Nfkbil1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Nfkbil1
Entrez Gene ID	361794
Full Name	NFKB inhibitor like 1
Synonyms	IkBL
General protein information	Preferred Names NFKB inhibitor like 1 Names NF-kappa-B inhibitor-like protein 1 I-kappa-B-like protein ikappaBL inhibitor of kappa B-like protein nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 putative inhibitor of Rel family transcription factors
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 20 Map Location: 20p12
Summary	human homolog is associated with susceptibility for rheumatoid arthritis [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006256046.3	XP_006256108.1	NF-kappa-B inhibitor-like protein 1 isoform X1
NM_212509.2	NP_997674.1	NF-kappa-B inhibitor-like protein 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	NFKBIL1	NP_004998.3
Rattus norvegicus (Norway rat)	Nfkbil1	NP_997674.1
Xenopus tropicalis (tropical clawed frog)	nfkbil1	XP_004916974.1
Danio rerio (zebrafish)	LOC101887110	XP_005155508.1
Pan troglodytes (chimpanzee)	NFKBIL1	NP_001038972.1
Canis lupus familiaris (dog)	NFKBIL1	NP_001014397.1
	NFKBIL1	NP_001040609.1
Bos taurus (cattle)	NFKBIL1	NP_001015597.1
Mus musculus (house mouse)	Nfkbil1	NP_035039.1

Gene Ontology
Bibliography

Related articles in PubMed

I?BL, a novel member of the nuclear I?B family, inhibits inflammatory cytokine expression.
Chiba T, Miyashita K, Sugoh T, Warita T, Inoko H, Kimura M, Sato T
FEBS letters585(22)3577-81(2011 Nov)

Cactin targets the MHC class III protein IkappaB-like (IkappaBL) and inhibits NF-kappaB and interferon-regulatory factor signaling pathways.
Atzei P, Gargan S, Curran N, Moynagh PN
The Journal of biological chemistry285(47)36804-17(2010 Nov)

The genomic sequence and comparative analysis of the rat major histocompatibility complex.
Hurt P, Walter L, Sudbrak R, Klages S, M?ller I, Shiina T, Inoko H, Lehrach H, G?nther E, Reinhardt R, Himmelbauer H
Genome research14(4)631-9(2004 Apr)

Identification of I kappa BL as the second major histocompatibility complex-linked susceptibility locus for rheumatoid arthritis.
Okamoto K, Makino S, Yoshikawa Y, Takaki A, Nagatsuka Y, Ota M, Tamiya G, Kimura A, Bahram S, Inoko H
American journal of human genetics72(2)303-12(2003 Feb)

Does the rat have an H2-D orthologue next to Bat1?
Lambracht-Washington D, Fischer Lindahl K
Immunogenetics53(12)1039-46(2002 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Nfkbil1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nfkbil1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa05698	NM_212509.2 Latest version!	Rattus norvegicus NFKB inhibitor like 1 (Nfkbil1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa39211	XM_006256046.3 Latest version!	Rattus norvegicus NFKB inhibitor like 1 (Nfkbil1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Nfkbil1 ( NM_212509.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_997674.1 Rattus norvegicus NFKB inhibitor like 1 (Nfkbil1), mRNA.

