Prex1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Prex1
Entrez Gene ID	311647
Full Name	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
Synonyms	RGD1306534
General protein information	Preferred Names phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 Names phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q42

mRNA and Protein(s)

mRNA	Protein	Name
NM_001135718.1	NP_001129190.1	phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein

Pathways from BioSystems

Homologies

Homo sapiens (human)	PREX1	NP_065871.2
Bos taurus (cattle)	PREX1	XP_002692397.3
Canis lupus familiaris (dog)	PREX1	XP_543041.3
Gallus gallus (chicken)	PREX1	XP_004947127.1
Danio rerio (zebrafish)	prex1	XP_699627.3
Pan troglodytes (chimpanzee)	PREX1	XP_003953812.1
	PREX1	XP_002798174.1
Rattus norvegicus (Norway rat)	Prex1	NP_001129190.1
Mus musculus (house mouse)	Prex1	NP_808450.2
Xenopus tropicalis (tropical clawed frog)	prex1	XP_002933203.1

Gene Ontology
Bibliography

Related articles in PubMed

Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis.
Qin J, Xie Y, Wang B, Hoshino M, Wolff DW, Zhao J, Scofield MA, Dowd FJ, Lin MF, Tu Y
Oncogene28(16)1853-63(2009 Apr)

P-Rex1 - a multidomain protein that regulates neurite differentiation.
Waters JE, Astle MV, Ooms LM, Balamatsias D, Gurung R, Mitchell CA
Journal of cell science121(Pt 17)2892-903(2008 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study has identified P-Rex1 as a Rac3-guanine nucleotide exchange factor in neuronal cells that localises to, and regulates, actin cytoskeletal dynamics at the axonal growth cone to in turn regulate neurite differentiation.
Title: P-Rex1 - a multidomain protein that regulates neurite differentiation.

The following Prex1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Prex1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa34923	NM_001135718.1 Latest version!	Rattus norvegicus phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 (Prex1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$1210.30 $1729.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Prex1 ( NM_001135718.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001129190.1 Rattus norvegicus phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 (Prex1), mRNA.

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CloneID	ORa34923
Clone ID Related Accession (Same CDS sequence)	NM_001135718.1
Accession Version	NM_001135718.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4941bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2011-07-15
Organism	Rattus norvegicus(Norway rat)
Product	phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AABR03026539.1, AABR03024449.1, AABR03025841.1 and AABR03026116.1. On Oct 8, 2008 this sequence version replaced XM_230873.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.

