Artn cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Artn
Entrez Gene ID	362572
Full Name	artemin
General protein information	Preferred Names artemin Names artemin
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q36

mRNA and Protein(s)

mRNA	Protein	Name
XM_006238685.3	XP_006238747.1	artemin isoform X1
XM_006238691.3	XP_006238753.1	artemin isoform X2
XM_006238687.3	XP_006238749.1	artemin isoform X1
XM_017593494.1	XP_017448983.1	artemin isoform X1
NM_053397.1	NP_445849.1	artemin precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	ARTN	XP_002686562.1
Homo sapiens (human)	ARTN	NP_476431.2
Mus musculus (house mouse)	Artn	NP_033841.1
Pan troglodytes (chimpanzee)	ARTN	XP_001173961.1
	ARTN	XP_002801557.1
Rattus norvegicus (Norway rat)	Artn	NP_445849.1

Gene Ontology
Bibliography

Related articles in PubMed

Artemin transiently increases iNOS expression in primary cultured trigeminal ganglion neurons.
Shang H, Wang Y, Chao X, Sun G, Bai X, Xu L, Han Y, Li J, Wang H, Fan Z
Neuroscience letters66034-38(2017 Nov)

Artemin promotes functional long-distance axonal regeneration to the brainstem after dorsal root crush.
Wong LE, Gibson ME, Arnold HM, Pepinsky B, Frank E
Proceedings of the National Academy of Sciences of the United States of America112(19)6170-5(2015 May)

Peripherally increased artemin is a key regulator of TRPA1/V1 expression in primary afferent neurons.
Ikeda-Miyagawa Y, Kobayashi K, Yamanaka H, Okubo M, Wang S, Dai Y, Yagi H, Hirose M, Noguchi K
Molecular pain118(2015 Mar)

Artemin growth factor increases nicotinic cholinergic receptor subunit expression and activity in nociceptive sensory neurons.
Albers KM, Zhang XL, Diges CM, Schwartz ES, Yang CI, Davis BM, Gold MS
Molecular pain1031(2014 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

artemin has a role in robust regeneration of large, myelinated sensory axons to the brainstem and in promoting functional reinnervation of the cuneate nucleus
Title: Artemin promotes functional long-distance axonal regeneration to the brainstem after dorsal root crush.

indicate the important roles of peripherally-derived artemin on the regulation of TRPV1/A1 in DRG neurons in pathological conditions such as inflammatory and neuropathic pain
Title: Peripherally increased artemin is a key regulator of TRPA1/V1 expression in primary afferent neurons.

This study suggest that Artn regulates the expression and composition of nAChRs in GFRalpha3 nociceptors and that these changes contribute to the thermal hypersensitivity that develops in response to Artn injection and perhaps to inflammation.
Title: Artemin growth factor increases nicotinic cholinergic receptor subunit expression and activity in nociceptive sensory neurons.

These anatomical results support the hypothesis that artemin contributes to dural afferent activity, and possibly migraine pain, through modulation of both primary afferent and sympathetic systems.
Title: Distribution of artemin and GFRalpha3 labeled nerve fibers in the dura mater of rat: artemin and GFRalpha3 in the dura.

Artemin promoted re-entry of multiple classes of sensory fibers into the spinal cord and re-establishment of synaptic function and simple behavior as well as promoted the recovery of complex behavior.
Title: Persistent restoration of sensory function by immediate or delayed systemic artemin after dorsal root injury.

The following Artn gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Artn cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa09442	NM_053397.1 Latest version!	Rattus norvegicus artemin (Artn), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa09442	XM_006238685.3 Latest version!	Rattus norvegicus artemin (Artn), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa09442	XM_017593494.1 Latest version!	Rattus norvegicus artemin (Artn), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa09442	XM_006238687.3 Latest version!	Rattus norvegicus artemin (Artn), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
ORa28487	XM_006238691.3 Latest version!	Rattus norvegicus artemin (Artn), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Artn ( NM_053397.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_445849.1 Rattus norvegicus artemin (Artn), mRNA.

