Lrrc8a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lrrc8a
Entrez Gene ID	311846
Full Name	leucine rich repeat containing 8 VRAC subunit A
Synonyms	Lrrc8
General protein information	Preferred Names leucine rich repeat containing 8 VRAC subunit A Names volume-regulated anion channel subunit LRRC8A leucine rich repeat containing 8 family, member A leucine rich repeat containing 8A leucine-rich repeat-containing 8 leucine-rich repeat-containing protein 8A
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3p12

mRNA and Protein(s)

mRNA	Protein	Name
XM_017591843.1	XP_017447332.1	volume-regulated anion channel subunit LRRC8A isoform X1
NM_001024782.1	NP_001019953.1	volume-regulated anion channel subunit LRRC8A
XM_017591840.1	XP_017447329.1	volume-regulated anion channel subunit LRRC8A isoform X1
XM_017591842.1	XP_017447331.1	volume-regulated anion channel subunit LRRC8A isoform X1
XM_017591841.1	XP_017447330.1	volume-regulated anion channel subunit LRRC8A isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	LRRC8A	NP_001120717.1
Bos taurus (cattle)	LRRC8A	NP_001070275.1
Danio rerio (zebrafish)	lrrc8a	NP_001025120.1
Danio rerio (zebrafish)	si:ch211-236k19.7	XP_005165659.1
Xenopus tropicalis (tropical clawed frog)	lrrc8a	XP_004916747.1
	LRRC8A	XP_001109698.1
Mus musculus (house mouse)	Lrrc8a	NP_808393.1
Gallus gallus (chicken)	LOC100858917	XP_003642331.1
Gallus gallus (chicken)	LRRC8A	XP_415484.1
Pan troglodytes (chimpanzee)	LRRC8A	XP_520301.1
Canis lupus familiaris (dog)	LRRC8A	XP_005625321.1
Rattus norvegicus (Norway rat)	Lrrc8a	NP_001019953.1

Gene Ontology
Bibliography

Related articles in PubMed

Molecular composition and heterogeneity of the LRRC8-containing swelling-activated osmolyte channels in primary rat astrocytes.
Schober AL, Wilson CS, Mongin AA
The Journal of physiology595(22)6939-6951(2017 Nov)

LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength.
Syeda R, Qiu Z, Dubin AE, Murthy SE, Florendo MN, Mason DE, Mathur J, Cahalan SM, Peters EC, Montal M, Patapoutian A
Cell164(3)499-511(2016 Jan)

Identification of LRRC8 heteromers as an essential component of the volume-regulated anion channel VRAC.
Voss FK, Ullrich F, M?nch J, Lazarow K, Lutter D, Mah N, Andrade-Navarro MA, von Kries JP, Stauber T, Jentsch TJ
Science (New York, N.Y.)344(6184)634-8(2014 May)

SWELL1, a plasma membrane protein, is an essential component of volume-regulated anion channel.
Qiu Z, Dubin AE, Mathur J, Tu B, Reddy K, Miraglia LJ, Reinhardt J, Orth AP, Patapoutian A
Cell157(2)447-458(2014 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Lrrc8a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lrrc8a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa06648	NM_001024782.1 Latest version!	Rattus norvegicus leucine rich repeat containing 8 VRAC subunit A (Lrrc8a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00
ORa06648	XM_017591840.1 Latest version!	Rattus norvegicus leucine rich repeat containing 8 family, member A (Lrrc8a), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00
ORa06648	XM_017591843.1 Latest version!	Rattus norvegicus leucine rich repeat containing 8 family, member A (Lrrc8a), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00
ORa06648	XM_017591841.1 Latest version!	Rattus norvegicus leucine rich repeat containing 8 family, member A (Lrrc8a), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00
ORa06648	XM_017591842.1 Latest version!	Rattus norvegicus leucine rich repeat containing 8 family, member A (Lrrc8a), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lrrc8a ( NM_001024782.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001019953.1 Rattus norvegicus leucine rich repeat containing 8 VRAC subunit A (Lrrc8a), mRNA.

Price & Availability↑

CloneID	ORa06648
Clone ID Related Accession (Same CDS sequence)	XM_017591843.1 , NM_001024782.1 , XM_017591840.1 , XM_017591842.1 , XM_017591841.1
Accession Version	NM_001024782.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2433bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	volume-regulated anion channel subunit LRRC8A
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC097371.1. On Jun 10, 2005 this sequence version replaced XM_231120.3. ##Evidence-Data-START## Transcript exon combination :: BC097371.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGATTCCGG TGACAGAGCT CCGCTACTTC GCGGACACGC AGCCAGCATA CCGGATCCTG 
AAGCCGTGGT GGGATGTGTT CACTGACTAC ATCTCCATTG TCATGCTGAT GATTGCTGTC 
TTTGGGGGGA CACTGCAAGT CACCCAGGAC AAGATGATCT GCCTACCTTG TAAGTGGGTC 
ACCAAAGACT CCTGCAACGA CTCCTTCCGG GGCTGGGGGG CCTCCAGCCC AGAGCCCACT 
TACCCCAACT CCACAGTCCT GCCTACTCCT GACACGGGCC CCACAGGTAT CAAGTATGAC 
CTAGATCGCC ACCAGTACAA CTACGTGGAT GCCGTGTGTT ACGAGAACCG CCTGCATTGG 
TTTGCCAAGT ACTTCCCCTA CCTCGTGCTC CTGCACACCC TCATCTTCCT GGCCTGCAGC 
AACTTCTGGT TCAAGTTCCC ACGCACCAGC TCGAAGCTGG AGCACTTCGT GTCTATCCTG 
CTCAAGTGCT TTGATTCGCC ATGGACCACA CGGGCCCTGT CAGAGACAGT AGTGGAGGAG 
AGTGACCCCA AGCCAGCCTT CAGCAAGATG AATGGCTCCA TGGACAAGAA GTCATCCACG 
GTCAGTGAGG ATGTGGAGGC CACTGTGCCC ATGCTGCAGC GGACCAAGTC ACGGATTGAG 
CAGGGCATCG TGGACCGCTC CGAGACAGGT GTGCTGGACA AGAAGGAAGG GGAGCAGGCG 
AAGGCACTGT TTGAGAAGGT GAAGAAGTTC CGGACCCATG TGGAGGAGGG GGACATCGTG 
TACCGCCTCT ACATGCGGCA GACCATCATC AAGGTGATCA AGTTCTTCCT CATCATCTGC 
TACACCGTGT ACTATGTGCA CAACATCAAG TTTGACGTGG ACTGCACCGT GGACATCGAG 
AGCCTGACAG GCTACCGCAC CTACCGCTGT GCCCACCCTC TGGCCACCCT CTTCAAGATC 
CTGGCATCCT TCTACATCAG CCTGGTCATC TTCTACGGCC TCATCTGCAT GTACACCCTG 
TGGTGGATGC TCCGGCGCTC CCTCAAGAAG TACTCGTTTG AGTCGATCCG AGAGGAGAGC 
AGCTACAGCG ACATCCCAGA CGTCAAGAAT GACTTCGCCT TCATGTTGCA CCTCATTGAC 
CAGTATGACC CTCTCTACTC AAAGCGCTTC GCCGTCTTCC TGTCTGAGGT GAGTGAGAAC 
AAGCTGCGTC AGCTGAACCT CAACAACGAG TGGACGCTGG ACAAGCTGCG CCAGCGGCTC 
ACCAAAAACG CCCAGGACAA GCTGGAGCTG CACCTCTTCA TGCTGAGCGG CATCCCGGAC 
ACCGTGTTTG ACCTGCTGGA GTTAGAGGTC CTGAAGCTGG AACTGATCCC CGACGTGACC 
ATCCCGCCCA GCATCGCCCA GCTCACAGGC CTCAAGGAGC TCTGGCTGTA CCACACGGCA 
GCCAAGATCG AGGCTCCCGC CCTGGCCTTC CTGCGAGAGA ACCTGCGGGC GCTGCACATC 
AAGTTCACTG ACATCAAGGA GATCCCACTG TGGATCTACA GCCTGAAGAC ACTGGAGGAG 
CTGCACTTGA CAGGCAACCT GAGCGCAGAG AACAACCGCT ACATCGTCAT TGACGGACTG 
CGGGAGCTCA AACGCCTTAA GGTGCTGCGG CTCAAAAGCA ACCTGAGCAA GCTGCCGCAG 
GTGGTCACGG ACGTGGGCGT GCACCTGCAG AAGCTGTCCA TCAACAATGA GGGCACCAAG 
CTCATCGTCC TCAACAGCCT CAAGAAGATG GTTAACCTGA CAGAGCTGGA GCTGATCCGC 
TGCGACCTGG AGCGTATCCC TCACTCCATC TTTAGCCTCC ACAACCTGCA GGAGATCGAC 
CTGAAGGACA ACAACCTCAA GACCATCGAG GAGATCATCA GCTTCCAGCA TCTGCACCGC 
CTCACCTGCC TTAAGCTGTG GTACAACCAC ATCGCCTACA TCCCCATCCA GATCGGCAAC 
CTCACCAACC TTGAGCGCCT CTACCTGAAC CGCAACAAAA TCGAGAAAAT TCCCACCCAG 
CTCTTCTACT GCCGCAAGCT GCGCTACCTG GACCTCAGCC ACAACAACCT GACCTTGCTC 
CCCGCTGACA TTGGCCTCTT GCAGAACCTC CAGAACCTGG CCGTCACAGC CAATAGGATC 
GAGGCGCTCC CCCCGGAGCT CTTCCAGTGT CGGAAGCTGC GGGCTCTACA CCTGGGCAAC 
AATGTTCTGC AGTCACTGCC CTCGAGAGTG GGTGAGCTGA CCAACCTGAC GCAGATTGAG 
CTTCGGGGCA ACCGGCTGGA GTGCCTGCCC GTGGAGCTGG GCGAGTGTCC CCTGCTCAAG 
CGCAGCGGCC TGGTGGTAGA GGAGGACTTG TTCAGCACAC TGCCGCCTGA GGTGAAGGAA 
CGGCTCTGGA GAGCTGACAA GGAGCAGGCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001019953.1
CDS	164..2596
Translation	MIPVTELRYFADTQPAYRILKPWWDVFTDYISIVMLMIAVFGGTLQVTQDKMICLPCKWVTKDSCNDSFRGWGASSPEPTYPNSTVLPTPDTGPTGIKYDLDRHQYNYVDAVCYENRLHWFAKYFPYLVLLHTLIFLACSNFWFKFPRTSSKLEHFVSILLKCFDSPWTTRALSETVVEESDPKPAFSKMNGSMDKKSSTVSEDVEATVPMLQRTKSRIEQGIVDRSETGVLDKKEGEQAKALFEKVKKFRTHVEEGDIVYRLYMRQTIIKVIKFFLIICYTVYYVHNIKFDVDCTVDIESLTGYRTYRCAHPLATLFKILASFYISLVIFYGLICMYTLWWMLRRSLKKYSFESIREESSYSDIPDVKNDFAFMLHLIDQYDPLYSKRFAVFLSEVSENKLRQLNLNNEWTLDKLRQRLTKNAQDKLELHLFMLSGIPDTVFDLLELEVLKLELIPDVTIPPSIAQLTGLKELWLYHTAAKIEAPALAFLRENLRALHIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGLRELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMVNLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTLLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLKRSGLVVEEDLFSTLPPEVKERLWRADKEQA

