Osmr cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Osmr
Entrez Gene ID	310132
Full Name	oncostatin M receptor
General protein information	Preferred Names oncostatin M receptor Names oncostatin-M-specific receptor subunit beta IL-31 receptor subunit beta IL-31R subunit beta IL-31R-beta IL-31RB interleukin-31 receptor subunit beta oncostatin M specific receptor
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q16
Summary	mouse homolog binds cytokine signalling subunits c12 protein and gp130 and acts as a receptor for the cytokine oncostatin M [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_006232012.3	XP_006232074.1	oncostatin-M-specific receptor subunit beta isoform X1
NM_001005384.1	NP_001005384.1	oncostatin-M-specific receptor subunit beta precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	OSMR	XP_005619429.1
Mus musculus (house mouse)	Osmr	NP_035149.2
Xenopus tropicalis (tropical clawed frog)	osmr	XP_004910505.1
Homo sapiens (human)	OSMR	NP_003990.1
	OSMR	XP_001083745.1
Bos taurus (cattle)	OSMR	NP_001073741.2
Rattus norvegicus (Norway rat)	Osmr	NP_001005384.1
Pan troglodytes (chimpanzee)	OSMR	XP_001141406.1
Gallus gallus (chicken)	OSMR	XP_004937260.1

Gene Ontology
Bibliography

Related articles in PubMed

Diverse functions of reactive cysteines facilitate unique biosynthetic processes of aggregate-prone interleukin-31.
Shen M, Siu S, Byrd S, Edelmann KH, Patel N, Ketchem RR, Mehlin C, Arnett HA, Hasegawa H
Experimental cell research317(7)976-93(2011 Apr)

CNTF mediates neurotrophic factor secretion and fluid absorption in human retinal pigment epithelium.
Li R, Wen R, Banzon T, Maminishkis A, Miller SS
PloS one6(9)e23148(2011)

Oncostatin M inhibits proliferation of rat oval cells, OC15-5, inducing differentiation into hepatocytes.
Okaya A, Kitanaka J, Kitanaka N, Satake M, Kim Y, Terada K, Sugiyama T, Takemura M, Fujimoto J, Terada N, Miyajima A, Tsujimura T
The American journal of pathology166(3)709-19(2005 Mar)

Reconstitution of the functional mouse oncostatin M (OSM) receptor: molecular cloning of the mouse OSM receptor beta subunit.
Tanaka M, Hara T, Copeland NG, Gilbert DJ, Jenkins NA, Miyajima A
Blood93(3)804-15(1999 Feb)

Cloning and characterization of a specific receptor for mouse oncostatin M.
Lindberg RA, Juan TS, Welcher AA, Sun Y, Cupples R, Guthrie B, Fletcher FA
Molecular and cellular biology18(6)3357-67(1998 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Osmr gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Osmr cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa10431	NM_001005384.1 Latest version!	Rattus norvegicus oncostatin M receptor (Osmr), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
ORa24450	XM_006232012.3 Latest version!	Rattus norvegicus oncostatin M receptor (Osmr), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Osmr ( NM_001005384.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001005384.1 Rattus norvegicus oncostatin M receptor (Osmr), mRNA.