Price & Availability↑

CloneID	ORa09442
Clone ID Related Accession (Same CDS sequence)	XM_006238685.3 , XM_006238687.3 , XM_017593494.1 , NM_053397.1
Accession Version	NM_053397.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-27
Organism	Rattus norvegicus(Norway rat)
Product	artemin precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC079078.1. On Apr 19, 2005 this sequence version replaced XM_342891.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC079078.1, CK476025.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052297, SAMEA2689597 [ECO:0000350] ##Evidence-Data-END##

ATGGAACTGG GACTTGGAGA GCCTACTGCA TTGTCCCACT GCCTCCGGCC TAGGTGGCAA 
CCAGCCTTGT GGCCAACCCT AGCTGCTCTA GCCCTGCTGA GCAGCGTCAC AGAAGCTTCC 
CTGGACCCAA TGTCCCGCAG CCCCGCCTCT CGCGATGTTC CCTCGCCGGT CCTGGCGCCC 
CCAACAGACT ACCTACCTGG GGGACACACC GCACATCTGT GCAGCGAAAG AGCCCTGCGA 
CCACCGCCGC AGTCTCCTCA GCCCGCACCC CCACCACCCG GTCCCGCGCT CCAGTCTCCT 
CCCGCTGCGC TCCGCGGGGC ACGCGCGGCG CGTGCAGGAA CCCGGAGCAG CCGCGCACGG 
GCTACAGATG CGCGCGGCTG CCGCCTGCGC TCACAGCTGG TGCCGGTGAG CGCTCTCGGC 
CTGGGCCACA GCTCCGACGA GCTGATACGT TTCCGCTTCT GCAGCGGTTC GTGCCGCCGA 
GCACGCTCCC CGCACGATCT CAGCCTGGCC AGCCTGCTGG ACGCCGGGGC CCTGCGGTCG 
CCTCCCGGGT CCCGGCCGAT CAGCCAGCCC TGTTGCCGGC CCACTCGCTA TGAGGCCGTC 
TCCTTCATGG ACGTGAACAG CACCTGGAGA ACCGTGGACC ATCTCTCCGC CACCGCCTGC 
GGCTGTCTGG GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_445849.1
CDS	258..932
Translation	MELGLGEPTALSHCLRPRWQPALWPTLAALALLSSVTEASLDPMSRSPASRDVPSPVLAPPTDYLPGGHTAHLCSERALRPPPQSPQPAPPPPGPALQSPPAALRGARAARAGTRSSRARATDARGCRLRSQLVPVSALGLGHSSDELIRFRFCSGSCRRARSPHDLSLASLLDAGALRSPPGSRPISQPCCRPTRYEAVSFMDVNSTWRTVDHLSATACGCLG

Target ORF information:

RefSeq Version	NM_053397.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus artemin (Artn), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053397.1

ORF Insert Sequence:

ATGGAACTGG GACTTGGAGA GCCTACTGCA TTGTCCCACT GCCTCCGGCC TAGGTGGCAA 
CCAGCCTTGT GGCCAACCCT AGCTGCTCTA GCCCTGCTGA GCAGCGTCAC AGAAGCTTCC 
CTGGACCCAA TGTCCCGCAG CCCCGCCTCT CGCGATGTTC CCTCGCCGGT CCTGGCGCCC 
CCAACAGACT ACCTACCTGG GGGACACACC GCACATCTGT GCAGCGAAAG AGCCCTGCGA 
CCACCGCCGC AGTCTCCTCA GCCCGCACCC CCACCACCCG GTCCCGCGCT CCAGTCTCCT 
CCCGCTGCGC TCCGCGGGGC ACGCGCGGCG CGTGCAGGAA CCCGGAGCAG CCGCGCACGG 
GCTACAGATG CGCGCGGCTG CCGCCTGCGC TCACAGCTGG TGCCGGTGAG CGCTCTCGGC 
CTGGGCCACA GCTCCGACGA GCTGATACGT TTCCGCTTCT GCAGCGGTTC GTGCCGCCGA 
GCACGCTCCC CGCACGATCT CAGCCTGGCC AGCCTGCTGG ACGCCGGGGC CCTGCGGTCG 
CCTCCCGGGT CCCGGCCGAT CAGCCAGCCC TGTTGCCGGC CCACTCGCTA TGAGGCCGTC 
TCCTTCATGG ACGTGAACAG CACCTGGAGA ACCGTGGACC ATCTCTCCGC CACCGCCTGC 
GGCTGTCTGG GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Artn ( XM_006238685.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006238747.1 Rattus norvegicus artemin (Artn), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa09442
Clone ID Related Accession (Same CDS sequence)	XM_006238685.3 , XM_006238687.3 , XM_017593494.1 , NM_053397.1
Accession Version	XM_006238685.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	artemin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006238685.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAACTGG GACTTGGAGA GCCTACTGCA TTGTCCCACT GCCTCCGGCC TAGGTGGCAA 
CCAGCCTTGT GGCCAACCCT AGCTGCTCTA GCCCTGCTGA GCAGCGTCAC AGAAGCTTCC 
CTGGACCCAA TGTCCCGCAG CCCCGCCTCT CGCGATGTTC CCTCGCCGGT CCTGGCGCCC 
CCAACAGACT ACCTACCTGG GGGACACACC GCACATCTGT GCAGCGAAAG AGCCCTGCGA 
CCACCGCCGC AGTCTCCTCA GCCCGCACCC CCACCACCCG GTCCCGCGCT CCAGTCTCCT 
CCCGCTGCGC TCCGCGGGGC ACGCGCGGCG CGTGCAGGAA CCCGGAGCAG CCGCGCACGG 
GCTACAGATG CGCGCGGCTG CCGCCTGCGC TCACAGCTGG TGCCGGTGAG CGCTCTCGGC 
CTGGGCCACA GCTCCGACGA GCTGATACGT TTCCGCTTCT GCAGCGGTTC GTGCCGCCGA 
GCACGCTCCC CGCACGATCT CAGCCTGGCC AGCCTGCTGG ACGCCGGGGC CCTGCGGTCG 
CCTCCCGGGT CCCGGCCGAT CAGCCAGCCC TGTTGCCGGC CCACTCGCTA TGAGGCCGTC 
TCCTTCATGG ACGTGAACAG CACCTGGAGA ACCGTGGACC ATCTCTCCGC CACCGCCTGC 
GGCTGTCTGG GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006238747.1
CDS	3591..4265
Translation	MELGLGEPTALSHCLRPRWQPALWPTLAALALLSSVTEASLDPMSRSPASRDVPSPVLAPPTDYLPGGHTAHLCSERALRPPPQSPQPAPPPPGPALQSPPAALRGARAARAGTRSSRARATDARGCRLRSQLVPVSALGLGHSSDELIRFRFCSGSCRRARSPHDLSLASLLDAGALRSPPGSRPISQPCCRPTRYEAVSFMDVNSTWRTVDHLSATACGCLG

Target ORF information:

RefSeq Version	XM_006238685.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus artemin (Artn), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006238685.3

ORF Insert Sequence:

ATGGAACTGG GACTTGGAGA GCCTACTGCA TTGTCCCACT GCCTCCGGCC TAGGTGGCAA 
CCAGCCTTGT GGCCAACCCT AGCTGCTCTA GCCCTGCTGA GCAGCGTCAC AGAAGCTTCC 
CTGGACCCAA TGTCCCGCAG CCCCGCCTCT CGCGATGTTC CCTCGCCGGT CCTGGCGCCC 
CCAACAGACT ACCTACCTGG GGGACACACC GCACATCTGT GCAGCGAAAG AGCCCTGCGA 
CCACCGCCGC AGTCTCCTCA GCCCGCACCC CCACCACCCG GTCCCGCGCT CCAGTCTCCT 
CCCGCTGCGC TCCGCGGGGC ACGCGCGGCG CGTGCAGGAA CCCGGAGCAG CCGCGCACGG 
GCTACAGATG CGCGCGGCTG CCGCCTGCGC TCACAGCTGG TGCCGGTGAG CGCTCTCGGC 
CTGGGCCACA GCTCCGACGA GCTGATACGT TTCCGCTTCT GCAGCGGTTC GTGCCGCCGA 
GCACGCTCCC CGCACGATCT CAGCCTGGCC AGCCTGCTGG ACGCCGGGGC CCTGCGGTCG 
CCTCCCGGGT CCCGGCCGAT CAGCCAGCCC TGTTGCCGGC CCACTCGCTA TGAGGCCGTC 
TCCTTCATGG ACGTGAACAG CACCTGGAGA ACCGTGGACC ATCTCTCCGC CACCGCCTGC 
GGCTGTCTGG GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Artn ( XM_006238687.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006238749.1 Rattus norvegicus artemin (Artn), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa09442
Clone ID Related Accession (Same CDS sequence)	XM_006238685.3 , XM_006238687.3 , XM_017593494.1 , NM_053397.1
Accession Version	XM_006238687.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	artemin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006238687.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAACTGG GACTTGGAGA GCCTACTGCA TTGTCCCACT GCCTCCGGCC TAGGTGGCAA 
CCAGCCTTGT GGCCAACCCT AGCTGCTCTA GCCCTGCTGA GCAGCGTCAC AGAAGCTTCC 
CTGGACCCAA TGTCCCGCAG CCCCGCCTCT CGCGATGTTC CCTCGCCGGT CCTGGCGCCC 
CCAACAGACT ACCTACCTGG GGGACACACC GCACATCTGT GCAGCGAAAG AGCCCTGCGA 
CCACCGCCGC AGTCTCCTCA GCCCGCACCC CCACCACCCG GTCCCGCGCT CCAGTCTCCT 
CCCGCTGCGC TCCGCGGGGC ACGCGCGGCG CGTGCAGGAA CCCGGAGCAG CCGCGCACGG 
GCTACAGATG CGCGCGGCTG CCGCCTGCGC TCACAGCTGG TGCCGGTGAG CGCTCTCGGC 
CTGGGCCACA GCTCCGACGA GCTGATACGT TTCCGCTTCT GCAGCGGTTC GTGCCGCCGA 
GCACGCTCCC CGCACGATCT CAGCCTGGCC AGCCTGCTGG ACGCCGGGGC CCTGCGGTCG 
CCTCCCGGGT CCCGGCCGAT CAGCCAGCCC TGTTGCCGGC CCACTCGCTA TGAGGCCGTC 
TCCTTCATGG ACGTGAACAG CACCTGGAGA ACCGTGGACC ATCTCTCCGC CACCGCCTGC 
GGCTGTCTGG GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006238749.1
CDS	3546..4220
Translation	MELGLGEPTALSHCLRPRWQPALWPTLAALALLSSVTEASLDPMSRSPASRDVPSPVLAPPTDYLPGGHTAHLCSERALRPPPQSPQPAPPPPGPALQSPPAALRGARAARAGTRSSRARATDARGCRLRSQLVPVSALGLGHSSDELIRFRFCSGSCRRARSPHDLSLASLLDAGALRSPPGSRPISQPCCRPTRYEAVSFMDVNSTWRTVDHLSATACGCLG

Target ORF information:

RefSeq Version	XM_006238687.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus artemin (Artn), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006238687.3

ORF Insert Sequence:

ATGGAACTGG GACTTGGAGA GCCTACTGCA TTGTCCCACT GCCTCCGGCC TAGGTGGCAA 
CCAGCCTTGT GGCCAACCCT AGCTGCTCTA GCCCTGCTGA GCAGCGTCAC AGAAGCTTCC 
CTGGACCCAA TGTCCCGCAG CCCCGCCTCT CGCGATGTTC CCTCGCCGGT CCTGGCGCCC 
CCAACAGACT ACCTACCTGG GGGACACACC GCACATCTGT GCAGCGAAAG AGCCCTGCGA 
CCACCGCCGC AGTCTCCTCA GCCCGCACCC CCACCACCCG GTCCCGCGCT CCAGTCTCCT 
CCCGCTGCGC TCCGCGGGGC ACGCGCGGCG CGTGCAGGAA CCCGGAGCAG CCGCGCACGG 
GCTACAGATG CGCGCGGCTG CCGCCTGCGC TCACAGCTGG TGCCGGTGAG CGCTCTCGGC 
CTGGGCCACA GCTCCGACGA GCTGATACGT TTCCGCTTCT GCAGCGGTTC GTGCCGCCGA 
GCACGCTCCC CGCACGATCT CAGCCTGGCC AGCCTGCTGG ACGCCGGGGC CCTGCGGTCG 
CCTCCCGGGT CCCGGCCGAT CAGCCAGCCC TGTTGCCGGC CCACTCGCTA TGAGGCCGTC 
TCCTTCATGG ACGTGAACAG CACCTGGAGA ACCGTGGACC ATCTCTCCGC CACCGCCTGC 
GGCTGTCTGG GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Artn ( XM_017593494.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017448983.1 Rattus norvegicus artemin (Artn), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa09442
Clone ID Related Accession (Same CDS sequence)	XM_006238685.3 , XM_006238687.3 , XM_017593494.1 , NM_053397.1
Accession Version	XM_017593494.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	artemin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAACTGG GACTTGGAGA GCCTACTGCA TTGTCCCACT GCCTCCGGCC TAGGTGGCAA 
CCAGCCTTGT GGCCAACCCT AGCTGCTCTA GCCCTGCTGA GCAGCGTCAC AGAAGCTTCC 
CTGGACCCAA TGTCCCGCAG CCCCGCCTCT CGCGATGTTC CCTCGCCGGT CCTGGCGCCC 
CCAACAGACT ACCTACCTGG GGGACACACC GCACATCTGT GCAGCGAAAG AGCCCTGCGA 
CCACCGCCGC AGTCTCCTCA GCCCGCACCC CCACCACCCG GTCCCGCGCT CCAGTCTCCT 
CCCGCTGCGC TCCGCGGGGC ACGCGCGGCG CGTGCAGGAA CCCGGAGCAG CCGCGCACGG 
GCTACAGATG CGCGCGGCTG CCGCCTGCGC TCACAGCTGG TGCCGGTGAG CGCTCTCGGC 
CTGGGCCACA GCTCCGACGA GCTGATACGT TTCCGCTTCT GCAGCGGTTC GTGCCGCCGA 
GCACGCTCCC CGCACGATCT CAGCCTGGCC AGCCTGCTGG ACGCCGGGGC CCTGCGGTCG 
CCTCCCGGGT CCCGGCCGAT CAGCCAGCCC TGTTGCCGGC CCACTCGCTA TGAGGCCGTC 
TCCTTCATGG ACGTGAACAG CACCTGGAGA ACCGTGGACC ATCTCTCCGC CACCGCCTGC 
GGCTGTCTGG GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017448983.1
CDS	2930..3604
Translation	MELGLGEPTALSHCLRPRWQPALWPTLAALALLSSVTEASLDPMSRSPASRDVPSPVLAPPTDYLPGGHTAHLCSERALRPPPQSPQPAPPPPGPALQSPPAALRGARAARAGTRSSRARATDARGCRLRSQLVPVSALGLGHSSDELIRFRFCSGSCRRARSPHDLSLASLLDAGALRSPPGSRPISQPCCRPTRYEAVSFMDVNSTWRTVDHLSATACGCLG

