Sulf2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Sulf2
Entrez Gene ID	311642
Full Name	sulfatase 2
General protein information	Preferred Names sulfatase 2 Names extracellular sulfatase Sulf-2 sulfatase FP2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q42

mRNA and Protein(s)

mRNA	Protein	Name
NM_001034927.1	NP_001030099.1	extracellular sulfatase Sulf-2 precursor
XM_006235596.3	XP_006235658.1	extracellular sulfatase Sulf-2 isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	SULF2	NP_001179867.1
Xenopus tropicalis (tropical clawed frog)	sulf2	NP_001005661.1
Canis lupus familiaris (dog)	SULF2	NP_001041555.1
Mus musculus (house mouse)	Sulf2	NP_001239508.1
Rattus norvegicus (Norway rat)	Sulf2	NP_001030099.1
Pan troglodytes (chimpanzee)	SULF2	XP_514701.4
Gallus gallus (chicken)	SULF2	XP_004947107.1
Homo sapiens (human)	SULF2	NP_001155313.1
	SULF2	XP_001106412.2
Danio rerio (zebrafish)	sulf2b	NP_001003833.2

Gene Ontology
Bibliography

Related articles in PubMed

Expression of Sulf1 and Sulf2 in cartilage, bone and endochondral fracture healing.
Zaman G, Staines KA, Farquharson C, Newton PT, Dudhia J, Chenu C, Pitsillides AA, Dhoot GK
Histochemistry and cell biology145(1)67-79(2016 Jan)

Sulf1 and Sulf2 expression in the nervous system and its role in limiting neurite outgrowth in vitro.
Joy MT, Vrbova G, Dhoot GK, Anderson PN
Experimental neurology263150-60(2015 Jan)

Activation of the transcription factor GLI1 by WNT signaling underlies the role of SULFATASE 2 as a regulator of tissue regeneration.
Nakamura I, Fernandez-Barrena MG, Ortiz-Ruiz MC, Almada LL, Hu C, Elsawa SF, Mills LD, Romecin PA, Gulaid KH, Moser CD, Han JJ, Vrabel A, Hanse EA, Akogyeram NA, Albrecht JH, Monga SP, Sanderson SO, Prieto J, Roberts LR, Fernandez-Zapico ME
The Journal of biological chemistry288(29)21389-98(2013 Jul)

WT1-dependent sulfatase expression maintains the normal glomerular filtration barrier.
Schumacher VA, Schl?tzer-Schrehardt U, Karumanchi SA, Shi X, Zaia J, Jeruschke S, Zhang D, Pavenst?dt H, Pavenstaedt H, Drenckhan A, Amann K, Ng C, Hartwig S, Ng KH, Ho J, Kreidberg JA, Taglienti M, Royer-Pokora B, Ai X
Journal of the American Society of Nephrology : JASN22(7)1286-96(2011 Jul)

Extracellular sulfatases support cartilage homeostasis by regulating BMP and FGF signaling pathways.
Otsuki S, Hanson SR, Miyaki S, Grogan SP, Kinoshita M, Asahara H, Wong CH, Lotz MK
Proceedings of the National Academy of Sciences of the United States of America107(22)10202-7(2010 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Examination of epiphyseal growth plates revealed differential, inverse patterns of SULF1 and SULF2 expressions, with the former enriched in quiescent and the latter in hypertrophic chondrocyte zones.
Title: Expression of Sulf1 and Sulf2 in cartilage, bone and endochondral fracture healing.

It is proposed that Sulf1, Sulf2 and ErbB1 are involved in the inhibition of neurite outgrowth and may regulate structural plasticity and regeneration in the nervous system.
Title: Sulf1 and Sulf2 expression in the nervous system and its role in limiting neurite outgrowth in vitro.

the cleavage of rat Sulf2 occurs at two arginine residues, 543 and 570, in the hydrophilic domain.
Title: Proteolytic cleavage of the rat heparan sulfate 6-O-endosulfatase SulfFP2 by furin-type proprotein convertases.

The following Sulf2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sulf2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa09046	NM_001034927.1 Latest version!	Rattus norvegicus sulfatase 2 (Sulf2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
ORa09046	XM_006235596.3 Latest version!	Rattus norvegicus sulfatase 2 (Sulf2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Sulf2 ( NM_001034927.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001030099.1 Rattus norvegicus sulfatase 2 (Sulf2), mRNA.

