Ripk2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Ripk2
Entrez Gene ID	362491
Full Name	receptor-interacting serine-threonine kinase 2
General protein information	Preferred Names receptor-interacting serine-threonine kinase 2 Names receptor-interacting serine/threonine-protein kinase 2 receptor (TNFRSF)-interacting serine-threonine kinase 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q13

mRNA and Protein(s)

mRNA	Protein	Name
NM_001191865.1	NP_001178794.1	receptor-interacting serine/threonine-protein kinase 2
XM_017593470.1	XP_017448959.1	receptor-interacting serine/threonine-protein kinase 2 isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	RIPK2	NP_001029782.1
Danio rerio (zebrafish)	ripk2	NP_919392.2
Canis lupus familiaris (dog)	RIPK2	XP_005638158.1
Mus musculus (house mouse)	Ripk2	NP_620402.1
Pan troglodytes (chimpanzee)	RIPK2	XP_519850.2
	RIPK2	XP_001084687.1
Rattus norvegicus (Norway rat)	Ripk2	NP_001178794.1
Xenopus tropicalis (tropical clawed frog)	ripk2	XP_002939201.2
Homo sapiens (human)	RIPK2	NP_003812.1
Gallus gallus (chicken)	RIPK2	NP_001026114.1

Gene Ontology
Bibliography

Related articles in PubMed

High Glucose and Lipopolysaccharide Activate NOD1- RICK-NF-?B Inflammatory Signaling in Mesangial Cells.
Huang W, Gou F, Long Y, Li Y, Feng H, Zhang Q, Gao C, Chen G, Xu Y
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association124(8)512-517(2016 Sep)

Nod2-Rip2 Signaling Contributes to Intestinal Injury Induced by Muramyl Dipeptide Via Oligopeptide Transporter in Rats.
Ma G, Shi B, Liu J, Zhang H, YinTao Z, Lou X, Liang D, Hou Y, Wan S, Yang W
Digestive diseases and sciences60(11)3264-70(2015 Nov)

The molecular chaperone HSP70 binds to and stabilizes NOD2, an important protein involved in Crohn disease.
Mohanan V, Grimes CL
The Journal of biological chemistry289(27)18987-98(2014 Jul)

OTULIN restricts Met1-linked ubiquitination to control innate immune signaling.
Fiil BK, Damgaard RB, Wagner SA, Keusekotten K, Fritsch M, Bekker-Jensen S, Mailand N, Choudhary C, Komander D, Gyrd-Hansen M
Molecular cell50(6)818-830(2013 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

combined results support the hypothesis that high glucose and LPS can activate the NOD1-RICK-NF-kappaB inflammatory signaling pathway via the NOD1 receptor, and may participate in the development of diabetic nephropathy.
Title: High Glucose and Lipopolysaccharide Activate NOD1- RICK-NF-?B Inflammatory Signaling in Mesangial Cells.

Nod2-Rip2-NFkappaB signaling involved in the small intestinal inflammatory injury caused by muramyl dipeptide which is transported through PepT1.
Title: Nod2-Rip2 Signaling Contributes to Intestinal Injury Induced by Muramyl Dipeptide Via Oligopeptide Transporter in Rats.

The following Ripk2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ripk2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa07869	NM_001191865.1 Latest version!	Rattus norvegicus receptor-interacting serine-threonine kinase 2 (Ripk2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa61289	XM_017593470.1 Latest version!	Rattus norvegicus receptor-interacting serine-threonine kinase 2 (Ripk2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ripk2 ( NM_001191865.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001178794.1 Rattus norvegicus receptor-interacting serine-threonine kinase 2 (Ripk2), mRNA.

