Fam83b cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fam83b
Entrez Gene ID	315829
Full Name	family with sequence similarity 83, member B
Synonyms	RGD1311988
General protein information	Preferred Names family with sequence similarity 83, member B Names protein FAM83B
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 8 Map Location: 8q24

mRNA and Protein(s)

mRNA	Protein	Name
NM_001108169.1	NP_001101639.1	protein FAM83B

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	fam83b	XP_005170836.1
Canis lupus familiaris (dog)	FAM83B	XP_538971.2
Mus musculus (house mouse)	Fam83b	NP_001038983.1
Gallus gallus (chicken)	FAM83B	XP_426203.2
Homo sapiens (human)	FAM83B	NP_001010872.1
Bos taurus (cattle)	FAM83B	NP_001192724.1
Rattus norvegicus (Norway rat)	Fam83b	NP_001101639.1
Pan troglodytes (chimpanzee)	FAM83B	XP_518551.1
Xenopus tropicalis (tropical clawed frog)	fam83b	XP_002934897.1
	FAM83B	XP_001109565.1

Gene Ontology
Bibliography

Related articles in PubMed

Hyperactivation of EGFR and downstream effector phospholipase D1 by oncogenic FAM83B.
Cipriano R, Bryson BL, Miskimen KL, Bartel CA, Hernandez-Sanchez W, Bruntz RC, Scott SA, Lindsley CW, Brown HA, Jackson MW
Oncogene33(25)3298-306(2014 Jun)

FAM83B-mediated activation of PI3K/AKT and MAPK signaling cooperates to promote epithelial cell transformation and resistance to targeted therapies.
Cipriano R, Miskimen KL, Bryson BL, Foy CR, Bartel CA, Jackson MW
Oncotarget4(5)729-38(2013 May)

FAM83B mediates EGFR- and RAS-driven oncogenic transformation.
Cipriano R, Graham J, Miskimen KL, Bryson BL, Bruntz RC, Scott SA, Brown HA, Stark GR, Jackson MW
The Journal of clinical investigation122(9)3197-210(2012 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Fam83b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fam83b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06807	NM_001108169.1 Latest version!	Rattus norvegicus family with sequence similarity 83, member B (Fam83b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fam83b ( NM_001108169.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101639.1 Rattus norvegicus family with sequence similarity 83, member B (Fam83b), mRNA.

Price & Availability↑

CloneID	ORa06807
Clone ID Related Accession (Same CDS sequence)	NM_001108169.1
Accession Version	NM_001108169.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3027bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Rattus norvegicus(Norway rat)
Product	protein FAM83B
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473954.2. On or before Oct 4, 2007 this sequence version replaced XM_236420.4, XM_001058463.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2689599, SAMEA2689602 [ECO:0000348] ##Evidence-Data-END##

