Slc47a1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc47a1
Entrez Gene ID	360539
Full Name	solute carrier family 47 member 1
Synonyms	MATE1,RGD1311123
General protein information	Preferred Names solute carrier family 47 member 1 Names multidrug and toxin extrusion protein 1 H+/organic cation antiporter variant 1 H+/organic cation antiporter variant 2 MATE-1 rMATE-1 solute carrier family 47 (multidrug and toxin extrusion), member 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 10 Map Location: 10q22

mRNA and Protein(s)

mRNA	Protein	Name
NM_001014118.2	NP_001014140.1	multidrug and toxin extrusion protein 1
XM_017597374.1	XP_017452863.1	multidrug and toxin extrusion protein 1 isoform X1

Pathways from BioSystems

Homologies

	LOC703544	XP_002800377.1
Neurospora crassa	NCU07720	XP_961970.2
Oryza sativa (rice)	Os10g0344900	NP_001064393.1
Schizosaccharomyces pombe (fission yeast)	SPCC4B3.13	NP_588077.1
Arabidopsis thaliana (thale cress)	AT2G34360	NP_180983.4
Oryza sativa (rice)	Os10g0345100	NP_001064394.1
Oryza sativa (rice)	Os06g0495500	NP_001057690.1
Xenopus tropicalis (tropical clawed frog)	LOC100498310	XP_002934402.2
Homo sapiens (human)	SLC47A1	NP_060712.2
Bos taurus (cattle)	SLC47A1	XP_002695911.2
Saccharomyces cerevisiae (baker's yeast)	YDR338C	NP_010625.1
Eremothecium gossypii	AGOS_AEL099W	NP_984762.2
Magnaporthe oryzae (rice blast fungus)	MGG_04182	XP_003719641.1
Canis lupus familiaris (dog)	SLC47A1	XP_003639084.2
Mus musculus (house mouse)	Slc47a1	NP_080459.2
Rattus norvegicus (Norway rat)	Slc47a1	NP_001014140.1
Schizosaccharomyces pombe (fission yeast)	SPAC323.07c	NP_594377.1
Oryza sativa (rice)	Os06g0494400	NP_001057687.1
Oryza sativa (rice)	Os06g0495100	NP_001057689.1
Pan troglodytes (chimpanzee)	SLC47A1	XP_001144887.1
Kluyveromyces lactis	KLLA0A06952g	XP_451308.1
Arabidopsis thaliana (thale cress)	AT5G52450	NP_200058.1
Arabidopsis thaliana (thale cress)	AT1G73700	NP_177511.1

Gene Ontology
Bibliography

Related articles in PubMed

The farnesoid X receptor agonist obeticholic acid upregulates biliary excretion of asymmetric dimethylarginine via MATE-1 during hepatic ischemia/reperfusion injury.
Ferrigno A, Di Pasqua LG, Berardo C, Siciliano V, Rizzo V, Adorini L, Richelmi P, Vairetti M
PloS one13(1)e0191430(2018)

Inhibitory effect of atenolol on urinary excretion of metformin via down-regulating multidrug and toxin extrusion protein 1 (rMate1) expression in the kidney of rats.
Ma YR, Huang J, Shao YY, Ma K, Zhang GQ, Zhou Y, Zhi R, Qin HY, Wu XA
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences6818-26(2015 Feb)

Underestimation of urinary biomarker-to-creatinine ratio resulting from age-related gain in muscle mass in rats.
Tonomura Y, Morikawa Y, Takagi S, Torii M, Matsubara M
Toxicology303169-76(2013 Jan)

Metformin pathways: pharmacokinetics and pharmacodynamics.
Gong L, Goswami S, Giacomini KM, Altman RB, Klein TE
Pharmacogenetics and genomics22(11)820-7(2012 Nov)

Membrane transporters as mediators of Cisplatin effects and side effects.
Ciarimboli G
Scientifica2012473829(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Inhibitory effect of atenolol on urinary excretion of metformin via down-regulating MATE1 expression in the kidney of rats
Title: Inhibitory effect of atenolol on urinary excretion of metformin via down-regulating multidrug and toxin extrusion protein 1 (rMate1) expression in the kidney of rats.

renal mRNA level of multidrug and toxin extrusions-1 did not show an age-related increase; the increase in creatinine clearance highly contributed to the age-related increase in urinary creatinine excretion compared to mRNA levels of Oct2 and Mate1
Title: Underestimation of urinary biomarker-to-creatinine ratio resulting from age-related gain in muscle mass in rats.

