Adamts14 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Adamts14
Entrez Gene ID	309837
Full Name	ADAM metallopeptidase with thrombospondin type 1 motif, 14
General protein information	Preferred Names ADAM metallopeptidase with thrombospondin type 1 motif, 14 Names A disintegrin and metalloproteinase with thrombospondin motifs 14 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 14
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 20 Map Location: 20q11

mRNA and Protein(s)

mRNA	Protein	Name
XM_006256449.3	XP_006256511.1	A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X1
NM_001107636.1	NP_001101106.1	A disintegrin and metalloproteinase with thrombospondin motifs 14 precursor

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Adamts14	NP_001101106.1
Pan troglodytes (chimpanzee)	ADAMTS14	XP_507838.2
Mus musculus (house mouse)	Adamts14	NP_001074596.1
Gallus gallus (chicken)	ADAMTS14	XP_004942102.1
Homo sapiens (human)	ADAMTS14	NP_631894.2
	ADAMTS14	XP_001107840.1
Canis lupus familiaris (dog)	ADAMTS14	XP_005619041.1
Xenopus tropicalis (tropical clawed frog)	adamts14	XP_002936397.2
Bos taurus (cattle)	ADAMTS14	NP_001179176.1

Gene Ontology
Bibliography

Related articles in PubMed

Pentosan polysulfate decreases myocardial expression of the extracellular matrix enzyme ADAMTS4 and improves cardiac function in vivo in rats subjected to pressure overload by aortic banding.
Vistnes M, Aronsen JM, Lunde IG, Sjaastad I, Carlson CR, Christensen G
PloS one9(3)e89621(2014)

Association of a nsSNP in ADAMTS14 to some osteoarthritis phenotypes.
Rodriguez-Lopez J, Pombo-Suarez M, Loughlin J, Tsezou A, Blanco FJ, Meulenbelt I, Slagboom PE, Valdes AM, Spector TD, Gomez-Reino JJ, Gonzalez A
Osteoarthritis and cartilage17(3)321-7(2009 Mar)

Genetic association between polymorphisms in the ADAMTS14 gene and multiple sclerosis.
Goertsches R, Comabella M, Navarro A, Perkal H, Montalban X
Journal of neuroimmunology164(1-2)140-7(2005 Jul)

Cloning and characterization of ADAMTS-14, a novel ADAMTS displaying high homology with ADAMTS-2 and ADAMTS-3.
Colige A, Vandenberghe I, Thiry M, Lambert CA, Van Beeumen J, Li SW, Prockop DJ, Lapiere CM, Nusgens BV
The Journal of biological chemistry277(8)5756-66(2002 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

discovered that myocardial mRNA and protein levels of ADAMTS1 and -4, and mRNA levels of versican, aggrecan, and ADAMTS8 increased after AB, and TNF-alpha and IL-1beta synergistically increased mRNA of versican and ADAMTS4
Title: Pentosan polysulfate decreases myocardial expression of the extracellular matrix enzyme ADAMTS4 and improves cardiac function in vivo in rats subjected to pressure overload by aortic banding.

The following Adamts14 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Adamts14 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa11422	NM_001107636.1 Latest version!	Rattus norvegicus ADAM metallopeptidase with thrombospondin type 1 motif, 14 (Adamts14), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$825.30 $1179.00
ORa39457	XM_006256449.3 Latest version!	Rattus norvegicus ADAM metallopeptidase with thrombospondin type 1 motif, 14 (Adamts14), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Adamts14 ( NM_001107636.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101106.1 Rattus norvegicus ADAM metallopeptidase with thrombospondin type 1 motif, 14 (Adamts14), mRNA.

Price & Availability↑

CloneID	ORa11422
Clone ID Related Accession (Same CDS sequence)	NM_001107636.1
Accession Version	NM_001107636.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3381bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Rattus norvegicus(Norway rat)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 14 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH474016.2. On or before Oct 4, 2007 this sequence version replaced XM_228290.4, XM_001055182.1. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN02642806, SAMN04563758 [ECO:0000350] ##Evidence-Data-END##

