Snrnp70 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Snrnp70
Entrez Gene ID	361574
Full Name	small nuclear ribonucleoprotein U1 subunit 70
Synonyms	Snrp70
General protein information	Preferred Names small nuclear ribonucleoprotein U1 subunit 70 Names U1 small nuclear ribonucleoprotein 70 kDa U1 small nuclear ribonucleoprotein polypeptide A small nuclear ribonucleoprotein 70 (U1)
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q22

mRNA and Protein(s)

mRNA	Protein	Name
XM_006229101.3	XP_006229163.1	U1 small nuclear ribonucleoprotein 70 kDa isoform X1
XM_006229102.3	XP_006229164.1	U1 small nuclear ribonucleoprotein 70 kDa isoform X1
NM_001108483.1	NP_001101953.1	U1 small nuclear ribonucleoprotein 70 kDa

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SNRNP70	XP_001156213.2
Bos taurus (cattle)	SNRNP70	NP_001069514.1
Rattus norvegicus (Norway rat)	Snrnp70	NP_001101953.1
Homo sapiens (human)	SNRNP70	NP_003080.2
	SNRNP70	XP_001112732.2
Canis lupus familiaris (dog)	SNRNP70	XP_005616386.1
Mus musculus (house mouse)	Snrnp70	NP_033250.3

Gene Ontology
Bibliography

Related articles in PubMed

Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition.
Kondo Y, Oubridge C, van Roon AM, Nagai K
eLife4(2015 Jan)

U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease.
Bai B, Hales CM, Chen PC, Gozal Y, Dammer EB, Fritz JJ, Wang X, Xia Q, Duong DM, Street C, Cantero G, Cheng D, Jones DR, Wu Z, Li Y, Diner I, Heilman CJ, Rees HD, Wu H, Lin L, Szulwach KE, Gearing M, Mufson EJ, Bennett DA, Montine TJ, Seyfried NT, Wingo TS, Sun YE, Jin P, Hanfelt J, Willcock DM, Levey A, Lah JJ, Peng J
Proceedings of the National Academy of Sciences of the United States of America110(41)16562-7(2013 Oct)

The nuclear cap-binding complex interacts with the U4/U6?U5 tri-snRNP and promotes spliceosome assembly in mammalian cells.
Pabis M, Neufeld N, Steiner MC, Bojic T, Shav-Tal Y, Neugebauer KM
RNA (New York, N.Y.)19(8)1054-63(2013 Aug)

A broadly applicable high-throughput screening strategy identifies new regulators of Dlg4 (Psd-95) alternative splicing.
Zheng S, Damoiseaux R, Chen L, Black DL
Genome research23(6)998-1007(2013 Jun)

Structural analyses of the pre-mRNA splicing machinery.
Zhang L, Li X, Zhao R
Protein science : a publication of the Protein Society22(6)677-92(2013 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Snrnp70 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Snrnp70 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa07465	NM_001108483.1 Latest version!	Rattus norvegicus small nuclear ribonucleoprotein U1 subunit 70 (Snrnp70), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa22749	XM_006229101.3 Latest version!	Rattus norvegicus small nuclear ribonucleoprotein U1 subunit 70 (Snrnp70), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
ORa22749	XM_006229102.3 Latest version!	Rattus norvegicus small nuclear ribonucleoprotein U1 subunit 70 (Snrnp70), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Snrnp70 ( NM_001108483.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101953.1 Rattus norvegicus small nuclear ribonucleoprotein U1 subunit 70 (Snrnp70), mRNA.

Price & Availability↑

CloneID	ORa07465
Clone ID Related Accession (Same CDS sequence)	NM_001108483.1
Accession Version	NM_001108483.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 501bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	U1 small nuclear ribonucleoprotein 70 kDa
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473979.2. On or before Oct 4, 2007 this sequence version replaced XM_341857.3, XM_001079238.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: CB616047.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGACACAGT TTCTGCCTCC CAACCTTCTG GCCCTTTTTG CACCCCGAGA CCCCATCCCA 
TACCTGCCAC CCCTGGAAAA GCTGCCACAT GAAAAACACC ATAACCAACC TTACTGTGGC 
ATTGCACCAT ATATCCGAGA GTTTGAGGAC CCTCGAGATG CCCCTCCTCC AACAAGGGCA 
GAAACCCGGG AAGAACGCAT GGAGAGAAAG AGACGGGAAA AAATTGAACG GCGACAGCAG 
GAAGTGGAGA CAGAGCTGAA AATGTGGGAC CCTCACAATG ATCCCAATGC TCAGGGCGAT 
GCCTTCAAGA CTCTGTTCGT GGCTAGAGTG AACTATGACA CAACAGAATC TAAGCTGCGA 
AGAGAGTTTG AGGTGTACGG ACCCATCAAA AGAATCCACA TGGTCTACAG TAAACGCTCT 
GGGAAACCCC GTGGTTATGC CTTCATCGAG TATGAGCATG AACGAGACAT GCACTCCACC 
ACGCAGCTGG CTTGCAGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101953.1
CDS	276..776
Translation	MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSTTQLACS

Target ORF information:

RefSeq Version	NM_001108483.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus small nuclear ribonucleoprotein U1 subunit 70 (Snrnp70), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108483.1

ORF Insert Sequence:

ATGACACAGT TTCTGCCTCC CAACCTTCTG GCCCTTTTTG CACCCCGAGA CCCCATCCCA 
TACCTGCCAC CCCTGGAAAA GCTGCCACAT GAAAAACACC ATAACCAACC TTACTGTGGC 
ATTGCACCAT ATATCCGAGA GTTTGAGGAC CCTCGAGATG CCCCTCCTCC AACAAGGGCA 
GAAACCCGGG AAGAACGCAT GGAGAGAAAG AGACGGGAAA AAATTGAACG GCGACAGCAG 
GAAGTGGAGA CAGAGCTGAA AATGTGGGAC CCTCACAATG ATCCCAATGC TCAGGGCGAT 
GCCTTCAAGA CTCTGTTCGT GGCTAGAGTG AACTATGACA CAACAGAATC TAAGCTGCGA 
AGAGAGTTTG AGGTGTACGG ACCCATCAAA AGAATCCACA TGGTCTACAG TAAACGCTCT 
GGGAAACCCC GTGGTTATGC CTTCATCGAG TATGAGCATG AACGAGACAT GCACTCCACC 
ACGCAGCTGG CTTGCAGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Snrnp70 ( XM_006229101.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006229163.1 Rattus norvegicus small nuclear ribonucleoprotein U1 subunit 70 (Snrnp70), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa22749
Clone ID Related Accession (Same CDS sequence)	XM_006229101.3 , XM_006229102.3
Accession Version	XM_006229101.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1356bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	U1 small nuclear ribonucleoprotein 70 kDa isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006229101.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACACAGT TTCTGCCTCC CAACCTTCTG GCCCTTTTTG CACCCCGAGA CCCCATCCCA 
TACCTGCCAC CCCTGGAAAA GCTGCCACAT GAAAAACACC ATAACCAACC TTACTGTGGC 
ATTGCACCAT ATATCCGAGA GTTTGAGGAC CCTCGAGATG CCCCTCCTCC AACAAGGGCA 
GAAACCCGGG AAGAACGCAT GGAGAGAAAG AGACGGGAAA AAATTGAACG GCGACAGCAG 
GAAGTGGAGA CAGAGCTGAA AATGTGGGAC CCTCACAATG ATCCCAATGC TCAGGGCGAT 
GCCTTCAAGA CTCTGTTCGT GGCTAGAGTG AACTATGACA CAACAGAATC TAAGCTGCGA 
AGAGAGTTTG AGGTGTACGG ACCCATCAAA AGAATCCACA TGGTCTACAG TAAACGCTCT 
GGGAAACCCC GTGGTTATGC CTTCATCGAG TATGAGCATG AACGAGACAT GCACTCCGCT 
TACAAGCACG CAGATGGCAA GAAGATAGAT GGCAGGAGGG TCCTCGTGGA TGTGGAGAGG 
GGCCGGACTG TGAAGGGCTG GAGGCCCCGG CGGCTAGGAG GTGGCCTTGG TGGTACCAGA 
AGAGGTGGGG CAGATGTGAA TATCAGGCAT TCAGGCCGAG ATGACACTTC CCGATATGAT 
GAGAGGCCGG GCCCCTCCCC GCTTCCACAC AGAGACCGGG ACCGGGACCG CGAGCGGGAG 
CGCAGAGAAA GAAGCCGAGA GCGAGACAAG GAGAGAGAAA GGAGACGCTC CCGCTCTCGG 
GACCGGAGGA GGCGCTCTCG GAGTCGAGAC AAGGATGAGC GGCGCCGATC CAGAGAGCGA 
AGCAAGGACA AAGACAGAGA TCGAAAGCGT CGAAGTAGTC GGAGCCGGGA GCGAGCACGC 
AGGGAGCGGG AGCGAAAAGA GGAGCTTCGA GGCGGAGGAG GAGGTGGTGG TGGTGGTGGT 
GGTGGCGGCG GCGGAGGCGG TGGAGGCGAC ATGGCTGAAC CCTCTGAAGC TGGTGATGGA 
GCTCCTGATG ATGGGCCTCC TGGAGAGCTT GGCCCTGAAG GCCCTGATGG CCCTGAGGAG 
AAGGGTCGGG ATCGAGACCG GGAGAGGCGT CGAAGTCACC GAAGTGAGAG GGAACGCCGT 
CGGGACCGAG ACCGTGACCG GGATAGAGAG CACAAGCGTG GGGAGCGGGG CAGTGAGCGG 
GGCAGGGATG AGGCCCGGGG TGGGGGTGGC AGCGGTCAGG ACAATGGGCT GGAAGGGCTA 
GGTAGTGATG GTCGAGACAT GTACATGGAG GCCGAGGGTG GGGATGGGTA CATGGCCCCA 
GAGAACGGAT ATCTGATGGA GGCAGCGCCT GAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006229163.1
CDS	219..1574
Translation	MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKDERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGGGGGGGGGGGGGGGGDMAEPSEAGDGAPDDGPPGELGPEGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDREHKRGERGSERGRDEARGGGGSGQDNGLEGLGSDGRDMYMEAEGGDGYMAPENGYLMEAAPE