Target ORF information:

RefSeq Version	NM_001024782.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus leucine rich repeat containing 8 VRAC subunit A (Lrrc8a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001024782.1

ORF Insert Sequence:

ATGATTCCGG TGACAGAGCT CCGCTACTTC GCGGACACGC AGCCAGCATA CCGGATCCTG 
AAGCCGTGGT GGGATGTGTT CACTGACTAC ATCTCCATTG TCATGCTGAT GATTGCTGTC 
TTTGGGGGGA CACTGCAAGT CACCCAGGAC AAGATGATCT GCCTACCTTG TAAGTGGGTC 
ACCAAAGACT CCTGCAACGA CTCCTTCCGG GGCTGGGGGG CCTCCAGCCC AGAGCCCACT 
TACCCCAACT CCACAGTCCT GCCTACTCCT GACACGGGCC CCACAGGTAT CAAGTATGAC 
CTAGATCGCC ACCAGTACAA CTACGTGGAT GCCGTGTGTT ACGAGAACCG CCTGCATTGG 
TTTGCCAAGT ACTTCCCCTA CCTCGTGCTC CTGCACACCC TCATCTTCCT GGCCTGCAGC 
AACTTCTGGT TCAAGTTCCC ACGCACCAGC TCGAAGCTGG AGCACTTCGT GTCTATCCTG 
CTCAAGTGCT TTGATTCGCC ATGGACCACA CGGGCCCTGT CAGAGACAGT AGTGGAGGAG 
AGTGACCCCA AGCCAGCCTT CAGCAAGATG AATGGCTCCA TGGACAAGAA GTCATCCACG 
GTCAGTGAGG ATGTGGAGGC CACTGTGCCC ATGCTGCAGC GGACCAAGTC ACGGATTGAG 
CAGGGCATCG TGGACCGCTC CGAGACAGGT GTGCTGGACA AGAAGGAAGG GGAGCAGGCG 
AAGGCACTGT TTGAGAAGGT GAAGAAGTTC CGGACCCATG TGGAGGAGGG GGACATCGTG 
TACCGCCTCT ACATGCGGCA GACCATCATC AAGGTGATCA AGTTCTTCCT CATCATCTGC 
TACACCGTGT ACTATGTGCA CAACATCAAG TTTGACGTGG ACTGCACCGT GGACATCGAG 
AGCCTGACAG GCTACCGCAC CTACCGCTGT GCCCACCCTC TGGCCACCCT CTTCAAGATC 
CTGGCATCCT TCTACATCAG CCTGGTCATC TTCTACGGCC TCATCTGCAT GTACACCCTG 
TGGTGGATGC TCCGGCGCTC CCTCAAGAAG TACTCGTTTG AGTCGATCCG AGAGGAGAGC 
AGCTACAGCG ACATCCCAGA CGTCAAGAAT GACTTCGCCT TCATGTTGCA CCTCATTGAC 
CAGTATGACC CTCTCTACTC AAAGCGCTTC GCCGTCTTCC TGTCTGAGGT GAGTGAGAAC 
AAGCTGCGTC AGCTGAACCT CAACAACGAG TGGACGCTGG ACAAGCTGCG CCAGCGGCTC 
ACCAAAAACG CCCAGGACAA GCTGGAGCTG CACCTCTTCA TGCTGAGCGG CATCCCGGAC 
ACCGTGTTTG ACCTGCTGGA GTTAGAGGTC CTGAAGCTGG AACTGATCCC CGACGTGACC 
ATCCCGCCCA GCATCGCCCA GCTCACAGGC CTCAAGGAGC TCTGGCTGTA CCACACGGCA 
GCCAAGATCG AGGCTCCCGC CCTGGCCTTC CTGCGAGAGA ACCTGCGGGC GCTGCACATC 
AAGTTCACTG ACATCAAGGA GATCCCACTG TGGATCTACA GCCTGAAGAC ACTGGAGGAG 
CTGCACTTGA CAGGCAACCT GAGCGCAGAG AACAACCGCT ACATCGTCAT TGACGGACTG 
CGGGAGCTCA AACGCCTTAA GGTGCTGCGG CTCAAAAGCA ACCTGAGCAA GCTGCCGCAG 
GTGGTCACGG ACGTGGGCGT GCACCTGCAG AAGCTGTCCA TCAACAATGA GGGCACCAAG 
CTCATCGTCC TCAACAGCCT CAAGAAGATG GTTAACCTGA CAGAGCTGGA GCTGATCCGC 
TGCGACCTGG AGCGTATCCC TCACTCCATC TTTAGCCTCC ACAACCTGCA GGAGATCGAC 
CTGAAGGACA ACAACCTCAA GACCATCGAG GAGATCATCA GCTTCCAGCA TCTGCACCGC 
CTCACCTGCC TTAAGCTGTG GTACAACCAC ATCGCCTACA TCCCCATCCA GATCGGCAAC 
CTCACCAACC TTGAGCGCCT CTACCTGAAC CGCAACAAAA TCGAGAAAAT TCCCACCCAG 
CTCTTCTACT GCCGCAAGCT GCGCTACCTG GACCTCAGCC ACAACAACCT GACCTTGCTC 
CCCGCTGACA TTGGCCTCTT GCAGAACCTC CAGAACCTGG CCGTCACAGC CAATAGGATC 
GAGGCGCTCC CCCCGGAGCT CTTCCAGTGT CGGAAGCTGC GGGCTCTACA CCTGGGCAAC 
AATGTTCTGC AGTCACTGCC CTCGAGAGTG GGTGAGCTGA CCAACCTGAC GCAGATTGAG 
CTTCGGGGCA ACCGGCTGGA GTGCCTGCCC GTGGAGCTGG GCGAGTGTCC CCTGCTCAAG 
CGCAGCGGCC TGGTGGTAGA GGAGGACTTG TTCAGCACAC TGCCGCCTGA GGTGAAGGAA 
CGGCTCTGGA GAGCTGACAA GGAGCAGGCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lrrc8a ( XM_017591843.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017447332.1 Rattus norvegicus leucine rich repeat containing 8 family, member A (Lrrc8a), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa06648
Clone ID Related Accession (Same CDS sequence)	XM_017591843.1 , NM_001024782.1 , XM_017591840.1 , XM_017591842.1 , XM_017591841.1
Accession Version	XM_017591843.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2433bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	volume-regulated anion channel subunit LRRC8A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATTCCGG TGACAGAGCT CCGCTACTTC GCGGACACGC AGCCAGCATA CCGGATCCTG 
AAGCCGTGGT GGGATGTGTT CACTGACTAC ATCTCCATTG TCATGCTGAT GATTGCTGTC 
