Dclk3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Dclk3
Entrez Gene ID	316023
Full Name	doublecortin-like kinase 3
Synonyms	Dcamkl3,RGD1309232
General protein information	Preferred Names doublecortin-like kinase 3 Names serine/threonine-protein kinase DCLK3 doublecortin and CaM kinase-like 3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 8 Map Location: 8q32
Summary	This gene encodes a member of the protein kinase superfamily and the doublecortin family. Differently from the other two closely related family members (DCLK1 and DCLK2), the protein encoded by this gene contains only one N-terminal doublecortin domain and is unable to bind microtubules and to regulate microtubule polymerization. The protein contains a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmoduline-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. [provided by RefSeq, Sep 2010].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001191800.1	NP_001178729.1	serine/threonine-protein kinase DCLK3

Pathways from BioSystems

Homologies

Homo sapiens (human)	DCLK3	NP_208382.1
Pan troglodytes (chimpanzee)	DCLK3	XP_003309741.1
Canis lupus familiaris (dog)	DCLK3	XP_542700.3
Mus musculus (house mouse)	Dclk3	NP_766516.2
Bos taurus (cattle)	DCLK3	XP_003587668.2
Rattus norvegicus (Norway rat)	Dclk3	NP_001178729.1
Gallus gallus (chicken)	DCLK3	XP_001236017.3
Caenorhabditis elegans (roundworm)	F32D8.1	NP_505770.3
	DCLK3	XP_001088118.2

Gene Ontology
Bibliography

Related articles in PubMed

The doublecortin gene family and disorders of neuronal structure.
Dijkmans TF, van Hooijdonk LW, Fitzsimons CP, Vreugdenhil E
Central nervous system agents in medicinal chemistry10(1)32-46(2010 Mar)

Night/day changes in pineal expression of >600 genes: central role of adrenergic/cAMP signaling.
Bailey MJ, Coon SL, Carter DA, Humphries A, Kim JS, Shi Q, Gaildrat P, Morin F, Ganguly S, Hogenesch JB, Weller JL, Rath MF, M?ller M, Baler R, Sugden D, Rangel ZG, Munson PJ, Klein DC
The Journal of biological chemistry284(12)7606-22(2009 Mar)

The evolving doublecortin (DCX) superfamily.
Reiner O, Coquelle FM, Peter B, Levy T, Kaplan A, Sapir T, Orr I, Barkai N, Eichele G, Bergmann S
BMC genomics7188(2006 Jul)

Molecular identification and characterization of a family of kinases with homology to Ca2+/calmodulin-dependent protein kinases I/IV.
Ohmae S, Takemoto-Kimura S, Okamura M, Adachi-Morishima A, Nonaka M, Fuse T, Kida S, Tanji M, Furuyashiki T, Arakawa Y, Narumiya S, Okuno H, Bito H
The Journal of biological chemistry281(29)20427-39(2006 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Dclk3 is expressed in the pineal gland at levels >16-fold greater than the median expression level in other tissues; in addition, expression exhibits a >10-fold increase at night.
Title: Night/day changes in pineal expression of >600 genes: central role of adrenergic/cAMP signaling.

The following Dclk3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dclk3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa07689	NM_001191800.1 Latest version!	Rattus norvegicus doublecortin-like kinase 3 (Dclk3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Dclk3 ( NM_001191800.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001178729.1 Rattus norvegicus doublecortin-like kinase 3 (Dclk3), mRNA.

Price & Availability↑

CloneID	ORa07689
Clone ID Related Accession (Same CDS sequence)	NM_001191800.1
Accession Version	NM_001191800.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2424bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-28
Organism	Rattus norvegicus(Norway rat)
Product	serine/threonine-protein kinase DCLK3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07071517.1 and AABR07071518.1. On Jul 17, 2010 this sequence version replaced XM_236661.5. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMEA2689595 [ECO:0000348] ##Evidence-Data-END##

