Sppl2b cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Sppl2b
Entrez Gene ID	362828
Full Name	signal peptide peptidase-like 2B
Synonyms	RGD1308556
General protein information	Preferred Names signal peptide peptidase-like 2B Names signal peptide peptidase-like 2B SPP-like 2B presenilin-like protein 1 protein SPP-like 2B protein SPPL2b
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q11

mRNA and Protein(s)

mRNA	Protein	Name
XM_006240948.3	XP_006241010.1	signal peptide peptidase-like 2B isoform X6
XM_008765116.2	XP_008763338.2	signal peptide peptidase-like 2B isoform X7
XM_017594908.1	XP_017450397.1	signal peptide peptidase-like 2B isoform X4
NM_001014200.1	NP_001014222.1	signal peptide peptidase-like 2B precursor
XM_008765111.2	XP_008763333.1	signal peptide peptidase-like 2B isoform X1
XM_008765112.2	XP_008763334.1	signal peptide peptidase-like 2B isoform X2
XM_008765110.2	XP_008763332.2	signal peptide peptidase-like 2B isoform X3
XM_006240947.3	XP_006241009.1	signal peptide peptidase-like 2B isoform X5

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	sppl2	NP_001015067.1
Homo sapiens (human)	SPPL2B	NP_694533.1
Canis lupus familiaris (dog)	SPPL2B	XP_542189.4
Mus musculus (house mouse)	Sppl2b	NP_780404.2
Rattus norvegicus (Norway rat)	Sppl2b	NP_001014222.1
Arabidopsis thaliana (thale cress)	SPPL5	NP_172073.2
Xenopus tropicalis (tropical clawed frog)	sppl2b	NP_001072874.1
Pan troglodytes (chimpanzee)	SPPL2B	XP_003316040.2
Bos taurus (cattle)	SPPL2B	XP_002689000.2
Arabidopsis thaliana (thale cress)	SPPL3	NP_850383.2
Oryza sativa (rice)	Os01g0914700	NP_001045182.1
Gallus gallus (chicken)	SPPL2B	NP_001026104.1

Gene Ontology
Bibliography

Related articles in PubMed

The ?-helical content of the transmembrane domain of the British dementia protein-2 (Bri2) determines its processing by signal peptide peptidase-like 2b (SPPL2b).
Fluhrer R, Martin L, Klier B, Haug-Kr?per M, Grammer G, Nuscher B, Haass C
The Journal of biological chemistry287(7)5156-63(2012 Feb)

Signal-peptide-peptidase-like 2a (SPPL2a) is targeted to lysosomes/late endosomes by a tyrosine motif in its C-terminal tail.
Behnke J, Schneppenheim J, Koch-Nolte F, Haag F, Saftig P, Schr?der B
FEBS letters585(19)2951-7(2011 Oct)

Substrate requirements for SPPL2b-dependent regulated intramembrane proteolysis.
Martin L, Fluhrer R, Haass C
The Journal of biological chemistry284(9)5662-70(2009 Feb)

Regulated intramembrane proteolysis of Bri2 (Itm2b) by ADAM10 and SPPL2a/SPPL2b.
Martin L, Fluhrer R, Reiss K, Kremmer E, Saftig P, Haass C
The Journal of biological chemistry283(3)1644-52(2008 Jan)

Intramembrane proteolytic cleavage by human signal peptide peptidase like 3 and malaria signal peptide peptidase.
Nyborg AC, Ladd TB, Jansen K, Kukar T, Golde TE
FASEB journal : official publication of the Federation of American Societies for Experimental Biology20(10)1671-9(2006 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Sppl2b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sppl2b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa05372	NM_001014200.1 Latest version!	Rattus norvegicus signal peptide peptidase-like 2B (Sppl2b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
ORa29876	XM_006240947.3 Latest version!	Rattus norvegicus signal peptide peptidase-like 2B (Sppl2b), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa29877	XM_006240948.3 Latest version!	Rattus norvegicus signal peptide peptidase-like 2B (Sppl2b), transcript variant X6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa48366	XM_008765111.2 Latest version!	Rattus norvegicus signal peptide peptidase-like 2B (Sppl2b), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa48367	XM_008765112.2 Latest version!	Rattus norvegicus signal peptide peptidase-like 2B (Sppl2b), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa62032	XM_008765110.2 Latest version!	Rattus norvegicus signal peptide peptidase-like 2B (Sppl2b), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
ORa62033	XM_017594908.1 Latest version!	Rattus norvegicus signal peptide peptidase-like 2B (Sppl2b), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
ORa62034	XM_008765116.2 Latest version!	Rattus norvegicus signal peptide peptidase-like 2B (Sppl2b), transcript variant X8, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Sppl2b ( NM_001014200.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001014222.1 Rattus norvegicus signal peptide peptidase-like 2B (Sppl2b), mRNA.

Price & Availability↑

CloneID	ORa05372
Clone ID Related Accession (Same CDS sequence)	NM_001014200.1
Accession Version	NM_001014200.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1734bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-18
Organism	Rattus norvegicus(Norway rat)
Product	signal peptide peptidase-like 2B precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC087132.1. On Apr 20, 2005 this sequence version replaced XM_343156.2. ##Evidence-Data-START## Transcript exon combination :: BC087132.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCGGCGG CGCGGCTGGC CGCATCCCTG CTGCTACTCG CGGCCCAGGT GGCCTGTGAG 
TTCGGTGTAC TGCGAGTTGT GCCCCAAAGC GGTGGGACCC GGGGCAGGGA CTACTGCATC 
CTTTACAACC CACAGTGGGC CCACTTGCCT CATGACCTCA ACAAAGTGTC TCTTCTGAAG 
CTTCGAGACT TGAGCACGAC TCAGCTCTGT TCCCACCTCG ATGTTCCTGT AGAAGACTTC 
ACCAACCAGA TCGCACTGGT GGCTCGGGGC AACTGTACCT TCTATGAGAA AGTGCGGCTG 
GCCCAGGGCA GTGGGGCACA TGGGCTGCTG ATAGTCAGCA AGGAGAGACT GGTCCCTCCA 
AGAGGCAACA AGACACAGTA TGAGGAGATA AGCATCCCTG TGGCCCTGCT AAGCCACAGG 
GACCTTCAAG ACATCTTCAG GCGCTTTGGC CACGAGGTAA TGGTAGCCCT GTATGCTCCG 
AGCGAGCCAG TGATGGACTA CAACATGGTC ATCATCTTCA TCATGGCCGT GGGCACCGTC 
GCCCTTGGTG GCTACTGGGC TGGCAGTCAT GATGTGAAGA AGTACATGAA GCATAAGCGA 
GACGACGTCC CTGAGAAGCA GGAGGATGAG GCGGTGGACG TGACGCCGGT CATGATCTGC 
GTGTTTGTTG TCATGTGCTG CTTCATGCTT GTGCTCCTCT ACTACTTCTA TGACCGCTTG 
GTCTACGTGA TCATTGGGAT CTTCTGCCTG GCCTCCTCTA CCGGCCTCTA CAGCTGCCTG 
GCACCCTGTG TGCGCAAGCT GCCCTTCTGC ACGTGCAGGG TCCCCGACAA CAACCTGCCG 
TACTTCCACA AGCGTCCACA GGCCCGCATG CTGCTGCTGG CCCTCTTCTG TGTCACTGTC 
TCCGTGGTGT GGGGTGTCTT CCGTAATGAG GACCAGTGGG CATGGGTCCT GCAGGACACC 
CTGGGCATTG CCTTCTGCCT GTACATGCTG AGGACCATTC GCCTGCCCAC CTTCAAGGCC 
TGCACACTGC TGCTGCTGGT GCTCTTCGTC TACGACATCT TCTTCGTCTT CATCACCCCC 
TACCTGACCA AGAGCGGCAA CAGCATCATG GTGGAGGTGG CCACTGGGCC CTCGAACTCA 
TCCACCCATG AGAAGCTGCC CATGGTGCTG AAGGTGCCCA GGCTGAACAC CTCGCCTCTC 
TCCCTGTGTG ACCGGCCCTT CTCCCTTCTG GGCTTTGGAG ACATCTTGGT GCCAGGGCTG 
CTGGTGGCCT ACTGCCACAG GTTTGATATC CAGGTGCAGT CCTCCAGGAT TTACTTTGTG 
GCCTGCACCA TTGCCTATGG CCTGGGCCTC CTGGTGACCT TCGTGGCTCT CGTCCTCATG 
CGACATGGCC AGCCTGCACT CCTCTACTTG GTCCCCTGCA CACTGCTGAC CAGCTGCACC 
GTGGCTCTGT GGCGCCGGGA GATGGGCGCC TTCTGGACGG GCAGCGGTTT TGCGGATGCA 
CCTCAGACCC CGTGGGCTGC ACCCCAGGGA CCTGTGCCTC CGAAGGATGT GGATGCCTCT 
CTCTCGGAGC AGCCTCGGGG TGAAGAGCTG GCCCAGAGCC CCCTGGCCAC TGAGGAGGCA 
GGAGCCACAG ACCCTGCCAA GGATCCTGAC AGCCCTGTGG CCGGTCCCCT CAGCCCCTCA 
AATGGGGACC AAGTCCAGCC TATACCTGTG GTGACCCCAG GGACCTCGGC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001014222.1
CDS	12..1745
Translation	MAAARLAASLLLLAAQVACEFGVLRVVPQSGGTRGRDYCILYNPQWAHLPHDLNKVSLLKLRDLSTTQLCSHLDVPVEDFTNQIALVARGNCTFYEKVRLAQGSGAHGLLIVSKERLVPPRGNKTQYEEISIPVALLSHRDLQDIFRRFGHEVMVALYAPSEPVMDYNMVIIFIMAVGTVALGGYWAGSHDVKKYMKHKRDDVPEKQEDEAVDVTPVMICVFVVMCCFMLVLLYYFYDRLVYVIIGIFCLASSTGLYSCLAPCVRKLPFCTCRVPDNNLPYFHKRPQARMLLLALFCVTVSVVWGVFRNEDQWAWVLQDTLGIAFCLYMLRTIRLPTFKACTLLLLVLFVYDIFFVFITPYLTKSGNSIMVEVATGPSNSSTHEKLPMVLKVPRLNTSPLSLCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSSRIYFVACTIAYGLGLLVTFVALVLMRHGQPALLYLVPCTLLTSCTVALWRREMGAFWTGSGFADAPQTPWAAPQGPVPPKDVDASLSEQPRGEELAQSPLATEEAGATDPAKDPDSPVAGPLSPSNGDQVQPIPVVTPGTSA

Target ORF information:

RefSeq Version	NM_001014200.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus signal peptide peptidase-like 2B (Sppl2b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001014200.1

ORF Insert Sequence:

ATGGCGGCGG CGCGGCTGGC CGCATCCCTG CTGCTACTCG CGGCCCAGGT GGCCTGTGAG 
TTCGGTGTAC TGCGAGTTGT GCCCCAAAGC GGTGGGACCC GGGGCAGGGA CTACTGCATC 
CTTTACAACC CACAGTGGGC CCACTTGCCT CATGACCTCA ACAAAGTGTC TCTTCTGAAG 
CTTCGAGACT TGAGCACGAC TCAGCTCTGT TCCCACCTCG ATGTTCCTGT AGAAGACTTC 
ACCAACCAGA TCGCACTGGT GGCTCGGGGC AACTGTACCT TCTATGAGAA AGTGCGGCTG 
GCCCAGGGCA GTGGGGCACA TGGGCTGCTG ATAGTCAGCA AGGAGAGACT GGTCCCTCCA 
AGAGGCAACA AGACACAGTA TGAGGAGATA AGCATCCCTG TGGCCCTGCT AAGCCACAGG 
GACCTTCAAG ACATCTTCAG GCGCTTTGGC CACGAGGTAA TGGTAGCCCT GTATGCTCCG 
AGCGAGCCAG TGATGGACTA CAACATGGTC ATCATCTTCA TCATGGCCGT GGGCACCGTC 
GCCCTTGGTG GCTACTGGGC TGGCAGTCAT GATGTGAAGA AGTACATGAA GCATAAGCGA 
GACGACGTCC CTGAGAAGCA GGAGGATGAG GCGGTGGACG TGACGCCGGT CATGATCTGC 
GTGTTTGTTG TCATGTGCTG CTTCATGCTT GTGCTCCTCT ACTACTTCTA TGACCGCTTG 
GTCTACGTGA TCATTGGGAT CTTCTGCCTG GCCTCCTCTA CCGGCCTCTA CAGCTGCCTG 
GCACCCTGTG TGCGCAAGCT GCCCTTCTGC ACGTGCAGGG TCCCCGACAA CAACCTGCCG 
TACTTCCACA AGCGTCCACA GGCCCGCATG CTGCTGCTGG CCCTCTTCTG TGTCACTGTC 
TCCGTGGTGT GGGGTGTCTT CCGTAATGAG GACCAGTGGG CATGGGTCCT GCAGGACACC 
CTGGGCATTG CCTTCTGCCT GTACATGCTG AGGACCATTC GCCTGCCCAC CTTCAAGGCC 
TGCACACTGC TGCTGCTGGT GCTCTTCGTC TACGACATCT TCTTCGTCTT CATCACCCCC 
TACCTGACCA AGAGCGGCAA CAGCATCATG GTGGAGGTGG CCACTGGGCC CTCGAACTCA 
TCCACCCATG AGAAGCTGCC CATGGTGCTG AAGGTGCCCA GGCTGAACAC CTCGCCTCTC 
TCCCTGTGTG ACCGGCCCTT CTCCCTTCTG GGCTTTGGAG ACATCTTGGT GCCAGGGCTG 
CTGGTGGCCT ACTGCCACAG GTTTGATATC CAGGTGCAGT CCTCCAGGAT TTACTTTGTG 
GCCTGCACCA TTGCCTATGG CCTGGGCCTC CTGGTGACCT TCGTGGCTCT CGTCCTCATG 
CGACATGGCC AGCCTGCACT CCTCTACTTG GTCCCCTGCA CACTGCTGAC CAGCTGCACC 
GTGGCTCTGT GGCGCCGGGA GATGGGCGCC TTCTGGACGG GCAGCGGTTT TGCGGATGCA 
CCTCAGACCC CGTGGGCTGC ACCCCAGGGA CCTGTGCCTC CGAAGGATGT GGATGCCTCT 
CTCTCGGAGC AGCCTCGGGG TGAAGAGCTG GCCCAGAGCC CCCTGGCCAC TGAGGAGGCA 
GGAGCCACAG ACCCTGCCAA GGATCCTGAC AGCCCTGTGG CCGGTCCCCT CAGCCCCTCA 
AATGGGGACC AAGTCCAGCC TATACCTGTG GTGACCCCAG GGACCTCGGC CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sppl2b ( XM_006240947.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006241009.1 Rattus norvegicus signal peptide peptidase-like 2B (Sppl2b), transcript variant X5, mRNA.

Price & Availability↑

CloneID	ORa29876
Clone ID Related Accession (Same CDS sequence)	XM_006240947.3
Accession Version	XM_006240947.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1740bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	signal peptide peptidase-like 2B isoform X5
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006240947.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGCGG CGCGGCTGGC CGCATCCCTG CTGCTACTCG CGGCCCAGGT GGCCTGTGAG 
TTCGGTGTAC TGCGAGTTGT GCCCCAAAGC GGTGGGACCC GGGGCAGGGA CTACTGCATC 
CTTTACAACC CACAGTGGGC CCACTTGCCT CATGACCTCA ACAAAGTGTC TCTTCTGAAG 
CTTCGAGACT TGAGCACGAC TCAGCTCTGT TCCCACCTCG ATGTTCCTGT AGAAGACTTC 
ACCAACCAGA TCGCACTGGT GGCTCGGGGC AACTGTACCT TCTATGAGAA AGTGCGGCTG 
GCCCAGGGCA GTGGGGCACA TGGGCTGCTG ATAGTCAGCA AGGAGAGACT GGTCCCTCCA 
AGAGGCAACA AGACACAGTA TGAGGAGATA AGCATCCCTG TGGCCCTGCT AAGCCACAGG 
GACCTTCAAG ACATCTTCAG GCGCTTTGGC CACGAGGTAA TGGTAGCCCT GTATGCTCCG 
AGCGAGCCAG TGATGGACTA CAACATGGTC ATCATCTTCA TCATGGCCGT GGGCACCGTC 
GCCCTTGGTG GCTACTGGGC TGGCAGTCAT GATGTGAAGA AAAGGTACAT GAAGCATAAG 
CGAGACGACG TCCCTGAGAA GCAGGAGGAT GAGGCGGTGG ACGTGACGCC GGTCATGATC 
TGCGTGTTTG TTGTCATGTG CTGCTTCATG CTTGTGCTCC TCTACTACTT CTATGACCGC 
TTGGTCTACG TGATCATTGG GATCTTCTGC CTGGCCTCCT CTACCGGCCT CTACAGCTGC 
CTGGCACCCT GTGTGCGCAA GCTGCCCTTC TGCACGTGCA GGGTCCCCGA CAACAACCTG 
CCGTACTTCC ACAAGCGTCC ACAGGCCCGC ATGCTGCTGC TGGCCCTCTT CTGTGTCACT 
GTCTCCGTGG TGTGGGGTGT CTTCCGTAAT GAGGACCAGT GGGCATGGGT CCTGCAGGAC 
ACCCTGGGCA TTGCCTTCTG CCTGTACATG CTGAGGACCA TTCGCCTGCC CACCTTCAAG 
GCCTGCACAC TGCTGCTGCT GGTGCTCTTC GTCTACGACA TCTTCTTCGT CTTCATCACC 
CCCTACCTGA CCAAGAGCGG CAACAGCATC ATGGTGGAGG TGGCCACTGG GCCCTCGAAC 
TCATCCACCC ATGAGAAGCT GCCCATGGTG CTGAAGGTGC CCAGGCTGAA CACCTCGCCT 
CTCTCCCTGT GTGACCGGCC CTTCTCCCTT CTGGGCTTTG GAGACATCTT GGTGCCAGGG 
CTGCTGGTGG CCTACTGCCA CAGGTTTGAT ATCCAGGTGC AGTCCTCCAG GATTTACTTT 
GTGGCCTGCA CCATTGCCTA TGGCCTGGGC CTCCTGGTGA CCTTCGTGGC TCTCGTCCTC 
ATGCGACATG GCCAGCCTGC ACTCCTCTAC TTGGTCCCCT GCACACTGCT GACCAGCTGC 
ACCGTGGCTC TGTGGCGCCG GGAGATGGGC GCCTTCTGGA CGGGCAGCGG TTTTGCGAAG 
GATGCACCTC AGACCCCGTG GGCTGCACCC CAGGGACCTG TGCCTCCGAA GGATGTGGAT 
GCCTCTCTCT CGGAGCAGCC TCGGGGTGAA GAGCTGGCCC AGAGCCCCCT GGCCACTGAG 
GAGGCAGGAG CCACAGACCC TGCCAAGGAT CCTGACAGCC CTGTGGCCGG TCCCCTCAGC 
CCCTCAAATG GGGACCAAGT CCAGCCTATA CCTGTGGTGA CCCCAGGGAC CTCGGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006241009.1
CDS	81..1820
Translation	MAAARLAASLLLLAAQVACEFGVLRVVPQSGGTRGRDYCILYNPQWAHLPHDLNKVSLLKLRDLSTTQLCSHLDVPVEDFTNQIALVARGNCTFYEKVRLAQGSGAHGLLIVSKERLVPPRGNKTQYEEISIPVALLSHRDLQDIFRRFGHEVMVALYAPSEPVMDYNMVIIFIMAVGTVALGGYWAGSHDVKKRYMKHKRDDVPEKQEDEAVDVTPVMICVFVVMCCFMLVLLYYFYDRLVYVIIGIFCLASSTGLYSCLAPCVRKLPFCTCRVPDNNLPYFHKRPQARMLLLALFCVTVSVVWGVFRNEDQWAWVLQDTLGIAFCLYMLRTIRLPTFKACTLLLLVLFVYDIFFVFITPYLTKSGNSIMVEVATGPSNSSTHEKLPMVLKVPRLNTSPLSLCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSSRIYFVACTIAYGLGLLVTFVALVLMRHGQPALLYLVPCTLLTSCTVALWRREMGAFWTGSGFAKDAPQTPWAAPQGPVPPKDVDASLSEQPRGEELAQSPLATEEAGATDPAKDPDSPVAGPLSPSNGDQVQPIPVVTPGTSA

Target ORF information:

RefSeq Version	XM_006240947.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus signal peptide peptidase-like 2B (Sppl2b), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006240947.3

ORF Insert Sequence:

ATGGCGGCGG CGCGGCTGGC CGCATCCCTG CTGCTACTCG CGGCCCAGGT GGCCTGTGAG 
TTCGGTGTAC TGCGAGTTGT GCCCCAAAGC GGTGGGACCC GGGGCAGGGA CTACTGCATC 
CTTTACAACC CACAGTGGGC CCACTTGCCT CATGACCTCA ACAAAGTGTC TCTTCTGAAG 
CTTCGAGACT TGAGCACGAC TCAGCTCTGT TCCCACCTCG ATGTTCCTGT AGAAGACTTC 
ACCAACCAGA TCGCACTGGT GGCTCGGGGC AACTGTACCT TCTATGAGAA AGTGCGGCTG 
GCCCAGGGCA GTGGGGCACA TGGGCTGCTG ATAGTCAGCA AGGAGAGACT GGTCCCTCCA 
AGAGGCAACA AGACACAGTA TGAGGAGATA AGCATCCCTG TGGCCCTGCT AAGCCACAGG 
GACCTTCAAG ACATCTTCAG GCGCTTTGGC CACGAGGTAA TGGTAGCCCT GTATGCTCCG 
AGCGAGCCAG TGATGGACTA CAACATGGTC ATCATCTTCA TCATGGCCGT GGGCACCGTC 
GCCCTTGGTG GCTACTGGGC TGGCAGTCAT GATGTGAAGA AAAGGTACAT GAAGCATAAG 
CGAGACGACG TCCCTGAGAA GCAGGAGGAT GAGGCGGTGG ACGTGACGCC GGTCATGATC 
TGCGTGTTTG TTGTCATGTG CTGCTTCATG CTTGTGCTCC TCTACTACTT CTATGACCGC 
TTGGTCTACG TGATCATTGG GATCTTCTGC CTGGCCTCCT CTACCGGCCT CTACAGCTGC 
CTGGCACCCT GTGTGCGCAA GCTGCCCTTC TGCACGTGCA GGGTCCCCGA CAACAACCTG 
CCGTACTTCC ACAAGCGTCC ACAGGCCCGC ATGCTGCTGC TGGCCCTCTT CTGTGTCACT 
GTCTCCGTGG TGTGGGGTGT CTTCCGTAAT GAGGACCAGT GGGCATGGGT CCTGCAGGAC 
ACCCTGGGCA TTGCCTTCTG CCTGTACATG CTGAGGACCA TTCGCCTGCC CACCTTCAAG 
GCCTGCACAC TGCTGCTGCT GGTGCTCTTC GTCTACGACA TCTTCTTCGT CTTCATCACC 
CCCTACCTGA CCAAGAGCGG CAACAGCATC ATGGTGGAGG TGGCCACTGG GCCCTCGAAC 
TCATCCACCC ATGAGAAGCT GCCCATGGTG CTGAAGGTGC CCAGGCTGAA CACCTCGCCT 
CTCTCCCTGT GTGACCGGCC CTTCTCCCTT CTGGGCTTTG GAGACATCTT GGTGCCAGGG 
CTGCTGGTGG CCTACTGCCA CAGGTTTGAT ATCCAGGTGC AGTCCTCCAG GATTTACTTT 
GTGGCCTGCA CCATTGCCTA TGGCCTGGGC CTCCTGGTGA CCTTCGTGGC TCTCGTCCTC 
ATGCGACATG GCCAGCCTGC ACTCCTCTAC TTGGTCCCCT GCACACTGCT GACCAGCTGC 
ACCGTGGCTC TGTGGCGCCG GGAGATGGGC GCCTTCTGGA CGGGCAGCGG TTTTGCGAAG 
GATGCACCTC AGACCCCGTG GGCTGCACCC CAGGGACCTG TGCCTCCGAA GGATGTGGAT 
GCCTCTCTCT CGGAGCAGCC TCGGGGTGAA GAGCTGGCCC AGAGCCCCCT GGCCACTGAG 
GAGGCAGGAG CCACAGACCC TGCCAAGGAT CCTGACAGCC CTGTGGCCGG TCCCCTCAGC 
CCCTCAAATG GGGACCAAGT CCAGCCTATA CCTGTGGTGA CCCCAGGGAC CTCGGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sppl2b ( XM_006240948.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006241010.1 Rattus norvegicus signal peptide peptidase-like 2B (Sppl2b), transcript variant X6, mRNA.

Price & Availability↑

CloneID	ORa29877
Clone ID Related Accession (Same CDS sequence)	XM_006240948.3
Accession Version	XM_006240948.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1737bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	signal peptide peptidase-like 2B isoform X6
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006240948.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGCGG CGCGGCTGGC CGCATCCCTG CTGCTACTCG CGGCCCAGGT GGCCTGTGAG 
TTCGGTGTAC TGCGAGTTGT GCCCCAAAGC GGTGGGACCC GGGGCAGGGA CTACTGCATC 
CTTTACAACC CACAGTGGGC CCACTTGCCT CATGACCTCA ACAAAGTGTC TCTTCTGAAG 
CTTCGAGACT TGAGCACGAC TCAGCTCTGT TCCCACCTCG ATGTTCCTGT AGAAGACTTC 
ACCAACCAGA TCGCACTGGT GGCTCGGGGC AACTGTACCT TCTATGAGAA AGTGCGGCTG 
GCCCAGGGCA GTGGGGCACA TGGGCTGCTG ATAGTCAGCA AGGAGAGACT GGTCCCTCCA 
AGAGGCAACA AGACACAGTA TGAGGAGATA AGCATCCCTG TGGCCCTGCT AAGCCACAGG 
GACCTTCAAG ACATCTTCAG GCGCTTTGGC CACGAGGTAA TGGTAGCCCT GTATGCTCCG 
AGCGAGCCAG TGATGGACTA CAACATGGTC ATCATCTTCA TCATGGCCGT GGGCACCGTC 
GCCCTTGGTG GCTACTGGGC TGGCAGTCAT GATGTGAAGA AGTACATGAA GCATAAGCGA 
GACGACGTCC CTGAGAAGCA GGAGGATGAG GCGGTGGACG TGACGCCGGT CATGATCTGC 
GTGTTTGTTG TCATGTGCTG CTTCATGCTT GTGCTCCTCT ACTACTTCTA TGACCGCTTG 
GTCTACGTGA TCATTGGGAT CTTCTGCCTG GCCTCCTCTA CCGGCCTCTA CAGCTGCCTG 
GCACCCTGTG TGCGCAAGCT GCCCTTCTGC ACGTGCAGGG TCCCCGACAA CAACCTGCCG 
TACTTCCACA AGCGTCCACA GGCCCGCATG CTGCTGCTGG CCCTCTTCTG TGTCACTGTC 
TCCGTGGTGT GGGGTGTCTT CCGTAATGAG GACCAGTGGG CATGGGTCCT GCAGGACACC 
CTGGGCATTG CCTTCTGCCT GTACATGCTG AGGACCATTC GCCTGCCCAC CTTCAAGGCC 
TGCACACTGC TGCTGCTGGT GCTCTTCGTC TACGACATCT TCTTCGTCTT CATCACCCCC 
TACCTGACCA AGAGCGGCAA CAGCATCATG GTGGAGGTGG CCACTGGGCC CTCGAACTCA 
TCCACCCATG AGAAGCTGCC CATGGTGCTG AAGGTGCCCA GGCTGAACAC CTCGCCTCTC 
TCCCTGTGTG ACCGGCCCTT CTCCCTTCTG GGCTTTGGAG ACATCTTGGT GCCAGGGCTG 
CTGGTGGCCT ACTGCCACAG GTTTGATATC CAGGTGCAGT CCTCCAGGAT TTACTTTGTG 
GCCTGCACCA TTGCCTATGG CCTGGGCCTC CTGGTGACCT TCGTGGCTCT CGTCCTCATG 
CGACATGGCC AGCCTGCACT CCTCTACTTG GTCCCCTGCA CACTGCTGAC CAGCTGCACC 
GTGGCTCTGT GGCGCCGGGA GATGGGCGCC TTCTGGACGG GCAGCGGTTT TGCGAAGGAT 
GCACCTCAGA CCCCGTGGGC TGCACCCCAG GGACCTGTGC CTCCGAAGGA TGTGGATGCC 
TCTCTCTCGG AGCAGCCTCG GGGTGAAGAG CTGGCCCAGA GCCCCCTGGC CACTGAGGAG 
GCAGGAGCCA CAGACCCTGC CAAGGATCCT GACAGCCCTG TGGCCGGTCC CCTCAGCCCC 
TCAAATGGGG ACCAAGTCCA GCCTATACCT GTGGTGACCC CAGGGACCTC GGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006241010.1
CDS	80..1816
Translation	MAAARLAASLLLLAAQVACEFGVLRVVPQSGGTRGRDYCILYNPQWAHLPHDLNKVSLLKLRDLSTTQLCSHLDVPVEDFTNQIALVARGNCTFYEKVRLAQGSGAHGLLIVSKERLVPPRGNKTQYEEISIPVALLSHRDLQDIFRRFGHEVMVALYAPSEPVMDYNMVIIFIMAVGTVALGGYWAGSHDVKKYMKHKRDDVPEKQEDEAVDVTPVMICVFVVMCCFMLVLLYYFYDRLVYVIIGIFCLASSTGLYSCLAPCVRKLPFCTCRVPDNNLPYFHKRPQARMLLLALFCVTVSVVWGVFRNEDQWAWVLQDTLGIAFCLYMLRTIRLPTFKACTLLLLVLFVYDIFFVFITPYLTKSGNSIMVEVATGPSNSSTHEKLPMVLKVPRLNTSPLSLCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSSRIYFVACTIAYGLGLLVTFVALVLMRHGQPALLYLVPCTLLTSCTVALWRREMGAFWTGSGFAKDAPQTPWAAPQGPVPPKDVDASLSEQPRGEELAQSPLATEEAGATDPAKDPDSPVAGPLSPSNGDQVQPIPVVTPGTSA

Target ORF information:

RefSeq Version	XM_006240948.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus signal peptide peptidase-like 2B (Sppl2b), transcript variant X6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006240948.3

ORF Insert Sequence:

ATGGCGGCGG CGCGGCTGGC CGCATCCCTG CTGCTACTCG CGGCCCAGGT GGCCTGTGAG 
TTCGGTGTAC TGCGAGTTGT GCCCCAAAGC GGTGGGACCC GGGGCAGGGA CTACTGCATC 
CTTTACAACC CACAGTGGGC CCACTTGCCT CATGACCTCA ACAAAGTGTC TCTTCTGAAG 
CTTCGAGACT TGAGCACGAC TCAGCTCTGT TCCCACCTCG ATGTTCCTGT AGAAGACTTC 
ACCAACCAGA TCGCACTGGT GGCTCGGGGC AACTGTACCT TCTATGAGAA AGTGCGGCTG 
GCCCAGGGCA GTGGGGCACA TGGGCTGCTG ATAGTCAGCA AGGAGAGACT GGTCCCTCCA 
AGAGGCAACA AGACACAGTA TGAGGAGATA AGCATCCCTG TGGCCCTGCT AAGCCACAGG 
GACCTTCAAG ACATCTTCAG GCGCTTTGGC CACGAGGTAA TGGTAGCCCT GTATGCTCCG 
AGCGAGCCAG TGATGGACTA CAACATGGTC ATCATCTTCA TCATGGCCGT GGGCACCGTC 
GCCCTTGGTG GCTACTGGGC TGGCAGTCAT GATGTGAAGA AGTACATGAA GCATAAGCGA 
GACGACGTCC CTGAGAAGCA GGAGGATGAG GCGGTGGACG TGACGCCGGT CATGATCTGC 
GTGTTTGTTG TCATGTGCTG CTTCATGCTT GTGCTCCTCT ACTACTTCTA TGACCGCTTG 
GTCTACGTGA TCATTGGGAT CTTCTGCCTG GCCTCCTCTA CCGGCCTCTA CAGCTGCCTG 
GCACCCTGTG TGCGCAAGCT GCCCTTCTGC ACGTGCAGGG TCCCCGACAA CAACCTGCCG 
TACTTCCACA AGCGTCCACA GGCCCGCATG CTGCTGCTGG CCCTCTTCTG TGTCACTGTC 
TCCGTGGTGT GGGGTGTCTT CCGTAATGAG GACCAGTGGG CATGGGTCCT GCAGGACACC 
CTGGGCATTG CCTTCTGCCT GTACATGCTG AGGACCATTC GCCTGCCCAC CTTCAAGGCC 
TGCACACTGC TGCTGCTGGT GCTCTTCGTC TACGACATCT TCTTCGTCTT CATCACCCCC 
TACCTGACCA AGAGCGGCAA CAGCATCATG GTGGAGGTGG CCACTGGGCC CTCGAACTCA 
TCCACCCATG AGAAGCTGCC CATGGTGCTG AAGGTGCCCA GGCTGAACAC CTCGCCTCTC 
TCCCTGTGTG ACCGGCCCTT CTCCCTTCTG GGCTTTGGAG ACATCTTGGT GCCAGGGCTG 
CTGGTGGCCT ACTGCCACAG GTTTGATATC CAGGTGCAGT CCTCCAGGAT TTACTTTGTG 
GCCTGCACCA TTGCCTATGG CCTGGGCCTC CTGGTGACCT TCGTGGCTCT CGTCCTCATG 
CGACATGGCC AGCCTGCACT CCTCTACTTG GTCCCCTGCA CACTGCTGAC CAGCTGCACC 
GTGGCTCTGT GGCGCCGGGA GATGGGCGCC TTCTGGACGG GCAGCGGTTT TGCGAAGGAT 
GCACCTCAGA CCCCGTGGGC TGCACCCCAG GGACCTGTGC CTCCGAAGGA TGTGGATGCC 
TCTCTCTCGG AGCAGCCTCG GGGTGAAGAG CTGGCCCAGA GCCCCCTGGC CACTGAGGAG 
GCAGGAGCCA CAGACCCTGC CAAGGATCCT GACAGCCCTG TGGCCGGTCC CCTCAGCCCC 
TCAAATGGGG ACCAAGTCCA GCCTATACCT GTGGTGACCC CAGGGACCTC GGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sppl2b ( XM_008765111.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008763333.1 Rattus norvegicus signal peptide peptidase-like 2B (Sppl2b), transcript variant X1, mRNA.

