The following Tdp1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tdp1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa08088 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001031657.1 | |
| Accession Version | NM_001031657.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1830bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-02-16 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | tyrosyl-DNA phosphodiesterase 1 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC098739.1. On Aug 12, 2005 this sequence version replaced XM_234379.3. ##Evidence-Data-START## Transcript exon combination :: BC098739.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGTCCCAGG AAAGCAGCTA CGGAAAGTGG ACAATATCCA GTAGTGACGA CAGCGAGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001026827.1 |
| CDS | 17..1846 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001031657.1 |
1 | ATGTCCCAGG AAAGCAGCTA CGGAAAGTGG ACAATATCCA GTAGTGACGA CAGCGAGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa29532 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006240432.3 | |
| Accession Version | XM_006240432.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1878bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | tyrosyl-DNA phosphodiesterase 1 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005105.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006240432.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGACGAAGA TCGGCATAGT CTGTGCAAGG ATGGCACACA GAAGTACAAT GTCCCAGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006240494.1 |
| CDS | 307..2184 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006240432.3 |
1 | ATGACGAAGA TCGGCATAGT CTGTGCAAGG ATGGCACACA GAAGTACAAT GTCCCAGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Biochemical characterization of human tyrosyl-DNA phosphodiesterase 2 (TDP2/TTRAP): a Mg(2+)/Mn(2+)-dependent phosphodiesterase specific for the repair of topoisomerase cleavage complexes. |
DNA ligase III is critical for mtDNA integrity but not Xrcc1-mediated nuclear DNA repair. |
TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivo. |
Spinocerebellar ataxia with axonal neuropathy: consequence of a Tdp1 recessive neomorphic mutation? |
TDP1 facilitates repair of ionizing radiation-induced DNA single-strand breaks. |
