Epha4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Epha4
Entrez Gene ID	316539
Full Name	Eph receptor A4
Synonyms	RGD1560587
General protein information	Preferred Names Eph receptor A4 Names ephrin type-A receptor 4
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 9 Map Location: 9q33

mRNA and Protein(s)

mRNA	Protein	Name
XM_008767249.2	XP_008765471.1	ephrin type-A receptor 4 isoform X1
NM_001162411.1	NP_001155883.1	ephrin type-A receptor 4 precursor

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	epha4	NP_001135575.1
Pan troglodytes (chimpanzee)	EPHA4	XP_001164828.2
	EPHA4	XP_001106493.1
Danio rerio (zebrafish)	epha4a	NP_001005919.1
Caenorhabditis elegans (roundworm)	vab-1	NP_494806.1
Canis lupus familiaris (dog)	EPHA4	XP_005640771.1
Mus musculus (house mouse)	Epha4	NP_031962.2
Gallus gallus (chicken)	EPHA4	NP_990112.1
Homo sapiens (human)	EPHA4	NP_004429.1
Rattus norvegicus (Norway rat)	Epha4	NP_001155883.1

Gene Ontology
Bibliography

Related articles in PubMed

Ephrin-A1-EphA4 signaling negatively regulates myelination in the central nervous system.
Harboe M, Torvund-Jensen J, Kjaer-Sorensen K, Laursen LS
Glia(2018 Jan)

EphrinA4 mimetic peptide targeted to EphA binding site impairs the formation of long-term fear memory in lateral amygdala.
Dines M, Lamprecht R
Translational psychiatry4e450(2014 Sep)

Nephric duct insertion requires EphA4/EphA7 signaling from the pericloacal mesenchyme.
Weiss AC, Airik R, Bohnenpoll T, Greulich F, Foik A, Trowe MO, Rudat C, Costantini F, Adams RH, Kispert A
Development (Cambridge, England)141(17)3420-30(2014 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

EphrinA4 is involved in regulation of neuronal morphogenesis.
Title: EphrinA4 mimetic peptide targeted to EphA binding site impairs the formation of long-term fear memory in lateral amygdala.

EphA4 mediates the inhibitory effect on Schwann cell migration, and EphA4 knock-down can strongly increase Schwann cell migration and peripheral nerve regeneration.
Title: Inhibition of EphA4 expression promotes Schwann cell migration and peripheral nerve regeneration.

The kinase activity of EphA4, via activation of downstream Cdk5 activity, mediates the scaling-down of excitatory synaptic strength.
Title: The kinase activity of EphA4 mediates homeostatic scaling-down of synaptic strength via activation of Cdk5.

Blocking ephrinA3/EphA4 interaction by EphA4-Fc, an inhibitor of EphA4, attenuated apoptotic neuronal cell death, likely through the inhibition of caspase-3 activation
Title: Inhibition of EphA4 signaling after ischemia-reperfusion reduces apoptosis of CA1 pyramidal neurons.

These findings suggest the involvement of cell-cell EphA4 and ephrin-B2 signaling in establishing order in the developing inferior colliculus
Title: EphA4 and ephrin-B2 expression patterns during inferior colliculus projection shaping prior to experience.

The following Epha4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Epha4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa04661	NM_001162411.1 Latest version!	Rattus norvegicus Eph receptor A4 (Epha4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
ORa47549	XM_008767249.2 Latest version!	Rattus norvegicus Eph receptor A4 (Epha4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Epha4 ( NM_001162411.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001155883.1 Rattus norvegicus Eph receptor A4 (Epha4), mRNA.

Price & Availability↑

CloneID	ORa04661
Clone ID Related Accession (Same CDS sequence)	NM_001162411.1
Accession Version	NM_001162411.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2961bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Rattus norvegicus(Norway rat)
Product	ephrin type-A receptor 4 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07068085.1. On or before Jun 24, 2009 this sequence version replaced XR_007714.1, XM_244186.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## NMD candidate :: translation inferred from conservation ##RefSeq-Attributes-END##