ATGGCTCGGC TCCGCGCTCT GCTCCACTGC CTGCTGCCCT GGTACTGCGC GCTTTGCGCC 
GCCGCCGGCA GTCAGACCCC AGACCCACGC CTCTCTGGGA AACTTCATGA CTATGTCGTG 
ACTGTGCCCT GCAGCACGGA TTTCCAGGGA CGATTCTTGT CCCACGTGGT GTCTGCTCCC 
GCAGCTGCCT CCTCCCGGAG CCACCTCCGG GTGGCTCGAA GTCCCCTGAG CCTGGAAAGA 
GAGACACCAC GTCCAAGGCA CCATTTCCTC TACTTCAATG TGACTGTCTT TGGGAAGTTG 
CTCCACTTGA GGCTGCAGCC CAACCGGAGG TTGGTGGCAC CAGGGGCCCC GGTGGAATGG 
CAGGAGGACT TTCGGGAACT CTTCCGCCAA CCCTTGCAGC GGGAGTGTGT GTACACCGGA 
GGTGTCACTG GAATGCCTGG GGCAGCTGTA GCCATCAGCA ATTGTGACGG ATTGGCTGGC 
CTCATCCGCA CAGACAACTC AGACTTCTTC ATTGAGCCTC TGGAGCGAGG GCAGCAGGAG 
AAAGAGGCTG GCGGGAGGAC CCACGTGGTA TACCGCCGGG AAGCCGTCCA GAGGGAGTGG 
ACAGAGCCTC ATGGGGACCT CCACAATGAA GCCTTCGGCC TTGGTGACCT TCCCAATGTG 
CTGGATCTGG TAGGGGACCA GCTGGGTGAC ACAGAGCGGA AGCGGCGACA CGCCAAGCCT 
GGCAGCTACA GCATCGAGGT GCTGCTGGCA GTGGACGACT CGGTGGTTCG CTTCCACGGC 
AGGGAGCACA CGCAGAACTA CGTGCTCACG CTCATGAACA TCGTGGATGA AATCTACCAT 
GATGAATCGC TGGGGGCCCA CGTGAACATT GCCCTTGTCC GCCTGATCAT GGTGGGCTAC 
CGACAGTCCC TGAGCCTGAT CGAGCGAGGG AACCCAGCAC GCAGCCTGGA GCAGGTGTGT 
CGCTGGGCAC ACTCCCAGCA GCGCCAGGAC CCTAGCCACA CTGAACATCA CGACCACGTC 
ATCTTCCTCA CCCGCCAGAA CTTCGGCCCC TCAGGCTTGG CATGGAGCAT GATGGCCAAG 
GCAATGGCTG TGATGACGAG ACCAGTCTGG GCAGCGTCAT GGCGCCCCTG GTTCAGGCTG 
CCTTCCACCG CTTTCATTGG TCTCGCTGCA GCAAGCTGGA ACTCAGCCGT TACCTCCCGT 
AGGTTACCCA GCCGCTACCT CCTATCCTAC AATTGCCTCC TTGATGACCC CTTCGAGCGC 
ACCTGGCCCC AGCCCCCGGA ACTGCCCGGG ATCGACTACT CCATGGACGA GCAGTGCCGG 
TTCGACTTTG GCACTGGGTA CCACACCTGC TTGGCTTTCA GAACCTTTGA ACCCTGCAAG 
CAGCTGTGGT GCAGCCACCC CGACAACCCA TACTTCTGCA AGACCAAGAA GGGGCCTCCA 
CTGGATGGGA CAGAGTGTGC ACCAGGCAAG TGGTGCTTCA AAGGCCATTG TGTCTGGAAG 
TCGCCAGAGC AGACTTATGG CCAGGACGGA GGCTGGAGCT CCTGGACCAA CTTCGGCTCA 
TGTTCTCGGT CATGCGGAGG TGGGGTGCGG TCCCGAAGCC GGAGCTGCGA CAACCCTCCT 
CCAGCCTATG GAGGTCGCCT GTGCTCAGGG CCCATGTTTG AGTACCAGAT CTGCAACAGT 
GAGGACTGTC CTGGGCCCTT CGAGGACTTC CGGGCCCAGC AGTGTGCCAA GCGAAACTCC 
TACTATACCC ACCAGGATGC CAAGCACAGC TGGTTGCCCT ATGAGCCGGA CAGTGAGGCC 
CAGAAGTGCG AGCTCATTTG TCAGTCGGCA GACACCGGAG ACGTGGTGTT TATGAACCAA 
GTGGTGCATG ATGGGACGCG CTGCAGTTAC CGAGATCCTT ACAGTGTCTG TGCCCGTGGA 
GAGTGCGTGC CCTTTGGTTG CGACAAGGAG GTGGGATCCA TGAAGACGGA TGACAAGTGC 
GGTGTCTGCG GTGGGGACAA CTCTCACTGC AGGACTGTGA AGGGGACACT GGGAAAGGCC 
TCCAAGCAAG CAGCGGCTCT CAAACAGGTG CAGATCCCGG CGGGCGCCAG GCACATTCAG 
ATTGAGTTGC TGGAGAAGGC TCCCCGCCGT ATTGCGGTGA AGAATCAGGT GACTGGAAGC 
TTCATCCTCA ACCCCAAGGG CAAGGAGGCC TCTAGCAGGA CATTCACTGC GCTGGGCCTG 