Target ORF information:

RefSeq Version	XM_006229101.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus small nuclear ribonucleoprotein U1 subunit 70 (Snrnp70), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006229101.3

ORF Insert Sequence:

ATGACACAGT TTCTGCCTCC CAACCTTCTG GCCCTTTTTG CACCCCGAGA CCCCATCCCA 
TACCTGCCAC CCCTGGAAAA GCTGCCACAT GAAAAACACC ATAACCAACC TTACTGTGGC 
ATTGCACCAT ATATCCGAGA GTTTGAGGAC CCTCGAGATG CCCCTCCTCC AACAAGGGCA 
GAAACCCGGG AAGAACGCAT GGAGAGAAAG AGACGGGAAA AAATTGAACG GCGACAGCAG 
GAAGTGGAGA CAGAGCTGAA AATGTGGGAC CCTCACAATG ATCCCAATGC TCAGGGCGAT 
GCCTTCAAGA CTCTGTTCGT GGCTAGAGTG AACTATGACA CAACAGAATC TAAGCTGCGA 
AGAGAGTTTG AGGTGTACGG ACCCATCAAA AGAATCCACA TGGTCTACAG TAAACGCTCT 
GGGAAACCCC GTGGTTATGC CTTCATCGAG TATGAGCATG AACGAGACAT GCACTCCGCT 
TACAAGCACG CAGATGGCAA GAAGATAGAT GGCAGGAGGG TCCTCGTGGA TGTGGAGAGG 
GGCCGGACTG TGAAGGGCTG GAGGCCCCGG CGGCTAGGAG GTGGCCTTGG TGGTACCAGA 
AGAGGTGGGG CAGATGTGAA TATCAGGCAT TCAGGCCGAG ATGACACTTC CCGATATGAT 
GAGAGGCCGG GCCCCTCCCC GCTTCCACAC AGAGACCGGG ACCGGGACCG CGAGCGGGAG 
CGCAGAGAAA GAAGCCGAGA GCGAGACAAG GAGAGAGAAA GGAGACGCTC CCGCTCTCGG 
GACCGGAGGA GGCGCTCTCG GAGTCGAGAC AAGGATGAGC GGCGCCGATC CAGAGAGCGA 
AGCAAGGACA AAGACAGAGA TCGAAAGCGT CGAAGTAGTC GGAGCCGGGA GCGAGCACGC 
AGGGAGCGGG AGCGAAAAGA GGAGCTTCGA GGCGGAGGAG GAGGTGGTGG TGGTGGTGGT 
GGTGGCGGCG GCGGAGGCGG TGGAGGCGAC ATGGCTGAAC CCTCTGAAGC TGGTGATGGA 
GCTCCTGATG ATGGGCCTCC TGGAGAGCTT GGCCCTGAAG GCCCTGATGG CCCTGAGGAG 
AAGGGTCGGG ATCGAGACCG GGAGAGGCGT CGAAGTCACC GAAGTGAGAG GGAACGCCGT 
CGGGACCGAG ACCGTGACCG GGATAGAGAG CACAAGCGTG GGGAGCGGGG CAGTGAGCGG 
GGCAGGGATG AGGCCCGGGG TGGGGGTGGC AGCGGTCAGG ACAATGGGCT GGAAGGGCTA 
GGTAGTGATG GTCGAGACAT GTACATGGAG GCCGAGGGTG GGGATGGGTA CATGGCCCCA 
GAGAACGGAT ATCTGATGGA GGCAGCGCCT GAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Snrnp70 ( XM_006229102.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006229164.1 Rattus norvegicus small nuclear ribonucleoprotein U1 subunit 70 (Snrnp70), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa22749
Clone ID Related Accession (Same CDS sequence)	XM_006229101.3 , XM_006229102.3