ATGGCTGGGA TTTTCTATTT CATCCTCTTT TCGTTTCTCT TTGGAATTTG CGACGCTGTC 
ACCGGTTCTA GGGTATACCC GGCGAATGAA GTTACTTTAT TGGATTCCAG ATCTGTTCAG 
GGAGAGCTTG GGTGGATAGC AAGCCCTCTG GAAGGAGGGT GGGAGGAAGT AAGCATTATG 
GATGAGAAAA ATACACCGAT CCGAACCTAC CAGGTATGCA ACGTGATGGA AGCCAGTCAG 
AACAACTGGC TGCGAACTGA CTGGATCACC CGAGAAGGGG CGCAGAGGGT GTACATTGAA 
ATTAAGTTCA CTCTGAGGGA CTGCAACAGT CTTCCGGGCG TCATGGGGAC TTGCAAGGAG 
ACGTTTAACC TTTACTACTA TGAATCGGAC AACGACAAGG AGCGCTTCAT CAGAGAGAGC 
CAGTTCGGCA AGATCGACAC CATCGCAGCG GATGAGAGCT TTACACAGGT GGACATTGGG 
GACAGAATCA TGAAGCTCAA CACCGAGATC CGGGATGTAG GGCCCCTGAG CAAGAAGGGT 
TTTTACCTGG CTTTTCAGGA TGTGGGTGCT TGCATCGCCC TGGTGTCTGT TCGTGTGTTC 
TACAAGAAGT GTCCCCTCAC CGTTCGAAAT CTAGCCCAGT TCCCCGATAC CATCACTGGG 
GCTGATACCT CTTCCCTGGT GGAAGTTCGA GGCTCCTGTG TCAACAACTC AGAAGAGAAG 
GATGTGCCAA AAATGTACTG TGGGGCAGAT GGTGAATGGC TGGTACCCAT TGGCAACTGC 
CTATGCAATG CTGGGCACGA GGAGCAGAAT GGTGAATGCC AAGCTTGCAA AATTGGATAT 
TACAAAGCTC TCTCCACGGA CGCCACCTGT GCCAAGTGTC CACCGCACAG CTACTCTGTC 
TGGGAAGGAG CCACGTCCTG CACCTGTGAC CGAGGCTTTT TCAGAGCTGA CAACGATGCC 
GCGTCCATGC CCTGCACCCG CCCACCATCT GCTCCCCTCA ACTTGATTTC TAATGTCAAC 
GAGACGTCGG TGAACTTGGA ATGGAGCAGT CCTCAGAACA CAGGTGGCCG TCAGGACATT 
TCTTACAACG TGGTCTGCAA GAAATGTGGA GCTGGGGATC CCAGCAAGTG TCGACCCTGT 
GGAAGTGGAG TCCACTACAC GCCACAGCAG AATGGACTCA AGACGACCAG AGTCTCCATC 
ACTGACCTCC TAGCACACAC CAATTACACG TTTGAGATCT GGGCAGTGAA TGGCGTGTCT 
AAGTACAACC CTAGCCCAGA CCAGTCAGTG TCTGTCACAG TGACAACCAA CCAAGCAGCA 
CCATCATCCA TTGCTTTGGT CCAGGCTAAA GAAGTTACAA GATACAGTGT GGCTCTGGCT 
TGGCTGGAAC CAGATCGACC AAACGGAGTC ATCTTAGAAT ATGAAGTGAA ATATTATGAA 
AAGGATCAGA ATGAACGAAG CTATCGCATA GTTCGGACAG CTGCCAGGAA CACAGATATC 
AAAGGCCTGA ACCCTTTGAC TTCTTACGTC TTCCACGTGC GAGCCAGGAC CGCCGCTGGC 
TATGGAGACT TCAGCGAACC CTTGGAAGTC ACTACCAATA CAGTGCCTTC CCGAATCATT 
GGCGACGGGG CCAACTCTAC CGTCCTGCTG GTCTCCGTCT CTGGCAGTGT AGTACTCGTG 
GTCATTCTCA TTGCGGCATT TGTGATCAGC CGTAGACGGA GTAAGTACAG CCAAGCAAAG 
CAAGAAGCAG ATGAAGAGAA GCATTTGAAT CAAGGTGTTA GAACATACGT GGATCCCTTT 
