Cc2d1b cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Cc2d1b
Entrez Gene ID	313478
Full Name	coiled-coil and C2 domain containing 1B
Synonyms	RGD1306630
General protein information	Preferred Names coiled-coil and C2 domain containing 1B Names coiled-coil and C2 domain-containing protein 1B FRE under dual repression-binding protein 2 five prime repressor element under dual repression-binding protein 2 freud-2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q34

mRNA and Protein(s)

mRNA	Protein	Name
NM_001270984.1	NP_001257913.1	coiled-coil and C2 domain-containing protein 1B

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Cc2d1b	NP_796019.1
Gallus gallus (chicken)	CC2D1B	XP_001235393.2
Homo sapiens (human)	CC2D1B	NP_115825.1
Rattus norvegicus (Norway rat)	Cc2d1b	NP_001257913.1
Xenopus tropicalis (tropical clawed frog)	cc2d1b	XP_002931501.2
	CC2D1B	XP_001105514.1
Pan troglodytes (chimpanzee)	CC2D1B	XP_001144134.2
Canis lupus familiaris (dog)	CC2D1B	XP_005629053.1
Bos taurus (cattle)	CC2D1B	XP_002686449.1
Danio rerio (zebrafish)	cc2d1b	XP_692169.5

Gene Ontology
Bibliography

Related articles in PubMed

5-HT1A receptor gene silencers Freud-1 and Freud-2 are differently expressed in the brain of rats with genetically determined high level of fear-induced aggression or its absence.
Kondaurova EM, Ilchibaeva TV, Tsybko AS, Kozhemyakina RV, Popova NK, Naumenko VS
Behavioural brain research31020-5(2016 09)

Freud-2/CC2D1B mediates dual repression of the serotonin-1A receptor gene.
Hadjighassem MR, Galaraga K, Albert PR
The European journal of neuroscience33(2)214-23(2011 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Freud-1 and Freud-2 levels were different in rats selectively bred for 85 generations for either high level of fear-induced aggression or its absence. Freud-1 protein level was decreased in the hippocampus, whereas Freud-2 protein level was increased in the frontal cortex of highly aggressive rats. There no differences in 5-HT1A receptor gene expression were found in the brains of highly aggressive and nonaggressive rats.
Title: 5-HT1A receptor gene silencers Freud-1 and Freud-2 are differently expressed in the brain of rats with genetically determined high level of fear-induced aggression or its absence.

The following Cc2d1b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cc2d1b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa10019	NM_001270984.1 Latest version!	Rattus norvegicus coiled-coil and C2 domain containing 1B (Cc2d1b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cc2d1b ( NM_001270984.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001257913.1 Rattus norvegicus coiled-coil and C2 domain containing 1B (Cc2d1b), mRNA.

