Fech cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fech
Entrez Gene ID	361338
Full Name	ferrochelatase
General protein information	Preferred Names ferrochelatase Names ferrochelatase, mitochondrial
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 18 Map Location: 18q12.1

mRNA and Protein(s)

mRNA	Protein	Name
XM_006254850.3	XP_006254912.1	ferrochelatase, mitochondrial isoform X1
NM_001108434.1	NP_001101904.1	ferrochelatase, mitochondrial

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	FECH	NP_989527.1
Kluyveromyces lactis	KLLA0F20141g	XP_455984.1
Eremothecium gossypii	AGOS_AGR272W	NP_986938.1
Schizosaccharomyces pombe (fission yeast)	hem15	NP_587720.1
Xenopus tropicalis (tropical clawed frog)	fech	XP_002934473.1
	FECH	XP_002800996.1
Canis lupus familiaris (dog)	FECH	XP_852936.1
Saccharomyces cerevisiae (baker's yeast)	HEM15	NP_014819.3
Neurospora crassa	NCU08291	XP_962504.1
Oryza sativa (rice)	Os05g0361200	NP_001055309.1
Homo sapiens (human)	FECH	NP_000131.2
Pan troglodytes (chimpanzee)	FECH	NP_001033101.1
Mus musculus (house mouse)	Fech	NP_032024.2
Rattus norvegicus (Norway rat)	Fech	NP_001101904.1
Danio rerio (zebrafish)	fech	NP_571706.1
Drosophila melanogaster (fruit fly)	ferrochelatase	NP_524613.1
Arabidopsis thaliana (thale cress)	FC2	NP_001189639.1
Bos taurus (cattle)	FECH	NP_776479.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003719	XP_310249.3
Magnaporthe oryzae (rice blast fungus)	MGG_15723	XP_003714486.1

Gene Ontology
Bibliography

Related articles in PubMed

Erythropoietic protoporphyria a clinical and molecular study from Lebanon: Ferrochelatase a potential tumor suppressor gene in colon cancer.
Kadara H, Nemer G, Safi R, Rebeiz N, Daou L, Delbani D, Btadini W, Abbas O, Tofaili M, Bitar F, Kibbi AG, Shimomura Y, Kurban M
Clinical genetics92(5)495-502(2017 Nov)

Synthesis, delivery and regulation of eukaryotic heme and Fe-S cluster cofactors.
Barupala DP, Dzul SP, Riggs-Gelasco PJ, Stemmler TL
Archives of biochemistry and biophysics59260-75(2016 Feb)

Incomplete erythropoietic protoporphyria caused by a splice site modulator homozygous IVS3-48C polymorphism in the ferrochelatase gene.
Mizawa M, Makino T, Nakano H, Sawamura D, Shimizu T
The British journal of dermatology174(1)172-5(2016 Jan)

A Novel Mutation in the FECH Gene in a Czech Family with Erythropoietic Protoporphyria and a Population Study of IVS3-48C Variant Contributing to the Disease.
Farrag MS, Ku?erov? J, ?lachtov? L, ?eda O, ?perl J, Mart?sek P
Folia biologica61(6)227-32(2015)

HRG1 is essential for heme transport from the phagolysosome of macrophages during erythrophagocytosis.
White C, Yuan X, Schmidt PJ, Bresciani E, Samuel TK, Campagna D, Hall C, Bishop K, Calicchio ML, Lapierre A, Ward DM, Liu P, Fleming MD, Hamza I
Cell metabolism17(2)261-70(2013 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Fech gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fech cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa07316	NM_001108434.1 Latest version!	Rattus norvegicus ferrochelatase (Fech), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
ORa38451	XM_006254850.3 Latest version!	Rattus norvegicus ferrochelatase (Fech), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fech ( NM_001108434.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101904.1 Rattus norvegicus ferrochelatase (Fech), mRNA.