ACATATGAAG ACCCCAACCA GGCAGTTCGA GAATTTGCCA AAGAAATCGA TGCCTCCTGC 
ATTAAAATCG AAAAGGTCAT TGGAGTTGGC GAATTTGGAG AAGTCTGCAG TGGGCGTCTC 
AAAGTGCCCG GCAAGAGAGA GATCTGTGTG GCCATCAAGA CTCTGAAAGC TGGTTATACT 
GACAAGCAGA GGAGAGACTT CCTGAGCGAG GCCAGCATCA TGGGACAGTT TGACCACCCA 
AACATAATCC ACCTGGAAGG CGTTGTCACC AAATGTAAAC CAGTAATGAT CATCACGGAG 
TACATGGAGA ACGGCTCCTT GGACGCTTTC CTCAGGAAGA ATGATGGCCG ATTTACAGTC 
ATTCAGCTGG TGGGCATGCT CCGAGGCATT GGCTCGGGGA TGAAGTACTT ATCTGATATG 
AGCTATGTGC ATCGAGACCT GGCTGCCAGG AACATTCTGG TAAACAGCAA CTTGGTCTGC 
AAGGTGTCTG ATTTCGGCAT GTCCAGGGTG CTTGAGGATG ACCCGGAAGC AGCCTATACT 
ACCAGGGGCG GCAAGATTCC CATCCGGTGG ACTGCACCAG AAGCAATTGC GTATCGTAAA 
TTTACCTCAG CCAGTGACGT CTGGAGCTAC GGAATCGTTA TGTGGGAAGT GATGTCATAT 
GGAGAGAGGC CGTACTGGGA TATGTCCAAT CAAGATGTGA TCAAAGCCAT CGAGGAAGGG 
TACCGGCTAC CCCCGCCAAT GGACTGCCCC ATTGCCCTCC ATCAGTTAAT GCTGGACTGT 
TGGCAGAAAG AGAGAAGCGA CAGGCCTAAA TTTGGGCAGA TCGTCAACAT GTTGGACAAA 
CTCATCCGCA ACCCCAACAG CCTGAAGAGG ACAGGGCCAG AGAGTTCCAG ACCAAACACA 
GCCTTGTTAG ATCCCAGCTC CCCTGAATTC TCCGCCGTAG TATCAGTGGG TGACTGGCTG 
CAGGCCATCA AAATGGACCG GTATAAGGAC AACTTCACAG CCGCCGGGTA CACGACACTA 
GAAGCTGTGG TTCACATGAG CCAGGATGAC CTGGCGCGAA TTGGCATCAC CGCAATCACG 
CACCAGAATA AGATTTTGAG CAGCGTCCAG GCGATGCGAA CCCAGATGCA GCAGATGCAT 
GGCAGGATGG TTCCTGTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001155883.1
CDS	57..3017
Translation	MAGIFYFILFSFLFGICDAVTGSRVYPANEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEASQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRESQFGKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVPKMYCGADGEWLVPIGNCLCNAGHEEQNGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVHYTPQQNGLKTTRVSITDLLAHTNYTFEIWAVNGVSKYNPSPDQSVSVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTVLLVSVSGSVVLVVILIAAFVISRRRSKYSQAKQEADEEKHLNQGVRTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGPESSRPNTALLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHMSQDDLARIGITAITHQNKILSSVQAMRTQMQQMHGRMVPV

