Taf1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Taf1
Entrez Gene ID	317256
Full Name	TATA-box binding protein associated factor 1
Synonyms	RGD1562050
General protein information	Preferred Names TATA-box binding protein associated factor 1 Names transcription initiation factor TFIID subunit 1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: X Map Location: Xq22

mRNA and Protein(s)

mRNA	Protein	Name
NM_001191723.1	NP_001178652.1	transcription initiation factor TFIID subunit 1

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003882	XP_308108.5
Xenopus tropicalis (tropical clawed frog)	taf1	XP_002934954.2
Canis lupus familiaris (dog)	TAF1	XP_005641531.1
Mus musculus (house mouse)	Taf1	NP_001074477.1
Danio rerio (zebrafish)	taf1	NP_001038250.1
Drosophila melanogaster (fruit fly)	Taf1	NP_996159.1
Caenorhabditis elegans (roundworm)	taf-1	NP_493426.2
Homo sapiens (human)	TAF1	NP_004597.2
Rattus norvegicus (Norway rat)	Taf1	NP_001178652.1
Bos taurus (cattle)	TAF1	XP_005228102.1
Gallus gallus (chicken)	TAF1	XP_420198.4
	TAF1	XP_002808585.1

Gene Ontology
Bibliography

Related articles in PubMed

Structure of promoter-bound TFIID and model of human pre-initiation complex assembly.
Louder RK, He Y, L?pez-Blanco JR, Fang J, Chac?n P, Nogales E
Nature531(7596)604-9(2016 03)

TAF1 Variants Are Associated with Dysmorphic Features, Intellectual Disability, and Neurological Manifestations.
O'Rawe JA, Wu Y, D?rfel MJ, Rope AF, Au PY, Parboosingh JS, Moon S, Kousi M, Kosma K, Smith CS, Tzetis M, Schuette JL, Hufnagel RB, Prada CE, Martinez F, Orellana C, Crain J, Caro-Llopis A, Oltra S, Monfort S, Jim?nez-Barr?n LT, Swensen J, Ellingwood S, Smith R, Fang H, Ospina S, Stegmann S, Den Hollander N, Mittelman D, Highnam G, Robison R, Yang E, Faivre L, Roubertie A, Rivi?re JB, Monaghan KG, Wang K, Davis EE, Katsanis N, Kalscheuer VM, Wang EH, Metcalfe K, Kleefstra T, Innes AM, Kitsiou-Tzeli S, Rosello M, Keegan CE, Lyon GJ
American journal of human genetics97(6)922-32(2015 Dec)

Crystal structure of a TAF1-TAF7 complex in human transcription factor IID reveals a promoter binding module.
Wang H, Curran EC, Hinds TR, Wang EH, Zheng N
Cell research24(12)1433-44(2014 Dec)

The bromodomain: from epigenome reader to druggable target.
Sanchez R, Meslamani J, Zhou MM
Biochimica et biophysica acta1839(8)676-85(2014 Aug)

Structural and functional insight into TAF1-TAF7, a subcomplex of transcription factor II D.
Bhattacharya S, Lou X, Hwang P, Rajashankar KR, Wang X, Gustafsson J?, Fletterick RJ, Jacobson RH, Webb P
Proceedings of the National Academy of Sciences of the United States of America111(25)9103-8(2014 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the distribution of N-TAF1 protein could represent a key molecular characteristic contributing to the pattern of striatal degeneration in DYT3 dystonia.
Title: Identification and localization of a neuron-specific isoform of TAF1 in rat brain: implications for neuropathology of DYT3 dystonia.

The following Taf1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Taf1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa39829	NM_001191723.1 Latest version!	Rattus norvegicus TATA-box binding protein associated factor 1 (Taf1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$951.30 $1359.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Taf1 ( NM_001191723.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001178652.1 Rattus norvegicus TATA-box binding protein associated factor 1 (Taf1), mRNA.