ATGGAGGCGC CCGGCAGCGG TAGTGGCGAT GGCGGCGGGG ACCCAGGCGG GGACGGTGCG 
CATCCCGATG CTCGCGGTCC CAGCTCCGGG CCATGCGCGG CCGCCCGCGA CTCGGAGCGC 
CAGCTGCGCC TCCGTCTGTG CGTACTCAAC GAGATCCTGG CCACCGAGCG CGACTACGTG 
GGCACCTTGC GTTTCCTGCA GTCGGCGTTC CTACAGCGGA TCCGGCAGAA TGTGGCCGAC 
TCTGTGGACA AGGGCCTCAC GGAAGAGAAT GTCAAGATCC TCTTCTCCAA CATTGAGGAC 
ATCTTGGAGG TCCATAAGGA TTTTTTGGCT GCCCTGGAAT ACTGCCTACA TCCGGAGCCC 
CAGTCTCAGC ACGAACTTGG GAATGTTTTC TTGAAATTTA AGGACAAGTT CTGTGTGTAT 
GAGGAGTACT GCAGTAACCA CGAGAAGGCC CTGCGTCTGT TGGTGGAGCT CAACAAGGTC 
CCTGCCGCTC GCGCCTTCCT CCTGAACTGC ATGCTTCTGG GAGGCCGGAA GACCACGGAC 
ATCCCTCTGG AGGGCTACCT GCTGTCCCCC ATCCAGAGGA TCTGCAAGTA CCCACTCCTG 
CTCAAGGAGT TATCTAAGAG GACCCCGGGC AAACACCCTG ACCATTCCGC GGTACAGAGC 
GCCCTGCAAG CCATGAAGAC CGTCTGCTCC AACATCAATG AGACCAAGAG GCAGATGGAG 
AAGCTGGAGG CCCTGGAGCA GCTGCAGTCT CACATCGAAG GCTGGGAGGG CTCGAACCTC 
ACAGACATCT GCACCCAGCT TCTCCTTCAG GGCACTCTGC TGAAGATCTC TGCAGGCAAC 
ATCCAAGAGA GAGCCTTCTT CCTCTTCGAC AACTTGCTCG TCTACTGCAA GCGGAAATCT 
AGGGTCACTG GGAGCAAGAA ATCTACCAAG AGGACCAAGT CCATCAACGG CTCCCTGTAC 
ATCTTCAGGG GTCGGATCAA CACTGAGGTC ATGGAAGTGG AGAATGTGGA AGACGGGACA 
GCCGATTACC ACAGCAATGG CTACACCGTC ACCAATGGCT GGAAGATCCA CAATACAGCC 
AAAAACAAGT GGTTTGTGTG TATGGCCAAG ACAGCAGAGG AGAAGCAGAA GTGGCTGGAC 
GCCCTGATCC GAGAGCGGGA GCAGCGAGAG AGCCTGAAGC TGGGCATGGA GCGCGACGCA 
TACGTCATGA TTGCGGAGAA GGGGGAGAAG CTGTATCACA TGATGATGAG CAAGAAGGTG 
AACTTGATCA AGGACCGCCG ACGGAAGCTG AGCACCGTCC CCAAGTGCTT CCTTGGCAAT 
GAGTTTGTCG CCTGGCTCCT GGAAATTGGT GAGATCAGCA AGACAGAAGA AGGGGTCAAC 
TTGGGCCAGG CCCTGTTGGA GAATGGCATC ATCCACCACG TCTCCGACAA GCATCAGTTC 
AAGAACGAGC AGGTGATGTA TCGCTTCCGC TACGACGATG GCACCTACAA AGCCCGCAGC 
GAGCTGGAGG ACATCATGTC CAAGGGCGTG AGACTCTATT GCCGGCTTCA CAGCCTGTAC 
GCCCCCGTGA TCAAGGACCG TGATTACCAC CTGAAGACCT ACAAGTCCGT GGTCCCCGGG 