Price & Availability↑

CloneID	ORa10019
Clone ID Related Accession (Same CDS sequence)	NM_001270984.1
Accession Version	NM_001270984.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2553bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-09-22
Organism	Rattus norvegicus(Norway rat)
Product	coiled-coil and C2 domain-containing protein 1B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07049553.1. On Aug 18, 2012 this sequence version replaced XM_233342.6. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGCCAGGGC CAAGACCTCG GAAGGGCCCT AAGACCAGTG GCCAGGGTGC CGAAACTGCC 
AAGCAGCTGG GGCTTTTTGT GGAGTTCAAC CCTGAGGACA TGCTCCTGGG GATGGATGAG 
ACAGAAGATG ATGGAGACCT GGAGGCTGAG TTATTGGCAC TCACTGGGGA AACAGGGAGC 
ACAAGCAGGA AGCCAGCACC CAAGGGGCGG GCCCCACTGC CCATGGCCCA CATTGAGAAG 
TTGGCAGCAG ACTGTATGCG AGATGTGGAG GAGGAGGGCG AGGAAGAGGA AGGGCTGGAG 
GACGATGCAG ACCTTCTGAC AGAGCTGCAG GAAGTCCTGG GTGTGGATGA AGAAACTGGG 
CTGGTGGATG ACAGTGAGGA AACAAGCCCA GACCTGTCTG AGGAGAAGAC AAGGGACAAC 
ACTGAACAAC CTGTAGCACC AGCAGCCTTC CAGCAGGCCT TACCTGCAGC AGTGGCTCAG 
GCTGGAGGGC CTCGGGGGCT GCAGGCTTTG CTGGAGGAAC GGATCCAGAA CTACCGGGAG 
GCTGCGGCCA GTGCCAAGGA GGCTGGTGAA GCTGCCAAAG CCCGGCGCTG TGAGCGAGGC 
CTGAAGACTC TGGAGTCCCA GCTTGCCACT GTGAGGAAAG GCGGCAAGAT CTGTGAGGAC 
GAGATTCCAC CTCCAGTGGC CTTGGGCAAA AGGCCCCCAG CCCACCAGGA AAGACCCAGC 
AAGGACTCTG AGATAGACTC TGCAGGCTCC TGTGCCATGG ACCCAGGTGA CCTTTCCCAA 
CCTGAGTCCA GCCTCCCTGC CGTTGCTGCC TTGCCTGATT CAGACCCAGA CCCACAGGCC 
CTGCTGTTAG CCCGACAAAG AGAGTACAAA GCAGCTGCTC TCAGTGCCAA GCGGGCCGGA 
GATCTAGACC GTGCTCGGGA GCTCATGAGG ATTGGGAAGA GATTTGGTAC TGTCCTAGAG 
GCCCTGGAGA AGGGGCAGCC TGTGGATCTG AGTGGCATGC CCCCAGCACC TGAGGATCTG 
AAGGCCCTCC CCCAGGCTTC TGAGGCCTCT GCAGCAACCC AAGTCCTGTC CCCAGCAGTG 
GAGCAAATGC AGCCAGTGAT GTCCTCTGAC CTCCCAGCCA CCCCAGCGGC CCCTGCAGAG 
CCAAAGACAG TGCTGGATGC TTTACAACAA AGGCTGAACA GGTATCGTGA GGCAGGCATC 
CAGGCCAGGG CCAGTGGGGA TGAGCGCAAA GCCAGGATGC ATGACCGAAT TGCCAAGCAA 
TATCAGGATG CTATTCGAGC TCATCAAGCA GGACGGAAAG TTGACTTTGC TGAGTTACCT 
GTTCCTCCAG GATTTCCTCC CATCCCTGGC CTGGAGCCCA GAAAAGATAC TGAGGAGGAT 
TCAGTGACAG CAACTTTGGC AGCTGCCCAA AAACTGGCCT CAGAAGATAC AGCCCTGGTA 
