Rad17 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rad17
Entrez Gene ID	310034
Full Name	RAD17 checkpoint clamp loader component
General protein information	Preferred Names RAD17 checkpoint clamp loader component Names cell cycle checkpoint protein RAD17 RAD17 homolog
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q12

mRNA and Protein(s)

mRNA	Protein	Name
XM_006231848.3	XP_006231910.1	cell cycle checkpoint protein RAD17 isoform X1
NM_001024778.1	NP_001019949.1	cell cycle checkpoint protein RAD17

Pathways from BioSystems

Homologies

	RAD17	XP_001093481.1
Canis lupus familiaris (dog)	RAD17	XP_535265.2
Mus musculus (house mouse)	Rad17	NP_001037836.1
Gallus gallus (chicken)	RAD17	NP_998749.1
Bos taurus (cattle)	RAD17	NP_001096714.1
Danio rerio (zebrafish)	rad17	NP_001002661.1
Arabidopsis thaliana (thale cress)	ATRAD17	NP_201414.1
Oryza sativa (rice)	Os03g0242100	NP_001049521.2
Xenopus tropicalis (tropical clawed frog)	rad17	XP_002934861.1
Homo sapiens (human)	RAD17	NP_579917.1
Drosophila melanogaster (fruit fly)	Rad17	NP_650382.3
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008673	XP_314771.2
Pan troglodytes (chimpanzee)	RAD17	XP_003950588.1
Rattus norvegicus (Norway rat)	Rad17	NP_001019949.1

Gene Ontology
Bibliography

Related articles in PubMed

Interaction between human MCM7 and Rad17 proteins is required for replication checkpoint signaling.
Tsao CC, Geisen C, Abraham RT
The EMBO journal23(23)4660-9(2004 Nov)

Mutation of the mouse Rad17 gene leads to embryonic lethality and reveals a role in DNA damage-dependent recombination.
Budzowska M, Jaspers I, Essers J, de Waard H, van Drunen E, Hanada K, Beverloo B, Hendriks RW, de Klein A, Kanaar R, Hoeijmakers JH, Maas A
The EMBO journal23(17)3548-58(2004 Sep)

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a).
Herbig U, Jobling WA, Chen BP, Chen DJ, Sedivy JM
Molecular cell14(4)501-13(2004 May)

MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation.
Wang Y, Qin J
Proceedings of the National Academy of Sciences of the United States of America100(26)15387-92(2003 Dec)

HRad17 colocalizes with NHP2L1 in the nucleolus and redistributes after UV irradiation.
Chang MS, Sasaki H, Campbell MS, Kraeft SK, Sutherland R, Yang CY, Liu Y, Auclair D, Hao L, Sonoda H, Ferland LH, Chen LB
The Journal of biological chemistry274(51)36544-9(1999 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Rad17 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rad17 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06634	NM_001024778.1 Latest version!	Rattus norvegicus RAD17 checkpoint clamp loader component (Rad17), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$405.30 $579.00
ORa24350	XM_006231848.3 Latest version!	Rattus norvegicus RAD17 checkpoint clamp loader component (Rad17), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rad17 ( NM_001024778.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001019949.1 Rattus norvegicus RAD17 checkpoint clamp loader component (Rad17), mRNA.

