Kdelr1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kdelr1
Entrez Gene ID	361577
Full Name	KDEL endoplasmic reticulum protein retention receptor 1
General protein information	Preferred Names KDEL endoplasmic reticulum protein retention receptor 1 Names ER lumen protein-retaining receptor 1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 KDEL receptor 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q22

mRNA and Protein(s)

mRNA	Protein	Name
NM_001017385.1	NP_001017385.1	ER lumen protein-retaining receptor 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	KDELR1	NP_006792.1
	KDELR1	XP_001113600.1
Eremothecium gossypii	AGOS_AGL323C	NP_986344.1
Schizosaccharomyces pombe (fission yeast)	erd2	NP_596529.1
Magnaporthe oryzae (rice blast fungus)	MGG_16126	XP_003709210.1
Bos taurus (cattle)	KDELR1	NP_001069963.1
Mus musculus (house mouse)	Kdelr1	NP_598711.1
Kluyveromyces lactis	KLLA0E05611g	XP_454199.1
Neurospora crassa	NCU06771	XP_963612.1
Oryza sativa (rice)	Os05g0529300	NP_001056121.1
Rattus norvegicus (Norway rat)	Kdelr1	NP_001017385.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012756	XP_307101.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010224	XP_319412.2
Canis lupus familiaris (dog)	KDELR1	XP_541521.2
Saccharomyces cerevisiae (baker's yeast)	ERD2	NP_009513.1
Arabidopsis thaliana (thale cress)	ERD2	NP_564326.1
Xenopus tropicalis (tropical clawed frog)	kdelr2	NP_001011046.1
Pan troglodytes (chimpanzee)	KDELR1	XP_001170972.1
Drosophila melanogaster (fruit fly)	KdelR	NP_723587.1

Gene Ontology
Bibliography

Related articles in PubMed

Mutation of the ER retention receptor KDELR1 leads to cell-intrinsic lymphopenia and a failure to control chronic viral infection.
Siggs OM, Popkin DL, Krebs P, Li X, Tang M, Zhan X, Zeng M, Lin P, Xia Y, Oldstone MB, Cornall RJ, Beutler B
Proceedings of the National Academy of Sciences of the United States of America112(42)E5706-14(2015 Oct)

Sox9 plays multiple roles in the lung epithelium during branching morphogenesis.
Rockich BE, Hrycaj SM, Shih HP, Nagy MS, Ferguson MA, Kopp JL, Sander M, Wellik DM, Spence JR
Proceedings of the National Academy of Sciences of the United States of America110(47)E4456-64(2013 Nov)

Sorting receptor Rer1 controls surface expression of muscle acetylcholine receptors by ER retention of unassembled alpha-subunits.
Valkova C, Albrizio M, R?der IV, Schwake M, Betto R, Rudolf R, Kaether C
Proceedings of the National Academy of Sciences of the United States of America108(2)621-5(2011 Jan)

UBXD4, a UBX-containing protein, regulates the cell surface number and stability of alpha3-containing nicotinic acetylcholine receptors.
Rezvani K, Teng Y, Pan Y, Dani JA, Lindstrom J, Garc?a Gras EA, McIntosh JM, De Biasi M
The Journal of neuroscience : the official journal of the Society for Neuroscience29(21)6883-96(2009 May)

A molecular specificity code for the three mammalian KDEL receptors.
Raykhel I, Alanen H, Salo K, Jurvansuu J, Nguyen VD, Latva-Ranta M, Ruddock L
The Journal of cell biology179(6)1193-204(2007 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Kdelr1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kdelr1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa13838	NM_001017385.1 Latest version!	Rattus norvegicus KDEL endoplasmic reticulum protein retention receptor 1 (Kdelr1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kdelr1 ( NM_001017385.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001017385.1 Rattus norvegicus KDEL endoplasmic reticulum protein retention receptor 1 (Kdelr1), mRNA.