Sp1 functions as basal transcriptional regulator of human and rat MATE1 gene through two GC boxes. May be conserved among species. We have identified rSNP of hMATE1 gene (G-32A) (belonging to Sp1-binding site) that affects promoter activity.
Title: Critical roles of Sp1 in gene expression of human and rat H+/organic cation antiporter MATE1.

MATE1 is expressed in the renal proximal tubules and can mediate the transport of various organic cations and cephalexin using an oppositely directed H+ gradient
Title: Molecular cloning, functional characterization and tissue distribution of rat H+/organic cation antiporter MATE1.

The following Slc47a1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc47a1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa05041	NM_001014118.2 Latest version!	Rattus norvegicus solute carrier family 47 member 1 (Slc47a1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
ORa57381	XM_017597374.1 Latest version!	Rattus norvegicus solute carrier family 47 member 1 (Slc47a1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$307.30 $439.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc47a1 ( NM_001014118.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001014140.1 Rattus norvegicus solute carrier family 47 member 1 (Slc47a1), mRNA.

Price & Availability↑

CloneID	ORa05041
Clone ID Related Accession (Same CDS sequence)	NM_001014118.2
Accession Version	NM_001014118.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1701bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-17
Organism	Rattus norvegicus(Norway rat)
Product	multidrug and toxin extrusion protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB248823.1. On Jun 10, 2007 this sequence version replaced NM_001014118.1. ##Evidence-Data-START## Transcript exon combination :: AB248823.1, AB248824.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGAGGTCT TGGAGGAGCC TGCGCCGGGA CCAGGAGGCG CGGACGCAGC CGAGCGCCGT 
GGGCTGCGCC GCCTGTTGCT GTCTGGCTTT CAAGAGGAGC TGCGGGCTCT CTTGGTCCTG 
GCGGGTCCTG CGTTCTTGGC CCAGCTCATG ATGTTCTTAA TCAGTTTCAT AAGTTCAGTG 
TTCTGTGGCC ACTTGGGCAA GCTGGAGCTG GACGCCGTCA CACTGGCAAT TGCGGTTATC 
AATGTCACAG GCATTTCAGT GGGACATGGC CTATCTTCTG CTTGTGACAC CCTCATCTCC 
