Hook1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Hook1
Entrez Gene ID	313370
Full Name	hook microtubule-tethering protein 1
General protein information	Preferred Names hook microtubule-tethering protein 1 Names protein Hook homolog 1 hook homolog 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q33

mRNA and Protein(s)

mRNA	Protein	Name
NM_001107946.1	NP_001101416.1	protein Hook homolog 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	HOOK1	XP_513444.2
Mus musculus (house mouse)	Hook1	NP_084290.1
Canis lupus familiaris (dog)	HOOK1	XP_536692.3
Bos taurus (cattle)	LOC785042	NP_001193799.1
Danio rerio (zebrafish)	hook1	NP_001038663.1
Gallus gallus (chicken)	HOOK1	NP_001006542.1
	HOOK1	XP_001082586.1
Rattus norvegicus (Norway rat)	Hook1	NP_001101416.1
Homo sapiens (human)	HOOK1	NP_056972.1

Gene Ontology
Bibliography

Related articles in PubMed

An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex.
Xu L, Sowa ME, Chen J, Li X, Gygi SP, Harper JW
Molecular biology of the cell19(12)5059-71(2008 Dec)

Assembly of spermatid acrosome depends on microtubule organization during mammalian spermiogenesis.
Moreno RD, Palomino J, Schatten G
Developmental biology293(1)218-27(2006 May)

Mammalian late vacuole protein sorting orthologues participate in early endosomal fusion and interact with the cytoskeleton.
Richardson SC, Winistorfer SC, Poupon V, Luzio JP, Piper RC
Molecular biology of the cell15(3)1197-210(2004 Mar)

The Hook1 gene is non-functional in the abnormal spermatozoon head shape (azh) mutant mouse.
Mendoza-Lujambio I, Burfeind P, Dixkens C, Meinhardt A, Hoyer-Fender S, Engel W, Neesen J
Human molecular genetics11(14)1647-58(2002 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Hook1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hook1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06349	NM_001107946.1 Latest version!	Rattus norvegicus hook microtubule-tethering protein 1 (Hook1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Hook1 ( NM_001107946.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101416.1 Rattus norvegicus hook microtubule-tethering protein 1 (Hook1), mRNA.