GAATGGGAGC ACGCAGCGGA GGACACCAAG GATAGCCTCA AGACCAACGG ACCCTTGCCT 
GAAGCCATCG CCGTCCTGGT TCTCCCCCCG GCTGAGGGTA AACCCCGAGG TAGCCTGGCC 
TACAAGTATG TCATCCACGA GGACCTGCTG CCCCTCATTG GGAGCAATAA TGTGCTCCTG 
GAAGAGATGG ACAGCTATGA GTGGGCTCTC AAGAGCTGGT CTCCCTGCAG CAAGGCCTGT 
GGAGGAGGAA TCCAGTTCAC TAAATACGGC TGCCGGCACC GCAGGGACCA CCACATGGTG 
CAGCGGCACC TGTGTGACCA TAAAAAGAGG CCCAAGGCTA TTCGACGGCG TTGCAACCAG 
CACCCGTGTC CCCAGCCCAC GTGGGTGACA GAAGAGTGGG GTGCCTGCAG CCGGAGCTGT 
GGGAAGCTGG GGCTGCAGAC CAGGGGGGTG CAGTGCCTGC TGCCTCTCTC CAACGGCACC 
CATAAGGCCA TGCCAGCCAA GGCTTGCCTA GGTAACCGGC CAGAGGCCAA GAGGCCATGC 
CTCCGTGTGC CCTGCCCAGC CCAGTGGCGG ACTGGAGCCT GGTCCCAGTG CTCTGCCACC 
TGTGGAAAAG GCATCCAGCA ACGGCAGGTC GTGTGCAGGA ACAGCTCCAG TGCCCTCGGG 
CCATGTGAGG GGGTCAAGCC GGACACCGTG CGGATCTGCA GCCAGCCAGC CTGTGGAGGA 
GATCTCCAGA ACTCTACAGT GAATGCAGAG GTCCAGGACC CTGTGACTAA AATGGGACCC 
TGGGAACCCC AATCCAGGCC CCTGACTCCC ATGAACAGGA TCTCAACAAT GGAGCCCTGT 
GTGGGAGACA GATCCGTCTT CTGCCGGATG GAAGTGCTGG ACCGTTACTG CACCATCCCT 
GGCTACCTCC GGCTGTGTTG TGAGTCTTGC ATAAAGAAGG CCTCGAGCTC CAATGCCAGC 
CTGGCCTCAC TACCCACCTT CTCCACCCCT GGGAGTCTCT TGCCAGAACC CACGGCCACC 
CAGGAGGACA TGGAATCTAC AAGGGGGCCA ACCAGACTGG AAGATCATCG GCAAAGCCAG 
CCCACACAGC TCTCAGGGGC GGTGGACAGG ATCTCCTCAG TAACTCAGCA TCTGGTCACC 
CCCCCAGATG CTAAGCCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101106.1
CDS	1..3381
Translation	MARLRALLHCLLPWYCALCAAAGSQTPDPRLSGKLHDYVVTVPCSTDFQGRFLSHVVSAPAAASSRSHLRVARSPLSLERETPRPRHHFLYFNVTVFGKLLHLRLQPNRRLVAPGAPVEWQEDFRELFRQPLQRECVYTGGVTGMPGAAVAISNCDGLAGLIRTDNSDFFIEPLERGQQEKEAGGRTHVVYRREAVQREWTEPHGDLHNEAFGLGDLPNVLDLVGDQLGDTERKRRHAKPGSYSIEVLLAVDDSVVRFHGREHTQNYVLTLMNIVDEIYHDESLGAHVNIALVRLIMVGYRQSLSLIERGNPARSLEQVCRWAHSQQRQDPSHTEHHDHVIFLTRQNFGPSGLAWSMMAKAMAVMTRPVWAASWRPWFRLPSTAFIGLAAASWNSAVTSRRLPSRYLLSYNCLLDDPFERTWPQPPELPGIDYSMDEQCRFDFGTGYHTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFKGHCVWKSPEQTYGQDGGWSSWTNFGSCSRSCGGGVRSRSRSCDNPPPAYGGRLCSGPMFEYQICNSEDCPGPFEDFRAQQCAKRNSYYTHQDAKHSWLPYEPDSEAQKCELICQSADTGDVVFMNQVVHDGTRCSYRDPYSVCARGECVPFGCDKEVGSMKTDDKCGVCGGDNSHCRTVKGTLGKASKQAAALKQVQIPAGARHIQIELLEKAPRRIAVKNQVTGSFILNPKGKEASSRTFTALGLEWEHAAEDTKDSLKTNGPLPEAIAVLVLPPAEGKPRGSLAYKYVIHEDLLPLIGSNNVLLEEMDSYEWALKSWSPCSKACGGGIQFTKYGCRHRRDHHMVQRHLCDHKKRPKAIRRRCNQHPCPQPTWVTEEWGACSRSCGKLGLQTRGVQCLLPLSNGTHKAMPAKACLGNRPEAKRPCLRVPCPAQWRTGAWSQCSATCGKGIQQRQVVCRNSSSALGPCEGVKPDTVRICSQPACGGDLQNSTVNAEVQDPVTKMGPWEPQSRPLTPMNRISTMEPCVGDRSVFCRMEVLDRYCTIPGYLRLCCESCIKKASSSNASLASLPTFSTPGSLLPEPTATQEDMESTRGPTRLEDHRQSQPTQLSGAVDRISSVTQHLVTPPDAKP

