Kif5c cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Kif5c
Entrez Gene ID	311024
Full Name	kinesin family member 5C
General protein information	Preferred Names kinesin family member 5C Names kinesin heavy chain isoform 5C kinesin heavy chain kinesin heavy chain neuron-specific 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q12

mRNA and Protein(s)

mRNA	Protein	Name
NM_001107730.1	NP_001101200.1	kinesin heavy chain isoform 5C
XM_008761745.2	XP_008759967.1	kinesin heavy chain isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	KIF5C	NP_001069595.2
Rattus norvegicus (Norway rat)	Kif5c	NP_001101200.1
Canis lupus familiaris (dog)	KIF5C	XP_533351.3
Pan troglodytes (chimpanzee)	KIF5C	XP_525938.3
	KIF5C	XP_001082054.2
Mus musculus (house mouse)	Kif5c	NP_032475.2
Gallus gallus (chicken)	KIF5C	XP_422155.2
Danio rerio (zebrafish)	kif5c	NP_001116747.1
Xenopus tropicalis (tropical clawed frog)	kif5c	XP_002935337.2
Homo sapiens (human)	KIF5C	NP_004513.1

Gene Ontology
Bibliography

Related articles in PubMed

The Motor KIF5C Links the Requirements of Stable Microtubules and IGF-1 Receptor Membrane Insertion for Neuronal Polarization.
Oksdath M, Guil AFN, Grassi D, Sosa LJ, Quiroga S
Molecular neurobiology54(8)6085-6096(2017 Oct)

SKIP controls lysosome positioning using a composite kinesin-1 heavy and light chain-binding domain.
Sanger A, Yip YY, Randall TS, Pernigo S, Steiner RA, Dodding MP
Journal of cell science130(9)1637-1651(2017 May)

Kif5 regulates mitochondrial movement, morphology, function and neuronal survival.
Iworima DG, Pasqualotto BA, Rintoul GL
Molecular and cellular neurosciences7222-33(2016 Apr)

Regulation of mitochondrial transport in neurons.
Lin MY, Sheng ZH
Experimental cell research334(1)35-44(2015 May)

Effects of ?-tubulin K40 acetylation and detyrosination on kinesin-1 motility in a purified system.
Kaul N, Soppina V, Verhey KJ
Biophysical journal106(12)2636-43(2014 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Kif5 plays a role in regulating mitochondrial morphology. Kif5c disruption was neuroprotective during excitotoxicity but not H2O2 toxicity.
Title: Kif5 regulates mitochondrial movement, morphology, function and neuronal survival.

Lysine 40 acetylation of alpha-tubulin does not result in significant changes in kinesin-1's landing rate or motility parameters.
Title: Effects of ?-tubulin K40 acetylation and detyrosination on kinesin-1 motility in a purified system.

motility of Kinesin-1, preferential translocation of Kinesin-1 on axonal microtubules in polarized neurons is not determined by acetylation alone but probably specified by a combination of tubulin modifications
Title: Posttranslational modifications of tubulin and the polarized transport of kinesin-1 in neurons.

binding of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function
Title: Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.

The following Kif5c gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kif5c cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa05774	NM_001107730.1 Latest version!	Rattus norvegicus kinesin family member 5C (Kif5c), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
ORa46923	XM_008761745.2 Latest version!	Rattus norvegicus kinesin family member 5C (Kif5c), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Kif5c ( NM_001107730.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101200.1 Rattus norvegicus kinesin family member 5C (Kif5c), mRNA.