TTTGGGGGGA CACTGCAAGT CACCCAGGAC AAGATGATCT GCCTACCTTG TAAGTGGGTC 
ACCAAAGACT CCTGCAACGA CTCCTTCCGG GGCTGGGGGG CCTCCAGCCC AGAGCCCACT 
TACCCCAACT CCACAGTCCT GCCTACTCCT GACACGGGCC CCACAGGTAT CAAGTATGAC 
CTAGATCGCC ACCAGTACAA CTACGTGGAT GCCGTGTGTT ACGAGAACCG CCTGCATTGG 
TTTGCCAAGT ACTTCCCCTA CCTCGTGCTC CTGCACACCC TCATCTTCCT GGCCTGCAGC 
AACTTCTGGT TCAAGTTCCC ACGCACCAGC TCGAAGCTGG AGCACTTCGT GTCTATCCTG 
CTCAAGTGCT TTGATTCGCC ATGGACCACA CGGGCCCTGT CAGAGACAGT AGTGGAGGAG 
AGTGACCCCA AGCCAGCCTT CAGCAAGATG AATGGCTCCA TGGACAAGAA GTCATCCACG 
GTCAGTGAGG ATGTGGAGGC CACTGTGCCC ATGCTGCAGC GGACCAAGTC ACGGATTGAG 
CAGGGCATCG TGGACCGCTC CGAGACAGGT GTGCTGGACA AGAAGGAAGG GGAGCAGGCG 
AAGGCACTGT TTGAGAAGGT GAAGAAGTTC CGGACCCATG TGGAGGAGGG GGACATCGTG 
TACCGCCTCT ACATGCGGCA GACCATCATC AAGGTGATCA AGTTCTTCCT CATCATCTGC 
TACACCGTGT ACTATGTGCA CAACATCAAG TTTGACGTGG ACTGCACCGT GGACATCGAG 
AGCCTGACAG GCTACCGCAC CTACCGCTGT GCCCACCCTC TGGCCACCCT CTTCAAGATC 
CTGGCATCCT TCTACATCAG CCTGGTCATC TTCTACGGCC TCATCTGCAT GTACACCCTG 
TGGTGGATGC TCCGGCGCTC CCTCAAGAAG TACTCGTTTG AGTCGATCCG AGAGGAGAGC 
AGCTACAGCG ACATCCCAGA CGTCAAGAAT GACTTCGCCT TCATGTTGCA CCTCATTGAC 
CAGTATGACC CTCTCTACTC AAAGCGCTTC GCCGTCTTCC TGTCTGAGGT GAGTGAGAAC 
AAGCTGCGTC AGCTGAACCT CAACAACGAG TGGACGCTGG ACAAGCTGCG CCAGCGGCTC 
ACCAAAAACG CCCAGGACAA GCTGGAGCTG CACCTCTTCA TGCTGAGCGG CATCCCGGAC 
ACCGTGTTTG ACCTGCTGGA GTTAGAGGTC CTGAAGCTGG AACTGATCCC CGACGTGACC 
ATCCCGCCCA GCATCGCCCA GCTCACAGGC CTCAAGGAGC TCTGGCTGTA CCACACGGCA 
GCCAAGATCG AGGCTCCCGC CCTGGCCTTC CTGCGAGAGA ACCTGCGGGC GCTGCACATC 
AAGTTCACTG ACATCAAGGA GATCCCACTG TGGATCTACA GCCTGAAGAC ACTGGAGGAG 
CTGCACTTGA CAGGCAACCT GAGCGCAGAG AACAACCGCT ACATCGTCAT TGACGGACTG 
CGGGAGCTCA AACGCCTTAA GGTGCTGCGG CTCAAAAGCA ACCTGAGCAA GCTGCCGCAG 
GTGGTCACGG ACGTGGGCGT GCACCTGCAG AAGCTGTCCA TCAACAATGA GGGCACCAAG 
CTCATCGTCC TCAACAGCCT CAAGAAGATG GTTAACCTGA CAGAGCTGGA GCTGATCCGC 
TGCGACCTGG AGCGTATCCC TCACTCCATC TTTAGCCTCC ACAACCTGCA GGAGATCGAC 
CTGAAGGACA ACAACCTCAA GACCATCGAG GAGATCATCA GCTTCCAGCA TCTGCACCGC 
CTCACCTGCC TTAAGCTGTG GTACAACCAC ATCGCCTACA TCCCCATCCA GATCGGCAAC 
CTCACCAACC TTGAGCGCCT CTACCTGAAC CGCAACAAAA TCGAGAAAAT TCCCACCCAG 
CTCTTCTACT GCCGCAAGCT GCGCTACCTG GACCTCAGCC ACAACAACCT GACCTTGCTC 
CCCGCTGACA TTGGCCTCTT GCAGAACCTC CAGAACCTGG CCGTCACAGC CAATAGGATC 
GAGGCGCTCC CCCCGGAGCT CTTCCAGTGT CGGAAGCTGC GGGCTCTACA CCTGGGCAAC 
AATGTTCTGC AGTCACTGCC CTCGAGAGTG GGTGAGCTGA CCAACCTGAC GCAGATTGAG 
CTTCGGGGCA ACCGGCTGGA GTGCCTGCCC GTGGAGCTGG GCGAGTGTCC CCTGCTCAAG 
CGCAGCGGCC TGGTGGTAGA GGAGGACTTG TTCAGCACAC TGCCGCCTGA GGTGAAGGAA 
CGGCTCTGGA GAGCTGACAA GGAGCAGGCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017447332.1
CDS	600..3032
Translation	MIPVTELRYFADTQPAYRILKPWWDVFTDYISIVMLMIAVFGGTLQVTQDKMICLPCKWVTKDSCNDSFRGWGASSPEPTYPNSTVLPTPDTGPTGIKYDLDRHQYNYVDAVCYENRLHWFAKYFPYLVLLHTLIFLACSNFWFKFPRTSSKLEHFVSILLKCFDSPWTTRALSETVVEESDPKPAFSKMNGSMDKKSSTVSEDVEATVPMLQRTKSRIEQGIVDRSETGVLDKKEGEQAKALFEKVKKFRTHVEEGDIVYRLYMRQTIIKVIKFFLIICYTVYYVHNIKFDVDCTVDIESLTGYRTYRCAHPLATLFKILASFYISLVIFYGLICMYTLWWMLRRSLKKYSFESIREESSYSDIPDVKNDFAFMLHLIDQYDPLYSKRFAVFLSEVSENKLRQLNLNNEWTLDKLRQRLTKNAQDKLELHLFMLSGIPDTVFDLLELEVLKLELIPDVTIPPSIAQLTGLKELWLYHTAAKIEAPALAFLRENLRALHIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGLRELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMVNLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTLLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLKRSGLVVEEDLFSTLPPEVKERLWRADKEQA

Target ORF information:

RefSeq Version	XM_017591843.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus leucine rich repeat containing 8 family, member A (Lrrc8a), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017591843.1

ORF Insert Sequence:

ATGATTCCGG TGACAGAGCT CCGCTACTTC GCGGACACGC AGCCAGCATA CCGGATCCTG 
AAGCCGTGGT GGGATGTGTT CACTGACTAC ATCTCCATTG TCATGCTGAT GATTGCTGTC 
TTTGGGGGGA CACTGCAAGT CACCCAGGAC AAGATGATCT GCCTACCTTG TAAGTGGGTC 
ACCAAAGACT CCTGCAACGA CTCCTTCCGG GGCTGGGGGG CCTCCAGCCC AGAGCCCACT 
TACCCCAACT CCACAGTCCT GCCTACTCCT GACACGGGCC CCACAGGTAT CAAGTATGAC 
CTAGATCGCC ACCAGTACAA CTACGTGGAT GCCGTGTGTT ACGAGAACCG CCTGCATTGG 
TTTGCCAAGT ACTTCCCCTA CCTCGTGCTC CTGCACACCC TCATCTTCCT GGCCTGCAGC 
AACTTCTGGT TCAAGTTCCC ACGCACCAGC TCGAAGCTGG AGCACTTCGT GTCTATCCTG 
CTCAAGTGCT TTGATTCGCC ATGGACCACA CGGGCCCTGT CAGAGACAGT AGTGGAGGAG 
AGTGACCCCA AGCCAGCCTT CAGCAAGATG AATGGCTCCA TGGACAAGAA GTCATCCACG 
GTCAGTGAGG ATGTGGAGGC CACTGTGCCC ATGCTGCAGC GGACCAAGTC ACGGATTGAG 
CAGGGCATCG TGGACCGCTC CGAGACAGGT GTGCTGGACA AGAAGGAAGG GGAGCAGGCG 
AAGGCACTGT TTGAGAAGGT GAAGAAGTTC CGGACCCATG TGGAGGAGGG GGACATCGTG 
TACCGCCTCT ACATGCGGCA GACCATCATC AAGGTGATCA AGTTCTTCCT CATCATCTGC 
TACACCGTGT ACTATGTGCA CAACATCAAG TTTGACGTGG ACTGCACCGT GGACATCGAG 
AGCCTGACAG GCTACCGCAC CTACCGCTGT GCCCACCCTC TGGCCACCCT CTTCAAGATC 
CTGGCATCCT TCTACATCAG CCTGGTCATC TTCTACGGCC TCATCTGCAT GTACACCCTG 
TGGTGGATGC TCCGGCGCTC CCTCAAGAAG TACTCGTTTG AGTCGATCCG AGAGGAGAGC 
AGCTACAGCG ACATCCCAGA CGTCAAGAAT GACTTCGCCT TCATGTTGCA CCTCATTGAC 
CAGTATGACC CTCTCTACTC AAAGCGCTTC GCCGTCTTCC TGTCTGAGGT GAGTGAGAAC 
AAGCTGCGTC AGCTGAACCT CAACAACGAG TGGACGCTGG ACAAGCTGCG CCAGCGGCTC 
ACCAAAAACG CCCAGGACAA GCTGGAGCTG CACCTCTTCA TGCTGAGCGG CATCCCGGAC 
ACCGTGTTTG ACCTGCTGGA GTTAGAGGTC CTGAAGCTGG AACTGATCCC CGACGTGACC 
ATCCCGCCCA GCATCGCCCA GCTCACAGGC CTCAAGGAGC TCTGGCTGTA CCACACGGCA 
GCCAAGATCG AGGCTCCCGC CCTGGCCTTC CTGCGAGAGA ACCTGCGGGC GCTGCACATC 
AAGTTCACTG ACATCAAGGA GATCCCACTG TGGATCTACA GCCTGAAGAC ACTGGAGGAG 
CTGCACTTGA CAGGCAACCT GAGCGCAGAG AACAACCGCT ACATCGTCAT TGACGGACTG 
CGGGAGCTCA AACGCCTTAA GGTGCTGCGG CTCAAAAGCA ACCTGAGCAA GCTGCCGCAG 
GTGGTCACGG ACGTGGGCGT GCACCTGCAG AAGCTGTCCA TCAACAATGA GGGCACCAAG 
CTCATCGTCC TCAACAGCCT CAAGAAGATG GTTAACCTGA CAGAGCTGGA GCTGATCCGC 
TGCGACCTGG AGCGTATCCC TCACTCCATC TTTAGCCTCC ACAACCTGCA GGAGATCGAC 
CTGAAGGACA ACAACCTCAA GACCATCGAG GAGATCATCA GCTTCCAGCA TCTGCACCGC 
CTCACCTGCC TTAAGCTGTG GTACAACCAC ATCGCCTACA TCCCCATCCA GATCGGCAAC 
CTCACCAACC TTGAGCGCCT CTACCTGAAC CGCAACAAAA TCGAGAAAAT TCCCACCCAG 
CTCTTCTACT GCCGCAAGCT GCGCTACCTG GACCTCAGCC ACAACAACCT GACCTTGCTC 
CCCGCTGACA TTGGCCTCTT GCAGAACCTC CAGAACCTGG CCGTCACAGC CAATAGGATC 
GAGGCGCTCC CCCCGGAGCT CTTCCAGTGT CGGAAGCTGC GGGCTCTACA CCTGGGCAAC 
AATGTTCTGC AGTCACTGCC CTCGAGAGTG GGTGAGCTGA CCAACCTGAC GCAGATTGAG 
CTTCGGGGCA ACCGGCTGGA GTGCCTGCCC GTGGAGCTGG GCGAGTGTCC CCTGCTCAAG 
CGCAGCGGCC TGGTGGTAGA GGAGGACTTG TTCAGCACAC TGCCGCCTGA GGTGAAGGAA 
CGGCTCTGGA GAGCTGACAA GGAGCAGGCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lrrc8a ( XM_017591840.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017447329.1 Rattus norvegicus leucine rich repeat containing 8 family, member A (Lrrc8a), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa06648
Clone ID Related Accession (Same CDS sequence)	XM_017591843.1 , NM_001024782.1 , XM_017591840.1 , XM_017591842.1 , XM_017591841.1
Accession Version	XM_017591840.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2433bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	volume-regulated anion channel subunit LRRC8A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATTCCGG TGACAGAGCT CCGCTACTTC GCGGACACGC AGCCAGCATA CCGGATCCTG 
AAGCCGTGGT GGGATGTGTT CACTGACTAC ATCTCCATTG TCATGCTGAT GATTGCTGTC 
TTTGGGGGGA CACTGCAAGT CACCCAGGAC AAGATGATCT GCCTACCTTG TAAGTGGGTC 
ACCAAAGACT CCTGCAACGA CTCCTTCCGG GGCTGGGGGG CCTCCAGCCC AGAGCCCACT 
TACCCCAACT CCACAGTCCT GCCTACTCCT GACACGGGCC CCACAGGTAT CAAGTATGAC 
CTAGATCGCC ACCAGTACAA CTACGTGGAT GCCGTGTGTT ACGAGAACCG CCTGCATTGG 
TTTGCCAAGT ACTTCCCCTA CCTCGTGCTC CTGCACACCC TCATCTTCCT GGCCTGCAGC 
AACTTCTGGT TCAAGTTCCC ACGCACCAGC TCGAAGCTGG AGCACTTCGT GTCTATCCTG 
CTCAAGTGCT TTGATTCGCC ATGGACCACA CGGGCCCTGT CAGAGACAGT AGTGGAGGAG 
AGTGACCCCA AGCCAGCCTT CAGCAAGATG AATGGCTCCA TGGACAAGAA GTCATCCACG 
GTCAGTGAGG ATGTGGAGGC CACTGTGCCC ATGCTGCAGC GGACCAAGTC ACGGATTGAG 
CAGGGCATCG TGGACCGCTC CGAGACAGGT GTGCTGGACA AGAAGGAAGG GGAGCAGGCG 
AAGGCACTGT TTGAGAAGGT GAAGAAGTTC CGGACCCATG TGGAGGAGGG GGACATCGTG 
TACCGCCTCT ACATGCGGCA GACCATCATC AAGGTGATCA AGTTCTTCCT CATCATCTGC 
TACACCGTGT ACTATGTGCA CAACATCAAG TTTGACGTGG ACTGCACCGT GGACATCGAG 
AGCCTGACAG GCTACCGCAC CTACCGCTGT GCCCACCCTC TGGCCACCCT CTTCAAGATC 
CTGGCATCCT TCTACATCAG CCTGGTCATC TTCTACGGCC TCATCTGCAT GTACACCCTG 
TGGTGGATGC TCCGGCGCTC CCTCAAGAAG TACTCGTTTG AGTCGATCCG AGAGGAGAGC 
AGCTACAGCG ACATCCCAGA CGTCAAGAAT GACTTCGCCT TCATGTTGCA CCTCATTGAC 
CAGTATGACC CTCTCTACTC AAAGCGCTTC GCCGTCTTCC TGTCTGAGGT GAGTGAGAAC 
AAGCTGCGTC AGCTGAACCT CAACAACGAG TGGACGCTGG ACAAGCTGCG CCAGCGGCTC 
ACCAAAAACG CCCAGGACAA GCTGGAGCTG CACCTCTTCA TGCTGAGCGG CATCCCGGAC 
ACCGTGTTTG ACCTGCTGGA GTTAGAGGTC CTGAAGCTGG AACTGATCCC CGACGTGACC 
ATCCCGCCCA GCATCGCCCA GCTCACAGGC CTCAAGGAGC TCTGGCTGTA CCACACGGCA 
GCCAAGATCG AGGCTCCCGC CCTGGCCTTC CTGCGAGAGA ACCTGCGGGC GCTGCACATC 
AAGTTCACTG ACATCAAGGA GATCCCACTG TGGATCTACA GCCTGAAGAC ACTGGAGGAG 
CTGCACTTGA CAGGCAACCT GAGCGCAGAG AACAACCGCT ACATCGTCAT TGACGGACTG 
CGGGAGCTCA AACGCCTTAA GGTGCTGCGG CTCAAAAGCA ACCTGAGCAA GCTGCCGCAG 
GTGGTCACGG ACGTGGGCGT GCACCTGCAG AAGCTGTCCA TCAACAATGA GGGCACCAAG 
CTCATCGTCC TCAACAGCCT CAAGAAGATG GTTAACCTGA CAGAGCTGGA GCTGATCCGC 
TGCGACCTGG AGCGTATCCC TCACTCCATC TTTAGCCTCC ACAACCTGCA GGAGATCGAC 
CTGAAGGACA ACAACCTCAA GACCATCGAG GAGATCATCA GCTTCCAGCA TCTGCACCGC 
CTCACCTGCC TTAAGCTGTG GTACAACCAC ATCGCCTACA TCCCCATCCA GATCGGCAAC 
CTCACCAACC TTGAGCGCCT CTACCTGAAC CGCAACAAAA TCGAGAAAAT TCCCACCCAG 
CTCTTCTACT GCCGCAAGCT GCGCTACCTG GACCTCAGCC ACAACAACCT GACCTTGCTC 
CCCGCTGACA TTGGCCTCTT GCAGAACCTC CAGAACCTGG CCGTCACAGC CAATAGGATC 
GAGGCGCTCC CCCCGGAGCT CTTCCAGTGT CGGAAGCTGC GGGCTCTACA CCTGGGCAAC 
AATGTTCTGC AGTCACTGCC CTCGAGAGTG GGTGAGCTGA CCAACCTGAC GCAGATTGAG 
CTTCGGGGCA ACCGGCTGGA GTGCCTGCCC GTGGAGCTGG GCGAGTGTCC CCTGCTCAAG 
CGCAGCGGCC TGGTGGTAGA GGAGGACTTG TTCAGCACAC TGCCGCCTGA GGTGAAGGAA 
CGGCTCTGGA GAGCTGACAA GGAGCAGGCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017447329.1
CDS	946..3378
Translation	MIPVTELRYFADTQPAYRILKPWWDVFTDYISIVMLMIAVFGGTLQVTQDKMICLPCKWVTKDSCNDSFRGWGASSPEPTYPNSTVLPTPDTGPTGIKYDLDRHQYNYVDAVCYENRLHWFAKYFPYLVLLHTLIFLACSNFWFKFPRTSSKLEHFVSILLKCFDSPWTTRALSETVVEESDPKPAFSKMNGSMDKKSSTVSEDVEATVPMLQRTKSRIEQGIVDRSETGVLDKKEGEQAKALFEKVKKFRTHVEEGDIVYRLYMRQTIIKVIKFFLIICYTVYYVHNIKFDVDCTVDIESLTGYRTYRCAHPLATLFKILASFYISLVIFYGLICMYTLWWMLRRSLKKYSFESIREESSYSDIPDVKNDFAFMLHLIDQYDPLYSKRFAVFLSEVSENKLRQLNLNNEWTLDKLRQRLTKNAQDKLELHLFMLSGIPDTVFDLLELEVLKLELIPDVTIPPSIAQLTGLKELWLYHTAAKIEAPALAFLRENLRALHIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGLRELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMVNLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTLLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLKRSGLVVEEDLFSTLPPEVKERLWRADKEQA

