Lsm7 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lsm7
Entrez Gene ID	362829
Full Name	LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
General protein information	Preferred Names LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated Names U6 snRNA-associated Sm-like protein LSm7 LSM7 U6 small nuclear RNA and mRNA degradation associated LSM7 homolog, U6 small nuclear RNA associated
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q11

mRNA and Protein(s)

mRNA	Protein	Name
XM_006240958.3	XP_006241020.1	U6 snRNA-associated Sm-like protein LSm7 isoform X1
NM_001108732.1	NP_001102202.1	U6 snRNA-associated Sm-like protein LSm7
XM_008765118.2	XP_008763340.1	U6 snRNA-associated Sm-like protein LSm7 isoform X2
XM_017594909.1	XP_017450398.1	U6 snRNA-associated Sm-like protein LSm7 isoform X3

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LSM7	XP_512258.2
Bos taurus (cattle)	LSM7	NP_001137334.1
Mus musculus (house mouse)	Lsm7	NP_079625.1
Rattus norvegicus (Norway rat)	Lsm7	NP_001102202.1
Caenorhabditis elegans (roundworm)	lsm-7	NP_502034.1
Schizosaccharomyces pombe (fission yeast)	lsm7	NP_588340.1
Magnaporthe oryzae (rice blast fungus)	MGG_02938	XP_003720770.1
Oryza sativa (rice)	Os08g0177700	NP_001061124.1
Homo sapiens (human)	LSM7	NP_057283.1
Canis lupus familiaris (dog)	LSM7	XP_854995.1
Drosophila melanogaster (fruit fly)	LSm7	NP_001246045.1
Saccharomyces cerevisiae (baker's yeast)	LSM7	NP_014252.2
Eremothecium gossypii	AGOS_AFR053C	NP_985600.2
Arabidopsis thaliana (thale cress)	AT2G03870	NP_849931.1
Xenopus tropicalis (tropical clawed frog)	lsm7	NP_001165133.1
Gallus gallus (chicken)	LSM7	NP_001006337.1
Danio rerio (zebrafish)	lsm7	NP_001041471.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008122	XP_317337.3
Kluyveromyces lactis	KLLA0E22881g	XP_454984.1

Gene Ontology
Bibliography

Related articles in PubMed

Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.
Bertram K, Agafonov DE, Dybkov O, Haselbach D, Leelaram MN, Will CL, Urlaub H, Kastner B, L?hrmann R, Stark H
Cell170(4)701-713.e11(2017 Aug)

Molecular architecture of the human U4/U6.U5 tri-snRNP.
Agafonov DE, Kastner B, Dybkov O, Hofele RV, Liu WT, Urlaub H, L?hrmann R, Stark H
Science (New York, N.Y.)351(6280)1416-20(2016 Mar)

The spliceosome: design principles of a dynamic RNP machine.
Wahl MC, Will CL, L?hrmann R
Cell136(4)701-18(2009 Feb)

Proteomic analysis of in vivo-assembled pre-mRNA splicing complexes expands the catalog of participating factors.
Chen YI, Moore RE, Ge HY, Young MK, Lee TD, Stevens SW
Nucleic acids research35(12)3928-44(2007)

A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro.
Achsel T, Brahms H, Kastner B, Bachi A, Wilm M, L?hrmann R
The EMBO journal18(20)5789-802(1999 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Lsm7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lsm7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa08226	NM_001108732.1 Latest version!	Rattus norvegicus LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated (Lsm7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa29885	XM_006240958.3 Latest version!	Rattus norvegicus LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated (Lsm7), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa48372	XM_008765118.2 Latest version!	Rattus norvegicus LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated (Lsm7), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa62035	XM_017594909.1 Latest version!	Rattus norvegicus LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated (Lsm7), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lsm7 ( NM_001108732.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001102202.1 Rattus norvegicus LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated (Lsm7), mRNA.

