAC CTGTCCTCCA TGCACCCCCT 
CCTCCTAACG TCGCCTTGCC TCCTCCGCCT GCGCTGCTGG CTTCTAACCC TGAGCCAGTG 
CTTCTGCAGA GCCTGGCCTC CCTCCCGGCT AACAACGCTT TCTTACCCCC CTCCTCTGCC 
TCCTCTCTGC AGCCTGCTAA TGCCTCTCTA TCTGTCAAGC TCGCCTCCCT CCCACACAAG 
GTCTCCCGCC CCTCCTTCAC GGTGCACCAC CAGCCCCTGC CCCGGCTGGC CCTGGCGCAG 
GCCGCGCCCG CCGCACCACA GGCCAGCACC TCGGGGCCAT CTGCTGTGTG GGTTTCCCTT 
GGCATGCCGC CTCCTTATGC CGCGCACCTT TCAGGGGTTA AGCCTCGATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dot1l ( XM_006240959.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006241021.1 Rattus norvegicus DOT1 like histone lysine methyltransferase (Dot1l), transcript variant X1, mRNA.

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CloneID	ORa29886
Clone ID Related Accession (Same CDS sequence)	XM_006240960.3 , XM_006240959.3
Accession Version	XM_006240959.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5211bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006240959.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGCGAGA AGCTGGAGCT GAGGCTCAAG TCGCCTGTGG GCGCGGAGCC CGCCGTCTAC 
CCGTGGCCGC TGCCGGTCTA CGACAAGCAC CATGATGCTG CTCATGAGAT TATCGAGACT 
ATCCGATGGG TCTGCGAGGA AATCCCAGAT CTCAAGCTGG CCATGGAGAA CTATGTCCTG 
ATCGACTACG ACACCAAAAG TTTTGAAAGC ATGCAGAGGC TGTGTGACAA ATATAACCGG 
GCCATTGACA GCATCCACCA GCTGTGGAAG GGCACTACAC AGCCCATGAA GCTCAATACT 
CGGCCGTCCA ATGGGCTCCT GCGGCACATC CTGCAGCAGG TGTACAACCA CTCTGTGACC 
GACCCAGAGA AGCTCAACAA CTACGAGCCC TTCTCCCCCG AGGTGTACGG GGAGACCTCC 
TTTGACCTGG TGGCCCAGAT GATCGATGAG ATCAAGATGA CCGAGGATGA CCTGTTTGTA 
GACCTGGGCA GTGGTGTGGG GCAGGTTGTC CTTCAGGTTG CGGCGGCCAC CAACTGCAAA 
CATCACTACG GAGTGGAGAA AGCGGACATC CCAGCCAAGT ACGCGGAGAC CATGGATCGA 
GAGTTCAGGA AGTGGATGAA ATGGTATGGA AAAAAGCATG CAGAATACAC ACTGGAGCGA 
GGTGACTTCC TCTCAGAGGA GTGGAGGGAA CGGATCGCCA ACACGAGTGT TATATTTGTG 
AATAACTTTG CCTTTGGTCC TGAGGTGGAT CACCAGCTGA AGGAACGATT CGCAAACATG 
AAGGAAGGCG GCAGAATCGT ATCCTCAAAG CCCTTTGCCC CTCTGAACTT CAGGATCAAC 
AGCAGGAACT TGAGTGACAT TGGCACCATC ATGCGTGTGG TGGAGCTGTC GCCCCTGAAG 
GGCTCTGTGT CATGGACTGG CAAGCCTGTC TCCTACTACC TGCACACCAT TGACCGCACC 
ATACTTGAAA ACTATTTTTC TAGTCTGAAA AATCCAAAAC TCAGGGAGGA GCAGGAGGCA 
GCTAGGCGCA GGCAGCAGCG AGAGAACAAG AGCAACGCGA CCACACCCAC CAAAGTCCCT 
GAGAGCAAGG CAGCTGCCAC CGAGGCCCCT GCGGATTCTG GTGCTGAGGA AGAAAAATCA 
GGTGTGGCCA CCGTCAAAAA GCAATCTCCC TCCAAAGCCC GGAAGAAGAA ACTGAACAAG 
AAAGGGAGAA AAATGGCTGG CCGGAAGCGT GGGCGACCCA AGAAAATGAG TGCTGCCAGT 
GCCGATCGCA AGTCCAAGAA GAGCCAAAGC ACACTGGATC TCCTGCACTC TCCGCCCCCA 
GCCCCACCCT CAGCCTCACC CCAGGATGCA TACAGGGCCC CCCACAGCCC GTTCTACCAG 
CTACCTCCGA GCACGCCGCT GCACTCGCCC GACCCACTGC TAGTGGCTCC CACCCCACCC 
GCGCTGCAGA AGCTGTTAGA GTCCTTCAAG ATCCAGTACC TGCAGTTCCT GGCCTACACG 
AAGACCCCGC AGTACAAGGC CAACCTGCAG CAGCTTCTGG ACCAGGAGAA GGAGAAGAAC 
ACACAACTGC TGGGTACAGC CCAGCAGCTC TTCAGCCATT GCCAGGCACA AAAGGAAGAG 
ATCCGCAGGC TGTTCCAGCA GAAGCTGGAT GAGTTGGGCG TGAAGGCACT GACCTACAAT 
GACCTGATTC AGGCCCAGAA GGAAATCTCT GCCCACAACC AGCAGCTGCG GGAGCAGTCG 
GAACAGCTGG AGAAGGACAA CAGCGAGCTT CGGAGCCAGA GCCTGCGGCT GCTCAGGGCC 
CGGTGCGAAG AGCTGAGGCT TGACTGGTCC ACCTTGTCCC TGGAGAACCT GCGGAAAGAG 
AAGCAGGCCC TGCGGAGCCA GATCTCAGAG AAGCAGCGGC ACTGCCTAGA GCTGCAGATC 
AGCATCGTGG AGCTGGAGAA GACCCAGCGC CAGCAGGAGC TCCTGCAGTT GAAGTCCTGT 
GTGCCACCAG ATGACGCTCT GTCCCTGCAC CTGCGTGGCA AGGGTGCCCT GGGCCGCGAG 
CTGGAGTCTG ACGCTGGGCG CTTGCGCCTT GAGCTGGACT GTGCCAAGCT CTCCCTCCCA 
CACCTCAGCA GCATGAGCCC TGAGCTGTCC ATGAATGGCC ATGCCGCCAG CTATGAGCTC 
TGCGGTGCAG CTAGTCGGCC CTCGTCCAAG CAGAACACCC CCCAGTATCT GGCCTCCCCC 
TTGGACCAGG AGGTCGTGCC CTGCACCCCT AGCCACAGTG GCCGGCCTCG GCTGGAGAAG 
CTGTCTGGCC TGGCTTTGCC TGACTACACC CGGTTGTCAC CGGCCAAGAT TGTGTTGAGG 
CGGCACCTGA GCCAGGACCA CACCGGGGCC AGCAAAGCAG CTACTAGTGA GCCACACCCT 
CGGCCAGAGC ATGCCAAGGA GAACAGCCTT CCCTACCAGA GCCCTGGCTT GTCGAACAGC 
ATGAAGCTCA GCCCCCAGGA TCCACCGCTG GCCTCCCCGG CAACCTCACC CCTCACTTCC 
GAGAGGGGTA GTGAGAAGGG TGTAAAGGAG CGTGCCTACA GCAGCCATGG GGAGACCATC 
ACCAGCCTGC CTGTCAGCAT TCCACTCAGC ACAGTACAGC CCAACAAGCT GCCTGTCAGC 
ATCCCGCTAG CCAGCGTGGT GCTGCCCAGC CGTGCCGAGA GGGCGAGGAG CACTCCCAGC 
CCTGTGCCCC AGCCTCGAGA CTCCTCATCC ACACTTGAGA AGCAGATTGG TGCTTCCACC 
CATGGTGCAG GGGGTGCTGC GGCAGGAAGC AGGAGCCTCA CTGTGGCGCC CACAGGTTTC 
TATGCTGGTT CGGTGGCCAT CAGTGGGGCT CTGGCCAGCA GCCCAGCACC TCTGGCCTCT 