Target ORF information:

RefSeq Version	NM_001107636.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ADAM metallopeptidase with thrombospondin type 1 motif, 14 (Adamts14), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001107636.1

ORF Insert Sequence:

ATGGCTCGGC TCCGCGCTCT GCTCCACTGC CTGCTGCCCT GGTACTGCGC GCTTTGCGCC 
GCCGCCGGCA GTCAGACCCC AGACCCACGC CTCTCTGGGA AACTTCATGA CTATGTCGTG 
ACTGTGCCCT GCAGCACGGA TTTCCAGGGA CGATTCTTGT CCCACGTGGT GTCTGCTCCC 
GCAGCTGCCT CCTCCCGGAG CCACCTCCGG GTGGCTCGAA GTCCCCTGAG CCTGGAAAGA 
GAGACACCAC GTCCAAGGCA CCATTTCCTC TACTTCAATG TGACTGTCTT TGGGAAGTTG 
CTCCACTTGA GGCTGCAGCC CAACCGGAGG TTGGTGGCAC CAGGGGCCCC GGTGGAATGG 
CAGGAGGACT TTCGGGAACT CTTCCGCCAA CCCTTGCAGC GGGAGTGTGT GTACACCGGA 
GGTGTCACTG GAATGCCTGG GGCAGCTGTA GCCATCAGCA ATTGTGACGG ATTGGCTGGC 
CTCATCCGCA CAGACAACTC AGACTTCTTC ATTGAGCCTC TGGAGCGAGG GCAGCAGGAG 
AAAGAGGCTG GCGGGAGGAC CCACGTGGTA TACCGCCGGG AAGCCGTCCA GAGGGAGTGG 
ACAGAGCCTC ATGGGGACCT CCACAATGAA GCCTTCGGCC TTGGTGACCT TCCCAATGTG 
CTGGATCTGG TAGGGGACCA GCTGGGTGAC ACAGAGCGGA AGCGGCGACA CGCCAAGCCT 
GGCAGCTACA GCATCGAGGT GCTGCTGGCA GTGGACGACT CGGTGGTTCG CTTCCACGGC 
AGGGAGCACA CGCAGAACTA CGTGCTCACG CTCATGAACA TCGTGGATGA AATCTACCAT 
GATGAATCGC TGGGGGCCCA CGTGAACATT GCCCTTGTCC GCCTGATCAT GGTGGGCTAC 
CGACAGTCCC TGAGCCTGAT CGAGCGAGGG AACCCAGCAC GCAGCCTGGA GCAGGTGTGT 
CGCTGGGCAC ACTCCCAGCA GCGCCAGGAC CCTAGCCACA CTGAACATCA CGACCACGTC 
ATCTTCCTCA CCCGCCAGAA CTTCGGCCCC TCAGGCTTGG CATGGAGCAT GATGGCCAAG 
GCAATGGCTG TGATGACGAG ACCAGTCTGG GCAGCGTCAT GGCGCCCCTG GTTCAGGCTG 
CCTTCCACCG CTTTCATTGG TCTCGCTGCA GCAAGCTGGA ACTCAGCCGT TACCTCCCGT 
AGGTTACCCA GCCGCTACCT CCTATCCTAC AATTGCCTCC TTGATGACCC CTTCGAGCGC 
ACCTGGCCCC AGCCCCCGGA ACTGCCCGGG ATCGACTACT CCATGGACGA GCAGTGCCGG 
TTCGACTTTG GCACTGGGTA CCACACCTGC TTGGCTTTCA GAACCTTTGA ACCCTGCAAG 
CAGCTGTGGT GCAGCCACCC CGACAACCCA TACTTCTGCA AGACCAAGAA GGGGCCTCCA 
CTGGATGGGA CAGAGTGTGC ACCAGGCAAG TGGTGCTTCA AAGGCCATTG TGTCTGGAAG 
TCGCCAGAGC AGACTTATGG CCAGGACGGA GGCTGGAGCT CCTGGACCAA CTTCGGCTCA 
TGTTCTCGGT CATGCGGAGG TGGGGTGCGG TCCCGAAGCC GGAGCTGCGA CAACCCTCCT 
CCAGCCTATG GAGGTCGCCT GTGCTCAGGG CCCATGTTTG AGTACCAGAT CTGCAACAGT 
GAGGACTGTC CTGGGCCCTT CGAGGACTTC CGGGCCCAGC AGTGTGCCAA GCGAAACTCC 
TACTATACCC ACCAGGATGC CAAGCACAGC TGGTTGCCCT ATGAGCCGGA CAGTGAGGCC 
CAGAAGTGCG AGCTCATTTG TCAGTCGGCA GACACCGGAG ACGTGGTGTT TATGAACCAA 
GTGGTGCATG ATGGGACGCG CTGCAGTTAC CGAGATCCTT ACAGTGTCTG TGCCCGTGGA 
GAGTGCGTGC CCTTTGGTTG CGACAAGGAG GTGGGATCCA TGAAGACGGA TGACAAGTGC 