Accession Version	XM_006229102.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1356bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	U1 small nuclear ribonucleoprotein 70 kDa isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006229102.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACACAGT TTCTGCCTCC CAACCTTCTG GCCCTTTTTG CACCCCGAGA CCCCATCCCA 
TACCTGCCAC CCCTGGAAAA GCTGCCACAT GAAAAACACC ATAACCAACC TTACTGTGGC 
ATTGCACCAT ATATCCGAGA GTTTGAGGAC CCTCGAGATG CCCCTCCTCC AACAAGGGCA 
GAAACCCGGG AAGAACGCAT GGAGAGAAAG AGACGGGAAA AAATTGAACG GCGACAGCAG 
GAAGTGGAGA CAGAGCTGAA AATGTGGGAC CCTCACAATG ATCCCAATGC TCAGGGCGAT 
GCCTTCAAGA CTCTGTTCGT GGCTAGAGTG AACTATGACA CAACAGAATC TAAGCTGCGA 
AGAGAGTTTG AGGTGTACGG ACCCATCAAA AGAATCCACA TGGTCTACAG TAAACGCTCT 
GGGAAACCCC GTGGTTATGC CTTCATCGAG TATGAGCATG AACGAGACAT GCACTCCGCT 
TACAAGCACG CAGATGGCAA GAAGATAGAT GGCAGGAGGG TCCTCGTGGA TGTGGAGAGG 
GGCCGGACTG TGAAGGGCTG GAGGCCCCGG CGGCTAGGAG GTGGCCTTGG TGGTACCAGA 
AGAGGTGGGG CAGATGTGAA TATCAGGCAT TCAGGCCGAG ATGACACTTC CCGATATGAT 
GAGAGGCCGG GCCCCTCCCC GCTTCCACAC AGAGACCGGG ACCGGGACCG CGAGCGGGAG 
CGCAGAGAAA GAAGCCGAGA GCGAGACAAG GAGAGAGAAA GGAGACGCTC CCGCTCTCGG 
GACCGGAGGA GGCGCTCTCG GAGTCGAGAC AAGGATGAGC GGCGCCGATC CAGAGAGCGA 
AGCAAGGACA AAGACAGAGA TCGAAAGCGT CGAAGTAGTC GGAGCCGGGA GCGAGCACGC 
AGGGAGCGGG AGCGAAAAGA GGAGCTTCGA GGCGGAGGAG GAGGTGGTGG TGGTGGTGGT 
GGTGGCGGCG GCGGAGGCGG TGGAGGCGAC ATGGCTGAAC CCTCTGAAGC TGGTGATGGA 
GCTCCTGATG ATGGGCCTCC TGGAGAGCTT GGCCCTGAAG GCCCTGATGG CCCTGAGGAG 
AAGGGTCGGG ATCGAGACCG GGAGAGGCGT CGAAGTCACC GAAGTGAGAG GGAACGCCGT 
CGGGACCGAG ACCGTGACCG GGATAGAGAG CACAAGCGTG GGGAGCGGGG CAGTGAGCGG 
GGCAGGGATG AGGCCCGGGG TGGGGGTGGC AGCGGTCAGG ACAATGGGCT GGAAGGGCTA 
GGTAGTGATG GTCGAGACAT GTACATGGAG GCCGAGGGTG GGGATGGGTA CATGGCCCCA 
GAGAACGGAT ATCTGATGGA GGCAGCGCCT GAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006229164.1
CDS	135..1490
Translation	MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKDERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGGGGGGGGGGGGGGGGDMAEPSEAGDGAPDDGPPGELGPEGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDREHKRGERGSERGRDEARGGGGSGQDNGLEGLGSDGRDMYMEAEGGDGYMAPENGYLMEAAPE

Target ORF information:

RefSeq Version	XM_006229102.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus small nuclear ribonucleoprotein U1 subunit 70 (Snrnp70), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006229102.3

ORF Insert Sequence:

ATGACACAGT TTCTGCCTCC CAACCTTCTG GCCCTTTTTG CACCCCGAGA CCCCATCCCA 
TACCTGCCAC CCCTGGAAAA GCTGCCACAT GAAAAACACC ATAACCAACC TTACTGTGGC 
ATTGCACCAT ATATCCGAGA GTTTGAGGAC CCTCGAGATG CCCCTCCTCC AACAAGGGCA 
GAAACCCGGG AAGAACGCAT GGAGAGAAAG AGACGGGAAA AAATTGAACG GCGACAGCAG 
GAAGTGGAGA CAGAGCTGAA AATGTGGGAC CCTCACAATG ATCCCAATGC TCAGGGCGAT 
GCCTTCAAGA CTCTGTTCGT GGCTAGAGTG AACTATGACA CAACAGAATC TAAGCTGCGA 
AGAGAGTTTG AGGTGTACGG ACCCATCAAA AGAATCCACA TGGTCTACAG TAAACGCTCT 
GGGAAACCCC GTGGTTATGC CTTCATCGAG TATGAGCATG AACGAGACAT GCACTCCGCT 
TACAAGCACG CAGATGGCAA GAAGATAGAT GGCAGGAGGG TCCTCGTGGA TGTGGAGAGG 
GGCCGGACTG TGAAGGGCTG GAGGCCCCGG CGGCTAGGAG GTGGCCTTGG TGGTACCAGA 
AGAGGTGGGG CAGATGTGAA TATCAGGCAT TCAGGCCGAG ATGACACTTC CCGATATGAT 
GAGAGGCCGG GCCCCTCCCC GCTTCCACAC AGAGACCGGG ACCGGGACCG CGAGCGGGAG 
CGCAGAGAAA GAAGCCGAGA GCGAGACAAG GAGAGAGAAA GGAGACGCTC CCGCTCTCGG 
GACCGGAGGA GGCGCTCTCG GAGTCGAGAC AAGGATGAGC GGCGCCGATC CAGAGAGCGA 
AGCAAGGACA AAGACAGAGA TCGAAAGCGT CGAAGTAGTC GGAGCCGGGA GCGAGCACGC 
AGGGAGCGGG AGCGAAAAGA GGAGCTTCGA GGCGGAGGAG GAGGTGGTGG TGGTGGTGGT 
GGTGGCGGCG GCGGAGGCGG TGGAGGCGAC ATGGCTGAAC CCTCTGAAGC TGGTGATGGA 
GCTCCTGATG ATGGGCCTCC TGGAGAGCTT GGCCCTGAAG GCCCTGATGG CCCTGAGGAG 
AAGGGTCGGG ATCGAGACCG GGAGAGGCGT CGAAGTCACC GAAGTGAGAG GGAACGCCGT 
CGGGACCGAG ACCGTGACCG GGATAGAGAG CACAAGCGTG GGGAGCGGGG CAGTGAGCGG 
GGCAGGGATG AGGCCCGGGG TGGGGGTGGC AGCGGTCAGG ACAATGGGCT GGAAGGGCTA 
GGTAGTGATG GTCGAGACAT GTACATGGAG GCCGAGGGTG GGGATGGGTA CATGGCCCCA 
GAGAACGGAT ATCTGATGGA GGCAGCGCCT GAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition.
eLife4(2015 Jan)
Kondo Y,Oubridge C,van Roon AM,Nagai K

U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America110(41)16562-7(2013 Oct)
Bai B,Hales CM,Chen PC,Gozal Y,Dammer EB,Fritz JJ,Wang X,Xia Q,Duong DM,Street C,Cantero G,Cheng D,Jones DR,Wu Z,Li Y,Diner I,Heilman CJ,Rees HD,Wu H,Lin L,Szulwach KE,Gearing M,Mufson EJ,Bennett DA,Montine TJ,Seyfried NT,Wingo TS,Sun YE,Jin P,Hanfelt J,Willcock DM,Levey A,Lah JJ,Peng J

The nuclear cap-binding complex interacts with the U4/U6?U5 tri-snRNP and promotes spliceosome assembly in mammalian cells.
RNA (New York, N.Y.)19(8)1054-63(2013 Aug)
Pabis M,Neufeld N,Steiner MC,Bojic T,Shav-Tal Y,Neugebauer KM

A broadly applicable high-throughput screening strategy identifies new regulators of Dlg4 (Psd-95) alternative splicing.
Genome research23(6)998-1007(2013 Jun)
Zheng S,Damoiseaux R,Chen L,Black DL

Structural analyses of the pre-mRNA splicing machinery.
Protein science : a publication of the Protein Society22(6)677-92(2013 Jun)
Zhang L,Li X,Zhao R

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Snrnp70 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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