Price & Availability↑

CloneID	ORa06349
Clone ID Related Accession (Same CDS sequence)	NM_001107946.1
Accession Version	NM_001107946.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2187bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-27
Organism	Rattus norvegicus(Norway rat)
Product	protein Hook homolog 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473998.1. On or before Oct 4, 2007 this sequence version replaced XM_233196.4, XM_001054663.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGAGGACC CGCAGCCGCT GCCACAGCCT GAGCTGCCGC TGTGTGACAG CCTCATCATC 
TGGCTGCAGA CATTTAAGAC TGCCTCACCC TGTCAAGATG TCAAACAGCT GACTAATGGA 
GTGACCATGG CACAAGTTCT TCATCAAATT GACGTAGCTT GGTTCAGCGA ATCTTGGTTA 
AGCCGAATTA AAGATGATGT TGGAGACAAC TGGAGAATAA AGGCTAGTAA CCTAAAGAAG 
GTCCTCCATG GAATTACAAG TTACTATCAT GAGTTTTTGG GGCAGCAGAT TTCTGAAGAA 
CTTATTCCTG ATTTAAATCA AATAACTGAG AGCTCAGATC CTGTGGAGCT TGGGAGATTG 
CTTCAGCTAA TTCTAGGATG CGCAGTCAAC TGTGAGAAGA AACAAGAACA TATTAAAAAT 
ATAATGACCC TGGAAGAATC TGTTCAACAT GTGGTCATGA CTGCAATTCA GGAGTTGATG 
AGTAAAGAAA TAGTGAGCTC TCCTGCAAGT GACGCTGTAG GAGAATTAGA GCAGCAGCTA 
AAAAGGGCTT TAGAAGAGCT TCAGGAGGCC CTAGCAGAAA AGGAAGAGCT GAAGCAGAGG 
TGCCAGGAAC TGGATATGCA GGTAACTGCA CTTCAGGATG AGAAGAATTC CCTGGTCTCT 
GAGAATGAGA TGATGAATGA AAAGCTTGAC CAGTTGGATG GCTCTTTTGA TGACCCAAAT 
ACAATGGTTG CAAAGAAGTA TTTTCACGTA CAGCTGCAAC TAGAACAATT ACAAGAAGAA 
AACTATAGAC TTGAAGCTGC AAAAGATGAT TACCGTGTTC ACTGTGAGGA ACTGGAAAAG 
CAGCTGATTG AATTTCAGCA CAGGAACGAT GAGCTGACGA GCCTTGCTGA GGAGACCAGA 
GCCCTAAAAG ACGAGATAGA TGTTCTTAGG GCTACCTCAG ACAAAGCAAA TAAGCTGGAG 
TCAACAGTGG AGGTGTATCG TCAGAAGCTC CAGGACCTAA ATGACCTCCG CAAGCAGGTG 
AAATCCTTAC AGGAGACAAA TATGATGTAT ATGCACAACA CTGTGAGCTT GGAAGAAGAG 
CTGAAGAAGG CCAATGCAGC TCGTGCACAG CTAGAGACCT ATAAGCGCCA GGTTCAGGAC 
CTTCACACTA AGCTTTCCTC TGAATCCAAA AGGGCAGATA CACTAGCATT CGAAATGAAG 