GATGAAGATG AGGAGAGGGA CACCCCAGCA CAGGCCCCAT TGGCCAAGAA GCCAGCACAG 
CCTCTGGTCC CTTCATCCCA TCTTCTGAAT GAGCCCAAGG CCTCAAGTTC TAAGGAGTCA 
CTGAGTCCAT CTGTTCGGGA GCAGGTGACA CTGCTGGAGG CTCGGAAACT GCAGTACCAG 
CGAGCAGCTC TGCAAGCCAA GCGCAGGCAG GATCTGGAGC AGGCCAAATC CCACTTACGA 
GTAGCTAAAA GTCTTGAGGC TCAGATCATC CAGGCCAGAG CTGGTCAACC GATTGACCTC 
TCTAAGGTGC CTTCACCCTT GACAGATGAA GAAGGTGACT TCATCCTCAT TCACCATGAG 
GATCTTCGAC TCTCCCAGAA GGCTGAGGAG GTGTATGCCC AGCTACAGAA AATACTCCTG 
GAGCAGCACG AGAAGTGCCT GCTGTTCTCC AAGCAGTTCA TGCACCAGGG TAATGTGGCT 
GAGACTACAC GGTTTGAGAA GCTTGCTGAG GACCGAAAGA AACAGCTTGA GATCCTGCAG 
CTGGCCCAAG CCCAGGGCCT GGACCCTCCC AGTCATCACT TTGAATTGAA GACATTGCAG 
ACTGTGAGGA TCTTCTCAGA ACTCAATAGC ACAGAAATGC ATCTGATCAT CGTCCGGGGA 
ATGAACCTCC CAGCCCCACC AGGAGTGACT CCGGATGATT TGGATGCTTT CGTACGGTTT 
GAGTTTCACT ACCCTAACTC GGACCAGGCT CAAAAAAGCA AAACAGCTGT GGTAAAAAAT 
ACGAACTCTC CAGAATTTGA ACAAGTTTTC AAACTAAACA TCAATCGAAA TCACCGAGGC 
TTTAGGAGGG TGATCCAGAG CAAAGGAATC AAATTTGAGA TCTTCCACAA AGGATCCTTT 
TTTAGAAGCG ACAAGCTGGT TGGCACAGCA CACCTGAAAC TGGAAAGGCT GGAGAAAGAG 
TGTGAGATCA GAGAGATCAT GGAGGTTCTG GATGGAAGAA AGCCCACTGG GGGGAAGCTG 
GAAGTTAAGG TGAGGCTGCG GGAGCCTTTG AGCAGCCAGG ACGTGCAGAT GGTCACTGAG 
AACTGGCTGG TCCTGGAGCC TAGGGGCCTG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001257913.1
CDS	151..2703
Translation	MPGPRPRKGPKTSGQGAETAKQLGLFVEFNPEDMLLGMDETEDDGDLEAELLALTGETGSTSRKPAPKGRAPLPMAHIEKLAADCMRDVEEEGEEEEGLEDDADLLTELQEVLGVDEETGLVDDSEETSPDLSEEKTRDNTEQPVAPAAFQQALPAAVAQAGGPRGLQALLEERIQNYREAAASAKEAGEAAKARRCERGLKTLESQLATVRKGGKICEDEIPPPVALGKRPPAHQERPSKDSEIDSAGSCAMDPGDLSQPESSLPAVAALPDSDPDPQALLLARQREYKAAALSAKRAGDLDRARELMRIGKRFGTVLEALEKGQPVDLSGMPPAPEDLKALPQASEASAATQVLSPAVEQMQPVMSSDLPATPAAPAEPKTVLDALQQRLNRYREAGIQARASGDERKARMHDRIAKQYQDAIRAHQAGRKVDFAELPVPPGFPPIPGLEPRKDTEEDSVTATLAAAQKLASEDTALVDEDEERDTPAQAPLAKKPAQPLVPSSHLLNEPKASSSKESLSPSVREQVTLLEARKLQYQRAALQAKRRQDLEQAKSHLRVAKSLEAQIIQARAGQPIDLSKVPSPLTDEEGDFILIHHEDLRLSQKAEEVYAQLQKILLEQHEKCLLFSKQFMHQGNVAETTRFEKLAEDRKKQLEILQLAQAQGLDPPSHHFELKTLQTVRIFSELNSTEMHLIIVRGMNLPAPPGVTPDDLDAFVRFEFHYPNSDQAQKSKTAVVKNTNSPEFEQVFKLNINRNHRGFRRVIQSKGIKFEIFHKGSFFRSDKLVGTAHLKLERLEKECEIREIMEVLDGRKPTGGKLEVKVRLREPLSSQDVQMVTENWLVLEPRGL

