Vasp cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Vasp
Entrez Gene ID	361517
Full Name	vasodilator-stimulated phosphoprotein
General protein information	Preferred Names vasodilator-stimulated phosphoprotein Names vasodilator-stimulated phosphoprotein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q21

mRNA and Protein(s)

mRNA	Protein	Name
XM_017589350.1	XP_017444839.1	vasodilator-stimulated phosphoprotein isoform X1
NM_001108475.2	NP_001101945.2	vasodilator-stimulated phosphoprotein

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	VASP	NP_001003256.1
Mus musculus (house mouse)	Vasp	NP_001268951.1
	LOC716022	XP_001106536.2
Homo sapiens (human)	VASP	NP_003361.1
Bos taurus (cattle)	VASP	NP_001033199.1
Rattus norvegicus (Norway rat)	Vasp	NP_001101945.2

Gene Ontology
Bibliography

Related articles in PubMed

Triiodothyronine Potentiates Vasorelaxation via PKG/VASP Signaling in Vascular Smooth Muscle Cells.
Samuel S, Zhang K, Tang YD, Gerdes AM, Carrillo-Sepulveda MA
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology41(5)1894-1904(2017)

Arp2/3 and VASP Are Essential for Fear Memory Formation in Lateral Amygdala.
Basu S, Kustanovich I, Lamprecht R
eNeuro3(6)(2016 Nov-Dec)

Matrix Metalloproteinase 9 and Vasodilator-Stimulated Phosphoprotein Related to Acute Kidney Injury in Severe Acute Pancreatitis Rats.
Li H, Liu J, Wang W, Zhang Z, Li D, Lin K, Chen Z, Lin W
Digestive diseases and sciences60(12)3647-55(2015 Dec)

Selectivity in subunit composition of Ena/VASP tetramers.
Riquelme DN, Meyer AS, Barzik M, Keating A, Gertler FB
Bioscience reports35(5)(2015 Jul)

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Guo Z, Neilson LJ, Zhong H, Murray PS, Zanivan S, Zaidel-Bar R
Science signaling7(354)rs7(2014 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

findings have uncovered a PKG/VASP signaling pathway in Vascular Smooth Muscle Cells as a key molecular mechanism underlying T3-induced vascular relaxation.
Title: Triiodothyronine Potentiates Vasorelaxation via PKG/VASP Signaling in Vascular Smooth Muscle Cells.

Study showed that Arp2/3 and VASP, but not formins, are needed in lateral amygdala for long-term, but not short-term, fear memory formation. Results suggest a mechanism whereby actin cytoskeleton remodeling leads to changes in neuronal morphogenesis needed for memory consolidation.
Title: Arp2/3 and VASP Are Essential for Fear Memory Formation in Lateral Amygdala.

In the presence of acute kidney injury in severe, acute pancreatitis, the renal expression of MMP-9 and VASP is related to damage of endothelial cells in capillaries, which reached a maximum at 24 h and declined afterwards.
Title: Matrix Metalloproteinase 9 and Vasodilator-Stimulated Phosphoprotein Related to Acute Kidney Injury in Severe Acute Pancreatitis Rats.

Co-expression of VASP increased the ability of Mena and EVL to form mixed oligomers.
Title: Selectivity in subunit composition of Ena/VASP tetramers.

These results suggest that diminished VASP expression and/or Ser157 phosphorylation mediates endothelial changes associated with hypertension and exercise may normalize these changes.
Title: Hypertension alters phosphorylation of VASP in brain endothelial cells.

The following Vasp gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Vasp cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa07433	NM_001108475.2 Latest version!	Rattus norvegicus vasodilator-stimulated phosphoprotein (Vasp), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
ORa56680	XM_017589350.1 Latest version!	Rattus norvegicus vasodilator-stimulated phosphoprotein (Vasp), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Vasp ( NM_001108475.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101945.2 Rattus norvegicus vasodilator-stimulated phosphoprotein (Vasp), mRNA.

Price & Availability↑

CloneID	ORa07433
Clone ID Related Accession (Same CDS sequence)	NM_001108475.2
Accession Version	NM_001108475.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1131bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-01
Organism	Rattus norvegicus(Norway rat)
Product	vasodilator-stimulated phosphoprotein
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC168841.1. On Sep 4, 2008 this sequence version replaced NM_001108475.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC168841.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2689594, SAMN00632252 [ECO:0000350] ##Evidence-Data-END##