ATGGAGACTT CATCAATGCT TTCCTCACTA AATGATGAGT GCAGGTCTGA CAACTATGTC 
GAGCCGCACT ACAAGGAGTG GTACCGTGTG GCAGTTGATA CTCTAATTGA ACATGGGCTA 
GAAGCCTACC AAGAGTTCCT TGTCAAGGAG CGAGTCTCAG ACTTCCTGGC TGAGGAAGAA 
ATTAATTATA TTTTGAAAAA TGTCCAGAAG ATTGCACAAA ATACAGAACA TGGCTCTGAT 
AGTTCCTGTG ATGACGGCTC GTCTTCAGGG ACTTACTGGC CCATGCAGTC GGACGTGGAG 
GCTCCAAATC TTGATTTGGG ATGGCCGTGT GTGATGCCCG GACTCTTAGG GAGCACCCAT 
ATAGACCTCC TCTTTCATCC ACCCCGGGCA CATCTACTTA CAATAAAGGA AACTGTTCGG 
AAGATGATCA AAGACGCAAG AAAGGTGGTT GCTATAGTGA TGGATGTTTT TACTGATGTG 
GATATTTTCA AAGAAATAGT AGAGGCATCC ACTCGAGGAA TATCCGTATA CATTTTACTT 
GATGAGTCCA ATTTTAATCA TTTTCTAACA ATGACTGAAA AACAGGGTTG TCAAATTCAG 
CGTCTCAGGA ACATTCGTGT ACGGACAGTA AAAGGCCAAG ATTATCTTTC AAAAACAGGA 
GCAAAATTCC ATGGAAAAAT GGAACAGAAA TTTTTGTTAG TTGACTGCCA GAAAGTGATG 
TATGGTTCTT ACAGTTACAT GTGGTCATTT GAAAAAGCTC ATCTCAGCAT GGTTCAGATA 
ATCACAGGAC ACCTTGTAGA GTTATTTGAT GAAGAATTTC GAACACTCTA TGCCAGGTCC 
AGTGTCCCAA GTTGTTTTGC TCAAGAAGAA TCAACGAGGG TGAAGCCGGG CAAAGCCTTA 
TGGGAGAATG GCATTTACCA GCGATCCATT TCTTCATTAG CTTCTGTTTC CAGCCAGAGA 
AACCTTTTTG GCAGACAAGA CCAAATTCAT AAACTAGATT CTAGTTACTT CAAAGGCAGA 
GGGATATATC CCCTAAATGA ACAGGACAAA CACGGCATGA GAAACCATGG CTACAAGCCT 
CATTTTGTTC CAAACTTCAA TGGTCCGAGT GCAATCCGTC ACTTCCAACC CAGTCAGATC 
AATGAAAACT GGAAGAGGCA TAGTTATGCT GGGGAACAAT CGGAAACAAC CCCGTACCTG 
CTGCTCAACA GAGCTATGAA TCGGACCAAT AATGCCCCTG GACGCTGGAG AAGGCCTTCA 
GATAGTCTCA GTGTGGCATC CTCCTTACGG GGAGGACAGG GAAGCCAGCA AAACATACCT 
GCTCAGAGTT TTGCTGATAG GCTCGCCCAG AGAAAAACAA CAAATCTTGC AGAGAGGAAT 
TCAAATGTAC GCAGGTCATT TAACGGGACA GATAATCATA TCCGCTTTAT ACAACAACGG 
ATGCCAACTC TGGAGAATAC CACGAAGTCT TTCCTGCGGA GCTGGAGAAT TGAATCGTAC 
TTAAACGATA ATTCAGAAGC CCCACCTGAT TCAAATGGCT CCACCCTGGG TGACAGATTT 
GAAGGCTACG ACAACCCTGA GACCGTGAAA GCCAATGCGG TCTATACTCA TTCAAGGCTC 
CGCTCCTCCT TTGTGTTTAA ACCAACTTTA CCGGAACAAA AAGAAGTCAA TAGCTGTACA 
ACTGGCTCCT CAAATTCCAC CATCATCGGT TCTCAAGGAA GGGATACACC CAAGGAGCTC 
CCAGAGAGCT CCACAAATGC TCCTCCACCC CTGACAGAAA AGCCCTTGCC GGAATCAATC 
CCCAAGCTCC CAACACAGTC AGAGGAACCA AAAACGCACA GCTTGCGGGT TCCCGAAAAG 
CAACCGGAAG TCTTAAACCA AAGAACCAAC GGCCGAGCGG AACTAAACAA CTGTATTTAT 
ACAAAACTGT GCGTCAATAA GCCAATGGAG AACGCAAAAA ATCAGCCAAG CGACAATCTG 