Target ORF information:

RefSeq Version	XM_017591840.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus leucine rich repeat containing 8 family, member A (Lrrc8a), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017591840.1

ORF Insert Sequence:

ATGATTCCGG TGACAGAGCT CCGCTACTTC GCGGACACGC AGCCAGCATA CCGGATCCTG 
AAGCCGTGGT GGGATGTGTT CACTGACTAC ATCTCCATTG TCATGCTGAT GATTGCTGTC 
TTTGGGGGGA CACTGCAAGT CACCCAGGAC AAGATGATCT GCCTACCTTG TAAGTGGGTC 
ACCAAAGACT CCTGCAACGA CTCCTTCCGG GGCTGGGGGG CCTCCAGCCC AGAGCCCACT 
TACCCCAACT CCACAGTCCT GCCTACTCCT GACACGGGCC CCACAGGTAT CAAGTATGAC 
CTAGATCGCC ACCAGTACAA CTACGTGGAT GCCGTGTGTT ACGAGAACCG CCTGCATTGG 
TTTGCCAAGT ACTTCCCCTA CCTCGTGCTC CTGCACACCC TCATCTTCCT GGCCTGCAGC 
AACTTCTGGT TCAAGTTCCC ACGCACCAGC TCGAAGCTGG AGCACTTCGT GTCTATCCTG 
CTCAAGTGCT TTGATTCGCC ATGGACCACA CGGGCCCTGT CAGAGACAGT AGTGGAGGAG 
AGTGACCCCA AGCCAGCCTT CAGCAAGATG AATGGCTCCA TGGACAAGAA GTCATCCACG 
GTCAGTGAGG ATGTGGAGGC CACTGTGCCC ATGCTGCAGC GGACCAAGTC ACGGATTGAG 
CAGGGCATCG TGGACCGCTC CGAGACAGGT GTGCTGGACA AGAAGGAAGG GGAGCAGGCG 
AAGGCACTGT TTGAGAAGGT GAAGAAGTTC CGGACCCATG TGGAGGAGGG GGACATCGTG 
TACCGCCTCT ACATGCGGCA GACCATCATC AAGGTGATCA AGTTCTTCCT CATCATCTGC 
TACACCGTGT ACTATGTGCA CAACATCAAG TTTGACGTGG ACTGCACCGT GGACATCGAG 
AGCCTGACAG GCTACCGCAC CTACCGCTGT GCCCACCCTC TGGCCACCCT CTTCAAGATC 
CTGGCATCCT TCTACATCAG CCTGGTCATC TTCTACGGCC TCATCTGCAT GTACACCCTG 
TGGTGGATGC TCCGGCGCTC CCTCAAGAAG TACTCGTTTG AGTCGATCCG AGAGGAGAGC 
AGCTACAGCG ACATCCCAGA CGTCAAGAAT GACTTCGCCT TCATGTTGCA CCTCATTGAC 
CAGTATGACC CTCTCTACTC AAAGCGCTTC GCCGTCTTCC TGTCTGAGGT GAGTGAGAAC 
AAGCTGCGTC AGCTGAACCT CAACAACGAG TGGACGCTGG ACAAGCTGCG CCAGCGGCTC 
ACCAAAAACG CCCAGGACAA GCTGGAGCTG CACCTCTTCA TGCTGAGCGG CATCCCGGAC 
ACCGTGTTTG ACCTGCTGGA GTTAGAGGTC CTGAAGCTGG AACTGATCCC CGACGTGACC 
ATCCCGCCCA GCATCGCCCA GCTCACAGGC CTCAAGGAGC TCTGGCTGTA CCACACGGCA 
GCCAAGATCG AGGCTCCCGC CCTGGCCTTC CTGCGAGAGA ACCTGCGGGC GCTGCACATC 
AAGTTCACTG ACATCAAGGA GATCCCACTG TGGATCTACA GCCTGAAGAC ACTGGAGGAG 
CTGCACTTGA CAGGCAACCT GAGCGCAGAG AACAACCGCT ACATCGTCAT TGACGGACTG 
CGGGAGCTCA AACGCCTTAA GGTGCTGCGG CTCAAAAGCA ACCTGAGCAA GCTGCCGCAG 
GTGGTCACGG ACGTGGGCGT GCACCTGCAG AAGCTGTCCA TCAACAATGA GGGCACCAAG 
CTCATCGTCC TCAACAGCCT CAAGAAGATG GTTAACCTGA CAGAGCTGGA GCTGATCCGC 
TGCGACCTGG AGCGTATCCC TCACTCCATC TTTAGCCTCC ACAACCTGCA GGAGATCGAC 
CTGAAGGACA ACAACCTCAA GACCATCGAG GAGATCATCA GCTTCCAGCA TCTGCACCGC 
CTCACCTGCC TTAAGCTGTG GTACAACCAC ATCGCCTACA TCCCCATCCA GATCGGCAAC 
CTCACCAACC TTGAGCGCCT CTACCTGAAC CGCAACAAAA TCGAGAAAAT TCCCACCCAG 
CTCTTCTACT GCCGCAAGCT GCGCTACCTG GACCTCAGCC ACAACAACCT GACCTTGCTC 
CCCGCTGACA TTGGCCTCTT GCAGAACCTC CAGAACCTGG CCGTCACAGC CAATAGGATC 
GAGGCGCTCC CCCCGGAGCT CTTCCAGTGT CGGAAGCTGC GGGCTCTACA CCTGGGCAAC 
AATGTTCTGC AGTCACTGCC CTCGAGAGTG GGTGAGCTGA CCAACCTGAC GCAGATTGAG 
CTTCGGGGCA ACCGGCTGGA GTGCCTGCCC GTGGAGCTGG GCGAGTGTCC CCTGCTCAAG 
CGCAGCGGCC TGGTGGTAGA GGAGGACTTG TTCAGCACAC TGCCGCCTGA GGTGAAGGAA 
CGGCTCTGGA GAGCTGACAA GGAGCAGGCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lrrc8a ( XM_017591842.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017447331.1 Rattus norvegicus leucine rich repeat containing 8 family, member A (Lrrc8a), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa06648
Clone ID Related Accession (Same CDS sequence)	XM_017591843.1 , NM_001024782.1 , XM_017591840.1 , XM_017591842.1 , XM_017591841.1
Accession Version	XM_017591842.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2433bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	volume-regulated anion channel subunit LRRC8A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATTCCGG TGACAGAGCT CCGCTACTTC GCGGACACGC AGCCAGCATA CCGGATCCTG 
AAGCCGTGGT GGGATGTGTT CACTGACTAC ATCTCCATTG TCATGCTGAT GATTGCTGTC 
TTTGGGGGGA CACTGCAAGT CACCCAGGAC AAGATGATCT GCCTACCTTG TAAGTGGGTC 
ACCAAAGACT CCTGCAACGA CTCCTTCCGG GGCTGGGGGG CCTCCAGCCC AGAGCCCACT 
TACCCCAACT CCACAGTCCT GCCTACTCCT GACACGGGCC CCACAGGTAT CAAGTATGAC 
CTAGATCGCC ACCAGTACAA CTACGTGGAT GCCGTGTGTT ACGAGAACCG CCTGCATTGG 
TTTGCCAAGT ACTTCCCCTA CCTCGTGCTC CTGCACACCC TCATCTTCCT GGCCTGCAGC 
AACTTCTGGT TCAAGTTCCC ACGCACCAGC TCGAAGCTGG AGCACTTCGT GTCTATCCTG 
CTCAAGTGCT TTGATTCGCC ATGGACCACA CGGGCCCTGT CAGAGACAGT AGTGGAGGAG 
AGTGACCCCA AGCCAGCCTT CAGCAAGATG AATGGCTCCA TGGACAAGAA GTCATCCACG 
GTCAGTGAGG ATGTGGAGGC CACTGTGCCC ATGCTGCAGC GGACCAAGTC ACGGATTGAG 
CAGGGCATCG TGGACCGCTC CGAGACAGGT GTGCTGGACA AGAAGGAAGG GGAGCAGGCG 
AAGGCACTGT TTGAGAAGGT GAAGAAGTTC CGGACCCATG TGGAGGAGGG GGACATCGTG 
TACCGCCTCT ACATGCGGCA GACCATCATC AAGGTGATCA AGTTCTTCCT CATCATCTGC 
TACACCGTGT ACTATGTGCA CAACATCAAG TTTGACGTGG ACTGCACCGT GGACATCGAG 
AGCCTGACAG GCTACCGCAC CTACCGCTGT GCCCACCCTC TGGCCACCCT CTTCAAGATC 
CTGGCATCCT TCTACATCAG CCTGGTCATC TTCTACGGCC TCATCTGCAT GTACACCCTG 
TGGTGGATGC TCCGGCGCTC CCTCAAGAAG TACTCGTTTG AGTCGATCCG AGAGGAGAGC 
AGCTACAGCG ACATCCCAGA CGTCAAGAAT GACTTCGCCT TCATGTTGCA CCTCATTGAC 
CAGTATGACC CTCTCTACTC AAAGCGCTTC GCCGTCTTCC TGTCTGAGGT GAGTGAGAAC 
AAGCTGCGTC AGCTGAACCT CAACAACGAG TGGACGCTGG ACAAGCTGCG CCAGCGGCTC 
ACCAAAAACG CCCAGGACAA GCTGGAGCTG CACCTCTTCA TGCTGAGCGG CATCCCGGAC 
ACCGTGTTTG ACCTGCTGGA GTTAGAGGTC CTGAAGCTGG AACTGATCCC CGACGTGACC 
ATCCCGCCCA GCATCGCCCA GCTCACAGGC CTCAAGGAGC TCTGGCTGTA CCACACGGCA 
GCCAAGATCG AGGCTCCCGC CCTGGCCTTC CTGCGAGAGA ACCTGCGGGC GCTGCACATC 
AAGTTCACTG ACATCAAGGA GATCCCACTG TGGATCTACA GCCTGAAGAC ACTGGAGGAG 
CTGCACTTGA CAGGCAACCT GAGCGCAGAG AACAACCGCT ACATCGTCAT TGACGGACTG 
CGGGAGCTCA AACGCCTTAA GGTGCTGCGG CTCAAAAGCA ACCTGAGCAA GCTGCCGCAG 
GTGGTCACGG ACGTGGGCGT GCACCTGCAG AAGCTGTCCA TCAACAATGA GGGCACCAAG 
CTCATCGTCC TCAACAGCCT CAAGAAGATG GTTAACCTGA CAGAGCTGGA GCTGATCCGC 
TGCGACCTGG AGCGTATCCC TCACTCCATC TTTAGCCTCC ACAACCTGCA GGAGATCGAC 
CTGAAGGACA ACAACCTCAA GACCATCGAG GAGATCATCA GCTTCCAGCA TCTGCACCGC 
CTCACCTGCC TTAAGCTGTG GTACAACCAC ATCGCCTACA TCCCCATCCA GATCGGCAAC 
CTCACCAACC TTGAGCGCCT CTACCTGAAC CGCAACAAAA TCGAGAAAAT TCCCACCCAG 
CTCTTCTACT GCCGCAAGCT GCGCTACCTG GACCTCAGCC ACAACAACCT GACCTTGCTC 
CCCGCTGACA TTGGCCTCTT GCAGAACCTC CAGAACCTGG CCGTCACAGC CAATAGGATC 
GAGGCGCTCC CCCCGGAGCT CTTCCAGTGT CGGAAGCTGC GGGCTCTACA CCTGGGCAAC 
AATGTTCTGC AGTCACTGCC CTCGAGAGTG GGTGAGCTGA CCAACCTGAC GCAGATTGAG 
CTTCGGGGCA ACCGGCTGGA GTGCCTGCCC GTGGAGCTGG GCGAGTGTCC CCTGCTCAAG 
CGCAGCGGCC TGGTGGTAGA GGAGGACTTG TTCAGCACAC TGCCGCCTGA GGTGAAGGAA 
CGGCTCTGGA GAGCTGACAA GGAGCAGGCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017447331.1
CDS	1097..3529
Translation	MIPVTELRYFADTQPAYRILKPWWDVFTDYISIVMLMIAVFGGTLQVTQDKMICLPCKWVTKDSCNDSFRGWGASSPEPTYPNSTVLPTPDTGPTGIKYDLDRHQYNYVDAVCYENRLHWFAKYFPYLVLLHTLIFLACSNFWFKFPRTSSKLEHFVSILLKCFDSPWTTRALSETVVEESDPKPAFSKMNGSMDKKSSTVSEDVEATVPMLQRTKSRIEQGIVDRSETGVLDKKEGEQAKALFEKVKKFRTHVEEGDIVYRLYMRQTIIKVIKFFLIICYTVYYVHNIKFDVDCTVDIESLTGYRTYRCAHPLATLFKILASFYISLVIFYGLICMYTLWWMLRRSLKKYSFESIREESSYSDIPDVKNDFAFMLHLIDQYDPLYSKRFAVFLSEVSENKLRQLNLNNEWTLDKLRQRLTKNAQDKLELHLFMLSGIPDTVFDLLELEVLKLELIPDVTIPPSIAQLTGLKELWLYHTAAKIEAPALAFLRENLRALHIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGLRELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMVNLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTLLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLKRSGLVVEEDLFSTLPPEVKERLWRADKEQA