ATGAGCAACG AGACGGTCAT TTGTTCCAGC CGGGCTACTG TGATGCTTTA CGATGACAGC 
AACAAACGAT GGCTTCCTGC TGGCACCGGT CCCCAGGCCT TTAGCCGCGT CCAGATCTAC 
CACAACCCCA CTGCTAACTC TTTCCGAGTT GTTGGCCGCA AGCTGCAGCC TGACCAGCAG 
GTGGTTATCA ACTGTGCCAT CATTCGAGGT GTCAAGTACA ATCAGGCCAC TCCCATATTC 
CACCAGTGGC GTGATGCCCG CCAGGTCTGG GGCCTCAACT TCGGCAGCAA GGAGGACGCT 
GCGCAGTTTG CGATCGGCAT GGCCAATGCC CTGGAGGCCT TGGAAGGAGG TGGGCCTCCC 
CCTGCCCCAG CACCCCCTGC CTGGTCTACC CAGAATGGCC CCTCCCCAGA GGAGCTGGAA 
CAACAGAAAA GGCAGCCTGA ACATTTGGAG CGCCGGGTCT CCAATGCAGG AGGCCCACCT 
GCTCCCCCAG CTGGGGGCCC ACCTCCACCT CCAGGACCTC CCCCTCCTCC GGGTCCCCCC 
CCACCCCCAG GTCTGCCCCC CTCAGGGGTA TCTGGGGCAG GTCATGGAAC AGGTGTAGCC 
CCACCCCCTG CACCCCCACT CCCTACAGCA CAGGGCCCCA GTAGTGGGGG TTCCGGGGCC 
CCAGGCCTGG CCGCTGCCAT TGCTGGAGCC AAACTCAGGA AAGTGAGCAA GGAGGAGGCC 
TCTGGGGGGC CCCTGGCCCC CAAAGCTGAG AATAGTCGAG GCACTGGTGG GGGGCTTATG 
GAAGAGATGA ACGCCATGCT GGCCCGGAGA AGGAAAGCCA CACAGGTTGG GGAGAAGCCC 
CCCAAAGACG AGTCAGCCAG TCAGGAGGAG TCAGAGGCCC GAATCCCTGC CCAAAGTGAA 
CCTGTGCGAA GACCCTGGGA GAAGAACAGC ACAACCTTGC CAAGGATGAA GTCATCCTCT 
TCTGTGACTA CCTCCGAGGC CCACCCCTCT GTGCCCAGCT CCAGTGATGA CTCCGACTTG 
GAGAGGGTGA AGCAGGAGCT TGTGGAAGAG GTGCGGAAGG AGCTACAGAA AATGAAAGAG 
GAAATAATCG AAGTCTTTGT CCAGGAGCTG AGGAAGCGGG GTTCTCCTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101945.2
CDS	179..1309
Translation	MSNETVICSSRATVMLYDDSNKRWLPAGTGPQAFSRVQIYHNPTANSFRVVGRKLQPDQQVVINCAIIRGVKYNQATPIFHQWRDARQVWGLNFGSKEDAAQFAIGMANALEALEGGGPPPAPAPPAWSTQNGPSPEELEQQKRQPEHLERRVSNAGGPPAPPAGGPPPPPGPPPPPGPPPPPGLPPSGVSGAGHGTGVAPPPAPPLPTAQGPSSGGSGAPGLAAAIAGAKLRKVSKEEASGGPLAPKAENSRGTGGGLMEEMNAMLARRRKATQVGEKPPKDESASQEESEARIPAQSEPVRRPWEKNSTTLPRMKSSSSVTTSEAHPSVPSSSDDSDLERVKQELVEEVRKELQKMKEEIIEVFVQELRKRGSP

Target ORF information:

RefSeq Version	NM_001108475.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus vasodilator-stimulated phosphoprotein (Vasp), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108475.2

ORF Insert Sequence:

ATGAGCAACG AGACGGTCAT TTGTTCCAGC CGGGCTACTG TGATGCTTTA CGATGACAGC 
AACAAACGAT GGCTTCCTGC TGGCACCGGT CCCCAGGCCT TTAGCCGCGT CCAGATCTAC 
CACAACCCCA CTGCTAACTC TTTCCGAGTT GTTGGCCGCA AGCTGCAGCC TGACCAGCAG 
GTGGTTATCA ACTGTGCCAT CATTCGAGGT GTCAAGTACA ATCAGGCCAC TCCCATATTC 
CACCAGTGGC GTGATGCCCG CCAGGTCTGG GGCCTCAACT TCGGCAGCAA GGAGGACGCT 
GCGCAGTTTG CGATCGGCAT GGCCAATGCC CTGGAGGCCT TGGAAGGAGG TGGGCCTCCC 
CCTGCCCCAG CACCCCCTGC CTGGTCTACC CAGAATGGCC CCTCCCCAGA GGAGCTGGAA 
CAACAGAAAA GGCAGCCTGA ACATTTGGAG CGCCGGGTCT CCAATGCAGG AGGCCCACCT 
GCTCCCCCAG CTGGGGGCCC ACCTCCACCT CCAGGACCTC CCCCTCCTCC GGGTCCCCCC 
CCACCCCCAG GTCTGCCCCC CTCAGGGGTA TCTGGGGCAG GTCATGGAAC AGGTGTAGCC 
CCACCCCCTG CACCCCCACT CCCTACAGCA CAGGGCCCCA GTAGTGGGGG TTCCGGGGCC 
CCAGGCCTGG CCGCTGCCAT TGCTGGAGCC AAACTCAGGA AAGTGAGCAA GGAGGAGGCC 
TCTGGGGGGC CCCTGGCCCC CAAAGCTGAG AATAGTCGAG GCACTGGTGG GGGGCTTATG 
GAAGAGATGA ACGCCATGCT GGCCCGGAGA AGGAAAGCCA CACAGGTTGG GGAGAAGCCC 
CCCAAAGACG AGTCAGCCAG TCAGGAGGAG TCAGAGGCCC GAATCCCTGC CCAAAGTGAA 
CCTGTGCGAA GACCCTGGGA GAAGAACAGC ACAACCTTGC CAAGGATGAA GTCATCCTCT 
TCTGTGACTA CCTCCGAGGC CCACCCCTCT GTGCCCAGCT CCAGTGATGA CTCCGACTTG 
GAGAGGGTGA AGCAGGAGCT TGTGGAAGAG GTGCGGAAGG AGCTACAGAA AATGAAAGAG 
GAAATAATCG AAGTCTTTGT CCAGGAGCTG AGGAAGCGGG GTTCTCCTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Vasp ( XM_017589350.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017444839.1 Rattus norvegicus vasodilator-stimulated phosphoprotein (Vasp), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa56680
Clone ID Related Accession (Same CDS sequence)	XM_017589350.1
Accession Version	XM_017589350.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1146bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	vasodilator-stimulated phosphoprotein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAACTGCA ACGAGACGGT CATTTGTTCC AGCCGGGCTA CTGTGATGCT TTACGATGAC 
AGCAACAAAC GATGGCTTCC TGCTGGCACC GGTCCCCAGG CCTTTAGCCG CGTCCAGATC 
TACCACAACC CCACTGCTAA CTCTTTCCGA GTTGTTGGCC GCAAGCTGCA GCCTGACCAG 
CAGGTGGTTA TCAACTGTGC CATCATTCGA GGTGTCAAGT ACAATCAGGC CACTCCCATA 
TTCCACCAGT GGCGTGATGC CCGCCAGGTC TGGGGCCTCA ACTTCGGCAG CAAGGAGGAC 
GCTGCGCAGT TTGCGATCGG CATGGCCAAT GCCCTGGAGG CCTTGGAAGG AGGTGGGCCT 
CCCCCTGCCC CAGCACCCCC TGCCTGGTCT ACCCAGAATG GCCCCTCCCC AGAGGAGCTG 
GAACAACAGA AAAGGCAGCC TGAACATTTG GAGCGCCGGG TCTCCAATGC AGGAGGCCCA 
CCTGCTCCCC CAGCTGGGGG CCCACCTCCA CCTCCAGGAC CTCCCCCTCC TCCGGGTCCC 
CCCCCACCCC CAGGTCTGCC CCCCTCAGGG GTATCTGGGG CAGGTCATGG AACAGGTGTA 
GCCCCACCCC CTGCACCCCC ACTCCCTACA GCACAGGGCC CCAGTAGTGG GGGTTCCGGG 
GCCCCAGGCC TGGCCGCTGC CATTGCTGGA GCCAAACTCA GGAAAGTGAG CAAGCAGGAG 
GAGGCCTCTG GGGGGCCCCT GGCCCCCAAA GCTGAGAATA GTCGAGGCAC TGGTGGGGGG 
CTTATGGAAG AGATGAACGC CATGCTGGCC CGGAGAAGGA AAGCCACACA GGTTGGGGAG 
AAGCCCCCCA AAGACGAGTC AGCCAGTGAG GAGTCAGAGG CCCGAATCCC TGCCCAAAGT 
GAACCTGTGC GAAGACCCTG GGAGAAGAAC AGTACCTCAC TCCTGTCCGA CTCTTCCAGG 
ATGAAGTCAT CCTCTTCTGT GACTACCTCC GAGGCCCACC CCTCTGTGCC CAGCTCCAGT 
GATGACTCCG ACTTGGAGAG GGTGAAGCAG GAGCTTGTGG AAGAGGTGCG GAAGGAGCTA 
CAGAAAATGA AAGAGGAAAT AATCGAAGTC TTTGTCCAGG AGCTGAGGAA GCGGGGTTCT 
CCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017444839.1
CDS	313..1458
Translation	MNCNETVICSSRATVMLYDDSNKRWLPAGTGPQAFSRVQIYHNPTANSFRVVGRKLQPDQQVVINCAIIRGVKYNQATPIFHQWRDARQVWGLNFGSKEDAAQFAIGMANALEALEGGGPPPAPAPPAWSTQNGPSPEELEQQKRQPEHLERRVSNAGGPPAPPAGGPPPPPGPPPPPGPPPPPGLPPSGVSGAGHGTGVAPPPAPPLPTAQGPSSGGSGAPGLAAAIAGAKLRKVSKQEEASGGPLAPKAENSRGTGGGLMEEMNAMLARRRKATQVGEKPPKDESASEESEARIPAQSEPVRRPWEKNSTSLLSDSSRMKSSSSVTTSEAHPSVPSSSDDSDLERVKQELVEEVRKELQKMKEEIIEVFVQELRKRGSP