Price & Availability↑

CloneID	ORa39829
Clone ID Related Accession (Same CDS sequence)	NM_001191723.1
Accession Version	NM_001191723.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5682bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Rattus norvegicus(Norway rat)
Product	transcription initiation factor TFIID subunit 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AAHX01111635.1 and AAHX01111636.1. On Jul 17, 2010 this sequence version replaced XM_228551.5. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGGGCCAG GGTGGGCTGG ACTGCTGCCC GAAGACGGTT CTGGTAGCCC TTCCGCCGTC 
ATGTCAGACA CAGACAGCGA TGAAGATTCT GCTGGTGGAG GCCCGTTTTC TTTGACTGGG 
TTCCTGTTCG GCAACATAAA TGGAGCAGGG CAGCTGGAGG GTGAAAGCGT CTTGGACGAT 
GAGTGCAAGA AGCATCTTGC AGGCTTGGGG GCATTGGGCC TTGGTAGCCT GATCACTGAA 
CTCACAGCAA ATGAAGAATT GTCTGGGACT GATGGTACCC TGGTAAATGA TGAAGGATGG 
ATTAGGAGTA GAGAAGATGC TGTGGACTAC TCAGACATCA ACGAGGTGGC AGAAGATGAA 
AGTCGAAGAT ATCAGCAGAC AATGGGGAGC TTGCAACCCC TTTGCCACAC AGATTATGAT 
GAAGATGACT ATGATGCTGA TTGTGAAGAT ATTGATTGCA AATTGATGCC TCCCCCACCT 
CCACCCCCAG GACCAGTGAA GAAAGAGAGG GACCAAGATG GTATTACTGG TGTGTCTGAA 
GATGGAGAAG GCATCATCTT GCCCTCCATC ATTGCCCCTT CCTCTTTGGC CTCAGAGAAA 
GTGGACTTCA GTAGTTCCTC TGACTCAGAA TCTGAGATGG GACCTCAGGA AGCAACACAG 
TCAGAATCTA AGGATGGAAA GCTGACCCTA CCATTGGCTG GGATTATGCA GCATGATGCC 
ACCAAGCTGT TGCCAAGTGT CACAGAACTT TTTCCAGAAT TTAGACCTGG AAAGGTGTTA 
CGCTTTTTAC GGCTTTTTGG ACCAGGGAAG AATGTCCCAT CTGTTTGGAG GAGTGCTCGG 
AGAAAGAGGA AAAAGAAGCA CCGTGAACTT ATACAGGAAG AGCAGATCCA GGAAGAGGAG 
TGTTCAGTAG AATTAGAAGT CAACCAGAAA TCTCTGTGGA ACTATGACTA TGCTCCACCA 
CCACTTCCAG AGCAGTGTCT CTCTGATGAT GAAATCACAA TGATGGCTCC TGTGGAGTCC 
AAGTTTTCCC AGTCAACTGG AGATACAGAT AAAGTAATGG ATACCAAACC AAGAGTGGCA 
GAATGGCGTT ATGGACCTGC CCGGCTATGG TATGATATGC TAGGTGTTCC TGAAGATGGC 
AGTGGCTTTG ACTATGGCTT CAAAATGAAG AAGACTGAAC ATGACTCTAC AATGAAATAT 
AACATAATGA AGAAACTAAG AAAACTTGAG GAAAACAATG GCGTTGATCT TCTGGCAGAT 
GAAAACTTCC TAATGGTGAC ACAACTGCAT TGGGAAGATG ATATCATCTG GGATGGGGAG 
GATGTCAAAC ACAAAGGAAC AAAACCTCAG CGTGCAAGTT TGGCAGGTTG GCTTCCCTCC 
AGTATGACTA GGAATGCCAT GGCCTACAAT GTTCAGCAAG GTTTTACAGC TACATTGGAT 
GATGATAAAC CATGGTACTC CATTTTCCCC ATTGATAATG AAGATCTGGT ATATGGACGT 
TGGGAGGACA ATATCATTTG GGATGCTCAG AACATGCCTA GGATTTTGGA GCCTCCTGTT 
TTGACACTTG ATCCCAATGA TGAGAACTTG ATTTTGGAGA TCCCCGATGA GAAGGAAGAA 
GCTACTTCTA ATTCCCCTTC TAAGGAGAAT AAGAAAGAAT CATCTCTGAA GAAGAGTCGA 
ATTCTCTTGG GAAAAACAGG AGTTATCAAG GAAGAGCCAC AGCAGAACAT GTCTCAGCCA 
GAAGTGAAAG ATCCATGGAA TCTCTCCAAT GATGAGTATT ACTATCCCAA GCAACAGGGT 
CTTCGAGGTA CTTTCGGAGG GAATATTATC CAGCACTCAA TTCCAGCTGT AGAATTACGG 
CAGCCCTTCT TTCCCACCCA CATGGGACCC ATCAAACTCC GGCAGTTCCA TCGCCCACCT 
CTAAAAAAGT ACTCCTTTGG GGCACTATCT CAGCCAGGCC CACACTCAGT CCAGCCTTTG 
TTGAAGCATA TCAAAAAGAA GGCCAAGATG AGAGAACAAG AGAGACAAGC CTCGGGTGGT 
GGAGAGATGT TTTTTATGCG TACACCTCAG GACCTTACAG GCAAAGATGG AGACCTTATT 
CTTGCTGAAT ACAGTGAAGA AAATGGACCA TTAATGATGC AAGTTGGCAT GGCAACTAAG 