GGAATGGAAT CTGCTGTTTT TGAGGAGTCC TCTGGCCCCA GCAGCCTCTT TGGCACCATG 
GGGTCTCGCA GCACACCGCC ACAACATCCA CCTCTCCTGC CGCAGTCTCG CAACTCGGGC 
CCTGCCTCTC CTGCCCACCA GCTCGCAGCC AGTCCCCGCC TGAGTGTGAC CACCCAGGGC 
TCACTGCCAG ACACCGGCAA AGGGGAGCTG CCTGCTGATC CTGCCTTCTC AGACCCAGAG 
AGTGAAGCTA AGAGGAGGAT TGTGTTCAGC ATTTCAGCTG GTGCCAGCTC CAGGCAGTCG 
CCTTCCACCA GGCACAGCCC CTTGACCTCT GGCACCCGTG GGGATTGTGT TCAGAGCCAT 
GGGCAGGACA GTCGTAAGCG TAGCAGAAGG AAGCGTGCAT CAGCTGGAAC GCCTAGCCTC 
ACCACGGGTG TGTCCCCCAA GCGCCGAGCT CTGCCAACCG TCGCTGGCCT CTTTACACAG 
TCTTCGGGGT CGCCTCTCAA TCTCACCTCC ATGGTCAGCA ACATCAACCA GCCCCTGGAG 
ATCACAGCCA TCTCATCCCC GGAGAGCTCA CTGAAGAGCT CCCCCACACC CTACCAGGAC 
CATGACCAGC CTCCAGTGCT CAGGAAGGAG CGGCCCCTGG GCCCAACTAA TGGGGCCCAC 
TACTCTCCGC TGACGTCAGA TGAGGAGCCA GGCTCGGAGG ACGAGCCCAG CAGTGCCCGA 
ATTGAGAGAA AAATTGCAAC AATCTCTTTA GAAAGCAAAT CTCCCCCGAA GACACTGGAA 
AATGGTGGTG GCTTAGTGGG AAGGAAGCCG GTCCCCTCAG GCGAGCCTGT CAACAGCAGC 
AAATGGAAGT CCACCTTCTC ACCCATCTCC GACCTCGGCT TGGCCAAGGC CATGGACAGT 
CCGCTACAGG CCAGCTCTGC ACTGAGCCAC AGCCCCCTCT TCTCTTTCCG GCCGTCCTTG 
GAGGAGCCTG CTGCTGAGGC CAAGCCCTCC ACCCACCCAA GGAAAAGTTT TGCGGGCTCT 
CTGGCTGCAG CTGAGGGGCC AAGCCCTGGC ACCAACCCTC CCAACAGCCT GGCCTTCAGT 
GGGGGCCTTG CTGCAGACCT CGGTTTACAT AGCTTCAATG ACGGTGCTTC CCTCTCCCAC 
AAGGGCCCGG AGGTGGCGGG CCTGAGCGCC TCCCTGAGCT TCCCATCCCA GAGGGGCAAG 
GACAGTACCA CAGAGGCCAA CCCCTTCCTC AGCAGGCGGC AGCCGGAGGG CCTGGGTGGC 
CTGAAGGGTG AGGGCAATGC AAGCAAGGAG TCAGGAGAGA GCCTGCCCCT GTGTGGGCCC 
TCAGACAAGG TCTCACTGCC ACACGGCAGC AGGGCCAGCA AAGGCCGTGA CCGCGAGCTG 
GACTTCAAGG GCGGCCACAA CCTCTTCATC TCTGCTGCAG CCGTGCCTCC AGGTGGCCTC 
CTTGGTGGCC CTGGTCTTGT AACTGTGGCT TCCTCTGCGG GCAGTGCGAC ACCCTCTGCC 
CAGGCTCCCC GGCCTTTCCT GAGCACCTTT GCCCCTGGGC CCCAGTTTAC TCTGGGCCCC 
ATGTCCCTGC AGGCCAACCT GGGCTCTGTG GCCGGCTCCT CTGTGCTGCA GTCCTTGTTC 
AGCACTGTGC CAGCTGCTGC AGGCCTGGTG CATGTGTCAT CCACTGCGAC CCGACTGACC 
AACTCACACA CCATGGGCAG CTTCTCCTCT GGGGTGGCCG GCGGAACCGT TGGAGGTGTC 
TTTACCCACG CGGTGCCCTC CGCCTCTGCT CACCCGTTTG GAGCTGGTGT CGGCAGCGGG 
GCTGTGTGTA GCAGTGCCAC GCTGGGCCTG AGCCCGCTGC AGGCGGCGGC CAGCACCTCG 
GCTTCTTCCT TTCAGGCCGC GGCTTCTGTT GAGACTCGGC CGCCCCCTCC ACCTCCCCTA 
CTTCCTCCTC AGCATCTCGG CCGGCCTCCT GCAGGGCCAC CTGTCCTCCA TGCACCCCCT 
CCTCCTAACG TCGCCTTGCC TCCTCCGCCT GCGCTGCTGG CTTCTAACCC TGAGCCAGTG 
CTTCTGCAGA GCCTGGCCTC CCTCCCGGCT AACAACGCTT TCTTACCCCC CTCCTCTGCC 
TCCTCTCTGC AGCCTGCTAA TGCCTCTCTA TCTGTCAAGC TCGCCTCCCT CCCACACAAG 
GTCTCCCGCC CCTCCTTCAC GGTGCACCAC CAGCCCCTGC CCCGGCTGGC CCTGGCGCAG 
GCCGCGCCCG CCGCACCACA GGCCAGCACC TCGGGGCCAT CTGCTGTGTG GGTTTCCCTT 
GGCATGCCGC CTCCTTATGC CGCGCACCTT TCAGGGGTTA AGCCTCGATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006241021.1
CDS	235..5445
Translation	MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNATTPTKVPESKAAATEAPADSGAEEEKSGVATVKKQSPSKARKKKLNKKGRKMAGRKRGRPKKMSAASADRKSKKSQSTLDLLHSPPPAPPSASPQDAYRAPHSPFYQLPPSTPLHSPDPLLVAPTPPALQKLLESFKIQYLQFLAYTKTPQYKANLQQLLDQEKEKNTQLLGTAQQLFSHCQAQKEEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEKDNSELRSQSLRLLRARCEELRLDWSTLSLENLRKEKQALRSQISEKQRHCLELQISIVELEKTQRQQELLQLKSCVPPDDALSLHLRGKGALGRELESDAGRLRLELDCAKLSLPHLSSMSPELSMNGHAASYELCGAASRPSSKQNTPQYLASPLDQEVVPCTPSHSGRPRLEKLSGLALPDYTRLSPAKIVLRRHLSQDHTGASKAATSEPHPRPEHAKENSLPYQSPGLSNSMKLSPQDPPLASPATSPLTSERGSEKGVKERAYSSHGETITSLPVSIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPSPVPQPRDSSSTLEKQIGASTHGAGGAAAGSRSLTVAPTGFYAGSVAISGALASSPAPLASGMESAVFEESSGPSSLFGTMGSRSTPPQHPPLLPQSRNSGPASPAHQLAASPRLSVTTQGSLPDTGKGELPADPAFSDPESEAKRRIVFSISAGASSRQSPSTRHSPLTSGTRGDCVQSHGQDSRKRSRRKRASAGTPSLTTGVSPKRRALPTVAGLFTQSSGSPLNLTSMVSNINQPLEITAISSPESSLKSSPTPYQDHDQPPVLRKERPLGPTNGAHYSPLTSDEEPGSEDEPSSARIERKIATISLESKSPPKTLENGGGLVGRKPVPSGEPVNSSKWKSTFSPISDLGLAKAMDSPLQASSALSHSPLFSFRPSLEEPAAEAKPSTHPRKSFAGSLAAAEGPSPGTNPPNSLAFSGGLAADLGLHSFNDGASLSHKGPEVAGLSASLSFPSQRGKDSTTEANPFLSRRQPEGLGGLKGEGNASKESGESLPLCGPSDKVSLPHGSRASKGRDRELDFKGGHNLFISAAAVPPGGLLGGPGLVTVASSAGSATPSAQAPRPFLSTFAPGPQFTLGPMSLQANLGSVAGSSVLQSLFSTVPAAAGLVHVSSTATRLTNSHTMGSFSSGVAGGTVGGVFTHAVPSASAHPFGAGVGSGAVCSSATLGLSPLQAAASTSASSFQAAASVETRPPPPPPLLPPQHLGRPPAGPPVLHAPPPPNVALPPPPALLASNPEPVLLQSLASLPANNAFLPPSSASSLQPANASLSVKLASLPHKVSRPSFTVHHQPLPRLALAQAAPAAPQASTSGPSAVWVSLGMPPPYAAHLSGVKPR

