Itgb8 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Itgb8
Entrez Gene ID	362800
Full Name	integrin subunit beta 8
General protein information	Preferred Names integrin subunit beta 8 Names integrin beta-8 integrin, beta 8
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 6 Map Location: 6q33

mRNA and Protein(s)

mRNA	Protein	Name
NM_001108726.1	NP_001102196.1	integrin beta-8
XM_006240697.3	XP_006240759.1	integrin beta-8 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ITGB8	XP_518987.2
Gallus gallus (chicken)	ITGB8	XP_003640734.2
Xenopus tropicalis (tropical clawed frog)	itgb8	XP_002933344.2
	ITGB8	XP_001103130.1
Mus musculus (house mouse)	Itgb8	NP_796264.2
Rattus norvegicus (Norway rat)	Itgb8	NP_001102196.1
Homo sapiens (human)	ITGB8	NP_002205.1
Canis lupus familiaris (dog)	ITGB8	XP_532487.1
Bos taurus (cattle)	ITGB8	NP_001179804.1
Danio rerio (zebrafish)	itgb8	XP_001919626.4

Gene Ontology
Bibliography

Related articles in PubMed

TGF? Triggers miR-143/145 Transfer From Smooth Muscle Cells to Endothelial Cells, Thereby Modulating Vessel Stabilization.
Climent M, Quintavalle M, Miragoli M, Chen J, Condorelli G, Elia L
Circulation research116(11)1753-64(2015 May)

[Effect of integrin ?8 on TGF-?1 activation in astrocytes with oxygen glucose deprivation].
Li JH, Li DY, Chen DP, Mu DZ, Qu Y
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics16(1)73-6(2014 Jan)

The changing integrin expression and a role for integrin ?8 in the chondrogenic differentiation of mesenchymal stem cells.
LaPointe VL, Verpoorte A, Stevens MM
PloS one8(11)e82035(2013)

GARP regulates the bioavailability and activation of TGF?.
Wang R, Zhu J, Dong X, Shi M, Lu C, Springer TA
Molecular biology of the cell23(6)1129-39(2012 Mar)

Calcium-sensing receptor modulates cell adhesion and migration via integrins.
Tharmalingam S, Daulat AM, Antflick JE, Ahmed SM, Nemeth EF, Angers S, Conigrave AD, Hampson DR
The Journal of biological chemistry286(47)40922-33(2011 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The highly expressed beta8 plays important roles in the regulation of TGF-beta1 activation in neonatal rats with hypoxic-ischemic brain damage.
Title: [Effect of integrin ?8 on TGF-?1 activation in astrocytes with oxygen glucose deprivation].

The following Itgb8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Itgb8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa00380	NM_001108726.1 Latest version!	Rattus norvegicus integrin subunit beta 8 (Itgb8), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$328.30 $469.00
ORa29707	XM_006240697.3 Latest version!	Rattus norvegicus integrin subunit beta 8 (Itgb8), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Itgb8 ( NM_001108726.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001102196.1 Rattus norvegicus integrin subunit beta 8 (Itgb8), mRNA.