Price & Availability↑

CloneID	ORa07869
Clone ID Related Accession (Same CDS sequence)	NM_001191865.1
Accession Version	NM_001191865.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1620bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-08
Organism	Rattus norvegicus(Norway rat)
Product	receptor-interacting serine/threonine-protein kinase 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AABR07047366.1. On Jul 17, 2010 this sequence version replaced XM_342810.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGAACGGGG ACGCCATCTG CAGCGCGCTG CCCCACATCC CCTACCACAA GCTCGCCGAC 
CTGCACTACC TCAGCCGCGG CGCCTCAGGC ACCGTCTCGT CGGCAAGACA CGCGGACTGG 
CGGGTGCGGG TGGCAGTGAA GCACCTGCAC ATTCACACGC CGCTGCTCGA CAGTGAAAGA 
AATGATATCT TACGAGAAGC CGAAATATTA CATAAAGCAA GATTTAGTTA CATTCTTCCA 
ATATTGGGAA TTTGCAATGA GCCTGAATTT TTGGGCATAG TTACTGAATA CATGCCAAAC 
GGATCATTAA ATGAGCTTCT ACACAGAAAA ACTGAATATC CTGAGATTGC ATGGCCATTG 
AGATTCCGCA TCCTGCATGA AATTGCTCTT GGTGTAAATT ACCTGCACAA TATGAACCCC 
CCTCTGCTTC ATCATGACTT AAAGACTCAG AATATCTTGT TGGATAATGA ATTTCATGTT 
AAGATTGCAG ATTTCGGTTT ATCAAAATGG CGCATGATGT CACTCTCCCA ATCACGGAGC 
TACAAATCTG CACCCGAAGG GGGAACGATC ATCTATATGC CACCTGAGAA CTATGAACCG 
GGACAGAAAT CAAGGGCCAG CGTGAAGCAT GATATATACA GCTATGCGGT TATCATGTGG 
GAAGTGTTGT CCAGAAAACA GCCTTTTGAA GAGGTCACCA ATCCTTTGCA GATCATGTAC 
AGTGTGTCCC AGGGACATCG GCCTAACACC AGTGAGGAAA ATTTGCCATT TGATATACCT 
CATCGAGGTC TCATGATCTC TCTAATACAA AGTGGATGGG CACAAAACCC AGATGAGAGA 
CCATCCTTCT TGAAATGCTT AATAGAACTT GAACCAGTTC TGAGAACATT TGAAGACATA 
ACTTTTCTTG AAGCTGTTAT TCAGCTAAAA AAATCAAAGA TACAGAGTGC ATCGAGTACA 
ATTCACTTAT GTGATAAGAA AATGGATTTA TCACTGAACA TACCTGCAAG CCATCCTCCA 
CAGGAGGAAT CATGTGGATC CTCTCTGCTC TCTAGAAACG CTGGTTCTCC TGGAACCTCC 
AGGTCTCTGT CAGCTCCTCA AGACAAAGGT TTTTTCCATG GAGGACCTCA AGACTGTTCT 
TCGTCGAAGG CGTACCATTG TCCTGGAAAT CACAGCTGGG ATGGTATCAT TTCTGTGTCA 
CAAGAGGCAG CCTTCTGTGA TCGCAGAGCC AGCTCGTGCT CCTTGACTGT GATAAGGCCA 
CTGTTGGTTG AGAAAAGTTC AGAGCGCCCA CAACCCGGGA TAGCACAACA GTGGATCCAG 
AGTAAGAGGG AAGCCATTGT GAGCCAGATG ACTGAAGCCT GCCTGAACCA ATCCCTGGAC 
GCCCTTCTGT CTCGGGACCT GATCATGAAG GAGGACTATG AACTCATTAG CACCAAACCT 
ACAAGGACCG CAAAAGTCAG ACAGCTGCTA GATACCTCTG ACATCCAAGG AGAAGAGTTT 
GCCAGAGTTA TAGTACAGAA GTTGAAAGAC AACAAGCAGA TGGGGCTTCA GCCTTACCCG 
GAAGTACTTT TGGTTTCCAG AACACCATCT TCAAATGTCC TTCAAAATAA AACCTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001178794.1
CDS	135..1754
Translation	MNGDAICSALPHIPYHKLADLHYLSRGASGTVSSARHADWRVRVAVKHLHIHTPLLDSERNDILREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPEIAWPLRFRILHEIALGVNYLHNMNPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRMMSLSQSRSYKSAPEGGTIIYMPPENYEPGQKSRASVKHDIYSYAVIMWEVLSRKQPFEEVTNPLQIMYSVSQGHRPNTSEENLPFDIPHRGLMISLIQSGWAQNPDERPSFLKCLIELEPVLRTFEDITFLEAVIQLKKSKIQSASSTIHLCDKKMDLSLNIPASHPPQEESCGSSLLSRNAGSPGTSRSLSAPQDKGFFHGGPQDCSSSKAYHCPGNHSWDGIISVSQEAAFCDRRASSCSLTVIRPLLVEKSSERPQPGIAQQWIQSKREAIVSQMTEACLNQSLDALLSRDLIMKEDYELISTKPTRTAKVRQLLDTSDIQGEEFARVIVQKLKDNKQMGLQPYPEVLLVSRTPSSNVLQNKTL