Price & Availability↑

CloneID	ORa10431
Clone ID Related Accession (Same CDS sequence)	NM_001005384.1
Accession Version	NM_001005384.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2889bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Rattus norvegicus(Norway rat)
Product	oncostatin-M-specific receptor subunit beta precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB167522.1. On Oct 1, 2004 this sequence version replaced XM_226813.2. ##Evidence-Data-START## Transcript exon combination :: AB167522.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCTTTCT CTGTGGTCCT TCATCAAGTG ACCTTCCTTC TGGCAGTGCT GTCCCTGAGG 
ACTTCCCAAA GTAAAGTCTT GGGGGAGCCT TTACAGTTGA CTCCTGAGAT ACACACAGTT 
TCTCTTCAAT CTGCACTTCA AGAAGCGAAT TTAGAATGGA CTGTCCCAAC CTTTAGTCAT 
CAAGAATTAA ACATTGTATT TCAGATAGAG ATCAGTCGGA TGAGAACATC CAACACCATC 
TGGGTGGGGA ATTACAGCAC CACTGTGAAG CATGAAGAAA CTGTGCATTG GAAATGGACA 
TCTGATATCC CCTTGGAATG TGCCACACAT TTCATAAGAA TAAGGGCTAT GGTAGATGAC 
GCCCAGTACC CTCCACAGAG TTCCTGGAGC AACTGGAGTT CCTGGAAAGA AGTTAATGCA 
CAAGTTTCAG TTCCACCTGA TACATTATTA ATATTTCCTG AAGACAGACT GTTGGAAGAA 
GGTTCCAATG TCACCATCTG TTTGATGATT GGGCAGAATC TATATAATGT ATCCTGTAAG 
TTGCAAGAAG AGCCAATCCG TGGAGAGCAA CTTGATTCAC ACCTGTCACT AATAAAATTG 
AATAATGTAG TGTTCCTTAA CAACGCAGGG ACAAACATCA ATTGTAAAGC CATGAATGGT 
ACTAAAAATA CATTTGGTAC TGTTCTCTTT GTCTCAAAAG TGCTTGAGGA ACCTAAGAAT 
TTTTCCTGTG AAACCCGAGA CTTTAAGACT TTGAACTGTT TGTGGGAACC TGGGATAGAC 
ACGACTTTGA GTTGGCATAA ACAACGTTCC CAACACTACA CTTTATATGA ATCGTTCTCT 
GGGAGACGTG AGGTTTCTAA CCACAGAAAC TCGCATACCT GGCAAATCAC TGAAGACTCA 
CAGGAAACAT ATAACTTCAC TCTCACAGCT GAAAACAACC TAAGGAAAAG AAGTGTCAGC 
ATCAGTTTTA ACCTGACCCA CAGAGTTCAT CCAAAGGCTC CCCATGATGT CACTCTTAAA 
ACTGTAGGTG CTACAAAAGC CCACATGACT TGGAAGGTTC CCTCCCGTGG AGACTACACA 
CTTTTGTGTC AGGTTGAACT CCAGTGTGAA GGAGAAGTGA TACATGAGCA CAATGTTTCT 
GTCCACACGA GCGCCAACTA CCTCTTCAGT GATCTGGAGC CAGACACAGA GTACAAGGCT 
TGTGTGCGCT GTGCGAGTGC CAACCACTTC TGGAAATGGA GTGACTGGAT GCAAAAAAAG 
TTCAGAACAC CCGAGGCTGC CCCCTCAGAA GCTCTTGATG TGTGGAGAGA CGTGCGGACA 
GAGAATGGAA GACATGTTGT GACTTTATTC TGGAAGCCAC TATTAAAATC ACAGGCCAAT 
GGCAAAATCA TATCCTATAA TATAGTTGTA GAAAATGAAG CCAATCCAAC GGAGTCAGAA 
CAGTACTCTG TTCGGGCGCC AGCCCTTGGC ACAAACCTGA GCCTGGACCT GCATCCCTAC 
AAGATTCACA TCTCAGCCAA CAACAGCGCG GGGGCATCTC CTGAGTCCTT GGTGGTCCTT 
TCTAGTCATT CTGGACATGA AGAGGTCCAT GAAAAAACAA TTAAAGGTAT AAAGAATGGA 
TTCAATATTT CCTGGGAGCC GGTATCTGGA GACGCGATAG GCTATGTTGT GGACTGGTGT 