Target ORF information:

RefSeq Version	XM_017593494.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus artemin (Artn), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017593494.1

ORF Insert Sequence:

ATGGAACTGG GACTTGGAGA GCCTACTGCA TTGTCCCACT GCCTCCGGCC TAGGTGGCAA 
CCAGCCTTGT GGCCAACCCT AGCTGCTCTA GCCCTGCTGA GCAGCGTCAC AGAAGCTTCC 
CTGGACCCAA TGTCCCGCAG CCCCGCCTCT CGCGATGTTC CCTCGCCGGT CCTGGCGCCC 
CCAACAGACT ACCTACCTGG GGGACACACC GCACATCTGT GCAGCGAAAG AGCCCTGCGA 
CCACCGCCGC AGTCTCCTCA GCCCGCACCC CCACCACCCG GTCCCGCGCT CCAGTCTCCT 
CCCGCTGCGC TCCGCGGGGC ACGCGCGGCG CGTGCAGGAA CCCGGAGCAG CCGCGCACGG 
GCTACAGATG CGCGCGGCTG CCGCCTGCGC TCACAGCTGG TGCCGGTGAG CGCTCTCGGC 
CTGGGCCACA GCTCCGACGA GCTGATACGT TTCCGCTTCT GCAGCGGTTC GTGCCGCCGA 
GCACGCTCCC CGCACGATCT CAGCCTGGCC AGCCTGCTGG ACGCCGGGGC CCTGCGGTCG 
CCTCCCGGGT CCCGGCCGAT CAGCCAGCCC TGTTGCCGGC CCACTCGCTA TGAGGCCGTC 
TCCTTCATGG ACGTGAACAG CACCTGGAGA ACCGTGGACC ATCTCTCCGC CACCGCCTGC 
GGCTGTCTGG GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Artn ( XM_006238691.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006238753.1 Rattus norvegicus artemin (Artn), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa28487
Clone ID Related Accession (Same CDS sequence)	XM_006238691.3
Accession Version	XM_006238691.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 597bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	artemin isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006238691.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAACTGG GACTTGGAGA GCCTACTGCA TTGTCCCACT GCCTCCGGCC TAGGTGGCAA 
CCAGCCTTGT GGCCAACCCT AGCTGCTCTA GCCCTGCTGA GCAGCGTCAC AGAAGCTTCC 
CTGGACCCAA TGTCCCGCAG CCCCGCCTCT CGCGATGTTC CCTCGCCGGT CCTGGCGCCC 
CCAACAGACT ACCTACCTGG TAAGGGGACA CACCGCACAT CTGTGCAGCG AAAGAGCCCT 
GCGACCACCG CCGCAGTCTC CTCAGCCCGC ACCCCCACCA CCCGGTCCCG CGCTCCAGTC 
TCCTCCCGCT GCGCTCCGCG GGGCACGCGC GGCGCGTGCA GGAACCCGGA GCAGCCGCGC 
ACGGGCTACA GATGCGCGCG GCTGCCGCCT GCGCTCACAG CTGGTGCCGG TGAGCGCTCT 
CGGCCTGGGC CACAGCTCCG ACGAGCTGAT ACGTTTCCGC TTCTGCAGCG GTTCGTGCCG 
CCGAGCACGC TCCCCGCACG ATCTCAGCCT GGCCAGCCTG CTGGACGCCG GGGCCCTGCG 
GTCGCCTCCC GGGTCCCGGC CGATCAGCCA GCCCTGTTGC CGGCCCACTC GCTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006238753.1
CDS	3813..4409
Translation	MELGLGEPTALSHCLRPRWQPALWPTLAALALLSSVTEASLDPMSRSPASRDVPSPVLAPPTDYLPGKGTHRTSVQRKSPATTAAVSSARTPTTRSRAPVSSRCAPRGTRGACRNPEQPRTGYRCARLPPALTAGAGERSRPGPQLRRADTFPLLQRFVPPSTLPARSQPGQPAGRRGPAVASRVPADQPALLPAHSL