Target ORF information:

RefSeq Version	XM_006240959.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus DOT1 like histone lysine methyltransferase (Dot1l), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006240959.3

ORF Insert Sequence:

ATGGGCGAGA AGCTGGAGCT GAGGCTCAAG TCGCCTGTGG GCGCGGAGCC CGCCGTCTAC 
CCGTGGCCGC TGCCGGTCTA CGACAAGCAC CATGATGCTG CTCATGAGAT TATCGAGACT 
ATCCGATGGG TCTGCGAGGA AATCCCAGAT CTCAAGCTGG CCATGGAGAA CTATGTCCTG 
ATCGACTACG ACACCAAAAG TTTTGAAAGC ATGCAGAGGC TGTGTGACAA ATATAACCGG 
GCCATTGACA GCATCCACCA GCTGTGGAAG GGCACTACAC AGCCCATGAA GCTCAATACT 
CGGCCGTCCA ATGGGCTCCT GCGGCACATC CTGCAGCAGG TGTACAACCA CTCTGTGACC 
GACCCAGAGA AGCTCAACAA CTACGAGCCC TTCTCCCCCG AGGTGTACGG GGAGACCTCC 
TTTGACCTGG TGGCCCAGAT GATCGATGAG ATCAAGATGA CCGAGGATGA CCTGTTTGTA 
GACCTGGGCA GTGGTGTGGG GCAGGTTGTC CTTCAGGTTG CGGCGGCCAC CAACTGCAAA 
CATCACTACG GAGTGGAGAA AGCGGACATC CCAGCCAAGT ACGCGGAGAC CATGGATCGA 
GAGTTCAGGA AGTGGATGAA ATGGTATGGA AAAAAGCATG CAGAATACAC ACTGGAGCGA 
GGTGACTTCC TCTCAGAGGA GTGGAGGGAA CGGATCGCCA ACACGAGTGT TATATTTGTG 
AATAACTTTG CCTTTGGTCC TGAGGTGGAT CACCAGCTGA AGGAACGATT CGCAAACATG 
AAGGAAGGCG GCAGAATCGT ATCCTCAAAG CCCTTTGCCC CTCTGAACTT CAGGATCAAC 
AGCAGGAACT TGAGTGACAT TGGCACCATC ATGCGTGTGG TGGAGCTGTC GCCCCTGAAG 
GGCTCTGTGT CATGGACTGG CAAGCCTGTC TCCTACTACC TGCACACCAT TGACCGCACC 
ATACTTGAAA ACTATTTTTC TAGTCTGAAA AATCCAAAAC TCAGGGAGGA GCAGGAGGCA 
GCTAGGCGCA GGCAGCAGCG AGAGAACAAG AGCAACGCGA CCACACCCAC CAAAGTCCCT 
GAGAGCAAGG CAGCTGCCAC CGAGGCCCCT GCGGATTCTG GTGCTGAGGA AGAAAAATCA 
GGTGTGGCCA CCGTCAAAAA GCAATCTCCC TCCAAAGCCC GGAAGAAGAA ACTGAACAAG 
AAAGGGAGAA AAATGGCTGG CCGGAAGCGT GGGCGACCCA AGAAAATGAG TGCTGCCAGT 
GCCGATCGCA AGTCCAAGAA GAGCCAAAGC ACACTGGATC TCCTGCACTC TCCGCCCCCA 
GCCCCACCCT CAGCCTCACC CCAGGATGCA TACAGGGCCC CCCACAGCCC GTTCTACCAG 
CTACCTCCGA GCACGCCGCT GCACTCGCCC GACCCACTGC TAGTGGCTCC CACCCCACCC 
GCGCTGCAGA AGCTGTTAGA GTCCTTCAAG ATCCAGTACC TGCAGTTCCT GGCCTACACG 
AAGACCCCGC AGTACAAGGC CAACCTGCAG CAGCTTCTGG ACCAGGAGAA GGAGAAGAAC 
ACACAACTGC TGGGTACAGC CCAGCAGCTC TTCAGCCATT GCCAGGCACA AAAGGAAGAG 
ATCCGCAGGC TGTTCCAGCA GAAGCTGGAT GAGTTGGGCG TGAAGGCACT GACCTACAAT 
GACCTGATTC AGGCCCAGAA GGAAATCTCT GCCCACAACC AGCAGCTGCG GGAGCAGTCG 
GAACAGCTGG AGAAGGACAA CAGCGAGCTT CGGAGCCAGA GCCTGCGGCT GCTCAGGGCC 
CGGTGCGAAG AGCTGAGGCT TGACTGGTCC ACCTTGTCCC TGGAGAACCT GCGGAAAGAG 
AAGCAGGCCC TGCGGAGCCA GATCTCAGAG AAGCAGCGGC ACTGCCTAGA GCTGCAGATC 
AGCATCGTGG AGCTGGAGAA GACCCAGCGC CAGCAGGAGC TCCTGCAGTT GAAGTCCTGT 
GTGCCACCAG ATGACGCTCT GTCCCTGCAC CTGCGTGGCA AGGGTGCCCT GGGCCGCGAG 
CTGGAGTCTG ACGCTGGGCG CTTGCGCCTT GAGCTGGACT GTGCCAAGCT CTCCCTCCCA 
CACCTCAGCA GCATGAGCCC TGAGCTGTCC ATGAATGGCC ATGCCGCCAG CTATGAGCTC 
TGCGGTGCAG CTAGTCGGCC CTCGTCCAAG CAGAACACCC CCCAGTATCT GGCCTCCCCC 
TTGGACCAGG AGGTCGTGCC CTGCACCCCT AGCCACAGTG GCCGGCCTCG GCTGGAGAAG 
CTGTCTGGCC TGGCTTTGCC TGACTACACC CGGTTGTCAC CGGCCAAGAT TGTGTTGAGG 
CGGCACCTGA GCCAGGACCA CACCGGGGCC AGCAAAGCAG CTACTAGTGA GCCACACCCT 
CGGCCAGAGC ATGCCAAGGA GAACAGCCTT CCCTACCAGA GCCCTGGCTT GTCGAACAGC 
ATGAAGCTCA GCCCCCAGGA TCCACCGCTG GCCTCCCCGG CAACCTCACC CCTCACTTCC 
GAGAGGGGTA GTGAGAAGGG TGTAAAGGAG CGTGCCTACA GCAGCCATGG GGAGACCATC 