GCACATTCTC AGACCCAACG CTGTGATTTG CAGTGGAAGA ACGTAGGTCC CAATATCACA 
AGCACCATCA TCACCTCAGA CGCTTTTGAG CCAGGGGTCC GTTACAACTT CAGAATTTTT 
GAAAGATCTG TGGAAGAGAA TGTTCGGTTA GTAGAGAAAC AAAGAGGATA CACCCAGGAA 
TTGGCTCCGT CGGTGAATCC AGGAGTGACG ATTCATAACT TGACCCCAAA CTCCTTCAGT 
CTAAAATGGC AGGATTATGC CAGCGACTTC CAGTCTGGCT TTATAAAAGG GTACCTCGTA 
TATTTGAAAT CCAAGGAGCT GCAGTGCAAC CCAAACTGGG AGAGGACTGT TCTGTCAGAT 
AAGTCAGTGC TCTGTAAATA TGACGTCGAT GACCCAGAGA CAAAGACACT CACTGTGGAA 
AACCTTCGGC CAGAGTCCCT CTATGAGTTT CTCGTCACTC CATATACCAG CGCTGGCCAG 
GGACCCAATG AAACATACAC AAAGGTCACG ACTCCAGATG TACGCTCCCA CATGCTGCTG 
CAGATCATAT TACCCATGAC CCTCGGCGTC TTCCTCAGCA TCATTGTGTG TTACTGGAAA 
AGTCAGTGGG TGAAGGAGAA GTGCTATCCT GACATTCCCA ATCCATACAA GAGCAGCATC 
CTATCACTCA TAAAATCCAA GAAGAATCCT CACTTAATAA TGAATGTCAA AGACTGCATT 
CCAGATGTCC TTGAAGTTAT AAACAAAGCA GAAGGCAGCA AGACACAGTG TGTAGGCTCT 
GGGAAACTTC ACACTGAAGA TGTACCCACT AAGCCTCCAT TGGTGCCAAC AGAAAAGGAT 
TCCTCTGGCC CCATGCCCTT CGTCTTCCTT GAGAATTTTA CTTACGATCA GTCAGCTTTT 
GATTCTGGTT CTCATGGCTT CATTCCAGGA CCCCTAAAAA ACACACCGCA CCAACTCGGA 
CTATTGGCTC CGCCTAACAA GTTACAGAAT GTATTAGAAA ACGATTACAT GAAGTCCCTG 
GTCGAAAGTC CAACTGAAGA AACTAGTTTG ATTTATGTGT CCCAGCTGGC TTCACCTATA 
TGCGGAGACA AGGACAGTCT TGTCACGAAC CCACCCATGC CAGTGCACGG TTCAGAGTAT 
AAAAAGCAAA TGGCACTTCC AGGGAGCCTC ACATCAGCTT CTCTGAAGGA GAACAACTTG 
ACTTCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001005384.1
CDS	1..2889
Translation	MAFSVVLHQVTFLLAVLSLRTSQSKVLGEPLQLTPEIHTVSLQSALQEANLEWTVPTFSHQELNIVFQIEISRMRTSNTIWVGNYSTTVKHEETVHWKWTSDIPLECATHFIRIRAMVDDAQYPPQSSWSNWSSWKEVNAQVSVPPDTLLIFPEDRLLEEGSNVTICLMIGQNLYNVSCKLQEEPIRGEQLDSHLSLIKLNNVVFLNNAGTNINCKAMNGTKNTFGTVLFVSKVLEEPKNFSCETRDFKTLNCLWEPGIDTTLSWHKQRSQHYTLYESFSGRREVSNHRNSHTWQITEDSQETYNFTLTAENNLRKRSVSISFNLTHRVHPKAPHDVTLKTVGATKAHMTWKVPSRGDYTLLCQVELQCEGEVIHEHNVSVHTSANYLFSDLEPDTEYKACVRCASANHFWKWSDWMQKKFRTPEAAPSEALDVWRDVRTENGRHVVTLFWKPLLKSQANGKIISYNIVVENEANPTESEQYSVRAPALGTNLSLDLHPYKIHISANNSAGASPESLVVLSSHSGHEEVHEKTIKGIKNGFNISWEPVSGDAIGYVVDWCAHSQTQRCDLQWKNVGPNITSTIITSDAFEPGVRYNFRIFERSVEENVRLVEKQRGYTQELAPSVNPGVTIHNLTPNSFSLKWQDYASDFQSGFIKGYLVYLKSKELQCNPNWERTVLSDKSVLCKYDVDDPETKTLTVENLRPESLYEFLVTPYTSAGQGPNETYTKVTTPDVRSHMLLQIILPMTLGVFLSIIVCYWKSQWVKEKCYPDIPNPYKSSILSLIKSKKNPHLIMNVKDCIPDVLEVINKAEGSKTQCVGSGKLHTEDVPTKPPLVPTEKDSSGPMPFVFLENFTYDQSAFDSGSHGFIPGPLKNTPHQLGLLAPPNKLQNVLENDYMKSLVESPTEETSLIYVSQLASPICGDKDSLVTNPPMPVHGSEYKKQMALPGSLTSASLKENNLTS