Price & Availability↑

CloneID	ORa06634
Clone ID Related Accession (Same CDS sequence)	NM_001024778.1
Accession Version	NM_001024778.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2061bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	cell cycle checkpoint protein RAD17
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC098057.1. On Jun 10, 2005 this sequence version replaced XM_226718.3. ##Evidence-Data-START## Transcript exon combination :: BC098057.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGTCAGAAA CTTTCCTTAG ACCAAAGGTG TCTTCTACAA AGGTAACAGA CTGGGTAGAT 
CCGGCATTTG ATGACTTTTC AGCGAACACT GCTGTCACCA CCATCACCGT TTCATCTCTA 
AGTTTGAATA ACTCCAGTCA CAGAAGAAAA TACTTGCCCT CCACATTAGA AAGTAACAGA 
TTGTCTGCTA GGAAAAGAGG AAGGCTGCCT TTAGAACAGA CTAATGGTCT AGAAACGTCA 
AAAGAATATC TGTCTGACGA TGAGCCATGG GTGGATAAGT ATAAACCAGA AACTCAGCAT 
GAGCTTGCTG TCCATAAAAA GAAAATTGAA GAAGTTGAAA CCTGGTTAAA AACTCAAGTC 
TTAGAAGTGA AGCCGAAACA CGGTGGGTCT ATTTTATTAA TAACAGGTCC TCCAGGATGT 
GGAAAGACAA CTACTATAAA AATACTGTCA AAGGAGCTTG GGATTCAAGT ACAAGAATGG 
GTTAATCCCA TTTTACAAGA CTTCCAAAAA GATGATTACA AGGAGTTATT TAATTCAGAG 
TCAAACTTCT CTGTCATTCC ATACCAATCT CAGATAGCAG TCTTCAATGA CTTTCTGTTA 
AGAGCCACCA AGTACAACAA ATTGCAGATG CTTGGAGATG CCCTGACAAC AGATAAGAAG 
ATAATTCTGG TTGAGGATCT ACCTAACCAA TTTTATCGAG ATGCTAATGC TTTACACGAA 
ATTCTAAGGA AGTATGTGCA CATCGGCCGG TGTCCTCTTG TATTTATAGT CTCTGACAGT 
GTCAGTGGAG ATAGTAATCA TCGGTTACTC TTTCCCAAAA ACATTCAAGA AGAGTGTTCT 
GTTTCAAATA TTAGTTTCAA CCCTGTGGCA CCAACAATTA TGATGAAATT TCTTAATCGA 
ATTGTGACTA TAGAAGCTAG TAAGAATGGA GAAAAAATTA CTGTTCCTAA TAAAGCTTCT 
TTGGAGTTGC TCTGTCAAGG ATGTTCTGGT GATATCAGAA GTGCAATAAA CAGCCTGCAG 
TTTTCTTCTT CAAAAGGAGA GAACAGTTCA TGGTCAAAGA AGAAAAAGAT GTCATTGAAA 
TCAGATGCTT CGATTTCAAA AGCAAAGCAG AAAAGGAAAC ATAATAGTAC TTTGGAAAAT 