Price & Availability↑

CloneID	ORa00380
Clone ID Related Accession (Same CDS sequence)	NM_001108726.1
Accession Version	NM_001108726.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1683bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	integrin beta-8
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH474038.1. On or before Oct 4, 2007 this sequence version replaced XM_001062206.1, XM_343126.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGCTAAAAA TCCGTCCCCT GAAGAAGTAC CCTGTGGATC TTTATTATCT GGTTGATGTG 
TCAGCATCAA TGCACAATAA TATAGAAAAA TTGAATTCCG TTGGAAACGA TTTATCTAAA 
AAAATGGCCC TTTTTTCCCA TGACTTCCGT CTTGGTTTTG GCTCATATGT GGATAAAACT 
GTCTCACCAT ACATTAGTAT CCACCCGGAA AGGATCCACA ATCAGTGCAG TGACTACAAT 
TTAGACTGTA TGCCTCCCCA TGGATACATT CATGTGCTGT CTCTGACAGA AAACATCACT 
GAGTTTGAAA AAGCAGTCCA CAGACAAAAG ATCTCTGGAA ACATAGACAC TCCTGAAGGA 
GGTTTTGATG CCATGCTTCA GGCTGCCGTC TGTGAGAGTC ATATTGGATG GCGAAAAGAA 
GCTAAAAGAT TGCTGCTGGT GATGACAGAC CAGACATCAC ATCTCGCTCT TGACAGCAAA 
TTGGCAGGCA TAGTGGTGCC AAATGACGGA AACTGCCATC TGAAAAACAA TGTCTACGTC 
AAATCAACAA CCATGGAACA TCCATCATTA GGTCAACTTT CCGAAAAGTT AATAGACAAC 
AACATAAATG TCATTTTTGC AGTTCAAGGA AAGCAGTTTC ATTGGTACAA GGACCTTCTG 
CCCCTTTTGC CTGGTGCCAT TGCTGGTGAA ATAGAATCCA AAGCTGCAAA TCTCAACAAT 
TTAGTAGTAG AAGCCTACAA GGTTCTTTTC AATGTGACAG TTGTGATGAA AACATGTGAT 
ATCATAGGAG GAAAAAACTA TGCAATAATC AAACCTATTG GTTTCAATGA AACCACTAAA 
GTCCACATAC ACAGAAGCTG CAGTTGCCAG TGTGAGGACC ACAGAGGACT CAAAGGACAG 
TGTGCGGAAG CTGCTCCAGA TCCCAAGTGT CCACAGTGTG ATGACGGCAA ATGTCATTTT 
GATGAAGACC AGTTTCCTTC CGAAGCTTGC AAGCCACAGG AGGACCAACC TGTCTGCAGT 
GGCCGAGGTG TTTGTATCTG TGGGAAATGT TTATGTCACA AAACCAAGCT TGGAAGAGTG 
TATGGCCAAT ACTGTGAGAA GGATGACTTC TCTTGTCCCT ATCTCCATGG AGATGTGTGT 
TCTGGACATG GGGAGTGCGA AGGTGGCAGA TGCCAGTGCT TTAACGGCTG GGAAGGGGAT 
CGGTGTCAGT GTCCATCAGC CTCAGCACAG CACTGTGTCA ACTCCAAGGG CCAAGTTTGC 
AGCGGGAGAG GCACCTGCGT TTGTGGCAGG AATTGTCTAC AGTGCCTTCA CCCTCACAAT 
CTGTCTCAAG CTGTTCTTGA TCAGTGTAAA GCCTCCTGTG CTGTCATGGA ACAACATCCT 
GTGGCCCAAA CATCAGAGTG TTTATCTGGC CCAAGCTATC TGCGAATATT TTTCATCATA 
TTCATAGTGA CATTCTTGAT TGGGTTGCTT AAAGTTCTTA TCATTAGACA AGTGATACTA 
CAGTGGAATA GTAATAAAAT AAAGTCCTCA TCAGATTACA GAGTGTCTGC TTCCAAAAAG 
GATAAACTGA TTCTGCAAAG TGTTTGCACG AGAGCTGTAA CCTACCGACG AGAAAAGCCT 
GAGGAAATAA AAATGGATAT CAGCAAACTA AACGCCCAGG AGGCTTTCAG GTGCAACTTC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001102196.1
CDS	1109..2791
Translation	MLKIRPLKKYPVDLYYLVDVSASMHNNIEKLNSVGNDLSKKMALFSHDFRLGFGSYVDKTVSPYISIHPERIHNQCSDYNLDCMPPHGYIHVLSLTENITEFEKAVHRQKISGNIDTPEGGFDAMLQAAVCESHIGWRKEAKRLLLVMTDQTSHLALDSKLAGIVVPNDGNCHLKNNVYVKSTTMEHPSLGQLSEKLIDNNINVIFAVQGKQFHWYKDLLPLLPGAIAGEIESKAANLNNLVVEAYKVLFNVTVVMKTCDIIGGKNYAIIKPIGFNETTKVHIHRSCSCQCEDHRGLKGQCAEAAPDPKCPQCDDGKCHFDEDQFPSEACKPQEDQPVCSGRGVCICGKCLCHKTKLGRVYGQYCEKDDFSCPYLHGDVCSGHGECEGGRCQCFNGWEGDRCQCPSASAQHCVNSKGQVCSGRGTCVCGRNCLQCLHPHNLSQAVLDQCKASCAVMEQHPVAQTSECLSGPSYLRIFFIIFIVTFLIGLLKVLIIRQVILQWNSNKIKSSSDYRVSASKKDKLILQSVCTRAVTYRREKPEEIKMDISKLNAQEAFRCNF