GGTGTCTGCG GTGGGGACAA CTCTCACTGC AGGACTGTGA AGGGGACACT GGGAAAGGCC 
TCCAAGCAAG CAGCGGCTCT CAAACAGGTG CAGATCCCGG CGGGCGCCAG GCACATTCAG 
ATTGAGTTGC TGGAGAAGGC TCCCCGCCGT ATTGCGGTGA AGAATCAGGT GACTGGAAGC 
TTCATCCTCA ACCCCAAGGG CAAGGAGGCC TCTAGCAGGA CATTCACTGC GCTGGGCCTG 
GAATGGGAGC ACGCAGCGGA GGACACCAAG GATAGCCTCA AGACCAACGG ACCCTTGCCT 
GAAGCCATCG CCGTCCTGGT TCTCCCCCCG GCTGAGGGTA AACCCCGAGG TAGCCTGGCC 
TACAAGTATG TCATCCACGA GGACCTGCTG CCCCTCATTG GGAGCAATAA TGTGCTCCTG 
GAAGAGATGG ACAGCTATGA GTGGGCTCTC AAGAGCTGGT CTCCCTGCAG CAAGGCCTGT 
GGAGGAGGAA TCCAGTTCAC TAAATACGGC TGCCGGCACC GCAGGGACCA CCACATGGTG 
CAGCGGCACC TGTGTGACCA TAAAAAGAGG CCCAAGGCTA TTCGACGGCG TTGCAACCAG 
CACCCGTGTC CCCAGCCCAC GTGGGTGACA GAAGAGTGGG GTGCCTGCAG CCGGAGCTGT 
GGGAAGCTGG GGCTGCAGAC CAGGGGGGTG CAGTGCCTGC TGCCTCTCTC CAACGGCACC 
CATAAGGCCA TGCCAGCCAA GGCTTGCCTA GGTAACCGGC CAGAGGCCAA GAGGCCATGC 
CTCCGTGTGC CCTGCCCAGC CCAGTGGCGG ACTGGAGCCT GGTCCCAGTG CTCTGCCACC 
TGTGGAAAAG GCATCCAGCA ACGGCAGGTC GTGTGCAGGA ACAGCTCCAG TGCCCTCGGG 
CCATGTGAGG GGGTCAAGCC GGACACCGTG CGGATCTGCA GCCAGCCAGC CTGTGGAGGA 
GATCTCCAGA ACTCTACAGT GAATGCAGAG GTCCAGGACC CTGTGACTAA AATGGGACCC 
TGGGAACCCC AATCCAGGCC CCTGACTCCC ATGAACAGGA TCTCAACAAT GGAGCCCTGT 
GTGGGAGACA GATCCGTCTT CTGCCGGATG GAAGTGCTGG ACCGTTACTG CACCATCCCT 
GGCTACCTCC GGCTGTGTTG TGAGTCTTGC ATAAAGAAGG CCTCGAGCTC CAATGCCAGC 
CTGGCCTCAC TACCCACCTT CTCCACCCCT GGGAGTCTCT TGCCAGAACC CACGGCCACC 
CAGGAGGACA TGGAATCTAC AAGGGGGCCA ACCAGACTGG AAGATCATCG GCAAAGCCAG 
CCCACACAGC TCTCAGGGGC GGTGGACAGG ATCTCCTCAG TAACTCAGCA TCTGGTCACC 
CCCCCAGATG CTAAGCCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Adamts14 ( XM_006256449.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006256511.1 Rattus norvegicus ADAM metallopeptidase with thrombospondin type 1 motif, 14 (Adamts14), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa39457
Clone ID Related Accession (Same CDS sequence)	XM_006256449.3
Accession Version	XM_006256449.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3612bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005119.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006256449.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTCGGC TCCGCGCTCT GCTCCACTGC CTGCTGCCCT GGTACTGCGC GCTTTGCGCC 
GCCGCCGGCA GTCAGACCCC AGACCCACGC CTCTCTGGGA AACTTCATGA CTATGTCGTG 
ACTGTGCCCT GCAGCACGGA TTTCCAGGGA CGATTCTTGT CCCACGTGGT GTCTGCTCCC 
GCAGCTGCCT CCTCCCGGAG CCACCTCCGG GTGGCTCGAA GTCCCCTGAG CCTGGAAAGA 
GAGACACCAC GTCCAAGGCA CCATTTCCTC TACTTCAATG TGACTGTCTT TGGGAAGTTG 