AGCAAGCTGG TCGACTGGCT CCTGGCACAG GGGGACTGCC AGACACGGGA GGAGGCGGTG 
GCGCTGGGTG TGGGCCTGTG CAACAACGGT TTCATGCACC ATGTTCTGGA GAAGAGCGAA 
TTCAAGGACG AGTCTCAGTA CTTCCGCTTC CATGCGGACG AGGAGATGGA AGGGACCAGC 
AGCAAGAACA AACAGCTTCG CAACGACTTC AAGCTAGTGG AGAACATCCT GGCCAAGCGG 
CTGCTGATCC CGCCGCAGGA GGATGACTAT GGCTTCGATC TTGAGGAGAA GAACAAGGCA 
GTGGTGGTGA AGTCCGTGCA GAGGGGTTCG CTGGCTGAGA TGGCTGGCCT GCAGGCGGGG 
AGGAAGATTT ACTCCATCAA CGAGGACCTG GTGTTCCTAC GGCCCTTCTC TGAGGTGGAG 
ACCATCCTTA ACCAGTCCTT CTGCTCCCGC CGCCCGCTGC GCCTCCTGGT GGCCACCAAG 
GCCAAAGAGA CCATCAAAAT CCCTGACCAC CCAGAGGCCC TGTCCTTCCA GATTCGAGGA 
ACAGCCCCGC CGTGTGTCTT TGCCGTGGGC AGAGGTTCTG AGGCTGTGGC TGCCGGGCTC 
TGCGCAGGCC AATGCATCCT GAAAGTCAAC GGCAACAGCG TGGCAAATGA TGGCGCCCTT 
GAAGTTCTGG AGCACTTCCA GGCTTTCCGC AGCCGCAGGG AGGAGGCCCT GGGCCTTTAC 
CAGTGGGTCT ACCACAGCCA CGAGGACGCC CAGCAGGCGA GAGCCAGCCA GGGTGCCCCG 
GATGAGGACC CCCAGGAGGA TGACTCAGTC CTGCCCCTGC TGTCCCTGGG TCCCCAGCTG 
AGCCTGCACG AGGACAGCGC TGTGGTCAGC CTGACGCTGG ACAATGTTCA CTTGGAGCAC 
GGTGTGGTTT ATGAATACGT GAGCACAGCA GGAGCCAAGT GTCACGTGCT GGAAAAGATC 
GTGGAGCCCC GAGGCTGTTT CCGCCTGGCT GCCAAGATCC TTGAGGCCTT TGCCGAGGAC 
GACAGCCTCT TCGTGCAGAA CTGTGGGCGG CTCATGGCCA TGGGCAGCGC TATCATCACC 
ATGTCCCACT ACGAGTTCCA CAACATCTGT GACACCAAGC TGGAGAGCAT TGGCCAGAGA 
ATCGCCTGCT ACCAGGAGTT TGCAGCCCAG CTGAAGAGCA GGGTCAGCCC CCCCTTCAAG 
CAGGCACCCC TGGAGGACCA CCCGCTGTGT GGCCTGGACT TCTGCCCTAC CAACTGCCAC 
ATCAACTTCA TGGAGGTGTC CTACCCCAAG ACCACCCCTT CAGTGGGCAG GTCCTTCAGC 
ATCCGCTTTG GGCGCAAACC CTCCCTCATC GGCCTTGACC CAGAACAAGG CCACCTGAAC 
CCCATGGCTT ACACCCAGCA CTGTATCACC ACCATGGCTG CCCCGTCCTG GAAGTGCGCG 
CCTGCTGTAG ATGGGGACTC TCAAAGCCAA GGTCTCATTG ACAGTATCTT CGTGTCAGCC 
AGTGGTGCCC TGAGCCAGCA AGAACGGGGC CTGAGCTTTC TGCTCAAGCA GGAGGACCGG 
GAGATCCAGG ACGCGTATCT GCAGCTCTTC ACTAAGCTGG ATGTGGCCCT CAAGGAGATG 