Target ORF information:

RefSeq Version	NM_001108726.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus integrin subunit beta 8 (Itgb8), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108726.1

ORF Insert Sequence:

ATGCTAAAAA TCCGTCCCCT GAAGAAGTAC CCTGTGGATC TTTATTATCT GGTTGATGTG 
TCAGCATCAA TGCACAATAA TATAGAAAAA TTGAATTCCG TTGGAAACGA TTTATCTAAA 
AAAATGGCCC TTTTTTCCCA TGACTTCCGT CTTGGTTTTG GCTCATATGT GGATAAAACT 
GTCTCACCAT ACATTAGTAT CCACCCGGAA AGGATCCACA ATCAGTGCAG TGACTACAAT 
TTAGACTGTA TGCCTCCCCA TGGATACATT CATGTGCTGT CTCTGACAGA AAACATCACT 
GAGTTTGAAA AAGCAGTCCA CAGACAAAAG ATCTCTGGAA ACATAGACAC TCCTGAAGGA 
GGTTTTGATG CCATGCTTCA GGCTGCCGTC TGTGAGAGTC ATATTGGATG GCGAAAAGAA 
GCTAAAAGAT TGCTGCTGGT GATGACAGAC CAGACATCAC ATCTCGCTCT TGACAGCAAA 
TTGGCAGGCA TAGTGGTGCC AAATGACGGA AACTGCCATC TGAAAAACAA TGTCTACGTC 
AAATCAACAA CCATGGAACA TCCATCATTA GGTCAACTTT CCGAAAAGTT AATAGACAAC 
AACATAAATG TCATTTTTGC AGTTCAAGGA AAGCAGTTTC ATTGGTACAA GGACCTTCTG 
CCCCTTTTGC CTGGTGCCAT TGCTGGTGAA ATAGAATCCA AAGCTGCAAA TCTCAACAAT 
TTAGTAGTAG AAGCCTACAA GGTTCTTTTC AATGTGACAG TTGTGATGAA AACATGTGAT 
ATCATAGGAG GAAAAAACTA TGCAATAATC AAACCTATTG GTTTCAATGA AACCACTAAA 
GTCCACATAC ACAGAAGCTG CAGTTGCCAG TGTGAGGACC ACAGAGGACT CAAAGGACAG 
TGTGCGGAAG CTGCTCCAGA TCCCAAGTGT CCACAGTGTG ATGACGGCAA ATGTCATTTT 
GATGAAGACC AGTTTCCTTC CGAAGCTTGC AAGCCACAGG AGGACCAACC TGTCTGCAGT 
GGCCGAGGTG TTTGTATCTG TGGGAAATGT TTATGTCACA AAACCAAGCT TGGAAGAGTG 
TATGGCCAAT ACTGTGAGAA GGATGACTTC TCTTGTCCCT ATCTCCATGG AGATGTGTGT 
TCTGGACATG GGGAGTGCGA AGGTGGCAGA TGCCAGTGCT TTAACGGCTG GGAAGGGGAT 
CGGTGTCAGT GTCCATCAGC CTCAGCACAG CACTGTGTCA ACTCCAAGGG CCAAGTTTGC 
AGCGGGAGAG GCACCTGCGT TTGTGGCAGG AATTGTCTAC AGTGCCTTCA CCCTCACAAT 
CTGTCTCAAG CTGTTCTTGA TCAGTGTAAA GCCTCCTGTG CTGTCATGGA ACAACATCCT 
GTGGCCCAAA CATCAGAGTG TTTATCTGGC CCAAGCTATC TGCGAATATT TTTCATCATA 
TTCATAGTGA CATTCTTGAT TGGGTTGCTT AAAGTTCTTA TCATTAGACA AGTGATACTA 
CAGTGGAATA GTAATAAAAT AAAGTCCTCA TCAGATTACA GAGTGTCTGC TTCCAAAAAG 
GATAAACTGA TTCTGCAAAG TGTTTGCACG AGAGCTGTAA CCTACCGACG AGAAAAGCCT 