Price & Availability↑

CloneID	ORa09046
Clone ID Related Accession (Same CDS sequence)	NM_001034927.1 , XM_006235596.3
Accession Version	NM_001034927.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2628bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Rattus norvegicus(Norway rat)
Product	extracellular sulfatase Sulf-2 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY742216.1. On or before Jul 24, 2006 this sequence version replaced XM_230861.4, XM_001072989.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY742216.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCACCCC CTGGCCTGCC ACTGTGGCTG CTGTCCACCG CTCTCTTCTC CCTTCTGGCT 
GGCAGCTCAG CCTTCCTCTC CTATCCCCGC CTGAAGGGTC GCTTCCAGAG GGACCGCAGG 
AATATCCGGC CCAACATCAT CTTGGTGCTC ACGGATGACC AGGACGTGGA GCTGGGCTCC 
ATGCAGGTGA TGAACAAGAC ACGACGTATC ATGGAGCAGG GCGGGGCACA CTTCATCAAC 
GCCTTCGTGA CTACACCTAT GTGCTGTCCC TCTCGCTCCT CCATCCTCAC CGGCAAGTAC 
GTCCACAATC ACAACACCTA CACCAACAAC GAGAACTGTT CCTCGCCCTC CTGGCAGGCA 
CAGCATGAGA GCCGAACCTT CGCCGTGTAC CTCAACAGCA CTGGCTACCG GACAGCTTTC 
TTCGGAAAAT ACCTCAATGA ATACAACGGC TCATATGTGC CGCCTGGCTG GAAGGAGTGG 
GTTGGACTCC TTAAGAACTC GCGTTTTTAT AACTACACAC TCTGCCGGAA TGGGATGAAG 
GAGAAGCATG GCTCTGACTA CTCCACGGAT TACCTCACAG ATCTCATCAC CAATGACAGT 
GTGAGCTTCT TCCGAACATC CAAGAAGATG TACCCACACA GACCTGTGCT CATGGTCATC 
AGCCACGCAG CTCCCCACGG CCCTGAGGAC TCAGCACCCC AGTACTCACG CCTCTTCCCC 
AATGCATCCC AGCACATCAC ACCGAGTTAC AACTATGCAC CCAACCCAGA CAAGCACTGG 
ATCATGCGCT ACACGGGACC CATGAAGCCC ATTCACATGG AATTCACCAA CATGCTACAG 
CGCAAACGCC TGCAGACCCT CATGTCTGTG GACGACTCCA TGGAGACGAT CTATGACATG 
CTAGTGGAGA CGGGCGAGCT GGACAATACC TACATCGTGT ACACCGCCGA CCACGGCTAC 
CACATTGGCC AGTTTGGCCT GGTGAAGGGC AAGTCCATGC CCTATGAGTT TGACATCAGG 
GTCCCGTTCT ATGTGCGGGG CCCCAGCGTG GAAGCTGGCT CTCTGAACCC CCACATCGTC 
CTCAACATTG ACCTGGCCCC CACCATACTG GATATCGCTG GACTGGACAT CCCTGCAGAC 
ATGGACGGGA AGTCCATCCT CAAACTACTG GACTCAGAGC GGCCAGTGAA CCGGTTCCAC 
CTGAAAAAGA AGCTGAGGGT CTGGCGAGAC TCCTTCCTGG TGGAAAGAGG CAAACTGCTC 
CACAAGAGGG AGGGTGACAA AGTGAACGCC CAGGAGGAGA ACTTCCTGCC CAAGTATCAG 
CGTGTGAAGG ACCTGTGTCA AAGGGCTGAG TACCAGACAG CATGCGAGCA GCTAGGGCAG 
AAGTGGCAGT GTGTAGAGGA CGCTTCTGGG GCGCTGAAGC TGCACAAGTG TAAAGGCCCG 