Price & Availability↑

CloneID	ORa05774
Clone ID Related Accession (Same CDS sequence)	NM_001107730.1
Accession Version	NM_001107730.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2868bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Rattus norvegicus(Norway rat)
Product	kinesin heavy chain isoform 5C
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473983.2. On or before Oct 4, 2007 this sequence version replaced XM_241981.4, XM_001064328.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCGGATC CAGCCGAATG CAGCATCAAA GTGATGTGCC GGTTCCGGCC CCTCAACGAA 
GCTGAGATCC TCCGCGGGGA CAAATTCATC CCCAAATTCA AAGGCGAGGA GACGGTGGTG 
ATCGGGCAAG GGAAGCCGTA TGTCTTTGAC CGAGTTCTGC CGCCCAACAC AACCCAGGAG 
CAGGTCTACA ATGCCTGTGC GAAGCAGATT GTCAAAGATG TCCTCGAGGG TTACAATGGG 
ACAATTTTTG CATACGGGCA GACTTCATCA GGAAAAACTC ATACCATGGA GGGGAAGCTG 
CACGATCCTC AGCTTATGGG TATCATACCC AGGATCGCAC ACGATATTTT CGATCACATC 
TATTCCATGG ATGAGAACTT GGAGTTTCAT ATCAAGGTTT CCTATTTTGA GATCTACTTG 
GACAAAATAA GGGACTTGCT TGACGTGTCC AAGACCAACT TGGCTGTTCA TGAAGACAAA 
AACAGAGTCC CCTATGTAAA GGGGTGCACC GAGAGGTTTG TGTCAAGCCC GGAGGAGGTC 
ATGGATGTGA TCGATGAGGG CAAAGCAAAC CGACATGTGG CTGTGACAAA CATGAACGAA 
CACAGCTCCA GGAGTCACAG TATCTTCCTG ATTAACATTA AACAAGAGAA TGTGGAGACT 
GAAAAAAAAC TCAGCGGGAA GCTGTATTTG GTTGATTTGG CTGGGAGTGA AAAGGTCAGC 
AAAACTGGTG CCGAGGGAGC TGTTCTTGAT GAAGCTAAAA ATATCAACAA GTCTTTGTCT 
GCTCTTGGAA ATGTGATCTC TGCCTTGGCA GAAGGGACAA AAACACATGT GCCATACCGG 
GACAGCAAGA TGACTCGGAT TCTCCAGGAC TCTCTGGGTG GGAACTGCAG GACCACCATT 
GTCATTTGCT GTTCTCCTTC AGTCTTCAAT GAGGCTGAGA CCAAGTCCAC GCTGATGTTT 
GGACAGAGAG CAAAGACCAT CAAGAATACA GTCTCTGTGA ACTTGGAACT AACAGCAGAA 
GAATGGAAGA AGAAATATGA AAAAGAGAAA GAGAAGAATA AGGCCCTGAA GAGTGTCATC 
CAGCATCTGG AGGTGGAGCT GAACAGGTGG AGGAACGGGG AAGCTGTGCC TGAGGATGAA 
CAGATCAGTG CCAAGGACCA GAAGAACCTG GAGCCCTGCG ACAACACACC CATCATAGAC 
AACATCACAC CTGTGGTTGA CGGCATCTCT GCTGAGAAAG AGAAGTATGA CGAGGAAATC 
ACCAGTCTGT ACCGACAGCT GGATGACAAG GACGATGAAA TTAACCAGCA GAGCCAGCTG 
GCTGAAAAGC TGAAGCAACA GATGTTGGAT CAGGACGAGC TTCTAGCTTC CACCAGAAGG 
GACTACGAGA AAATCCAGGA GGAGCTGACC CGCCTCCAGA TTGAAAACGA GGCGGCTAAA 