CAGACATACG GGAGCCAGAA CTTGAAGCAT GTAGGGGTTA TCCTGCAGAG GGGGACACTC 
ATCCTGCTCC TCTGCTGCTT CCCATGCTGG GCACTCTTCA TCAACACCGA GCAAATTCTG 
CTGCTCTTCA GACAGGACCC AGATGTATCC AGGCTCACCC AGACTTACGT CATGGTCTTC 
ATTCCAGCAC TCCCTGCAGC CTTTCTTTAT ACGTTACAAG TTAAATACTT GCTCAACCAG 
GGCATCGTTC TGCCTCAGGT TATAACGGGC ATCGCTGCTA ACCTTGTCAA CGCCCTGGCC 
AACTATCTGT TTCTCCATCA GCTACATCTT GGGGTGATGG GTTCAGCGTT GGCCAATACC 
ATCTCCCAGT TTGCTCTGGC CATCTTCCTG TTCCTCTACA TTCTCTGGAG AAAACTACAT 
CATGCCACCT GGGGAGGATG GTCCTGGGAG TGTCTGCAGG ACTGGGCCTC CTTCCTGCAA 
CTGGCTATCC CCAGCATGCT CATGCTGTGC ATAGAGTGGT GGGCCTATGA GGTTGGCAGC 
TTCCTGAGTG GTATCCTTGG CATGGTGGAG TTGGGAGCCC AGTCCATCAC CTATGAATTG 
GCTATCATTG TATACATGAT CCCTGCAGGC TTCAGTGTGG CTGCCAATGT CCGGGTGGGA 
AATGCGTTGG GTGCAGGAAA CATTGACCAG GCCAAGAAGT CTTCAGCAAT TTCCTTGATA 
GTCACAGAGC TCTTTGCTGT GACCTTCTGT GTCCTGCTGC TGGGCTGTAA GGATCTCGTG 
GGCTACATTT TCACCACTGA CTGGGATATT GTGGCCTTGG TGGCTCAAGT GGTCCCCATT 
TACGCTGTGT CCCACCTCTT TGAAGCTCTT GCCTGTACCT GTGGTGGCGT TCTGAGGGGC 
ACTGGAAACC AGAAGGTTGG AGCCATCGTT AATGCCATCG GCTATTATGT CATCGGCCTC 
CCCATCGGGA TCTCACTGAT GTTCGTTGCC AAGCTGGGAG TGATTGGTCT GTGGTCAGGA 
ATCATCATCT GCTCTGTCTG TCAGACTTCG TGCTTCCTGG TTTTTATTGC TCGGCTTAAT 
TGGAAACTCG CCTGTCAACA GGCTCAAGTA CATGCCAATT TGAAGGTAAA TGTGGCCCTG 
AATTCTGCTG TCTCTCAGGA GCCTGCTCAC CCAGTGGGTC CTGAGAGCCA TGGAGAAATC 
ATGATGACAG ATCTTGAAAA AAAAGATGAG ATTCAATTGG ACCAGCAGAT GAACCAGCAA 
CAAGCTTTGC CTGTCCATCC AAAGGACAGC AATAAACTGT CTGGGAAACA GTTGGCCCTA 
CGTCGAGGGC TCCTATTCCT CGGGGTAGTC TTAGTCTTGG TGGGTGGGAT TTTAGTGAGA 
GTCTATATCA GAACTGAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001014140.1
CDS	4..1704
Translation	MEVLEEPAPGPGGADAAERRGLRRLLLSGFQEELRALLVLAGPAFLAQLMMFLISFISSVFCGHLGKLELDAVTLAIAVINVTGISVGHGLSSACDTLISQTYGSQNLKHVGVILQRGTLILLLCCFPCWALFINTEQILLLFRQDPDVSRLTQTYVMVFIPALPAAFLYTLQVKYLLNQGIVLPQVITGIAANLVNALANYLFLHQLHLGVMGSALANTISQFALAIFLFLYILWRKLHHATWGGWSWECLQDWASFLQLAIPSMLMLCIEWWAYEVGSFLSGILGMVELGAQSITYELAIIVYMIPAGFSVAANVRVGNALGAGNIDQAKKSSAISLIVTELFAVTFCVLLLGCKDLVGYIFTTDWDIVALVAQVVPIYAVSHLFEALACTCGGVLRGTGNQKVGAIVNAIGYYVIGLPIGISLMFVAKLGVIGLWSGIIICSVCQTSCFLVFIARLNWKLACQQAQVHANLKVNVALNSAVSQEPAHPVGPESHGEIMMTDLEKKDEIQLDQQMNQQQALPVHPKDSNKLSGKQLALRRGLLFLGVVLVLVGGILVRVYIRTE