Price & Availability↑

CloneID	ORa05698
Clone ID Related Accession (Same CDS sequence)	NM_212509.2
Accession Version	NM_212509.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1146bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Rattus norvegicus(Norway rat)
Product	NF-kappa-B inhibitor-like protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX883046.1 and BC099772.1. On Oct 2, 2009 this sequence version replaced NM_212509.1. ##Evidence-Data-START## Transcript exon combination :: BC099772.1, CK480351.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGAGTAACC CCTCCCCCCA GGCCCCAGAG GAAGAAGCCT CTACGTCTGT CTGTCGGCCC 
CAGAGTTCCA TGGCCTCCGT TTCCCGCCGG CACCGCCGAG AGCGACGCTT CAGGCGGTAC 
TTGTCTGCAG GACGGCTGGT GCGAGCCCAG GCTCTCCTCC AGCGACATCC CGGCCTTGAT 
GTGGATGCTG GGCAGCCCCC GCCTCTCCAC AGGGCCTGTG CCCGCCACGA TGCCCCTGCC 
CTGTGCTTGC TGCTGCGTCT TGGCGCCGAC CCTGCCCACC AGGACCGCCA TGGGGACACG 
GCGCTGCATG CTGCTGCCCG CCAGGGCCCT AATGCTTACA CGGACTTCTT CCTGCCACTG 
CTGAGTCGAT GCCCATCTGC CATGGGCATA AAGAATAAGG ATGGGGAGAC TCCTGGGCAG 
ATTCTAGGCT GGGGACCTCC CTGGGACTCT GCTGAAGAGG AAGAGGATGA GGAGGTTTCC 
AAGGAGCGGG AATGGCGGCA GAAGCTACAA GGCGAGCTGG AGGATGAGTG GCAGGAGGTC 
ATCGGAAGGT TTGAAGATGA TGCCTCCCGG GAGACGCAGG AGCCCGAGTC CTTCTCAGCC 
TGGTCAGAGC GCCTGGCCCG AGAGCATGCC CAGAAGCAGC GGCGGCAGCA GCTGGAGGCA 
GAGGGATCCC GCCGACCCCC AAGGGCTGAG GGCTCCAGTC ACAGCTGGCG ACAGCAAGAG 
GAGGAGCAGC GGCTTTTCCG GGAGCGAGCC CGGGTCAAGG AGAAGGAACT GTGTGAGAGC 
CGAGCCAGGA GGGCCCAAGA GGCTCAAGGG GACCGAGGGC CAGCGCCTCC CAGGGCCCGG 
CCTAGGGCAG AGCACCCTCG AGGGGCAGGG AGGGGCAGCC TCTGGCGCTT TGGCGATGTG 
CCCTGGCCCT GCCCTGGTGG AGGGGACCCA GAGGCCATGG CTGCAGCTTT GGTGGCCAGG 
GGTCCCCCAC TGGAGGAACA GGGAGCTCTG AAGAGGTACT TAAGAGTCCA GCAGGTCCGA 
TGGCACCCTG ACCGATTCTT GCAGCGATTC CGAAACCAGA TTGAGACCTG GGAGCTGGGC 
CGTGTGATGG GAGCCGTGAC AGCCCTTTCT CAGGCCCTGA ACCGCCATGC AGAAGCCCTC 
AAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_997674.1
CDS	107..1252
Translation	MSNPSPQAPEEEASTSVCRPQSSMASVSRRHRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPNAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEDEEVSKEREWRQKLQGELEDEWQEVIGRFEDDASRETQEPESFSAWSERLAREHAQKQRRQQLEAEGSRRPPRAEGSSHSWRQQEEEQRLFRERARVKEKELCESRARRAQEAQGDRGPAPPRARPRAEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQGALKRYLRVQQVRWHPDRFLQRFRNQIETWELGRVMGAVTALSQALNRHAEALK

Target ORF information:

RefSeq Version	NM_212509.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus NFKB inhibitor like 1 (Nfkbil1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_212509.2

ORF Insert Sequence:

ATGAGTAACC CCTCCCCCCA GGCCCCAGAG GAAGAAGCCT CTACGTCTGT CTGTCGGCCC 
CAGAGTTCCA TGGCCTCCGT TTCCCGCCGG CACCGCCGAG AGCGACGCTT CAGGCGGTAC 
TTGTCTGCAG GACGGCTGGT GCGAGCCCAG GCTCTCCTCC AGCGACATCC CGGCCTTGAT 
GTGGATGCTG GGCAGCCCCC GCCTCTCCAC AGGGCCTGTG CCCGCCACGA TGCCCCTGCC 
CTGTGCTTGC TGCTGCGTCT TGGCGCCGAC CCTGCCCACC AGGACCGCCA TGGGGACACG 
GCGCTGCATG CTGCTGCCCG CCAGGGCCCT AATGCTTACA CGGACTTCTT CCTGCCACTG 
CTGAGTCGAT GCCCATCTGC CATGGGCATA AAGAATAAGG ATGGGGAGAC TCCTGGGCAG 
ATTCTAGGCT GGGGACCTCC CTGGGACTCT GCTGAAGAGG AAGAGGATGA GGAGGTTTCC 
AAGGAGCGGG AATGGCGGCA GAAGCTACAA GGCGAGCTGG AGGATGAGTG GCAGGAGGTC 
ATCGGAAGGT TTGAAGATGA TGCCTCCCGG GAGACGCAGG AGCCCGAGTC CTTCTCAGCC 
TGGTCAGAGC GCCTGGCCCG AGAGCATGCC CAGAAGCAGC GGCGGCAGCA GCTGGAGGCA 
GAGGGATCCC GCCGACCCCC AAGGGCTGAG GGCTCCAGTC ACAGCTGGCG ACAGCAAGAG 
GAGGAGCAGC GGCTTTTCCG GGAGCGAGCC CGGGTCAAGG AGAAGGAACT GTGTGAGAGC 
CGAGCCAGGA GGGCCCAAGA GGCTCAAGGG GACCGAGGGC CAGCGCCTCC CAGGGCCCGG 
CCTAGGGCAG AGCACCCTCG AGGGGCAGGG AGGGGCAGCC TCTGGCGCTT TGGCGATGTG 
CCCTGGCCCT GCCCTGGTGG AGGGGACCCA GAGGCCATGG CTGCAGCTTT GGTGGCCAGG 
GGTCCCCCAC TGGAGGAACA GGGAGCTCTG AAGAGGTACT TAAGAGTCCA GCAGGTCCGA 
TGGCACCCTG ACCGATTCTT GCAGCGATTC CGAAACCAGA TTGAGACCTG GGAGCTGGGC 
CGTGTGATGG GAGCCGTGAC AGCCCTTTCT CAGGCCCTGA ACCGCCATGC AGAAGCCCTC 
AAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Nfkbil1 ( XM_006256046.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006256108.1 Rattus norvegicus NFKB inhibitor like 1 (Nfkbil1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa39211
Clone ID Related Accession (Same CDS sequence)	XM_006256046.3
Accession Version	XM_006256046.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1077bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	NF-kappa-B inhibitor-like protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005119.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006256046.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCTCCG TTTCCCGCCG GCACCGCCGA GAGCGACGCT TCAGGCGGTA CTTGTCTGCA 
GGACGGCTGG TGCGAGCCCA GGCTCTCCTC CAGCGACATC CCGGCCTTGA TGTGGATGCT 
GGGCAGCCCC CGCCTCTCCA CAGGGCCTGT GCCCGCCACG ATGCCCCTGC CCTGTGCTTG 
CTGCTGCGTC TTGGCGCCGA CCCTGCCCAC CAGGACCGCC ATGGGGACAC GGCGCTGCAT 
GCTGCTGCCC GCCAGGGCCC TAATGCTTAC ACGGACTTCT TCCTGCCACT GCTGAGTCGA 
TGCCCATCTG CCATGGGCAT AAAGAATAAG GATGGGGAGA CTCCTGGGCA GATTCTAGGC 
TGGGGACCTC CCTGGGACTC TGCTGAAGAG GAAGAGGATG AGGAGGTTTC CAAGGAGCGG 
GAATGGCGGC AGAAGCTACA AGGCGAGCTG GAGGATGAGT GGCAGGAGGT CATCGGAAGG 
TTTGAAGATG ATGCCTCCCG GGAGACGCAG GAGCCCGAGT CCTTCTCAGC CTGGTCAGAG 
CGCCTGGCCC GAGAGCATGC CCAGAAGCAG CGGCGGCAGC AGCTGGAGGC AGAGGGATCC 
CGCCGACCCC CAAGGGCTGA GGGCTCCAGT CACAGCTGGC GACAGCAAGA GGAGGAGCAG 
CGGCTTTTCC GGGAGCGAGC CCGGGTCAAG GAGAAGGAAC TGTGTGAGAG CCGAGCCAGG 
AGGGCCCAAG AGGCTCAAGG GGACCGAGGG CCAGCGCCTC CCAGGGCCCG GCCTAGGGCA 
GAGCACCCTC GAGGGGCAGG GAGGGGCAGC CTCTGGCGCT TTGGCGATGT GCCCTGGCCC 
TGCCCTGGTG GAGGGGACCC AGAGGCCATG GCTGCAGCTT TGGTGGCCAG GGGTCCCCCA 
CTGGAGGAAC AGGGAGCTCT GAAGAGGTAC TTAAGAGTCC AGCAGGTCCG ATGGCACCCT 
GACCGATTCT TGCAGCGATT CCGAAACCAG ATTGAGACCT GGGAGCTGGG CCGTGTGATG 
GGAGCCGTGA CAGCCCTTTC TCAGGCCCTG AACCGCCATG CAGAAGCCCT CAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006256108.1
CDS	133..1209
Translation	MASVSRRHRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPNAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEDEEVSKEREWRQKLQGELEDEWQEVIGRFEDDASRETQEPESFSAWSERLAREHAQKQRRQQLEAEGSRRPPRAEGSSHSWRQQEEEQRLFRERARVKEKELCESRARRAQEAQGDRGPAPPRARPRAEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQGALKRYLRVQQVRWHPDRFLQRFRNQIETWELGRVMGAVTALSQALNRHAEALK