Target ORF information:

RefSeq Version	XM_017591842.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus leucine rich repeat containing 8 family, member A (Lrrc8a), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017591842.1

ORF Insert Sequence:

ATGATTCCGG TGACAGAGCT CCGCTACTTC GCGGACACGC AGCCAGCATA CCGGATCCTG 
AAGCCGTGGT GGGATGTGTT CACTGACTAC ATCTCCATTG TCATGCTGAT GATTGCTGTC 
TTTGGGGGGA CACTGCAAGT CACCCAGGAC AAGATGATCT GCCTACCTTG TAAGTGGGTC 
ACCAAAGACT CCTGCAACGA CTCCTTCCGG GGCTGGGGGG CCTCCAGCCC AGAGCCCACT 
TACCCCAACT CCACAGTCCT GCCTACTCCT GACACGGGCC CCACAGGTAT CAAGTATGAC 
CTAGATCGCC ACCAGTACAA CTACGTGGAT GCCGTGTGTT ACGAGAACCG CCTGCATTGG 
TTTGCCAAGT ACTTCCCCTA CCTCGTGCTC CTGCACACCC TCATCTTCCT GGCCTGCAGC 
AACTTCTGGT TCAAGTTCCC ACGCACCAGC TCGAAGCTGG AGCACTTCGT GTCTATCCTG 
CTCAAGTGCT TTGATTCGCC ATGGACCACA CGGGCCCTGT CAGAGACAGT AGTGGAGGAG 
AGTGACCCCA AGCCAGCCTT CAGCAAGATG AATGGCTCCA TGGACAAGAA GTCATCCACG 
GTCAGTGAGG ATGTGGAGGC CACTGTGCCC ATGCTGCAGC GGACCAAGTC ACGGATTGAG 
CAGGGCATCG TGGACCGCTC CGAGACAGGT GTGCTGGACA AGAAGGAAGG GGAGCAGGCG 
AAGGCACTGT TTGAGAAGGT GAAGAAGTTC CGGACCCATG TGGAGGAGGG GGACATCGTG 
TACCGCCTCT ACATGCGGCA GACCATCATC AAGGTGATCA AGTTCTTCCT CATCATCTGC 
TACACCGTGT ACTATGTGCA CAACATCAAG TTTGACGTGG ACTGCACCGT GGACATCGAG 
AGCCTGACAG GCTACCGCAC CTACCGCTGT GCCCACCCTC TGGCCACCCT CTTCAAGATC 
CTGGCATCCT TCTACATCAG CCTGGTCATC TTCTACGGCC TCATCTGCAT GTACACCCTG 
TGGTGGATGC TCCGGCGCTC CCTCAAGAAG TACTCGTTTG AGTCGATCCG AGAGGAGAGC 
AGCTACAGCG ACATCCCAGA CGTCAAGAAT GACTTCGCCT TCATGTTGCA CCTCATTGAC 
CAGTATGACC CTCTCTACTC AAAGCGCTTC GCCGTCTTCC TGTCTGAGGT GAGTGAGAAC 
AAGCTGCGTC AGCTGAACCT CAACAACGAG TGGACGCTGG ACAAGCTGCG CCAGCGGCTC 
ACCAAAAACG CCCAGGACAA GCTGGAGCTG CACCTCTTCA TGCTGAGCGG CATCCCGGAC 
ACCGTGTTTG ACCTGCTGGA GTTAGAGGTC CTGAAGCTGG AACTGATCCC CGACGTGACC 
ATCCCGCCCA GCATCGCCCA GCTCACAGGC CTCAAGGAGC TCTGGCTGTA CCACACGGCA 
GCCAAGATCG AGGCTCCCGC CCTGGCCTTC CTGCGAGAGA ACCTGCGGGC GCTGCACATC 
AAGTTCACTG ACATCAAGGA GATCCCACTG TGGATCTACA GCCTGAAGAC ACTGGAGGAG 
CTGCACTTGA CAGGCAACCT GAGCGCAGAG AACAACCGCT ACATCGTCAT TGACGGACTG 
CGGGAGCTCA AACGCCTTAA GGTGCTGCGG CTCAAAAGCA ACCTGAGCAA GCTGCCGCAG 
GTGGTCACGG ACGTGGGCGT GCACCTGCAG AAGCTGTCCA TCAACAATGA GGGCACCAAG 
CTCATCGTCC TCAACAGCCT CAAGAAGATG GTTAACCTGA CAGAGCTGGA GCTGATCCGC 
TGCGACCTGG AGCGTATCCC TCACTCCATC TTTAGCCTCC ACAACCTGCA GGAGATCGAC 
CTGAAGGACA ACAACCTCAA GACCATCGAG GAGATCATCA GCTTCCAGCA TCTGCACCGC 
CTCACCTGCC TTAAGCTGTG GTACAACCAC ATCGCCTACA TCCCCATCCA GATCGGCAAC 
CTCACCAACC TTGAGCGCCT CTACCTGAAC CGCAACAAAA TCGAGAAAAT TCCCACCCAG 
CTCTTCTACT GCCGCAAGCT GCGCTACCTG GACCTCAGCC ACAACAACCT GACCTTGCTC 
CCCGCTGACA TTGGCCTCTT GCAGAACCTC CAGAACCTGG CCGTCACAGC CAATAGGATC 
GAGGCGCTCC CCCCGGAGCT CTTCCAGTGT CGGAAGCTGC GGGCTCTACA CCTGGGCAAC 
AATGTTCTGC AGTCACTGCC CTCGAGAGTG GGTGAGCTGA CCAACCTGAC GCAGATTGAG 
CTTCGGGGCA ACCGGCTGGA GTGCCTGCCC GTGGAGCTGG GCGAGTGTCC CCTGCTCAAG 
CGCAGCGGCC TGGTGGTAGA GGAGGACTTG TTCAGCACAC TGCCGCCTGA GGTGAAGGAA 
CGGCTCTGGA GAGCTGACAA GGAGCAGGCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lrrc8a ( XM_017591841.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017447330.1 Rattus norvegicus leucine rich repeat containing 8 family, member A (Lrrc8a), transcript variant X2, mRNA.

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CloneID	ORa06648
Clone ID Related Accession (Same CDS sequence)	XM_017591843.1 , NM_001024782.1 , XM_017591840.1 , XM_017591842.1 , XM_017591841.1
Accession Version	XM_017591841.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2433bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	volume-regulated anion channel subunit LRRC8A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATTCCGG TGACAGAGCT CCGCTACTTC GCGGACACGC AGCCAGCATA CCGGATCCTG 