Target ORF information:

RefSeq Version	XM_006238691.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus artemin (Artn), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006238691.3

ORF Insert Sequence:

ATGGAACTGG GACTTGGAGA GCCTACTGCA TTGTCCCACT GCCTCCGGCC TAGGTGGCAA 
CCAGCCTTGT GGCCAACCCT AGCTGCTCTA GCCCTGCTGA GCAGCGTCAC AGAAGCTTCC 
CTGGACCCAA TGTCCCGCAG CCCCGCCTCT CGCGATGTTC CCTCGCCGGT CCTGGCGCCC 
CCAACAGACT ACCTACCTGG TAAGGGGACA CACCGCACAT CTGTGCAGCG AAAGAGCCCT 
GCGACCACCG CCGCAGTCTC CTCAGCCCGC ACCCCCACCA CCCGGTCCCG CGCTCCAGTC 
TCCTCCCGCT GCGCTCCGCG GGGCACGCGC GGCGCGTGCA GGAACCCGGA GCAGCCGCGC 
ACGGGCTACA GATGCGCGCG GCTGCCGCCT GCGCTCACAG CTGGTGCCGG TGAGCGCTCT 
CGGCCTGGGC CACAGCTCCG ACGAGCTGAT ACGTTTCCGC TTCTGCAGCG GTTCGTGCCG 
CCGAGCACGC TCCCCGCACG ATCTCAGCCT GGCCAGCCTG CTGGACGCCG GGGCCCTGCG 
GTCGCCTCCC GGGTCCCGGC CGATCAGCCA GCCCTGTTGC CGGCCCACTC GCTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Artemin transiently increases iNOS expression in primary cultured trigeminal ganglion neurons.
Neuroscience letters66034-38(2017 Nov)
Shang H,Wang Y,Chao X,Sun G,Bai X,Xu L,Han Y,Li J,Wang H,Fan Z

Artemin promotes functional long-distance axonal regeneration to the brainstem after dorsal root crush.
Proceedings of the National Academy of Sciences of the United States of America112(19)6170-5(2015 May)
Wong LE,Gibson ME,Arnold HM,Pepinsky B,Frank E

Peripherally increased artemin is a key regulator of TRPA1/V1 expression in primary afferent neurons.
Molecular pain118(2015 Mar)
Ikeda-Miyagawa Y,Kobayashi K,Yamanaka H,Okubo M,Wang S,Dai Y,Yagi H,Hirose M,Noguchi K

Artemin growth factor increases nicotinic cholinergic receptor subunit expression and activity in nociceptive sensory neurons.
Molecular pain1031(2014 May)
Albers KM,Zhang XL,Diges CM,Schwartz ES,Yang CI,Davis BM,Gold MS

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Artn cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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