GAGGAAATAA AAATGGATAT CAGCAAACTA AACGCCCAGG AGGCTTTCAG GTGCAACTTC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Itgb8 ( XM_006240697.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006240759.1 Rattus norvegicus integrin subunit beta 8 (Itgb8), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa29707
Clone ID Related Accession (Same CDS sequence)	XM_006240697.3
Accession Version	XM_006240697.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2304bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	integrin beta-8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005105.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006240697.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGTGGGT CGGCCCTGGC TTTTCTGACT GCTGCACTGC TCTGCCTGCA CAACTGCCAG 
CGAGGTCCAG CGTTGGTTCT TGGGGCGGCC TGGGTATTTT CACTTGTTCT CGGATTGGGC 
CAAAGTGAAC ATAATAGATG TGACTCTGCA AATGTGGTCT CCTGCGCCAG GTGCCTCCAG 
CTGGGTCCGG AATGTGGATG GTGTGTTCAA GAGGATTTTG TTTCAGGTGG ATCAAGAAGT 
GAACGTTGTG ATACTGTTTC CAATTTGATA AGCAAAGGCT GTCCAGTTGA CTCAATAGAA 
TACCTGTCTG TGCATGTAGT AACATCAAGT GAGAATGAAA TCAATACACA AGTGACTCCG 
GGAGATGTCT CAATCCAACT GCATCCAGGA GCTGAAGCTA ATTTTATGCT AAAAATCCGT 
CCCCTGAAGA AGTACCCTGT GGATCTTTAT TATCTGGTTG ATGTGTCAGC ATCAATGCAC 
AATAATATAG AAAAATTGAA TTCCGTTGGA AACGATTTAT CTAAAAAAAT GGCCCTTTTT 
TCCCATGACT TCCGTCTTGG TTTTGGCTCA TATGTGGATA AAACTGTCTC ACCATACATT 
AGTATCCACC CGGAAAGGAT CCACAATCAG TGCAGTGACT ACAATTTAGA CTGTATGCCT 
CCCCATGGAT ACATTCATGT GCTGTCTCTG ACAGAAAACA TCACTGAGTT TGAAAAAGCA 
GTCCACAGAC AAAAGATCTC TGGAAACATA GACACTCCTG AAGGAGGTTT TGATGCCATG 
CTTCAGGCTG CCGTCTGTGA GAGTCATATT GGATGGCGAA AAGAAGCTAA AAGATTGCTG 
CTGGTGATGA CAGACCAGAC ATCACATCTC GCTCTTGACA GCAAATTGGC AGGCATAGTG 
GTGCCAAATG ACGGAAACTG CCATCTGAAA AACAATGTCT ACGTCAAATC AACAACCATG 
GAACATCCAT CATTAGGTCA ACTTTCCGAA AAGTTAATAG ACAACAACAT AAATGTCATT 
TTTGCAGTTC AAGGAAAGCA GTTTCATTGG TACAAGGACC TTCTGCCCCT TTTGCCTGGT 
GCCATTGCTG GTGAAATAGA ATCCAAAGCT GCAAATCTCA ACAATTTAGT AGTAGAAGCC 
TACAAGAAAC TCATCTCAGA AGTAAAAGTG CAGCTGGAAA GCCAGGTACA CGGTGTCCAT 