AAGCCGTGGT GGGATGTGTT CACTGACTAC ATCTCCATTG TCATGCTGAT GATTGCTGTC 
TTTGGGGGGA CACTGCAAGT CACCCAGGAC AAGATGATCT GCCTACCTTG TAAGTGGGTC 
ACCAAAGACT CCTGCAACGA CTCCTTCCGG GGCTGGGGGG CCTCCAGCCC AGAGCCCACT 
TACCCCAACT CCACAGTCCT GCCTACTCCT GACACGGGCC CCACAGGTAT CAAGTATGAC 
CTAGATCGCC ACCAGTACAA CTACGTGGAT GCCGTGTGTT ACGAGAACCG CCTGCATTGG 
TTTGCCAAGT ACTTCCCCTA CCTCGTGCTC CTGCACACCC TCATCTTCCT GGCCTGCAGC 
AACTTCTGGT TCAAGTTCCC ACGCACCAGC TCGAAGCTGG AGCACTTCGT GTCTATCCTG 
CTCAAGTGCT TTGATTCGCC ATGGACCACA CGGGCCCTGT CAGAGACAGT AGTGGAGGAG 
AGTGACCCCA AGCCAGCCTT CAGCAAGATG AATGGCTCCA TGGACAAGAA GTCATCCACG 
GTCAGTGAGG ATGTGGAGGC CACTGTGCCC ATGCTGCAGC GGACCAAGTC ACGGATTGAG 
CAGGGCATCG TGGACCGCTC CGAGACAGGT GTGCTGGACA AGAAGGAAGG GGAGCAGGCG 
AAGGCACTGT TTGAGAAGGT GAAGAAGTTC CGGACCCATG TGGAGGAGGG GGACATCGTG 
TACCGCCTCT ACATGCGGCA GACCATCATC AAGGTGATCA AGTTCTTCCT CATCATCTGC 
TACACCGTGT ACTATGTGCA CAACATCAAG TTTGACGTGG ACTGCACCGT GGACATCGAG 
AGCCTGACAG GCTACCGCAC CTACCGCTGT GCCCACCCTC TGGCCACCCT CTTCAAGATC 
CTGGCATCCT TCTACATCAG CCTGGTCATC TTCTACGGCC TCATCTGCAT GTACACCCTG 
TGGTGGATGC TCCGGCGCTC CCTCAAGAAG TACTCGTTTG AGTCGATCCG AGAGGAGAGC 
AGCTACAGCG ACATCCCAGA CGTCAAGAAT GACTTCGCCT TCATGTTGCA CCTCATTGAC 
CAGTATGACC CTCTCTACTC AAAGCGCTTC GCCGTCTTCC TGTCTGAGGT GAGTGAGAAC 
AAGCTGCGTC AGCTGAACCT CAACAACGAG TGGACGCTGG ACAAGCTGCG CCAGCGGCTC 
ACCAAAAACG CCCAGGACAA GCTGGAGCTG CACCTCTTCA TGCTGAGCGG CATCCCGGAC 
ACCGTGTTTG ACCTGCTGGA GTTAGAGGTC CTGAAGCTGG AACTGATCCC CGACGTGACC 
ATCCCGCCCA GCATCGCCCA GCTCACAGGC CTCAAGGAGC TCTGGCTGTA CCACACGGCA 
GCCAAGATCG AGGCTCCCGC CCTGGCCTTC CTGCGAGAGA ACCTGCGGGC GCTGCACATC 
AAGTTCACTG ACATCAAGGA GATCCCACTG TGGATCTACA GCCTGAAGAC ACTGGAGGAG 
CTGCACTTGA CAGGCAACCT GAGCGCAGAG AACAACCGCT ACATCGTCAT TGACGGACTG 
CGGGAGCTCA AACGCCTTAA GGTGCTGCGG CTCAAAAGCA ACCTGAGCAA GCTGCCGCAG 
GTGGTCACGG ACGTGGGCGT GCACCTGCAG AAGCTGTCCA TCAACAATGA GGGCACCAAG 
CTCATCGTCC TCAACAGCCT CAAGAAGATG GTTAACCTGA CAGAGCTGGA GCTGATCCGC 
TGCGACCTGG AGCGTATCCC TCACTCCATC TTTAGCCTCC ACAACCTGCA GGAGATCGAC 
CTGAAGGACA ACAACCTCAA GACCATCGAG GAGATCATCA GCTTCCAGCA TCTGCACCGC 
CTCACCTGCC TTAAGCTGTG GTACAACCAC ATCGCCTACA TCCCCATCCA GATCGGCAAC 
CTCACCAACC TTGAGCGCCT CTACCTGAAC CGCAACAAAA TCGAGAAAAT TCCCACCCAG 
CTCTTCTACT GCCGCAAGCT GCGCTACCTG GACCTCAGCC ACAACAACCT GACCTTGCTC 
CCCGCTGACA TTGGCCTCTT GCAGAACCTC CAGAACCTGG CCGTCACAGC CAATAGGATC 
GAGGCGCTCC CCCCGGAGCT CTTCCAGTGT CGGAAGCTGC GGGCTCTACA CCTGGGCAAC 
AATGTTCTGC AGTCACTGCC CTCGAGAGTG GGTGAGCTGA CCAACCTGAC GCAGATTGAG 
CTTCGGGGCA ACCGGCTGGA GTGCCTGCCC GTGGAGCTGG GCGAGTGTCC CCTGCTCAAG 
CGCAGCGGCC TGGTGGTAGA GGAGGACTTG TTCAGCACAC TGCCGCCTGA GGTGAAGGAA 
CGGCTCTGGA GAGCTGACAA GGAGCAGGCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017447330.1
CDS	572..3004
Translation	MIPVTELRYFADTQPAYRILKPWWDVFTDYISIVMLMIAVFGGTLQVTQDKMICLPCKWVTKDSCNDSFRGWGASSPEPTYPNSTVLPTPDTGPTGIKYDLDRHQYNYVDAVCYENRLHWFAKYFPYLVLLHTLIFLACSNFWFKFPRTSSKLEHFVSILLKCFDSPWTTRALSETVVEESDPKPAFSKMNGSMDKKSSTVSEDVEATVPMLQRTKSRIEQGIVDRSETGVLDKKEGEQAKALFEKVKKFRTHVEEGDIVYRLYMRQTIIKVIKFFLIICYTVYYVHNIKFDVDCTVDIESLTGYRTYRCAHPLATLFKILASFYISLVIFYGLICMYTLWWMLRRSLKKYSFESIREESSYSDIPDVKNDFAFMLHLIDQYDPLYSKRFAVFLSEVSENKLRQLNLNNEWTLDKLRQRLTKNAQDKLELHLFMLSGIPDTVFDLLELEVLKLELIPDVTIPPSIAQLTGLKELWLYHTAAKIEAPALAFLRENLRALHIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGLRELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMVNLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTLLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLKRSGLVVEEDLFSTLPPEVKERLWRADKEQA