AGGCTTGAAG AGAAACACGA AACTTTACTC AAGGAAAAAG AGCGATTGAT AGAACAGCGT 
GACACTCTGA AAGAGACGAA TGAGGAGCTG CGGTGCTCAA AAGCACAACA AGATCACCTA 
AATCAAGCTG ATTCATCTGC TACAAAAAGT TATGAAAATC TTGCTGCTGA GATCATGCCA 
GTGGAGTACA GAGAGGTGTT CATTCGACTC CAGCATGAAA ACAAAATGCT TCGCCTGCAG 
CAAGAAGGGA CGGAGAATGA GCGCATCGAG CAGCTGCAGG AGCAGTTGGA ACAGAAACAC 
CGCAAGATGA ACGAGCTGGA AACTGAGCAA AGGTTGAGCA AAGAGCGCAT TGGAGAACTA 
CAGCAGCAAA TTGAGGACCT CCAGAAGTCG TTACAAGAAC AGGGCTCTAA GTCTGAAGGT 
GAAAGTTCCA GCAAATTAAA GCAGAAGTTG GAAGCTCATA TGGAAAAACT AACAGAAGTC 
CATGAAGAAT TACAGAAGAA ACAGGAGCTC ATTGAAGACC TTCAGCCAGA TATAAGTCAG 
AATGCCCAAA AGATCAGTGA ACTTGAAGCG GCTCTTCAGA AGAAAGATGA AGACATGAAA 
GCGATGGAGG AGAGATACAA AATGTACTTA GAGAAAGCCA GGAATGTCAT TAAAACTTTA 
GATCCCAAAT TAAATCCAGC ATCAGCAGAA ATAATGTTAC TGAGAAAGCA GCTGGCGGAG 
AAGGACAGAA GAATTGAAAT TCTAGAGAGT GAATGTAAAG TGGCAAAATT CAGGGATTAT 
GAGGAAAAAC TCATTGTTTC TGCCTGGTAT AACAAGAGCC TGGCCTTTCA GAAACTGGGC 
ATGGAATCTC GGCTGGTGAG CGGTGCTAGT GCTTGCAAAG ACAGCGTCGC GGCTGCTCCC 
GCGCGCTCCT TCTTAGCACA GCAGCGGCAC ATCACCAGCA CCCGAAGAAA CCTCTCTGTG 
AAAGTCCCAG CTGCGGCGTC TGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101416.1
CDS	254..2440
Translation	MEDPQPLPQPELPLCDSLIIWLQTFKTASPCQDVKQLTNGVTMAQVLHQIDVAWFSESWLSRIKDDVGDNWRIKASNLKKVLHGITSYYHEFLGQQISEELIPDLNQITESSDPVELGRLLQLILGCAVNCEKKQEHIKNIMTLEESVQHVVMTAIQELMSKEIVSSPASDAVGELEQQLKRALEELQEALAEKEELKQRCQELDMQVTALQDEKNSLVSENEMMNEKLDQLDGSFDDPNTMVAKKYFHVQLQLEQLQEENYRLEAAKDDYRVHCEELEKQLIEFQHRNDELTSLAEETRALKDEIDVLRATSDKANKLESTVEVYRQKLQDLNDLRKQVKSLQETNMMYMHNTVSLEEELKKANAARAQLETYKRQVQDLHTKLSSESKRADTLAFEMKRLEEKHETLLKEKERLIEQRDTLKETNEELRCSKAQQDHLNQADSSATKSYENLAAEIMPVEYREVFIRLQHENKMLRLQQEGTENERIEQLQEQLEQKHRKMNELETEQRLSKERIGELQQQIEDLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDISQNAQKISELEAALQKKDEDMKAMEERYKMYLEKARNVIKTLDPKLNPASAEIMLLRKQLAEKDRRIEILESECKVAKFRDYEEKLIVSAWYNKSLAFQKLGMESRLVSGASACKDSVAAAPARSFLAQQRHITSTRRNLSVKVPAAASD