GTGCGGTTCG GGGGCGGTGG TGACAGAGCC CTCTCCAACC TGGTGCCCAA GTACGACGGC 
CAAAGCAGCG AGGCCTGCAG CTGTGACGGC GGCGGCGGCG GAGGGGACTA CAAACTGGGC 
CTGGCTGGAC GCCGGAAGCT CTTTAAGAAA AAGTACAAGA CCAGCTATGC CCGGAACCGC 
TCCATCCGCT CTGTGGCCAT CGAGGTGGAT GGCGAGGTAT ACCACGTAGG CTTGGATAAC 
ATGCCGCTGC CCCGCAACCT CACCAAGCGT CACTGGCCAG GGGCCCCTGA AGACCAGGAT 
GACAAGGATG GTGGAAGTTT CAGTGGTACT GGTGGCCTTC CAGATTATTC TGCCCCCAAT 
CCCATTAAAG TGACCCATCG GTGCTACATC CTTGAGAATG ACACAGTCCA GTGTGACTTG 
GACCTGTACA AGTCCCTGCA GGCTTGGAAA GACCACAAAT TGCACATCGA CCATGAGATT 
GAAACCCTGC AGAACAAAAT TAAGAACCTT CGAGAAGTCA GGGGTCACCT GAAGAAGAAG 
CGGCCAGAAG AATGTGACTG TCACAAAGTC AGTTACCACA GCCAACACAA AGGCCGCCTC 
AAGCACAAGG GCTCCAGCCT GCACCCTTTC AGGAAGGGTC TGCAGGAGAA AGACAAGGTG 
TGGCTGTTGC GGGAGCAGAA ACGCAAGAAG AAACTGCGCA AGCTGCTGAA GCGACTGCAG 
AACAATGACA CGTGCAGCAT GCCGGGCCTC ACGTGCTTTA CTCACGACAA CCACCACTGG 
CAGACCGCGC CGCTCTGGAC GTTGGGACCC TTCTGCGCCT GCACCAGCGC CAACAATAAC 
ACGTACTGGT GCCTGCGGAC CATCAACGAG ACCCACAACT TCCTCTTCTG TGAATTCGCA 
ACTGGCTTCA TAGAATACTT TGACCTCAGT ACGGACCCCT ACCAGCTGAT GAACGCGGTC 
AACACACTGG ACAGGGACGT TCTCAACCAG CTGCACGTCC AGCTCATGGA GCTAAGGAGC 
TGCAAAGGCT ACAAGCAGTG TAACCCCCGG ACCCGCAATA TGGACCTGGG GCTTAGAGAC 
GGAGGAAGCT ATGAGCAATA CAGGCAGTTT CAGCGTCGAA AATGGCCAGA AATGAAGAGA 
CCCTCTTCCA AATCACTGGG ACAGCTATGG GAAGGTTGGG AAGGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001030099.1
CDS	651..3278
Translation	MAPPGLPLWLLSTALFSLLAGSSAFLSYPRLKGRFQRDRRNIRPNIILVLTDDQDVELGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGMKEKHGSDYSTDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYDMLVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPSVEAGSLNPHIVLNIDLAPTILDIAGLDIPADMDGKSILKLLDSERPVNRFHLKKKLRVWRDSFLVERGKLLHKREGDKVNAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDASGALKLHKCKGPVRFGGGGDRALSNLVPKYDGQSSEACSCDGGGGGGDYKLGLAGRRKLFKKKYKTSYARNRSIRSVAIEVDGEVYHVGLDNMPLPRNLTKRHWPGAPEDQDDKDGGSFSGTGGLPDYSAPNPIKVTHRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEECDCHKVSYHSQHKGRLKHKGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTCSMPGLTCFTHDNHHWQTAPLWTLGPFCACTSANNNTYWCLRTINETHNFLFCEFATGFIEYFDLSTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLRDGGSYEQYRQFQRRKWPEMKRPSSKSLGQLWEGWEG