ACCAGCCTGC CTGTCAGCAT TCCACTCAGC ACAGTACAGC CCAACAAGCT GCCTGTCAGC 
ATCCCGCTAG CCAGCGTGGT GCTGCCCAGC CGTGCCGAGA GGGCGAGGAG CACTCCCAGC 
CCTGTGCCCC AGCCTCGAGA CTCCTCATCC ACACTTGAGA AGCAGATTGG TGCTTCCACC 
CATGGTGCAG GGGGTGCTGC GGCAGGAAGC AGGAGCCTCA CTGTGGCGCC CACAGGTTTC 
TATGCTGGTT CGGTGGCCAT CAGTGGGGCT CTGGCCAGCA GCCCAGCACC TCTGGCCTCT 
GGAATGGAAT CTGCTGTTTT TGAGGAGTCC TCTGGCCCCA GCAGCCTCTT TGGCACCATG 
GGGTCTCGCA GCACACCGCC ACAACATCCA CCTCTCCTGC CGCAGTCTCG CAACTCGGGC 
CCTGCCTCTC CTGCCCACCA GCTCGCAGCC AGTCCCCGCC TGAGTGTGAC CACCCAGGGC 
TCACTGCCAG ACACCGGCAA AGGGGAGCTG CCTGCTGATC CTGCCTTCTC AGACCCAGAG 
AGTGAAGCTA AGAGGAGGAT TGTGTTCAGC ATTTCAGCTG GTGCCAGCTC CAGGCAGTCG 
CCTTCCACCA GGCACAGCCC CTTGACCTCT GGCACCCGTG GGGATTGTGT TCAGAGCCAT 
GGGCAGGACA GTCGTAAGCG TAGCAGAAGG AAGCGTGCAT CAGCTGGAAC GCCTAGCCTC 
ACCACGGGTG TGTCCCCCAA GCGCCGAGCT CTGCCAACCG TCGCTGGCCT CTTTACACAG 
TCTTCGGGGT CGCCTCTCAA TCTCACCTCC ATGGTCAGCA ACATCAACCA GCCCCTGGAG 
ATCACAGCCA TCTCATCCCC GGAGAGCTCA CTGAAGAGCT CCCCCACACC CTACCAGGAC 
CATGACCAGC CTCCAGTGCT CAGGAAGGAG CGGCCCCTGG GCCCAACTAA TGGGGCCCAC 
TACTCTCCGC TGACGTCAGA TGAGGAGCCA GGCTCGGAGG ACGAGCCCAG CAGTGCCCGA 
ATTGAGAGAA AAATTGCAAC AATCTCTTTA GAAAGCAAAT CTCCCCCGAA GACACTGGAA 
AATGGTGGTG GCTTAGTGGG AAGGAAGCCG GTCCCCTCAG GCGAGCCTGT CAACAGCAGC 
AAATGGAAGT CCACCTTCTC ACCCATCTCC GACCTCGGCT TGGCCAAGGC CATGGACAGT 
CCGCTACAGG CCAGCTCTGC ACTGAGCCAC AGCCCCCTCT TCTCTTTCCG GCCGTCCTTG 
GAGGAGCCTG CTGCTGAGGC CAAGCCCTCC ACCCACCCAA GGAAAAGTTT TGCGGGCTCT 
CTGGCTGCAG CTGAGGGGCC AAGCCCTGGC ACCAACCCTC CCAACAGCCT GGCCTTCAGT 
GGGGGCCTTG CTGCAGACCT CGGTTTACAT AGCTTCAATG ACGGTGCTTC CCTCTCCCAC 
AAGGGCCCGG AGGTGGCGGG CCTGAGCGCC TCCCTGAGCT TCCCATCCCA GAGGGGCAAG 
GACAGTACCA CAGAGGCCAA CCCCTTCCTC AGCAGGCGGC AGCCGGAGGG CCTGGGTGGC 
CTGAAGGGTG AGGGCAATGC AAGCAAGGAG TCAGGAGAGA GCCTGCCCCT GTGTGGGCCC 
TCAGACAAGG TCTCACTGCC ACACGGCAGC AGGGCCAGCA AAGGCCGTGA CCGCGAGCTG 
GACTTCAAGG GCGGCCACAA CCTCTTCATC TCTGCTGCAG CCGTGCCTCC AGGTGGCCTC 
CTTGGTGGCC CTGGTCTTGT AACTGTGGCT TCCTCTGCGG GCAGTGCGAC ACCCTCTGCC 
CAGGCTCCCC GGCCTTTCCT GAGCACCTTT GCCCCTGGGC CCCAGTTTAC TCTGGGCCCC 
ATGTCCCTGC AGGCCAACCT GGGCTCTGTG GCCGGCTCCT CTGTGCTGCA GTCCTTGTTC 
AGCACTGTGC CAGCTGCTGC AGGCCTGGTG CATGTGTCAT CCACTGCGAC CCGACTGACC 
AACTCACACA CCATGGGCAG CTTCTCCTCT GGGGTGGCCG GCGGAACCGT TGGAGGTGTC 
TTTACCCACG CGGTGCCCTC CGCCTCTGCT CACCCGTTTG GAGCTGGTGT CGGCAGCGGG 
GCTGTGTGTA GCAGTGCCAC GCTGGGCCTG AGCCCGCTGC AGGCGGCGGC CAGCACCTCG 
GCTTCTTCCT TTCAGGCCGC GGCTTCTGTT GAGACTCGGC CGCCCCCTCC ACCTCCCCTA 
CTTCCTCCTC AGCATCTCGG CCGGCCTCCT GCAGGGCCAC CTGTCCTCCA TGCACCCCCT 
CCTCCTAACG TCGCCTTGCC TCCTCCGCCT GCGCTGCTGG CTTCTAACCC TGAGCCAGTG 
CTTCTGCAGA GCCTGGCCTC CCTCCCGGCT AACAACGCTT TCTTACCCCC CTCCTCTGCC 
TCCTCTCTGC AGCCTGCTAA TGCCTCTCTA TCTGTCAAGC TCGCCTCCCT CCCACACAAG 
GTCTCCCGCC CCTCCTTCAC GGTGCACCAC CAGCCCCTGC CCCGGCTGGC CCTGGCGCAG 
GCCGCGCCCG CCGCACCACA GGCCAGCACC TCGGGGCCAT CTGCTGTGTG GGTTTCCCTT 
GGCATGCCGC CTCCTTATGC CGCGCACCTT TCAGGGGTTA AGCCTCGATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Dot1l ( XM_017594910.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017450399.1 Rattus norvegicus DOT1 like histone lysine methyltransferase (Dot1l), transcript variant X4, mRNA.

