Vrk3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Vrk3
Entrez Gene ID	361565
Full Name	vaccinia related kinase 3
General protein information	Preferred Names vaccinia related kinase 3 Names inactive serine/threonine-protein kinase VRK3 serine/threonine-protein kinase VRK3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q22

mRNA and Protein(s)

mRNA	Protein	Name
XM_006229096.3	XP_006229158.1	inactive serine/threonine-protein kinase VRK3 isoform X1
NM_001005561.2	NP_001005561.2	inactive serine/threonine-protein kinase VRK3

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	VRK3	XP_541482.3
	VRK3	XP_001115913.1
Rattus norvegicus (Norway rat)	Vrk3	NP_001005561.1
Mus musculus (house mouse)	Vrk3	NP_598706.1
Homo sapiens (human)	VRK3	NP_057524.3
Pan troglodytes (chimpanzee)	VRK3	XP_003339380.1
Xenopus tropicalis (tropical clawed frog)	vrk3	NP_001037922.1
Bos taurus (cattle)	VRK3	NP_001039716.1
Danio rerio (zebrafish)	vrk3	NP_001013586.1

Gene Ontology
Bibliography

Related articles in PubMed

Sensitive detection of idiotypic platelet-reactive alloantibodies by an electrical protein chip.
Quiel A, J?rgen B, Greinacher A, Lassen S, W?rl R, Witt S, Schweder T
Biosensors & bioelectronics36(1)207-11(2012 Jun-Jul)

Proteomic characterization of the human sperm nucleus.
de Mateo S, Castillo J, Estanyol JM, Ballesc? JL, Oliva R
Proteomics11(13)2714-26(2011 Jul)

VRK3-mediated inactivation of ERK signaling in adult and embryonic rodent tissues.
Kang TH, Kim KT
Biochimica et biophysica acta1783(1)49-58(2008 Jan)

Characterization of three paralogous members of the Mammalian vaccinia related kinase family.
Nichols RJ, Traktman P
The Journal of biological chemistry279(9)7934-46(2004 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

various other rodent adult tissues and embryos possess a common signaling mechanism which is involved in an indirect regulation of ERK activity by VRK3-mediated vaccinia H1-related (VHR) phosphatase activity
Title: VRK3-mediated inactivation of ERK signaling in adult and embryonic rodent tissues.

The following Vrk3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Vrk3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa22744	NM_001005561.2 Latest version!	Rattus norvegicus VRK serine/threonine kinase 3 (Vrk3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
ORa22745	XM_006229096.3 Latest version!	Rattus norvegicus vaccinia related kinase 3 (Vrk3), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Vrk3 ( NM_001005561.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001005561.2 Rattus norvegicus VRK serine/threonine kinase 3 (Vrk3), mRNA.