Target ORF information:

RefSeq Version	NM_001034927.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus sulfatase 2 (Sulf2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001034927.1

ORF Insert Sequence:

ATGGCACCCC CTGGCCTGCC ACTGTGGCTG CTGTCCACCG CTCTCTTCTC CCTTCTGGCT 
GGCAGCTCAG CCTTCCTCTC CTATCCCCGC CTGAAGGGTC GCTTCCAGAG GGACCGCAGG 
AATATCCGGC CCAACATCAT CTTGGTGCTC ACGGATGACC AGGACGTGGA GCTGGGCTCC 
ATGCAGGTGA TGAACAAGAC ACGACGTATC ATGGAGCAGG GCGGGGCACA CTTCATCAAC 
GCCTTCGTGA CTACACCTAT GTGCTGTCCC TCTCGCTCCT CCATCCTCAC CGGCAAGTAC 
GTCCACAATC ACAACACCTA CACCAACAAC GAGAACTGTT CCTCGCCCTC CTGGCAGGCA 
CAGCATGAGA GCCGAACCTT CGCCGTGTAC CTCAACAGCA CTGGCTACCG GACAGCTTTC 
TTCGGAAAAT ACCTCAATGA ATACAACGGC TCATATGTGC CGCCTGGCTG GAAGGAGTGG 
GTTGGACTCC TTAAGAACTC GCGTTTTTAT AACTACACAC TCTGCCGGAA TGGGATGAAG 
GAGAAGCATG GCTCTGACTA CTCCACGGAT TACCTCACAG ATCTCATCAC CAATGACAGT 
GTGAGCTTCT TCCGAACATC CAAGAAGATG TACCCACACA GACCTGTGCT CATGGTCATC 
AGCCACGCAG CTCCCCACGG CCCTGAGGAC TCAGCACCCC AGTACTCACG CCTCTTCCCC 
AATGCATCCC AGCACATCAC ACCGAGTTAC AACTATGCAC CCAACCCAGA CAAGCACTGG 
ATCATGCGCT ACACGGGACC CATGAAGCCC ATTCACATGG AATTCACCAA CATGCTACAG 
CGCAAACGCC TGCAGACCCT CATGTCTGTG GACGACTCCA TGGAGACGAT CTATGACATG 
CTAGTGGAGA CGGGCGAGCT GGACAATACC TACATCGTGT ACACCGCCGA CCACGGCTAC 
CACATTGGCC AGTTTGGCCT GGTGAAGGGC AAGTCCATGC CCTATGAGTT TGACATCAGG 
GTCCCGTTCT ATGTGCGGGG CCCCAGCGTG GAAGCTGGCT CTCTGAACCC CCACATCGTC 
CTCAACATTG ACCTGGCCCC CACCATACTG GATATCGCTG GACTGGACAT CCCTGCAGAC 
ATGGACGGGA AGTCCATCCT CAAACTACTG GACTCAGAGC GGCCAGTGAA CCGGTTCCAC 
CTGAAAAAGA AGCTGAGGGT CTGGCGAGAC TCCTTCCTGG TGGAAAGAGG CAAACTGCTC 
CACAAGAGGG AGGGTGACAA AGTGAACGCC CAGGAGGAGA ACTTCCTGCC CAAGTATCAG 
CGTGTGAAGG ACCTGTGTCA AAGGGCTGAG TACCAGACAG CATGCGAGCA GCTAGGGCAG 
AAGTGGCAGT GTGTAGAGGA CGCTTCTGGG GCGCTGAAGC TGCACAAGTG TAAAGGCCCG 
GTGCGGTTCG GGGGCGGTGG TGACAGAGCC CTCTCCAACC TGGTGCCCAA GTACGACGGC 
CAAAGCAGCG AGGCCTGCAG CTGTGACGGC GGCGGCGGCG GAGGGGACTA CAAACTGGGC 
CTGGCTGGAC GCCGGAAGCT CTTTAAGAAA AAGTACAAGA CCAGCTATGC CCGGAACCGC 
TCCATCCGCT CTGTGGCCAT CGAGGTGGAT GGCGAGGTAT ACCACGTAGG CTTGGATAAC 
ATGCCGCTGC CCCGCAACCT CACCAAGCGT CACTGGCCAG GGGCCCCTGA AGACCAGGAT 
GACAAGGATG GTGGAAGTTT CAGTGGTACT GGTGGCCTTC CAGATTATTC TGCCCCCAAT 
CCCATTAAAG TGACCCATCG GTGCTACATC CTTGAGAATG ACACAGTCCA GTGTGACTTG 
GACCTGTACA AGTCCCTGCA GGCTTGGAAA GACCACAAAT TGCACATCGA CCATGAGATT 
GAAACCCTGC AGAACAAAAT TAAGAACCTT CGAGAAGTCA GGGGTCACCT GAAGAAGAAG 
CGGCCAGAAG AATGTGACTG TCACAAAGTC AGTTACCACA GCCAACACAA AGGCCGCCTC 
AAGCACAAGG GCTCCAGCCT GCACCCTTTC AGGAAGGGTC TGCAGGAGAA AGACAAGGTG 