Price & Availability↑

CloneID	ORa07316
Clone ID Related Accession (Same CDS sequence)	NM_001108434.1
Accession Version	NM_001108434.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1269bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-26
Organism	Rattus norvegicus(Norway rat)
Product	ferrochelatase, mitochondrial
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473971.1. On or before Oct 4, 2007 this sequence version replaced XM_001060349.1, XM_341622.3, XM_001060280.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01906349 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END##

ATGCTTTCGG CCGGCGCCAA CATGGCTGCG GCCCTGCGGG CTGCGGGCGC TCTGTTCCGC 
GAGCCGCTGG TGTATGGCAG CTCGAGGGCC TGTCAGCCAT GGAGGTGCCA ATCGGGTCCA 
GCAGTGGTGG CCACTACGGA GAAAGCGCAT CATGCCAAAA CCACAAAACC ACAAGCTCAA 
CCAGAAAGGA GGAAGCCCAA AACGGGCATA TTAATGTTAA ACATGGGAGG CCCCGAAACC 
CTTGGAGAAG TTCAAGACTT CCTTCAGAGG CTCTTCCTGG ACCGAGACCT CATGACCCTT 
CCCATTCAAA ATAAGCTGGC ACCATTCATC GCCAAACGCC GAACCCCCAA AATTCAAGAG 
CAGTATCGCA GAATCGGAGG TGGATCCCCC ATCAAGATGT GGACTTCCAA GCAAGGAGAA 
GGCATGGTGA AGCTGCTGGA TGAGCTGTCC CCTGACACAG CACCTCACAA ATACTATATT 
GGATTCCGGT ACGTCCATCC CTTGACAGAA GAGGCAATTG AAGAGATGGA GAGAGATGGA 
CTAGAAAGGG CCATTGCTTT CACACAGTAT CCACAGTACA GCTGCTCCAC CACAGGCAGC 
AGCTTAAATG CCATTTACAG ATACTATAAC GAGGTGGGGC GGAAGCCCAC CATGAAGTGG 
AGCACTATCG ACAGGTGGCC CACGCACCCC CTCCTCATCC AGTGCTTTGC AGACCACATT 
CTGAAAGAGC TGGACCATTT TCCAGAGGAG AAGAGAAGTG AGGTGGTCAT TCTGTTTTCT 
GCCCACTCCC TGCCGATGTC TGTTGTCAAC AGAGGGGACC CCTATCCCCA AGAGGTAGGA 
GCCACTGTCC ACAGAGTCAT GGAGCAGCTG GGTTATCCGA ACCCCTACCG ACTGGTCTGG 
CAGTCCAAGG TTGGTCCAGT ACCCTGGTTG GGCCCTCAAA CAGATGAGGC TATCAAAGGG 
CTTTGTGAGC GGGGGAGGAA GAATATCCTC TTGGTTCCAA TAGCATTTAC CAGTGATCAC 
ATTGAGACCC TTTATGAACT GGACATTGAA TACTCTCAAG TGTTAGCTCA GAAGTGTGGA 
GCTGAAAACA TCAGAAGAGC AGAGTCTCTT AATGGAAATC CATTGTTCTC CAAGGCCCTT 
GCTGACCTGG TGCACTCCCA CATCCAGTCA AACAAGCTGT GCTCCACGCA GTTGAGTCTG 
AGCTGTCCGC TCTGTGTAAA TCCTGTCTGC AGGAAGACTA AATCCTTCTT CACCAGCCAA 
CAGCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101904.1
CDS	98..1366
Translation	MLSAGANMAAALRAAGALFREPLVYGSSRACQPWRCQSGPAVVATTEKAHHAKTTKPQAQPERRKPKTGILMLNMGGPETLGEVQDFLQRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKMWTSKQGEGMVKLLDELSPDTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNEVGRKPTMKWSTIDRWPTHPLLIQCFADHILKELDHFPEEKRSEVVILFSAHSLPMSVVNRGDPYPQEVGATVHRVMEQLGYPNPYRLVWQSKVGPVPWLGPQTDEAIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAQKCGAENIRRAESLNGNPLFSKALADLVHSHIQSNKLCSTQLSLSCPLCVNPVCRKTKSFFTSQQL

Target ORF information:

RefSeq Version	NM_001108434.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ferrochelatase (Fech), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108434.1

ORF Insert Sequence:

ATGCTTTCGG CCGGCGCCAA CATGGCTGCG GCCCTGCGGG CTGCGGGCGC TCTGTTCCGC 
GAGCCGCTGG TGTATGGCAG CTCGAGGGCC TGTCAGCCAT GGAGGTGCCA ATCGGGTCCA 
GCAGTGGTGG CCACTACGGA GAAAGCGCAT CATGCCAAAA CCACAAAACC ACAAGCTCAA 
CCAGAAAGGA GGAAGCCCAA AACGGGCATA TTAATGTTAA ACATGGGAGG CCCCGAAACC 
CTTGGAGAAG TTCAAGACTT CCTTCAGAGG CTCTTCCTGG ACCGAGACCT CATGACCCTT 
CCCATTCAAA ATAAGCTGGC ACCATTCATC GCCAAACGCC GAACCCCCAA AATTCAAGAG 
CAGTATCGCA GAATCGGAGG TGGATCCCCC ATCAAGATGT GGACTTCCAA GCAAGGAGAA 
GGCATGGTGA AGCTGCTGGA TGAGCTGTCC CCTGACACAG CACCTCACAA ATACTATATT 
GGATTCCGGT ACGTCCATCC CTTGACAGAA GAGGCAATTG AAGAGATGGA GAGAGATGGA 
CTAGAAAGGG CCATTGCTTT CACACAGTAT CCACAGTACA GCTGCTCCAC CACAGGCAGC 
AGCTTAAATG CCATTTACAG ATACTATAAC GAGGTGGGGC GGAAGCCCAC CATGAAGTGG 
AGCACTATCG ACAGGTGGCC CACGCACCCC CTCCTCATCC AGTGCTTTGC AGACCACATT 
CTGAAAGAGC TGGACCATTT TCCAGAGGAG AAGAGAAGTG AGGTGGTCAT TCTGTTTTCT 
GCCCACTCCC TGCCGATGTC TGTTGTCAAC AGAGGGGACC CCTATCCCCA AGAGGTAGGA 
GCCACTGTCC ACAGAGTCAT GGAGCAGCTG GGTTATCCGA ACCCCTACCG ACTGGTCTGG 
CAGTCCAAGG TTGGTCCAGT ACCCTGGTTG GGCCCTCAAA CAGATGAGGC TATCAAAGGG 
CTTTGTGAGC GGGGGAGGAA GAATATCCTC TTGGTTCCAA TAGCATTTAC CAGTGATCAC 
ATTGAGACCC TTTATGAACT GGACATTGAA TACTCTCAAG TGTTAGCTCA GAAGTGTGGA 
GCTGAAAACA TCAGAAGAGC AGAGTCTCTT AATGGAAATC CATTGTTCTC CAAGGCCCTT 
GCTGACCTGG TGCACTCCCA CATCCAGTCA AACAAGCTGT GCTCCACGCA GTTGAGTCTG 
AGCTGTCCGC TCTGTGTAAA TCCTGTCTGC AGGAAGACTA AATCCTTCTT CACCAGCCAA 
CAGCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fech ( XM_006254850.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006254912.1 Rattus norvegicus ferrochelatase (Fech), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa38451
Clone ID Related Accession (Same CDS sequence)	XM_006254850.3
Accession Version	XM_006254850.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1362bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	ferrochelatase, mitochondrial isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005117.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006254850.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGACCTG AGCCAAGGCT TGGCGAGAAG ATAAGGGTAG CTTCTAAAAA GATCAAGCCA 