AAGCAGTATG TCACCCAGAT CAACAGGCTG CTGTCAACCA TCACAGAGCC CACGTCAGCT 
GCACCCTGTG ACCCACCCTT GGTGGAGGAG ACCTCATCTT CCCCACCGGC CAGTGAAGAG 
AGCGAAGTGG ACAGGACTGA CCATGGCGGC ATCAAGAAGG TGTGCTTCAA GGTGTCAGAG 
GACGAGCAGG AAGACTCGGG CCACGACACC ATGAGCTACC GAGACTCCTA TAGTGAGTGT 
AACAGCAATC GTGACTCTGT CCTGTCCTAC ACCAGCGTGA GAAGCAACAG TTCGTACCTG 
GGCAGTGATG AGACAGGCTC AGGGGATGAG CTGCCCTGTG ACATACGCAT CCCATCCGAC 
AAGCAGGACA AACTTCACGG CTGCCTGGAA CATCTCTTTA ACCAGGTGGA TTCCATCCAT 
GCCCTGCTCA AGGGGCCTGT GATGAGCAGG GCGTTTGAGG AGACCAGGCA TTTCCCCATG 
GAGCACAGCT GGCAAGAGTT CAAACAGAAA GAAGAATGCA CAGTCCGAGG CCGGAACTTG 
ATCCAGATCA GCATCCAGGA GGACCCTTGG AACCTACCCA GCTCCATCAG GACCCTGGTA 
GACAACATCC AGCGATATGT GGAAGATGGG AAGAACCAGC TGCTTCTGGC CCTGCTGAAA 
TGCACAGACA CGGAGCTGCA GCTGCGCAGG GATGCTGTCT TCTGTCAGGC CCTGGTGGCC 
GCCGTGTGCA CCTTCTCGGA GCAGCTGCTG GCCGCCCTCG ACTACCGCTA CAACAACAAC 
GGCGAGTATG AAGAGAGCAG CAGAGACGCC AGCCGCAAGT GGCTGGAGCA GGTGGCAGCC 
ACCGGTGTCC TGCTGCACTG GCAGTCCCTG CTGGCACCAG CCACCGTGAA AGAGGAACGG 
ACCATGCTGG AGGACATCTG GGTGACACTG TCGGAGCTGG ACAATGTCAC CTTCTCCTTT 
AAGCAGCTGG ATGAGAATTC TGTGGCCAAC ACCAACGTCT TCTACCACAT TGAGGGCAGC 
AGGCAGGCAC TGAAGGTAGT CTTCTACCTC GATGGCTTCC ACTTCTCCAG GCTGCCCTCT 
CGCCTGGAGG GTGGGGCCAG CCTCAGGCTG CACACCGTGC TATTCACAAA AGCTCTGGAG 
AATGTGGAAG GGCCGTCGCC CCCAGGAAGC CAGGCTGCAG AAGATCTGCA GCAGGAGATC 
AATGCGCAGT CCCTGGAGAA GGTTCAGCAG TACTATAGAA GGCTCAGGGC CTTCTACCTG 
GAGCGGTCCA ACCTCCCCAC AGATGCTACC ACCACAGCTG TGAAGATCGA CCAGCTGATC 
CGTCCCATCA ACGCCCTGGA CGAGCTCTAC CGCCTCATGA AGTCCTTCGT GCACCCGAAA 
GCTGGTGCTG GTGGGAGCCT AGGTGCCGGC CTCGTCCCCG TCTCCTCTGA GCTCTGCTAC 
CGTCTGGGGG CGTGTCAGAT CACCATGTGT GGCACCGGCA TGCAGCGGAG CACCCTGAGC 
GTGTCCTTGG AACAAGCAGC CATCTTGGCT CGGAGCCACG GGCTGCTGCC CAAGTGTGTT 
ATGCAGGCCA CAGACATCAT GCGCAAGCAG GGCCCCCGAG TGGAGATCCT GGCAAAAAAC 