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CloneID	ORa48366
Clone ID Related Accession (Same CDS sequence)	XM_008765111.2
Accession Version	XM_008765111.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1899bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	signal peptide peptidase-like 2B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008765111.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGCGG CGCGGCTGGC CGCATCCCTG CTGCTACTCG CGGCCCAGGT GGCCTGTGAG 
TTCGGTGTAC TGCGAGTTGT GCCCCAAAGC GGTGGGACCC GGGGCAGGGA CTACTGCATC 
CTTTACAACC CACAGTGGGC CCACTTGCCT CATGACCTCA ACAAAGTGTC TCTTCTGAAG 
CTTCGAGACT TGAGCACGAC TCAGCTCTGT TCCCACCTCG ATGTTCCTGT AGAAGACTTC 
ACCAACCAGA TCGCACTGGT GGCTCGGGGC AACTGTACCT TCTATGAGAA AGTGCGGCTG 
GCCCAGGGCA GTGGGGCACA TGGGCTGCTG ATAGTCAGCA AGGAGAGACT GGTCCCTCCA 
AGAGGCAACA AGACACAGTA TGAGGAGATA AGCATCCCTG TGGCCCTGCT AAGCCACAGG 
GACCTTCAAG ACATCTTCAG GCGCTTTGGC CACGAGGTAA TGGTAGCCCT GTATGCTCCG 
AGCGAGCCAG TGATGGACTA CAACATGGTC ATCATCTTCA TCATGGCCGT GGGCACCGTC 
GCCCTTGGTG GCTACTGGGC TGGCAGTCAT GATGTGAAGA AAAGGTACAT GAAGCATAAG 
CGAGACGACG TCCCTGAGAA GCAGGAGGAT GAGGCGGTGG ACGTGACGCC GGTCATGATC 
TGCGTGTTTG TTGTCATGTG CTGCTTCATG CTTGTGCTCC TCTACTACTT CTATGACCGC 
TTGGTCTACG TGATCATTGG GATCTTCTGC CTGGCCTCCT CTACCGGCCT CTACAGCTGC 
CTGGCACCCT GTGTGCGCAA GCTGCCCTTC TGCACGTGCA GGGTCCCCGA CAACAACCTG 
CCGTACTTCC ACAAGCGTCC ACAGGCCCGC ATGCTGCTGC TGGCCCTCTT CTGTGTCACT 
GTCTCCGTGG TGTGGGGTGT CTTCCGTAAT GAGGACCAGT GGGCATGGGT CCTGCAGGAC 
ACCCTGGGCA TTGCCTTCTG CCTGTACATG CTGAGGACCA TTCGCCTGCC CACCTTCAAG 
GTGAGGGCTG CCATGGCAGG GCAGGTCAAT TCCTGGTGGG GGGCTGAGGG CCTGGGCGCA 
CAGGTCTCGA GGGCAGTGCT GGCTCCCACA GGCCTGCACA CTGCTGCTGC TGGTGCTCTT 
CGTCTACGAC ATCTTCTTCG TCTTCATCAC CCCCTACCTG ACCAAGGTAG GTCCCCTCTA 
CCCTCCCAGC TGCCCGCCCC TCCCCTGCCC TGGCTGACAA CCTGTCTTGT GCAGAGCGGC 
AACAGCATCA TGGTGGAGGT GGCCACTGGG CCCTCGAACT CATCCACCCA TGAGAAGCTG 
CCCATGGTGC TGAAGGTGCC CAGGCTGAAC ACCTCGCCTC TCTCCCTGTG TGACCGGCCC 
TTCTCCCTTC TGGGCTTTGG AGACATCTTG GTGCCAGGGC TGCTGGTGGC CTACTGCCAC 
AGGTTTGATA TCCAGGTGCA GTCCTCCAGG ATTTACTTTG TGGCCTGCAC CATTGCCTAT 
GGCCTGGGCC TCCTGGTGAC CTTCGTGGCT CTCGTCCTCA TGCGACATGG CCAGCCTGCA 
CTCCTCTACT TGGTCCCCTG CACACTGCTG ACCAGCTGCA CCGTGGCTCT GTGGCGCCGG 
GAGATGGGCG CCTTCTGGAC GGGCAGCGGT TTTGCGAAGG ATGCACCTCA GACCCCGTGG 
GCTGCACCCC AGGGACCTGT GCCTCCGAAG GATGTGGATG CCTCTCTCTC GGAGCAGCCT 
CGGGGTGAAG AGCTGGCCCA GAGCCCCCTG GCCACTGAGG AGGCAGGAGC CACAGACCCT 
GCCAAGGATC CTGACAGCCC TGTGGCCGGT CCCCTCAGCC CCTCAAATGG GGACCAAGTC 
CAGCCTATAC CTGTGGTGAC CCCAGGGACC TCGGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008763333.1
CDS	83..1981
Translation	MAAARLAASLLLLAAQVACEFGVLRVVPQSGGTRGRDYCILYNPQWAHLPHDLNKVSLLKLRDLSTTQLCSHLDVPVEDFTNQIALVARGNCTFYEKVRLAQGSGAHGLLIVSKERLVPPRGNKTQYEEISIPVALLSHRDLQDIFRRFGHEVMVALYAPSEPVMDYNMVIIFIMAVGTVALGGYWAGSHDVKKRYMKHKRDDVPEKQEDEAVDVTPVMICVFVVMCCFMLVLLYYFYDRLVYVIIGIFCLASSTGLYSCLAPCVRKLPFCTCRVPDNNLPYFHKRPQARMLLLALFCVTVSVVWGVFRNEDQWAWVLQDTLGIAFCLYMLRTIRLPTFKVRAAMAGQVNSWWGAEGLGAQVSRAVLAPTGLHTAAAGALRLRHLLRLHHPLPDQGRSPLPSQLPAPPLPWLTTCLVQSGNSIMVEVATGPSNSSTHEKLPMVLKVPRLNTSPLSLCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSSRIYFVACTIAYGLGLLVTFVALVLMRHGQPALLYLVPCTLLTSCTVALWRREMGAFWTGSGFAKDAPQTPWAAPQGPVPPKDVDASLSEQPRGEELAQSPLATEEAGATDPAKDPDSPVAGPLSPSNGDQVQPIPVVTPGTSA

Target ORF information:

RefSeq Version	XM_008765111.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus signal peptide peptidase-like 2B (Sppl2b), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008765111.2

ORF Insert Sequence:

ATGGCGGCGG CGCGGCTGGC CGCATCCCTG CTGCTACTCG CGGCCCAGGT GGCCTGTGAG 
TTCGGTGTAC TGCGAGTTGT GCCCCAAAGC GGTGGGACCC GGGGCAGGGA CTACTGCATC 
CTTTACAACC CACAGTGGGC CCACTTGCCT CATGACCTCA ACAAAGTGTC TCTTCTGAAG 
CTTCGAGACT TGAGCACGAC TCAGCTCTGT TCCCACCTCG ATGTTCCTGT AGAAGACTTC 
ACCAACCAGA TCGCACTGGT GGCTCGGGGC AACTGTACCT TCTATGAGAA AGTGCGGCTG 
GCCCAGGGCA GTGGGGCACA TGGGCTGCTG ATAGTCAGCA AGGAGAGACT GGTCCCTCCA 
AGAGGCAACA AGACACAGTA TGAGGAGATA AGCATCCCTG TGGCCCTGCT AAGCCACAGG 
GACCTTCAAG ACATCTTCAG GCGCTTTGGC CACGAGGTAA TGGTAGCCCT GTATGCTCCG 
AGCGAGCCAG TGATGGACTA CAACATGGTC ATCATCTTCA TCATGGCCGT GGGCACCGTC 
GCCCTTGGTG GCTACTGGGC TGGCAGTCAT GATGTGAAGA AAAGGTACAT GAAGCATAAG 
CGAGACGACG TCCCTGAGAA GCAGGAGGAT GAGGCGGTGG ACGTGACGCC GGTCATGATC 
TGCGTGTTTG TTGTCATGTG CTGCTTCATG CTTGTGCTCC TCTACTACTT CTATGACCGC 
TTGGTCTACG TGATCATTGG GATCTTCTGC CTGGCCTCCT CTACCGGCCT CTACAGCTGC 
CTGGCACCCT GTGTGCGCAA GCTGCCCTTC TGCACGTGCA GGGTCCCCGA CAACAACCTG 
CCGTACTTCC ACAAGCGTCC ACAGGCCCGC ATGCTGCTGC TGGCCCTCTT CTGTGTCACT 
GTCTCCGTGG TGTGGGGTGT CTTCCGTAAT GAGGACCAGT GGGCATGGGT CCTGCAGGAC 
ACCCTGGGCA TTGCCTTCTG CCTGTACATG CTGAGGACCA TTCGCCTGCC CACCTTCAAG 
GTGAGGGCTG CCATGGCAGG GCAGGTCAAT TCCTGGTGGG GGGCTGAGGG CCTGGGCGCA 
CAGGTCTCGA GGGCAGTGCT GGCTCCCACA GGCCTGCACA CTGCTGCTGC TGGTGCTCTT 
CGTCTACGAC ATCTTCTTCG TCTTCATCAC CCCCTACCTG ACCAAGGTAG GTCCCCTCTA 
CCCTCCCAGC TGCCCGCCCC TCCCCTGCCC TGGCTGACAA CCTGTCTTGT GCAGAGCGGC 
AACAGCATCA TGGTGGAGGT GGCCACTGGG CCCTCGAACT CATCCACCCA TGAGAAGCTG 
CCCATGGTGC TGAAGGTGCC CAGGCTGAAC ACCTCGCCTC TCTCCCTGTG TGACCGGCCC 
TTCTCCCTTC TGGGCTTTGG AGACATCTTG GTGCCAGGGC TGCTGGTGGC CTACTGCCAC 
AGGTTTGATA TCCAGGTGCA GTCCTCCAGG ATTTACTTTG TGGCCTGCAC CATTGCCTAT 
GGCCTGGGCC TCCTGGTGAC CTTCGTGGCT CTCGTCCTCA TGCGACATGG CCAGCCTGCA 
CTCCTCTACT TGGTCCCCTG CACACTGCTG ACCAGCTGCA CCGTGGCTCT GTGGCGCCGG 
GAGATGGGCG CCTTCTGGAC GGGCAGCGGT TTTGCGAAGG ATGCACCTCA GACCCCGTGG 
GCTGCACCCC AGGGACCTGT GCCTCCGAAG GATGTGGATG CCTCTCTCTC GGAGCAGCCT 
CGGGGTGAAG AGCTGGCCCA GAGCCCCCTG GCCACTGAGG AGGCAGGAGC CACAGACCCT 
GCCAAGGATC CTGACAGCCC TGTGGCCGGT CCCCTCAGCC CCTCAAATGG GGACCAAGTC 
CAGCCTATAC CTGTGGTGAC CCCAGGGACC TCGGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sppl2b ( XM_008765112.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008763334.1 Rattus norvegicus signal peptide peptidase-like 2B (Sppl2b), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa48367
Clone ID Related Accession (Same CDS sequence)	XM_008765112.2
Accession Version	XM_008765112.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1896bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	signal peptide peptidase-like 2B isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008765112.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGCGG CGCGGCTGGC CGCATCCCTG CTGCTACTCG CGGCCCAGGT GGCCTGTGAG 
TTCGGTGTAC TGCGAGTTGT GCCCCAAAGC GGTGGGACCC GGGGCAGGGA CTACTGCATC 
CTTTACAACC CACAGTGGGC CCACTTGCCT CATGACCTCA ACAAAGTGTC TCTTCTGAAG 
CTTCGAGACT TGAGCACGAC TCAGCTCTGT TCCCACCTCG ATGTTCCTGT AGAAGACTTC 
ACCAACCAGA TCGCACTGGT GGCTCGGGGC AACTGTACCT TCTATGAGAA AGTGCGGCTG 
GCCCAGGGCA GTGGGGCACA TGGGCTGCTG ATAGTCAGCA AGGAGAGACT GGTCCCTCCA 
AGAGGCAACA AGACACAGTA TGAGGAGATA AGCATCCCTG TGGCCCTGCT AAGCCACAGG 
GACCTTCAAG ACATCTTCAG GCGCTTTGGC CACGAGGTAA TGGTAGCCCT GTATGCTCCG 
AGCGAGCCAG TGATGGACTA CAACATGGTC ATCATCTTCA TCATGGCCGT GGGCACCGTC 
GCCCTTGGTG GCTACTGGGC TGGCAGTCAT GATGTGAAGA AGTACATGAA GCATAAGCGA 
GACGACGTCC CTGAGAAGCA GGAGGATGAG GCGGTGGACG TGACGCCGGT CATGATCTGC 
GTGTTTGTTG TCATGTGCTG CTTCATGCTT GTGCTCCTCT ACTACTTCTA TGACCGCTTG 
GTCTACGTGA TCATTGGGAT CTTCTGCCTG GCCTCCTCTA CCGGCCTCTA CAGCTGCCTG 
GCACCCTGTG TGCGCAAGCT GCCCTTCTGC ACGTGCAGGG TCCCCGACAA CAACCTGCCG 
TACTTCCACA AGCGTCCACA GGCCCGCATG CTGCTGCTGG CCCTCTTCTG TGTCACTGTC 
TCCGTGGTGT GGGGTGTCTT CCGTAATGAG GACCAGTGGG CATGGGTCCT GCAGGACACC 
CTGGGCATTG CCTTCTGCCT GTACATGCTG AGGACCATTC GCCTGCCCAC CTTCAAGGTG 
AGGGCTGCCA TGGCAGGGCA GGTCAATTCC TGGTGGGGGG CTGAGGGCCT GGGCGCACAG 
GTCTCGAGGG CAGTGCTGGC TCCCACAGGC CTGCACACTG CTGCTGCTGG TGCTCTTCGT 
CTACGACATC TTCTTCGTCT TCATCACCCC CTACCTGACC AAGGTAGGTC CCCTCTACCC 
TCCCAGCTGC CCGCCCCTCC CCTGCCCTGG CTGACAACCT GTCTTGTGCA GAGCGGCAAC 
AGCATCATGG TGGAGGTGGC CACTGGGCCC TCGAACTCAT CCACCCATGA GAAGCTGCCC 
ATGGTGCTGA AGGTGCCCAG GCTGAACACC TCGCCTCTCT CCCTGTGTGA CCGGCCCTTC 
TCCCTTCTGG GCTTTGGAGA CATCTTGGTG CCAGGGCTGC TGGTGGCCTA CTGCCACAGG 
TTTGATATCC AGGTGCAGTC CTCCAGGATT TACTTTGTGG CCTGCACCAT TGCCTATGGC 
CTGGGCCTCC TGGTGACCTT CGTGGCTCTC GTCCTCATGC GACATGGCCA GCCTGCACTC 
CTCTACTTGG TCCCCTGCAC ACTGCTGACC AGCTGCACCG TGGCTCTGTG GCGCCGGGAG 
ATGGGCGCCT TCTGGACGGG CAGCGGTTTT GCGAAGGATG CACCTCAGAC CCCGTGGGCT 
GCACCCCAGG GACCTGTGCC TCCGAAGGAT GTGGATGCCT CTCTCTCGGA GCAGCCTCGG 
GGTGAAGAGC TGGCCCAGAG CCCCCTGGCC ACTGAGGAGG CAGGAGCCAC AGACCCTGCC 
AAGGATCCTG ACAGCCCTGT GGCCGGTCCC CTCAGCCCCT CAAATGGGGA CCAAGTCCAG 
CCTATACCTG TGGTGACCCC AGGGACCTCG GCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008763334.1
CDS	83..1978
Translation	MAAARLAASLLLLAAQVACEFGVLRVVPQSGGTRGRDYCILYNPQWAHLPHDLNKVSLLKLRDLSTTQLCSHLDVPVEDFTNQIALVARGNCTFYEKVRLAQGSGAHGLLIVSKERLVPPRGNKTQYEEISIPVALLSHRDLQDIFRRFGHEVMVALYAPSEPVMDYNMVIIFIMAVGTVALGGYWAGSHDVKKYMKHKRDDVPEKQEDEAVDVTPVMICVFVVMCCFMLVLLYYFYDRLVYVIIGIFCLASSTGLYSCLAPCVRKLPFCTCRVPDNNLPYFHKRPQARMLLLALFCVTVSVVWGVFRNEDQWAWVLQDTLGIAFCLYMLRTIRLPTFKVRAAMAGQVNSWWGAEGLGAQVSRAVLAPTGLHTAAAGALRLRHLLRLHHPLPDQGRSPLPSQLPAPPLPWLTTCLVQSGNSIMVEVATGPSNSSTHEKLPMVLKVPRLNTSPLSLCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSSRIYFVACTIAYGLGLLVTFVALVLMRHGQPALLYLVPCTLLTSCTVALWRREMGAFWTGSGFAKDAPQTPWAAPQGPVPPKDVDASLSEQPRGEELAQSPLATEEAGATDPAKDPDSPVAGPLSPSNGDQVQPIPVVTPGTSA

Target ORF information:

RefSeq Version	XM_008765112.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus signal peptide peptidase-like 2B (Sppl2b), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008765112.2

ORF Insert Sequence:

ATGGCGGCGG CGCGGCTGGC CGCATCCCTG CTGCTACTCG CGGCCCAGGT GGCCTGTGAG 
TTCGGTGTAC TGCGAGTTGT GCCCCAAAGC GGTGGGACCC GGGGCAGGGA CTACTGCATC 
CTTTACAACC CACAGTGGGC CCACTTGCCT CATGACCTCA ACAAAGTGTC TCTTCTGAAG 
CTTCGAGACT TGAGCACGAC TCAGCTCTGT TCCCACCTCG ATGTTCCTGT AGAAGACTTC 
ACCAACCAGA TCGCACTGGT GGCTCGGGGC AACTGTACCT TCTATGAGAA AGTGCGGCTG 
GCCCAGGGCA GTGGGGCACA TGGGCTGCTG ATAGTCAGCA AGGAGAGACT GGTCCCTCCA 
AGAGGCAACA AGACACAGTA TGAGGAGATA AGCATCCCTG TGGCCCTGCT AAGCCACAGG 
GACCTTCAAG ACATCTTCAG GCGCTTTGGC CACGAGGTAA TGGTAGCCCT GTATGCTCCG 
AGCGAGCCAG TGATGGACTA CAACATGGTC ATCATCTTCA TCATGGCCGT GGGCACCGTC 
GCCCTTGGTG GCTACTGGGC TGGCAGTCAT GATGTGAAGA AGTACATGAA GCATAAGCGA 
GACGACGTCC CTGAGAAGCA GGAGGATGAG GCGGTGGACG TGACGCCGGT CATGATCTGC 
GTGTTTGTTG TCATGTGCTG CTTCATGCTT GTGCTCCTCT ACTACTTCTA TGACCGCTTG 
GTCTACGTGA TCATTGGGAT CTTCTGCCTG GCCTCCTCTA CCGGCCTCTA CAGCTGCCTG 
GCACCCTGTG TGCGCAAGCT GCCCTTCTGC ACGTGCAGGG TCCCCGACAA CAACCTGCCG 
TACTTCCACA AGCGTCCACA GGCCCGCATG CTGCTGCTGG CCCTCTTCTG TGTCACTGTC 
TCCGTGGTGT GGGGTGTCTT CCGTAATGAG GACCAGTGGG CATGGGTCCT GCAGGACACC 
CTGGGCATTG CCTTCTGCCT GTACATGCTG AGGACCATTC GCCTGCCCAC CTTCAAGGTG 
AGGGCTGCCA TGGCAGGGCA GGTCAATTCC TGGTGGGGGG CTGAGGGCCT GGGCGCACAG 
GTCTCGAGGG CAGTGCTGGC TCCCACAGGC CTGCACACTG CTGCTGCTGG TGCTCTTCGT 
CTACGACATC TTCTTCGTCT TCATCACCCC CTACCTGACC AAGGTAGGTC CCCTCTACCC 
TCCCAGCTGC CCGCCCCTCC CCTGCCCTGG CTGACAACCT GTCTTGTGCA GAGCGGCAAC 
AGCATCATGG TGGAGGTGGC CACTGGGCCC TCGAACTCAT CCACCCATGA GAAGCTGCCC 
ATGGTGCTGA AGGTGCCCAG GCTGAACACC TCGCCTCTCT CCCTGTGTGA CCGGCCCTTC 
TCCCTTCTGG GCTTTGGAGA CATCTTGGTG CCAGGGCTGC TGGTGGCCTA CTGCCACAGG 
TTTGATATCC AGGTGCAGTC CTCCAGGATT TACTTTGTGG CCTGCACCAT TGCCTATGGC 
CTGGGCCTCC TGGTGACCTT CGTGGCTCTC GTCCTCATGC GACATGGCCA GCCTGCACTC 
CTCTACTTGG TCCCCTGCAC ACTGCTGACC AGCTGCACCG TGGCTCTGTG GCGCCGGGAG 
ATGGGCGCCT TCTGGACGGG CAGCGGTTTT GCGAAGGATG CACCTCAGAC CCCGTGGGCT 
GCACCCCAGG GACCTGTGCC TCCGAAGGAT GTGGATGCCT CTCTCTCGGA GCAGCCTCGG 
GGTGAAGAGC TGGCCCAGAG CCCCCTGGCC ACTGAGGAGG CAGGAGCCAC AGACCCTGCC 
AAGGATCCTG ACAGCCCTGT GGCCGGTCCC CTCAGCCCCT CAAATGGGGA CCAAGTCCAG 
CCTATACCTG TGGTGACCCC AGGGACCTCG GCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sppl2b ( XM_008765110.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008763332.2 Rattus norvegicus signal peptide peptidase-like 2B (Sppl2b), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa62032
Clone ID Related Accession (Same CDS sequence)	XM_008765110.2
Accession Version	XM_008765110.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1896bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	signal peptide peptidase-like 2B isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008765110.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGCGG CGCGGCTGGC CGCATCCCTG CTGCTACTCG CGGCCCAGGT GGCCTGTGAG 
TTCGGTGTAC TGCGAGTTGT GCCCCAAAGC GGTGGGACCC GGGGCAGGGA CTACTGCATC 
CTTTACAACC CACAGTGGGC CCACTTGCCT CATGACCTCA ACAAAGTGTC TCTTCTGAAG 
CTTCGAGACT TGAGCACGAC TCAGCTCTGT TCCCACCTCG ATGTTCCTGT AGAAGACTTC 
ACCAACCAGA TCGCACTGGT GGCTCGGGGC AACTGTACCT TCTATGAGAA AGTGCGGCTG 
GCCCAGGGCA GTGGGGCACA TGGGCTGCTG ATAGTCAGCA AGGAGAGACT GGTCCCTCCA 
AGAGGCAACA AGACACAGTA TGAGGAGATA AGCATCCCTG TGGCCCTGCT AAGCCACAGG 
GACCTTCAAG ACATCTTCAG GCGCTTTGGC CACGAGGTAA TGGTAGCCCT GTATGCTCCG 
AGCGAGCCAG TGATGGACTA CAACATGGTC ATCATCTTCA TCATGGCCGT GGGCACCGTC 
GCCCTTGGTG GCTACTGGGC TGGCAGTCAT GATGTGAAGA AAAGGTACAT GAAGCATAAG 
CGAGACGACG TCCCTGAGAA GCAGGAGGAT GAGGCGGTGG ACGTGACGCC GGTCATGATC 
TGCGTGTTTG TTGTCATGTG CTGCTTCATG CTTGTGCTCC TCTACTACTT CTATGACCGC 
TTGGTCTACG TGATCATTGG GATCTTCTGC CTGGCCTCCT CTACCGGCCT CTACAGCTGC 
CTGGCACCCT GTGTGCGCAA GCTGCCCTTC TGCACGTGCA GGGTCCCCGA CAACAACCTG 
CCGTACTTCC ACAAGCGTCC ACAGGCCCGC ATGCTGCTGC TGGCCCTCTT CTGTGTCACT 
GTCTCCGTGG TGTGGGGTGT CTTCCGTAAT GAGGACCAGT GGGCATGGGT CCTGCAGGAC 
ACCCTGGGCA TTGCCTTCTG CCTGTACATG CTGAGGACCA TTCGCCTGCC CACCTTCAAG 
GTGAGGGCTG CCATGGCAGG GCAGGTCAAT TCCTGGTGGG GGGCTGAGGG CCTGGGCGCA 
CAGGTCTCGA GGGCAGTGCT GGCTCCCACA GGCCTGCACA CTGCTGCTGC TGGTGCTCTT 
CGTCTACGAC ATCTTCTTCG TCTTCATCAC CCCCTACCTG ACCAAGGTAG GTCCCCTCTA 
CCCTCCCAGC TGCCCGCCCC TCCCCTGCCC TGGCTGACAA CCTGTCTTGT GCAGAGCGGC 
AACAGCATCA TGGTGGAGGT GGCCACTGGG CCCTCGAACT CATCCACCCA TGAGAAGCTG 
CCCATGGTGC TGAAGGTGCC CAGGCTGAAC ACCTCGCCTC TCTCCCTGTG TGACCGGCCC 
TTCTCCCTTC TGGGCTTTGG AGACATCTTG GTGCCAGGGC TGCTGGTGGC CTACTGCCAC 
AGGTTTGATA TCCAGGTGCA GTCCTCCAGG ATTTACTTTG TGGCCTGCAC CATTGCCTAT 
GGCCTGGGCC TCCTGGTGAC CTTCGTGGCT CTCGTCCTCA TGCGACATGG CCAGCCTGCA 
CTCCTCTACT TGGTCCCCTG CACACTGCTG ACCAGCTGCA CCGTGGCTCT GTGGCGCCGG 
GAGATGGGCG CCTTCTGGAC GGGCAGCGGT TTTGCGGATG CACCTCAGAC CCCGTGGGCT 
GCACCCCAGG GACCTGTGCC TCCGAAGGAT GTGGATGCCT CTCTCTCGGA GCAGCCTCGG 
GGTGAAGAGC TGGCCCAGAG CCCCCTGGCC ACTGAGGAGG CAGGAGCCAC AGACCCTGCC 
AAGGATCCTG ACAGCCCTGT GGCCGGTCCC CTCAGCCCCT CAAATGGGGA CCAAGTCCAG 
CCTATACCTG TGGTGACCCC AGGGACCTCG GCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008763332.2
CDS	84..1979
Translation	MAAARLAASLLLLAAQVACEFGVLRVVPQSGGTRGRDYCILYNPQWAHLPHDLNKVSLLKLRDLSTTQLCSHLDVPVEDFTNQIALVARGNCTFYEKVRLAQGSGAHGLLIVSKERLVPPRGNKTQYEEISIPVALLSHRDLQDIFRRFGHEVMVALYAPSEPVMDYNMVIIFIMAVGTVALGGYWAGSHDVKKRYMKHKRDDVPEKQEDEAVDVTPVMICVFVVMCCFMLVLLYYFYDRLVYVIIGIFCLASSTGLYSCLAPCVRKLPFCTCRVPDNNLPYFHKRPQARMLLLALFCVTVSVVWGVFRNEDQWAWVLQDTLGIAFCLYMLRTIRLPTFKVRAAMAGQVNSWWGAEGLGAQVSRAVLAPTGLHTAAAGALRLRHLLRLHHPLPDQGRSPLPSQLPAPPLPWLTTCLVQSGNSIMVEVATGPSNSSTHEKLPMVLKVPRLNTSPLSLCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSSRIYFVACTIAYGLGLLVTFVALVLMRHGQPALLYLVPCTLLTSCTVALWRREMGAFWTGSGFADAPQTPWAAPQGPVPPKDVDASLSEQPRGEELAQSPLATEEAGATDPAKDPDSPVAGPLSPSNGDQVQPIPVVTPGTSA

Target ORF information:

RefSeq Version	XM_008765110.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus signal peptide peptidase-like 2B (Sppl2b), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008765110.2

ORF Insert Sequence:

ATGGCGGCGG CGCGGCTGGC CGCATCCCTG CTGCTACTCG CGGCCCAGGT GGCCTGTGAG 
TTCGGTGTAC TGCGAGTTGT GCCCCAAAGC GGTGGGACCC GGGGCAGGGA CTACTGCATC 
CTTTACAACC CACAGTGGGC CCACTTGCCT CATGACCTCA ACAAAGTGTC TCTTCTGAAG 
CTTCGAGACT TGAGCACGAC TCAGCTCTGT TCCCACCTCG ATGTTCCTGT AGAAGACTTC 
ACCAACCAGA TCGCACTGGT GGCTCGGGGC AACTGTACCT TCTATGAGAA AGTGCGGCTG 
GCCCAGGGCA GTGGGGCACA TGGGCTGCTG ATAGTCAGCA AGGAGAGACT GGTCCCTCCA 
AGAGGCAACA AGACACAGTA TGAGGAGATA AGCATCCCTG TGGCCCTGCT AAGCCACAGG 
GACCTTCAAG ACATCTTCAG GCGCTTTGGC CACGAGGTAA TGGTAGCCCT GTATGCTCCG 
AGCGAGCCAG TGATGGACTA CAACATGGTC ATCATCTTCA TCATGGCCGT GGGCACCGTC 
GCCCTTGGTG GCTACTGGGC TGGCAGTCAT GATGTGAAGA AAAGGTACAT GAAGCATAAG 
CGAGACGACG TCCCTGAGAA GCAGGAGGAT GAGGCGGTGG ACGTGACGCC GGTCATGATC 
TGCGTGTTTG TTGTCATGTG CTGCTTCATG CTTGTGCTCC TCTACTACTT CTATGACCGC 
TTGGTCTACG TGATCATTGG GATCTTCTGC CTGGCCTCCT CTACCGGCCT CTACAGCTGC 
CTGGCACCCT GTGTGCGCAA GCTGCCCTTC TGCACGTGCA GGGTCCCCGA CAACAACCTG 
CCGTACTTCC ACAAGCGTCC ACAGGCCCGC ATGCTGCTGC TGGCCCTCTT CTGTGTCACT 
GTCTCCGTGG TGTGGGGTGT CTTCCGTAAT GAGGACCAGT GGGCATGGGT CCTGCAGGAC 
ACCCTGGGCA TTGCCTTCTG CCTGTACATG CTGAGGACCA TTCGCCTGCC CACCTTCAAG 
GTGAGGGCTG CCATGGCAGG GCAGGTCAAT TCCTGGTGGG GGGCTGAGGG CCTGGGCGCA 
CAGGTCTCGA GGGCAGTGCT GGCTCCCACA GGCCTGCACA CTGCTGCTGC TGGTGCTCTT 
CGTCTACGAC ATCTTCTTCG TCTTCATCAC CCCCTACCTG ACCAAGGTAG GTCCCCTCTA 
CCCTCCCAGC TGCCCGCCCC TCCCCTGCCC TGGCTGACAA CCTGTCTTGT GCAGAGCGGC 
AACAGCATCA TGGTGGAGGT GGCCACTGGG CCCTCGAACT CATCCACCCA TGAGAAGCTG 
CCCATGGTGC TGAAGGTGCC CAGGCTGAAC ACCTCGCCTC TCTCCCTGTG TGACCGGCCC 
TTCTCCCTTC TGGGCTTTGG AGACATCTTG GTGCCAGGGC TGCTGGTGGC CTACTGCCAC 
AGGTTTGATA TCCAGGTGCA GTCCTCCAGG ATTTACTTTG TGGCCTGCAC CATTGCCTAT 
GGCCTGGGCC TCCTGGTGAC CTTCGTGGCT CTCGTCCTCA TGCGACATGG CCAGCCTGCA 
CTCCTCTACT TGGTCCCCTG CACACTGCTG ACCAGCTGCA CCGTGGCTCT GTGGCGCCGG 
GAGATGGGCG CCTTCTGGAC GGGCAGCGGT TTTGCGGATG CACCTCAGAC CCCGTGGGCT 
GCACCCCAGG GACCTGTGCC TCCGAAGGAT GTGGATGCCT CTCTCTCGGA GCAGCCTCGG 
GGTGAAGAGC TGGCCCAGAG CCCCCTGGCC ACTGAGGAGG CAGGAGCCAC AGACCCTGCC 
AAGGATCCTG ACAGCCCTGT GGCCGGTCCC CTCAGCCCCT CAAATGGGGA CCAAGTCCAG 
CCTATACCTG TGGTGACCCC AGGGACCTCG GCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sppl2b ( XM_017594908.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017450397.1 Rattus norvegicus signal peptide peptidase-like 2B (Sppl2b), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa62033
Clone ID Related Accession (Same CDS sequence)	XM_017594908.1
Accession Version	XM_017594908.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1821bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	signal peptide peptidase-like 2B isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGCGG CGCGGCTGGC CGCATCCCTG CTGCTACTCG CGGCCCAGGT GGCCTGTGAG 
TTCGGTGTAC TGCGAGTTGT GCCCCAAAGC GGTGGGACCC GGGGCAGGGA CTACTGCATC 
CTTTACAACC CACAGTGGGC CCACTTGCCT CATGACCTCA ACAAAGTGTC TCTTCTGAAG 
CTTCGAGACT TGAGCACGAC TCAGCTCTGT TCCCACCTCG ATGTTCCTGT AGAAGACTTC 
ACCAACCAGA TCGCACTGGT GGCTCGGGGC AACTGTACCT TCTATGAGAA AGTGCGGCTG 
GCCCAGGGCA GTGGGGCACA TGGGCTGCTG ATAGTCAGCA AGGAGAGACT GGTCCCTCCA 
AGAGGCAACA AGACACAGTA TGAGGAGATA AGCATCCCTG TGGCCCTGCT AAGCCACAGG 
GACCTTCAAG ACATCTTCAG GCGCTTTGGC CACGAGGTAA TGGTAGCCCT GTATGCTCCG 
AGCGAGCCAG TGATGGACTA CAACATGGTC ATCATCTTCA TCATGGCCGT GGGCACCGTC 
GCCCTTGGTG GCTACTGGGC TGGCAGTCAT GATGTGAAGA AAAGGTACAT GAAGCATAAG 
CGAGACGACG TCCCTGAGAA GCAGGAGGAT GAGGCGGTGG ACGTGACGCC GGTCATGATC 
TGCGTGTTTG TTGTCATGTG CTGCTTCATG CTTGTGCTCC TCTACTACTT CTATGACCGC 
TTGGTCTACG TGATCATTGG GATCTTCTGC CTGGCCTCCT CTACCGGCCT CTACAGCTGC 
CTGGCACCCT GTGTGCGCAA GCTGCCCTTC TGCACGTGCA GGGTCCCCGA CAACAACCTG 
CCGTACTTCC ACAAGCGTCC ACAGGCCCGC ATGCTGCTGC TGGCCCTCTT CTGTGTCACT 
GTCTCCGTGG TGTGGGGTGT CTTCCGTAAT GAGGACCAGT GGGCATGGGT CCTGCAGGAC 
ACCCTGGGCA TTGCCTTCTG CCTGTACATG CTGAGGACCA TTCGCCTGCC CACCTTCAAG 
GTGAGGGCTG CCATGGCAGG GCAGGTCAAT TCCTGGTGGG GGGCTGAGGG CCTGGGCGCA 
CAGGTCTCGA GGGCAGTGCT GGCTCCCACA GGCCTGCACA CTGCTGCTGC TGGTGCTCTT 
CGTCTACGAC ATCTTCTTCG TCTTCATCAC CCCCTACCTG ACCAAGGTAG GTCCCCTCTA 
CCCTCCCAGC TGCCCGCCCC TCCCCTGCCC TGGCTGACAA CCTGTCTTGT GCAGAGCGGC 
AACAGCATCA TGGTGGAGGT GGCCACTGGG CCCTCGAACT CATCCACCCA TGAGAAGCTG 
CCCATGGTGC TGAAGGTGCC CAGGCTGAAC ACCTCGCCTC TCTCCCTGTG TGACCGGCCC 
TTCTCCCTTC TGGGCTTTGG AGACATCTTG GTGCCAGCCT ATGGCCTGGG CCTCCTGGTG 
ACCTTCGTGG CTCTCGTCCT CATGCGACAT GGCCAGCCTG CACTCCTCTA CTTGGTCCCC 
TGCACACTGC TGACCAGCTG CACCGTGGCT CTGTGGCGCC GGGAGATGGG CGCCTTCTGG 
ACGGGCAGCG GTTTTGCGAA GGATGCACCT CAGACCCCGT GGGCTGCACC CCAGGGACCT 
GTGCCTCCGA AGGATGTGGA TGCCTCTCTC TCGGAGCAGC CTCGGGGTGA AGAGCTGGCC 
CAGAGCCCCC TGGCCACTGA GGAGGCAGGA GCCACAGACC CTGCCAAGGA TCCTGACAGC 
CCTGTGGCCG GTCCCCTCAG CCCCTCAAAT GGGGACCAAG TCCAGCCTAT ACCTGTGGTG 
ACCCCAGGGA CCTCGGCCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017450397.1
CDS	84..1904
Translation	MAAARLAASLLLLAAQVACEFGVLRVVPQSGGTRGRDYCILYNPQWAHLPHDLNKVSLLKLRDLSTTQLCSHLDVPVEDFTNQIALVARGNCTFYEKVRLAQGSGAHGLLIVSKERLVPPRGNKTQYEEISIPVALLSHRDLQDIFRRFGHEVMVALYAPSEPVMDYNMVIIFIMAVGTVALGGYWAGSHDVKKRYMKHKRDDVPEKQEDEAVDVTPVMICVFVVMCCFMLVLLYYFYDRLVYVIIGIFCLASSTGLYSCLAPCVRKLPFCTCRVPDNNLPYFHKRPQARMLLLALFCVTVSVVWGVFRNEDQWAWVLQDTLGIAFCLYMLRTIRLPTFKVRAAMAGQVNSWWGAEGLGAQVSRAVLAPTGLHTAAAGALRLRHLLRLHHPLPDQGRSPLPSQLPAPPLPWLTTCLVQSGNSIMVEVATGPSNSSTHEKLPMVLKVPRLNTSPLSLCDRPFSLLGFGDILVPAYGLGLLVTFVALVLMRHGQPALLYLVPCTLLTSCTVALWRREMGAFWTGSGFAKDAPQTPWAAPQGPVPPKDVDASLSEQPRGEELAQSPLATEEAGATDPAKDPDSPVAGPLSPSNGDQVQPIPVVTPGTSA

Target ORF information:

RefSeq Version	XM_017594908.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus signal peptide peptidase-like 2B (Sppl2b), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017594908.1

ORF Insert Sequence:

ATGGCGGCGG CGCGGCTGGC CGCATCCCTG CTGCTACTCG CGGCCCAGGT GGCCTGTGAG 
TTCGGTGTAC TGCGAGTTGT GCCCCAAAGC GGTGGGACCC GGGGCAGGGA CTACTGCATC 
CTTTACAACC CACAGTGGGC CCACTTGCCT CATGACCTCA ACAAAGTGTC TCTTCTGAAG 
CTTCGAGACT TGAGCACGAC TCAGCTCTGT TCCCACCTCG ATGTTCCTGT AGAAGACTTC 
ACCAACCAGA TCGCACTGGT GGCTCGGGGC AACTGTACCT TCTATGAGAA AGTGCGGCTG 
GCCCAGGGCA GTGGGGCACA TGGGCTGCTG ATAGTCAGCA AGGAGAGACT GGTCCCTCCA 
AGAGGCAACA AGACACAGTA TGAGGAGATA AGCATCCCTG TGGCCCTGCT AAGCCACAGG 
GACCTTCAAG ACATCTTCAG GCGCTTTGGC CACGAGGTAA TGGTAGCCCT GTATGCTCCG 
AGCGAGCCAG TGATGGACTA CAACATGGTC ATCATCTTCA TCATGGCCGT GGGCACCGTC 
GCCCTTGGTG GCTACTGGGC TGGCAGTCAT GATGTGAAGA AAAGGTACAT GAAGCATAAG 
CGAGACGACG TCCCTGAGAA GCAGGAGGAT GAGGCGGTGG ACGTGACGCC GGTCATGATC 
TGCGTGTTTG TTGTCATGTG CTGCTTCATG CTTGTGCTCC TCTACTACTT CTATGACCGC 
TTGGTCTACG TGATCATTGG GATCTTCTGC CTGGCCTCCT CTACCGGCCT CTACAGCTGC 
CTGGCACCCT GTGTGCGCAA GCTGCCCTTC TGCACGTGCA GGGTCCCCGA CAACAACCTG 
CCGTACTTCC ACAAGCGTCC ACAGGCCCGC ATGCTGCTGC TGGCCCTCTT CTGTGTCACT 
GTCTCCGTGG TGTGGGGTGT CTTCCGTAAT GAGGACCAGT GGGCATGGGT CCTGCAGGAC 
ACCCTGGGCA TTGCCTTCTG CCTGTACATG CTGAGGACCA TTCGCCTGCC CACCTTCAAG 
GTGAGGGCTG CCATGGCAGG GCAGGTCAAT TCCTGGTGGG GGGCTGAGGG CCTGGGCGCA 
CAGGTCTCGA GGGCAGTGCT GGCTCCCACA GGCCTGCACA CTGCTGCTGC TGGTGCTCTT 
CGTCTACGAC ATCTTCTTCG TCTTCATCAC CCCCTACCTG ACCAAGGTAG GTCCCCTCTA 
CCCTCCCAGC TGCCCGCCCC TCCCCTGCCC TGGCTGACAA CCTGTCTTGT GCAGAGCGGC 
AACAGCATCA TGGTGGAGGT GGCCACTGGG CCCTCGAACT CATCCACCCA TGAGAAGCTG 
CCCATGGTGC TGAAGGTGCC CAGGCTGAAC ACCTCGCCTC TCTCCCTGTG TGACCGGCCC 
TTCTCCCTTC TGGGCTTTGG AGACATCTTG GTGCCAGCCT ATGGCCTGGG CCTCCTGGTG 
ACCTTCGTGG CTCTCGTCCT CATGCGACAT GGCCAGCCTG CACTCCTCTA CTTGGTCCCC 
TGCACACTGC TGACCAGCTG CACCGTGGCT CTGTGGCGCC GGGAGATGGG CGCCTTCTGG 
ACGGGCAGCG GTTTTGCGAA GGATGCACCT CAGACCCCGT GGGCTGCACC CCAGGGACCT 
GTGCCTCCGA AGGATGTGGA TGCCTCTCTC TCGGAGCAGC CTCGGGGTGA AGAGCTGGCC 
CAGAGCCCCC TGGCCACTGA GGAGGCAGGA GCCACAGACC CTGCCAAGGA TCCTGACAGC 
CCTGTGGCCG GTCCCCTCAG CCCCTCAAAT GGGGACCAAG TCCAGCCTAT ACCTGTGGTG 
ACCCCAGGGA CCTCGGCCTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sppl2b ( XM_008765116.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008763338.2 Rattus norvegicus signal peptide peptidase-like 2B (Sppl2b), transcript variant X8, mRNA.