Price & Availability↑

CloneID	ORa22744
Clone ID Related Accession (Same CDS sequence)	NM_001005561.2
Accession Version	NM_001005561.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1389bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-08-28
Organism	Rattus norvegicus(Norway rat)
Product	inactive serine/threonine-protein kinase VRK3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC094894.6. On or before Jun 26, 2015 this sequence version replaced XM_006229095.2, NM_001005561.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: FQ218807.1, BC081928.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACCAGG CCCTGAGTCC ACAAAGCATG ATCTCCTTCT GTCCACTCTG TGGCAAAAGT 
GTCAAAGTAT CATTCAAGTT CTGCCCTTAC TGTGGCGAGG CCCTGCCTGT AGAGGAGGAT 
GGAGGCACCC AGACTGGCAT TACGCCTCTT GTGTCACCCT TTCGAGGCTC CAAGAGAGAC 
CTGAACTCCA GTTCTGAAAC CTCCCCCAAG AAAGTGAAAT GGTCACGCAC TGTCACTTCT 
CTCCCGCTCT CCCTCCACTC TGACTATGAC AGTTCTGGAT CTGATGACAC CTTGAGTTCT 
CCTGACAGAG CCACAGGCAC CCGGAGCAGA TCCCAGACCC CTAAAGGCAG CCCACTTGCC 
AACAGGCTGA GCCCTCGGAC ACTGAAGCGG AGCCGGGTGA CCACCTCACT CCAGGCTCTG 
CCCACAGGGA CAGAGCTGAC AGACCAGAAT GGGAAGCACT GGACACTGGG GACCCTGCAG 
ACCCGGGATG ACCAAGGCAT TCTCTATGCA GCTGAGCCTA CTTCTGCCAT CTCCAGTGAA 
TCAAGGACCC AGAAGTGGAG ATTCTCCCTC AAACTGGACT CCAAAGACGG GCGCCTTTTC 
AATGAGCAGA ACTTCTTTCA GAGAGCAGCC AAGCCTCTGC AAGTGAACAA GTGGAAGAAG 
CGGTGCTTGA CCCCGCTCCT GGCCATCCCC ACCTGCATCG GCTTTGGCGT TCACCAGGAC 
AAGTACAGGT TCCTAGTGTT CCCCAGCCTG GGGAGGAGCC TTCAGTCAGC CCTGGACGAC 
AACCCGAAGC ATGTGGTATC CGAGAGATGT ATGCTGCAGG TGGCCTGCAG GCTGCTGGAT 
GCTCTGGAGT ATCTCCATGA ACACGAGTAT GTTCACGGGA ACCTGACCAC TGAGAATGTC 
TTTGTGAATC CAGAGGACCT GAGCCAGGTG ACCCTGGTGG GCTATGGCTT CACCTACCGA 
TACTGCCCAG GTGGCAAGCA CGTGGCCTAT AAAGAAGGCA GCAGGAGTCT ACACGATGGG 
GACCTGGAGT TCATTAGCAT GGACGTGCAC AAGGGATGCG GGCCCTCCCG CCGCAGCGAT 
CTCCAGACCT TGGGCTACTG TATGCTCAAG TGGCTTTATG GGTCCCTGCC ATGGACAAAC 
TGCCTTCCCA ACACTGAAGA GATAACTAAG CAGAAGCAGA AGTATCAGGA CAACCCTGAG 
CCCCTGGTGG GACTGTGTGG CCGCTGGAAC AAGACCTCAG AGACCTTGCG GGAGTACCTG 
AAGGTGGTGA TGGCCCTTGA TTACGAGGAG AAGCCGCCCT ATGCCACGCT GAGGAACAAT 
CTAGAAGTTC TGCTGCAGAA TATGCGGGTG TCACCCTATG ACCCCCTGGA CCTCCAGATG 
GTGCCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001005561.2
CDS	69..1457
Translation	MDQALSPQSMISFCPLCGKSVKVSFKFCPYCGEALPVEEDGGTQTGITPLVSPFRGSKRDLNSSSETSPKKVKWSRTVTSLPLSLHSDYDSSGSDDTLSSPDRATGTRSRSQTPKGSPLANRLSPRTLKRSRVTTSLQALPTGTELTDQNGKHWTLGTLQTRDDQGILYAAEPTSAISSESRTQKWRFSLKLDSKDGRLFNEQNFFQRAAKPLQVNKWKKRCLTPLLAIPTCIGFGVHQDKYRFLVFPSLGRSLQSALDDNPKHVVSERCMLQVACRLLDALEYLHEHEYVHGNLTTENVFVNPEDLSQVTLVGYGFTYRYCPGGKHVAYKEGSRSLHDGDLEFISMDVHKGCGPSRRSDLQTLGYCMLKWLYGSLPWTNCLPNTEEITKQKQKYQDNPEPLVGLCGRWNKTSETLREYLKVVMALDYEEKPPYATLRNNLEVLLQNMRVSPYDPLDLQMVP

Target ORF information:

RefSeq Version	NM_001005561.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus VRK serine/threonine kinase 3 (Vrk3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001005561.2

ORF Insert Sequence:

ATGGACCAGG CCCTGAGTCC ACAAAGCATG ATCTCCTTCT GTCCACTCTG TGGCAAAAGT 
GTCAAAGTAT CATTCAAGTT CTGCCCTTAC TGTGGCGAGG CCCTGCCTGT AGAGGAGGAT 
GGAGGCACCC AGACTGGCAT TACGCCTCTT GTGTCACCCT TTCGAGGCTC CAAGAGAGAC 
CTGAACTCCA GTTCTGAAAC CTCCCCCAAG AAAGTGAAAT GGTCACGCAC TGTCACTTCT 
CTCCCGCTCT CCCTCCACTC TGACTATGAC AGTTCTGGAT CTGATGACAC CTTGAGTTCT 
CCTGACAGAG CCACAGGCAC CCGGAGCAGA TCCCAGACCC CTAAAGGCAG CCCACTTGCC 
AACAGGCTGA GCCCTCGGAC ACTGAAGCGG AGCCGGGTGA CCACCTCACT CCAGGCTCTG 
CCCACAGGGA CAGAGCTGAC AGACCAGAAT GGGAAGCACT GGACACTGGG GACCCTGCAG 
ACCCGGGATG ACCAAGGCAT TCTCTATGCA GCTGAGCCTA CTTCTGCCAT CTCCAGTGAA 
TCAAGGACCC AGAAGTGGAG ATTCTCCCTC AAACTGGACT CCAAAGACGG GCGCCTTTTC 
AATGAGCAGA ACTTCTTTCA GAGAGCAGCC AAGCCTCTGC AAGTGAACAA GTGGAAGAAG 
CGGTGCTTGA CCCCGCTCCT GGCCATCCCC ACCTGCATCG GCTTTGGCGT TCACCAGGAC 
AAGTACAGGT TCCTAGTGTT CCCCAGCCTG GGGAGGAGCC TTCAGTCAGC CCTGGACGAC 
AACCCGAAGC ATGTGGTATC CGAGAGATGT ATGCTGCAGG TGGCCTGCAG GCTGCTGGAT 
GCTCTGGAGT ATCTCCATGA ACACGAGTAT GTTCACGGGA ACCTGACCAC TGAGAATGTC 
TTTGTGAATC CAGAGGACCT GAGCCAGGTG ACCCTGGTGG GCTATGGCTT CACCTACCGA 
TACTGCCCAG GTGGCAAGCA CGTGGCCTAT AAAGAAGGCA GCAGGAGTCT ACACGATGGG 
GACCTGGAGT TCATTAGCAT GGACGTGCAC AAGGGATGCG GGCCCTCCCG CCGCAGCGAT 
CTCCAGACCT TGGGCTACTG TATGCTCAAG TGGCTTTATG GGTCCCTGCC ATGGACAAAC 
TGCCTTCCCA ACACTGAAGA GATAACTAAG CAGAAGCAGA AGTATCAGGA CAACCCTGAG 
CCCCTGGTGG GACTGTGTGG CCGCTGGAAC AAGACCTCAG AGACCTTGCG GGAGTACCTG 
AAGGTGGTGA TGGCCCTTGA TTACGAGGAG AAGCCGCCCT ATGCCACGCT GAGGAACAAT 
CTAGAAGTTC TGCTGCAGAA TATGCGGGTG TCACCCTATG ACCCCCTGGA CCTCCAGATG 
GTGCCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Vrk3 ( XM_006229096.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006229158.1 Rattus norvegicus vaccinia related kinase 3 (Vrk3), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa22745
Clone ID Related Accession (Same CDS sequence)	XM_006229096.3