CTCCACTTGA GGCTGCAGCC CAACCGGAGG TTGGTGGCAC CAGGGGCCCC GGTGGAATGG 
CAGGAGGACT TTCGGGAACT CTTCCGCCAA CCCTTGCAGC GGGAGTGTGT GTACACCGGA 
GGTGTCACTG GAATGCCTGG GGCAGCTGTA GCCATCAGCA ATTGTGACGG ATTGGCTGGC 
CTCATCCGCA CAGACAACTC AGACTTCTTC ATTGAGCCTC TGGAGCGAGG GCAGCAGGAG 
AAAGAGGCTG GCGGGAGGAC CCACGTGGTA TACCGCCGGG AAGCCGTCCA GAGGGAGTGG 
ACAGAGCCTC ATGGGGACCT CCACAATGAA GCCTTCGGCC TTGGTGACCT TCCCAATGTG 
CTGGATCTGG TAGGGGACCA GCTGGGTGAC ACAGAGCGGA AGCGGCGACA CGCCAAGCCT 
GGCAGCTACA GCATCGAGGT GCTGCTGGCA GTGGACGACT CGGTGGTTCG CTTCCACGGC 
AGGGAGCACA CGCAGAACTA CGTGCTCACG CTCATGAACA TCGTGGATGA AATCTACCAT 
GATGAATCGC TGGGGGCCCA CGTGAACATT GCCCTTGTCC GCCTGATCAT GGTGGGCTAC 
CGACAGTCCC TGAGCCTGAT CGAGCGAGGG AACCCAGCAC GCAGCCTGGA GCAGGTGTGT 
CGCTGGGCAC ACTCCCAGCA GCGCCAGGAC CCTAGCCACA CTGAACATCA CGACCACGTC 
ATCTTCCTCA CCCGCCAGAA CTTCGGCCCC TCAGGGTACG CACCTGTTAC TGGCATGTGC 
CACCCCCTAA GGAGCTGTGC CCTCAACCAC GAGGATGGCT TCTCCTCAGC TTTTGTCGTG 
GCTCATGAGA CAGGTCATGT GCTTGGCATG GAGCATGATG GCCAAGGCAA TGGCTGTGAT 
GACGAGACCA GTCTGGGCAG CGTCATGGCG CCCCTGGTTC AGGCTGCCTT CCACCGCTTT 
CATTGGTCTC GCTGCAGCAA GCTGGAACTC AGCCGTTACC TCCCATCCTA CAATTGCCTC 
CTTGATGACC CCTTCGAGCG CACCTGGCCC CAGCCCCCGG AACTGCCCGG GATCGACTAC 
TCCATGGACG AGCAGTGCCG GTTCGACTTT GGCACTGGGT ACCACACCTG CTTGGCTTTC 
AGAACCTTTG AACCCTGCAA GCAGCTGTGG TGCAGCCACC CCGACAACCC ATACTTCTGC 
AAGACCAAGA AGGGGCCTCC ACTGGATGGG ACAGAGTGTG CACCAGGCAA GTGGTGCTTC 
AAAGGCCATT GTGTCTGGAA GTCGCCAGAG CAGACTTATG GCCAGGACGG AGGCTGGAGC 
TCCTGGACCA ACTTCGGCTC ATGTTCTCGG TCATGCGGAG GTGGGGTGCG GTCCCGAAGC 
CGGAGCTGCG ACAACCCTCC TCCAGCCTAT GGAGGTCGCC TGTGCTCAGG GCCCATGTTT 
GAGTACCAGA TCTGCAACAG TGAGGACTGT CCTGGGCCCT TCGAGGACTT CCGGGCCCAG 
CAGTGTGCCA AGCGAAACTC CTACTATACC CACCAGGATG CCAAGCACAG CTGGTTGCCC 
TATGAGCCGG ACAGTGAGGC CCAGAAGTGC GAGCTCATTT GTCAGTCGGC AGACACCGGA 
GACGTGGTGT TTATGAACCA AGTGGTGCAT GATGGGACGC GCTGCAGTTA CCGAGATCCT 
TACAGTGTCT GTGCCCGTGG AGAGTGCGTG CCCTTTGGTT GCGACAAGGA GGTGGGATCC 
ATGAAGACGG ATGACAAGTG CGGTGTCTGC GGTGGGGACA ACTCTCACTG CAGGACTGTG 
AAGGGGACAC TGGGAAAGGC CTCCAAGCAA GCAGCGGCTC TCAAACAGGT GCAGATCCCG 
GCGGGCGCCA GGCACATTCA GATTGAGTTG CTGGAGAAGG CTCCCCGCCG TATTGCGGTG 
AAGAATCAGG TGACTGGAAG CTTCATCCTC AACCCCAAGG GCAAGGAGGC CTCTAGCAGG 
ACATTCACTG CGCTGGGCCT GGAATGGGAG CACGCAGCGG AGGACACCAA GGATAGCCTC 
AAGACCAACG GACCCTTGCC TGAAGCCATC GCCGTCCTGG TTCTCCCCCC GGCTGAGGGT 
AAACCCCGAG GTAGCCTGGC CTACAAGTAT GTCATCCACG AGGACCTGCT GCCCCTCATT 
GGGAGCAATA ATGTGCTCCT GGAAGAGATG GACAGCTATG AGTGGGCTCT CAAGAGCTGG 