Target ORF information:

RefSeq Version	NM_001014118.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 47 member 1 (Slc47a1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001014118.2

ORF Insert Sequence:

ATGGAGGTCT TGGAGGAGCC TGCGCCGGGA CCAGGAGGCG CGGACGCAGC CGAGCGCCGT 
GGGCTGCGCC GCCTGTTGCT GTCTGGCTTT CAAGAGGAGC TGCGGGCTCT CTTGGTCCTG 
GCGGGTCCTG CGTTCTTGGC CCAGCTCATG ATGTTCTTAA TCAGTTTCAT AAGTTCAGTG 
TTCTGTGGCC ACTTGGGCAA GCTGGAGCTG GACGCCGTCA CACTGGCAAT TGCGGTTATC 
AATGTCACAG GCATTTCAGT GGGACATGGC CTATCTTCTG CTTGTGACAC CCTCATCTCC 
CAGACATACG GGAGCCAGAA CTTGAAGCAT GTAGGGGTTA TCCTGCAGAG GGGGACACTC 
ATCCTGCTCC TCTGCTGCTT CCCATGCTGG GCACTCTTCA TCAACACCGA GCAAATTCTG 
CTGCTCTTCA GACAGGACCC AGATGTATCC AGGCTCACCC AGACTTACGT CATGGTCTTC 
ATTCCAGCAC TCCCTGCAGC CTTTCTTTAT ACGTTACAAG TTAAATACTT GCTCAACCAG 
GGCATCGTTC TGCCTCAGGT TATAACGGGC ATCGCTGCTA ACCTTGTCAA CGCCCTGGCC 
AACTATCTGT TTCTCCATCA GCTACATCTT GGGGTGATGG GTTCAGCGTT GGCCAATACC 
ATCTCCCAGT TTGCTCTGGC CATCTTCCTG TTCCTCTACA TTCTCTGGAG AAAACTACAT 
CATGCCACCT GGGGAGGATG GTCCTGGGAG TGTCTGCAGG ACTGGGCCTC CTTCCTGCAA 
CTGGCTATCC CCAGCATGCT CATGCTGTGC ATAGAGTGGT GGGCCTATGA GGTTGGCAGC 
TTCCTGAGTG GTATCCTTGG CATGGTGGAG TTGGGAGCCC AGTCCATCAC CTATGAATTG 
GCTATCATTG TATACATGAT CCCTGCAGGC TTCAGTGTGG CTGCCAATGT CCGGGTGGGA 
AATGCGTTGG GTGCAGGAAA CATTGACCAG GCCAAGAAGT CTTCAGCAAT TTCCTTGATA 
GTCACAGAGC TCTTTGCTGT GACCTTCTGT GTCCTGCTGC TGGGCTGTAA GGATCTCGTG 
GGCTACATTT TCACCACTGA CTGGGATATT GTGGCCTTGG TGGCTCAAGT GGTCCCCATT 
TACGCTGTGT CCCACCTCTT TGAAGCTCTT GCCTGTACCT GTGGTGGCGT TCTGAGGGGC 
ACTGGAAACC AGAAGGTTGG AGCCATCGTT AATGCCATCG GCTATTATGT CATCGGCCTC 
CCCATCGGGA TCTCACTGAT GTTCGTTGCC AAGCTGGGAG TGATTGGTCT GTGGTCAGGA 
ATCATCATCT GCTCTGTCTG TCAGACTTCG TGCTTCCTGG TTTTTATTGC TCGGCTTAAT 
TGGAAACTCG CCTGTCAACA GGCTCAAGTA CATGCCAATT TGAAGGTAAA TGTGGCCCTG 
AATTCTGCTG TCTCTCAGGA GCCTGCTCAC CCAGTGGGTC CTGAGAGCCA TGGAGAAATC 
ATGATGACAG ATCTTGAAAA AAAAGATGAG ATTCAATTGG ACCAGCAGAT GAACCAGCAA 
CAAGCTTTGC CTGTCCATCC AAAGGACAGC AATAAACTGT CTGGGAAACA GTTGGCCCTA 
CGTCGAGGGC TCCTATTCCT CGGGGTAGTC TTAGTCTTGG TGGGTGGGAT TTTAGTGAGA 
GTCTATATCA GAACTGAATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc47a1 ( XM_017597374.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017452863.1 Rattus norvegicus solute carrier family 47 member 1 (Slc47a1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa57381
Clone ID Related Accession (Same CDS sequence)	XM_017597374.1