Price & Availability↑

CloneID	ORa62034
Clone ID Related Accession (Same CDS sequence)	XM_008765116.2
Accession Version	XM_008765116.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1677bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	signal peptide peptidase-like 2B isoform X7
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008765116.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGCGG CGCGGCTGGC CGCATCCCTG CTGCTACTCG CGGCCCAGGT GGCCTGTGAG 
TTCGGTGTAC TGCGAGTTGT GCCCCAAAGC GGTGGGACCC GGGGCAGGGA CTACTGCATC 
CTTTACAACC CACAGTGGGC CCACTTGCCT CATGACCTCA ACAAAGTGTC TCTTCTGAAG 
CTTCGAGACT TGAGCACGAC TCAGCTCTGT TCCCACCTCG ATGTTCCTGT AGAAGACTTC 
ACCAACCAGA TCGCACTGGT GGCTCGGGGC AACTGTACCT TCTATGAGAA AGTGCGGCTG 
GCCCAGGGCA GTGGGGCACA TGGGCTGCTG ATAGTCAGCA AGGAGAGACT GGTCCCTCCA 
AGAGGCAACA AGACACAGTA TGAGGAGATA AGCATCCCTG TGGCCCTGCT AAGCCACAGG 
GACCTTCAAG ACATCTTCAG GCGCTTTGGC CACGAGGTAA TGGTAGCCCT GTATGCTCCG 
AGCGAGCCAG TGATGGACTA CAACATGGTC ATCATCTTCA TCATGGCCGT GGGCACCGTC 
GCCCTTGGTG GCTACTGGGC TGGCAGTCAT GATGTGAAGA AAAGGTACAT GAAGCATAAG 
CGAGACGACG TCCCTGAGAA GCAGGAGGAT GAGGCGGTGG ACGTGACGCC GGTCATGATC 
TGCGTGTTTG TTGTCATGTG CTGCTTCATG CTTGTGCTCC TCTACTACTT CTATGACCGC 
TTGGTCTACG TGATCATTGG GATCTTCTGC CTGGCCTCCT CTACCGGCCT CTACAGCTGC 
CTGGCACCCT GTGTGCGCAA GCTGCCCTTC TGCACGTGCA GGGTCCCCGA CAACAACCTG 
CCGTACTTCC ACAAGCGTCC ACAGGCCCGC ATGCTGCTGC TGGCCCTCTT CTGTGTCACT 
GTCTCCGTGG TGTGGGGTGT CTTCCGTAAT GAGGACCAGT GGGCATGGGT CCTGCAGGAC 
ACCCTGGGCA TTGCCTTCTG CCTGTACATG CTGAGGACCA TTCGCCTGCC CACCTTCAAG 
GTGAGGGCTG CCATGGCAGG GCAGGTCAAT TCCTGGTGGG GGGCTGAGGG CCTGGGCGCA 
CAGGTCTCGA GGGCAGTGCT GGCTCCCACA GGCCTGCACA CTGCTGCTGC TGGTGCTCTT 
CGTCTACGAC ATCTTCTTCG TCTTCATCAC CCCCTACCTG ACCAAGGTAG GTCCCCTCTA 
CCCTCCCAGC TGCCCGCCCC TCCCCTGCCC TGGCTGACAA CCTGTCTTGT GCAGAGCGGC 
AACAGCATCA TGGTGGAGGT GGCCACTGGG CCCTCGAACT CATCCACCCA TGAGAAGCTG 
CCCATGGTGC TGAAGGTGCC CAGGCTGAAC ACCTCGCCTC TCTCCCTGTG TGACCGGCCC 
TTCTCCCTTC TGGGCTTTGG AGACATCTTG GTGCCAGGGC TGCTGGTGGC CTACTGCCAC 
AGGTTTGATA TCCAGGTGCA GTCCTCCAGG ATTTACTTTG TGGCCTGCAC CATTGCCTAT 
GGCCTGGGCC TCCTGGTGAC CTTCGTGGCT CTCGTCCTCA TGCGACATGG CCAGCCTGCA 
CTCCTCTACT TGGTCCCCTG CACACTGCTG ACCAGCTGCA CCGTGGCTCT GTGGCGCCGG 
GAGATGGGCG CCTTCTGGAC GGGCAGCGGT TTTGCGGTGA ATACCAGTTT GCTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008763338.2
CDS	83..1759
Translation	MAAARLAASLLLLAAQVACEFGVLRVVPQSGGTRGRDYCILYNPQWAHLPHDLNKVSLLKLRDLSTTQLCSHLDVPVEDFTNQIALVARGNCTFYEKVRLAQGSGAHGLLIVSKERLVPPRGNKTQYEEISIPVALLSHRDLQDIFRRFGHEVMVALYAPSEPVMDYNMVIIFIMAVGTVALGGYWAGSHDVKKRYMKHKRDDVPEKQEDEAVDVTPVMICVFVVMCCFMLVLLYYFYDRLVYVIIGIFCLASSTGLYSCLAPCVRKLPFCTCRVPDNNLPYFHKRPQARMLLLALFCVTVSVVWGVFRNEDQWAWVLQDTLGIAFCLYMLRTIRLPTFKVRAAMAGQVNSWWGAEGLGAQVSRAVLAPTGLHTAAAGALRLRHLLRLHHPLPDQGRSPLPSQLPAPPLPWLTTCLVQSGNSIMVEVATGPSNSSTHEKLPMVLKVPRLNTSPLSLCDRPFSLLGFGDILVPGLLVAYCHRFDIQVQSSRIYFVACTIAYGLGLLVTFVALVLMRHGQPALLYLVPCTLLTSCTVALWRREMGAFWTGSGFAVNTSLL

Target ORF information:

RefSeq Version	XM_008765116.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus signal peptide peptidase-like 2B (Sppl2b), transcript variant X8, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008765116.2

ORF Insert Sequence:

ATGGCGGCGG CGCGGCTGGC CGCATCCCTG CTGCTACTCG CGGCCCAGGT GGCCTGTGAG 
TTCGGTGTAC TGCGAGTTGT GCCCCAAAGC GGTGGGACCC GGGGCAGGGA CTACTGCATC 
CTTTACAACC CACAGTGGGC CCACTTGCCT CATGACCTCA ACAAAGTGTC TCTTCTGAAG 
CTTCGAGACT TGAGCACGAC TCAGCTCTGT TCCCACCTCG ATGTTCCTGT AGAAGACTTC 
ACCAACCAGA TCGCACTGGT GGCTCGGGGC AACTGTACCT TCTATGAGAA AGTGCGGCTG 
GCCCAGGGCA GTGGGGCACA TGGGCTGCTG ATAGTCAGCA AGGAGAGACT GGTCCCTCCA 
AGAGGCAACA AGACACAGTA TGAGGAGATA AGCATCCCTG TGGCCCTGCT AAGCCACAGG 
GACCTTCAAG ACATCTTCAG GCGCTTTGGC CACGAGGTAA TGGTAGCCCT GTATGCTCCG 
AGCGAGCCAG TGATGGACTA CAACATGGTC ATCATCTTCA TCATGGCCGT GGGCACCGTC 
GCCCTTGGTG GCTACTGGGC TGGCAGTCAT GATGTGAAGA AAAGGTACAT GAAGCATAAG 
CGAGACGACG TCCCTGAGAA GCAGGAGGAT GAGGCGGTGG ACGTGACGCC GGTCATGATC 
TGCGTGTTTG TTGTCATGTG CTGCTTCATG CTTGTGCTCC TCTACTACTT CTATGACCGC 
TTGGTCTACG TGATCATTGG GATCTTCTGC CTGGCCTCCT CTACCGGCCT CTACAGCTGC 
CTGGCACCCT GTGTGCGCAA GCTGCCCTTC TGCACGTGCA GGGTCCCCGA CAACAACCTG 
CCGTACTTCC ACAAGCGTCC ACAGGCCCGC ATGCTGCTGC TGGCCCTCTT CTGTGTCACT 
GTCTCCGTGG TGTGGGGTGT CTTCCGTAAT GAGGACCAGT GGGCATGGGT CCTGCAGGAC 
ACCCTGGGCA TTGCCTTCTG CCTGTACATG CTGAGGACCA TTCGCCTGCC CACCTTCAAG 
GTGAGGGCTG CCATGGCAGG GCAGGTCAAT TCCTGGTGGG GGGCTGAGGG CCTGGGCGCA 
CAGGTCTCGA GGGCAGTGCT GGCTCCCACA GGCCTGCACA CTGCTGCTGC TGGTGCTCTT 
CGTCTACGAC ATCTTCTTCG TCTTCATCAC CCCCTACCTG ACCAAGGTAG GTCCCCTCTA 
CCCTCCCAGC TGCCCGCCCC TCCCCTGCCC TGGCTGACAA CCTGTCTTGT GCAGAGCGGC 
AACAGCATCA TGGTGGAGGT GGCCACTGGG CCCTCGAACT CATCCACCCA TGAGAAGCTG 
CCCATGGTGC TGAAGGTGCC CAGGCTGAAC ACCTCGCCTC TCTCCCTGTG TGACCGGCCC 
TTCTCCCTTC TGGGCTTTGG AGACATCTTG GTGCCAGGGC TGCTGGTGGC CTACTGCCAC 
AGGTTTGATA TCCAGGTGCA GTCCTCCAGG ATTTACTTTG TGGCCTGCAC CATTGCCTAT 
GGCCTGGGCC TCCTGGTGAC CTTCGTGGCT CTCGTCCTCA TGCGACATGG CCAGCCTGCA 
CTCCTCTACT TGGTCCCCTG CACACTGCTG ACCAGCTGCA CCGTGGCTCT GTGGCGCCGG 
GAGATGGGCG CCTTCTGGAC GGGCAGCGGT TTTGCGGTGA ATACCAGTTT GCTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The ?-helical content of the transmembrane domain of the British dementia protein-2 (Bri2) determines its processing by signal peptide peptidase-like 2b (SPPL2b).
The Journal of biological chemistry287(7)5156-63(2012 Feb)
Fluhrer R,Martin L,Klier B,Haug-Kr?per M,Grammer G,Nuscher B,Haass C

Signal-peptide-peptidase-like 2a (SPPL2a) is targeted to lysosomes/late endosomes by a tyrosine motif in its C-terminal tail.
FEBS letters585(19)2951-7(2011 Oct)
Behnke J,Schneppenheim J,Koch-Nolte F,Haag F,Saftig P,Schr?der B

Substrate requirements for SPPL2b-dependent regulated intramembrane proteolysis.
The Journal of biological chemistry284(9)5662-70(2009 Feb)
Martin L,Fluhrer R,Haass C

Regulated intramembrane proteolysis of Bri2 (Itm2b) by ADAM10 and SPPL2a/SPPL2b.
The Journal of biological chemistry283(3)1644-52(2008 Jan)
Martin L,Fluhrer R,Reiss K,Kremmer E,Saftig P,Haass C

Intramembrane proteolytic cleavage by human signal peptide peptidase like 3 and malaria signal peptide peptidase.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology20(10)1671-9(2006 Aug)
Nyborg AC,Ladd TB,Jansen K,Kukar T,Golde TE

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Sppl2b cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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