Accession Version	XM_006229096.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1335bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	inactive serine/threonine-protein kinase VRK3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006229096.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCAGG CCCTGAGTCC ACAAAGCATG ATCTCCTTCT GTCCACTCTG TGGCAAAAGT 
GTCAAAGTAT CATTCAAGTT CTGCCCTTAC TGTGGCGAGG CCCTGCCTGT AGAGGAGGAT 
GGAGGCACCC AGACTGGCAT TACGCCTCTT GTGTCACCCT TTCGAGGCTC CAAGAGAGAC 
CTGAACTCCA GTTCTGAAAC CTCCCCCAAG AAAGTGAAAT GGTCACGCAC TGTCACTTCT 
CTCCCGCTCT CCCTCCACTC TGACTATGAC AGTTCTGGAT CTGATGACAC CTTGAGTTCT 
CCTGACAGAG CCACAGGCAC CCGGAGCAGA TCCCAGACCC CTAAAGGCAG CCCACTTGCC 
AACAGGCTGA GCCCTCGGAC ACTGAAGCGG AGCCGGGTGA CCACCTCACT CCAGGCTCTG 
CCCACAGGGA CAGAGCTGAC AGACCAGAAT GGGAAGCACT GGACACTGGG GACCCTGCAG 
ACCCGGGATG ACCAAGGCAT TCTCTATGCA GCTGAGCCTA CTTCTGCCAT CTCCAGTGAA 
TCAAGGACCC AGAAGTGGAG ATTCTCCCTC AAACTGGACT CCAAAGACGG GCGCCTTTTC 
AATGAGCAGA ACTTCTTTCA GAGAGCAGCC AAGCCTCTGC AAGTGAACAA GTGGAAGAAG 
CGGTGCTTGA CCCCGCTCCT GGCCATCCCC ACCTGCATCG GCTTTGGCGT TCACCAGGAC 
AAGTACAGGT TCCTAGTGTT CCCCAGCCTG GGGAGGAGCC TTCAGTCAGC CCTGGACGAC 
AACCCGAAGC ATGTGGTATC CGAGAGATGT ATGCTGCAGG TGGCCTGCAG GCTGCTGGAT 
GCTCTGGAGT ATCTCCATGA ACACGAGTAT GTTCACGGGA ACCTGACCAC TGAGAATGTC 
TTTGTGAATC CAGAGGACCT GAGCCAGGTG ACCCTGGTGG GCTATGGCTT CACCTACCGA 
TACTGCCCAG GTGGCAAGCA CGTGGCCTAT AAAGAAGGCA GCAGGAGTCT ACACGATGGG 
GACCTGGAGT TCATTAGCAT GGACGTGCAC AAGGGATGCG GGCCCTCCCG CCGCAGCGAT 
CTCCAGACCT TGGGCTACTG TATGCTCAAG TGGCTTTATG GGTCCCTGCC ATGGACAAAC 
TGCCTTCCCA ACACTGAAGA GATAACTAAG CAGAAGCAGA AGTATCAGGA CAACCCTGAG 
CCCCTGGTGG GACTGTGTGG CCGCTGGAAC AAGACCTCAG TAACAGGGTT ACAACCACAT 
ACACAATTCT TGAGTTGTTT GGAGCTGGGA ATGGATTCCA GGGCTGGTGC GTGCCAGGCA 
AGTGCTCACC ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006229158.1
CDS	124..1458
Translation	MDQALSPQSMISFCPLCGKSVKVSFKFCPYCGEALPVEEDGGTQTGITPLVSPFRGSKRDLNSSSETSPKKVKWSRTVTSLPLSLHSDYDSSGSDDTLSSPDRATGTRSRSQTPKGSPLANRLSPRTLKRSRVTTSLQALPTGTELTDQNGKHWTLGTLQTRDDQGILYAAEPTSAISSESRTQKWRFSLKLDSKDGRLFNEQNFFQRAAKPLQVNKWKKRCLTPLLAIPTCIGFGVHQDKYRFLVFPSLGRSLQSALDDNPKHVVSERCMLQVACRLLDALEYLHEHEYVHGNLTTENVFVNPEDLSQVTLVGYGFTYRYCPGGKHVAYKEGSRSLHDGDLEFISMDVHKGCGPSRRSDLQTLGYCMLKWLYGSLPWTNCLPNTEEITKQKQKYQDNPEPLVGLCGRWNKTSVTGLQPHTQFLSCLELGMDSRAGACQASAHH