CAGGAGATTC AAGCTATTGG TGGAAAAGAT GTCTCTCTTT TTCTCTTCAG AGCTTTGGGG 
AAAATTCTGT ACTGTAAAAG AGCACCTTTA ACAGAGCTCG CCTCGCCTCG CCTGCCGGCT 
CACTTGTCAG AGCATGACCG GGATACTTTG CTTGTTCAGC CCGAGGAAAT AGTAGAAATG 
TCACACATGC CAGGAGAATT TTTTAATTTG TACCTTCACC AAAACTACAT AGATTTCTTC 
ACCGACGTAG ATGACCTTGT GAGAGCCAGT GAGTTTCTGA GTTTTGCAGA TATCCTCGGT 
GGTGACTGGA ATACGCGCTC TTCACTCAGG GACTATAGTA CATCTATAGC TGCAAGAGGT 
GTGATGCATT CCAATACATC TCGGAGATTC GCTCATTGCC AAGGAGGGGG ATCCAGCTTT 
CGACCCTTAC ATAAGCCCCA ATGGTTTCTA ATACAGAAAA AGTATCGGGA AAATTGCCTG 
GCAGCGAAAG CACTCTTCTG TGACTTCTGC CTACCCGCTG TGTGTCTGCA GACTCAGCTC 
TTGCCTTATC TTGCTCTTCT GACCATTCCA ATGCGAAACA AAGCTCAGAT TTCTTTTATC 
CAAGATATTG GAAGACTTCC TTTGAAGCGA AACTTTGGGA GGTTGAAAAT GGAGGCCCTG 
ACTGACCGAG AGCTCGGGCT CATAGACCCT GACAGCGGGG ATGAATTGCT GCACAGTGGA 
GGACAGCCTG CTCAGGAGGC TCAGGGCCAG CCCGCCCAGA CTGCTGACCC AGAAACCTGG 
TCTCTCCCTT TGAGTCAGAA CAGTGGGAGC GATCTGCCTG CCAGCCAGCC TCGGCCCTTT 
TCCTCCAAAG TGGACCTGGA AGAGGAGGAG GAGGAAGAGG AAGACATAGT AATAGAGGAC 
TATGACAGCG ATGAGGCATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001019949.1
CDS	212..2272
Translation	MSETFLRPKVSSTKVTDWVDPAFDDFSANTAVTTITVSSLSLNNSSHRRKYLPSTLESNRLSARKRGRLPLEQTNGLETSKEYLSDDEPWVDKYKPETQHELAVHKKKIEEVETWLKTQVLEVKPKHGGSILLITGPPGCGKTTTIKILSKELGIQVQEWVNPILQDFQKDDYKELFNSESNFSVIPYQSQIAVFNDFLLRATKYNKLQMLGDALTTDKKIILVEDLPNQFYRDANALHEILRKYVHIGRCPLVFIVSDSVSGDSNHRLLFPKNIQEECSVSNISFNPVAPTIMMKFLNRIVTIEASKNGEKITVPNKASLELLCQGCSGDIRSAINSLQFSSSKGENSSWSKKKKMSLKSDASISKAKQKRKHNSTLENQEIQAIGGKDVSLFLFRALGKILYCKRAPLTELASPRLPAHLSEHDRDTLLVQPEEIVEMSHMPGEFFNLYLHQNYIDFFTDVDDLVRASEFLSFADILGGDWNTRSSLRDYSTSIAARGVMHSNTSRRFAHCQGGGSSFRPLHKPQWFLIQKKYRENCLAAKALFCDFCLPAVCLQTQLLPYLALLTIPMRNKAQISFIQDIGRLPLKRNFGRLKMEALTDRELGLIDPDSGDELLHSGGQPAQEAQGQPAQTADPETWSLPLSQNSGSDLPASQPRPFSSKVDLEEEEEEEEDIVIEDYDSDEA