TCTCCCTGCA GCAAGGCCTG TGGAGGAGGA ATCCAGTTCA CTAAATACGG CTGCCGGCAC 
CGCAGGGACC ACCACATGGT GCAGCGGCAC CTGTGTGACC ATAAAAAGAG GCCCAAGGCT 
ATTCGACGGC GTTGCAACCA GCACCCGTGT CCCCAGCCCA CGTGGGTGAC AGAAGAGTGG 
GGTGCCTGCA GCCGGAGCTG TGGGAAGCTG GGGCTGCAGA CCAGGGGGGT GCAGTGCCTG 
CTGCCTCTCT CCAACGGCAC CCATAAGGCC ATGCCAGCCA AGGCTTGCCT AGGTAACCGG 
CCAGAGGCCA AGAGGCCATG CCTCCGTGTG CCCTGCCCAG CCCAGTGGCG GACTGGAGCC 
TGGTCCCAGT GCTCTGCCAC CTGTGGAAAA GGCATCCAGC AACGGCAGGT CGTGTGCAGG 
AACAGCTCCA GTGCCCTCGG GCCATGTGAG GGGGTCAAGC CGGACACCGT GCGGATCTGC 
AGCCAGCCAG CCTGTGGAGG AGATCTCCAG AACTCTACAG TGAATGCAGA GGTCCAGGAC 
CCTGTGACTA AAATGGGACC CTGGGAACCC CAATCCAGGC CCCTGACTCC CATGAACAGG 
ATCTCAACAA TGGAGCCCTG TGTGGGAGAC AGATCCGTCT TCTGCCGGAT GGAAGTGCTG 
GACCGTTACT GCACCATCCC TGGCTACCTC CGGCTGTGTT GTGAGTCTTG CATAAAGAAG 
GCCTCGAGCT CCAATGCCAG CCTGGCCTCA CTACCCACCT TCTCCACCCC TGGGAGTCTC 
TTGCCAGAAC CCACGGCCAC CCAGGAGGAC ATGGAATCTA CAAGGGGGCC AACCAGACTG 
GAAGATCATC GGCAAAGCCA GCCCACACAG CTCTCAGGGG CGGTGGACAG GATCTCCTCA 
GTAACTCAGC ATCTGGTCAC CCCCCAGATG CTAAGCCCTA AAGCCTCTGA GAGCAATTCT 
CCCGCCACCC CACAGGGCCC ACCTTGGGGC CGGACCCAAA CAGCTGTGCC AACCTCTGAG 
GGTCAAGGAC AGTCCAGGGA GGAACCAGGA CATTCAGGCA CCAGCCTTCC CACAACCTCC 
CCAGTGACAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006256511.1
CDS	186..3797
Translation	MARLRALLHCLLPWYCALCAAAGSQTPDPRLSGKLHDYVVTVPCSTDFQGRFLSHVVSAPAAASSRSHLRVARSPLSLERETPRPRHHFLYFNVTVFGKLLHLRLQPNRRLVAPGAPVEWQEDFRELFRQPLQRECVYTGGVTGMPGAAVAISNCDGLAGLIRTDNSDFFIEPLERGQQEKEAGGRTHVVYRREAVQREWTEPHGDLHNEAFGLGDLPNVLDLVGDQLGDTERKRRHAKPGSYSIEVLLAVDDSVVRFHGREHTQNYVLTLMNIVDEIYHDESLGAHVNIALVRLIMVGYRQSLSLIERGNPARSLEQVCRWAHSQQRQDPSHTEHHDHVIFLTRQNFGPSGYAPVTGMCHPLRSCALNHEDGFSSAFVVAHETGHVLGMEHDGQGNGCDDETSLGSVMAPLVQAAFHRFHWSRCSKLELSRYLPSYNCLLDDPFERTWPQPPELPGIDYSMDEQCRFDFGTGYHTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCFKGHCVWKSPEQTYGQDGGWSSWTNFGSCSRSCGGGVRSRSRSCDNPPPAYGGRLCSGPMFEYQICNSEDCPGPFEDFRAQQCAKRNSYYTHQDAKHSWLPYEPDSEAQKCELICQSADTGDVVFMNQVVHDGTRCSYRDPYSVCARGECVPFGCDKEVGSMKTDDKCGVCGGDNSHCRTVKGTLGKASKQAAALKQVQIPAGARHIQIELLEKAPRRIAVKNQVTGSFILNPKGKEASSRTFTALGLEWEHAAEDTKDSLKTNGPLPEAIAVLVLPPAEGKPRGSLAYKYVIHEDLLPLIGSNNVLLEEMDSYEWALKSWSPCSKACGGGIQFTKYGCRHRRDHHMVQRHLCDHKKRPKAIRRRCNQHPCPQPTWVTEEWGACSRSCGKLGLQTRGVQCLLPLSNGTHKAMPAKACLGNRPEAKRPCLRVPCPAQWRTGAWSQCSATCGKGIQQRQVVCRNSSSALGPCEGVKPDTVRICSQPACGGDLQNSTVNAEVQDPVTKMGPWEPQSRPLTPMNRISTMEPCVGDRSVFCRMEVLDRYCTIPGYLRLCCESCIKKASSSNASLASLPTFSTPGSLLPEPTATQEDMESTRGPTRLEDHRQSQPTQLSGAVDRISSVTQHLVTPQMLSPKASESNSPATPQGPPWGRTQTAVPTSEGQGQSREEPGHSGTSLPTTSPVT