GACGAGGTGA AGGAGGTCCT CCAGGCCCTG GAGGAGCTGG CTGTCAATTA CGACCAGAAG 
TCACAGGAAG TGGAGGACAA GACCCGGGCC AACGAGCAAC TGACCGATGA GCTGGCCCAG 
AAAACGACGA CACTGACAAC CACCCAGCGG GAGCTGAGTC AGCTACAGGA GCTTAGCAAC 
CACCAGAAGA AGAGGGCCAC GGAGATCCTG AACCTGCTTC TCAAGGATCT GGGCGAGATA 
GGTGGAATTA TCGGCACCAA CGATGTGAAG ACCCTGGCAG ATGTGAATGG AGTCATCGAA 
GAGGAGTTCA CCATGGCCCG CCTGTACATT AGCAAGATGA AGTCGGAGGT CAAGTCTCTC 
GTGAACCGCA GCAAGCAGCT GGAGAGCGCC CAGACGGACT CCAACAGGAA GATGAATGCC 
AGCGAGCGGG AGCTGGCAGC TTGCCAGTTG CTTATCTCGC AGCATGAAGC CAAGATCAAG 
TCTCTGACAG ACTACATGCA GAACATGGAA CAGAAGAGGC GGCAGCTGGA AGAGTCGCAG 
GACTCCCTCA GCGAGGAGCT GGCCAAGCTC CGGGCCCAAG AAAAAATGCA CGAAGTCAGT 
TTCCAAGATA AGGAAAAGGA GCACCTGACG AGGCTGCAGG ATGCTGAGGA AGTGAAGAAG 
GCTCTGGAGC AGCAGATGGA GAGTCACCGG GAAGCGCACC AAAAGCAGCT GTCCAGACTT 
CGTGATGAGA TTGAGGAGAA GCAGAGAATC ATTGATGAGA TTCGGGATTT GAATCAGAAG 
CTGCAACTGG AACAGGAGAG GCTCAGCTCT GATTATAACA AGCTGAAAAT AGAGGACCAG 
GAGAGAGAAG TGAAGCTGGA GAAGCTCCTA TTGCTCAATG ACAAAAGAGA GCAAGCCAGG 
GAGGACCTCA AGGGACTGGA AGAGACTGTG TCCAGAGAAC TCCAGACTCT TCACAACCTG 
CGCAAACTCT TCGTCCAGGA CTTGACCACC CGGGTGAAAA AGAGTGTGGA GCTGGACAGC 
GACGATGGAG GGGGTAGTGC CGCCCAGAAG CAGAAGATCT CCTTCCTGGA GAACAACCTG 
GAGCAGCTTA CCAAGGTGCA CAAGCAGCTG GTCCGGGACA ATGCGGATTT GCGCTGTGAA 
CTCCCCAAGC TGGAGAAGAG GCTCCGTGCT ACTGCAGAGC GTGTCAAGGC CTTGGAGAGT 
GCGCTCAAAG AGGCCAAGGA GAATGCCATG AGGGACCGAA AGCGCTACCA GCAGGAAGTG 
GATCGCATCA AGGAGGCTGT GCGGGCCAAG AACATGGCCA GGAGGGCACA TTCGGCTCAG 
ATCGCCAAGC CCATCCGCCC AGGACACTAT CCTGCATCAT CTCCAACAGC CGTCCATGCC 
GTCCGGGGAG GAGGTGGATC TTCAAACTCC ACTCACTACC AGAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101200.1
CDS	352..3219
Translation	MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKALKSVIQHLEVELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNITPVVDGISAEKEKYDEEITSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQTDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEVKKALEQQMESHREAHQKQLSRLRDEIEEKQRIIDEIRDLNQKLQLEQERLSSDYNKLKIEDQEREVKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDSDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQEVDRIKEAVRAKNMARRAHSAQIAKPIRPGHYPASSPTAVHAVRGGGGSSNSTHYQK