Price & Availability↑

CloneID	ORa13838
Clone ID Related Accession (Same CDS sequence)	NM_001017385.1
Accession Version	NM_001017385.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 639bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Rattus norvegicus(Norway rat)
Product	ER lumen protein-retaining receptor 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC092600.1. On Apr 22, 2005 this sequence version replaced XM_341860.2. ##Evidence-Data-START## Transcript exon combination :: BC092600.1, FQ213542.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGAACCTCT TCCGATTCCT GGGAGACCTC TCCCACCTCC TAGCTATCAT CTTGTTACTG 
CTCAAAATCT GGAAGTCCCG ATCGTGTGCG GGCATTTCAG GGAAGAGCCA AGTCCTGTTT 
GCTGTGGTGT TCACTGCCCG ATATCTGGAC CTGTTCACCA ACTACATTTC ACTCTACAAT 
ACCTGCATGA AGGTGGTCTA CATAGCTTGT TCCTTTACCA CGGTGTGGAT GATCTACAGC 
AAGTTCAAAG CTACGTATGA TGGGAACCAC GACACTTTCC GGGTGGAGTT CCTCGTTGTT 
CCTACTGCTG TTTTGGCGTT CCTGGTTAAC CATGACTTCA CCCCTCTGGA GATCCTCTGG 
ACTTTCTCCA TCTACCTGGA GTCAGTGGCT ATCTTGCCAC AGCTGTTCAT GGTGAGCAAG 
ACGGGCGAGG CAGAGACCAT CACCAGCCAT TACCTGTTCG CACTGGGTGT CTACCGTACA 
CTCTATCTCT TCAACTGGAT CTGGCGCTAC CACTTCGAGG GCTTCTTTGA CCTCATCGCC 
ATTGTTGCTG GCCTGGTCCA GACAGTCCTC TACTGCGATT TCTTCTACCT CTACATCACC 
AAAGTCCTAA AGGGGAAGAA GCTGAGCTTG CCGGCGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001017385.1
CDS	90..728
Translation	MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYNTCMKVVYIACSFTTVWMIYSKFKATYDGNHDTFRVEFLVVPTAVLAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA

Target ORF information:

RefSeq Version	NM_001017385.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus KDEL endoplasmic reticulum protein retention receptor 1 (Kdelr1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001017385.1

ORF Insert Sequence:

ATGAACCTCT TCCGATTCCT GGGAGACCTC TCCCACCTCC TAGCTATCAT CTTGTTACTG 
CTCAAAATCT GGAAGTCCCG ATCGTGTGCG GGCATTTCAG GGAAGAGCCA AGTCCTGTTT 
GCTGTGGTGT TCACTGCCCG ATATCTGGAC CTGTTCACCA ACTACATTTC ACTCTACAAT 
ACCTGCATGA AGGTGGTCTA CATAGCTTGT TCCTTTACCA CGGTGTGGAT GATCTACAGC 
AAGTTCAAAG CTACGTATGA TGGGAACCAC GACACTTTCC GGGTGGAGTT CCTCGTTGTT 
CCTACTGCTG TTTTGGCGTT CCTGGTTAAC CATGACTTCA CCCCTCTGGA GATCCTCTGG 
ACTTTCTCCA TCTACCTGGA GTCAGTGGCT ATCTTGCCAC AGCTGTTCAT GGTGAGCAAG 
ACGGGCGAGG CAGAGACCAT CACCAGCCAT TACCTGTTCG CACTGGGTGT CTACCGTACA 
CTCTATCTCT TCAACTGGAT CTGGCGCTAC CACTTCGAGG GCTTCTTTGA CCTCATCGCC 
ATTGTTGCTG GCCTGGTCCA GACAGTCCTC TACTGCGATT TCTTCTACCT CTACATCACC 
AAAGTCCTAA AGGGGAAGAA GCTGAGCTTG CCGGCGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mutation of the ER retention receptor KDELR1 leads to cell-intrinsic lymphopenia and a failure to control chronic viral infection.
Proceedings of the National Academy of Sciences of the United States of America112(42)E5706-14(2015 Oct)
Siggs OM,Popkin DL,Krebs P,Li X,Tang M,Zhan X,Zeng M,Lin P,Xia Y,Oldstone MB,Cornall RJ,Beutler B

Sox9 plays multiple roles in the lung epithelium during branching morphogenesis.
Proceedings of the National Academy of Sciences of the United States of America110(47)E4456-64(2013 Nov)
Rockich BE,Hrycaj SM,Shih HP,Nagy MS,Ferguson MA,Kopp JL,Sander M,Wellik DM,Spence JR

Sorting receptor Rer1 controls surface expression of muscle acetylcholine receptors by ER retention of unassembled alpha-subunits.
Proceedings of the National Academy of Sciences of the United States of America108(2)621-5(2011 Jan)
Valkova C,Albrizio M,R?der IV,Schwake M,Betto R,Rudolf R,Kaether C

UBXD4, a UBX-containing protein, regulates the cell surface number and stability of alpha3-containing nicotinic acetylcholine receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience29(21)6883-96(2009 May)
Rezvani K,Teng Y,Pan Y,Dani JA,Lindstrom J,Garc?a Gras EA,McIntosh JM,De Biasi M

A molecular specificity code for the three mammalian KDEL receptors.
The Journal of cell biology179(6)1193-204(2007 Dec)
Raykhel I,Alanen H,Salo K,Jurvansuu J,Nguyen VD,Latva-Ranta M,Ruddock L

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Kdelr1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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