Target ORF information:

RefSeq Version	NM_001162411.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Eph receptor A4 (Epha4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001162411.1

ORF Insert Sequence:

ATGGCTGGGA TTTTCTATTT CATCCTCTTT TCGTTTCTCT TTGGAATTTG CGACGCTGTC 
ACCGGTTCTA GGGTATACCC GGCGAATGAA GTTACTTTAT TGGATTCCAG ATCTGTTCAG 
GGAGAGCTTG GGTGGATAGC AAGCCCTCTG GAAGGAGGGT GGGAGGAAGT AAGCATTATG 
GATGAGAAAA ATACACCGAT CCGAACCTAC CAGGTATGCA ACGTGATGGA AGCCAGTCAG 
AACAACTGGC TGCGAACTGA CTGGATCACC CGAGAAGGGG CGCAGAGGGT GTACATTGAA 
ATTAAGTTCA CTCTGAGGGA CTGCAACAGT CTTCCGGGCG TCATGGGGAC TTGCAAGGAG 
ACGTTTAACC TTTACTACTA TGAATCGGAC AACGACAAGG AGCGCTTCAT CAGAGAGAGC 
CAGTTCGGCA AGATCGACAC CATCGCAGCG GATGAGAGCT TTACACAGGT GGACATTGGG 
GACAGAATCA TGAAGCTCAA CACCGAGATC CGGGATGTAG GGCCCCTGAG CAAGAAGGGT 
TTTTACCTGG CTTTTCAGGA TGTGGGTGCT TGCATCGCCC TGGTGTCTGT TCGTGTGTTC 
TACAAGAAGT GTCCCCTCAC CGTTCGAAAT CTAGCCCAGT TCCCCGATAC CATCACTGGG 
GCTGATACCT CTTCCCTGGT GGAAGTTCGA GGCTCCTGTG TCAACAACTC AGAAGAGAAG 
GATGTGCCAA AAATGTACTG TGGGGCAGAT GGTGAATGGC TGGTACCCAT TGGCAACTGC 
CTATGCAATG CTGGGCACGA GGAGCAGAAT GGTGAATGCC AAGCTTGCAA AATTGGATAT 
TACAAAGCTC TCTCCACGGA CGCCACCTGT GCCAAGTGTC CACCGCACAG CTACTCTGTC 
TGGGAAGGAG CCACGTCCTG CACCTGTGAC CGAGGCTTTT TCAGAGCTGA CAACGATGCC 
GCGTCCATGC CCTGCACCCG CCCACCATCT GCTCCCCTCA ACTTGATTTC TAATGTCAAC 
GAGACGTCGG TGAACTTGGA ATGGAGCAGT CCTCAGAACA CAGGTGGCCG TCAGGACATT 
TCTTACAACG TGGTCTGCAA GAAATGTGGA GCTGGGGATC CCAGCAAGTG TCGACCCTGT 
GGAAGTGGAG TCCACTACAC GCCACAGCAG AATGGACTCA AGACGACCAG AGTCTCCATC 
ACTGACCTCC TAGCACACAC CAATTACACG TTTGAGATCT GGGCAGTGAA TGGCGTGTCT 
AAGTACAACC CTAGCCCAGA CCAGTCAGTG TCTGTCACAG TGACAACCAA CCAAGCAGCA 
CCATCATCCA TTGCTTTGGT CCAGGCTAAA GAAGTTACAA GATACAGTGT GGCTCTGGCT 
TGGCTGGAAC CAGATCGACC AAACGGAGTC ATCTTAGAAT ATGAAGTGAA ATATTATGAA 
AAGGATCAGA ATGAACGAAG CTATCGCATA GTTCGGACAG CTGCCAGGAA CACAGATATC 
AAAGGCCTGA ACCCTTTGAC TTCTTACGTC TTCCACGTGC GAGCCAGGAC CGCCGCTGGC 
TATGGAGACT TCAGCGAACC CTTGGAAGTC ACTACCAATA CAGTGCCTTC CCGAATCATT 
GGCGACGGGG CCAACTCTAC CGTCCTGCTG GTCTCCGTCT CTGGCAGTGT AGTACTCGTG 
GTCATTCTCA TTGCGGCATT TGTGATCAGC CGTAGACGGA GTAAGTACAG CCAAGCAAAG 
CAAGAAGCAG ATGAAGAGAA GCATTTGAAT CAAGGTGTTA GAACATACGT GGATCCCTTT 
ACATATGAAG ACCCCAACCA GGCAGTTCGA GAATTTGCCA AAGAAATCGA TGCCTCCTGC 
ATTAAAATCG AAAAGGTCAT TGGAGTTGGC GAATTTGGAG AAGTCTGCAG TGGGCGTCTC 
AAAGTGCCCG GCAAGAGAGA GATCTGTGTG GCCATCAAGA CTCTGAAAGC TGGTTATACT 
GACAAGCAGA GGAGAGACTT CCTGAGCGAG GCCAGCATCA TGGGACAGTT TGACCACCCA 
AACATAATCC ACCTGGAAGG CGTTGTCACC AAATGTAAAC CAGTAATGAT CATCACGGAG 
TACATGGAGA ACGGCTCCTT GGACGCTTTC CTCAGGAAGA ATGATGGCCG ATTTACAGTC 