CTCAAAAGGC GGAGTTTCCC GTCCTTCGAC CACTCAAAAG TCAACTTGGA TCACGGAAAT 
AGCAAGAATT ATGTTTATAG TACCCTTACC AGAAATCGCA TTCGGCAACC AGAAAAACCC 
AAGGAGGATG TGCTGAAGAG TTCTAAGAGC TTGCACAATG TGACCCACAG CACGGATGAA 
GACGACGACG AGGTTACTAA GAGAGACCCT CCAAGTGCCT CTGCCAAGTC TATTTCCATC 
GCTGCTTTGC TGGACGTGAA TAAGGAAGAA CCCAACAAAG AACTCAATTC TAAAAAGGAA 
GGCAAAGCCT CCCCGAGTTT TCTGAAAAAG GGGTCTCAGA AATTAAGGTC CTTACTTAGT 
CTCACCCCAG AGAAGAGAGA GAACCTAGCT AAAAACAAGG CGCCGGCGTT TTACAGAATG 
TGTAGTAGCT CCGACACTTT GGTTTCTGAG GGTGAAGAGA ATCAAAAGCC CAAAAAATCC 
GAGCCCAAAG GTGACGCATC TCCTAGAAGA AAGCGTTCCT CTTTGTCGAA TTCTCAAGGC 
AGCATCCACA AGAGCAAGGA GGACATAGCA GTTAGCACAT CTCCGGGAAT AAGTTCCCAA 
GTAGAGGAAA CTAGAATAGC CCCCTCTCCA AGGCCCGCTG AGAGGAGACT TTCAGAGAGA 
GCTGGAGACG CCTCTGCCCC AAGATTTAAT ACCGAACAGA TCCAATACCG TGATTCCAAG 
GAGATCAACG CAGTCATGAC CCCTGCCAGA CGGCCAACCT CTTCTCCGGT GCTAAAACCC 
AGTGAGCTTC TGAGATCCCA TTCAACCAAC CAGCGCGTTT ACAGTCGATT CGAGCCGTTT 
TGTAAGATCG AGAGCTCGAT TCAGCCAGCG AGCAGCGTTA CACATGTCAA CCGCCCGGAA 
GTCAAATCCA CAACCATGGG CAGCTACGGC AGGTCCAGCC CGATGCTGAA TTATAAGACT 
GGTGCTTATC AATCCTACTC CCCAAATGAG AACAAGTTCC GGGGATTTAT GCAAAAGTTT 
GGGAACTTCA TACACAAAAA CAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101639.1
CDS	116..3142
Translation	METSSMLSSLNDECRSDNYVEPHYKEWYRVAVDTLIEHGLEAYQEFLVKERVSDFLAEEEINYILKNVQKIAQNTEHGSDSSCDDGSSSGTYWPMQSDVEAPNLDLGWPCVMPGLLGSTHIDLLFHPPRAHLLTIKETVRKMIKDARKVVAIVMDVFTDVDIFKEIVEASTRGISVYILLDESNFNHFLTMTEKQGCQIQRLRNIRVRTVKGQDYLSKTGAKFHGKMEQKFLLVDCQKVMYGSYSYMWSFEKAHLSMVQIITGHLVELFDEEFRTLYARSSVPSCFAQEESTRVKPGKALWENGIYQRSISSLASVSSQRNLFGRQDQIHKLDSSYFKGRGIYPLNEQDKHGMRNHGYKPHFVPNFNGPSAIRHFQPSQINENWKRHSYAGEQSETTPYLLLNRAMNRTNNAPGRWRRPSDSLSVASSLRGGQGSQQNIPAQSFADRLAQRKTTNLAERNSNVRRSFNGTDNHIRFIQQRMPTLENTTKSFLRSWRIESYLNDNSEAPPDSNGSTLGDRFEGYDNPETVKANAVYTHSRLRSSFVFKPTLPEQKEVNSCTTGSSNSTIIGSQGRDTPKELPESSTNAPPPLTEKPLPESIPKLPTQSEEPKTHSLRVPEKQPEVLNQRTNGRAELNNCIYTKLCVNKPMENAKNQPSDNLLKRRSFPSFDHSKVNLDHGNSKNYVYSTLTRNRIRQPEKPKEDVLKSSKSLHNVTHSTDEDDDEVTKRDPPSASAKSISIAALLDVNKEEPNKELNSKKEGKASPSFLKKGSQKLRSLLSLTPEKRENLAKNKAPAFYRMCSSSDTLVSEGEENQKPKKSEPKGDASPRRKRSSLSNSQGSIHKSKEDIAVSTSPGISSQVEETRIAPSPRPAERRLSERAGDASAPRFNTEQIQYRDSKEINAVMTPARRPTSSPVLKPSELLRSHSTNQRVYSRFEPFCKIESSIQPASSVTHVNRPEVKSTTMGSYGRSSPMLNYKTGAYQSYSPNENKFRGFMQKFGNFIHKNK