TGGCTGTTGC GGGAGCAGAA ACGCAAGAAG AAACTGCGCA AGCTGCTGAA GCGACTGCAG 
AACAATGACA CGTGCAGCAT GCCGGGCCTC ACGTGCTTTA CTCACGACAA CCACCACTGG 
CAGACCGCGC CGCTCTGGAC GTTGGGACCC TTCTGCGCCT GCACCAGCGC CAACAATAAC 
ACGTACTGGT GCCTGCGGAC CATCAACGAG ACCCACAACT TCCTCTTCTG TGAATTCGCA 
ACTGGCTTCA TAGAATACTT TGACCTCAGT ACGGACCCCT ACCAGCTGAT GAACGCGGTC 
AACACACTGG ACAGGGACGT TCTCAACCAG CTGCACGTCC AGCTCATGGA GCTAAGGAGC 
TGCAAAGGCT ACAAGCAGTG TAACCCCCGG ACCCGCAATA TGGACCTGGG GCTTAGAGAC 
GGAGGAAGCT ATGAGCAATA CAGGCAGTTT CAGCGTCGAA AATGGCCAGA AATGAAGAGA 
CCCTCTTCCA AATCACTGGG ACAGCTATGG GAAGGTTGGG AAGGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Sulf2 ( XM_006235596.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006235658.1 Rattus norvegicus sulfatase 2 (Sulf2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa09046
Clone ID Related Accession (Same CDS sequence)	NM_001034927.1 , XM_006235596.3
Accession Version	XM_006235596.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2628bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	extracellular sulfatase Sulf-2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006235596.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCACCCC CTGGCCTGCC ACTGTGGCTG CTGTCCACCG CTCTCTTCTC CCTTCTGGCT 
GGCAGCTCAG CCTTCCTCTC CTATCCCCGC CTGAAGGGTC GCTTCCAGAG GGACCGCAGG 
AATATCCGGC CCAACATCAT CTTGGTGCTC ACGGATGACC AGGACGTGGA GCTGGGCTCC 
ATGCAGGTGA TGAACAAGAC ACGACGTATC ATGGAGCAGG GCGGGGCACA CTTCATCAAC 
GCCTTCGTGA CTACACCTAT GTGCTGTCCC TCTCGCTCCT CCATCCTCAC CGGCAAGTAC 
GTCCACAATC ACAACACCTA CACCAACAAC GAGAACTGTT CCTCGCCCTC CTGGCAGGCA 
CAGCATGAGA GCCGAACCTT CGCCGTGTAC CTCAACAGCA CTGGCTACCG GACAGCTTTC 
TTCGGAAAAT ACCTCAATGA ATACAACGGC TCATATGTGC CGCCTGGCTG GAAGGAGTGG 
GTTGGACTCC TTAAGAACTC GCGTTTTTAT AACTACACAC TCTGCCGGAA TGGGATGAAG 
GAGAAGCATG GCTCTGACTA CTCCACGGAT TACCTCACAG ATCTCATCAC CAATGACAGT 
GTGAGCTTCT TCCGAACATC CAAGAAGATG TACCCACACA GACCTGTGCT CATGGTCATC 
AGCCACGCAG CTCCCCACGG CCCTGAGGAC TCAGCACCCC AGTACTCACG CCTCTTCCCC 
AATGCATCCC AGCACATCAC ACCGAGTTAC AACTATGCAC CCAACCCAGA CAAGCACTGG 
ATCATGCGCT ACACGGGACC CATGAAGCCC ATTCACATGG AATTCACCAA CATGCTACAG 
CGCAAACGCC TGCAGACCCT CATGTCTGTG GACGACTCCA TGGAGACGAT CTATGACATG 
CTAGTGGAGA CGGGCGAGCT GGACAATACC TACATCGTGT ACACCGCCGA CCACGGCTAC 
CACATTGGCC AGTTTGGCCT GGTGAAGGGC AAGTCCATGC CCTATGAGTT TGACATCAGG 
GTCCCGTTCT ATGTGCGGGG CCCCAGCGTG GAAGCTGGCT CTCTGAACCC CCACATCGTC 
CTCAACATTG ACCTGGCCCC CACCATACTG GATATCGCTG GACTGGACAT CCCTGCAGAC 
ATGGACGGGA AGTCCATCCT CAAACTACTG GACTCAGAGC GGCCAGTGAA CCGGTTCCAC 
CTGAAAAAGA AGCTGAGGGT CTGGCGAGAC TCCTTCCTGG TGGAAAGAGG CAAACTGCTC 