ATTCAGCTGG TGGGCATGCT CCGAGGCATT GGCTCGGGGA TGAAGTACTT ATCTGATATG 
AGCTATGTGC ATCGAGACCT GGCTGCCAGG AACATTCTGG TAAACAGCAA CTTGGTCTGC 
AAGGTGTCTG ATTTCGGCAT GTCCAGGGTG CTTGAGGATG ACCCGGAAGC AGCCTATACT 
ACCAGGGGCG GCAAGATTCC CATCCGGTGG ACTGCACCAG AAGCAATTGC GTATCGTAAA 
TTTACCTCAG CCAGTGACGT CTGGAGCTAC GGAATCGTTA TGTGGGAAGT GATGTCATAT 
GGAGAGAGGC CGTACTGGGA TATGTCCAAT CAAGATGTGA TCAAAGCCAT CGAGGAAGGG 
TACCGGCTAC CCCCGCCAAT GGACTGCCCC ATTGCCCTCC ATCAGTTAAT GCTGGACTGT 
TGGCAGAAAG AGAGAAGCGA CAGGCCTAAA TTTGGGCAGA TCGTCAACAT GTTGGACAAA 
CTCATCCGCA ACCCCAACAG CCTGAAGAGG ACAGGGCCAG AGAGTTCCAG ACCAAACACA 
GCCTTGTTAG ATCCCAGCTC CCCTGAATTC TCCGCCGTAG TATCAGTGGG TGACTGGCTG 
CAGGCCATCA AAATGGACCG GTATAAGGAC AACTTCACAG CCGCCGGGTA CACGACACTA 
GAAGCTGTGG TTCACATGAG CCAGGATGAC CTGGCGCGAA TTGGCATCAC CGCAATCACG 
CACCAGAATA AGATTTTGAG CAGCGTCCAG GCGATGCGAA CCCAGATGCA GCAGATGCAT 
GGCAGGATGG TTCCTGTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Epha4 ( XM_008767249.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008765471.1 Rattus norvegicus Eph receptor A4 (Epha4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa47549
Clone ID Related Accession (Same CDS sequence)	XM_008767249.2
Accession Version	XM_008767249.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2850bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	ephrin type-A receptor 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005108.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008767249.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGGGA TTTTCTATTT CATCCTCTTT TCGTTTCTCT TTGGAATTTG CGACGCTGTC 
ACCGGTTCTA GGGTATACCC GGCGAATGAA GTTACTTTAT TGGATTCCAG ATCTGTTCAG 
GGAGAGCTTG GGTGGATAGC AAGCCCTCTG GAAGGAGGGT GGGAGGAAGT AAGCATTATG 
GATGAGAAAA ATACACCGAT CCGAACCTAC CAGGTATGCA ACGTGATGGA AGCCAGTCAG 
AACAACTGGC TGCGAACTGA CTGGATCACC CGAGAAGGGG CGCAGAGGGT GTACATTGAA 
ATTAAGTTCA CTCTGAGGGA CTGCAACAGT CTTCCGGGCG TCATGGGGAC TTGCAAGGAG 
ACGTTTAACC TTTACTACTA TGAATCGGAC AACGACAAGG AGCGCTTCAT CAGAGAGAGC 
CAGTTCGGCA AGATCGACAC CATCGCAGCG GATGAGAGCT TTACACAGGT GGACATTGGG 
GACAGAATCA TGAAGCTCAA CACCGAGATC CGGGATGTAG GGCCCCTGAG CAAGAAGGGT 
TTTTACCTGG CTTTTCAGGA TGTGGGTGCT TGCATCGCCC TGGTGTCTGT TCGTGTGTTC 
TACAAGAAGT GTCCCCTCAC CGTTCGAAAT CTAGCCCAGT TCCCCGATAC CATCACTGGG 
GCTGATACCT CTTCCCTGGT GGAAGTTCGA GGCTCCTGTG TCAACAACTC AGAAGAGAAG 
GATGTGCCAA AAATGTACTG TGGGGCAGAT GGTGAATGGC TGGTACCCAT TGGCAACTGC 
CTATGCAATG CTGGGCACGA GGAGCAGAAT GGTGAATGCC AAGCTTGCAA AATTGGATAT 
TACAAAGCTC TCTCCACGGA CGCCACCTGT GCCAAGTGTC CACCGCACAG CTACTCTGTC 
TGGGAAGGAG CCACGTCCTG CACCTGTGAC CGAGGCTTTT TCAGAGCTGA CAACGATGCC 
GCGTCCATGC CCTGCACCCG CCCACCATCT GCTCCCCTCA ACTTGATTTC TAATGTCAAC 