Target ORF information:

RefSeq Version	NM_001108169.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus family with sequence similarity 83, member B (Fam83b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108169.1

ORF Insert Sequence:

ATGGAGACTT CATCAATGCT TTCCTCACTA AATGATGAGT GCAGGTCTGA CAACTATGTC 
GAGCCGCACT ACAAGGAGTG GTACCGTGTG GCAGTTGATA CTCTAATTGA ACATGGGCTA 
GAAGCCTACC AAGAGTTCCT TGTCAAGGAG CGAGTCTCAG ACTTCCTGGC TGAGGAAGAA 
ATTAATTATA TTTTGAAAAA TGTCCAGAAG ATTGCACAAA ATACAGAACA TGGCTCTGAT 
AGTTCCTGTG ATGACGGCTC GTCTTCAGGG ACTTACTGGC CCATGCAGTC GGACGTGGAG 
GCTCCAAATC TTGATTTGGG ATGGCCGTGT GTGATGCCCG GACTCTTAGG GAGCACCCAT 
ATAGACCTCC TCTTTCATCC ACCCCGGGCA CATCTACTTA CAATAAAGGA AACTGTTCGG 
AAGATGATCA AAGACGCAAG AAAGGTGGTT GCTATAGTGA TGGATGTTTT TACTGATGTG 
GATATTTTCA AAGAAATAGT AGAGGCATCC ACTCGAGGAA TATCCGTATA CATTTTACTT 
GATGAGTCCA ATTTTAATCA TTTTCTAACA ATGACTGAAA AACAGGGTTG TCAAATTCAG 
CGTCTCAGGA ACATTCGTGT ACGGACAGTA AAAGGCCAAG ATTATCTTTC AAAAACAGGA 
GCAAAATTCC ATGGAAAAAT GGAACAGAAA TTTTTGTTAG TTGACTGCCA GAAAGTGATG 
TATGGTTCTT ACAGTTACAT GTGGTCATTT GAAAAAGCTC ATCTCAGCAT GGTTCAGATA 
ATCACAGGAC ACCTTGTAGA GTTATTTGAT GAAGAATTTC GAACACTCTA TGCCAGGTCC 
AGTGTCCCAA GTTGTTTTGC TCAAGAAGAA TCAACGAGGG TGAAGCCGGG CAAAGCCTTA 
TGGGAGAATG GCATTTACCA GCGATCCATT TCTTCATTAG CTTCTGTTTC CAGCCAGAGA 
AACCTTTTTG GCAGACAAGA CCAAATTCAT AAACTAGATT CTAGTTACTT CAAAGGCAGA 
GGGATATATC CCCTAAATGA ACAGGACAAA CACGGCATGA GAAACCATGG CTACAAGCCT 
CATTTTGTTC CAAACTTCAA TGGTCCGAGT GCAATCCGTC ACTTCCAACC CAGTCAGATC 
AATGAAAACT GGAAGAGGCA TAGTTATGCT GGGGAACAAT CGGAAACAAC CCCGTACCTG 
CTGCTCAACA GAGCTATGAA TCGGACCAAT AATGCCCCTG GACGCTGGAG AAGGCCTTCA 
GATAGTCTCA GTGTGGCATC CTCCTTACGG GGAGGACAGG GAAGCCAGCA AAACATACCT 
GCTCAGAGTT TTGCTGATAG GCTCGCCCAG AGAAAAACAA CAAATCTTGC AGAGAGGAAT 
TCAAATGTAC GCAGGTCATT TAACGGGACA GATAATCATA TCCGCTTTAT ACAACAACGG 
ATGCCAACTC TGGAGAATAC CACGAAGTCT TTCCTGCGGA GCTGGAGAAT TGAATCGTAC 
TTAAACGATA ATTCAGAAGC CCCACCTGAT TCAAATGGCT CCACCCTGGG TGACAGATTT 
GAAGGCTACG ACAACCCTGA GACCGTGAAA GCCAATGCGG TCTATACTCA TTCAAGGCTC 
CGCTCCTCCT TTGTGTTTAA ACCAACTTTA CCGGAACAAA AAGAAGTCAA TAGCTGTACA 
ACTGGCTCCT CAAATTCCAC CATCATCGGT TCTCAAGGAA GGGATACACC CAAGGAGCTC 
CCAGAGAGCT CCACAAATGC TCCTCCACCC CTGACAGAAA AGCCCTTGCC GGAATCAATC 