TTCAACATCA CTGCCATCTG TCCGGATGGG GCCAGAAAGC CAGGCACAAG TGGGTGTGGA 
AACGTGACAA GCAATGACGA AGTTCTTTTC AATGTGACAG TTGTGATGAA AACATGTGAT 
ATCATAGGAG GAAAAAACTA TGCAATAATC AAACCTATTG GTTTCAATGA AACCACTAAA 
GTCCACATAC ACAGAAGCTG CAGTTGCCAG TGTGAGGACC ACAGAGGACT CAAAGGACAG 
TGTGCGGAAG CTGCTCCAGA TCCCAAGTGT CCACAGTGTG ATGACGGCAA ATGTCATTTT 
GATGAAGACC AGTTTCCTTC CGAAGCTTGC AAGCCACAGG AGGACCAACC TGTCTGCAGT 
GGCCGAGGTG TTTGTATCTG TGGGAAATGT TTATGTCACA AAACCAAGCT TGGAAGAGTG 
TATGGCCAAT ACTGTGAGAA GGATGACTTC TCTTGTCCCT ATCTCCATGG AGATGTGTGT 
TCTGGACATG GGGAGTGCGA AGGTGGCAGA TGCCAGTGCT TTAACGGCTG GGAAGGGGAT 
CGGTGTCAGT GTCCATCAGC CTCAGCACAG CACTGTGTCA ACTCCAAGGG CCAAGTTTGC 
AGCGGGAGAG GCACCTGCGT TTGTGGCAGG TGTGAGTGCA CGGATCCTAG AAGCATCGGC 
CGCCTCTGTG AGCACTGCCC AACCTGCCAT CTCTCCTGCA GTGAAAACTG GAATTGTCTA 
CAGTGCCTTC ACCCTCACAA TCTGTCTCAA GCTGTTCTTG ATCAGTGTAA AGCCTCCTGT 
GCTGTCATGG AACAACATCC TGTGGCCCAA ACATCAGAGT GTTTATCTGG CCCAAGCTAT 
CTGCGAATAT TTTTCATCAT ATTCATAGTG ACATTCTTGA TTGGGTTGCT TAAAGTTCTT 
ATCATTAGAC AAGTGATACT ACAGTGGAAT AGTAATAAAA TAAAGTCCTC ATCAGATTAC 
AGAGTGTCTG CTTCCAAAAA GGATAAACTG ATTCTGCAAA GTGTTTGCAC GAGAGCTGTA 
ACCTACCGAC GAGAAAAGCC TGAGGAAATA AAAATGGATA TCAGCAAACT AAACGCCCAG 
GAGGCTTTCA GGTGCAACTT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006240759.1
CDS	1023..3326
Translation	MCGSALAFLTAALLCLHNCQRGPALVLGAAWVFSLVLGLGQSEHNRCDSANVVSCARCLQLGPECGWCVQEDFVSGGSRSERCDTVSNLISKGCPVDSIEYLSVHVVTSSENEINTQVTPGDVSIQLHPGAEANFMLKIRPLKKYPVDLYYLVDVSASMHNNIEKLNSVGNDLSKKMALFSHDFRLGFGSYVDKTVSPYISIHPERIHNQCSDYNLDCMPPHGYIHVLSLTENITEFEKAVHRQKISGNIDTPEGGFDAMLQAAVCESHIGWRKEAKRLLLVMTDQTSHLALDSKLAGIVVPNDGNCHLKNNVYVKSTTMEHPSLGQLSEKLIDNNINVIFAVQGKQFHWYKDLLPLLPGAIAGEIESKAANLNNLVVEAYKKLISEVKVQLESQVHGVHFNITAICPDGARKPGTSGCGNVTSNDEVLFNVTVVMKTCDIIGGKNYAIIKPIGFNETTKVHIHRSCSCQCEDHRGLKGQCAEAAPDPKCPQCDDGKCHFDEDQFPSEACKPQEDQPVCSGRGVCICGKCLCHKTKLGRVYGQYCEKDDFSCPYLHGDVCSGHGECEGGRCQCFNGWEGDRCQCPSASAQHCVNSKGQVCSGRGTCVCGRCECTDPRSIGRLCEHCPTCHLSCSENWNCLQCLHPHNLSQAVLDQCKASCAVMEQHPVAQTSECLSGPSYLRIFFIIFIVTFLIGLLKVLIIRQVILQWNSNKIKSSSDYRVSASKKDKLILQSVCTRAVTYRREKPEEIKMDISKLNAQEAFRCNF