Target ORF information:

RefSeq Version	XM_006229096.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus vaccinia related kinase 3 (Vrk3), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006229096.3

ORF Insert Sequence:

ATGGACCAGG CCCTGAGTCC ACAAAGCATG ATCTCCTTCT GTCCACTCTG TGGCAAAAGT 
GTCAAAGTAT CATTCAAGTT CTGCCCTTAC TGTGGCGAGG CCCTGCCTGT AGAGGAGGAT 
GGAGGCACCC AGACTGGCAT TACGCCTCTT GTGTCACCCT TTCGAGGCTC CAAGAGAGAC 
CTGAACTCCA GTTCTGAAAC CTCCCCCAAG AAAGTGAAAT GGTCACGCAC TGTCACTTCT 
CTCCCGCTCT CCCTCCACTC TGACTATGAC AGTTCTGGAT CTGATGACAC CTTGAGTTCT 
CCTGACAGAG CCACAGGCAC CCGGAGCAGA TCCCAGACCC CTAAAGGCAG CCCACTTGCC 
AACAGGCTGA GCCCTCGGAC ACTGAAGCGG AGCCGGGTGA CCACCTCACT CCAGGCTCTG 
CCCACAGGGA CAGAGCTGAC AGACCAGAAT GGGAAGCACT GGACACTGGG GACCCTGCAG 
ACCCGGGATG ACCAAGGCAT TCTCTATGCA GCTGAGCCTA CTTCTGCCAT CTCCAGTGAA 
TCAAGGACCC AGAAGTGGAG ATTCTCCCTC AAACTGGACT CCAAAGACGG GCGCCTTTTC 
AATGAGCAGA ACTTCTTTCA GAGAGCAGCC AAGCCTCTGC AAGTGAACAA GTGGAAGAAG 
CGGTGCTTGA CCCCGCTCCT GGCCATCCCC ACCTGCATCG GCTTTGGCGT TCACCAGGAC 
AAGTACAGGT TCCTAGTGTT CCCCAGCCTG GGGAGGAGCC TTCAGTCAGC CCTGGACGAC 
AACCCGAAGC ATGTGGTATC CGAGAGATGT ATGCTGCAGG TGGCCTGCAG GCTGCTGGAT 
GCTCTGGAGT ATCTCCATGA ACACGAGTAT GTTCACGGGA ACCTGACCAC TGAGAATGTC 
TTTGTGAATC CAGAGGACCT GAGCCAGGTG ACCCTGGTGG GCTATGGCTT CACCTACCGA 
TACTGCCCAG GTGGCAAGCA CGTGGCCTAT AAAGAAGGCA GCAGGAGTCT ACACGATGGG 
GACCTGGAGT TCATTAGCAT GGACGTGCAC AAGGGATGCG GGCCCTCCCG CCGCAGCGAT 
CTCCAGACCT TGGGCTACTG TATGCTCAAG TGGCTTTATG GGTCCCTGCC ATGGACAAAC 
TGCCTTCCCA ACACTGAAGA GATAACTAAG CAGAAGCAGA AGTATCAGGA CAACCCTGAG 
CCCCTGGTGG GACTGTGTGG CCGCTGGAAC AAGACCTCAG TAACAGGGTT ACAACCACAT 
ACACAATTCT TGAGTTGTTT GGAGCTGGGA ATGGATTCCA GGGCTGGTGC GTGCCAGGCA 
AGTGCTCACC ACTGA