Target ORF information:

RefSeq Version	NM_001024778.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus RAD17 checkpoint clamp loader component (Rad17), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001024778.1

ORF Insert Sequence:

ATGTCAGAAA CTTTCCTTAG ACCAAAGGTG TCTTCTACAA AGGTAACAGA CTGGGTAGAT 
CCGGCATTTG ATGACTTTTC AGCGAACACT GCTGTCACCA CCATCACCGT TTCATCTCTA 
AGTTTGAATA ACTCCAGTCA CAGAAGAAAA TACTTGCCCT CCACATTAGA AAGTAACAGA 
TTGTCTGCTA GGAAAAGAGG AAGGCTGCCT TTAGAACAGA CTAATGGTCT AGAAACGTCA 
AAAGAATATC TGTCTGACGA TGAGCCATGG GTGGATAAGT ATAAACCAGA AACTCAGCAT 
GAGCTTGCTG TCCATAAAAA GAAAATTGAA GAAGTTGAAA CCTGGTTAAA AACTCAAGTC 
TTAGAAGTGA AGCCGAAACA CGGTGGGTCT ATTTTATTAA TAACAGGTCC TCCAGGATGT 
GGAAAGACAA CTACTATAAA AATACTGTCA AAGGAGCTTG GGATTCAAGT ACAAGAATGG 
GTTAATCCCA TTTTACAAGA CTTCCAAAAA GATGATTACA AGGAGTTATT TAATTCAGAG 
TCAAACTTCT CTGTCATTCC ATACCAATCT CAGATAGCAG TCTTCAATGA CTTTCTGTTA 
AGAGCCACCA AGTACAACAA ATTGCAGATG CTTGGAGATG CCCTGACAAC AGATAAGAAG 
ATAATTCTGG TTGAGGATCT ACCTAACCAA TTTTATCGAG ATGCTAATGC TTTACACGAA 
ATTCTAAGGA AGTATGTGCA CATCGGCCGG TGTCCTCTTG TATTTATAGT CTCTGACAGT 
GTCAGTGGAG ATAGTAATCA TCGGTTACTC TTTCCCAAAA ACATTCAAGA AGAGTGTTCT 
GTTTCAAATA TTAGTTTCAA CCCTGTGGCA CCAACAATTA TGATGAAATT TCTTAATCGA 
ATTGTGACTA TAGAAGCTAG TAAGAATGGA GAAAAAATTA CTGTTCCTAA TAAAGCTTCT 
TTGGAGTTGC TCTGTCAAGG ATGTTCTGGT GATATCAGAA GTGCAATAAA CAGCCTGCAG 
TTTTCTTCTT CAAAAGGAGA GAACAGTTCA TGGTCAAAGA AGAAAAAGAT GTCATTGAAA 
TCAGATGCTT CGATTTCAAA AGCAAAGCAG AAAAGGAAAC ATAATAGTAC TTTGGAAAAT 
CAGGAGATTC AAGCTATTGG TGGAAAAGAT GTCTCTCTTT TTCTCTTCAG AGCTTTGGGG 
AAAATTCTGT ACTGTAAAAG AGCACCTTTA ACAGAGCTCG CCTCGCCTCG CCTGCCGGCT 
CACTTGTCAG AGCATGACCG GGATACTTTG CTTGTTCAGC CCGAGGAAAT AGTAGAAATG 
TCACACATGC CAGGAGAATT TTTTAATTTG TACCTTCACC AAAACTACAT AGATTTCTTC 
ACCGACGTAG ATGACCTTGT GAGAGCCAGT GAGTTTCTGA GTTTTGCAGA TATCCTCGGT 
GGTGACTGGA ATACGCGCTC TTCACTCAGG GACTATAGTA CATCTATAGC TGCAAGAGGT 
GTGATGCATT CCAATACATC TCGGAGATTC GCTCATTGCC AAGGAGGGGG ATCCAGCTTT 
CGACCCTTAC ATAAGCCCCA ATGGTTTCTA ATACAGAAAA AGTATCGGGA AAATTGCCTG 