Target ORF information:

RefSeq Version	NM_001005384.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus oncostatin M receptor (Osmr), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001005384.1

ORF Insert Sequence:

ATGGCTTTCT CTGTGGTCCT TCATCAAGTG ACCTTCCTTC TGGCAGTGCT GTCCCTGAGG 
ACTTCCCAAA GTAAAGTCTT GGGGGAGCCT TTACAGTTGA CTCCTGAGAT ACACACAGTT 
TCTCTTCAAT CTGCACTTCA AGAAGCGAAT TTAGAATGGA CTGTCCCAAC CTTTAGTCAT 
CAAGAATTAA ACATTGTATT TCAGATAGAG ATCAGTCGGA TGAGAACATC CAACACCATC 
TGGGTGGGGA ATTACAGCAC CACTGTGAAG CATGAAGAAA CTGTGCATTG GAAATGGACA 
TCTGATATCC CCTTGGAATG TGCCACACAT TTCATAAGAA TAAGGGCTAT GGTAGATGAC 
GCCCAGTACC CTCCACAGAG TTCCTGGAGC AACTGGAGTT CCTGGAAAGA AGTTAATGCA 
CAAGTTTCAG TTCCACCTGA TACATTATTA ATATTTCCTG AAGACAGACT GTTGGAAGAA 
GGTTCCAATG TCACCATCTG TTTGATGATT GGGCAGAATC TATATAATGT ATCCTGTAAG 
TTGCAAGAAG AGCCAATCCG TGGAGAGCAA CTTGATTCAC ACCTGTCACT AATAAAATTG 
AATAATGTAG TGTTCCTTAA CAACGCAGGG ACAAACATCA ATTGTAAAGC CATGAATGGT 
ACTAAAAATA CATTTGGTAC TGTTCTCTTT GTCTCAAAAG TGCTTGAGGA ACCTAAGAAT 
TTTTCCTGTG AAACCCGAGA CTTTAAGACT TTGAACTGTT TGTGGGAACC TGGGATAGAC 
ACGACTTTGA GTTGGCATAA ACAACGTTCC CAACACTACA CTTTATATGA ATCGTTCTCT 
GGGAGACGTG AGGTTTCTAA CCACAGAAAC TCGCATACCT GGCAAATCAC TGAAGACTCA 
CAGGAAACAT ATAACTTCAC TCTCACAGCT GAAAACAACC TAAGGAAAAG AAGTGTCAGC 
ATCAGTTTTA ACCTGACCCA CAGAGTTCAT CCAAAGGCTC CCCATGATGT CACTCTTAAA 
ACTGTAGGTG CTACAAAAGC CCACATGACT TGGAAGGTTC CCTCCCGTGG AGACTACACA 
CTTTTGTGTC AGGTTGAACT CCAGTGTGAA GGAGAAGTGA TACATGAGCA CAATGTTTCT 
GTCCACACGA GCGCCAACTA CCTCTTCAGT GATCTGGAGC CAGACACAGA GTACAAGGCT 
TGTGTGCGCT GTGCGAGTGC CAACCACTTC TGGAAATGGA GTGACTGGAT GCAAAAAAAG 
TTCAGAACAC CCGAGGCTGC CCCCTCAGAA GCTCTTGATG TGTGGAGAGA CGTGCGGACA 
GAGAATGGAA GACATGTTGT GACTTTATTC TGGAAGCCAC TATTAAAATC ACAGGCCAAT 
GGCAAAATCA TATCCTATAA TATAGTTGTA GAAAATGAAG CCAATCCAAC GGAGTCAGAA 
CAGTACTCTG TTCGGGCGCC AGCCCTTGGC ACAAACCTGA GCCTGGACCT GCATCCCTAC 
AAGATTCACA TCTCAGCCAA CAACAGCGCG GGGGCATCTC CTGAGTCCTT GGTGGTCCTT 
TCTAGTCATT CTGGACATGA AGAGGTCCAT GAAAAAACAA TTAAAGGTAT AAAGAATGGA 
TTCAATATTT CCTGGGAGCC GGTATCTGGA GACGCGATAG GCTATGTTGT GGACTGGTGT 
GCACATTCTC AGACCCAACG CTGTGATTTG CAGTGGAAGA ACGTAGGTCC CAATATCACA 
AGCACCATCA TCACCTCAGA CGCTTTTGAG CCAGGGGTCC GTTACAACTT CAGAATTTTT 
GAAAGATCTG TGGAAGAGAA TGTTCGGTTA GTAGAGAAAC AAAGAGGATA CACCCAGGAA 
TTGGCTCCGT CGGTGAATCC AGGAGTGACG ATTCATAACT TGACCCCAAA CTCCTTCAGT 
CTAAAATGGC AGGATTATGC CAGCGACTTC CAGTCTGGCT TTATAAAAGG GTACCTCGTA 
TATTTGAAAT CCAAGGAGCT GCAGTGCAAC CCAAACTGGG AGAGGACTGT TCTGTCAGAT 
AAGTCAGTGC TCTGTAAATA TGACGTCGAT GACCCAGAGA CAAAGACACT CACTGTGGAA 
AACCTTCGGC CAGAGTCCCT CTATGAGTTT CTCGTCACTC CATATACCAG CGCTGGCCAG 
GGACCCAATG AAACATACAC AAAGGTCACG ACTCCAGATG TACGCTCCCA CATGCTGCTG 
CAGATCATAT TACCCATGAC CCTCGGCGTC TTCCTCAGCA TCATTGTGTG TTACTGGAAA 