Target ORF information:

RefSeq Version	NM_001107946.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus hook microtubule-tethering protein 1 (Hook1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001107946.1

ORF Insert Sequence:

ATGGAGGACC CGCAGCCGCT GCCACAGCCT GAGCTGCCGC TGTGTGACAG CCTCATCATC 
TGGCTGCAGA CATTTAAGAC TGCCTCACCC TGTCAAGATG TCAAACAGCT GACTAATGGA 
GTGACCATGG CACAAGTTCT TCATCAAATT GACGTAGCTT GGTTCAGCGA ATCTTGGTTA 
AGCCGAATTA AAGATGATGT TGGAGACAAC TGGAGAATAA AGGCTAGTAA CCTAAAGAAG 
GTCCTCCATG GAATTACAAG TTACTATCAT GAGTTTTTGG GGCAGCAGAT TTCTGAAGAA 
CTTATTCCTG ATTTAAATCA AATAACTGAG AGCTCAGATC CTGTGGAGCT TGGGAGATTG 
CTTCAGCTAA TTCTAGGATG CGCAGTCAAC TGTGAGAAGA AACAAGAACA TATTAAAAAT 
ATAATGACCC TGGAAGAATC TGTTCAACAT GTGGTCATGA CTGCAATTCA GGAGTTGATG 
AGTAAAGAAA TAGTGAGCTC TCCTGCAAGT GACGCTGTAG GAGAATTAGA GCAGCAGCTA 
AAAAGGGCTT TAGAAGAGCT TCAGGAGGCC CTAGCAGAAA AGGAAGAGCT GAAGCAGAGG 
TGCCAGGAAC TGGATATGCA GGTAACTGCA CTTCAGGATG AGAAGAATTC CCTGGTCTCT 
GAGAATGAGA TGATGAATGA AAAGCTTGAC CAGTTGGATG GCTCTTTTGA TGACCCAAAT 
ACAATGGTTG CAAAGAAGTA TTTTCACGTA CAGCTGCAAC TAGAACAATT ACAAGAAGAA 
AACTATAGAC TTGAAGCTGC AAAAGATGAT TACCGTGTTC ACTGTGAGGA ACTGGAAAAG 
CAGCTGATTG AATTTCAGCA CAGGAACGAT GAGCTGACGA GCCTTGCTGA GGAGACCAGA 
GCCCTAAAAG ACGAGATAGA TGTTCTTAGG GCTACCTCAG ACAAAGCAAA TAAGCTGGAG 
TCAACAGTGG AGGTGTATCG TCAGAAGCTC CAGGACCTAA ATGACCTCCG CAAGCAGGTG 
AAATCCTTAC AGGAGACAAA TATGATGTAT ATGCACAACA CTGTGAGCTT GGAAGAAGAG 
CTGAAGAAGG CCAATGCAGC TCGTGCACAG CTAGAGACCT ATAAGCGCCA GGTTCAGGAC 
CTTCACACTA AGCTTTCCTC TGAATCCAAA AGGGCAGATA CACTAGCATT CGAAATGAAG 
AGGCTTGAAG AGAAACACGA AACTTTACTC AAGGAAAAAG AGCGATTGAT AGAACAGCGT 
GACACTCTGA AAGAGACGAA TGAGGAGCTG CGGTGCTCAA AAGCACAACA AGATCACCTA 
AATCAAGCTG ATTCATCTGC TACAAAAAGT TATGAAAATC TTGCTGCTGA GATCATGCCA 
GTGGAGTACA GAGAGGTGTT CATTCGACTC CAGCATGAAA ACAAAATGCT TCGCCTGCAG 
CAAGAAGGGA CGGAGAATGA GCGCATCGAG CAGCTGCAGG AGCAGTTGGA ACAGAAACAC 
CGCAAGATGA ACGAGCTGGA AACTGAGCAA AGGTTGAGCA AAGAGCGCAT TGGAGAACTA 
CAGCAGCAAA TTGAGGACCT CCAGAAGTCG TTACAAGAAC AGGGCTCTAA GTCTGAAGGT 
GAAAGTTCCA GCAAATTAAA GCAGAAGTTG GAAGCTCATA TGGAAAAACT AACAGAAGTC 
CATGAAGAAT TACAGAAGAA ACAGGAGCTC ATTGAAGACC TTCAGCCAGA TATAAGTCAG 
AATGCCCAAA AGATCAGTGA ACTTGAAGCG GCTCTTCAGA AGAAAGATGA AGACATGAAA 
GCGATGGAGG AGAGATACAA AATGTACTTA GAGAAAGCCA GGAATGTCAT TAAAACTTTA 
GATCCCAAAT TAAATCCAGC ATCAGCAGAA ATAATGTTAC TGAGAAAGCA GCTGGCGGAG 
AAGGACAGAA GAATTGAAAT TCTAGAGAGT GAATGTAAAG TGGCAAAATT CAGGGATTAT 
GAGGAAAAAC TCATTGTTTC TGCCTGGTAT AACAAGAGCC TGGCCTTTCA GAAACTGGGC 
ATGGAATCTC GGCTGGTGAG CGGTGCTAGT GCTTGCAAAG ACAGCGTCGC GGCTGCTCCC 
GCGCGCTCCT TCTTAGCACA GCAGCGGCAC ATCACCAGCA CCCGAAGAAA CCTCTCTGTG 
AAAGTCCCAG CTGCGGCGTC TGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex.
Molecular biology of the cell19(12)5059-71(2008 Dec)
Xu L,Sowa ME,Chen J,Li X,Gygi SP,Harper JW

Assembly of spermatid acrosome depends on microtubule organization during mammalian spermiogenesis.
Developmental biology293(1)218-27(2006 May)
Moreno RD,Palomino J,Schatten G

Mammalian late vacuole protein sorting orthologues participate in early endosomal fusion and interact with the cytoskeleton.
Molecular biology of the cell15(3)1197-210(2004 Mar)
Richardson SC,Winistorfer SC,Poupon V,Luzio JP,Piper RC

The Hook1 gene is non-functional in the abnormal spermatozoon head shape (azh) mutant mouse.
Human molecular genetics11(14)1647-58(2002 Jul)
Mendoza-Lujambio I,Burfeind P,Dixkens C,Meinhardt A,Hoyer-Fender S,Engel W,Neesen J

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Hook1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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