Target ORF information:

RefSeq Version	NM_001107730.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus kinesin family member 5C (Kif5c), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001107730.1

ORF Insert Sequence:

ATGGCGGATC CAGCCGAATG CAGCATCAAA GTGATGTGCC GGTTCCGGCC CCTCAACGAA 
GCTGAGATCC TCCGCGGGGA CAAATTCATC CCCAAATTCA AAGGCGAGGA GACGGTGGTG 
ATCGGGCAAG GGAAGCCGTA TGTCTTTGAC CGAGTTCTGC CGCCCAACAC AACCCAGGAG 
CAGGTCTACA ATGCCTGTGC GAAGCAGATT GTCAAAGATG TCCTCGAGGG TTACAATGGG 
ACAATTTTTG CATACGGGCA GACTTCATCA GGAAAAACTC ATACCATGGA GGGGAAGCTG 
CACGATCCTC AGCTTATGGG TATCATACCC AGGATCGCAC ACGATATTTT CGATCACATC 
TATTCCATGG ATGAGAACTT GGAGTTTCAT ATCAAGGTTT CCTATTTTGA GATCTACTTG 
GACAAAATAA GGGACTTGCT TGACGTGTCC AAGACCAACT TGGCTGTTCA TGAAGACAAA 
AACAGAGTCC CCTATGTAAA GGGGTGCACC GAGAGGTTTG TGTCAAGCCC GGAGGAGGTC 
ATGGATGTGA TCGATGAGGG CAAAGCAAAC CGACATGTGG CTGTGACAAA CATGAACGAA 
CACAGCTCCA GGAGTCACAG TATCTTCCTG ATTAACATTA AACAAGAGAA TGTGGAGACT 
GAAAAAAAAC TCAGCGGGAA GCTGTATTTG GTTGATTTGG CTGGGAGTGA AAAGGTCAGC 
AAAACTGGTG CCGAGGGAGC TGTTCTTGAT GAAGCTAAAA ATATCAACAA GTCTTTGTCT 
GCTCTTGGAA ATGTGATCTC TGCCTTGGCA GAAGGGACAA AAACACATGT GCCATACCGG 
GACAGCAAGA TGACTCGGAT TCTCCAGGAC TCTCTGGGTG GGAACTGCAG GACCACCATT 
GTCATTTGCT GTTCTCCTTC AGTCTTCAAT GAGGCTGAGA CCAAGTCCAC GCTGATGTTT 
GGACAGAGAG CAAAGACCAT CAAGAATACA GTCTCTGTGA ACTTGGAACT AACAGCAGAA 
GAATGGAAGA AGAAATATGA AAAAGAGAAA GAGAAGAATA AGGCCCTGAA GAGTGTCATC 
CAGCATCTGG AGGTGGAGCT GAACAGGTGG AGGAACGGGG AAGCTGTGCC TGAGGATGAA 
CAGATCAGTG CCAAGGACCA GAAGAACCTG GAGCCCTGCG ACAACACACC CATCATAGAC 
AACATCACAC CTGTGGTTGA CGGCATCTCT GCTGAGAAAG AGAAGTATGA CGAGGAAATC 
ACCAGTCTGT ACCGACAGCT GGATGACAAG GACGATGAAA TTAACCAGCA GAGCCAGCTG 
GCTGAAAAGC TGAAGCAACA GATGTTGGAT CAGGACGAGC TTCTAGCTTC CACCAGAAGG 
GACTACGAGA AAATCCAGGA GGAGCTGACC CGCCTCCAGA TTGAAAACGA GGCGGCTAAA 
GACGAGGTGA AGGAGGTCCT CCAGGCCCTG GAGGAGCTGG CTGTCAATTA CGACCAGAAG 
TCACAGGAAG TGGAGGACAA GACCCGGGCC AACGAGCAAC TGACCGATGA GCTGGCCCAG 
AAAACGACGA CACTGACAAC CACCCAGCGG GAGCTGAGTC AGCTACAGGA GCTTAGCAAC 
CACCAGAAGA AGAGGGCCAC GGAGATCCTG AACCTGCTTC TCAAGGATCT GGGCGAGATA 
GGTGGAATTA TCGGCACCAA CGATGTGAAG ACCCTGGCAG ATGTGAATGG AGTCATCGAA 
GAGGAGTTCA CCATGGCCCG CCTGTACATT AGCAAGATGA AGTCGGAGGT CAAGTCTCTC 
GTGAACCGCA GCAAGCAGCT GGAGAGCGCC CAGACGGACT CCAACAGGAA GATGAATGCC 
AGCGAGCGGG AGCTGGCAGC TTGCCAGTTG CTTATCTCGC AGCATGAAGC CAAGATCAAG 
TCTCTGACAG ACTACATGCA GAACATGGAA CAGAAGAGGC GGCAGCTGGA AGAGTCGCAG 
GACTCCCTCA GCGAGGAGCT GGCCAAGCTC CGGGCCCAAG AAAAAATGCA CGAAGTCAGT 
TTCCAAGATA AGGAAAAGGA GCACCTGACG AGGCTGCAGG ATGCTGAGGA AGTGAAGAAG 
GCTCTGGAGC AGCAGATGGA GAGTCACCGG GAAGCGCACC AAAAGCAGCT GTCCAGACTT 