GCAGCGAAAG CACTCTTCTG TGACTTCTGC CTACCCGCTG TGTGTCTGCA GACTCAGCTC 
TTGCCTTATC TTGCTCTTCT GACCATTCCA ATGCGAAACA AAGCTCAGAT TTCTTTTATC 
CAAGATATTG GAAGACTTCC TTTGAAGCGA AACTTTGGGA GGTTGAAAAT GGAGGCCCTG 
ACTGACCGAG AGCTCGGGCT CATAGACCCT GACAGCGGGG ATGAATTGCT GCACAGTGGA 
GGACAGCCTG CTCAGGAGGC TCAGGGCCAG CCCGCCCAGA CTGCTGACCC AGAAACCTGG 
TCTCTCCCTT TGAGTCAGAA CAGTGGGAGC GATCTGCCTG CCAGCCAGCC TCGGCCCTTT 
TCCTCCAAAG TGGACCTGGA AGAGGAGGAG GAGGAAGAGG AAGACATAGT AATAGAGGAC 
TATGACAGCG ATGAGGCATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Rad17 ( XM_006231848.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006231910.1 Rattus norvegicus RAD17 checkpoint clamp loader component (Rad17), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa24350
Clone ID Related Accession (Same CDS sequence)	XM_006231848.3
Accession Version	XM_006231848.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2061bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	cell cycle checkpoint protein RAD17 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006231848.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCAGAAA CTTTCCTTAG ACCAAAGGTG TCTTCTACAA AGGTAACAGA CTGGGTAGAT 
CCGGCATTTG ATGACTTTTC AGCGAACACT GCTGTCACCA CCATCACCGT TTCATCTCTA 
AGTTTGAATA ACTCCAGTCA CAGAAGAAAA TACTTGCCCT CCACATTAGA AAGTAACAGA 
TTGTCTGCTA GGAAAAGAGG AAGGCTGCCT TTAGAACAGA CTAATGGTCT AGAAACGTCA 
AAAGAATATC TGTCTGACGA TGAGCCATGG GTGGATAAGT ATAAACCAGA AACTCAGCAT 
GAGCTTGCTG TCCATAAAAA GAAAATTGAA GAAGTTGAAA CCTGGTTAAA AACTCAAGTC 
TTAGAAGTGA AGCCGAAACA CGGTGGGTCT ATTTTATTAA TAACAGGTCC TCCAGGATGT 
GGAAAGACAA CTACTATAAA AATACTGTCA AAGGAGCTTG GGATTCAAGT ACAAGAATGG 
GTTAATCCCA TTTTACAAGA CTTCCAAAAA GATGATTACA AGGAGTTATT TAATTCAGAG 
TCAAACTTCT CTGTCATTCC ATACCAATCT CAGATAGCAG TCTTCAATGA CTTTCTGTTA 
AGAGCCACCA AGTACAACAA ATTGCAGATG CTTGGAGATG CCCTGACAAC AGATAAGAAG 
ATAATTCTGG TTGAGGATCT ACCTAACCAA TTTTATCGAG ATGCTAATGC TTTACACGAA 
ATTCTAAGGA AGTATGTGCA CATCGGCCGG TGTCCTCTTG TATTTATAGT CTCTGACAGT 
GTCAGTGGAG ATAGTAATCA TCGGTTACTC TTTCCCAAAA ACATTCAAGA AGAGTGTTCT 
GTTTCAAATA TTAGTTTCAA CCCTGTGGCA CCAACAATTA TGATGAAATT TCTTAATCGA 