Target ORF information:

RefSeq Version	XM_006240697.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus integrin subunit beta 8 (Itgb8), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006240697.3

ORF Insert Sequence:

ATGTGTGGGT CGGCCCTGGC TTTTCTGACT GCTGCACTGC TCTGCCTGCA CAACTGCCAG 
CGAGGTCCAG CGTTGGTTCT TGGGGCGGCC TGGGTATTTT CACTTGTTCT CGGATTGGGC 
CAAAGTGAAC ATAATAGATG TGACTCTGCA AATGTGGTCT CCTGCGCCAG GTGCCTCCAG 
CTGGGTCCGG AATGTGGATG GTGTGTTCAA GAGGATTTTG TTTCAGGTGG ATCAAGAAGT 
GAACGTTGTG ATACTGTTTC CAATTTGATA AGCAAAGGCT GTCCAGTTGA CTCAATAGAA 
TACCTGTCTG TGCATGTAGT AACATCAAGT GAGAATGAAA TCAATACACA AGTGACTCCG 
GGAGATGTCT CAATCCAACT GCATCCAGGA GCTGAAGCTA ATTTTATGCT AAAAATCCGT 
CCCCTGAAGA AGTACCCTGT GGATCTTTAT TATCTGGTTG ATGTGTCAGC ATCAATGCAC 
AATAATATAG AAAAATTGAA TTCCGTTGGA AACGATTTAT CTAAAAAAAT GGCCCTTTTT 
TCCCATGACT TCCGTCTTGG TTTTGGCTCA TATGTGGATA AAACTGTCTC ACCATACATT 
AGTATCCACC CGGAAAGGAT CCACAATCAG TGCAGTGACT ACAATTTAGA CTGTATGCCT 
CCCCATGGAT ACATTCATGT GCTGTCTCTG ACAGAAAACA TCACTGAGTT TGAAAAAGCA 
GTCCACAGAC AAAAGATCTC TGGAAACATA GACACTCCTG AAGGAGGTTT TGATGCCATG 
CTTCAGGCTG CCGTCTGTGA GAGTCATATT GGATGGCGAA AAGAAGCTAA AAGATTGCTG 
CTGGTGATGA CAGACCAGAC ATCACATCTC GCTCTTGACA GCAAATTGGC AGGCATAGTG 
GTGCCAAATG ACGGAAACTG CCATCTGAAA AACAATGTCT ACGTCAAATC AACAACCATG 
GAACATCCAT CATTAGGTCA ACTTTCCGAA AAGTTAATAG ACAACAACAT AAATGTCATT 
TTTGCAGTTC AAGGAAAGCA GTTTCATTGG TACAAGGACC TTCTGCCCCT TTTGCCTGGT 
GCCATTGCTG GTGAAATAGA ATCCAAAGCT GCAAATCTCA ACAATTTAGT AGTAGAAGCC 
TACAAGAAAC TCATCTCAGA AGTAAAAGTG CAGCTGGAAA GCCAGGTACA CGGTGTCCAT 
TTCAACATCA CTGCCATCTG TCCGGATGGG GCCAGAAAGC CAGGCACAAG TGGGTGTGGA 
AACGTGACAA GCAATGACGA AGTTCTTTTC AATGTGACAG TTGTGATGAA AACATGTGAT 
ATCATAGGAG GAAAAAACTA TGCAATAATC AAACCTATTG GTTTCAATGA AACCACTAAA 
GTCCACATAC ACAGAAGCTG CAGTTGCCAG TGTGAGGACC ACAGAGGACT CAAAGGACAG 
TGTGCGGAAG CTGCTCCAGA TCCCAAGTGT CCACAGTGTG ATGACGGCAA ATGTCATTTT 
GATGAAGACC AGTTTCCTTC CGAAGCTTGC AAGCCACAGG AGGACCAACC TGTCTGCAGT 
GGCCGAGGTG TTTGTATCTG TGGGAAATGT TTATGTCACA AAACCAAGCT TGGAAGAGTG 