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CloneID	ORa62036
Clone ID Related Accession (Same CDS sequence)	XM_017594910.1
Accession Version	XM_017594910.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4563bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGGAGC GAGGTGACTT CCTCTCAGAG GAGTGGAGGG AACGGATCGC CAACACGAGT 
GTTATATTTG TGAATAACTT TGCCTTTGGT CCTGAGGTGG ATCACCAGCT GAAGGAACGA 
TTCGCAAACA TGAAGGAAGG CGGCAGAATC GTATCCTCAA AGCCCTTTGC CCCTCTGAAC 
TTCAGGATCA ACAGCAGGAA CTTGAGTGAC ATTGGCACCA TCATGCGTGT GGTGGAGCTG 
TCGCCCCTGA AGGGCTCTGT GTCATGGACT GGCAAGCCTG TCTCCTACTA CCTGCACACC 
ATTGACCGCA CCATACTTGA AAACTATTTT TCTAGTCTGA AAAATCCAAA ACTCAGGGAG 
GAGCAGGAGG CAGCTAGGCG CAGGCAGCAG CGAGAGAACA AGAGCAACGC GACCACACCC 
ACCAAAGTCC CTGAGAGCAA GGCAGCTGCC ACCGAGGCCC CTGCGGATTC TGGTGCTGAG 
GAAGAAAAAT CAGGTGTGGC CACCGTCAAA AAGCAATCTC CCTCCAAAGC CCGGAAGAAG 
AAACTGAACA AGAAAGGGAG AAAAATGGCT GGCCGGAAGC GTGGGCGACC CAAGAAAATG 
AGTGCTGCCA GTGCCGATCG CAAGTCCAAG AAGAGCCAAA GCACACTGGA TCTCCTGCAC 
TCTCCGCCCC CAGCCCCACC CTCAGCCTCA CCCCAGGATG CATACAGGGC CCCCCACAGC 
CCGTTCTACC AGCTACCTCC GAGCACGCCG CTGCACTCGC CCGACCCACT GCTAGTGGCT 
CCCACCCCAC CCGCGCTGCA GAAGCTGTTA GAGTCCTTCA AGATCCAGTA CCTGCAGTTC 
CTGGCCTACA CGAAGACCCC GCAGTACAAG GCCAACCTGC AGCAGCTTCT GGACCAGGAG 
AAGGAGAAGA ACACACAACT GCTGGGTACA GCCCAGCAGC TCTTCAGCCA TTGCCAGGCA 
CAAAAGGAAG AGATCCGCAG GCTGTTCCAG CAGAAGCTGG ATGAGTTGGG CGTGAAGGCA 
CTGACCTACA ATGACCTGAT TCAGGCCCAG AAGGAAATCT CTGCCCACAA CCAGCAGCTG 
CGGGAGCAGT CGGAACAGCT GGAGAAGGAC AACAGCGAGC TTCGGAGCCA GAGCCTGCGG 
CTGCTCAGGG CCCGGTGCGA AGAGCTGAGG CTTGACTGGT CCACCTTGTC CCTGGAGAAC 
CTGCGGAAAG AGAAGCAGGC CCTGCGGAGC CAGATCTCAG AGAAGCAGCG GCACTGCCTA 
GAGCTGCAGA TCAGCATCGT GGAGCTGGAG AAGACCCAGC GCCAGCAGGA GCTCCTGCAG 
TTGAAGTCCT GTGTGCCACC AGATGACGCT CTGTCCCTGC ACCTGCGTGG CAAGGGTGCC 
CTGGGCCGCG AGCTGGAGTC TGACGCTGGG CGCTTGCGCC TTGAGCTGGA CTGTGCCAAG 
CTCTCCCTCC CACACCTCAG CAGCATGAGC CCTGAGCTGT CCATGAATGG CCATGCCGCC 
AGCTATGAGC TCTGCGGTGC AGCTAGTCGG CCCTCGTCCA AGCAGAACAC CCCCCAGTAT 
CTGGCCTCCC CCTTGGACCA GGAGGTCGTG CCCTGCACCC CTAGCCACAG TGGCCGGCCT 
CGGCTGGAGA AGCTGTCTGG CCTGGCTTTG CCTGACTACA CCCGGTTGTC ACCGGCCAAG 
ATTGTGTTGA GGCGGCACCT GAGCCAGGAC CACACCGGGG CCAGCAAAGC AGCTACTAGT 
GAGCCACACC CTCGGCCAGA GCATGCCAAG GAGAACAGCC TTCCCTACCA GAGCCCTGGC 
TTGTCGAACA GCATGAAGCT CAGCCCCCAG GATCCACCGC TGGCCTCCCC GGCAACCTCA 
CCCCTCACTT CCGAGAGGGG TAGTGAGAAG GGTGTAAAGG AGCGTGCCTA CAGCAGCCAT 
GGGGAGACCA TCACCAGCCT GCCTGTCAGC ATTCCACTCA GCACAGTACA GCCCAACAAG 
CTGCCTGTCA GCATCCCGCT AGCCAGCGTG GTGCTGCCCA GCCGTGCCGA GAGGGCGAGG 
AGCACTCCCA GCCCTGTGCC CCAGCCTCGA GACTCCTCAT CCACACTTGA GAAGCAGATT 
GGTGCTTCCA CCCATGGTGC AGGGGGTGCT GCGGCAGGAA GCAGGAGCCT CACTGTGGCG 
CCCACAGGTT TCTATGCTGG TTCGGTGGCC ATCAGTGGGG CTCTGGCCAG CAGCCCAGCA 
CCTCTGGCCT CTGGAATGGA ATCTGCTGTT TTTGAGGAGT CCTCTGGCCC CAGCAGCCTC 
TTTGGCACCA TGGGGTCTCG CAGCACACCG CCACAACATC CACCTCTCCT GCCGCAGTCT 
CGCAACTCGG GCCCTGCCTC TCCTGCCCAC CAGCTCGCAG CCAGTCCCCG CCTGAGTGTG 
ACCACCCAGG GCTCACTGCC AGACACCGGC AAAGGGGAGC TGCCTGCTGA TCCTGCCTTC 
TCAGACCCAG AGAGTGAAGC TAAGAGGAGG ATTGTGTTCA GCATTTCAGC TGGTGCCAGC 
TCCAGGCAGT CGCCTTCCAC CAGGCACAGC CCCTTGACCT CTGGCACCCG TGGGGATTGT 
GTTCAGAGCC ATGGGCAGGA CAGTCGTAAG CGTAGCAGAA GGAAGCGTGC ATCAGCTGGA 
ACGCCTAGCC TCACCACGGG TGTGTCCCCC AAGCGCCGAG CTCTGCCAAC CGTCGCTGGC 
CTCTTTACAC AGTCTTCGGG GTCGCCTCTC AATCTCACCT CCATGGTCAG CAACATCAAC 
CAGCCCCTGG AGATCACAGC CATCTCATCC CCGGAGAGCT CACTGAAGAG CTCCCCCACA 
CCCTACCAGG ACCATGACCA GCCTCCAGTG CTCAGGAAGG AGCGGCCCCT GGGCCCAACT 