CGTGATGAGA TTGAGGAGAA GCAGAGAATC ATTGATGAGA TTCGGGATTT GAATCAGAAG 
CTGCAACTGG AACAGGAGAG GCTCAGCTCT GATTATAACA AGCTGAAAAT AGAGGACCAG 
GAGAGAGAAG TGAAGCTGGA GAAGCTCCTA TTGCTCAATG ACAAAAGAGA GCAAGCCAGG 
GAGGACCTCA AGGGACTGGA AGAGACTGTG TCCAGAGAAC TCCAGACTCT TCACAACCTG 
CGCAAACTCT TCGTCCAGGA CTTGACCACC CGGGTGAAAA AGAGTGTGGA GCTGGACAGC 
GACGATGGAG GGGGTAGTGC CGCCCAGAAG CAGAAGATCT CCTTCCTGGA GAACAACCTG 
GAGCAGCTTA CCAAGGTGCA CAAGCAGCTG GTCCGGGACA ATGCGGATTT GCGCTGTGAA 
CTCCCCAAGC TGGAGAAGAG GCTCCGTGCT ACTGCAGAGC GTGTCAAGGC CTTGGAGAGT 
GCGCTCAAAG AGGCCAAGGA GAATGCCATG AGGGACCGAA AGCGCTACCA GCAGGAAGTG 
GATCGCATCA AGGAGGCTGT GCGGGCCAAG AACATGGCCA GGAGGGCACA TTCGGCTCAG 
ATCGCCAAGC CCATCCGCCC AGGACACTAT CCTGCATCAT CTCCAACAGC CGTCCATGCC 
GTCCGGGGAG GAGGTGGATC TTCAAACTCC ACTCACTACC AGAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Kif5c ( XM_008761745.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008759967.1 Rattus norvegicus kinesin family member 5C (Kif5c), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa46923
Clone ID Related Accession (Same CDS sequence)	XM_008761745.2
Accession Version	XM_008761745.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2868bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	kinesin heavy chain isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008761745.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGATC CAGCCGAATG CAGCATCAAA GTGATGTGCC GGTTCCGGCC CCTCAACGAA 
GCTGAGATCC TCCGCGGGGA CAAATTCATC CCCAAATTCA AAGGCGAGGA GACGGTGGTG 
ATCGGGCAAG GGAAGCCGTA TGTCTTTGAC CGAGTTCTGC CGCCCAACAC AACCCAGGAG 
CAGGTCTACA ATGCCTGTGC GAAGCAGATT GTCAAAGATG TCCTCGAGGG TTACAATGGG 
ACAATTTTTG CATACGGGCA GACTTCATCA GGAAAAACTC ATACCATGGA GGGGAAGCTG 
CACGATCCTC AGCTTATGGG TATCATACCC AGGATCGCAC ACGATATTTT CGATCACATC 
TATTCCATGG ATGAGAACTT GGAGTTTCAT ATCAAGGTTT CCTATTTTGA GATCTACTTG 
GACAAAATAA GGGACTTGCT TGACGTGTCC AAGACCAACT TGGCTGTTCA TGAAGACAAA 
ACAGAAGTCC CTTTCTTGCA GGGGTGCACC GAGAGGTTTG TGTCAAGCCC GGAGGAGGTC 
ATGGATGTGA TCGATGAGGG CAAAGCAAAC CGACATGTGG CTGTGACAAA CATGAACGAA 
CACAGCTCCA GGAGTCACAG TATCTTCCTG ATTAACATTA AACAAGAGAA TGTGGAGACT 
GAAAAAAAAC TCAGCGGGAA GCTGTATTTG GTTGATTTGG CTGGGAGTGA AAAGGTCAGC 
AAAACTGGTG CCGAGGGAGC TGTTCTTGAT GAAGCTAAAA ATATCAACAA GTCTTTGTCT 
GCTCTTGGAA ATGTGATCTC TGCCTTGGCA GAAGGGACAA AAACACATGT GCCATACCGG 
GACAGCAAGA TGACTCGGAT TCTCCAGGAC TCTCTGGGTG GGAACTGCAG GACCACCATT 
GTCATTTGCT GTTCTCCTTC AGTCTTCAAT GAGGCTGAGA CCAAGTCCAC GCTGATGTTT 
GGACAGAGAG CAAAGACCAT CAAGAATACA GTCTCTGTGA ACTTGGAACT AACAGCAGAA 
GAATGGAAGA AGAAATATGA AAAAGAGAAA GAGAAGAATA AGGCCCTGAA GAGTGTCATC 