CTCCGCATCA AAGACCCAAT GCCCCAAGGT GCACCACGCC TCTACCGCCT CTGCCAGCCT 
CCGGTGGATG GAGACCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001129190.1
CDS	106..5046
Translation	MEAPGSGSGDGGGDPGGDGAHPDARGPSSGPCAAARDSERQLRLRLCVLNEILATERDYVGTLRFLQSAFLQRIRQNVADSVDKGLTEENVKILFSNIEDILEVHKDFLAALEYCLHPEPQSQHELGNVFLKFKDKFCVYEEYCSNHEKALRLLVELNKVPAARAFLLNCMLLGGRKTTDIPLEGYLLSPIQRICKYPLLLKELSKRTPGKHPDHSAVQSALQAMKTVCSNINETKRQMEKLEALEQLQSHIEGWEGSNLTDICTQLLLQGTLLKISAGNIQERAFFLFDNLLVYCKRKSRVTGSKKSTKRTKSINGSLYIFRGRINTEVMEVENVEDGTADYHSNGYTVTNGWKIHNTAKNKWFVCMAKTAEEKQKWLDALIREREQRESLKLGMERDAYVMIAEKGEKLYHMMMSKKVNLIKDRRRKLSTVPKCFLGNEFVAWLLEIGEISKTEEGVNLGQALLENGIIHHVSDKHQFKNEQVMYRFRYDDGTYKARSELEDIMSKGVRLYCRLHSLYAPVIKDRDYHLKTYKSVVPGSKLVDWLLAQGDCQTREEAVALGVGLCNNGFMHHVLEKSEFKDESQYFRFHADEEMEGTSSKNKQLRNDFKLVENILAKRLLIPPQEDDYGFDLEEKNKAVVVKSVQRGSLAEMAGLQAGRKIYSINEDLVFLRPFSEVETILNQSFCSRRPLRLLVATKAKETIKIPDHPEALSFQIRGTAPPCVFAVGRGSEAVAAGLCAGQCILKVNGNSVANDGALEVLEHFQAFRSRREEALGLYQWVYHSHEDAQQARASQGAPDEDPQEDDSVLPLLSLGPQLSLHEDSAVVSLTLDNVHLEHGVVYEYVSTAGAKCHVLEKIVEPRGCFRLAAKILEAFAEDDSLFVQNCGRLMAMGSAIITMSHYEFHNICDTKLESIGQRIACYQEFAAQLKSRVSPPFKQAPLEDHPLCGLDFCPTNCHINFMEVSYPKTTPSVGRSFSIRFGRKPSLIGLDPEQGHLNPMAYTQHCITTMAAPSWKCAPAVDGDSQSQGLIDSIFVSASGALSQQERGLSFLLKQEDREIQDAYLQLFTKLDVALKEMKQYVTQINRLLSTITEPTSAAPCDPPLVEETSSSPPASEESEVDRTDHGGIKKVCFKVSEDEQEDSGHDTMSYRDSYSECNSNRDSVLSYTSVRSNSSYLGSDETGSGDELPCDIRIPSDKQDKLHGCLEHLFNQVDSIHALLKGPVMSRAFEETRHFPMEHSWQEFKQKEECTVRGRNLIQISIQEDPWNLPSSIRTLVDNIQRYVEDGKNQLLLALLKCTDTELQLRRDAVFCQALVAAVCTFSEQLLAALDYRYNNNGEYEESSRDASRKWLEQVAATGVLLHWQSLLAPATVKEERTMLEDIWVTLSELDNVTFSFKQLDENSVANTNVFYHIEGSRQALKVVFYLDGFHFSRLPSRLEGGASLRLHTVLFTKALENVEGPSPPGSQAAEDLQQEINAQSLEKVQQYYRRLRAFYLERSNLPTDATTTAVKIDQLIRPINALDELYRLMKSFVHPKAGAGGSLGAGLVPVSSELCYRLGACQITMCGTGMQRSTLSVSLEQAAILARSHGLLPKCVMQATDIMRKQGPRVEILAKNLRIKDPMPQGAPRLYRLCQPPVDGDL