ATAAAAAACT ACTATAAACG GAAACCTGGA AAAGATCCTG GAGCCCCAGA TTGCAAATAT 
GGAGAAACTG TTTATTGTCA TACATCACCT TTCCTGGGTT CTCTTCATCC TGGCCAGTTA 
CTGCAGGCAT TTGAAAACAA CCTTTTTCGT GCTCCAATTT ATCTTCATAA GATGCCAGAG 
TCTGACTTCC TGATCATTCG CACAAGGCAG GGTTACTATA TTCGAGAATT GGTGGATATT 
TTTGTTGTGG GCCAGCAGTG TCCCTTGTTT GAAGTTCCTG GTCCTAATTC CAAAAGGGCC 
AATACACACA TCAGAGACTT TCTGCAGGTT TTTATTTACC GGCTCTTTTG GAAGAGTAAA 
GATAGGCCAC GGAGGATACG GATGGAAGAT ATAAAGAAAG CCTTTCCTTC ACATTCAGAA 
AGCAGCATCC GGAAGAGGCT AAAGCTCTGT GCTGACTTCA AACGTACAGG GATGGATTCA 
AACTGGTGGG TGCTGAAGTC TGATTTTCGT TTACCAACGG AAGAGGAGAT CAGAGCTATG 
GTCTCTCCAG AACAGTGCTG TGCTTATTAT AGCATGATAG CTGCAGAACA GAGACTAAAG 
GATGCTGGCT ATGGAGAGAA GTCCTTTTTT GCTCCTGAGG AAGAAAATGA AGAAGATTTC 
CAGATGAAGA TTGATGATGA AGTTCGTACT GCTCCTTGGA ATACTACAAG GGCTTTCATT 
GCTGCCATGA AGGGCAAATG TCTCCTGGAG GTGACTGGAG TAGCAGATCC TACAGGTTGT 
GGTGAAGGGT TCTCCTATGT GAAGATTCCA AACAAACCAA CACAGCAGAA GGATGATAAG 
GAGCCTCAGC CAGTGAAGAA AACAGTCACA GGAACAGATG CAGACCTTCG TCGCCTATCT 
TTGAAAAATG CCAAGCAACT TCTTCGTAAA TTTGGTGTGC CTGAGGAAGA GATTAAAAAG 
TTGTCCCGCT GGGAAGTTAT TGATGTGGTA CGCACAATGT CAACAGAACA GGCTCGTTCC 
GGAGAGGGGC CCATGAGTAA ATTTGCTCGT GGATCAAGGT TTTCTGTGGC TGAGCATCAA 
GAACGTTACA AAGAGGAATG TCAGCGCATC TTTGACCTAC AGAACAAGGT TTTGTCTTCA 
ACAGAGGTCT TATCAACTGA CACAGACAGC AGCTCAGCTG AAGACAGTGA CTTTGAAGAA 
ATGGGAAAAA ACATTGAGAA TATGCTGCAG AACAAGAAAA CAAGCTCTCA GCTGTCCAGG 
GAACGGGAGG AGCAGGAACG AAAGGAACTC CAGCGGATGC TACTGGCAGC AGGCTCGGCA 
GCAGGAGGAA ACAACCACAG AGATGATGAC ACAGCCTCGG TGACTAGCCT TAACTCTTCT 
GCCACTGGCC GCTGTCTCAA GATTTATCGA ACATTTCGAG ATGAGGAGGG GAAGGAATAT 
GTTCGTTGTG AGACAGTCCG AAAAGCAGCT GTTATTGATG CTTATGTACG CATACGGACC 
ACAAAAGATG AAGAATTCAT TCGAAAATTT GCCCTTTTTG ATGAGCAACA CCGAGAAGAG 
ATGAGAAAAG AACGGCGGAG GATTCAGGAG CAACTGAGGA GACTTAAACG AAACCAGGAA 
AAGGAGAAAC TGAAGGGTCC TCCTGAGAAA AAGCCCAAAA AGATGAAGGA ACGTCCTGAC 
TTAAAACTAA AATGTGGAGC ATGTGGTGCA ATTGGACACA TGAGGACAAA TAAATTCTGC 
CCTCTTTATT ATCAAACAAA TGCACCACCT TCTAATCCTG TTGCAATGAC AGAGGAACAG 
GAAGAAGAGC TGGAAAAGAC AGTCATTCAC AATGATAATG AAGAACTTAT CAAGGTCGAA 
GGGACCAAGA TCGTTTTGGG AAAACAGCTA ATTGAGAGTG CGGATGAAGT ACGCAGAAAA 
TCTCTGGTTC TGAAGTTCCC TAAACAACAA CTTCCTCCCA AGAAAAAGCG TCGGGTTGGA 
ACCACTGTTC ACTGTGACTA TTTGAATAGA CCTCATAAAT CCATCCACCG ACGCCGGACA 
GACCCTATGG TGACACTGTC TTCTATCTTG GAATCTATTA TCAATGACAT GAGAGATCTT 
CCAAATACAT ACCCTTTCCA TACTCCAGTT AATGCAAAAG TTGTAAAGGA TTACTACAAA 
ATCATCACTC GGCCAATGGA TCTACAAACA CTCCGTGAAA ATGTGCGCAA ACGTCTTTAT 
CCATCTCGAG AAGAATTCAG AGAACATTTG GAATTAATTG TGAAAAATAG TGCAACTTAT 
AATGGGCCAA AACATTCACT GACTCAGATT TCTCAATCCA TGCTGGATCT CTGTGATGAA 
AAACTCAAAG AGAAAGAGGA TAAGTTGGCA CGTTTAGAGA AAGCTATCAA CCCCTTGCTT 
GATGATGATG ATCAAGTAGC ATTTTCTTTT ATTCTGGATA ACATTGTCAC TCAGAAAATG 
ATGGCAGTTC CAGATTCTTG GCCATTTCAT CACCCAGTTA ATAAGAAGTT TGTTCCAGAT 
TATTACAAAG TGATTGTCAA TCCAATGGAT TTGGAGACTA TACGTAAGAA TATCTCCAAG 
CACAAATACC AGAGTCGAGA GAGCTTTTTA GATGATGTAA ACCTGATTCT GGCCAACAGT 