CCCCTGAGAA TGGGACTTAA ACCCCAACCC ACGGGAGAAG GAGGCCTTCA GCGAGTTTCC 
CTACCTGAGG AGATGCTGGG AAAACCACCT CTGCCAGGAG TGGTGTATGG CAGCTCGAGG 
GCCTGTCAGC CATGGAGGTG CCAATCGGGT CCAGCAGTGG TGGCCACTAC GGAGAAAGCG 
CATCATGCCA AAACCACAAA ACCACAAGCT CAACCAGAAA GGAGGAAGCC CAAAACGGGC 
ATATTAATGT TAAACATGGG AGGCCCCGAA ACCCTTGGAG AAGTTCAAGA CTTCCTTCAG 
AGGCTCTTCC TGGACCGAGA CCTCATGACC CTTCCCATTC AAAATAAGCT GGCACCATTC 
ATCGCCAAAC GCCGAACCCC CAAAATTCAA GAGCAGTATC GCAGAATCGG AGGTGGATCC 
CCCATCAAGA TGTGGACTTC CAAGCAAGGA GAAGGCATGG TGAAGCTGCT GGATGAGCTG 
TCCCCTGACA CAGCACCTCA CAAATACTAT ATTGGATTCC GGTACGTCCA TCCCTTGACA 
GAAGAGGCAA TTGAAGAGAT GGAGAGAGAT GGACTAGAAA GGGCCATTGC TTTCACACAG 
TATCCACAGT ACAGCTGCTC CACCACAGGC AGCAGCTTAA ATGCCATTTA CAGATACTAT 
AACGAGGTGG GGCGGAAGCC CACCATGAAG TGGAGCACTA TCGACAGGTG GCCCACGCAC 
CCCCTCCTCA TCCAGTGCTT TGCAGACCAC ATTCTGAAAG AGCTGGACCA TTTTCCAGAG 
GAGAAGAGAA GTGAGGTGGT CATTCTGTTT TCTGCCCACT CCCTGCCGAT GTCTGTTGTC 
AACAGAGGGG ACCCCTATCC CCAAGAGGTA GGAGCCACTG TCCACAGAGT CATGGAGCAG 
CTGGGTTATC CGAACCCCTA CCGACTGGTC TGGCAGTCCA AGGTTGGTCC AGTACCCTGG 
TTGGGCCCTC AAACAGATGA GGCTATCAAA GGGCTTTGTG AGCGGGGGAG GAAGAATATC 
CTCTTGGTTC CAATAGCATT TACCAGTGAT CACATTGAGA CCCTTTATGA ACTGGACATT 
GAATACTCTC AAGTGTTAGC TCAGAAGTGT GGAGCTGAAA ACATCAGAAG AGCAGAGTCT 
CTTAATGGAA ATCCATTGTT CTCCAAGGCC CTTGCTGACC TGGTGCACTC CCACATCCAG 
TCAAACAAGC TGTGCTCCAC GCAGTTGAGT CTGAGCTGTC CGCTCTGTGT AAATCCTGTC 
TGCAGGAAGA CTAAATCCTT CTTCACCAGC CAACAGCTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006254912.1
CDS	2261..3622
Translation	MGPEPRLGEKIRVASKKIKPPLRMGLKPQPTGEGGLQRVSLPEEMLGKPPLPGVVYGSSRACQPWRCQSGPAVVATTEKAHHAKTTKPQAQPERRKPKTGILMLNMGGPETLGEVQDFLQRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKMWTSKQGEGMVKLLDELSPDTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNEVGRKPTMKWSTIDRWPTHPLLIQCFADHILKELDHFPEEKRSEVVILFSAHSLPMSVVNRGDPYPQEVGATVHRVMEQLGYPNPYRLVWQSKVGPVPWLGPQTDEAIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAQKCGAENIRRAESLNGNPLFSKALADLVHSHIQSNKLCSTQLSLSCPLCVNPVCRKTKSFFTSQQL

