Crip2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Crip2
Entrez Gene ID	338401
Full Name	cysteine-rich protein 2
Synonyms	CRP2
General protein information	Preferred Names cysteine-rich protein 2 Names cysteine-rich protein 2 CRP-2 LIM/double zinc-finger protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 6 Map Location: 6q32
Summary	mouse homolog binds the PDZ domain of protein tyrophosphatase PTP-BL and may play a role in the actin cytoskeleton [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_008764943.1	XP_008763165.1	cysteine-rich protein 2 isoform X1
NM_022501.1	NP_071946.1	cysteine-rich protein 2

Pathways from BioSystems

Homologies

	LOC710186	XP_002808516.1
Mus musculus (house mouse)	Crip2	NP_077185.1
Rattus norvegicus (Norway rat)	Crip2	NP_071946.1
Xenopus tropicalis (tropical clawed frog)	crip2	NP_001072735.1
Gallus gallus (chicken)	CRIP2	XP_422218.4
Danio rerio (zebrafish)	zgc:101840	NP_001005968.1

Gene Ontology
Bibliography

Related articles in PubMed

Proteomics characterization of extracellular space components in the human aorta.
Didangelos A, Yin X, Mandal K, Baumert M, Jahangiri M, Mayr M
Molecular & cellular proteomics : MCP9(9)2048-62(2010 Sep)

Polyclonal antibodies to LIM proteins CRP2 and CRIP2 reveal their subcellular localizations in olfactory precursor cells.
Gao X, Sun JY, Cao ZY, Lin Y, Zha DJ, Wang F, Xue T, Qiao L, Lu LJ, Qiu JH
Biochemistry. Biokhimiia74(3)336-41(2009 Mar)

Cloning and characterization of mCRIP2, a mouse LIM-only protein that interacts with PDZ domain IV of PTP-BL.
van Ham M, Croes H, Schepens J, Fransen J, Wieringa B, Hendriks W
Genes to cells : devoted to molecular & cellular mechanisms8(7)631-44(2003 Jul)

Genetic approach and phenotype-based complementation screening for identification of stroma cell-derived proteins involved in cell proliferation.
Tulin EE, Onoda N, Hasegawa M, Nosaka T, Nomura H, Kitamura T
Experimental cell research272(1)23-31(2002 Jan)

Cloning of CRP2, a novel member of the cysteine-rich protein family with two repeats of an unusual LIM/double zinc-finger motif.
Okano I, Yamamoto T, Kaji A, Kimura T, Mizuno K, Nakamura T
FEBS letters333(1-2)51-5(1993 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results demonstrated that in undifferentiated olfactory precursor cells Csrp2 was distributed both in the nucleus and the cytoplasm, whereas CRIP2 was predominantly localized in the cytoplasm.
Title: Polyclonal antibodies to LIM proteins CRP2 and CRIP2 reveal their subcellular localizations in olfactory precursor cells.

The following Crip2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Crip2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa05777	NM_022501.1 Latest version!	Rattus norvegicus cysteine-rich protein 2 (Crip2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
ORa47642	XM_008764943.1 Latest version!	Rattus norvegicus cysteine-rich protein 2 (Crip2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Crip2 ( NM_022501.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_071946.1 Rattus norvegicus cysteine-rich protein 2 (Crip2), mRNA.

Price & Availability↑

CloneID	ORa05777
Clone ID Related Accession (Same CDS sequence)	NM_022501.1
Accession Version	NM_022501.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 627bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Rattus norvegicus(Norway rat)
Product	cysteine-rich protein 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from D17512.1. ##Evidence-Data-START## Transcript exon combination :: D17512.1, FQ233584.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCCTCCA AGTGTCCCAA GTGTGACAAG ACCGTGTACT TCGCCGAGAA GGTGAGCTCC 
CTGGGCAAGG ACTGGCACAA GTTCTGCCTC AAGTGTGAGC GCTGCAACAA GACACTGACG 
CCTGGCGGCC ATGCTGAGCA TGATGGGAAA CCCTTCTGCC ACAAGCCCTG TTATGCCACA 
CTGTTTGGAC CCAAAGGCGT GAATATCGGG GGCGCTGGTT CCTACATCTA CGAGAAGCCT 
CCGACGGAGG CCCCTCAGGT CACTGGCCCC ATCGAGGTCC CTGTGGTACG AACTGAAGAG 
CGGAAGACCA GCGGGCCGCC CAAGGGTCCC AGCAAAGCCT CTAGTGTCAC CACGTTCACT 
GGGGAGCCCA ACATGTGCCC TCGATGCAAC AAGAGAGTGT ACTTCGCTGA GAAGGTGACC 
TCCCTGGGCA AGGACTGGCA CCGACCCTGC CTGCGCTGTG AGCGCTGCTC CAAGACACTG 
ACCCCAGGCG GGCATGCTGA GCATGATGGC CAACCCTACT GCCACAAGCC CTGCTATGGA 
ATACTCTTTG GACCCAAAGG AGTGAATACT GGTGCTGTGG GCAGCTACAT CTACGACAAG 
GACCCGGAAG GCACAGTTCA GCCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071946.1
CDS	57..683
Translation	MASKCPKCDKTVYFAEKVSSLGKDWHKFCLKCERCNKTLTPGGHAEHDGKPFCHKPCYATLFGPKGVNIGGAGSYIYEKPPTEAPQVTGPIEVPVVRTEERKTSGPPKGPSKASSVTTFTGEPNMCPRCNKRVYFAEKVTSLGKDWHRPCLRCERCSKTLTPGGHAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDKDPEGTVQP

Target ORF information:

RefSeq Version	NM_022501.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cysteine-rich protein 2 (Crip2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022501.1

ORF Insert Sequence:

ATGGCCTCCA AGTGTCCCAA GTGTGACAAG ACCGTGTACT TCGCCGAGAA GGTGAGCTCC 
CTGGGCAAGG ACTGGCACAA GTTCTGCCTC AAGTGTGAGC GCTGCAACAA GACACTGACG 
CCTGGCGGCC ATGCTGAGCA TGATGGGAAA CCCTTCTGCC ACAAGCCCTG TTATGCCACA 
CTGTTTGGAC CCAAAGGCGT GAATATCGGG GGCGCTGGTT CCTACATCTA CGAGAAGCCT 
CCGACGGAGG CCCCTCAGGT CACTGGCCCC ATCGAGGTCC CTGTGGTACG AACTGAAGAG 
CGGAAGACCA GCGGGCCGCC CAAGGGTCCC AGCAAAGCCT CTAGTGTCAC CACGTTCACT 
GGGGAGCCCA ACATGTGCCC TCGATGCAAC AAGAGAGTGT ACTTCGCTGA GAAGGTGACC 
TCCCTGGGCA AGGACTGGCA CCGACCCTGC CTGCGCTGTG AGCGCTGCTC CAAGACACTG 
ACCCCAGGCG GGCATGCTGA GCATGATGGC CAACCCTACT GCCACAAGCC CTGCTATGGA 
ATACTCTTTG GACCCAAAGG AGTGAATACT GGTGCTGTGG GCAGCTACAT CTACGACAAG 
GACCCGGAAG GCACAGTTCA GCCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Crip2 ( XM_008764943.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008763165.1 Rattus norvegicus cysteine-rich protein 2 (Crip2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa47642
Clone ID Related Accession (Same CDS sequence)	XM_008764943.1
Accession Version	XM_008764943.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 255bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	cysteine-rich protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005105.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCCCTC GATGCAACAA GAGAGTGTAC TTCGCTGAGA AGGTGACCTC CCTGGGCAAG 
GACTGGCACC GACCCTGCCT GCGCTGTGAG CGCTGCTCCA AGACACTGAC CCCAGGCGGG 
CATGCTGAGC ATGATGGCCA ACCCTACTGC CACAAGCCCT GCTATGGAAT ACTCTTTGGA 
CCCAAAGGAG TGAATACTGG TGCTGTGGGC AGCTACATCT ACGACAAGGA CCCGGAAGGC 
ACAGTTCAGC CTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008763165.1
CDS	693..947
Translation	MCPRCNKRVYFAEKVTSLGKDWHRPCLRCERCSKTLTPGGHAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDKDPEGTVQP

Target ORF information:

RefSeq Version	XM_008764943.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cysteine-rich protein 2 (Crip2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008764943.1

ORF Insert Sequence:

ATGTGCCCTC GATGCAACAA GAGAGTGTAC TTCGCTGAGA AGGTGACCTC CCTGGGCAAG 
GACTGGCACC GACCCTGCCT GCGCTGTGAG CGCTGCTCCA AGACACTGAC CCCAGGCGGG 
CATGCTGAGC ATGATGGCCA ACCCTACTGC CACAAGCCCT GCTATGGAAT ACTCTTTGGA 
CCCAAAGGAG TGAATACTGG TGCTGTGGGC AGCTACATCT ACGACAAGGA CCCGGAAGGC 
ACAGTTCAGC CTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Proteomics characterization of extracellular space components in the human aorta.
Molecular & cellular proteomics : MCP9(9)2048-62(2010 Sep)
Didangelos A,Yin X,Mandal K,Baumert M,Jahangiri M,Mayr M

Polyclonal antibodies to LIM proteins CRP2 and CRIP2 reveal their subcellular localizations in olfactory precursor cells.
Biochemistry. Biokhimiia74(3)336-41(2009 Mar)
Gao X,Sun JY,Cao ZY,Lin Y,Zha DJ,Wang F,Xue T,Qiao L,Lu LJ,Qiu JH

Cloning and characterization of mCRIP2, a mouse LIM-only protein that interacts with PDZ domain IV of PTP-BL.
Genes to cells : devoted to molecular & cellular mechanisms8(7)631-44(2003 Jul)
van Ham M,Croes H,Schepens J,Fransen J,Wieringa B,Hendriks W

Genetic approach and phenotype-based complementation screening for identification of stroma cell-derived proteins involved in cell proliferation.
Experimental cell research272(1)23-31(2002 Jan)
Tulin EE,Onoda N,Hasegawa M,Nosaka T,Nomura H,Kitamura T

Cloning of CRP2, a novel member of the cysteine-rich protein family with two repeats of an unusual LIM/double zinc-finger motif.
FEBS letters333(1-2)51-5(1993 Oct)
Okano I,Yamamoto T,Kaji A,Kimura T,Mizuno K,Nakamura T