GTTAAGTACA ATGGGCCTGA GAGTCAGTAT ACTAAGACTG CTCAGGAGAT TGTGAACGTT 
TGTCACCAGA CATTAACTGA GTATGATGAA CATTTGACTC AACTTGAGAA AGATATTTGT 
ACAGCTAAAG AAGCAGCTCT GGAGGAAGCA GAATTAGAAA GTCTAGACCC AATGACTCCA 
GGACCTTATA CCCCTCAGGC TAAGCCTCCT GATTTATATG ATAACAGCAC ATCCCTCAGT 
GTTTCTCGAG ATGCTTCGGT GTATCAAGAT GAGAGCAATC TGTCTGTCTT GGATATTCCC 
AGTGCTACTT CAGAAAAGCA GCTAACACAG GAAGGTGGAG ACGGAGATGG TGATCTTGCA 
GATGAAGAGG AAGGAACTGT ACAACAGCCC CAAGCCAGTG TCCTGTATGA GGATTTGCTT 
ATGTCTGAAG GTGAAGATGA TGAAGAAGAT GCTGGGAGTG ATGAAGAAGG AGATAACCCT 
TTCTCTGCTA TTCAGCTAAG TGAAAGTGGA AGTGACTCTG ATGTGGAATC TGGCAGCATA 
AGACCCAAAC AGCCCCGCAT GCTTCAAGAG AATACAAGGA TGGGCATGGA AAATGAAGAA 
AGCATGATGT CCTATGAGGG AGATGGTGGG GAGGCTTCCC GTGGTTTGGA GGATAGCAAC 
ATCAGTTATG GGAGCTATGA GGAGCCTGAT CCCAAGTCGA ACACCCAGGA TACAAGCTTC 
AGCAGCATCG GTGGGTATGA GGTATCAGAG GAGGAAGAAG ATGAGGAAGA GCAGCGCTCT 
GGGCCCAGCG TTCTAAGCCA GGTCCAACTC TCAGAGGACG AGGAGGACAG TGAGGATCTC 
CACTCCATTG CTGGAGACAG TGACTTGGAC TCTGATGAAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001178652.1
CDS	13..5694
Translation	MGPGWAGLLPEDGSGSPSAVMSDTDSDEDSAGGGPFSLTGFLFGNINGAGQLEGESVLDDECKKHLAGLGALGLGSLITELTANEELSGTDGTLVNDEGWIRSREDAVDYSDINEVAEDESRRYQQTMGSLQPLCHTDYDEDDYDADCEDIDCKLMPPPPPPPGPVKKERDQDGITGVSEDGEGIILPSIIAPSSLASEKVDFSSSSDSESEMGPQEATQSESKDGKLTLPLAGIMQHDATKLLPSVTELFPEFRPGKVLRFLRLFGPGKNVPSVWRSARRKRKKKHRELIQEEQIQEEECSVELEVNQKSLWNYDYAPPPLPEQCLSDDEITMMAPVESKFSQSTGDTDKVMDTKPRVAEWRYGPARLWYDMLGVPEDGSGFDYGFKMKKTEHDSTMKYNIMKKLRKLEENNGVDLLADENFLMVTQLHWEDDIIWDGEDVKHKGTKPQRASLAGWLPSSMTRNAMAYNVQQGFTATLDDDKPWYSIFPIDNEDLVYGRWEDNIIWDAQNMPRILEPPVLTLDPNDENLILEIPDEKEEATSNSPSKENKKESSLKKSRILLGKTGVIKEEPQQNMSQPEVKDPWNLSNDEYYYPKQQGLRGTFGGNIIQHSIPAVELRQPFFPTHMGPIKLRQFHRPPLKKYSFGALSQPGPHSVQPLLKHIKKKAKMREQERQASGGGEMFFMRTPQDLTGKDGDLILAEYSEENGPLMMQVGMATKIKNYYKRKPGKDPGAPDCKYGETVYCHTSPFLGSLHPGQLLQAFENNLFRAPIYLHKMPESDFLIIRTRQGYYIRELVDIFVVGQQCPLFEVPGPNSKRANTHIRDFLQVFIYRLFWKSKDRPRRIRMEDIKKAFPSHSESSIRKRLKLCADFKRTGMDSNWWVLKSDFRLPTEEEIRAMVSPEQCCAYYSMIAAEQRLKDAGYGEKSFFAPEEENEEDFQMKIDDEVRTAPWNTTRAFIAAMKGKCLLEVTGVADPTGCGEGFSYVKIPNKPTQQKDDKEPQPVKKTVTGTDADLRRLSLKNAKQLLRKFGVPEEEIKKLSRWEVIDVVRTMSTEQARSGEGPMSKFARGSRFSVAEHQERYKEECQRIFDLQNKVLSSTEVLSTDTDSSSAEDSDFEEMGKNIENMLQNKKTSSQLSREREEQERKELQRMLLAAGSAAGGNNHRDDDTASVTSLNSSATGRCLKIYRTFRDEEGKEYVRCETVRKAAVIDAYVRIRTTKDEEFIRKFALFDEQHREEMRKERRRIQEQLRRLKRNQEKEKLKGPPEKKPKKMKERPDLKLKCGACGAIGHMRTNKFCPLYYQTNAPPSNPVAMTEEQEEELEKTVIHNDNEELIKVEGTKIVLGKQLIESADEVRRKSLVLKFPKQQLPPKKKRRVGTTVHCDYLNRPHKSIHRRRTDPMVTLSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKEDKLARLEKAINPLLDDDDQVAFSFILDNIVTQKMMAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYTKTAQEIVNVCHQTLTEYDEHLTQLEKDICTAKEAALEEAELESLDPMTPGPYTPQAKPPDLYDNSTSLSVSRDASVYQDESNLSVLDIPSATSEKQLTQEGGDGDGDLADEEEGTVQQPQASVLYEDLLMSEGEDDEEDAGSDEEGDNPFSAIQLSESGSDSDVESGSIRPKQPRMLQENTRMGMENEESMMSYEGDGGEASRGLEDSNISYGSYEEPDPKSNTQDTSFSSIGGYEVSEEEEDEEEQRSGPSVLSQVQLSEDEEDSEDLHSIAGDSDLDSDE