ATTGTGACTA TAGAAGCTAG TAAGAATGGA GAAAAAATTA CTGTTCCTAA TAAAGCTTCT 
TTGGAGTTGC TCTGTCAAGG ATGTTCTGGT GATATCAGAA GTGCAATAAA CAGCCTGCAG 
TTTTCTTCTT CAAAAGGAGA GAACAGTTCA TGGTCAAAGA AGAAAAAGAT GTCATTGAAA 
TCAGATGCTT CGATTTCAAA AGCAAAGCAG AAAAGGAAAC ATAATAGTAC TTTGGAAAAT 
CAGGAGATTC AAGCTATTGG TGGAAAAGAT GTCTCTCTTT TTCTCTTCAG AGCTTTGGGG 
AAAATTCTGT ACTGTAAAAG AGCACCTTTA ACAGAGCTCG CCTCGCCTCG CCTGCCGGCT 
CACTTGTCAG AGCATGACCG GGATACTTTG CTTGTTCAGC CCGAGGAAAT AGTAGAAATG 
TCACACATGC CAGGAGAATT TTTTAATTTG TACCTTCACC AAAACTACAT AGATTTCTTC 
ACCGACGTAG ATGACCTTGT GAGAGCCAGT GAGTTTCTGA GTTTTGCAGA TATCCTCGGT 
GGTGACTGGA ATACGCGCTC TTCACTCAGG GACTATAGTA CATCTATAGC TGCAAGAGGT 
GTGATGCATT CCAATACATC TCGGAGATTC GCTCATTGCC AAGGAGGGGG ATCCAGCTTT 
CGACCCTTAC ATAAGCCCCA ATGGTTTCTA ATACAGAAAA AGTATCGGGA AAATTGCCTG 
GCAGCGAAAG CACTCTTCTG TGACTTCTGC CTACCCGCTG TGTGTCTGCA GACTCAGCTC 
TTGCCTTATC TTGCTCTTCT GACCATTCCA ATGCGAAACA AAGCTCAGAT TTCTTTTATC 
CAAGATATTG GAAGACTTCC TTTGAAGCGA AACTTTGGGA GGTTGAAAAT GGAGGCCCTG 
ACTGACCGAG AGCTCGGGCT CATAGACCCT GACAGCGGGG ATGAATTGCT GCACAGTGGA 
GGACAGCCTG CTCAGGAGGC TCAGGGCCAG CCCGCCCAGA CTGCTGACCC AGAAACCTGG 
TCTCTCCCTT TGAGTCAGAA CAGTGGGAGC GATCTGCCTG CCAGCCAGCC TCGGCCCTTT 
TCCTCCAAAG TGGACCTGGA AGAGGAGGAG GAGGAAGAGG AAGACATAGT AATAGAGGAC 
TATGACAGCG ATGAGACATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006231910.1
CDS	198..2258
Translation	MSETFLRPKVSSTKVTDWVDPAFDDFSANTAVTTITVSSLSLNNSSHRRKYLPSTLESNRLSARKRGRLPLEQTNGLETSKEYLSDDEPWVDKYKPETQHELAVHKKKIEEVETWLKTQVLEVKPKHGGSILLITGPPGCGKTTTIKILSKELGIQVQEWVNPILQDFQKDDYKELFNSESNFSVIPYQSQIAVFNDFLLRATKYNKLQMLGDALTTDKKIILVEDLPNQFYRDANALHEILRKYVHIGRCPLVFIVSDSVSGDSNHRLLFPKNIQEECSVSNISFNPVAPTIMMKFLNRIVTIEASKNGEKITVPNKASLELLCQGCSGDIRSAINSLQFSSSKGENSSWSKKKKMSLKSDASISKAKQKRKHNSTLENQEIQAIGGKDVSLFLFRALGKILYCKRAPLTELASPRLPAHLSEHDRDTLLVQPEEIVEMSHMPGEFFNLYLHQNYIDFFTDVDDLVRASEFLSFADILGGDWNTRSSLRDYSTSIAARGVMHSNTSRRFAHCQGGGSSFRPLHKPQWFLIQKKYRENCLAAKALFCDFCLPAVCLQTQLLPYLALLTIPMRNKAQISFIQDIGRLPLKRNFGRLKMEALTDRELGLIDPDSGDELLHSGGQPAQEAQGQPAQTADPETWSLPLSQNSGSDLPASQPRPFSSKVDLEEEEEEEEDIVIEDYDSDET