Target ORF information:

RefSeq Version	XM_006256046.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus NFKB inhibitor like 1 (Nfkbil1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006256046.3

ORF Insert Sequence:

ATGGCCTCCG TTTCCCGCCG GCACCGCCGA GAGCGACGCT TCAGGCGGTA CTTGTCTGCA 
GGACGGCTGG TGCGAGCCCA GGCTCTCCTC CAGCGACATC CCGGCCTTGA TGTGGATGCT 
GGGCAGCCCC CGCCTCTCCA CAGGGCCTGT GCCCGCCACG ATGCCCCTGC CCTGTGCTTG 
CTGCTGCGTC TTGGCGCCGA CCCTGCCCAC CAGGACCGCC ATGGGGACAC GGCGCTGCAT 
GCTGCTGCCC GCCAGGGCCC TAATGCTTAC ACGGACTTCT TCCTGCCACT GCTGAGTCGA 
TGCCCATCTG CCATGGGCAT AAAGAATAAG GATGGGGAGA CTCCTGGGCA GATTCTAGGC 
TGGGGACCTC CCTGGGACTC TGCTGAAGAG GAAGAGGATG AGGAGGTTTC CAAGGAGCGG 
GAATGGCGGC AGAAGCTACA AGGCGAGCTG GAGGATGAGT GGCAGGAGGT CATCGGAAGG 
TTTGAAGATG ATGCCTCCCG GGAGACGCAG GAGCCCGAGT CCTTCTCAGC CTGGTCAGAG 
CGCCTGGCCC GAGAGCATGC CCAGAAGCAG CGGCGGCAGC AGCTGGAGGC AGAGGGATCC 
CGCCGACCCC CAAGGGCTGA GGGCTCCAGT CACAGCTGGC GACAGCAAGA GGAGGAGCAG 
CGGCTTTTCC GGGAGCGAGC CCGGGTCAAG GAGAAGGAAC TGTGTGAGAG CCGAGCCAGG 
AGGGCCCAAG AGGCTCAAGG GGACCGAGGG CCAGCGCCTC CCAGGGCCCG GCCTAGGGCA 
GAGCACCCTC GAGGGGCAGG GAGGGGCAGC CTCTGGCGCT TTGGCGATGT GCCCTGGCCC 
TGCCCTGGTG GAGGGGACCC AGAGGCCATG GCTGCAGCTT TGGTGGCCAG GGGTCCCCCA 
CTGGAGGAAC AGGGAGCTCT GAAGAGGTAC TTAAGAGTCC AGCAGGTCCG ATGGCACCCT 
GACCGATTCT TGCAGCGATT CCGAAACCAG ATTGAGACCT GGGAGCTGGG CCGTGTGATG 
GGAGCCGTGA CAGCCCTTTC TCAGGCCCTG AACCGCCATG CAGAAGCCCT CAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

I?BL, a novel member of the nuclear I?B family, inhibits inflammatory cytokine expression.
FEBS letters585(22)3577-81(2011 Nov)
Chiba T,Miyashita K,Sugoh T,Warita T,Inoko H,Kimura M,Sato T

Cactin targets the MHC class III protein IkappaB-like (IkappaBL) and inhibits NF-kappaB and interferon-regulatory factor signaling pathways.
The Journal of biological chemistry285(47)36804-17(2010 Nov)
Atzei P,Gargan S,Curran N,Moynagh PN

The genomic sequence and comparative analysis of the rat major histocompatibility complex.
Genome research14(4)631-9(2004 Apr)
Hurt P,Walter L,Sudbrak R,Klages S,M?ller I,Shiina T,Inoko H,Lehrach H,G?nther E,Reinhardt R,Himmelbauer H

Identification of I kappa BL as the second major histocompatibility complex-linked susceptibility locus for rheumatoid arthritis.
American journal of human genetics72(2)303-12(2003 Feb)
Okamoto K,Makino S,Yoshikawa Y,Takaki A,Nagatsuka Y,Ota M,Tamiya G,Kimura A,Bahram S,Inoko H

Does the rat have an H2-D orthologue next to Bat1?
Immunogenetics53(12)1039-46(2002 Mar)
Lambracht-Washington D,Fischer Lindahl K

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Nfkbil1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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