Target ORF information:

RefSeq Version	NM_001191723.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus TATA-box binding protein associated factor 1 (Taf1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001191723.1

ORF Insert Sequence:

ATGGGGCCAG GGTGGGCTGG ACTGCTGCCC GAAGACGGTT CTGGTAGCCC TTCCGCCGTC 
ATGTCAGACA CAGACAGCGA TGAAGATTCT GCTGGTGGAG GCCCGTTTTC TTTGACTGGG 
TTCCTGTTCG GCAACATAAA TGGAGCAGGG CAGCTGGAGG GTGAAAGCGT CTTGGACGAT 
GAGTGCAAGA AGCATCTTGC AGGCTTGGGG GCATTGGGCC TTGGTAGCCT GATCACTGAA 
CTCACAGCAA ATGAAGAATT GTCTGGGACT GATGGTACCC TGGTAAATGA TGAAGGATGG 
ATTAGGAGTA GAGAAGATGC TGTGGACTAC TCAGACATCA ACGAGGTGGC AGAAGATGAA 
AGTCGAAGAT ATCAGCAGAC AATGGGGAGC TTGCAACCCC TTTGCCACAC AGATTATGAT 
GAAGATGACT ATGATGCTGA TTGTGAAGAT ATTGATTGCA AATTGATGCC TCCCCCACCT 
CCACCCCCAG GACCAGTGAA GAAAGAGAGG GACCAAGATG GTATTACTGG TGTGTCTGAA 
GATGGAGAAG GCATCATCTT GCCCTCCATC ATTGCCCCTT CCTCTTTGGC CTCAGAGAAA 
GTGGACTTCA GTAGTTCCTC TGACTCAGAA TCTGAGATGG GACCTCAGGA AGCAACACAG 
TCAGAATCTA AGGATGGAAA GCTGACCCTA CCATTGGCTG GGATTATGCA GCATGATGCC 
ACCAAGCTGT TGCCAAGTGT CACAGAACTT TTTCCAGAAT TTAGACCTGG AAAGGTGTTA 
CGCTTTTTAC GGCTTTTTGG ACCAGGGAAG AATGTCCCAT CTGTTTGGAG GAGTGCTCGG 
AGAAAGAGGA AAAAGAAGCA CCGTGAACTT ATACAGGAAG AGCAGATCCA GGAAGAGGAG 
TGTTCAGTAG AATTAGAAGT CAACCAGAAA TCTCTGTGGA ACTATGACTA TGCTCCACCA 
CCACTTCCAG AGCAGTGTCT CTCTGATGAT GAAATCACAA TGATGGCTCC TGTGGAGTCC 
AAGTTTTCCC AGTCAACTGG AGATACAGAT AAAGTAATGG ATACCAAACC AAGAGTGGCA 
GAATGGCGTT ATGGACCTGC CCGGCTATGG TATGATATGC TAGGTGTTCC TGAAGATGGC 
AGTGGCTTTG ACTATGGCTT CAAAATGAAG AAGACTGAAC ATGACTCTAC AATGAAATAT 
AACATAATGA AGAAACTAAG AAAACTTGAG GAAAACAATG GCGTTGATCT TCTGGCAGAT 
GAAAACTTCC TAATGGTGAC ACAACTGCAT TGGGAAGATG ATATCATCTG GGATGGGGAG 
GATGTCAAAC ACAAAGGAAC AAAACCTCAG CGTGCAAGTT TGGCAGGTTG GCTTCCCTCC 
AGTATGACTA GGAATGCCAT GGCCTACAAT GTTCAGCAAG GTTTTACAGC TACATTGGAT 
GATGATAAAC CATGGTACTC CATTTTCCCC ATTGATAATG AAGATCTGGT ATATGGACGT 
TGGGAGGACA ATATCATTTG GGATGCTCAG AACATGCCTA GGATTTTGGA GCCTCCTGTT 
TTGACACTTG ATCCCAATGA TGAGAACTTG ATTTTGGAGA TCCCCGATGA GAAGGAAGAA 
GCTACTTCTA ATTCCCCTTC TAAGGAGAAT AAGAAAGAAT CATCTCTGAA GAAGAGTCGA 
ATTCTCTTGG GAAAAACAGG AGTTATCAAG GAAGAGCCAC AGCAGAACAT GTCTCAGCCA 
GAAGTGAAAG ATCCATGGAA TCTCTCCAAT GATGAGTATT ACTATCCCAA GCAACAGGGT 