AATGGGGCCC ACTACTCTCC GCTGACGTCA GATGAGGAGC CAGGCTCGGA GGACGAGCCC 
AGCAGTGCCC GAATTGAGAG AAAAATTGCA ACAATCTCTT TAGAAAGCAA ATCTCCCCCG 
AAGACACTGG AAAATGGTGG TGGCTTAGTG GGAAGGAAGC CGGTCCCCTC AGGCGAGCCT 
GTCAACAGCA GCAAATGGAA GTCCACCTTC TCACCCATCT CCGACCTCGG CTTGGCCAAG 
GCCATGGACA GTCCGCTACA GGCCAGCTCT GCACTGAGCC ACAGCCCCCT CTTCTCTTTC 
CGGCCGTCCT TGGAGGAGCC TGCTGCTGAG GCCAAGCCCT CCACCCACCC AAGGAAAAGT 
TTTGCGGGCT CTCTGGCTGC AGCTGAGGGG CCAAGCCCTG GCACCAACCC TCCCAACAGC 
CTGGCCTTCA GTGGGGGCCT TGCTGCAGAC CTCGGTTTAC ATAGCTTCAA TGACGGTGCT 
TCCCTCTCCC ACAAGGGCCC GGAGGTGGCG GGCCTGAGCG CCTCCCTGAG CTTCCCATCC 
CAGAGGGGCA AGGACAGTAC CACAGAGGCC AACCCCTTCC TCAGCAGGCG GCAGCCGGAG 
GGCCTGGGTG GCCTGAAGGG TGAGGGCAAT GCAAGCAAGG AGTCAGGAGA GAGCCTGCCC 
CTGTGTGGGC CCTCAGACAA GGTCTCACTG CCACACGGCA GCAGGGCCAG CAAAGGCCGT 
GACCGCGAGC TGGACTTCAA GGGCGGCCAC AACCTCTTCA TCTCTGCTGC AGCCGTGCCT 
CCAGGTGGCC TCCTTGGTGG CCCTGGTCTT GTAACTGTGG CTTCCTCTGC GGGCAGTGCG 
ACACCCTCTG CCCAGGCTCC CCGGCCTTTC CTGAGCACCT TTGCCCCTGG GCCCCAGTTT 
ACTCTGGGCC CCATGTCCCT GCAGGCCAAC CTGGGCTCTG TGGCCGGCTC CTCTGTGCTG 
CAGTCCTTGT TCAGCACTGT GCCAGCTGCT GCAGGCCTGG TGCATGTGTC ATCCACTGCG 
ACCCGACTGA CCAACTCACA CACCATGGGC AGCTTCTCCT CTGGGGTGGC CGGCGGAACC 
GTTGGAGGTG TCTTTACCCA CGCGGTGCCC TCCGCCTCTG CTCACCCGTT TGGAGCTGGT 
GTCGGCAGCG GGGCTGTGTG TAGCAGTGCC ACGCTGGGCC TGAGCCCGCT GCAGGCGGCG 
GCCAGCACCT CGGCTTCTTC CTTTCAGGCC GCGGCTTCTG TTGAGACTCG GCCGCCCCCT 
CCACCTCCCC TACTTCCTCC TCAGCATCTC GGCCGGCCTC CTGCAGGGCC ACCTGTCCTC 
CATGCACCCC CTCCTCCTAA CGTCGCCTTG CCTCCTCCGC CTGCGCTGCT GGCTTCTAAC 
CCTGAGCCAG TGCTTCTGCA GAGCCTGGCC TCCCTCCCGG CTAACAACGC TTTCTTACCC 
CCCTCCTCTG CCTCCTCTCT GCAGCCTGCT AATGCCTCTC TATCTGTCAA GCTCGCCTCC 
CTCCCACACA AGGTCTCCCG CCCCTCCTTC ACGGTGCACC ACCAGCCCCT GCCCCGGCTG 
GCCCTGGCGC AGGCCGCGCC CGCCGCACCA CAGGCCAGCA CCTCGGGGCC ATCTGCTGTG 
TGGGTTTCCC TTGGCATGCC GCCTCCTTAT GCCGCGCACC TTTCAGGGGT TAAGCCTCGA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017450399.1
CDS	1323..5885
Translation	MLERGDFLSEEWRERIANTSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNATTPTKVPESKAAATEAPADSGAEEEKSGVATVKKQSPSKARKKKLNKKGRKMAGRKRGRPKKMSAASADRKSKKSQSTLDLLHSPPPAPPSASPQDAYRAPHSPFYQLPPSTPLHSPDPLLVAPTPPALQKLLESFKIQYLQFLAYTKTPQYKANLQQLLDQEKEKNTQLLGTAQQLFSHCQAQKEEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEKDNSELRSQSLRLLRARCEELRLDWSTLSLENLRKEKQALRSQISEKQRHCLELQISIVELEKTQRQQELLQLKSCVPPDDALSLHLRGKGALGRELESDAGRLRLELDCAKLSLPHLSSMSPELSMNGHAASYELCGAASRPSSKQNTPQYLASPLDQEVVPCTPSHSGRPRLEKLSGLALPDYTRLSPAKIVLRRHLSQDHTGASKAATSEPHPRPEHAKENSLPYQSPGLSNSMKLSPQDPPLASPATSPLTSERGSEKGVKERAYSSHGETITSLPVSIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPSPVPQPRDSSSTLEKQIGASTHGAGGAAAGSRSLTVAPTGFYAGSVAISGALASSPAPLASGMESAVFEESSGPSSLFGTMGSRSTPPQHPPLLPQSRNSGPASPAHQLAASPRLSVTTQGSLPDTGKGELPADPAFSDPESEAKRRIVFSISAGASSRQSPSTRHSPLTSGTRGDCVQSHGQDSRKRSRRKRASAGTPSLTTGVSPKRRALPTVAGLFTQSSGSPLNLTSMVSNINQPLEITAISSPESSLKSSPTPYQDHDQPPVLRKERPLGPTNGAHYSPLTSDEEPGSEDEPSSARIERKIATISLESKSPPKTLENGGGLVGRKPVPSGEPVNSSKWKSTFSPISDLGLAKAMDSPLQASSALSHSPLFSFRPSLEEPAAEAKPSTHPRKSFAGSLAAAEGPSPGTNPPNSLAFSGGLAADLGLHSFNDGASLSHKGPEVAGLSASLSFPSQRGKDSTTEANPFLSRRQPEGLGGLKGEGNASKESGESLPLCGPSDKVSLPHGSRASKGRDRELDFKGGHNLFISAAAVPPGGLLGGPGLVTVASSAGSATPSAQAPRPFLSTFAPGPQFTLGPMSLQANLGSVAGSSVLQSLFSTVPAAAGLVHVSSTATRLTNSHTMGSFSSGVAGGTVGGVFTHAVPSASAHPFGAGVGSGAVCSSATLGLSPLQAAASTSASSFQAAASVETRPPPPPPLLPPQHLGRPPAGPPVLHAPPPPNVALPPPPALLASNPEPVLLQSLASLPANNAFLPPSSASSLQPANASLSVKLASLPHKVSRPSFTVHHQPLPRLALAQAAPAAPQASTSGPSAVWVSLGMPPPYAAHLSGVKPR