ATGCCAGCCG CGCCGGTCCT GCGCCCTCCG CCGCCACCGG CGACCCCTGC CCCGCCGGCA 
CCCAGCCGCC CTGCGCCTGC TATCTCGGGC CATCGGGGTC CGTGTGACCA TTCTCTAAAA 
TGCTTAAGCT CGAAGATCTC TGAGAGAAAG TTGCCAGGCT CCTGGCTGCC TTCGGGACGA 
GGACCTCTGG AGAAGCCAGT CCTGGGGCCA CGTGGTGCCG TCATGCCGAT GTTCAGCCCT 
CAGAGTAGCC TCCACTCAGT CCGCGCAGAG CACAGCCCAC TGAAGCCCAG GGTGGTTACG 
GTGGTGAAGC TGGGCGTGCA GCCCCTCCGC AAGGCCACCC TGCTCCTCAA CAGGCGGTCA 
GTGCAGACCT TTGAGCAGCT CCTGTCGGAC ATCTCTGAAG CCTTGGGCTT CCCGCGATGG 
AAGAATGACC GTGTGCGGAA GCTGTTCACC CTCAAGGGCA GGGAGGTCAA GAGTGTGTCT 
GACTTCTTCC GGGAGGGCGA TGCTTTCATA GCCATGGGCA AAGAGCCACT GACATTGAAG 
AGTATCCAGT TGGCTATGGA GGAACTGTAT CCTAAGAACC GCGCCCTTGC CCTGGCCCCT 
CATAGTAGAG TCCCCTCCCC AAGGCTAAGA AGCAGGCTTC CCAGCAAGCT TCTGAAAGGA 
AGTCACCGCT GTGGGGAGGC AGGAAGCTAT GGTGAGGTAA TGGGGAACAA GGCAGTCATT 
AGGCACCAGG GCAAGACTTC CACAGAGCTG GCCCCAGAAG ACAAGGCAAG GGCCCAGAAG 
AAGTGGGTAG GAGGGAAACA GGAATCAGAA AATGGTGGCC TGCCGTCACC TAGAGAAGCC 
ACTCAGGAGG AGACGCATGC AAGTGGGGAG AAGCACCTCG GGGTGGAGAT TGAAAAGACC 
TCGGGGGAGA TTGTCAGGTG TGAGAAGTGT AAGAGAGAAA CAGAGCTGCA GTTGGGCCTA 
CAGAGGGGGC AGTGCCCTCC GGGAACCAGT GAGCTGGACC TGGGGAGGGG CCAGAAGAGG 
GATTCCGAGA AGTTGGTCAG GACCAAGAGC TGCAGGAGGG CTTCTGAGGC AAAGTCTACA 
GATGGAGAGG AAGGGTGGAA GGGTGACAGC CACCGGGGCA GCCCCAGGGA TCCCCCTCAG 
GAACTGAGGA GGCCCAACAA CAACTCAGAC AAGAAAGAGA GCAGAGGCTC AGAAGCTCAG 
GAAAGTCACC CTCAGGGCGT GGCCAAGGCC CAGAAGGACC TCATGGAAGG TCTGCCAGCT 
GTAGAGGAGG GGGCGGTGGA CGCGAGGAGA GATTCCAGGC ACACATGCAG GATTAAGCAT 
GCTGCCTGGC TCCGGAGAGA GCAGCAGGCT GAACCCCCAC AGCTCCCCAG AACCCGAGGG 
GAGGAGAAGG AAGCAGAGCA TGAGAAGAAG TCAGGTGGTC TGGGAGGGAG GAGGATGCTA 
GAAAAGGAGT CTAAGACGAA GCCGGAAGAG AACCGGCCGG AACGACCCAG TGGCCGGAAG 
CTGAGGCCCA CGGGCATCAT CTCAGCGGAT GTGGAGAAGC ACTATGACAT AGGTCGGGTC 
ATTGGGGATG GGAATTTTGC CATCGTGAAG GAATGCAAGC ACCGAGAGAC CAGGCAGGCT 