CTTCGAGGTA CTTTCGGAGG GAATATTATC CAGCACTCAA TTCCAGCTGT AGAATTACGG 
CAGCCCTTCT TTCCCACCCA CATGGGACCC ATCAAACTCC GGCAGTTCCA TCGCCCACCT 
CTAAAAAAGT ACTCCTTTGG GGCACTATCT CAGCCAGGCC CACACTCAGT CCAGCCTTTG 
TTGAAGCATA TCAAAAAGAA GGCCAAGATG AGAGAACAAG AGAGACAAGC CTCGGGTGGT 
GGAGAGATGT TTTTTATGCG TACACCTCAG GACCTTACAG GCAAAGATGG AGACCTTATT 
CTTGCTGAAT ACAGTGAAGA AAATGGACCA TTAATGATGC AAGTTGGCAT GGCAACTAAG 
ATAAAAAACT ACTATAAACG GAAACCTGGA AAAGATCCTG GAGCCCCAGA TTGCAAATAT 
GGAGAAACTG TTTATTGTCA TACATCACCT TTCCTGGGTT CTCTTCATCC TGGCCAGTTA 
CTGCAGGCAT TTGAAAACAA CCTTTTTCGT GCTCCAATTT ATCTTCATAA GATGCCAGAG 
TCTGACTTCC TGATCATTCG CACAAGGCAG GGTTACTATA TTCGAGAATT GGTGGATATT 
TTTGTTGTGG GCCAGCAGTG TCCCTTGTTT GAAGTTCCTG GTCCTAATTC CAAAAGGGCC 
AATACACACA TCAGAGACTT TCTGCAGGTT TTTATTTACC GGCTCTTTTG GAAGAGTAAA 
GATAGGCCAC GGAGGATACG GATGGAAGAT ATAAAGAAAG CCTTTCCTTC ACATTCAGAA 
AGCAGCATCC GGAAGAGGCT AAAGCTCTGT GCTGACTTCA AACGTACAGG GATGGATTCA 
AACTGGTGGG TGCTGAAGTC TGATTTTCGT TTACCAACGG AAGAGGAGAT CAGAGCTATG 
GTCTCTCCAG AACAGTGCTG TGCTTATTAT AGCATGATAG CTGCAGAACA GAGACTAAAG 
GATGCTGGCT ATGGAGAGAA GTCCTTTTTT GCTCCTGAGG AAGAAAATGA AGAAGATTTC 
CAGATGAAGA TTGATGATGA AGTTCGTACT GCTCCTTGGA ATACTACAAG GGCTTTCATT 
GCTGCCATGA AGGGCAAATG TCTCCTGGAG GTGACTGGAG TAGCAGATCC TACAGGTTGT 
GGTGAAGGGT TCTCCTATGT GAAGATTCCA AACAAACCAA CACAGCAGAA GGATGATAAG 
GAGCCTCAGC CAGTGAAGAA AACAGTCACA GGAACAGATG CAGACCTTCG TCGCCTATCT 
TTGAAAAATG CCAAGCAACT TCTTCGTAAA TTTGGTGTGC CTGAGGAAGA GATTAAAAAG 
TTGTCCCGCT GGGAAGTTAT TGATGTGGTA CGCACAATGT CAACAGAACA GGCTCGTTCC 
GGAGAGGGGC CCATGAGTAA ATTTGCTCGT GGATCAAGGT TTTCTGTGGC TGAGCATCAA 
GAACGTTACA AAGAGGAATG TCAGCGCATC TTTGACCTAC AGAACAAGGT TTTGTCTTCA 
ACAGAGGTCT TATCAACTGA CACAGACAGC AGCTCAGCTG AAGACAGTGA CTTTGAAGAA 
ATGGGAAAAA ACATTGAGAA TATGCTGCAG AACAAGAAAA CAAGCTCTCA GCTGTCCAGG 
GAACGGGAGG AGCAGGAACG AAAGGAACTC CAGCGGATGC TACTGGCAGC AGGCTCGGCA 
GCAGGAGGAA ACAACCACAG AGATGATGAC ACAGCCTCGG TGACTAGCCT TAACTCTTCT 
GCCACTGGCC GCTGTCTCAA GATTTATCGA ACATTTCGAG ATGAGGAGGG GAAGGAATAT 
GTTCGTTGTG AGACAGTCCG AAAAGCAGCT GTTATTGATG CTTATGTACG CATACGGACC 
ACAAAAGATG AAGAATTCAT TCGAAAATTT GCCCTTTTTG ATGAGCAACA CCGAGAAGAG 
ATGAGAAAAG AACGGCGGAG GATTCAGGAG CAACTGAGGA GACTTAAACG AAACCAGGAA 
AAGGAGAAAC TGAAGGGTCC TCCTGAGAAA AAGCCCAAAA AGATGAAGGA ACGTCCTGAC 