Accession Version	XM_017597374.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1554bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	multidrug and toxin extrusion protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGTTCT TAATCAGTTT CATAAGTTCA GTGTTCTGTG GCCACTTGGG CAAGCTGGAG 
CTGGACGCCG TCACACTGGC AATTGCGGTT ATCAATGTCA CAGGCATTTC AGTGGGACAT 
GGCCTATCTT CTGCTTGTGA CACCCTCATC TCCCAGACAT ACGGGAGCCA GAACTTGAAG 
CATGTAGGGG TTATCCTGCA GAGGGGGACA CTCATCCTGC TCCTCTGCTG CTTCCCATGC 
TGGGCACTCT TCATCAACAC CGAGCAAATT CTGCTGCTCT TCAGACAGGA CCCAGATGTA 
TCCAGGCTCA CCCAGACTTA CGTCATGGTC TTCATTCCAG CACTCCCTGC AGCCTTTCTT 
TATACGTTAC AAGTTAAATA CTTGCTCAAC CAGGGCATCG TTCTGCCTCA GGTTATAACG 
GGCATCGCTG CTAACCTTGT CAACGCCCTG GCCAACTATC TGTTTCTCCA TCAGCTACAT 
CTTGGGGTGA TGGGTTCAGC GTTGGCCAAT ACCATCTCCC AGTTTGCTCT GGCCATCTTC 
CTGTTCCTCT ACATTCTCTG GAGAAAACTA CATCATGCCA CCTGGGGAGG ATGGTCCTGG 
GAGTGTCTGC AGGACTGGGC CTCCTTCCTG CAACTGGCTA TCCCCAGCAT GCTCATGCTG 
TGCATAGAGT GGTGGGCCTA TGAGGTTGGC AGCTTCCTGA GTGGTATCCT TGGCATGGTG 
GAGTTGGGAG CCCAGTCCAT CACCTATGAA TTGGCTATCA TTGTATACAT GATCCCTGCA 
GGCTTCAGTG TGGCTGCCAA TGTCCGGGTG GGAAATGCGT TGGGTGCAGG AAACATTGAC 
CAGGCCAAGA AGTCTTCAGC AATTTCCTTG ATAGTCACAG AGCTCTTTGC TGTGACCTTC 
TGTGTCCTGC TGCTGGGCTG TAAGGATCTC GTGGGCTACA TTTTCACCAC TGACTGGGAT 
ATTGTGGCCT TGGTGGCTCA AGTGGTCCCC ATTTACGCTG TGTCCCACCT CTTTGAAGCT 
CTTGCCTGTA CCTGTGGTGG CGTTCTGAGG GGCACTGGAA ACCAGAAGGT TGGAGCCATC 
GTTAATGCCA TCGGCTATTA TGTCATCGGC CTCCCCATCG GGATCTCACT GATGTTCGTT 
GCCAAGCTGG GAGTGATTGG TCTGTGGTCA GGAATCATCA TCTGCTCTGT CTGTCAGACT 
TCGTGCTTCC TGGTTTTTAT TGCTCGGCTT AATTGGAAAC TCGCCTGTCA ACAGGCTCAA 
GTACATGCCA ATTTGAAGGT AAATGTGGCC CTGAATTCTG CTGTCTCTCA GGAGCCTGCT 
CACCCAGTGG GTCCTGAGAG CCATGGAGAA ATCATGATGA CAGATCTTGA AAAAAAAGAT 
GAGATTCAAT TGGACCAGCA GATGAACCAG CAACAAGCTT TGCCTGTCCA TCCAAAGGAC 
AGCAATAAAC TGTCTGGGAA ACAGTTGGCC CTACGTCGAG GGCTCCTATT CCTCGGGGTA 
GTCTTAGTCT TGGTGGGTGG GATTTTAGTG AGAGTCTATA TCAGAACTGA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017452863.1
CDS	156..1709
Translation	MMFLISFISSVFCGHLGKLELDAVTLAIAVINVTGISVGHGLSSACDTLISQTYGSQNLKHVGVILQRGTLILLLCCFPCWALFINTEQILLLFRQDPDVSRLTQTYVMVFIPALPAAFLYTLQVKYLLNQGIVLPQVITGIAANLVNALANYLFLHQLHLGVMGSALANTISQFALAIFLFLYILWRKLHHATWGGWSWECLQDWASFLQLAIPSMLMLCIEWWAYEVGSFLSGILGMVELGAQSITYELAIIVYMIPAGFSVAANVRVGNALGAGNIDQAKKSSAISLIVTELFAVTFCVLLLGCKDLVGYIFTTDWDIVALVAQVVPIYAVSHLFEALACTCGGVLRGTGNQKVGAIVNAIGYYVIGLPIGISLMFVAKLGVIGLWSGIIICSVCQTSCFLVFIARLNWKLACQQAQVHANLKVNVALNSAVSQEPAHPVGPESHGEIMMTDLEKKDEIQLDQQMNQQQALPVHPKDSNKLSGKQLALRRGLLFLGVVLVLVGGILVRVYIRTE