Target ORF information:

RefSeq Version	NM_001135718.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 (Prex1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001135718.1

ORF Insert Sequence:

ATGGAGGCGC CCGGCAGCGG TAGTGGCGAT GGCGGCGGGG ACCCAGGCGG GGACGGTGCG 
CATCCCGATG CTCGCGGTCC CAGCTCCGGG CCATGCGCGG CCGCCCGCGA CTCGGAGCGC 
CAGCTGCGCC TCCGTCTGTG CGTACTCAAC GAGATCCTGG CCACCGAGCG CGACTACGTG 
GGCACCTTGC GTTTCCTGCA GTCGGCGTTC CTACAGCGGA TCCGGCAGAA TGTGGCCGAC 
TCTGTGGACA AGGGCCTCAC GGAAGAGAAT GTCAAGATCC TCTTCTCCAA CATTGAGGAC 
ATCTTGGAGG TCCATAAGGA TTTTTTGGCT GCCCTGGAAT ACTGCCTACA TCCGGAGCCC 
CAGTCTCAGC ACGAACTTGG GAATGTTTTC TTGAAATTTA AGGACAAGTT CTGTGTGTAT 
GAGGAGTACT GCAGTAACCA CGAGAAGGCC CTGCGTCTGT TGGTGGAGCT CAACAAGGTC 
CCTGCCGCTC GCGCCTTCCT CCTGAACTGC ATGCTTCTGG GAGGCCGGAA GACCACGGAC 
ATCCCTCTGG AGGGCTACCT GCTGTCCCCC ATCCAGAGGA TCTGCAAGTA CCCACTCCTG 
CTCAAGGAGT TATCTAAGAG GACCCCGGGC AAACACCCTG ACCATTCCGC GGTACAGAGC 
GCCCTGCAAG CCATGAAGAC CGTCTGCTCC AACATCAATG AGACCAAGAG GCAGATGGAG 
AAGCTGGAGG CCCTGGAGCA GCTGCAGTCT CACATCGAAG GCTGGGAGGG CTCGAACCTC 
ACAGACATCT GCACCCAGCT TCTCCTTCAG GGCACTCTGC TGAAGATCTC TGCAGGCAAC 
ATCCAAGAGA GAGCCTTCTT CCTCTTCGAC AACTTGCTCG TCTACTGCAA GCGGAAATCT 
AGGGTCACTG GGAGCAAGAA ATCTACCAAG AGGACCAAGT CCATCAACGG CTCCCTGTAC 
ATCTTCAGGG GTCGGATCAA CACTGAGGTC ATGGAAGTGG AGAATGTGGA AGACGGGACA 
GCCGATTACC ACAGCAATGG CTACACCGTC ACCAATGGCT GGAAGATCCA CAATACAGCC 
AAAAACAAGT GGTTTGTGTG TATGGCCAAG ACAGCAGAGG AGAAGCAGAA GTGGCTGGAC 
GCCCTGATCC GAGAGCGGGA GCAGCGAGAG AGCCTGAAGC TGGGCATGGA GCGCGACGCA 
TACGTCATGA TTGCGGAGAA GGGGGAGAAG CTGTATCACA TGATGATGAG CAAGAAGGTG 
AACTTGATCA AGGACCGCCG ACGGAAGCTG AGCACCGTCC CCAAGTGCTT CCTTGGCAAT 
GAGTTTGTCG CCTGGCTCCT GGAAATTGGT GAGATCAGCA AGACAGAAGA AGGGGTCAAC 
TTGGGCCAGG CCCTGTTGGA GAATGGCATC ATCCACCACG TCTCCGACAA GCATCAGTTC 
AAGAACGAGC AGGTGATGTA TCGCTTCCGC TACGACGATG GCACCTACAA AGCCCGCAGC 
GAGCTGGAGG ACATCATGTC CAAGGGCGTG AGACTCTATT GCCGGCTTCA CAGCCTGTAC 
GCCCCCGTGA TCAAGGACCG TGATTACCAC CTGAAGACCT ACAAGTCCGT GGTCCCCGGG 
AGCAAGCTGG TCGACTGGCT CCTGGCACAG GGGGACTGCC AGACACGGGA GGAGGCGGTG 