Target ORF information:

RefSeq Version	NM_001270984.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus coiled-coil and C2 domain containing 1B (Cc2d1b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001270984.1

ORF Insert Sequence:

ATGCCAGGGC CAAGACCTCG GAAGGGCCCT AAGACCAGTG GCCAGGGTGC CGAAACTGCC 
AAGCAGCTGG GGCTTTTTGT GGAGTTCAAC CCTGAGGACA TGCTCCTGGG GATGGATGAG 
ACAGAAGATG ATGGAGACCT GGAGGCTGAG TTATTGGCAC TCACTGGGGA AACAGGGAGC 
ACAAGCAGGA AGCCAGCACC CAAGGGGCGG GCCCCACTGC CCATGGCCCA CATTGAGAAG 
TTGGCAGCAG ACTGTATGCG AGATGTGGAG GAGGAGGGCG AGGAAGAGGA AGGGCTGGAG 
GACGATGCAG ACCTTCTGAC AGAGCTGCAG GAAGTCCTGG GTGTGGATGA AGAAACTGGG 
CTGGTGGATG ACAGTGAGGA AACAAGCCCA GACCTGTCTG AGGAGAAGAC AAGGGACAAC 
ACTGAACAAC CTGTAGCACC AGCAGCCTTC CAGCAGGCCT TACCTGCAGC AGTGGCTCAG 
GCTGGAGGGC CTCGGGGGCT GCAGGCTTTG CTGGAGGAAC GGATCCAGAA CTACCGGGAG 
GCTGCGGCCA GTGCCAAGGA GGCTGGTGAA GCTGCCAAAG CCCGGCGCTG TGAGCGAGGC 
CTGAAGACTC TGGAGTCCCA GCTTGCCACT GTGAGGAAAG GCGGCAAGAT CTGTGAGGAC 
GAGATTCCAC CTCCAGTGGC CTTGGGCAAA AGGCCCCCAG CCCACCAGGA AAGACCCAGC 
AAGGACTCTG AGATAGACTC TGCAGGCTCC TGTGCCATGG ACCCAGGTGA CCTTTCCCAA 
CCTGAGTCCA GCCTCCCTGC CGTTGCTGCC TTGCCTGATT CAGACCCAGA CCCACAGGCC 
CTGCTGTTAG CCCGACAAAG AGAGTACAAA GCAGCTGCTC TCAGTGCCAA GCGGGCCGGA 
GATCTAGACC GTGCTCGGGA GCTCATGAGG ATTGGGAAGA GATTTGGTAC TGTCCTAGAG 
GCCCTGGAGA AGGGGCAGCC TGTGGATCTG AGTGGCATGC CCCCAGCACC TGAGGATCTG 
AAGGCCCTCC CCCAGGCTTC TGAGGCCTCT GCAGCAACCC AAGTCCTGTC CCCAGCAGTG 
GAGCAAATGC AGCCAGTGAT GTCCTCTGAC CTCCCAGCCA CCCCAGCGGC CCCTGCAGAG 
CCAAAGACAG TGCTGGATGC TTTACAACAA AGGCTGAACA GGTATCGTGA GGCAGGCATC 
CAGGCCAGGG CCAGTGGGGA TGAGCGCAAA GCCAGGATGC ATGACCGAAT TGCCAAGCAA 
TATCAGGATG CTATTCGAGC TCATCAAGCA GGACGGAAAG TTGACTTTGC TGAGTTACCT 
GTTCCTCCAG GATTTCCTCC CATCCCTGGC CTGGAGCCCA GAAAAGATAC TGAGGAGGAT 
TCAGTGACAG CAACTTTGGC AGCTGCCCAA AAACTGGCCT CAGAAGATAC AGCCCTGGTA 
GATGAAGATG AGGAGAGGGA CACCCCAGCA CAGGCCCCAT TGGCCAAGAA GCCAGCACAG 
CCTCTGGTCC CTTCATCCCA TCTTCTGAAT GAGCCCAAGG CCTCAAGTTC TAAGGAGTCA 
CTGAGTCCAT CTGTTCGGGA GCAGGTGACA CTGCTGGAGG CTCGGAAACT GCAGTACCAG 
CGAGCAGCTC TGCAAGCCAA GCGCAGGCAG GATCTGGAGC AGGCCAAATC CCACTTACGA 
GTAGCTAAAA GTCTTGAGGC TCAGATCATC CAGGCCAGAG CTGGTCAACC GATTGACCTC 
TCTAAGGTGC CTTCACCCTT GACAGATGAA GAAGGTGACT TCATCCTCAT TCACCATGAG 
GATCTTCGAC TCTCCCAGAA GGCTGAGGAG GTGTATGCCC AGCTACAGAA AATACTCCTG 
GAGCAGCACG AGAAGTGCCT GCTGTTCTCC AAGCAGTTCA TGCACCAGGG TAATGTGGCT 
GAGACTACAC GGTTTGAGAA GCTTGCTGAG GACCGAAAGA AACAGCTTGA GATCCTGCAG 
CTGGCCCAAG CCCAGGGCCT GGACCCTCCC AGTCATCACT TTGAATTGAA GACATTGCAG 
ACTGTGAGGA TCTTCTCAGA ACTCAATAGC ACAGAAATGC ATCTGATCAT CGTCCGGGGA 
ATGAACCTCC CAGCCCCACC AGGAGTGACT CCGGATGATT TGGATGCTTT CGTACGGTTT 
GAGTTTCACT ACCCTAACTC GGACCAGGCT CAAAAAAGCA AAACAGCTGT GGTAAAAAAT 
ACGAACTCTC CAGAATTTGA ACAAGTTTTC AAACTAAACA TCAATCGAAA TCACCGAGGC 
TTTAGGAGGG TGATCCAGAG CAAAGGAATC AAATTTGAGA TCTTCCACAA AGGATCCTTT 
TTTAGAAGCG ACAAGCTGGT TGGCACAGCA CACCTGAAAC TGGAAAGGCT GGAGAAAGAG 
TGTGAGATCA GAGAGATCAT GGAGGTTCTG GATGGAAGAA AGCCCACTGG GGGGAAGCTG 
GAAGTTAAGG TGAGGCTGCG GGAGCCTTTG AGCAGCCAGG ACGTGCAGAT GGTCACTGAG 
AACTGGCTGG TCCTGGAGCC TAGGGGCCTG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

5-HT1A receptor gene silencers Freud-1 and Freud-2 are differently expressed in the brain of rats with genetically determined high level of fear-induced aggression or its absence.
Behavioural brain research31020-5(2016 09)
Kondaurova EM,Ilchibaeva TV,Tsybko AS,Kozhemyakina RV,Popova NK,Naumenko VS

Freud-2/CC2D1B mediates dual repression of the serotonin-1A receptor gene.
The European journal of neuroscience33(2)214-23(2011 Jan)
Hadjighassem MR,Galaraga K,Albert PR

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Cc2d1b cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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