AGTCAGTGGG TGAAGGAGAA GTGCTATCCT GACATTCCCA ATCCATACAA GAGCAGCATC 
CTATCACTCA TAAAATCCAA GAAGAATCCT CACTTAATAA TGAATGTCAA AGACTGCATT 
CCAGATGTCC TTGAAGTTAT AAACAAAGCA GAAGGCAGCA AGACACAGTG TGTAGGCTCT 
GGGAAACTTC ACACTGAAGA TGTACCCACT AAGCCTCCAT TGGTGCCAAC AGAAAAGGAT 
TCCTCTGGCC CCATGCCCTT CGTCTTCCTT GAGAATTTTA CTTACGATCA GTCAGCTTTT 
GATTCTGGTT CTCATGGCTT CATTCCAGGA CCCCTAAAAA ACACACCGCA CCAACTCGGA 
CTATTGGCTC CGCCTAACAA GTTACAGAAT GTATTAGAAA ACGATTACAT GAAGTCCCTG 
GTCGAAAGTC CAACTGAAGA AACTAGTTTG ATTTATGTGT CCCAGCTGGC TTCACCTATA 
TGCGGAGACA AGGACAGTCT TGTCACGAAC CCACCCATGC CAGTGCACGG TTCAGAGTAT 
AAAAAGCAAA TGGCACTTCC AGGGAGCCTC ACATCAGCTT CTCTGAAGGA GAACAACTTG 
ACTTCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Osmr ( XM_006232012.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006232074.1 Rattus norvegicus oncostatin M receptor (Osmr), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa24450
Clone ID Related Accession (Same CDS sequence)	XM_006232012.3
Accession Version	XM_006232012.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2889bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	oncostatin-M-specific receptor subunit beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006232012.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTTCT CTGTGGTCCT TCATCAAGTG ACCTTCCTTC TGGCAGTGCT GTCCCTGAGG 
ACTTCCCGAA GTAAAGTCTT GGGGGAGCCT TTACAGTTGA CTCCTGAGAT ACACACAGTT 
TCTCTTCAAT CTGCACTTCA AGAAGCGAAT TTAGAATGGA CTGTCCCAAC CTTTAGTCAT 
CAAGAATTAA ACATTGTATT TCAGATAGAG ATCAGTCGGA TGAGAACATC CAACACCATC 
TGGGTGGGGA ATTACAGCAC CACTGTGAAG CATGAAGAAA CTGTGCATTG GAAATGGACA 
TCTGATATCC CCTTGGAATG TGCCACACAT TTCATAAGAA TAAGGGCTAT GGTAGATGAC 
ACCCAGTACC CTCCACAGAG TTCCTGGAGC AACTGGAGTT CCTGGAAAGA AGTTAATGCA 
CAAGTTTCAG TTCCACCTGA TACATTATTA ATATTTCCTG AAGACAGACT GTTGGAAGAA 
GGTTCCAATG TCACCATCTG TTTGATGATT GGGCAGAATC TATATAATGT ATCCTGTAAG 
TTGCAAGAAG AGCCAATCCG TGGAGAGCAA CTTGATTCAC ACCTGTCACT AATAAAATTG 
AATAATGTAG TGTTCCTTAA CAACGCAGGG ACAAACATCA ATTGTAAAGC CATGAATGGT 
ACTAAAAATA CATTTGGTAC TGTTCTCTTT GTCTCAAAAG TGCTTGAGGA ACCTAAGAAT 
TTTTCCTGTG AAACCCGAGA CTTTAAGACT TTGAACTGTT TGTGGGAACC TGGGATAGAC 
ACGACTTTGA GTTGGCATAA ACAACGTTCC CAACACTACA CTTTATATGA ATCGTTCTCT 
GGGAGACGTG AGGTTTCTAA CCACAGAAAC TCGCATACCT GGCAAATCAC TGAAGACTCA 
CAGGAAACAT ATAACTTCAC TCTCACAGCT GAAAACAACC TAAGGAAAAG AAGTGTCAGC 
ATCAGTTTTA ACCTGACCCA CAGAGTTCAT CCAAAGGCTC CCCATGATGT CACTCTTAAA 
ACTGTAGGTG CTACAAAAGC CCACATGACT TGGAAGGTTC CCTCCCGTGG AGACTACACA 
CTTTTGTGTC AGGTTGAACT CCAGTGTGAA GGAGAAGTGA TACATGAGCA CAACGTTTCT 
GTCCACACGA GCGCCAACTA CCTCTTCAGT GATCTGGAGC CAGACACAGA GTACAAGGCT 
TGTGTGCGCT GTGCGAGTGC CCACCACTTC TGGAAATGGA GTGACTGGAT GCAAAAAAAG 
TTCAGAACAC CCGAGGCTGC CCCCTCAGAA GCTCTTGATG TGTGGAGAGA CGTGCGGACA 