CACAAGAGGG AGGGTGACAA AGTGAACGCC CAGGAGGAGA ACTTCCTGCC CAAGTATCAG 
CGTGTGAAGG ACCTGTGTCA AAGGGCTGAG TACCAGACAG CATGCGAGCA GCTAGGGCAG 
AAGTGGCAGT GTGTAGAGGA CGCTTCTGGG GCGCTGAAGC TGCACAAGTG TAAAGGCCCG 
GTGCGGTTCG GGGGCGGTGG TGACAGAGCC CTCTCCAACC TGGTGCCCAA GTACGACGGC 
CAAAGCAGCG AGGCCTGCAG CTGTGACGGC GGCGGCGGCG GAGGGGACTA CAAACTGGGC 
CTGGCTGGAC GCCGGAAGCT CTTTAAGAAA AAGTACAAGA CCAGCTATGC CCGGAACCGC 
TCCATCCGCT CTGTGGCCAT CGAGGTGGAT GGCGAGGTAT ACCACGTAGG CTTGGATAAC 
ATGCCGCTGC CCCGCAACCT CACCAAGCGT CACTGGCCAG GGGCCCCTGA AGACCAGGAT 
GACAAGGATG GTGGAAGTTT CAGTGGTACT GGTGGCCTTC CAGATTATTC TGCCCCCAAT 
CCCATTAAAG TGACCCATCG GTGCTACATC CTTGAGAATG ACACAGTCCA GTGTGACTTG 
GACCTGTACA AGTCCCTGCA GGCTTGGAAA GACCACAAAT TGCACATCGA CCATGAGATT 
GAAACCCTGC AGAACAAAAT TAAGAACCTT CGAGAAGTCA GGGGTCACCT GAAGAAGAAG 
CGGCCAGAAG AATGTGACTG TCACAAAGTC AGTTACCACA GCCAACACAA AGGCCGCCTC 
AAGCACAAGG GCTCCAGCCT GCACCCTTTC AGGAAGGGTC TGCAGGAGAA AGACAAGGTG 
TGGCTGTTGC GGGAGCAGAA ACGCAAGAAG AAACTGCGCA AGCTGCTGAA GCGACTGCAG 
AACAATGACA CGTGCAGCAT GCCGGGCCTC ACGTGCTTTA CTCACGACAA CCACCACTGG 
CAGACCGCGC CGCTCTGGAC GTTGGGACCC TTCTGCGCCT GCACCAGCGC CAACAATAAC 
ACGTACTGGT GCCTGCGGAC CATCAACGAG ACCCACAACT TCCTCTTCTG TGAATTCGCA 
ACTGGCTTCA TAGAATACTT TGACCTCAGT ACGGACCCCT ACCAGCTGAT GAACGCGGTC 
AACACACTGG ACAGGGACGT TCTCAACCAG CTGCACGTCC AGCTCATGGA GCTAAGGAGC 
TGCAAAGGCT ACAAGCAGTG TAACCCCCGG ACCCGCAATA TGGACCTGGG GCTTAGAGAC 
GGAGGAAGCT ATGAGCAATA CAGGCAGTTT CAGCGTCGAA AATGGCCAGA AATGAAGAGA 
CCCTCTTCCA AATCACTGGG ACAGCTATGG GAAGGTTGGG AAGGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006235658.1
CDS	247..2874
Translation	MAPPGLPLWLLSTALFSLLAGSSAFLSYPRLKGRFQRDRRNIRPNIILVLTDDQDVELGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYTNNENCSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYNGSYVPPGWKEWVGLLKNSRFYNYTLCRNGMKEKHGSDYSTDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQYSRLFPNASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQRKRLQTLMSVDDSMETIYDMLVETGELDNTYIVYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPSVEAGSLNPHIVLNIDLAPTILDIAGLDIPADMDGKSILKLLDSERPVNRFHLKKKLRVWRDSFLVERGKLLHKREGDKVNAQEENFLPKYQRVKDLCQRAEYQTACEQLGQKWQCVEDASGALKLHKCKGPVRFGGGGDRALSNLVPKYDGQSSEACSCDGGGGGGDYKLGLAGRRKLFKKKYKTSYARNRSIRSVAIEVDGEVYHVGLDNMPLPRNLTKRHWPGAPEDQDDKDGGSFSGTGGLPDYSAPNPIKVTHRCYILENDTVQCDLDLYKSLQAWKDHKLHIDHEIETLQNKIKNLREVRGHLKKKRPEECDCHKVSYHSQHKGRLKHKGSSLHPFRKGLQEKDKVWLLREQKRKKKLRKLLKRLQNNDTCSMPGLTCFTHDNHHWQTAPLWTLGPFCACTSANNNTYWCLRTINETHNFLFCEFATGFIEYFDLSTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLRDGGSYEQYRQFQRRKWPEMKRPSSKSLGQLWEGWEG

