gRNAs
The following Sel1l gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sel1l cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa04081 | |
| Clone ID Related Accession (Same CDS sequence) | NM_177933.3 | |
| Accession Version | NM_177933.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2382bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-08 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | protein sel-1 homolog 1 precursor | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07065212.1 and AABR07065211.1. On Nov 30, 2016 this sequence version replaced NM_177933.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## | |
1 | ATGCAGGTCC GCGTCAGACT GTTGTTGCTG CTCTGCGCGG TGCTCCTGGG CTCGGCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_808794.2 |
| CDS | 93..2474 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_177933.3 |
1 | ATGCAGGTCC GCGTCAGACT GTTGTTGCTG CTCTGCGCGG TGCTCCTGGG CTCGGCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa61623 | |
| Clone ID Related Accession (Same CDS sequence) | XM_017594162.1 | |
| Accession Version | XM_017594162.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2232bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | protein sel-1 homolog 1 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005105.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGCAGGTCC GCGTCAGACT GTTGTTGCTG CTCTGCGCGG TGCTCCTGGG CTCGGCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_017449651.1 |
| CDS | 139..2370 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_017594162.1 |
1 | ATGCAGGTCC GCGTCAGACT GTTGTTGCTG CTCTGCGCGG TGCTCCTGGG CTCGGCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa61624 | |
| Clone ID Related Accession (Same CDS sequence) | XM_017594163.1 | |
| Accession Version | XM_017594163.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2214bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | protein sel-1 homolog 1 isoform X2 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005105.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGCAGGTCC GCGTCAGACT GTTGTTGCTG CTCTGCGCGG TGCTCCTGGG CTCGGCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_017449652.1 |
| CDS | 139..2352 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_017594163.1 |
1 | ATGCAGGTCC GCGTCAGACT GTTGTTGCTG CTCTGCGCGG TGCTCCTGGG CTCGGCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Association of the SEL1L protein transmembrane domain with HRD1 ubiquitin ligase regulates ERAD-L. |
Identification of ERAD components essential for dislocation of the null Hong Kong variant of ?-1-antitrypsin (NHK). |
The ER-associated degradation adaptor protein Sel1L regulates LPL secretion and lipid metabolism. |
SEL1L protein critically determines the stability of the HRD1-SEL1L endoplasmic reticulum-associated degradation (ERAD) complex to optimize the degradation kinetics of ERAD substrates. |
Deficiency of suppressor enhancer Lin12 1 like (SEL1L) in mice leads to systemic endoplasmic reticulum stress and embryonic lethality. |