Target ORF information:

RefSeq Version	NM_001191865.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus receptor-interacting serine-threonine kinase 2 (Ripk2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001191865.1

ORF Insert Sequence:

ATGAACGGGG ACGCCATCTG CAGCGCGCTG CCCCACATCC CCTACCACAA GCTCGCCGAC 
CTGCACTACC TCAGCCGCGG CGCCTCAGGC ACCGTCTCGT CGGCAAGACA CGCGGACTGG 
CGGGTGCGGG TGGCAGTGAA GCACCTGCAC ATTCACACGC CGCTGCTCGA CAGTGAAAGA 
AATGATATCT TACGAGAAGC CGAAATATTA CATAAAGCAA GATTTAGTTA CATTCTTCCA 
ATATTGGGAA TTTGCAATGA GCCTGAATTT TTGGGCATAG TTACTGAATA CATGCCAAAC 
GGATCATTAA ATGAGCTTCT ACACAGAAAA ACTGAATATC CTGAGATTGC ATGGCCATTG 
AGATTCCGCA TCCTGCATGA AATTGCTCTT GGTGTAAATT ACCTGCACAA TATGAACCCC 
CCTCTGCTTC ATCATGACTT AAAGACTCAG AATATCTTGT TGGATAATGA ATTTCATGTT 
AAGATTGCAG ATTTCGGTTT ATCAAAATGG CGCATGATGT CACTCTCCCA ATCACGGAGC 
TACAAATCTG CACCCGAAGG GGGAACGATC ATCTATATGC CACCTGAGAA CTATGAACCG 
GGACAGAAAT CAAGGGCCAG CGTGAAGCAT GATATATACA GCTATGCGGT TATCATGTGG 
GAAGTGTTGT CCAGAAAACA GCCTTTTGAA GAGGTCACCA ATCCTTTGCA GATCATGTAC 
AGTGTGTCCC AGGGACATCG GCCTAACACC AGTGAGGAAA ATTTGCCATT TGATATACCT 
CATCGAGGTC TCATGATCTC TCTAATACAA AGTGGATGGG CACAAAACCC AGATGAGAGA 
CCATCCTTCT TGAAATGCTT AATAGAACTT GAACCAGTTC TGAGAACATT TGAAGACATA 
ACTTTTCTTG AAGCTGTTAT TCAGCTAAAA AAATCAAAGA TACAGAGTGC ATCGAGTACA 
ATTCACTTAT GTGATAAGAA AATGGATTTA TCACTGAACA TACCTGCAAG CCATCCTCCA 
CAGGAGGAAT CATGTGGATC CTCTCTGCTC TCTAGAAACG CTGGTTCTCC TGGAACCTCC 
AGGTCTCTGT CAGCTCCTCA AGACAAAGGT TTTTTCCATG GAGGACCTCA AGACTGTTCT 
TCGTCGAAGG CGTACCATTG TCCTGGAAAT CACAGCTGGG ATGGTATCAT TTCTGTGTCA 
CAAGAGGCAG CCTTCTGTGA TCGCAGAGCC AGCTCGTGCT CCTTGACTGT GATAAGGCCA 
CTGTTGGTTG AGAAAAGTTC AGAGCGCCCA CAACCCGGGA TAGCACAACA GTGGATCCAG 
AGTAAGAGGG AAGCCATTGT GAGCCAGATG ACTGAAGCCT GCCTGAACCA ATCCCTGGAC 
GCCCTTCTGT CTCGGGACCT GATCATGAAG GAGGACTATG AACTCATTAG CACCAAACCT 
ACAAGGACCG CAAAAGTCAG ACAGCTGCTA GATACCTCTG ACATCCAAGG AGAAGAGTTT 
GCCAGAGTTA TAGTACAGAA GTTGAAAGAC AACAAGCAGA TGGGGCTTCA GCCTTACCCG 
GAAGTACTTT TGGTTTCCAG AACACCATCT TCAAATGTCC TTCAAAATAA AACCTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Ripk2 ( XM_017593470.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017448959.1 Rattus norvegicus receptor-interacting serine-threonine kinase 2 (Ripk2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa61289
Clone ID Related Accession (Same CDS sequence)	XM_017593470.1