Target ORF information:

RefSeq Version	XM_006235596.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus sulfatase 2 (Sulf2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006235596.3

ORF Insert Sequence:

ATGGCACCCC CTGGCCTGCC ACTGTGGCTG CTGTCCACCG CTCTCTTCTC CCTTCTGGCT 
GGCAGCTCAG CCTTCCTCTC CTATCCCCGC CTGAAGGGTC GCTTCCAGAG GGACCGCAGG 
AATATCCGGC CCAACATCAT CTTGGTGCTC ACGGATGACC AGGACGTGGA GCTGGGCTCC 
ATGCAGGTGA TGAACAAGAC ACGACGTATC ATGGAGCAGG GCGGGGCACA CTTCATCAAC 
GCCTTCGTGA CTACACCTAT GTGCTGTCCC TCTCGCTCCT CCATCCTCAC CGGCAAGTAC 
GTCCACAATC ACAACACCTA CACCAACAAC GAGAACTGTT CCTCGCCCTC CTGGCAGGCA 
CAGCATGAGA GCCGAACCTT CGCCGTGTAC CTCAACAGCA CTGGCTACCG GACAGCTTTC 
TTCGGAAAAT ACCTCAATGA ATACAACGGC TCATATGTGC CGCCTGGCTG GAAGGAGTGG 
GTTGGACTCC TTAAGAACTC GCGTTTTTAT AACTACACAC TCTGCCGGAA TGGGATGAAG 
GAGAAGCATG GCTCTGACTA CTCCACGGAT TACCTCACAG ATCTCATCAC CAATGACAGT 
GTGAGCTTCT TCCGAACATC CAAGAAGATG TACCCACACA GACCTGTGCT CATGGTCATC 
AGCCACGCAG CTCCCCACGG CCCTGAGGAC TCAGCACCCC AGTACTCACG CCTCTTCCCC 
AATGCATCCC AGCACATCAC ACCGAGTTAC AACTATGCAC CCAACCCAGA CAAGCACTGG 
ATCATGCGCT ACACGGGACC CATGAAGCCC ATTCACATGG AATTCACCAA CATGCTACAG 
CGCAAACGCC TGCAGACCCT CATGTCTGTG GACGACTCCA TGGAGACGAT CTATGACATG 
CTAGTGGAGA CGGGCGAGCT GGACAATACC TACATCGTGT ACACCGCCGA CCACGGCTAC 
CACATTGGCC AGTTTGGCCT GGTGAAGGGC AAGTCCATGC CCTATGAGTT TGACATCAGG 
GTCCCGTTCT ATGTGCGGGG CCCCAGCGTG GAAGCTGGCT CTCTGAACCC CCACATCGTC 
CTCAACATTG ACCTGGCCCC CACCATACTG GATATCGCTG GACTGGACAT CCCTGCAGAC 
ATGGACGGGA AGTCCATCCT CAAACTACTG GACTCAGAGC GGCCAGTGAA CCGGTTCCAC 
CTGAAAAAGA AGCTGAGGGT CTGGCGAGAC TCCTTCCTGG TGGAAAGAGG CAAACTGCTC 
CACAAGAGGG AGGGTGACAA AGTGAACGCC CAGGAGGAGA ACTTCCTGCC CAAGTATCAG 
CGTGTGAAGG ACCTGTGTCA AAGGGCTGAG TACCAGACAG CATGCGAGCA GCTAGGGCAG 
AAGTGGCAGT GTGTAGAGGA CGCTTCTGGG GCGCTGAAGC TGCACAAGTG TAAAGGCCCG 
GTGCGGTTCG GGGGCGGTGG TGACAGAGCC CTCTCCAACC TGGTGCCCAA GTACGACGGC 
CAAAGCAGCG AGGCCTGCAG CTGTGACGGC GGCGGCGGCG GAGGGGACTA CAAACTGGGC 
CTGGCTGGAC GCCGGAAGCT CTTTAAGAAA AAGTACAAGA CCAGCTATGC CCGGAACCGC 
TCCATCCGCT CTGTGGCCAT CGAGGTGGAT GGCGAGGTAT ACCACGTAGG CTTGGATAAC 
ATGCCGCTGC CCCGCAACCT CACCAAGCGT CACTGGCCAG GGGCCCCTGA AGACCAGGAT 
GACAAGGATG GTGGAAGTTT CAGTGGTACT GGTGGCCTTC CAGATTATTC TGCCCCCAAT 
CCCATTAAAG TGACCCATCG GTGCTACATC CTTGAGAATG ACACAGTCCA GTGTGACTTG 
GACCTGTACA AGTCCCTGCA GGCTTGGAAA GACCACAAAT TGCACATCGA CCATGAGATT 
GAAACCCTGC AGAACAAAAT TAAGAACCTT CGAGAAGTCA GGGGTCACCT GAAGAAGAAG 
CGGCCAGAAG AATGTGACTG TCACAAAGTC AGTTACCACA GCCAACACAA AGGCCGCCTC 
AAGCACAAGG GCTCCAGCCT GCACCCTTTC AGGAAGGGTC TGCAGGAGAA AGACAAGGTG 
TGGCTGTTGC GGGAGCAGAA ACGCAAGAAG AAACTGCGCA AGCTGCTGAA GCGACTGCAG 
AACAATGACA CGTGCAGCAT GCCGGGCCTC ACGTGCTTTA CTCACGACAA CCACCACTGG 
CAGACCGCGC CGCTCTGGAC GTTGGGACCC TTCTGCGCCT GCACCAGCGC CAACAATAAC 
ACGTACTGGT GCCTGCGGAC CATCAACGAG ACCCACAACT TCCTCTTCTG TGAATTCGCA 
ACTGGCTTCA TAGAATACTT TGACCTCAGT ACGGACCCCT ACCAGCTGAT GAACGCGGTC 
AACACACTGG ACAGGGACGT TCTCAACCAG CTGCACGTCC AGCTCATGGA GCTAAGGAGC 
TGCAAAGGCT ACAAGCAGTG TAACCCCCGG ACCCGCAATA TGGACCTGGG GCTTAGAGAC 
GGAGGAAGCT ATGAGCAATA CAGGCAGTTT CAGCGTCGAA AATGGCCAGA AATGAAGAGA 
CCCTCTTCCA AATCACTGGG ACAGCTATGG GAAGGTTGGG AAGGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression of Sulf1 and Sulf2 in cartilage, bone and endochondral fracture healing.
Histochemistry and cell biology145(1)67-79(2016 Jan)
Zaman G,Staines KA,Farquharson C,Newton PT,Dudhia J,Chenu C,Pitsillides AA,Dhoot GK