Target ORF information:

RefSeq Version	XM_017594910.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus DOT1 like histone lysine methyltransferase (Dot1l), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017594910.1

ORF Insert Sequence:

ATGCTGGAGC GAGGTGACTT CCTCTCAGAG GAGTGGAGGG AACGGATCGC CAACACGAGT 
GTTATATTTG TGAATAACTT TGCCTTTGGT CCTGAGGTGG ATCACCAGCT GAAGGAACGA 
TTCGCAAACA TGAAGGAAGG CGGCAGAATC GTATCCTCAA AGCCCTTTGC CCCTCTGAAC 
TTCAGGATCA ACAGCAGGAA CTTGAGTGAC ATTGGCACCA TCATGCGTGT GGTGGAGCTG 
TCGCCCCTGA AGGGCTCTGT GTCATGGACT GGCAAGCCTG TCTCCTACTA CCTGCACACC 
ATTGACCGCA CCATACTTGA AAACTATTTT TCTAGTCTGA AAAATCCAAA ACTCAGGGAG 
GAGCAGGAGG CAGCTAGGCG CAGGCAGCAG CGAGAGAACA AGAGCAACGC GACCACACCC 
ACCAAAGTCC CTGAGAGCAA GGCAGCTGCC ACCGAGGCCC CTGCGGATTC TGGTGCTGAG 
GAAGAAAAAT CAGGTGTGGC CACCGTCAAA AAGCAATCTC CCTCCAAAGC CCGGAAGAAG 
AAACTGAACA AGAAAGGGAG AAAAATGGCT GGCCGGAAGC GTGGGCGACC CAAGAAAATG 
AGTGCTGCCA GTGCCGATCG CAAGTCCAAG AAGAGCCAAA GCACACTGGA TCTCCTGCAC 
TCTCCGCCCC CAGCCCCACC CTCAGCCTCA CCCCAGGATG CATACAGGGC CCCCCACAGC 
CCGTTCTACC AGCTACCTCC GAGCACGCCG CTGCACTCGC CCGACCCACT GCTAGTGGCT 
CCCACCCCAC CCGCGCTGCA GAAGCTGTTA GAGTCCTTCA AGATCCAGTA CCTGCAGTTC 
CTGGCCTACA CGAAGACCCC GCAGTACAAG GCCAACCTGC AGCAGCTTCT GGACCAGGAG 
AAGGAGAAGA ACACACAACT GCTGGGTACA GCCCAGCAGC TCTTCAGCCA TTGCCAGGCA 
CAAAAGGAAG AGATCCGCAG GCTGTTCCAG CAGAAGCTGG ATGAGTTGGG CGTGAAGGCA 
CTGACCTACA ATGACCTGAT TCAGGCCCAG AAGGAAATCT CTGCCCACAA CCAGCAGCTG 
CGGGAGCAGT CGGAACAGCT GGAGAAGGAC AACAGCGAGC TTCGGAGCCA GAGCCTGCGG 
CTGCTCAGGG CCCGGTGCGA AGAGCTGAGG CTTGACTGGT CCACCTTGTC CCTGGAGAAC 
CTGCGGAAAG AGAAGCAGGC CCTGCGGAGC CAGATCTCAG AGAAGCAGCG GCACTGCCTA 
GAGCTGCAGA TCAGCATCGT GGAGCTGGAG AAGACCCAGC GCCAGCAGGA GCTCCTGCAG 
TTGAAGTCCT GTGTGCCACC AGATGACGCT CTGTCCCTGC ACCTGCGTGG CAAGGGTGCC 
CTGGGCCGCG AGCTGGAGTC TGACGCTGGG CGCTTGCGCC TTGAGCTGGA CTGTGCCAAG 
CTCTCCCTCC CACACCTCAG CAGCATGAGC CCTGAGCTGT CCATGAATGG CCATGCCGCC 
AGCTATGAGC TCTGCGGTGC AGCTAGTCGG CCCTCGTCCA AGCAGAACAC CCCCCAGTAT 
CTGGCCTCCC CCTTGGACCA GGAGGTCGTG CCCTGCACCC CTAGCCACAG TGGCCGGCCT 
CGGCTGGAGA AGCTGTCTGG CCTGGCTTTG CCTGACTACA CCCGGTTGTC ACCGGCCAAG 
ATTGTGTTGA GGCGGCACCT GAGCCAGGAC CACACCGGGG CCAGCAAAGC AGCTACTAGT 
GAGCCACACC CTCGGCCAGA GCATGCCAAG GAGAACAGCC TTCCCTACCA GAGCCCTGGC 
TTGTCGAACA GCATGAAGCT CAGCCCCCAG GATCCACCGC TGGCCTCCCC GGCAACCTCA 
CCCCTCACTT CCGAGAGGGG TAGTGAGAAG GGTGTAAAGG AGCGTGCCTA CAGCAGCCAT 
GGGGAGACCA TCACCAGCCT GCCTGTCAGC ATTCCACTCA GCACAGTACA GCCCAACAAG 
CTGCCTGTCA GCATCCCGCT AGCCAGCGTG GTGCTGCCCA GCCGTGCCGA GAGGGCGAGG 
AGCACTCCCA GCCCTGTGCC CCAGCCTCGA GACTCCTCAT CCACACTTGA GAAGCAGATT 
GGTGCTTCCA CCCATGGTGC AGGGGGTGCT GCGGCAGGAA GCAGGAGCCT CACTGTGGCG 
CCCACAGGTT TCTATGCTGG TTCGGTGGCC ATCAGTGGGG CTCTGGCCAG CAGCCCAGCA 
CCTCTGGCCT CTGGAATGGA ATCTGCTGTT TTTGAGGAGT CCTCTGGCCC CAGCAGCCTC 
TTTGGCACCA TGGGGTCTCG CAGCACACCG CCACAACATC CACCTCTCCT GCCGCAGTCT 
CGCAACTCGG GCCCTGCCTC TCCTGCCCAC CAGCTCGCAG CCAGTCCCCG CCTGAGTGTG 
ACCACCCAGG GCTCACTGCC AGACACCGGC AAAGGGGAGC TGCCTGCTGA TCCTGCCTTC 
TCAGACCCAG AGAGTGAAGC TAAGAGGAGG ATTGTGTTCA GCATTTCAGC TGGTGCCAGC 
TCCAGGCAGT CGCCTTCCAC CAGGCACAGC CCCTTGACCT CTGGCACCCG TGGGGATTGT 
GTTCAGAGCC ATGGGCAGGA CAGTCGTAAG CGTAGCAGAA GGAAGCGTGC ATCAGCTGGA 
ACGCCTAGCC TCACCACGGG TGTGTCCCCC AAGCGCCGAG CTCTGCCAAC CGTCGCTGGC 