Accession Version	XM_017593470.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1329bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	receptor-interacting serine/threonine-protein kinase 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCAAACG GATCATTAAA TGAGCTTCTA CACAGAAAAA CTGAATATCC TGAGATTGCA 
TGGCCATTGA GATTCCGCAT CCTGCATGAA ATTGCTCTTG GTGTAAATTA CCTGCACAAT 
ATGAACCCCC CTCTGCTTCA TCATGACTTA AAGACTCAGA ATATCTTGTT GGATAATGAA 
TTTCATGTTA AGATTGCAGA TTTCGGTTTA TCAAAATGGC GCATGATGTC ACTCTCCCAA 
TCACGGAGCT ACAAATCTGC ACCCGAAGGG GGAACGATCA TCTATATGCC ACCTGAGAAC 
TATGAACCGG GACAGAAATC AAGGGCCAGC GTGAAGCATG ATATATACAG CTATGCGGTT 
ATCATGTGGG AAGTGTTGTC CAGAAAACAG CCTTTTGAAG AGGTCACCAA TCCTTTGCAG 
ATCATGTACA GTGTGTCCCA GGGACATCGG CCTAACACCA GTGAGGAAAA TTTGCCATTT 
GATATACCTC ATCGAGGTCT CATGATCTCT CTAATACAAA GTGGATGGGC ACAAAACCCA 
GATGAGAGAC CATCCTTCTT GAAATGCTTA ATAGAACTTG AACCAGTTCT GAGAACATTT 
GAAGACATAA CTTTTCTTGA AGCTGTTATT CAGCTAAAAA AATCAAAGAT ACAGAGTGCA 
TCGAGTACAA TTCACTTATG TGATAAGAAA ATGGATTTAT CACTGAACAT ACCTGCAAGC 
CATCCTCCAC AGGAGGAATC ATGTGGATCC TCTCTGCTCT CTAGAAACGC TGGTTCTCCT 
GGAACCTCCA GGTCTCTGTC AGCTCCTCAA GACAAAGGTT TTTTCCATGG AGGACCTCAA 
GACTGTTCTT CGTCGAAGGC GTACCATTGT CCTGGAAATC ACAGCTGGGA TGGTATCATT 
TCTGTGTCAC AAGAGGCAGC CTTCTGTGAT CGCAGAGCCA GCTCGTGCTC CTTGACTGTG 
ATAAGGCCAC TGTTGGTTGA GAAAAGTTCA GAGCGCCCAC AACCCGGGAT AGCACAACAG 
TGGATCCAGA GTAAGAGGGA AGCCATTGTG AGCCAGATGA CTGAAGCCTG CCTGAACCAA 
TCCCTGGACG CCCTTCTGTC TCGGGACCTG ATCATGAAGG AGGACTATGA ACTCATTAGC 
ACCAAACCTA CAAGGACCGC AAAAGTCAGA CAGCTGCTAG ATACCTCTGA CATCCAAGGA 
GAAGAGTTTG CCAGAGTTAT AGTACAGAAG TTGAAAGACA ACAAGCAGAT GGGGCTTCAG 
CCTTACCCGG AAGTACTTTT GGTTTCCAGA ACACCATCTT CAAATGTCCT TCAAAATAAA 
ACCTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017448959.1
CDS	312..1640
Translation	MPNGSLNELLHRKTEYPEIAWPLRFRILHEIALGVNYLHNMNPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRMMSLSQSRSYKSAPEGGTIIYMPPENYEPGQKSRASVKHDIYSYAVIMWEVLSRKQPFEEVTNPLQIMYSVSQGHRPNTSEENLPFDIPHRGLMISLIQSGWAQNPDERPSFLKCLIELEPVLRTFEDITFLEAVIQLKKSKIQSASSTIHLCDKKMDLSLNIPASHPPQEESCGSSLLSRNAGSPGTSRSLSAPQDKGFFHGGPQDCSSSKAYHCPGNHSWDGIISVSQEAAFCDRRASSCSLTVIRPLLVEKSSERPQPGIAQQWIQSKREAIVSQMTEACLNQSLDALLSRDLIMKEDYELISTKPTRTAKVRQLLDTSDIQGEEFARVIVQKLKDNKQMGLQPYPEVLLVSRTPSSNVLQNKTL

Target ORF information:

RefSeq Version	XM_017593470.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus receptor-interacting serine-threonine kinase 2 (Ripk2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017593470.1