GAGACGTCGG TGAACTTGGA ATGGAGCAGT CCTCAGAACA CAGGTGGCCG TCAGGACATT 
TCTTACAACG TGGTCTGCAA GAAATGTGGA GCTGGGGATC CCAGCAAGTG TCGACCCTGT 
GGAAGTGGAG TCCACTACAC GCCACAGCAG AATGGACTCA AGACGACCAG AGTCTCCATC 
ACTGACCTCC TAGCACACAC CAATTACACG TTTGAGATCT GGGCAGTGAA TGGCGTGTCT 
AAGTACAACC CTAGCCCAGA CCAGTCAGTG TCTGTCACAG TGACAACCAA CCAAGCAGCA 
CCATCATCCA TTGCTTTGGT CCAGGCTAAA GAAGTTACAA GATACAGTGT GGCTCTGGCT 
TGGCTGGAAC CAGATCGACC AAACGGAGTC ATCTTAGAAT ATGAAGTGAA ATATTATGAA 
AAGGATCAGA ATGAACGAAG CTATCGCATA GTTCGGACAG CTGCCAGGAA CACAGATATC 
AAAGGCCTGA ACCCTTTGAC TTCTTACGTC TTCCACGTGC GAGCCAGGAC CGCCGCTGGC 
TATGGAGACT TCAGCGAACC CTTGGAAGTC ACTACCAATA CAGTGCCTTC CCGAATCATT 
GGCGACGGGG CCAACTCTAC CGTCCTGCTG GTCTCCGTCT CTGGCAGTGT AGTACTCGTG 
GTCATTCTCA TTGCGGCATT TGTGATCAGC CGTAGACGGA GTAAGTACAG CCAAGCAAAG 
CAAGAAGCAG ATGAAGAGAA GCATTTGAAT CAAGGTGTTA GAACATACGT GGATCCCTTT 
ACATATGAAG ACCCCAACCA GGCAGTTCGA GAATTTGCCA AAGAAATCGA TGCCTCCTGC 
ATTAAAATCG AAAAGGTCAT TGGAGTTGGC GAATTTGGAG AAGTCTGCAG TGGGCGTCTC 
AAAGTGCCCG GCAAGAGAGA GATCTGTGTG GCCATCAAGA CTCTGAAAGC TGGTTATACT 
GACAAGCAGA GGAGAGACTT CCTGAGCGAG GCCAGCATCA TGGGACAGTT TGACCACCCA 
AACATAATCC ACCTGGAAGG CGTTGTCACC AAATGTAAAC CAGTAATGAT CATCACGGAG 
TACATGGAGA ACGGCTCCTT GGACGCTTTC CTCAGGAAGA ATGATGGCCG ATTTACAGTC 
ATTCAGCTGG TGGGCATGCT CCGAGGCATT GGCTCGGGGA TGAAGTACTT ATCTGATATG 
AGCTATGTGC ATCGAGACCT GGCTGCCAGG AACATTCTGG TAAACAGCAA CTTGGTCTGC 
AAGGTGTCTG ATTTCGGCAT GTCCAGGGTG CTTGAGGATG ACCCGGAAGC AGCCTATACT 
ACCAGGGGCG GCAAGATTCC CATCCGGTGG ACTGCACCAG AAGCAATTGC GTATCGTAAA 
TTTACCTCAG CCAGTGACGT CTGGAGCTAC GGAATCGTTA TGTGGGAAGT GATGTCATAT 
GGAGAGAGGC CGTACTGGGA TATGTCCAAT CAAGATGTGA TCAAAGCCAT CGAGGAAGGG 
TACCGGCTAC CCCCGCCAAT GGACTGCCCC ATTGCCCTCC ATCAGTTAAT GCTGGACTGT 
TGGCAGAAAG AGAGAAGCGA CAGGCCTAAA TTTGGGCAGA TCGTCAACAT GTTGGACAAA 
CTCATCCGCA ACCCCAACAG CCTGAAGAGG ACAGGGCCAG AGAGTTCCAG ACCAAACACA 
GCCTTGTTAG ATCCCAGCTC CCCTGAATTC TCCGCCGTAG TATCAGTGGG TGACTGGCTG 
CAGGCCATCA AAATGGACCG GTATAAGGAC AACTTCACAG CCGCCGGGTA CACGACACTA 
GAAGCTGTGG TTCACATGAG CCAGGAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008765471.1
CDS	85..2934
Translation	MAGIFYFILFSFLFGICDAVTGSRVYPANEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEASQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRESQFGKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVPKMYCGADGEWLVPIGNCLCNAGHEEQNGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVHYTPQQNGLKTTRVSITDLLAHTNYTFEIWAVNGVSKYNPSPDQSVSVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTVLLVSVSGSVVLVVILIAAFVISRRRSKYSQAKQEADEEKHLNQGVRTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGPESSRPNTALLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHMSQE

Target ORF information:

RefSeq Version	XM_008767249.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus Eph receptor A4 (Epha4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008767249.2

ORF Insert Sequence:

ATGGCTGGGA TTTTCTATTT CATCCTCTTT TCGTTTCTCT TTGGAATTTG CGACGCTGTC 
ACCGGTTCTA GGGTATACCC GGCGAATGAA GTTACTTTAT TGGATTCCAG ATCTGTTCAG 
GGAGAGCTTG GGTGGATAGC AAGCCCTCTG GAAGGAGGGT GGGAGGAAGT AAGCATTATG 
GATGAGAAAA ATACACCGAT CCGAACCTAC CAGGTATGCA ACGTGATGGA AGCCAGTCAG 
AACAACTGGC TGCGAACTGA CTGGATCACC CGAGAAGGGG CGCAGAGGGT GTACATTGAA 
ATTAAGTTCA CTCTGAGGGA CTGCAACAGT CTTCCGGGCG TCATGGGGAC TTGCAAGGAG 
ACGTTTAACC TTTACTACTA TGAATCGGAC AACGACAAGG AGCGCTTCAT CAGAGAGAGC 
CAGTTCGGCA AGATCGACAC CATCGCAGCG GATGAGAGCT TTACACAGGT GGACATTGGG 
GACAGAATCA TGAAGCTCAA CACCGAGATC CGGGATGTAG GGCCCCTGAG CAAGAAGGGT 
TTTTACCTGG CTTTTCAGGA TGTGGGTGCT TGCATCGCCC TGGTGTCTGT TCGTGTGTTC 
TACAAGAAGT GTCCCCTCAC CGTTCGAAAT CTAGCCCAGT TCCCCGATAC CATCACTGGG 
GCTGATACCT CTTCCCTGGT GGAAGTTCGA GGCTCCTGTG TCAACAACTC AGAAGAGAAG 
GATGTGCCAA AAATGTACTG TGGGGCAGAT GGTGAATGGC TGGTACCCAT TGGCAACTGC 
CTATGCAATG CTGGGCACGA GGAGCAGAAT GGTGAATGCC AAGCTTGCAA AATTGGATAT 
TACAAAGCTC TCTCCACGGA CGCCACCTGT GCCAAGTGTC CACCGCACAG CTACTCTGTC 
TGGGAAGGAG CCACGTCCTG CACCTGTGAC CGAGGCTTTT TCAGAGCTGA CAACGATGCC 
GCGTCCATGC CCTGCACCCG CCCACCATCT GCTCCCCTCA ACTTGATTTC TAATGTCAAC 
GAGACGTCGG TGAACTTGGA ATGGAGCAGT CCTCAGAACA CAGGTGGCCG TCAGGACATT 
TCTTACAACG TGGTCTGCAA GAAATGTGGA GCTGGGGATC CCAGCAAGTG TCGACCCTGT 
GGAAGTGGAG TCCACTACAC GCCACAGCAG AATGGACTCA AGACGACCAG AGTCTCCATC 
ACTGACCTCC TAGCACACAC CAATTACACG TTTGAGATCT GGGCAGTGAA TGGCGTGTCT 
AAGTACAACC CTAGCCCAGA CCAGTCAGTG TCTGTCACAG TGACAACCAA CCAAGCAGCA 
CCATCATCCA TTGCTTTGGT CCAGGCTAAA GAAGTTACAA GATACAGTGT GGCTCTGGCT 
TGGCTGGAAC CAGATCGACC AAACGGAGTC ATCTTAGAAT ATGAAGTGAA ATATTATGAA 
AAGGATCAGA ATGAACGAAG CTATCGCATA GTTCGGACAG CTGCCAGGAA CACAGATATC 
AAAGGCCTGA ACCCTTTGAC TTCTTACGTC TTCCACGTGC GAGCCAGGAC CGCCGCTGGC 
TATGGAGACT TCAGCGAACC CTTGGAAGTC ACTACCAATA CAGTGCCTTC CCGAATCATT 
GGCGACGGGG CCAACTCTAC CGTCCTGCTG GTCTCCGTCT CTGGCAGTGT AGTACTCGTG 