TTAAAACTAA AATGTGGAGC ATGTGGTGCA ATTGGACACA TGAGGACAAA TAAATTCTGC 
CCTCTTTATT ATCAAACAAA TGCACCACCT TCTAATCCTG TTGCAATGAC AGAGGAACAG 
GAAGAAGAGC TGGAAAAGAC AGTCATTCAC AATGATAATG AAGAACTTAT CAAGGTCGAA 
GGGACCAAGA TCGTTTTGGG AAAACAGCTA ATTGAGAGTG CGGATGAAGT ACGCAGAAAA 
TCTCTGGTTC TGAAGTTCCC TAAACAACAA CTTCCTCCCA AGAAAAAGCG TCGGGTTGGA 
ACCACTGTTC ACTGTGACTA TTTGAATAGA CCTCATAAAT CCATCCACCG ACGCCGGACA 
GACCCTATGG TGACACTGTC TTCTATCTTG GAATCTATTA TCAATGACAT GAGAGATCTT 
CCAAATACAT ACCCTTTCCA TACTCCAGTT AATGCAAAAG TTGTAAAGGA TTACTACAAA 
ATCATCACTC GGCCAATGGA TCTACAAACA CTCCGTGAAA ATGTGCGCAA ACGTCTTTAT 
CCATCTCGAG AAGAATTCAG AGAACATTTG GAATTAATTG TGAAAAATAG TGCAACTTAT 
AATGGGCCAA AACATTCACT GACTCAGATT TCTCAATCCA TGCTGGATCT CTGTGATGAA 
AAACTCAAAG AGAAAGAGGA TAAGTTGGCA CGTTTAGAGA AAGCTATCAA CCCCTTGCTT 
GATGATGATG ATCAAGTAGC ATTTTCTTTT ATTCTGGATA ACATTGTCAC TCAGAAAATG 
ATGGCAGTTC CAGATTCTTG GCCATTTCAT CACCCAGTTA ATAAGAAGTT TGTTCCAGAT 
TATTACAAAG TGATTGTCAA TCCAATGGAT TTGGAGACTA TACGTAAGAA TATCTCCAAG 
CACAAATACC AGAGTCGAGA GAGCTTTTTA GATGATGTAA ACCTGATTCT GGCCAACAGT 
GTTAAGTACA ATGGGCCTGA GAGTCAGTAT ACTAAGACTG CTCAGGAGAT TGTGAACGTT 
TGTCACCAGA CATTAACTGA GTATGATGAA CATTTGACTC AACTTGAGAA AGATATTTGT 
ACAGCTAAAG AAGCAGCTCT GGAGGAAGCA GAATTAGAAA GTCTAGACCC AATGACTCCA 
GGACCTTATA CCCCTCAGGC TAAGCCTCCT GATTTATATG ATAACAGCAC ATCCCTCAGT 
GTTTCTCGAG ATGCTTCGGT GTATCAAGAT GAGAGCAATC TGTCTGTCTT GGATATTCCC 
AGTGCTACTT CAGAAAAGCA GCTAACACAG GAAGGTGGAG ACGGAGATGG TGATCTTGCA 
GATGAAGAGG AAGGAACTGT ACAACAGCCC CAAGCCAGTG TCCTGTATGA GGATTTGCTT 
ATGTCTGAAG GTGAAGATGA TGAAGAAGAT GCTGGGAGTG ATGAAGAAGG AGATAACCCT 
TTCTCTGCTA TTCAGCTAAG TGAAAGTGGA AGTGACTCTG ATGTGGAATC TGGCAGCATA 
AGACCCAAAC AGCCCCGCAT GCTTCAAGAG AATACAAGGA TGGGCATGGA AAATGAAGAA 
AGCATGATGT CCTATGAGGG AGATGGTGGG GAGGCTTCCC GTGGTTTGGA GGATAGCAAC 
ATCAGTTATG GGAGCTATGA GGAGCCTGAT CCCAAGTCGA ACACCCAGGA TACAAGCTTC 
AGCAGCATCG GTGGGTATGA GGTATCAGAG GAGGAAGAAG ATGAGGAAGA GCAGCGCTCT 
GGGCCCAGCG TTCTAAGCCA GGTCCAACTC TCAGAGGACG AGGAGGACAG TGAGGATCTC 
CACTCCATTG CTGGAGACAG TGACTTGGAC TCTGATGAAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Structure of promoter-bound TFIID and model of human pre-initiation complex assembly.
Nature531(7596)604-9(2016 03)
Louder RK,He Y,L?pez-Blanco JR,Fang J,Chac?n P,Nogales E