GCGCTGGGTG TGGGCCTGTG CAACAACGGT TTCATGCACC ATGTTCTGGA GAAGAGCGAA 
TTCAAGGACG AGTCTCAGTA CTTCCGCTTC CATGCGGACG AGGAGATGGA AGGGACCAGC 
AGCAAGAACA AACAGCTTCG CAACGACTTC AAGCTAGTGG AGAACATCCT GGCCAAGCGG 
CTGCTGATCC CGCCGCAGGA GGATGACTAT GGCTTCGATC TTGAGGAGAA GAACAAGGCA 
GTGGTGGTGA AGTCCGTGCA GAGGGGTTCG CTGGCTGAGA TGGCTGGCCT GCAGGCGGGG 
AGGAAGATTT ACTCCATCAA CGAGGACCTG GTGTTCCTAC GGCCCTTCTC TGAGGTGGAG 
ACCATCCTTA ACCAGTCCTT CTGCTCCCGC CGCCCGCTGC GCCTCCTGGT GGCCACCAAG 
GCCAAAGAGA CCATCAAAAT CCCTGACCAC CCAGAGGCCC TGTCCTTCCA GATTCGAGGA 
ACAGCCCCGC CGTGTGTCTT TGCCGTGGGC AGAGGTTCTG AGGCTGTGGC TGCCGGGCTC 
TGCGCAGGCC AATGCATCCT GAAAGTCAAC GGCAACAGCG TGGCAAATGA TGGCGCCCTT 
GAAGTTCTGG AGCACTTCCA GGCTTTCCGC AGCCGCAGGG AGGAGGCCCT GGGCCTTTAC 
CAGTGGGTCT ACCACAGCCA CGAGGACGCC CAGCAGGCGA GAGCCAGCCA GGGTGCCCCG 
GATGAGGACC CCCAGGAGGA TGACTCAGTC CTGCCCCTGC TGTCCCTGGG TCCCCAGCTG 
AGCCTGCACG AGGACAGCGC TGTGGTCAGC CTGACGCTGG ACAATGTTCA CTTGGAGCAC 
GGTGTGGTTT ATGAATACGT GAGCACAGCA GGAGCCAAGT GTCACGTGCT GGAAAAGATC 
GTGGAGCCCC GAGGCTGTTT CCGCCTGGCT GCCAAGATCC TTGAGGCCTT TGCCGAGGAC 
GACAGCCTCT TCGTGCAGAA CTGTGGGCGG CTCATGGCCA TGGGCAGCGC TATCATCACC 
ATGTCCCACT ACGAGTTCCA CAACATCTGT GACACCAAGC TGGAGAGCAT TGGCCAGAGA 
ATCGCCTGCT ACCAGGAGTT TGCAGCCCAG CTGAAGAGCA GGGTCAGCCC CCCCTTCAAG 
CAGGCACCCC TGGAGGACCA CCCGCTGTGT GGCCTGGACT TCTGCCCTAC CAACTGCCAC 
ATCAACTTCA TGGAGGTGTC CTACCCCAAG ACCACCCCTT CAGTGGGCAG GTCCTTCAGC 
ATCCGCTTTG GGCGCAAACC CTCCCTCATC GGCCTTGACC CAGAACAAGG CCACCTGAAC 
CCCATGGCTT ACACCCAGCA CTGTATCACC ACCATGGCTG CCCCGTCCTG GAAGTGCGCG 
CCTGCTGTAG ATGGGGACTC TCAAAGCCAA GGTCTCATTG ACAGTATCTT CGTGTCAGCC 
AGTGGTGCCC TGAGCCAGCA AGAACGGGGC CTGAGCTTTC TGCTCAAGCA GGAGGACCGG 
GAGATCCAGG ACGCGTATCT GCAGCTCTTC ACTAAGCTGG ATGTGGCCCT CAAGGAGATG 
AAGCAGTATG TCACCCAGAT CAACAGGCTG CTGTCAACCA TCACAGAGCC CACGTCAGCT 
GCACCCTGTG ACCCACCCTT GGTGGAGGAG ACCTCATCTT CCCCACCGGC CAGTGAAGAG 
AGCGAAGTGG ACAGGACTGA CCATGGCGGC ATCAAGAAGG TGTGCTTCAA GGTGTCAGAG 
GACGAGCAGG AAGACTCGGG CCACGACACC ATGAGCTACC GAGACTCCTA TAGTGAGTGT 
AACAGCAATC GTGACTCTGT CCTGTCCTAC ACCAGCGTGA GAAGCAACAG TTCGTACCTG 