Target ORF information:

RefSeq Version	XM_006254850.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ferrochelatase (Fech), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006254850.3

ORF Insert Sequence:

ATGGGACCTG AGCCAAGGCT TGGCGAGAAG ATAAGGGTAG CTTCTAAAAA GATCAAGCCA 
CCCCTGAGAA TGGGACTTAA ACCCCAACCC ACGGGAGAAG GAGGCCTTCA GCGAGTTTCC 
CTACCTGAGG AGATGCTGGG AAAACCACCT CTGCCAGGAG TGGTGTATGG CAGCTCGAGG 
GCCTGTCAGC CATGGAGGTG CCAATCGGGT CCAGCAGTGG TGGCCACTAC GGAGAAAGCG 
CATCATGCCA AAACCACAAA ACCACAAGCT CAACCAGAAA GGAGGAAGCC CAAAACGGGC 
ATATTAATGT TAAACATGGG AGGCCCCGAA ACCCTTGGAG AAGTTCAAGA CTTCCTTCAG 
AGGCTCTTCC TGGACCGAGA CCTCATGACC CTTCCCATTC AAAATAAGCT GGCACCATTC 
ATCGCCAAAC GCCGAACCCC CAAAATTCAA GAGCAGTATC GCAGAATCGG AGGTGGATCC 
CCCATCAAGA TGTGGACTTC CAAGCAAGGA GAAGGCATGG TGAAGCTGCT GGATGAGCTG 
TCCCCTGACA CAGCACCTCA CAAATACTAT ATTGGATTCC GGTACGTCCA TCCCTTGACA 
GAAGAGGCAA TTGAAGAGAT GGAGAGAGAT GGACTAGAAA GGGCCATTGC TTTCACACAG 
TATCCACAGT ACAGCTGCTC CACCACAGGC AGCAGCTTAA ATGCCATTTA CAGATACTAT 
AACGAGGTGG GGCGGAAGCC CACCATGAAG TGGAGCACTA TCGACAGGTG GCCCACGCAC 
CCCCTCCTCA TCCAGTGCTT TGCAGACCAC ATTCTGAAAG AGCTGGACCA TTTTCCAGAG 
GAGAAGAGAA GTGAGGTGGT CATTCTGTTT TCTGCCCACT CCCTGCCGAT GTCTGTTGTC 
AACAGAGGGG ACCCCTATCC CCAAGAGGTA GGAGCCACTG TCCACAGAGT CATGGAGCAG 
CTGGGTTATC CGAACCCCTA CCGACTGGTC TGGCAGTCCA AGGTTGGTCC AGTACCCTGG 
TTGGGCCCTC AAACAGATGA GGCTATCAAA GGGCTTTGTG AGCGGGGGAG GAAGAATATC 
CTCTTGGTTC CAATAGCATT TACCAGTGAT CACATTGAGA CCCTTTATGA ACTGGACATT 
GAATACTCTC AAGTGTTAGC TCAGAAGTGT GGAGCTGAAA ACATCAGAAG AGCAGAGTCT 
CTTAATGGAA ATCCATTGTT CTCCAAGGCC CTTGCTGACC TGGTGCACTC CCACATCCAG 
TCAAACAAGC TGTGCTCCAC GCAGTTGAGT CTGAGCTGTC CGCTCTGTGT AAATCCTGTC 
TGCAGGAAGA CTAAATCCTT CTTCACCAGC CAACAGCTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Erythropoietic protoporphyria a clinical and molecular study from Lebanon: Ferrochelatase a potential tumor suppressor gene in colon cancer.
Clinical genetics92(5)495-502(2017 Nov)
Kadara H,Nemer G,Safi R,Rebeiz N,Daou L,Delbani D,Btadini W,Abbas O,Tofaili M,Bitar F,Kibbi AG,Shimomura Y,Kurban M

Synthesis, delivery and regulation of eukaryotic heme and Fe-S cluster cofactors.
Archives of biochemistry and biophysics59260-75(2016 Feb)
Barupala DP,Dzul SP,Riggs-Gelasco PJ,Stemmler TL

Incomplete erythropoietic protoporphyria caused by a splice site modulator homozygous IVS3-48C polymorphism in the ferrochelatase gene.
The British journal of dermatology174(1)172-5(2016 Jan)
Mizawa M,Makino T,Nakano H,Sawamura D,Shimizu T

A Novel Mutation in the FECH Gene in a Czech Family with Erythropoietic Protoporphyria and a Population Study of IVS3-48C Variant Contributing to the Disease.
Folia biologica61(6)227-32(2015)
Farrag MS,Ku?erov? J,?lachtov? L,?eda O,?perl J,Mart?sek P

HRG1 is essential for heme transport from the phagolysosome of macrophages during erythrophagocytosis.
Cell metabolism17(2)261-70(2013 Feb)
White C,Yuan X,Schmidt PJ,Bresciani E,Samuel TK,Campagna D,Hall C,Bishop K,Calicchio ML,Lapierre A,Ward DM,Liu P,Fleming MD,Hamza I

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Fech cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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