GAGAATGGAA GACATGTTGT GACTTTATTC TGGAAGCCAC TATTAAAATC ACAGGCCAAT 
GGCAAAATCA TATCCTATAA TATAGTTGTA GAAAATGAAG CCAATCCAAC GGAGTCAGAA 
CAGTACTCTG TTCGGGCGCC AGCCCTTGGC ACAAACCTGA GCCTGGACCT GCATCCCTAC 
AAGATTCACA TCTCAGCCAA CAACAGCGCG GGGGCATCTC CTGAGTCCTT GGTGGTCCTT 
TCTAGTCATT CTGGACATGG TAAAGTCCAT GAAAAAACAA TTAAAGGTAT AAAGAATGGA 
TTCAATATTT CCTGGGAGCC GGTATCTGGA GACGCGATAG GCTATGTTGT GGACTGGTGT 
GCACATTCTC AGACCCAACG CTGTGATTTG CAGTGGAAGA ACGTAGGTCC CAATATCACA 
AGCACCATCA TCACCTCAGA CGCTTTTGAG CCAGGGGTCC GTTACAACTT CAGAATTTTT 
GAAAGATCTG TGGAAGAGAA TGTTCGGTTA GTAGAGAAAC AAAGAGGATA CACCCAGGAA 
TTGGCTCCGT CGGTGAATCC AGGAGTGACG ATTCATAACT TGACCCCAAA CTCCTTCAGT 
CTAAAATGGC AGGATTATGC CAGCGACTTC CAGTCTGGCT TTATAAAAGG GTACCTCGTA 
TATTTGAAAT CCAAGGAGCT GCAGTGCAAC CCAAACTGGG AGAGGACTGT TCTGTCAGAT 
AAGTCAGTGC TCTGTAAATA TGACGTCGAT GACCCAGAGA CAAAGACACT CACTGTGGAA 
AACCTTCGGC CAGAGTCCCT CTATGAGTTT CTCGTCACTC CATATACCAG CGCTGGCCAG 
GGACCCAATG AAACATACAC AAAGGTCACG ACTCCAGATG TACGCTCCCA CATGCTGCTG 
CAGATCATAT TACCCATGAC CCTCGGCGTC TTCCTCAGCA TCATTGTGTG TTACTGGAAA 
AGTCAGTGGG TGAAGGAGAA GTGCTATCCT GACATTCCCA ATCCATACAA GAGCAGCATC 
CTATCACTCA TAAAATCCAA GAAGAATCCT CACTTAATAA TGAATGTCAA AGACTGCATT 
CCAGATGTCC TTGAAGTTAT AAACAAAGCA GAAGGCAGCA AGACACAGTG TGTAGGCTCT 
GGGAAACTTC ACACTGAAGA TGTACCCACT AAGCCTCCAT TGGTGCCAAC AGAAAAGGAT 
TCCTCTGGCC CCATGCCCTT CGTCTTCCTT GAGAATTTTA CTTACGATCA GTCAGCTTTT 
GATTCTGGTT CTCATGGCTT CATTCCAGGA CCCCTAAAAA ACACACCGCA CCAACTCGGA 
CTATTGGCTC CGCCTAACAA GTTACAGAAT GTATTAGAAA ATGATTACAT GAAGTCCCTG 
GTCGAAAGTC CAACTGAAGA AACTAGTTTG ATTTATGTGT CCCAGCTGGC TTCACCTATA 
TGCGGAGACA AGGACAGTCT TGTCACGAAC CCACCCATGC CAGTGTACGG TTCAGAGTAT 
AAAAAGCAAA TGGCACTTCC GGGGAGCCTC ACATCAGCTT CTCTGAAGGA GAACAACTTG 
ACTTCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006232074.1
CDS	591..3479
Translation	MAFSVVLHQVTFLLAVLSLRTSRSKVLGEPLQLTPEIHTVSLQSALQEANLEWTVPTFSHQELNIVFQIEISRMRTSNTIWVGNYSTTVKHEETVHWKWTSDIPLECATHFIRIRAMVDDTQYPPQSSWSNWSSWKEVNAQVSVPPDTLLIFPEDRLLEEGSNVTICLMIGQNLYNVSCKLQEEPIRGEQLDSHLSLIKLNNVVFLNNAGTNINCKAMNGTKNTFGTVLFVSKVLEEPKNFSCETRDFKTLNCLWEPGIDTTLSWHKQRSQHYTLYESFSGRREVSNHRNSHTWQITEDSQETYNFTLTAENNLRKRSVSISFNLTHRVHPKAPHDVTLKTVGATKAHMTWKVPSRGDYTLLCQVELQCEGEVIHEHNVSVHTSANYLFSDLEPDTEYKACVRCASAHHFWKWSDWMQKKFRTPEAAPSEALDVWRDVRTENGRHVVTLFWKPLLKSQANGKIISYNIVVENEANPTESEQYSVRAPALGTNLSLDLHPYKIHISANNSAGASPESLVVLSSHSGHGKVHEKTIKGIKNGFNISWEPVSGDAIGYVVDWCAHSQTQRCDLQWKNVGPNITSTIITSDAFEPGVRYNFRIFERSVEENVRLVEKQRGYTQELAPSVNPGVTIHNLTPNSFSLKWQDYASDFQSGFIKGYLVYLKSKELQCNPNWERTVLSDKSVLCKYDVDDPETKTLTVENLRPESLYEFLVTPYTSAGQGPNETYTKVTTPDVRSHMLLQIILPMTLGVFLSIIVCYWKSQWVKEKCYPDIPNPYKSSILSLIKSKKNPHLIMNVKDCIPDVLEVINKAEGSKTQCVGSGKLHTEDVPTKPPLVPTEKDSSGPMPFVFLENFTYDQSAFDSGSHGFIPGPLKNTPHQLGLLAPPNKLQNVLENDYMKSLVESPTEETSLIYVSQLASPICGDKDSLVTNPPMPVYGSEYKKQMALPGSLTSASLKENNLTS