TATGGCCAAT ACTGTGAGAA GGATGACTTC TCTTGTCCCT ATCTCCATGG AGATGTGTGT 
TCTGGACATG GGGAGTGCGA AGGTGGCAGA TGCCAGTGCT TTAACGGCTG GGAAGGGGAT 
CGGTGTCAGT GTCCATCAGC CTCAGCACAG CACTGTGTCA ACTCCAAGGG CCAAGTTTGC 
AGCGGGAGAG GCACCTGCGT TTGTGGCAGG TGTGAGTGCA CGGATCCTAG AAGCATCGGC 
CGCCTCTGTG AGCACTGCCC AACCTGCCAT CTCTCCTGCA GTGAAAACTG GAATTGTCTA 
CAGTGCCTTC ACCCTCACAA TCTGTCTCAA GCTGTTCTTG ATCAGTGTAA AGCCTCCTGT 
GCTGTCATGG AACAACATCC TGTGGCCCAA ACATCAGAGT GTTTATCTGG CCCAAGCTAT 
CTGCGAATAT TTTTCATCAT ATTCATAGTG ACATTCTTGA TTGGGTTGCT TAAAGTTCTT 
ATCATTAGAC AAGTGATACT ACAGTGGAAT AGTAATAAAA TAAAGTCCTC ATCAGATTAC 
AGAGTGTCTG CTTCCAAAAA GGATAAACTG ATTCTGCAAA GTGTTTGCAC GAGAGCTGTA 
ACCTACCGAC GAGAAAAGCC TGAGGAAATA AAAATGGATA TCAGCAAACT AAACGCCCAG 
GAGGCTTTCA GGTGCAACTT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

TGF? Triggers miR-143/145 Transfer From Smooth Muscle Cells to Endothelial Cells, Thereby Modulating Vessel Stabilization.
Circulation research116(11)1753-64(2015 May)
Climent M,Quintavalle M,Miragoli M,Chen J,Condorelli G,Elia L

[Effect of integrin ?8 on TGF-?1 activation in astrocytes with oxygen glucose deprivation].
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics16(1)73-6(2014 Jan)
Li JH,Li DY,Chen DP,Mu DZ,Qu Y

The changing integrin expression and a role for integrin ?8 in the chondrogenic differentiation of mesenchymal stem cells.
PloS one8(11)e82035(2013)
LaPointe VL,Verpoorte A,Stevens MM

GARP regulates the bioavailability and activation of TGF?.
Molecular biology of the cell23(6)1129-39(2012 Mar)
Wang R,Zhu J,Dong X,Shi M,Lu C,Springer TA

Calcium-sensing receptor modulates cell adhesion and migration via integrins.
The Journal of biological chemistry286(47)40922-33(2011 Nov)
Tharmalingam S,Daulat AM,Antflick JE,Ahmed SM,Nemeth EF,Angers S,Conigrave AD,Hampson DR

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Itgb8 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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