Sulf1 and Sulf2 expression in the nervous system and its role in limiting neurite outgrowth in vitro.
Experimental neurology263150-60(2015 Jan)
Joy MT,Vrbova G,Dhoot GK,Anderson PN

Activation of the transcription factor GLI1 by WNT signaling underlies the role of SULFATASE 2 as a regulator of tissue regeneration.
The Journal of biological chemistry288(29)21389-98(2013 Jul)
Nakamura I,Fernandez-Barrena MG,Ortiz-Ruiz MC,Almada LL,Hu C,Elsawa SF,Mills LD,Romecin PA,Gulaid KH,Moser CD,Han JJ,Vrabel A,Hanse EA,Akogyeram NA,Albrecht JH,Monga SP,Sanderson SO,Prieto J,Roberts LR,Fernandez-Zapico ME

WT1-dependent sulfatase expression maintains the normal glomerular filtration barrier.
Journal of the American Society of Nephrology : JASN22(7)1286-96(2011 Jul)
Schumacher VA,Schl?tzer-Schrehardt U,Karumanchi SA,Shi X,Zaia J,Jeruschke S,Zhang D,Pavenst?dt H,Pavenstaedt H,Drenckhan A,Amann K,Ng C,Hartwig S,Ng KH,Ho J,Kreidberg JA,Taglienti M,Royer-Pokora B,Ai X

Extracellular sulfatases support cartilage homeostasis by regulating BMP and FGF signaling pathways.
Proceedings of the National Academy of Sciences of the United States of America107(22)10202-7(2010 Jun)
Otsuki S,Hanson SR,Miyaki S,Grogan SP,Kinoshita M,Asahara H,Wong CH,Lotz MK

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Sulf2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報