Target ORF information:

RefSeq Version	XM_006232012.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus oncostatin M receptor (Osmr), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006232012.3

ORF Insert Sequence:

ATGGCTTTCT CTGTGGTCCT TCATCAAGTG ACCTTCCTTC TGGCAGTGCT GTCCCTGAGG 
ACTTCCCGAA GTAAAGTCTT GGGGGAGCCT TTACAGTTGA CTCCTGAGAT ACACACAGTT 
TCTCTTCAAT CTGCACTTCA AGAAGCGAAT TTAGAATGGA CTGTCCCAAC CTTTAGTCAT 
CAAGAATTAA ACATTGTATT TCAGATAGAG ATCAGTCGGA TGAGAACATC CAACACCATC 
TGGGTGGGGA ATTACAGCAC CACTGTGAAG CATGAAGAAA CTGTGCATTG GAAATGGACA 
TCTGATATCC CCTTGGAATG TGCCACACAT TTCATAAGAA TAAGGGCTAT GGTAGATGAC 
ACCCAGTACC CTCCACAGAG TTCCTGGAGC AACTGGAGTT CCTGGAAAGA AGTTAATGCA 
CAAGTTTCAG TTCCACCTGA TACATTATTA ATATTTCCTG AAGACAGACT GTTGGAAGAA 
GGTTCCAATG TCACCATCTG TTTGATGATT GGGCAGAATC TATATAATGT ATCCTGTAAG 
TTGCAAGAAG AGCCAATCCG TGGAGAGCAA CTTGATTCAC ACCTGTCACT AATAAAATTG 
AATAATGTAG TGTTCCTTAA CAACGCAGGG ACAAACATCA ATTGTAAAGC CATGAATGGT 
ACTAAAAATA CATTTGGTAC TGTTCTCTTT GTCTCAAAAG TGCTTGAGGA ACCTAAGAAT 
TTTTCCTGTG AAACCCGAGA CTTTAAGACT TTGAACTGTT TGTGGGAACC TGGGATAGAC 
ACGACTTTGA GTTGGCATAA ACAACGTTCC CAACACTACA CTTTATATGA ATCGTTCTCT 
GGGAGACGTG AGGTTTCTAA CCACAGAAAC TCGCATACCT GGCAAATCAC TGAAGACTCA 
CAGGAAACAT ATAACTTCAC TCTCACAGCT GAAAACAACC TAAGGAAAAG AAGTGTCAGC 
ATCAGTTTTA ACCTGACCCA CAGAGTTCAT CCAAAGGCTC CCCATGATGT CACTCTTAAA 
ACTGTAGGTG CTACAAAAGC CCACATGACT TGGAAGGTTC CCTCCCGTGG AGACTACACA 
CTTTTGTGTC AGGTTGAACT CCAGTGTGAA GGAGAAGTGA TACATGAGCA CAACGTTTCT 
GTCCACACGA GCGCCAACTA CCTCTTCAGT GATCTGGAGC CAGACACAGA GTACAAGGCT 
TGTGTGCGCT GTGCGAGTGC CCACCACTTC TGGAAATGGA GTGACTGGAT GCAAAAAAAG 
TTCAGAACAC CCGAGGCTGC CCCCTCAGAA GCTCTTGATG TGTGGAGAGA CGTGCGGACA 
GAGAATGGAA GACATGTTGT GACTTTATTC TGGAAGCCAC TATTAAAATC ACAGGCCAAT 
GGCAAAATCA TATCCTATAA TATAGTTGTA GAAAATGAAG CCAATCCAAC GGAGTCAGAA 
CAGTACTCTG TTCGGGCGCC AGCCCTTGGC ACAAACCTGA GCCTGGACCT GCATCCCTAC 
AAGATTCACA TCTCAGCCAA CAACAGCGCG GGGGCATCTC CTGAGTCCTT GGTGGTCCTT 
TCTAGTCATT CTGGACATGG TAAAGTCCAT GAAAAAACAA TTAAAGGTAT AAAGAATGGA 
TTCAATATTT CCTGGGAGCC GGTATCTGGA GACGCGATAG GCTATGTTGT GGACTGGTGT 
GCACATTCTC AGACCCAACG CTGTGATTTG CAGTGGAAGA ACGTAGGTCC CAATATCACA 
AGCACCATCA TCACCTCAGA CGCTTTTGAG CCAGGGGTCC GTTACAACTT CAGAATTTTT 
GAAAGATCTG TGGAAGAGAA TGTTCGGTTA GTAGAGAAAC AAAGAGGATA CACCCAGGAA 
TTGGCTCCGT CGGTGAATCC AGGAGTGACG ATTCATAACT TGACCCCAAA CTCCTTCAGT 