Target ORF information:

RefSeq Version	XM_017597374.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 47 member 1 (Slc47a1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017597374.1

ORF Insert Sequence:

ATGATGTTCT TAATCAGTTT CATAAGTTCA GTGTTCTGTG GCCACTTGGG CAAGCTGGAG 
CTGGACGCCG TCACACTGGC AATTGCGGTT ATCAATGTCA CAGGCATTTC AGTGGGACAT 
GGCCTATCTT CTGCTTGTGA CACCCTCATC TCCCAGACAT ACGGGAGCCA GAACTTGAAG 
CATGTAGGGG TTATCCTGCA GAGGGGGACA CTCATCCTGC TCCTCTGCTG CTTCCCATGC 
TGGGCACTCT TCATCAACAC CGAGCAAATT CTGCTGCTCT TCAGACAGGA CCCAGATGTA 
TCCAGGCTCA CCCAGACTTA CGTCATGGTC TTCATTCCAG CACTCCCTGC AGCCTTTCTT 
TATACGTTAC AAGTTAAATA CTTGCTCAAC CAGGGCATCG TTCTGCCTCA GGTTATAACG 
GGCATCGCTG CTAACCTTGT CAACGCCCTG GCCAACTATC TGTTTCTCCA TCAGCTACAT 
CTTGGGGTGA TGGGTTCAGC GTTGGCCAAT ACCATCTCCC AGTTTGCTCT GGCCATCTTC 
CTGTTCCTCT ACATTCTCTG GAGAAAACTA CATCATGCCA CCTGGGGAGG ATGGTCCTGG 
GAGTGTCTGC AGGACTGGGC CTCCTTCCTG CAACTGGCTA TCCCCAGCAT GCTCATGCTG 
TGCATAGAGT GGTGGGCCTA TGAGGTTGGC AGCTTCCTGA GTGGTATCCT TGGCATGGTG 
GAGTTGGGAG CCCAGTCCAT CACCTATGAA TTGGCTATCA TTGTATACAT GATCCCTGCA 
GGCTTCAGTG TGGCTGCCAA TGTCCGGGTG GGAAATGCGT TGGGTGCAGG AAACATTGAC 
CAGGCCAAGA AGTCTTCAGC AATTTCCTTG ATAGTCACAG AGCTCTTTGC TGTGACCTTC 
TGTGTCCTGC TGCTGGGCTG TAAGGATCTC GTGGGCTACA TTTTCACCAC TGACTGGGAT 
ATTGTGGCCT TGGTGGCTCA AGTGGTCCCC ATTTACGCTG TGTCCCACCT CTTTGAAGCT 
CTTGCCTGTA CCTGTGGTGG CGTTCTGAGG GGCACTGGAA ACCAGAAGGT TGGAGCCATC 
GTTAATGCCA TCGGCTATTA TGTCATCGGC CTCCCCATCG GGATCTCACT GATGTTCGTT 
GCCAAGCTGG GAGTGATTGG TCTGTGGTCA GGAATCATCA TCTGCTCTGT CTGTCAGACT 
TCGTGCTTCC TGGTTTTTAT TGCTCGGCTT AATTGGAAAC TCGCCTGTCA ACAGGCTCAA 
GTACATGCCA ATTTGAAGGT AAATGTGGCC CTGAATTCTG CTGTCTCTCA GGAGCCTGCT 
CACCCAGTGG GTCCTGAGAG CCATGGAGAA ATCATGATGA CAGATCTTGA AAAAAAAGAT 
GAGATTCAAT TGGACCAGCA GATGAACCAG CAACAAGCTT TGCCTGTCCA TCCAAAGGAC 
AGCAATAAAC TGTCTGGGAA ACAGTTGGCC CTACGTCGAG GGCTCCTATT CCTCGGGGTA 
GTCTTAGTCT TGGTGGGTGG GATTTTAGTG AGAGTCTATA TCAGAACTGA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The farnesoid X receptor agonist obeticholic acid upregulates biliary excretion of asymmetric dimethylarginine via MATE-1 during hepatic ischemia/reperfusion injury.
PloS one13(1)e0191430(2018)
Ferrigno A,Di Pasqua LG,Berardo C,Siciliano V,Rizzo V,Adorini L,Richelmi P,Vairetti M

Inhibitory effect of atenolol on urinary excretion of metformin via down-regulating multidrug and toxin extrusion protein 1 (rMate1) expression in the kidney of rats.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences6818-26(2015 Feb)
Ma YR,Huang J,Shao YY,Ma K,Zhang GQ,Zhou Y,Zhi R,Qin HY,Wu XA

Underestimation of urinary biomarker-to-creatinine ratio resulting from age-related gain in muscle mass in rats.
Toxicology303169-76(2013 Jan)
Tonomura Y,Morikawa Y,Takagi S,Torii M,Matsubara M

Metformin pathways: pharmacokinetics and pharmacodynamics.
Pharmacogenetics and genomics22(11)820-7(2012 Nov)
Gong L,Goswami S,Giacomini KM,Altman RB,Klein TE

Membrane transporters as mediators of Cisplatin effects and side effects.
Scientifica2012473829(2012)
Ciarimboli G

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Slc47a1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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