GGCAGTGATG AGACAGGCTC AGGGGATGAG CTGCCCTGTG ACATACGCAT CCCATCCGAC 
AAGCAGGACA AACTTCACGG CTGCCTGGAA CATCTCTTTA ACCAGGTGGA TTCCATCCAT 
GCCCTGCTCA AGGGGCCTGT GATGAGCAGG GCGTTTGAGG AGACCAGGCA TTTCCCCATG 
GAGCACAGCT GGCAAGAGTT CAAACAGAAA GAAGAATGCA CAGTCCGAGG CCGGAACTTG 
ATCCAGATCA GCATCCAGGA GGACCCTTGG AACCTACCCA GCTCCATCAG GACCCTGGTA 
GACAACATCC AGCGATATGT GGAAGATGGG AAGAACCAGC TGCTTCTGGC CCTGCTGAAA 
TGCACAGACA CGGAGCTGCA GCTGCGCAGG GATGCTGTCT TCTGTCAGGC CCTGGTGGCC 
GCCGTGTGCA CCTTCTCGGA GCAGCTGCTG GCCGCCCTCG ACTACCGCTA CAACAACAAC 
GGCGAGTATG AAGAGAGCAG CAGAGACGCC AGCCGCAAGT GGCTGGAGCA GGTGGCAGCC 
ACCGGTGTCC TGCTGCACTG GCAGTCCCTG CTGGCACCAG CCACCGTGAA AGAGGAACGG 
ACCATGCTGG AGGACATCTG GGTGACACTG TCGGAGCTGG ACAATGTCAC CTTCTCCTTT 
AAGCAGCTGG ATGAGAATTC TGTGGCCAAC ACCAACGTCT TCTACCACAT TGAGGGCAGC 
AGGCAGGCAC TGAAGGTAGT CTTCTACCTC GATGGCTTCC ACTTCTCCAG GCTGCCCTCT 
CGCCTGGAGG GTGGGGCCAG CCTCAGGCTG CACACCGTGC TATTCACAAA AGCTCTGGAG 
AATGTGGAAG GGCCGTCGCC CCCAGGAAGC CAGGCTGCAG AAGATCTGCA GCAGGAGATC 
AATGCGCAGT CCCTGGAGAA GGTTCAGCAG TACTATAGAA GGCTCAGGGC CTTCTACCTG 
GAGCGGTCCA ACCTCCCCAC AGATGCTACC ACCACAGCTG TGAAGATCGA CCAGCTGATC 
CGTCCCATCA ACGCCCTGGA CGAGCTCTAC CGCCTCATGA AGTCCTTCGT GCACCCGAAA 
GCTGGTGCTG GTGGGAGCCT AGGTGCCGGC CTCGTCCCCG TCTCCTCTGA GCTCTGCTAC 
CGTCTGGGGG CGTGTCAGAT CACCATGTGT GGCACCGGCA TGCAGCGGAG CACCCTGAGC 
GTGTCCTTGG AACAAGCAGC CATCTTGGCT CGGAGCCACG GGCTGCTGCC CAAGTGTGTT 
ATGCAGGCCA CAGACATCAT GCGCAAGCAG GGCCCCCGAG TGGAGATCCT GGCAAAAAAC 
CTCCGCATCA AAGACCCAAT GCCCCAAGGT GCACCACGCC TCTACCGCCT CTGCCAGCCT 
CCGGTGGATG GAGACCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis.
Oncogene28(16)1853-63(2009 Apr)
Qin J,Xie Y,Wang B,Hoshino M,Wolff DW,Zhao J,Scofield MA,Dowd FJ,Lin MF,Tu Y

P-Rex1 - a multidomain protein that regulates neurite differentiation.
Journal of cell science121(Pt 17)2892-903(2008 Sep)
Waters JE,Astle MV,Ooms LM,Balamatsias D,Gurung R,Mitchell CA

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Prex1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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