TACGCCATGA AGATTATTGA CAAATCCCAG CTGAAGGGTA AGGAGGACAT TGTGGACAGT 
GAGATTTTAA TTATCCAGAG TCTCTCTCAC CCCAACATAG TGAAACTGCA TGAGGTCTAC 
GAAACAGAGG CAGAGATCTA CCTGATCATG GAGTACGTGC AGGGAGGGGA CCTTTTCGAT 
GCCATCATCG AAAGTGTGAA GTTTCCAGAG CCTGACGCTG CAGTTATGAT CACAGACTTG 
TGTAAGGCCC TCGTCCACAT GCATGACAAG AAGATCGTCC ACCGGGACCT GAAGCCGGAA 
AACCTCCTGG TTCAGCGAAA TGAAGACAAG TCTACCACCT TGAAGCTGGC TGACTTTGGC 
CTGGCCAAAC ATGTGGTGAG GCCTATATTT ACTGTGTGTG GGACGCCAAC ATATGTAGCT 
CCTGAGATTC TTTCTGAGAA AGGTTACGGC CTGGAGGTGG ACATGTGGGC CGCAGGTGTG 
ATCCTATACA TCCTCTTGTG TGGCTTCCCT CCTTTCCGAA GTCCTGAGAG GGACCAAGAC 
GAGCTCTTCA ACATCATCCA GCTGGGCCAG TTTGAGTTCC TCTCTCCTTA CTGGGACAAC 
ATTTCTGATG CTGCCAAAGA TCTGGTGAGA AATTTGCTGG TAGTGGACCC CAAGAAGCGG 
TACACGGCCC ACCAGGTCCT ACATCATCCC TGGATTGGGA TGGTGGGGCA CCCCAGCACA 
GTGAACCCAC AGAAGGAGGA GTCCCCCAGC AGCGAGGGTC GCTTCCAGAG CCAGCACAAG 
AAGGTTGCAG AGCACGTGTC GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001178729.1
CDS	1..2424
Translation	MPAAPVLRPPPPPATPAPPAPSRPAPAISGHRGPCDHSLKCLSSKISERKLPGSWLPSGRGPLEKPVLGPRGAVMPMFSPQSSLHSVRAEHSPLKPRVVTVVKLGVQPLRKATLLLNRRSVQTFEQLLSDISEALGFPRWKNDRVRKLFTLKGREVKSVSDFFREGDAFIAMGKEPLTLKSIQLAMEELYPKNRALALAPHSRVPSPRLRSRLPSKLLKGSHRCGEAGSYGEVMGNKAVIRHQGKTSTELAPEDKARAQKKWVGGKQESENGGLPSPREATQEETHASGEKHLGVEIEKTSGEIVRCEKCKRETELQLGLQRGQCPPGTSELDLGRGQKRDSEKLVRTKSCRRASEAKSTDGEEGWKGDSHRGSPRDPPQELRRPNNNSDKKESRGSEAQESHPQGVAKAQKDLMEGLPAVEEGAVDARRDSRHTCRIKHAAWLRREQQAEPPQLPRTRGEEKEAEHEKKSGGLGGRRMLEKESKTKPEENRPERPSGRKLRPTGIISADVEKHYDIGRVIGDGNFAIVKECKHRETRQAYAMKIIDKSQLKGKEDIVDSEILIIQSLSHPNIVKLHEVYETEAEIYLIMEYVQGGDLFDAIIESVKFPEPDAAVMITDLCKALVHMHDKKIVHRDLKPENLLVQRNEDKSTTLKLADFGLAKHVVRPIFTVCGTPTYVAPEILSEKGYGLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGQFEFLSPYWDNISDAAKDLVRNLLVVDPKKRYTAHQVLHHPWIGMVGHPSTVNPQKEESPSSEGRFQSQHKKVAEHVS