CAGCATCTGG AGGTGGAGCT GAACAGGTGG AGGAACGGGG AAGCTGTGCC TGAGGATGAA 
CAGATCAGTG CCAAGGACCA GAAGAACCTG GAGCCCTGCG ACAACACACC CATCATAGAC 
AACATCACAC CTGTGGTTGA CGGCATCTCT GCTGAGAAAG AGAAGTATGA CGAGGAAATC 
ACCAGTCTGT ACCGACAGCT GGATGACAAG GACGATGAAA TTAACCAGCA GAGCCAGCTG 
GCTGAAAAGC TGAAGCAACA GATGTTGGAT CAGGACGAGC TTCTAGCTTC CACCAGAAGG 
GACTACGAGA AAATCCAGGA GGAGCTGACC CGCCTCCAGA TTGAAAACGA GGCGGCTAAA 
GACGAGGTGA AGGAGGTCCT CCAGGCCCTG GAGGAGCTGG CTGTCAATTA CGACCAGAAG 
TCACAGGAAG TGGAGGACAA GACCCGGGCC AACGAGCAAC TGACCGATGA GCTGGCCCAG 
AAAACGACGA CACTGACAAC CACCCAGCGG GAGCTGAGTC AGCTACAGGA GCTTAGCAAC 
CACCAGAAGA AGAGGGCCAC GGAGATCCTG AACCTGCTTC TCAAGGATCT GGGCGAGATA 
GGTGGAATTA TCGGCACCAA CGATGTGAAG ACCCTGGCAG ATGTGAATGG AGTCATCGAA 
GAGGAGTTCA CCATGGCCCG CCTGTACATT AGCAAGATGA AGTCGGAGGT CAAGTCTCTC 
GTGAACCGCA GCAAGCAGCT GGAGAGCGCC CAGACGGACT CCAACAGGAA GATGAATGCC 
AGCGAGCGGG AGCTGGCAGC TTGCCAGTTG CTTATCTCGC AGCATGAAGC CAAGATCAAG 
TCTCTGACAG ACTACATGCA GAACATGGAA CAGAAGAGGC GGCAGCTGGA AGAGTCGCAG 
GACTCCCTCA GCGAGGAGCT GGCCAAGCTC CGGGCCCAAG AAAAAATGCA CGAAGTCAGT 
TTCCAAGATA AGGAAAAGGA GCACCTGACG AGGCTGCAGG ATGCTGAGGA AGTGAAGAAG 
GCTCTGGAGC AGCAGATGGA GAGTCACCGG GAAGCGCACC AAAAGCAGCT GTCCAGACTT 
CGTGATGAGA TTGAGGAGAA GCAGAGAATC ATTGATGAGA TTCGGGATTT GAATCAGAAG 
CTGCAACTGG AACAGGAGAG GCTCAGCTCT GATTATAACA AGCTGAAAAT AGAGGACCAG 
GAGAGAGAAG TGAAGCTGGA GAAGCTCCTA TTGCTCAATG ACAAAAGAGA GCAAGCCAGG 
GAGGACCTCA AGGGACTGGA AGAGACTGTG TCCAGAGAAC TCCAGACTCT TCACAACCTG 
CGCAAACTCT TCGTCCAGGA CTTGACCACC CGGGTGAAAA AGAGTGTGGA GCTGGACAGC 
GACGATGGAG GGGGTAGTGC CGCCCAGAAG CAGAAGATCT CCTTCCTGGA GAACAACCTG 
GAGCAGCTTA CCAAGGTGCA CAAGCAGCTG GTCCGGGACA ATGCGGATTT GCGCTGTGAA 
CTCCCCAAGC TGGAGAAGAG GCTCCGTGCT ACTGCAGAGC GTGTCAAGGC CTTGGAGAGT 
GCGCTCAAAG AGGCCAAGGA GAATGCCATG AGGGACCGAA AGCGCTACCA GCAGGAAGTG 
GATCGCATCA AGGAGGCTGT GCGGGCCAAG AACATGGCCA GGAGGGCACA TTCGGCTCAG 
ATCGCCAAGC CCATCCGCCC AGGACACTAT CCTGCATCAT CTCCAACAGC CGTCCATGCC 
GTCCGGGGAG GAGGTGGATC TTCAAACTCC ACTCACTACC AGAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008759967.1
CDS	382..3249
Translation	MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKTEVPFLQGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKALKSVIQHLEVELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNITPVVDGISAEKEKYDEEITSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQTDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEVKKALEQQMESHREAHQKQLSRLRDEIEEKQRIIDEIRDLNQKLQLEQERLSSDYNKLKIEDQEREVKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDSDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQEVDRIKEAVRAKNMARRAHSAQIAKPIRPGHYPASSPTAVHAVRGGGGSSNSTHYQK