ORF Insert Sequence:

ATGCCAAACG GATCATTAAA TGAGCTTCTA CACAGAAAAA CTGAATATCC TGAGATTGCA 
TGGCCATTGA GATTCCGCAT CCTGCATGAA ATTGCTCTTG GTGTAAATTA CCTGCACAAT 
ATGAACCCCC CTCTGCTTCA TCATGACTTA AAGACTCAGA ATATCTTGTT GGATAATGAA 
TTTCATGTTA AGATTGCAGA TTTCGGTTTA TCAAAATGGC GCATGATGTC ACTCTCCCAA 
TCACGGAGCT ACAAATCTGC ACCCGAAGGG GGAACGATCA TCTATATGCC ACCTGAGAAC 
TATGAACCGG GACAGAAATC AAGGGCCAGC GTGAAGCATG ATATATACAG CTATGCGGTT 
ATCATGTGGG AAGTGTTGTC CAGAAAACAG CCTTTTGAAG AGGTCACCAA TCCTTTGCAG 
ATCATGTACA GTGTGTCCCA GGGACATCGG CCTAACACCA GTGAGGAAAA TTTGCCATTT 
GATATACCTC ATCGAGGTCT CATGATCTCT CTAATACAAA GTGGATGGGC ACAAAACCCA 
GATGAGAGAC CATCCTTCTT GAAATGCTTA ATAGAACTTG AACCAGTTCT GAGAACATTT 
GAAGACATAA CTTTTCTTGA AGCTGTTATT CAGCTAAAAA AATCAAAGAT ACAGAGTGCA 
TCGAGTACAA TTCACTTATG TGATAAGAAA ATGGATTTAT CACTGAACAT ACCTGCAAGC 
CATCCTCCAC AGGAGGAATC ATGTGGATCC TCTCTGCTCT CTAGAAACGC TGGTTCTCCT 
GGAACCTCCA GGTCTCTGTC AGCTCCTCAA GACAAAGGTT TTTTCCATGG AGGACCTCAA 
GACTGTTCTT CGTCGAAGGC GTACCATTGT CCTGGAAATC ACAGCTGGGA TGGTATCATT 
TCTGTGTCAC AAGAGGCAGC CTTCTGTGAT CGCAGAGCCA GCTCGTGCTC CTTGACTGTG 
ATAAGGCCAC TGTTGGTTGA GAAAAGTTCA GAGCGCCCAC AACCCGGGAT AGCACAACAG 
TGGATCCAGA GTAAGAGGGA AGCCATTGTG AGCCAGATGA CTGAAGCCTG CCTGAACCAA 
TCCCTGGACG CCCTTCTGTC TCGGGACCTG ATCATGAAGG AGGACTATGA ACTCATTAGC 
ACCAAACCTA CAAGGACCGC AAAAGTCAGA CAGCTGCTAG ATACCTCTGA CATCCAAGGA 
GAAGAGTTTG CCAGAGTTAT AGTACAGAAG TTGAAAGACA ACAAGCAGAT GGGGCTTCAG 
CCTTACCCGG AAGTACTTTT GGTTTCCAGA ACACCATCTT CAAATGTCCT TCAAAATAAA 
ACCTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

High Glucose and Lipopolysaccharide Activate NOD1- RICK-NF-?B Inflammatory Signaling in Mesangial Cells.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association124(8)512-517(2016 Sep)
Huang W,Gou F,Long Y,Li Y,Feng H,Zhang Q,Gao C,Chen G,Xu Y

Nod2-Rip2 Signaling Contributes to Intestinal Injury Induced by Muramyl Dipeptide Via Oligopeptide Transporter in Rats.
Digestive diseases and sciences60(11)3264-70(2015 Nov)
Ma G,Shi B,Liu J,Zhang H,YinTao Z,Lou X,Liang D,Hou Y,Wan S,Yang W

The molecular chaperone HSP70 binds to and stabilizes NOD2, an important protein involved in Crohn disease.
The Journal of biological chemistry289(27)18987-98(2014 Jul)
Mohanan V,Grimes CL

OTULIN restricts Met1-linked ubiquitination to control innate immune signaling.
Molecular cell50(6)818-830(2013 Jun)
Fiil BK,Damgaard RB,Wagner SA,Keusekotten K,Fritsch M,Bekker-Jensen S,Mailand N,Choudhary C,Komander D,Gyrd-Hansen M

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Ripk2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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