Target ORF information:

RefSeq Version	XM_017589350.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus vasodilator-stimulated phosphoprotein (Vasp), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017589350.1

ORF Insert Sequence:

ATGAACTGCA ACGAGACGGT CATTTGTTCC AGCCGGGCTA CTGTGATGCT TTACGATGAC 
AGCAACAAAC GATGGCTTCC TGCTGGCACC GGTCCCCAGG CCTTTAGCCG CGTCCAGATC 
TACCACAACC CCACTGCTAA CTCTTTCCGA GTTGTTGGCC GCAAGCTGCA GCCTGACCAG 
CAGGTGGTTA TCAACTGTGC CATCATTCGA GGTGTCAAGT ACAATCAGGC CACTCCCATA 
TTCCACCAGT GGCGTGATGC CCGCCAGGTC TGGGGCCTCA ACTTCGGCAG CAAGGAGGAC 
GCTGCGCAGT TTGCGATCGG CATGGCCAAT GCCCTGGAGG CCTTGGAAGG AGGTGGGCCT 
CCCCCTGCCC CAGCACCCCC TGCCTGGTCT ACCCAGAATG GCCCCTCCCC AGAGGAGCTG 
GAACAACAGA AAAGGCAGCC TGAACATTTG GAGCGCCGGG TCTCCAATGC AGGAGGCCCA 
CCTGCTCCCC CAGCTGGGGG CCCACCTCCA CCTCCAGGAC CTCCCCCTCC TCCGGGTCCC 
CCCCCACCCC CAGGTCTGCC CCCCTCAGGG GTATCTGGGG CAGGTCATGG AACAGGTGTA 
GCCCCACCCC CTGCACCCCC ACTCCCTACA GCACAGGGCC CCAGTAGTGG GGGTTCCGGG 
GCCCCAGGCC TGGCCGCTGC CATTGCTGGA GCCAAACTCA GGAAAGTGAG CAAGCAGGAG 
GAGGCCTCTG GGGGGCCCCT GGCCCCCAAA GCTGAGAATA GTCGAGGCAC TGGTGGGGGG 
CTTATGGAAG AGATGAACGC CATGCTGGCC CGGAGAAGGA AAGCCACACA GGTTGGGGAG 
AAGCCCCCCA AAGACGAGTC AGCCAGTGAG GAGTCAGAGG CCCGAATCCC TGCCCAAAGT 
GAACCTGTGC GAAGACCCTG GGAGAAGAAC AGTACCTCAC TCCTGTCCGA CTCTTCCAGG 
ATGAAGTCAT CCTCTTCTGT GACTACCTCC GAGGCCCACC CCTCTGTGCC CAGCTCCAGT 
GATGACTCCG ACTTGGAGAG GGTGAAGCAG GAGCTTGTGG AAGAGGTGCG GAAGGAGCTA 
CAGAAAATGA AAGAGGAAAT AATCGAAGTC TTTGTCCAGG AGCTGAGGAA GCGGGGTTCT 
CCTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Triiodothyronine Potentiates Vasorelaxation via PKG/VASP Signaling in Vascular Smooth Muscle Cells.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology41(5)1894-1904(2017)
Samuel S,Zhang K,Tang YD,Gerdes AM,Carrillo-Sepulveda MA

Arp2/3 and VASP Are Essential for Fear Memory Formation in Lateral Amygdala.
eNeuro3(6)(2016 Nov-Dec)
Basu S,Kustanovich I,Lamprecht R

Matrix Metalloproteinase 9 and Vasodilator-Stimulated Phosphoprotein Related to Acute Kidney Injury in Severe Acute Pancreatitis Rats.
Digestive diseases and sciences60(12)3647-55(2015 Dec)
Li H,Liu J,Wang W,Zhang Z,Li D,Lin K,Chen Z,Lin W

Selectivity in subunit composition of Ena/VASP tetramers.
Bioscience reports35(5)(2015 Jul)
Riquelme DN,Meyer AS,Barzik M,Keating A,Gertler FB

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Science signaling7(354)rs7(2014 Dec)
Guo Z,Neilson LJ,Zhong H,Murray PS,Zanivan S,Zaidel-Bar R

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Vasp cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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