Price & Availability↑

CloneID	ORa08226
Clone ID Related Accession (Same CDS sequence)	NM_001108732.1
Accession Version	NM_001108732.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 312bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	U6 snRNA-associated Sm-like protein LSm7
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH474029.1. On or before Oct 4, 2007 this sequence version replaced XM_343157.3, XM_001076086.1. ##Evidence-Data-START## Transcript exon combination :: CB313941.1, FM058686.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGACA AAGAGAAAAA GAAGAAAGAA AGCATCTTGG ACCTGTCCAA GTATATTGAT 
AAGACCATTC GAGTCAAGTT CCAGGGTGGC CGGGAAGCCA GCGGCATCCT GAAAGGGTTT 
GACCCACTGC TCAACCTGGT GCTGGATGGG ACCATTGAAT ACATGCGAGA CCCCGATGAC 
CAGTACAAGC TGACAGAGGA CACTCGGCAG CTGGGGCTCG TAGTGTGCCG TGGCACCTCG 
GTGGTGCTCA TCTGCCCGCA GGATGGCATG GAGGCCATCC CTAACCCCTT TGTGCAGCAG 
CAGGACACTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001102202.1
CDS	29..340
Translation	MADKEKKKKESILDLSKYIDKTIRVKFQGGREASGILKGFDPLLNLVLDGTIEYMRDPDDQYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFVQQQDT

Target ORF information:

RefSeq Version	NM_001108732.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated (Lsm7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108732.1

ORF Insert Sequence:

ATGGCGGACA AAGAGAAAAA GAAGAAAGAA AGCATCTTGG ACCTGTCCAA GTATATTGAT 
AAGACCATTC GAGTCAAGTT CCAGGGTGGC CGGGAAGCCA GCGGCATCCT GAAAGGGTTT 
GACCCACTGC TCAACCTGGT GCTGGATGGG ACCATTGAAT ACATGCGAGA CCCCGATGAC 
CAGTACAAGC TGACAGAGGA CACTCGGCAG CTGGGGCTCG TAGTGTGCCG TGGCACCTCG 
GTGGTGCTCA TCTGCCCGCA GGATGGCATG GAGGCCATCC CTAACCCCTT TGTGCAGCAG 
CAGGACACTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lsm7 ( XM_006240958.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006241020.1 Rattus norvegicus LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated (Lsm7), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa29885
Clone ID Related Accession (Same CDS sequence)	XM_006240958.3
Accession Version	XM_006240958.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 330bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	U6 snRNA-associated Sm-like protein LSm7 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006240958.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGCGTC CCACCTTCCA GCAGGACAAA GAGAAAAAGA AGAAAGAAAG CATCTTGGAC 
CTGTCCAAGT ATATTGATAA GACCATTCGA GTCAAGTTCC AGGGTGGCCG GGAAGCCAGC 
GGCATCCTGA AAGGGTTTGA CCCACTGCTC AACCTGGTGC TGGATGGGAC CATTGAATAC 
ATGCGAGACC CCGATGACCA GTACAAGCTG ACAGAGGACA CTCGGCAGCT GGGGCTCGTA 
GTGTGCCGTG GCACCTCGGT GGTGCTCATC TGCCCGCAGG ATGGCATGGA GGCCATCCCT 
AACCCCTTTG TGCAGCAGCA GGACACTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006241020.1
CDS	22..351
Translation	MARPTFQQDKEKKKKESILDLSKYIDKTIRVKFQGGREASGILKGFDPLLNLVLDGTIEYMRDPDDQYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFVQQQDT

Target ORF information:

RefSeq Version	XM_006240958.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated (Lsm7), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006240958.3

ORF Insert Sequence:

ATGGCGCGTC CCACCTTCCA GCAGGACAAA GAGAAAAAGA AGAAAGAAAG CATCTTGGAC 
CTGTCCAAGT ATATTGATAA GACCATTCGA GTCAAGTTCC AGGGTGGCCG GGAAGCCAGC 
GGCATCCTGA AAGGGTTTGA CCCACTGCTC AACCTGGTGC TGGATGGGAC CATTGAATAC 
ATGCGAGACC CCGATGACCA GTACAAGCTG ACAGAGGACA CTCGGCAGCT GGGGCTCGTA 
GTGTGCCGTG GCACCTCGGT GGTGCTCATC TGCCCGCAGG ATGGCATGGA GGCCATCCCT 
AACCCCTTTG TGCAGCAGCA GGACACTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lsm7 ( XM_008765118.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008763340.1 Rattus norvegicus LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated (Lsm7), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa48372
Clone ID Related Accession (Same CDS sequence)	XM_008765118.2
Accession Version	XM_008765118.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 315bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	U6 snRNA-associated Sm-like protein LSm7 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008765118.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGCAGG ACAAAGAGAA AAAGAAGAAA GAAAGCATCT TGGACCTGTC CAAGTATATT 
GATAAGACCA TTCGAGTCAA GTTCCAGGGT GGCCGGGAAG CCAGCGGCAT CCTGAAAGGG 
TTTGACCCAC TGCTCAACCT GGTGCTGGAT GGGACCATTG AATACATGCG AGACCCCGAT 
GACCAGTACA AGCTGACAGA GGACACTCGG CAGCTGGGGC TCGTAGTGTG CCGTGGCACC 
TCGGTGGTGC TCATCTGCCC GCAGGATGGC ATGGAGGCCA TCCCTAACCC CTTTGTGCAG 
CAGCAGGACA CTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008763340.1
CDS	59..373
Translation	MAQDKEKKKKESILDLSKYIDKTIRVKFQGGREASGILKGFDPLLNLVLDGTIEYMRDPDDQYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFVQQQDT

Target ORF information:

RefSeq Version	XM_008765118.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated (Lsm7), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008765118.2

ORF Insert Sequence:

ATGGCGCAGG ACAAAGAGAA AAAGAAGAAA GAAAGCATCT TGGACCTGTC CAAGTATATT 
GATAAGACCA TTCGAGTCAA GTTCCAGGGT GGCCGGGAAG CCAGCGGCAT CCTGAAAGGG 
TTTGACCCAC TGCTCAACCT GGTGCTGGAT GGGACCATTG AATACATGCG AGACCCCGAT 
GACCAGTACA AGCTGACAGA GGACACTCGG CAGCTGGGGC TCGTAGTGTG CCGTGGCACC 
TCGGTGGTGC TCATCTGCCC GCAGGATGGC ATGGAGGCCA TCCCTAACCC CTTTGTGCAG 
CAGCAGGACA CTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lsm7 ( XM_017594909.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017450398.1 Rattus norvegicus LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated (Lsm7), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa62035
Clone ID Related Accession (Same CDS sequence)	XM_017594909.1
Accession Version	XM_017594909.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 282bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	U6 snRNA-associated Sm-like protein LSm7 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGCGTC CCACCTTCCA GCAGGACAAA GAGAAAAAGA AGAAAGAAAG CATCTTGGAC 
CTGTCCAAGT ATATTGATAA GACCATTCGA GTCAAGTTCC AGGGTGGCCG GGAAGCCAGC 
GGCATCCTGA AAGGGTTTGA CCCACTGCTC AACCTGGTGC TGGATGGGAC CATTGAATAC 
ATGCGAGGGA CGTCCCAGAC AGGCAAAGGG AGCCCCGGCG CAGCTCCAGA AGGACCCAGA 
TGGCTCTTCA TAGAACAGGG CCTGTTGCCA CCTACACTCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017450398.1
CDS	30..311
Translation	MARPTFQQDKEKKKKESILDLSKYIDKTIRVKFQGGREASGILKGFDPLLNLVLDGTIEYMRGTSQTGKGSPGAAPEGPRWLFIEQGLLPPTL

Target ORF information:

RefSeq Version	XM_017594909.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated (Lsm7), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017594909.1

ORF Insert Sequence:

ATGGCGCGTC CCACCTTCCA GCAGGACAAA GAGAAAAAGA AGAAAGAAAG CATCTTGGAC 
CTGTCCAAGT ATATTGATAA GACCATTCGA GTCAAGTTCC AGGGTGGCCG GGAAGCCAGC 
GGCATCCTGA AAGGGTTTGA CCCACTGCTC AACCTGGTGC TGGATGGGAC CATTGAATAC 
ATGCGAGGGA CGTCCCAGAC AGGCAAAGGG AGCCCCGGCG CAGCTCCAGA AGGACCCAGA 
TGGCTCTTCA TAGAACAGGG CCTGTTGCCA CCTACACTCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.
Cell170(4)701-713.e11(2017 Aug)
Bertram K,Agafonov DE,Dybkov O,Haselbach D,Leelaram MN,Will CL,Urlaub H,Kastner B,L?hrmann R,Stark H

Molecular architecture of the human U4/U6.U5 tri-snRNP.
Science (New York, N.Y.)351(6280)1416-20(2016 Mar)
Agafonov DE,Kastner B,Dybkov O,Hofele RV,Liu WT,Urlaub H,L?hrmann R,Stark H

The spliceosome: design principles of a dynamic RNP machine.
Cell136(4)701-18(2009 Feb)
Wahl MC,Will CL,L?hrmann R

Proteomic analysis of in vivo-assembled pre-mRNA splicing complexes expands the catalog of participating factors.
Nucleic acids research35(12)3928-44(2007)
Chen YI,Moore RE,Ge HY,Young MK,Lee TD,Stevens SW

A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro.
The EMBO journal18(20)5789-802(1999 Oct)
Achsel T,Brahms H,Kastner B,Bachi A,Wilm M,L?hrmann R

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Lsm7 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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