Sumf1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Sumf1
Entrez Gene ID	362409
Full Name	sulfatase modifying factor 1
General protein information	Preferred Names sulfatase modifying factor 1 Names sulfatase-modifying factor 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q41

mRNA and Protein(s)

mRNA	Protein	Name
NM_001108639.1	NP_001102109.1	sulfatase-modifying factor 1 precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Sumf1	NP_666049.2
Rattus norvegicus (Norway rat)	Sumf1	NP_001102109.1
Gallus gallus (chicken)	SUMF1	XP_003642070.1
Pan troglodytes (chimpanzee)	SUMF1	XP_526122.3
Bos taurus (cattle)	SUMF1	NP_001069544.1
Danio rerio (zebrafish)	sumf1	NP_001035430.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP013122	XP_003435826.1
Xenopus tropicalis (tropical clawed frog)	sumf1	NP_001016416.1
Homo sapiens (human)	SUMF1	NP_877437.2
Canis lupus familiaris (dog)	SUMF1	XP_541796.2
Drosophila melanogaster (fruit fly)	CG7049	NP_612003.1

Gene Ontology
Bibliography

Related articles in PubMed

Reconstitution of Formylglycine-generating Enzyme with Copper(II) for Aldehyde Tag Conversion.
Holder PG, Jones LC, Drake PM, Barfield RM, Ba?as S, de Hart GW, Baker J, Rabuka D
The Journal of biological chemistry290(25)15730-45(2015 Jun)

SUMF1 mutations affecting stability and activity of formylglycine generating enzyme predict clinical outcome in multiple sulfatase deficiency.
Schlotawa L, Ennemann EC, Radhakrishnan K, Schmidt B, Chakrapani A, Christen HJ, Moser H, Steinmann B, Dierks T, G?rtner J
European journal of human genetics : EJHG19(3)253-61(2011 Mar)

Paralog of the formylglycine-generating enzyme--retention in the endoplasmic reticulum by canonical and noncanonical signals.
Gande SL, Mariappan M, Schmidt B, Pringle TH, von Figura K, Dierks T
The FEBS journal275(6)1118-30(2008 Mar)

Sulphatase activities are regulated by the interaction of sulphatase-modifying factor 1 with SUMF2.
Zito E, Fraldi A, Pepe S, Annunziata I, Kobinger G, Di Natale P, Ballabio A, Cosma MP
EMBO reports6(7)655-60(2005 Jul)

Multiple sulfatase deficiency is caused by mutations in the gene encoding the human C(alpha)-formylglycine generating enzyme.
Dierks T, Schmidt B, Borissenko LV, Peng J, Preusser A, Mariappan M, von Figura K
Cell113(4)435-44(2003 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Sumf1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sumf1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa07983	NM_001108639.1 Latest version!	Rattus norvegicus sulfatase modifying factor 1 (Sumf1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Sumf1 ( NM_001108639.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001102109.1 Rattus norvegicus sulfatase modifying factor 1 (Sumf1), mRNA.

Price & Availability↑

CloneID	ORa07983
Clone ID Related Accession (Same CDS sequence)	NM_001108639.1
Accession Version	NM_001108639.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1119bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	sulfatase-modifying factor 1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473957.1. On or before Oct 4, 2007 this sequence version replaced XM_342731.3, XM_001078283.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01906352 [ECO:0000348] ##Evidence-Data-END##