CCCAAGCTCC CAACACAGTC AGAGGAACCA AAAACGCACA GCTTGCGGGT TCCCGAAAAG 
CAACCGGAAG TCTTAAACCA AAGAACCAAC GGCCGAGCGG AACTAAACAA CTGTATTTAT 
ACAAAACTGT GCGTCAATAA GCCAATGGAG AACGCAAAAA ATCAGCCAAG CGACAATCTG 
CTCAAAAGGC GGAGTTTCCC GTCCTTCGAC CACTCAAAAG TCAACTTGGA TCACGGAAAT 
AGCAAGAATT ATGTTTATAG TACCCTTACC AGAAATCGCA TTCGGCAACC AGAAAAACCC 
AAGGAGGATG TGCTGAAGAG TTCTAAGAGC TTGCACAATG TGACCCACAG CACGGATGAA 
GACGACGACG AGGTTACTAA GAGAGACCCT CCAAGTGCCT CTGCCAAGTC TATTTCCATC 
GCTGCTTTGC TGGACGTGAA TAAGGAAGAA CCCAACAAAG AACTCAATTC TAAAAAGGAA 
GGCAAAGCCT CCCCGAGTTT TCTGAAAAAG GGGTCTCAGA AATTAAGGTC CTTACTTAGT 
CTCACCCCAG AGAAGAGAGA GAACCTAGCT AAAAACAAGG CGCCGGCGTT TTACAGAATG 
TGTAGTAGCT CCGACACTTT GGTTTCTGAG GGTGAAGAGA ATCAAAAGCC CAAAAAATCC 
GAGCCCAAAG GTGACGCATC TCCTAGAAGA AAGCGTTCCT CTTTGTCGAA TTCTCAAGGC 
AGCATCCACA AGAGCAAGGA GGACATAGCA GTTAGCACAT CTCCGGGAAT AAGTTCCCAA 
GTAGAGGAAA CTAGAATAGC CCCCTCTCCA AGGCCCGCTG AGAGGAGACT TTCAGAGAGA 
GCTGGAGACG CCTCTGCCCC AAGATTTAAT ACCGAACAGA TCCAATACCG TGATTCCAAG 
GAGATCAACG CAGTCATGAC CCCTGCCAGA CGGCCAACCT CTTCTCCGGT GCTAAAACCC 
AGTGAGCTTC TGAGATCCCA TTCAACCAAC CAGCGCGTTT ACAGTCGATT CGAGCCGTTT 
TGTAAGATCG AGAGCTCGAT TCAGCCAGCG AGCAGCGTTA CACATGTCAA CCGCCCGGAA 
GTCAAATCCA CAACCATGGG CAGCTACGGC AGGTCCAGCC CGATGCTGAA TTATAAGACT 
GGTGCTTATC AATCCTACTC CCCAAATGAG AACAAGTTCC GGGGATTTAT GCAAAAGTTT 
GGGAACTTCA TACACAAAAA CAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Hyperactivation of EGFR and downstream effector phospholipase D1 by oncogenic FAM83B.
Oncogene33(25)3298-306(2014 Jun)
Cipriano R,Bryson BL,Miskimen KL,Bartel CA,Hernandez-Sanchez W,Bruntz RC,Scott SA,Lindsley CW,Brown HA,Jackson MW

FAM83B-mediated activation of PI3K/AKT and MAPK signaling cooperates to promote epithelial cell transformation and resistance to targeted therapies.
Oncotarget4(5)729-38(2013 May)
Cipriano R,Miskimen KL,Bryson BL,Foy CR,Bartel CA,Jackson MW

FAM83B mediates EGFR- and RAS-driven oncogenic transformation.
The Journal of clinical investigation122(9)3197-210(2012 Sep)
Cipriano R,Graham J,Miskimen KL,Bryson BL,Bruntz RC,Scott SA,Brown HA,Stark GR,Jackson MW

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Fam83b cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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