GTCATTCTCA TTGCGGCATT TGTGATCAGC CGTAGACGGA GTAAGTACAG CCAAGCAAAG 
CAAGAAGCAG ATGAAGAGAA GCATTTGAAT CAAGGTGTTA GAACATACGT GGATCCCTTT 
ACATATGAAG ACCCCAACCA GGCAGTTCGA GAATTTGCCA AAGAAATCGA TGCCTCCTGC 
ATTAAAATCG AAAAGGTCAT TGGAGTTGGC GAATTTGGAG AAGTCTGCAG TGGGCGTCTC 
AAAGTGCCCG GCAAGAGAGA GATCTGTGTG GCCATCAAGA CTCTGAAAGC TGGTTATACT 
GACAAGCAGA GGAGAGACTT CCTGAGCGAG GCCAGCATCA TGGGACAGTT TGACCACCCA 
AACATAATCC ACCTGGAAGG CGTTGTCACC AAATGTAAAC CAGTAATGAT CATCACGGAG 
TACATGGAGA ACGGCTCCTT GGACGCTTTC CTCAGGAAGA ATGATGGCCG ATTTACAGTC 
ATTCAGCTGG TGGGCATGCT CCGAGGCATT GGCTCGGGGA TGAAGTACTT ATCTGATATG 
AGCTATGTGC ATCGAGACCT GGCTGCCAGG AACATTCTGG TAAACAGCAA CTTGGTCTGC 
AAGGTGTCTG ATTTCGGCAT GTCCAGGGTG CTTGAGGATG ACCCGGAAGC AGCCTATACT 
ACCAGGGGCG GCAAGATTCC CATCCGGTGG ACTGCACCAG AAGCAATTGC GTATCGTAAA 
TTTACCTCAG CCAGTGACGT CTGGAGCTAC GGAATCGTTA TGTGGGAAGT GATGTCATAT 
GGAGAGAGGC CGTACTGGGA TATGTCCAAT CAAGATGTGA TCAAAGCCAT CGAGGAAGGG 
TACCGGCTAC CCCCGCCAAT GGACTGCCCC ATTGCCCTCC ATCAGTTAAT GCTGGACTGT 
TGGCAGAAAG AGAGAAGCGA CAGGCCTAAA TTTGGGCAGA TCGTCAACAT GTTGGACAAA 
CTCATCCGCA ACCCCAACAG CCTGAAGAGG ACAGGGCCAG AGAGTTCCAG ACCAAACACA 
GCCTTGTTAG ATCCCAGCTC CCCTGAATTC TCCGCCGTAG TATCAGTGGG TGACTGGCTG 
CAGGCCATCA AAATGGACCG GTATAAGGAC AACTTCACAG CCGCCGGGTA CACGACACTA 
GAAGCTGTGG TTCACATGAG CCAGGAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Ephrin-A1-EphA4 signaling negatively regulates myelination in the central nervous system.
Glia(2018 Jan)
Harboe M,Torvund-Jensen J,Kjaer-Sorensen K,Laursen LS

EphrinA4 mimetic peptide targeted to EphA binding site impairs the formation of long-term fear memory in lateral amygdala.
Translational psychiatry4e450(2014 Sep)
Dines M,Lamprecht R

Nephric duct insertion requires EphA4/EphA7 signaling from the pericloacal mesenchyme.
Development (Cambridge, England)141(17)3420-30(2014 Sep)
Weiss AC,Airik R,Bohnenpoll T,Greulich F,Foik A,Trowe MO,Rudat C,Costantini F,Adams RH,Kispert A

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Epha4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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