CTAAAATGGC AGGATTATGC CAGCGACTTC CAGTCTGGCT TTATAAAAGG GTACCTCGTA 
TATTTGAAAT CCAAGGAGCT GCAGTGCAAC CCAAACTGGG AGAGGACTGT TCTGTCAGAT 
AAGTCAGTGC TCTGTAAATA TGACGTCGAT GACCCAGAGA CAAAGACACT CACTGTGGAA 
AACCTTCGGC CAGAGTCCCT CTATGAGTTT CTCGTCACTC CATATACCAG CGCTGGCCAG 
GGACCCAATG AAACATACAC AAAGGTCACG ACTCCAGATG TACGCTCCCA CATGCTGCTG 
CAGATCATAT TACCCATGAC CCTCGGCGTC TTCCTCAGCA TCATTGTGTG TTACTGGAAA 
AGTCAGTGGG TGAAGGAGAA GTGCTATCCT GACATTCCCA ATCCATACAA GAGCAGCATC 
CTATCACTCA TAAAATCCAA GAAGAATCCT CACTTAATAA TGAATGTCAA AGACTGCATT 
CCAGATGTCC TTGAAGTTAT AAACAAAGCA GAAGGCAGCA AGACACAGTG TGTAGGCTCT 
GGGAAACTTC ACACTGAAGA TGTACCCACT AAGCCTCCAT TGGTGCCAAC AGAAAAGGAT 
TCCTCTGGCC CCATGCCCTT CGTCTTCCTT GAGAATTTTA CTTACGATCA GTCAGCTTTT 
GATTCTGGTT CTCATGGCTT CATTCCAGGA CCCCTAAAAA ACACACCGCA CCAACTCGGA 
CTATTGGCTC CGCCTAACAA GTTACAGAAT GTATTAGAAA ATGATTACAT GAAGTCCCTG 
GTCGAAAGTC CAACTGAAGA AACTAGTTTG ATTTATGTGT CCCAGCTGGC TTCACCTATA 
TGCGGAGACA AGGACAGTCT TGTCACGAAC CCACCCATGC CAGTGTACGG TTCAGAGTAT 
AAAAAGCAAA TGGCACTTCC GGGGAGCCTC ACATCAGCTT CTCTGAAGGA GAACAACTTG 
ACTTCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Diverse functions of reactive cysteines facilitate unique biosynthetic processes of aggregate-prone interleukin-31.
Experimental cell research317(7)976-93(2011 Apr)
Shen M,Siu S,Byrd S,Edelmann KH,Patel N,Ketchem RR,Mehlin C,Arnett HA,Hasegawa H

CNTF mediates neurotrophic factor secretion and fluid absorption in human retinal pigment epithelium.
PloS one6(9)e23148(2011)
Li R,Wen R,Banzon T,Maminishkis A,Miller SS

Oncostatin M inhibits proliferation of rat oval cells, OC15-5, inducing differentiation into hepatocytes.
The American journal of pathology166(3)709-19(2005 Mar)
Okaya A,Kitanaka J,Kitanaka N,Satake M,Kim Y,Terada K,Sugiyama T,Takemura M,Fujimoto J,Terada N,Miyajima A,Tsujimura T

Reconstitution of the functional mouse oncostatin M (OSM) receptor: molecular cloning of the mouse OSM receptor beta subunit.
Blood93(3)804-15(1999 Feb)
Tanaka M,Hara T,Copeland NG,Gilbert DJ,Jenkins NA,Miyajima A

Cloning and characterization of a specific receptor for mouse oncostatin M.
Molecular and cellular biology18(6)3357-67(1998 Jun)
Lindberg RA,Juan TS,Welcher AA,Sun Y,Cupples R,Guthrie B,Fletcher FA

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Osmr cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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