Target ORF information:

RefSeq Version	XM_006231848.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus RAD17 checkpoint clamp loader component (Rad17), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006231848.3

ORF Insert Sequence:

ATGTCAGAAA CTTTCCTTAG ACCAAAGGTG TCTTCTACAA AGGTAACAGA CTGGGTAGAT 
CCGGCATTTG ATGACTTTTC AGCGAACACT GCTGTCACCA CCATCACCGT TTCATCTCTA 
AGTTTGAATA ACTCCAGTCA CAGAAGAAAA TACTTGCCCT CCACATTAGA AAGTAACAGA 
TTGTCTGCTA GGAAAAGAGG AAGGCTGCCT TTAGAACAGA CTAATGGTCT AGAAACGTCA 
AAAGAATATC TGTCTGACGA TGAGCCATGG GTGGATAAGT ATAAACCAGA AACTCAGCAT 
GAGCTTGCTG TCCATAAAAA GAAAATTGAA GAAGTTGAAA CCTGGTTAAA AACTCAAGTC 
TTAGAAGTGA AGCCGAAACA CGGTGGGTCT ATTTTATTAA TAACAGGTCC TCCAGGATGT 
GGAAAGACAA CTACTATAAA AATACTGTCA AAGGAGCTTG GGATTCAAGT ACAAGAATGG 
GTTAATCCCA TTTTACAAGA CTTCCAAAAA GATGATTACA AGGAGTTATT TAATTCAGAG 
TCAAACTTCT CTGTCATTCC ATACCAATCT CAGATAGCAG TCTTCAATGA CTTTCTGTTA 
AGAGCCACCA AGTACAACAA ATTGCAGATG CTTGGAGATG CCCTGACAAC AGATAAGAAG 
ATAATTCTGG TTGAGGATCT ACCTAACCAA TTTTATCGAG ATGCTAATGC TTTACACGAA 
ATTCTAAGGA AGTATGTGCA CATCGGCCGG TGTCCTCTTG TATTTATAGT CTCTGACAGT 
GTCAGTGGAG ATAGTAATCA TCGGTTACTC TTTCCCAAAA ACATTCAAGA AGAGTGTTCT 
GTTTCAAATA TTAGTTTCAA CCCTGTGGCA CCAACAATTA TGATGAAATT TCTTAATCGA 
ATTGTGACTA TAGAAGCTAG TAAGAATGGA GAAAAAATTA CTGTTCCTAA TAAAGCTTCT 
TTGGAGTTGC TCTGTCAAGG ATGTTCTGGT GATATCAGAA GTGCAATAAA CAGCCTGCAG 
TTTTCTTCTT CAAAAGGAGA GAACAGTTCA TGGTCAAAGA AGAAAAAGAT GTCATTGAAA 
TCAGATGCTT CGATTTCAAA AGCAAAGCAG AAAAGGAAAC ATAATAGTAC TTTGGAAAAT 
CAGGAGATTC AAGCTATTGG TGGAAAAGAT GTCTCTCTTT TTCTCTTCAG AGCTTTGGGG 
AAAATTCTGT ACTGTAAAAG AGCACCTTTA ACAGAGCTCG CCTCGCCTCG CCTGCCGGCT 
CACTTGTCAG AGCATGACCG GGATACTTTG CTTGTTCAGC CCGAGGAAAT AGTAGAAATG 
TCACACATGC CAGGAGAATT TTTTAATTTG TACCTTCACC AAAACTACAT AGATTTCTTC 
ACCGACGTAG ATGACCTTGT GAGAGCCAGT GAGTTTCTGA GTTTTGCAGA TATCCTCGGT 
GGTGACTGGA ATACGCGCTC TTCACTCAGG GACTATAGTA CATCTATAGC TGCAAGAGGT 
GTGATGCATT CCAATACATC TCGGAGATTC GCTCATTGCC AAGGAGGGGG ATCCAGCTTT 
CGACCCTTAC ATAAGCCCCA ATGGTTTCTA ATACAGAAAA AGTATCGGGA AAATTGCCTG 
GCAGCGAAAG CACTCTTCTG TGACTTCTGC CTACCCGCTG TGTGTCTGCA GACTCAGCTC 
TTGCCTTATC TTGCTCTTCT GACCATTCCA ATGCGAAACA AAGCTCAGAT TTCTTTTATC 
CAAGATATTG GAAGACTTCC TTTGAAGCGA AACTTTGGGA GGTTGAAAAT GGAGGCCCTG 
ACTGACCGAG AGCTCGGGCT CATAGACCCT GACAGCGGGG ATGAATTGCT GCACAGTGGA 
GGACAGCCTG CTCAGGAGGC TCAGGGCCAG CCCGCCCAGA CTGCTGACCC AGAAACCTGG 
TCTCTCCCTT TGAGTCAGAA CAGTGGGAGC GATCTGCCTG CCAGCCAGCC TCGGCCCTTT 
TCCTCCAAAG TGGACCTGGA AGAGGAGGAG GAGGAAGAGG AAGACATAGT AATAGAGGAC 
TATGACAGCG ATGAGACATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Interaction between human MCM7 and Rad17 proteins is required for replication checkpoint signaling.
The EMBO journal23(23)4660-9(2004 Nov)
Tsao CC,Geisen C,Abraham RT

Mutation of the mouse Rad17 gene leads to embryonic lethality and reveals a role in DNA damage-dependent recombination.
The EMBO journal23(17)3548-58(2004 Sep)
Budzowska M,Jaspers I,Essers J,de Waard H,van Drunen E,Hanada K,Beverloo B,Hendriks RW,de Klein A,Kanaar R,Hoeijmakers JH,Maas A

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a).
Molecular cell14(4)501-13(2004 May)
Herbig U,Jobling WA,Chen BP,Chen DJ,Sedivy JM

MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation.
Proceedings of the National Academy of Sciences of the United States of America100(26)15387-92(2003 Dec)
Wang Y,Qin J

HRad17 colocalizes with NHP2L1 in the nucleolus and redistributes after UV irradiation.
The Journal of biological chemistry274(51)36544-9(1999 Dec)
Chang MS,Sasaki H,Campbell MS,Kraeft SK,Sutherland R,Yang CY,Liu Y,Auclair D,Hao L,Sonoda H,Ferland LH,Chen LB

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Rad17 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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