Target ORF information:

RefSeq Version	XM_008761745.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus kinesin family member 5C (Kif5c), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008761745.2

ORF Insert Sequence:

ATGGCGGATC CAGCCGAATG CAGCATCAAA GTGATGTGCC GGTTCCGGCC CCTCAACGAA 
GCTGAGATCC TCCGCGGGGA CAAATTCATC CCCAAATTCA AAGGCGAGGA GACGGTGGTG 
ATCGGGCAAG GGAAGCCGTA TGTCTTTGAC CGAGTTCTGC CGCCCAACAC AACCCAGGAG 
CAGGTCTACA ATGCCTGTGC GAAGCAGATT GTCAAAGATG TCCTCGAGGG TTACAATGGG 
ACAATTTTTG CATACGGGCA GACTTCATCA GGAAAAACTC ATACCATGGA GGGGAAGCTG 
CACGATCCTC AGCTTATGGG TATCATACCC AGGATCGCAC ACGATATTTT CGATCACATC 
TATTCCATGG ATGAGAACTT GGAGTTTCAT ATCAAGGTTT CCTATTTTGA GATCTACTTG 
GACAAAATAA GGGACTTGCT TGACGTGTCC AAGACCAACT TGGCTGTTCA TGAAGACAAA 
ACAGAAGTCC CTTTCTTGCA GGGGTGCACC GAGAGGTTTG TGTCAAGCCC GGAGGAGGTC 
ATGGATGTGA TCGATGAGGG CAAAGCAAAC CGACATGTGG CTGTGACAAA CATGAACGAA 
CACAGCTCCA GGAGTCACAG TATCTTCCTG ATTAACATTA AACAAGAGAA TGTGGAGACT 
GAAAAAAAAC TCAGCGGGAA GCTGTATTTG GTTGATTTGG CTGGGAGTGA AAAGGTCAGC 
AAAACTGGTG CCGAGGGAGC TGTTCTTGAT GAAGCTAAAA ATATCAACAA GTCTTTGTCT 
GCTCTTGGAA ATGTGATCTC TGCCTTGGCA GAAGGGACAA AAACACATGT GCCATACCGG 
GACAGCAAGA TGACTCGGAT TCTCCAGGAC TCTCTGGGTG GGAACTGCAG GACCACCATT 
GTCATTTGCT GTTCTCCTTC AGTCTTCAAT GAGGCTGAGA CCAAGTCCAC GCTGATGTTT 
GGACAGAGAG CAAAGACCAT CAAGAATACA GTCTCTGTGA ACTTGGAACT AACAGCAGAA 
GAATGGAAGA AGAAATATGA AAAAGAGAAA GAGAAGAATA AGGCCCTGAA GAGTGTCATC 
CAGCATCTGG AGGTGGAGCT GAACAGGTGG AGGAACGGGG AAGCTGTGCC TGAGGATGAA 
CAGATCAGTG CCAAGGACCA GAAGAACCTG GAGCCCTGCG ACAACACACC CATCATAGAC 
AACATCACAC CTGTGGTTGA CGGCATCTCT GCTGAGAAAG AGAAGTATGA CGAGGAAATC 
ACCAGTCTGT ACCGACAGCT GGATGACAAG GACGATGAAA TTAACCAGCA GAGCCAGCTG 
GCTGAAAAGC TGAAGCAACA GATGTTGGAT CAGGACGAGC TTCTAGCTTC CACCAGAAGG 
GACTACGAGA AAATCCAGGA GGAGCTGACC CGCCTCCAGA TTGAAAACGA GGCGGCTAAA 
GACGAGGTGA AGGAGGTCCT CCAGGCCCTG GAGGAGCTGG CTGTCAATTA CGACCAGAAG 
TCACAGGAAG TGGAGGACAA GACCCGGGCC AACGAGCAAC TGACCGATGA GCTGGCCCAG 
AAAACGACGA CACTGACAAC CACCCAGCGG GAGCTGAGTC AGCTACAGGA GCTTAGCAAC 
CACCAGAAGA AGAGGGCCAC GGAGATCCTG AACCTGCTTC TCAAGGATCT GGGCGAGATA 
GGTGGAATTA TCGGCACCAA CGATGTGAAG ACCCTGGCAG ATGTGAATGG AGTCATCGAA 
GAGGAGTTCA CCATGGCCCG CCTGTACATT AGCAAGATGA AGTCGGAGGT CAAGTCTCTC 