ATGGCTGCGC CCGCGGGAGA GCCTGCTCCC CGCTGCTGTA CAGGGCTGGC TCAGGTCTTC 
TTGCTGCTGG TGCTGGCGTG CGGGGCAGCG GGGAGCGATG AGGCCGAGGC CGGGGAAGGT 
GCGGTGTCCC TCGCTGGTTC CTGCGGCTGC GGAACGCCCC AGAGGGCTGG GGCCCATGGC 
AGCTCGGCGG CCGCGCAGCG CTACTCCCGG GAGGCGAATG CCCAGGGCCT GACCTCGGGC 
CCACGATCGC TCGCTCTCAC TAAGATGGTC CCCATCCCTG CTGGAGTATT TACAATGGGC 
ACTGATGATC CTCAGATCAA GCAGGATGGA GAAGCCCCTG CCAGGAGAGT CACTGTCGAT 
GCCTTTTACA TGGATGCCTA TGAAGTCAGC AACGCTGATT TTGAGAAGTT CGTGAACTCA 
ACTGGCTATT TAACAGAGGC TGAGAAGTTT GGAGACTCTT TTGTCTTTGA AGGCATGCTG 
AGTGAGCCAG TCAAGGCGCA AATTCACCAG GCAGTTGCAG CTGCTCCATG GTGGTTACCT 
GTCAAGGGCG CTGATTGGAG ACACCCAGAG GGCCCAGACT CCACTATTCT GCACAGGTCA 
AATCATCCAG TCCTCCATGT CTCCTGGAAT GACGCCGTTG CCTACTGCGC ATGGGCGGGG 
AAGAGGCTGC CCACGGAGGC AGAGTGGGAG TACAGCTGCA GAGGAGGCCT GCAGAACAGG 
CTTTTCCCCT GGGGCAACAA ACTGCAGCCC AAAGGACAGC ATTATGCCAA CATTTGGCAG 
GGCGAGTTTC CTGTGACCAA CACTGGCGAG GATGGCTTCC AAGGAACTGC CCCCGTTGAT 
GCCTTTCCTC CCAATGGCTA TGGCTTATAC AACATAGTGG GGAACGCATG GGAGTGGACC 
TCAGACTGGT GGACCGTTCA CCATTCTGCT GAGGAAACGC TCAACCCAAA AGGCCCCACT 
TCTGGGAAAG ACCGAGTGAA GAAGGGTGGA TCCTACATGT GCCATAAGTC CTATTGCTAC 
AGGTATCGCT GTGCAGCTCG AAGCCAGAAC ACACCAGATA GCTCTGCATC CAACCTGGGA 
TTCCGTTGTG CAGCAGATCA CCTGCCCACT GCAAACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001102109.1
CDS	10..1128
Translation	MAAPAGEPAPRCCTGLAQVFLLLVLACGAAGSDEAEAGEGAVSLAGSCGCGTPQRAGAHGSSAAAQRYSREANAQGLTSGPRSLALTKMVPIPAGVFTMGTDDPQIKQDGEAPARRVTVDAFYMDAYEVSNADFEKFVNSTGYLTEAEKFGDSFVFEGMLSEPVKAQIHQAVAAAPWWLPVKGADWRHPEGPDSTILHRSNHPVLHVSWNDAVAYCAWAGKRLPTEAEWEYSCRGGLQNRLFPWGNKLQPKGQHYANIWQGEFPVTNTGEDGFQGTAPVDAFPPNGYGLYNIVGNAWEWTSDWWTVHHSAEETLNPKGPTSGKDRVKKGGSYMCHKSYCYRYRCAARSQNTPDSSASNLGFRCAADHLPTAN

Target ORF information:

RefSeq Version	NM_001108639.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus sulfatase modifying factor 1 (Sumf1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108639.1

ORF Insert Sequence:

ATGGCTGCGC CCGCGGGAGA GCCTGCTCCC CGCTGCTGTA CAGGGCTGGC TCAGGTCTTC 
TTGCTGCTGG TGCTGGCGTG CGGGGCAGCG GGGAGCGATG AGGCCGAGGC CGGGGAAGGT 
GCGGTGTCCC TCGCTGGTTC CTGCGGCTGC GGAACGCCCC AGAGGGCTGG GGCCCATGGC 
AGCTCGGCGG CCGCGCAGCG CTACTCCCGG GAGGCGAATG CCCAGGGCCT GACCTCGGGC 
CCACGATCGC TCGCTCTCAC TAAGATGGTC CCCATCCCTG CTGGAGTATT TACAATGGGC 
ACTGATGATC CTCAGATCAA GCAGGATGGA GAAGCCCCTG CCAGGAGAGT CACTGTCGAT 
GCCTTTTACA TGGATGCCTA TGAAGTCAGC AACGCTGATT TTGAGAAGTT CGTGAACTCA 
ACTGGCTATT TAACAGAGGC TGAGAAGTTT GGAGACTCTT TTGTCTTTGA AGGCATGCTG 
AGTGAGCCAG TCAAGGCGCA AATTCACCAG GCAGTTGCAG CTGCTCCATG GTGGTTACCT 
GTCAAGGGCG CTGATTGGAG ACACCCAGAG GGCCCAGACT CCACTATTCT GCACAGGTCA 
AATCATCCAG TCCTCCATGT CTCCTGGAAT GACGCCGTTG CCTACTGCGC ATGGGCGGGG 
AAGAGGCTGC CCACGGAGGC AGAGTGGGAG TACAGCTGCA GAGGAGGCCT GCAGAACAGG 
CTTTTCCCCT GGGGCAACAA ACTGCAGCCC AAAGGACAGC ATTATGCCAA CATTTGGCAG 
GGCGAGTTTC CTGTGACCAA CACTGGCGAG GATGGCTTCC AAGGAACTGC CCCCGTTGAT 
GCCTTTCCTC CCAATGGCTA TGGCTTATAC AACATAGTGG GGAACGCATG GGAGTGGACC 
TCAGACTGGT GGACCGTTCA CCATTCTGCT GAGGAAACGC TCAACCCAAA AGGCCCCACT 
TCTGGGAAAG ACCGAGTGAA GAAGGGTGGA TCCTACATGT GCCATAAGTC CTATTGCTAC 
AGGTATCGCT GTGCAGCTCG AAGCCAGAAC ACACCAGATA GCTCTGCATC CAACCTGGGA 
TTCCGTTGTG CAGCAGATCA CCTGCCCACT GCAAACTGA