Target ORF information:

RefSeq Version	NM_001191800.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus doublecortin-like kinase 3 (Dclk3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001191800.1

ORF Insert Sequence:

ATGCCAGCCG CGCCGGTCCT GCGCCCTCCG CCGCCACCGG CGACCCCTGC CCCGCCGGCA 
CCCAGCCGCC CTGCGCCTGC TATCTCGGGC CATCGGGGTC CGTGTGACCA TTCTCTAAAA 
TGCTTAAGCT CGAAGATCTC TGAGAGAAAG TTGCCAGGCT CCTGGCTGCC TTCGGGACGA 
GGACCTCTGG AGAAGCCAGT CCTGGGGCCA CGTGGTGCCG TCATGCCGAT GTTCAGCCCT 
CAGAGTAGCC TCCACTCAGT CCGCGCAGAG CACAGCCCAC TGAAGCCCAG GGTGGTTACG 
GTGGTGAAGC TGGGCGTGCA GCCCCTCCGC AAGGCCACCC TGCTCCTCAA CAGGCGGTCA 
GTGCAGACCT TTGAGCAGCT CCTGTCGGAC ATCTCTGAAG CCTTGGGCTT CCCGCGATGG 
AAGAATGACC GTGTGCGGAA GCTGTTCACC CTCAAGGGCA GGGAGGTCAA GAGTGTGTCT 
GACTTCTTCC GGGAGGGCGA TGCTTTCATA GCCATGGGCA AAGAGCCACT GACATTGAAG 
AGTATCCAGT TGGCTATGGA GGAACTGTAT CCTAAGAACC GCGCCCTTGC CCTGGCCCCT 
CATAGTAGAG TCCCCTCCCC AAGGCTAAGA AGCAGGCTTC CCAGCAAGCT TCTGAAAGGA 
AGTCACCGCT GTGGGGAGGC AGGAAGCTAT GGTGAGGTAA TGGGGAACAA GGCAGTCATT 
AGGCACCAGG GCAAGACTTC CACAGAGCTG GCCCCAGAAG ACAAGGCAAG GGCCCAGAAG 
AAGTGGGTAG GAGGGAAACA GGAATCAGAA AATGGTGGCC TGCCGTCACC TAGAGAAGCC 
ACTCAGGAGG AGACGCATGC AAGTGGGGAG AAGCACCTCG GGGTGGAGAT TGAAAAGACC 
TCGGGGGAGA TTGTCAGGTG TGAGAAGTGT AAGAGAGAAA CAGAGCTGCA GTTGGGCCTA 
CAGAGGGGGC AGTGCCCTCC GGGAACCAGT GAGCTGGACC TGGGGAGGGG CCAGAAGAGG 
GATTCCGAGA AGTTGGTCAG GACCAAGAGC TGCAGGAGGG CTTCTGAGGC AAAGTCTACA 
GATGGAGAGG AAGGGTGGAA GGGTGACAGC CACCGGGGCA GCCCCAGGGA TCCCCCTCAG 
GAACTGAGGA GGCCCAACAA CAACTCAGAC AAGAAAGAGA GCAGAGGCTC AGAAGCTCAG 
GAAAGTCACC CTCAGGGCGT GGCCAAGGCC CAGAAGGACC TCATGGAAGG TCTGCCAGCT 
GTAGAGGAGG GGGCGGTGGA CGCGAGGAGA GATTCCAGGC ACACATGCAG GATTAAGCAT 
GCTGCCTGGC TCCGGAGAGA GCAGCAGGCT GAACCCCCAC AGCTCCCCAG AACCCGAGGG 
GAGGAGAAGG AAGCAGAGCA TGAGAAGAAG TCAGGTGGTC TGGGAGGGAG GAGGATGCTA 
GAAAAGGAGT CTAAGACGAA GCCGGAAGAG AACCGGCCGG AACGACCCAG TGGCCGGAAG 
CTGAGGCCCA CGGGCATCAT CTCAGCGGAT GTGGAGAAGC ACTATGACAT AGGTCGGGTC 
ATTGGGGATG GGAATTTTGC CATCGTGAAG GAATGCAAGC ACCGAGAGAC CAGGCAGGCT 
TACGCCATGA AGATTATTGA CAAATCCCAG CTGAAGGGTA AGGAGGACAT TGTGGACAGT 
GAGATTTTAA TTATCCAGAG TCTCTCTCAC CCCAACATAG TGAAACTGCA TGAGGTCTAC 
GAAACAGAGG CAGAGATCTA CCTGATCATG GAGTACGTGC AGGGAGGGGA CCTTTTCGAT 
GCCATCATCG AAAGTGTGAA GTTTCCAGAG CCTGACGCTG CAGTTATGAT CACAGACTTG 
TGTAAGGCCC TCGTCCACAT GCATGACAAG AAGATCGTCC ACCGGGACCT GAAGCCGGAA 
AACCTCCTGG TTCAGCGAAA TGAAGACAAG TCTACCACCT TGAAGCTGGC TGACTTTGGC 
CTGGCCAAAC ATGTGGTGAG GCCTATATTT ACTGTGTGTG GGACGCCAAC ATATGTAGCT 
CCTGAGATTC TTTCTGAGAA AGGTTACGGC CTGGAGGTGG ACATGTGGGC CGCAGGTGTG 
ATCCTATACA TCCTCTTGTG TGGCTTCCCT CCTTTCCGAA GTCCTGAGAG GGACCAAGAC 
GAGCTCTTCA ACATCATCCA GCTGGGCCAG TTTGAGTTCC TCTCTCCTTA CTGGGACAAC 
ATTTCTGATG CTGCCAAAGA TCTGGTGAGA AATTTGCTGG TAGTGGACCC CAAGAAGCGG 
TACACGGCCC ACCAGGTCCT ACATCATCCC TGGATTGGGA TGGTGGGGCA CCCCAGCACA 
GTGAACCCAC AGAAGGAGGA GTCCCCCAGC AGCGAGGGTC GCTTCCAGAG CCAGCACAAG 
AAGGTTGCAG AGCACGTGTC GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The doublecortin gene family and disorders of neuronal structure.
Central nervous system agents in medicinal chemistry10(1)32-46(2010 Mar)
Dijkmans TF,van Hooijdonk LW,Fitzsimons CP,Vreugdenhil E

Night/day changes in pineal expression of >600 genes: central role of adrenergic/cAMP signaling.
The Journal of biological chemistry284(12)7606-22(2009 Mar)
Bailey MJ,Coon SL,Carter DA,Humphries A,Kim JS,Shi Q,Gaildrat P,Morin F,Ganguly S,Hogenesch JB,Weller JL,Rath MF,M?ller M,Baler R,Sugden D,Rangel ZG,Munson PJ,Klein DC

The evolving doublecortin (DCX) superfamily.
BMC genomics7188(2006 Jul)
Reiner O,Coquelle FM,Peter B,Levy T,Kaplan A,Sapir T,Orr I,Barkai N,Eichele G,Bergmann S

Molecular identification and characterization of a family of kinases with homology to Ca2+/calmodulin-dependent protein kinases I/IV.
The Journal of biological chemistry281(29)20427-39(2006 Jul)
Ohmae S,Takemoto-Kimura S,Okamura M,Adachi-Morishima A,Nonaka M,Fuse T,Kida S,Tanji M,Furuyashiki T,Arakawa Y,Narumiya S,Okuno H,Bito H

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Dclk3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報