TAF1 Variants Are Associated with Dysmorphic Features, Intellectual Disability, and Neurological Manifestations.
American journal of human genetics97(6)922-32(2015 Dec)
O'Rawe JA,Wu Y,D?rfel MJ,Rope AF,Au PY,Parboosingh JS,Moon S,Kousi M,Kosma K,Smith CS,Tzetis M,Schuette JL,Hufnagel RB,Prada CE,Martinez F,Orellana C,Crain J,Caro-Llopis A,Oltra S,Monfort S,Jim?nez-Barr?n LT,Swensen J,Ellingwood S,Smith R,Fang H,Ospina S,Stegmann S,Den Hollander N,Mittelman D,Highnam G,Robison R,Yang E,Faivre L,Roubertie A,Rivi?re JB,Monaghan KG,Wang K,Davis EE,Katsanis N,Kalscheuer VM,Wang EH,Metcalfe K,Kleefstra T,Innes AM,Kitsiou-Tzeli S,Rosello M,Keegan CE,Lyon GJ

Crystal structure of a TAF1-TAF7 complex in human transcription factor IID reveals a promoter binding module.
Cell research24(12)1433-44(2014 Dec)
Wang H,Curran EC,Hinds TR,Wang EH,Zheng N

The bromodomain: from epigenome reader to druggable target.
Biochimica et biophysica acta1839(8)676-85(2014 Aug)
Sanchez R,Meslamani J,Zhou MM

Structural and functional insight into TAF1-TAF7, a subcomplex of transcription factor II D.
Proceedings of the National Academy of Sciences of the United States of America111(25)9103-8(2014 Jun)
Bhattacharya S,Lou X,Hwang P,Rajashankar KR,Wang X,Gustafsson J?,Fletterick RJ,Jacobson RH,Webb P

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Taf1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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