CTCTTTACAC AGTCTTCGGG GTCGCCTCTC AATCTCACCT CCATGGTCAG CAACATCAAC 
CAGCCCCTGG AGATCACAGC CATCTCATCC CCGGAGAGCT CACTGAAGAG CTCCCCCACA 
CCCTACCAGG ACCATGACCA GCCTCCAGTG CTCAGGAAGG AGCGGCCCCT GGGCCCAACT 
AATGGGGCCC ACTACTCTCC GCTGACGTCA GATGAGGAGC CAGGCTCGGA GGACGAGCCC 
AGCAGTGCCC GAATTGAGAG AAAAATTGCA ACAATCTCTT TAGAAAGCAA ATCTCCCCCG 
AAGACACTGG AAAATGGTGG TGGCTTAGTG GGAAGGAAGC CGGTCCCCTC AGGCGAGCCT 
GTCAACAGCA GCAAATGGAA GTCCACCTTC TCACCCATCT CCGACCTCGG CTTGGCCAAG 
GCCATGGACA GTCCGCTACA GGCCAGCTCT GCACTGAGCC ACAGCCCCCT CTTCTCTTTC 
CGGCCGTCCT TGGAGGAGCC TGCTGCTGAG GCCAAGCCCT CCACCCACCC AAGGAAAAGT 
TTTGCGGGCT CTCTGGCTGC AGCTGAGGGG CCAAGCCCTG GCACCAACCC TCCCAACAGC 
CTGGCCTTCA GTGGGGGCCT TGCTGCAGAC CTCGGTTTAC ATAGCTTCAA TGACGGTGCT 
TCCCTCTCCC ACAAGGGCCC GGAGGTGGCG GGCCTGAGCG CCTCCCTGAG CTTCCCATCC 
CAGAGGGGCA AGGACAGTAC CACAGAGGCC AACCCCTTCC TCAGCAGGCG GCAGCCGGAG 
GGCCTGGGTG GCCTGAAGGG TGAGGGCAAT GCAAGCAAGG AGTCAGGAGA GAGCCTGCCC 
CTGTGTGGGC CCTCAGACAA GGTCTCACTG CCACACGGCA GCAGGGCCAG CAAAGGCCGT 
GACCGCGAGC TGGACTTCAA GGGCGGCCAC AACCTCTTCA TCTCTGCTGC AGCCGTGCCT 
CCAGGTGGCC TCCTTGGTGG CCCTGGTCTT GTAACTGTGG CTTCCTCTGC GGGCAGTGCG 
ACACCCTCTG CCCAGGCTCC CCGGCCTTTC CTGAGCACCT TTGCCCCTGG GCCCCAGTTT 
ACTCTGGGCC CCATGTCCCT GCAGGCCAAC CTGGGCTCTG TGGCCGGCTC CTCTGTGCTG 
CAGTCCTTGT TCAGCACTGT GCCAGCTGCT GCAGGCCTGG TGCATGTGTC ATCCACTGCG 
ACCCGACTGA CCAACTCACA CACCATGGGC AGCTTCTCCT CTGGGGTGGC CGGCGGAACC 
GTTGGAGGTG TCTTTACCCA CGCGGTGCCC TCCGCCTCTG CTCACCCGTT TGGAGCTGGT 
GTCGGCAGCG GGGCTGTGTG TAGCAGTGCC ACGCTGGGCC TGAGCCCGCT GCAGGCGGCG 
GCCAGCACCT CGGCTTCTTC CTTTCAGGCC GCGGCTTCTG TTGAGACTCG GCCGCCCCCT 
CCACCTCCCC TACTTCCTCC TCAGCATCTC GGCCGGCCTC CTGCAGGGCC ACCTGTCCTC 
CATGCACCCC CTCCTCCTAA CGTCGCCTTG CCTCCTCCGC CTGCGCTGCT GGCTTCTAAC 
CCTGAGCCAG TGCTTCTGCA GAGCCTGGCC TCCCTCCCGG CTAACAACGC TTTCTTACCC 
CCCTCCTCTG CCTCCTCTCT GCAGCCTGCT AATGCCTCTC TATCTGTCAA GCTCGCCTCC 
CTCCCACACA AGGTCTCCCG CCCCTCCTTC ACGGTGCACC ACCAGCCCCT GCCCCGGCTG 
GCCCTGGCGC AGGCCGCGCC CGCCGCACCA CAGGCCAGCA CCTCGGGGCC ATCTGCTGTG 
TGGGTTTCCC TTGGCATGCC GCCTCCTTAT GCCGCGCACC TTTCAGGGGT TAAGCCTCGA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Potent inhibition of DOT1L as treatment of MLL-fusion leukemia.
Blood122(6)1017-25(2013 Aug)
Daigle SR,Olhava EJ,Therkelsen CA,Basavapathruni A,Jin L,Boriack-Sjodin PA,Allain CJ,Klaus CR,Raimondi A,Scott MP,Waters NJ,Chesworth R,Moyer MP,Copeland RA,Richon VM,Pollock RM

Histone lysine methylation dynamics: establishment, regulation, and biological impact.
Molecular cell48(4)491-507(2012 Nov)
Black JC,Van Rechem C,Whetstine JR

Targeting protein lysine methylation and demethylation in cancers.
Acta biochimica et biophysica Sinica44(1)70-9(2012 Jan)
He Y,Korboukh I,Jin J,Huang J

A novel disrupter of telomere silencing 1-like (DOT1L) interaction is required for signal transducer and activator of transcription 1 (STAT1)-activated gene expression.
The Journal of biological chemistry286(48)41195-204(2011 Dec)
Shah S,Henriksen MA

Modulation of p53 function by SET8-mediated methylation at lysine 382.
Molecular cell27(4)636-46(2007 Aug)
Shi X,Kachirskaia I,Yamaguchi H,West LE,Wen H,Wang EW,Dutta S,Appella E,Gozani O

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Dot1l cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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