Target ORF information:

RefSeq Version	XM_017591841.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus leucine rich repeat containing 8 family, member A (Lrrc8a), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017591841.1

ORF Insert Sequence:

ATGATTCCGG TGACAGAGCT CCGCTACTTC GCGGACACGC AGCCAGCATA CCGGATCCTG 
AAGCCGTGGT GGGATGTGTT CACTGACTAC ATCTCCATTG TCATGCTGAT GATTGCTGTC 
TTTGGGGGGA CACTGCAAGT CACCCAGGAC AAGATGATCT GCCTACCTTG TAAGTGGGTC 
ACCAAAGACT CCTGCAACGA CTCCTTCCGG GGCTGGGGGG CCTCCAGCCC AGAGCCCACT 
TACCCCAACT CCACAGTCCT GCCTACTCCT GACACGGGCC CCACAGGTAT CAAGTATGAC 
CTAGATCGCC ACCAGTACAA CTACGTGGAT GCCGTGTGTT ACGAGAACCG CCTGCATTGG 
TTTGCCAAGT ACTTCCCCTA CCTCGTGCTC CTGCACACCC TCATCTTCCT GGCCTGCAGC 
AACTTCTGGT TCAAGTTCCC ACGCACCAGC TCGAAGCTGG AGCACTTCGT GTCTATCCTG 
CTCAAGTGCT TTGATTCGCC ATGGACCACA CGGGCCCTGT CAGAGACAGT AGTGGAGGAG 
AGTGACCCCA AGCCAGCCTT CAGCAAGATG AATGGCTCCA TGGACAAGAA GTCATCCACG 
GTCAGTGAGG ATGTGGAGGC CACTGTGCCC ATGCTGCAGC GGACCAAGTC ACGGATTGAG 
CAGGGCATCG TGGACCGCTC CGAGACAGGT GTGCTGGACA AGAAGGAAGG GGAGCAGGCG 
AAGGCACTGT TTGAGAAGGT GAAGAAGTTC CGGACCCATG TGGAGGAGGG GGACATCGTG 
TACCGCCTCT ACATGCGGCA GACCATCATC AAGGTGATCA AGTTCTTCCT CATCATCTGC 
TACACCGTGT ACTATGTGCA CAACATCAAG TTTGACGTGG ACTGCACCGT GGACATCGAG 
AGCCTGACAG GCTACCGCAC CTACCGCTGT GCCCACCCTC TGGCCACCCT CTTCAAGATC 
CTGGCATCCT TCTACATCAG CCTGGTCATC TTCTACGGCC TCATCTGCAT GTACACCCTG 
TGGTGGATGC TCCGGCGCTC CCTCAAGAAG TACTCGTTTG AGTCGATCCG AGAGGAGAGC 
AGCTACAGCG ACATCCCAGA CGTCAAGAAT GACTTCGCCT TCATGTTGCA CCTCATTGAC 
CAGTATGACC CTCTCTACTC AAAGCGCTTC GCCGTCTTCC TGTCTGAGGT GAGTGAGAAC 
AAGCTGCGTC AGCTGAACCT CAACAACGAG TGGACGCTGG ACAAGCTGCG CCAGCGGCTC 
ACCAAAAACG CCCAGGACAA GCTGGAGCTG CACCTCTTCA TGCTGAGCGG CATCCCGGAC 
ACCGTGTTTG ACCTGCTGGA GTTAGAGGTC CTGAAGCTGG AACTGATCCC CGACGTGACC 
ATCCCGCCCA GCATCGCCCA GCTCACAGGC CTCAAGGAGC TCTGGCTGTA CCACACGGCA 
GCCAAGATCG AGGCTCCCGC CCTGGCCTTC CTGCGAGAGA ACCTGCGGGC GCTGCACATC 
AAGTTCACTG ACATCAAGGA GATCCCACTG TGGATCTACA GCCTGAAGAC ACTGGAGGAG 
CTGCACTTGA CAGGCAACCT GAGCGCAGAG AACAACCGCT ACATCGTCAT TGACGGACTG 
CGGGAGCTCA AACGCCTTAA GGTGCTGCGG CTCAAAAGCA ACCTGAGCAA GCTGCCGCAG 
GTGGTCACGG ACGTGGGCGT GCACCTGCAG AAGCTGTCCA TCAACAATGA GGGCACCAAG 
CTCATCGTCC TCAACAGCCT CAAGAAGATG GTTAACCTGA CAGAGCTGGA GCTGATCCGC 
TGCGACCTGG AGCGTATCCC TCACTCCATC TTTAGCCTCC ACAACCTGCA GGAGATCGAC 
CTGAAGGACA ACAACCTCAA GACCATCGAG GAGATCATCA GCTTCCAGCA TCTGCACCGC 
CTCACCTGCC TTAAGCTGTG GTACAACCAC ATCGCCTACA TCCCCATCCA GATCGGCAAC 
CTCACCAACC TTGAGCGCCT CTACCTGAAC CGCAACAAAA TCGAGAAAAT TCCCACCCAG 
CTCTTCTACT GCCGCAAGCT GCGCTACCTG GACCTCAGCC ACAACAACCT GACCTTGCTC 
CCCGCTGACA TTGGCCTCTT GCAGAACCTC CAGAACCTGG CCGTCACAGC CAATAGGATC 
GAGGCGCTCC CCCCGGAGCT CTTCCAGTGT CGGAAGCTGC GGGCTCTACA CCTGGGCAAC 
AATGTTCTGC AGTCACTGCC CTCGAGAGTG GGTGAGCTGA CCAACCTGAC GCAGATTGAG 
CTTCGGGGCA ACCGGCTGGA GTGCCTGCCC GTGGAGCTGG GCGAGTGTCC CCTGCTCAAG 
CGCAGCGGCC TGGTGGTAGA GGAGGACTTG TTCAGCACAC TGCCGCCTGA GGTGAAGGAA 
CGGCTCTGGA GAGCTGACAA GGAGCAGGCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Molecular composition and heterogeneity of the LRRC8-containing swelling-activated osmolyte channels in primary rat astrocytes.
The Journal of physiology595(22)6939-6951(2017 Nov)
Schober AL,Wilson CS,Mongin AA

LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength.
Cell164(3)499-511(2016 Jan)
Syeda R,Qiu Z,Dubin AE,Murthy SE,Florendo MN,Mason DE,Mathur J,Cahalan SM,Peters EC,Montal M,Patapoutian A

Identification of LRRC8 heteromers as an essential component of the volume-regulated anion channel VRAC.
Science (New York, N.Y.)344(6184)634-8(2014 May)
Voss FK,Ullrich F,M?nch J,Lazarow K,Lutter D,Mah N,Andrade-Navarro MA,von Kries JP,Stauber T,Jentsch TJ

SWELL1, a plasma membrane protein, is an essential component of volume-regulated anion channel.
Cell157(2)447-458(2014 Apr)
Qiu Z,Dubin AE,Mathur J,Tu B,Reddy K,Miraglia LJ,Reinhardt J,Orth AP,Patapoutian A

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Lrrc8a cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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