GTGAACCGCA GCAAGCAGCT GGAGAGCGCC CAGACGGACT CCAACAGGAA GATGAATGCC 
AGCGAGCGGG AGCTGGCAGC TTGCCAGTTG CTTATCTCGC AGCATGAAGC CAAGATCAAG 
TCTCTGACAG ACTACATGCA GAACATGGAA CAGAAGAGGC GGCAGCTGGA AGAGTCGCAG 
GACTCCCTCA GCGAGGAGCT GGCCAAGCTC CGGGCCCAAG AAAAAATGCA CGAAGTCAGT 
TTCCAAGATA AGGAAAAGGA GCACCTGACG AGGCTGCAGG ATGCTGAGGA AGTGAAGAAG 
GCTCTGGAGC AGCAGATGGA GAGTCACCGG GAAGCGCACC AAAAGCAGCT GTCCAGACTT 
CGTGATGAGA TTGAGGAGAA GCAGAGAATC ATTGATGAGA TTCGGGATTT GAATCAGAAG 
CTGCAACTGG AACAGGAGAG GCTCAGCTCT GATTATAACA AGCTGAAAAT AGAGGACCAG 
GAGAGAGAAG TGAAGCTGGA GAAGCTCCTA TTGCTCAATG ACAAAAGAGA GCAAGCCAGG 
GAGGACCTCA AGGGACTGGA AGAGACTGTG TCCAGAGAAC TCCAGACTCT TCACAACCTG 
CGCAAACTCT TCGTCCAGGA CTTGACCACC CGGGTGAAAA AGAGTGTGGA GCTGGACAGC 
GACGATGGAG GGGGTAGTGC CGCCCAGAAG CAGAAGATCT CCTTCCTGGA GAACAACCTG 
GAGCAGCTTA CCAAGGTGCA CAAGCAGCTG GTCCGGGACA ATGCGGATTT GCGCTGTGAA 
CTCCCCAAGC TGGAGAAGAG GCTCCGTGCT ACTGCAGAGC GTGTCAAGGC CTTGGAGAGT 
GCGCTCAAAG AGGCCAAGGA GAATGCCATG AGGGACCGAA AGCGCTACCA GCAGGAAGTG 
GATCGCATCA AGGAGGCTGT GCGGGCCAAG AACATGGCCA GGAGGGCACA TTCGGCTCAG 
ATCGCCAAGC CCATCCGCCC AGGACACTAT CCTGCATCAT CTCCAACAGC CGTCCATGCC 
GTCCGGGGAG GAGGTGGATC TTCAAACTCC ACTCACTACC AGAAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The Motor KIF5C Links the Requirements of Stable Microtubules and IGF-1 Receptor Membrane Insertion for Neuronal Polarization.
Molecular neurobiology54(8)6085-6096(2017 Oct)
Oksdath M,Guil AFN,Grassi D,Sosa LJ,Quiroga S

SKIP controls lysosome positioning using a composite kinesin-1 heavy and light chain-binding domain.
Journal of cell science130(9)1637-1651(2017 May)
Sanger A,Yip YY,Randall TS,Pernigo S,Steiner RA,Dodding MP

Kif5 regulates mitochondrial movement, morphology, function and neuronal survival.
Molecular and cellular neurosciences7222-33(2016 Apr)
Iworima DG,Pasqualotto BA,Rintoul GL

Regulation of mitochondrial transport in neurons.
Experimental cell research334(1)35-44(2015 May)
Lin MY,Sheng ZH

Effects of ?-tubulin K40 acetylation and detyrosination on kinesin-1 motility in a purified system.
Biophysical journal106(12)2636-43(2014 Jun)
Kaul N,Soppina V,Verhey KJ

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Kif5c cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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