Target ORF information:

RefSeq Version	XM_006256449.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ADAM metallopeptidase with thrombospondin type 1 motif, 14 (Adamts14), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006256449.3

ORF Insert Sequence:

ATGGCTCGGC TCCGCGCTCT GCTCCACTGC CTGCTGCCCT GGTACTGCGC GCTTTGCGCC 
GCCGCCGGCA GTCAGACCCC AGACCCACGC CTCTCTGGGA AACTTCATGA CTATGTCGTG 
ACTGTGCCCT GCAGCACGGA TTTCCAGGGA CGATTCTTGT CCCACGTGGT GTCTGCTCCC 
GCAGCTGCCT CCTCCCGGAG CCACCTCCGG GTGGCTCGAA GTCCCCTGAG CCTGGAAAGA 
GAGACACCAC GTCCAAGGCA CCATTTCCTC TACTTCAATG TGACTGTCTT TGGGAAGTTG 
CTCCACTTGA GGCTGCAGCC CAACCGGAGG TTGGTGGCAC CAGGGGCCCC GGTGGAATGG 
CAGGAGGACT TTCGGGAACT CTTCCGCCAA CCCTTGCAGC GGGAGTGTGT GTACACCGGA 
GGTGTCACTG GAATGCCTGG GGCAGCTGTA GCCATCAGCA ATTGTGACGG ATTGGCTGGC 
CTCATCCGCA CAGACAACTC AGACTTCTTC ATTGAGCCTC TGGAGCGAGG GCAGCAGGAG 
AAAGAGGCTG GCGGGAGGAC CCACGTGGTA TACCGCCGGG AAGCCGTCCA GAGGGAGTGG 
ACAGAGCCTC ATGGGGACCT CCACAATGAA GCCTTCGGCC TTGGTGACCT TCCCAATGTG 
CTGGATCTGG TAGGGGACCA GCTGGGTGAC ACAGAGCGGA AGCGGCGACA CGCCAAGCCT 
GGCAGCTACA GCATCGAGGT GCTGCTGGCA GTGGACGACT CGGTGGTTCG CTTCCACGGC 
AGGGAGCACA CGCAGAACTA CGTGCTCACG CTCATGAACA TCGTGGATGA AATCTACCAT 
GATGAATCGC TGGGGGCCCA CGTGAACATT GCCCTTGTCC GCCTGATCAT GGTGGGCTAC 
CGACAGTCCC TGAGCCTGAT CGAGCGAGGG AACCCAGCAC GCAGCCTGGA GCAGGTGTGT 
CGCTGGGCAC ACTCCCAGCA GCGCCAGGAC CCTAGCCACA CTGAACATCA CGACCACGTC 
ATCTTCCTCA CCCGCCAGAA CTTCGGCCCC TCAGGGTACG CACCTGTTAC TGGCATGTGC 
CACCCCCTAA GGAGCTGTGC CCTCAACCAC GAGGATGGCT TCTCCTCAGC TTTTGTCGTG 
GCTCATGAGA CAGGTCATGT GCTTGGCATG GAGCATGATG GCCAAGGCAA TGGCTGTGAT 
GACGAGACCA GTCTGGGCAG CGTCATGGCG CCCCTGGTTC AGGCTGCCTT CCACCGCTTT 
CATTGGTCTC GCTGCAGCAA GCTGGAACTC AGCCGTTACC TCCCATCCTA CAATTGCCTC 
CTTGATGACC CCTTCGAGCG CACCTGGCCC CAGCCCCCGG AACTGCCCGG GATCGACTAC 
TCCATGGACG AGCAGTGCCG GTTCGACTTT GGCACTGGGT ACCACACCTG CTTGGCTTTC 
AGAACCTTTG AACCCTGCAA GCAGCTGTGG TGCAGCCACC CCGACAACCC ATACTTCTGC 
AAGACCAAGA AGGGGCCTCC ACTGGATGGG ACAGAGTGTG CACCAGGCAA GTGGTGCTTC 
AAAGGCCATT GTGTCTGGAA GTCGCCAGAG CAGACTTATG GCCAGGACGG AGGCTGGAGC 
TCCTGGACCA ACTTCGGCTC ATGTTCTCGG TCATGCGGAG GTGGGGTGCG GTCCCGAAGC 
CGGAGCTGCG ACAACCCTCC TCCAGCCTAT GGAGGTCGCC TGTGCTCAGG GCCCATGTTT 
GAGTACCAGA TCTGCAACAG TGAGGACTGT CCTGGGCCCT TCGAGGACTT CCGGGCCCAG 
CAGTGTGCCA AGCGAAACTC CTACTATACC CACCAGGATG CCAAGCACAG CTGGTTGCCC 
TATGAGCCGG ACAGTGAGGC CCAGAAGTGC GAGCTCATTT GTCAGTCGGC AGACACCGGA 
GACGTGGTGT TTATGAACCA AGTGGTGCAT GATGGGACGC GCTGCAGTTA CCGAGATCCT 
TACAGTGTCT GTGCCCGTGG AGAGTGCGTG CCCTTTGGTT GCGACAAGGA GGTGGGATCC 
ATGAAGACGG ATGACAAGTG CGGTGTCTGC GGTGGGGACA ACTCTCACTG CAGGACTGTG 
AAGGGGACAC TGGGAAAGGC CTCCAAGCAA GCAGCGGCTC TCAAACAGGT GCAGATCCCG 
GCGGGCGCCA GGCACATTCA GATTGAGTTG CTGGAGAAGG CTCCCCGCCG TATTGCGGTG 
AAGAATCAGG TGACTGGAAG CTTCATCCTC AACCCCAAGG GCAAGGAGGC CTCTAGCAGG 
ACATTCACTG CGCTGGGCCT GGAATGGGAG CACGCAGCGG AGGACACCAA GGATAGCCTC 
AAGACCAACG GACCCTTGCC TGAAGCCATC GCCGTCCTGG TTCTCCCCCC GGCTGAGGGT 
AAACCCCGAG GTAGCCTGGC CTACAAGTAT GTCATCCACG AGGACCTGCT GCCCCTCATT 
GGGAGCAATA ATGTGCTCCT GGAAGAGATG GACAGCTATG AGTGGGCTCT CAAGAGCTGG 
TCTCCCTGCA GCAAGGCCTG TGGAGGAGGA ATCCAGTTCA CTAAATACGG CTGCCGGCAC 
CGCAGGGACC ACCACATGGT GCAGCGGCAC CTGTGTGACC ATAAAAAGAG GCCCAAGGCT 
ATTCGACGGC GTTGCAACCA GCACCCGTGT CCCCAGCCCA CGTGGGTGAC AGAAGAGTGG 
GGTGCCTGCA GCCGGAGCTG TGGGAAGCTG GGGCTGCAGA CCAGGGGGGT GCAGTGCCTG 
CTGCCTCTCT CCAACGGCAC CCATAAGGCC ATGCCAGCCA AGGCTTGCCT AGGTAACCGG 
CCAGAGGCCA AGAGGCCATG CCTCCGTGTG CCCTGCCCAG CCCAGTGGCG GACTGGAGCC 
TGGTCCCAGT GCTCTGCCAC CTGTGGAAAA GGCATCCAGC AACGGCAGGT CGTGTGCAGG 
AACAGCTCCA GTGCCCTCGG GCCATGTGAG GGGGTCAAGC CGGACACCGT GCGGATCTGC 
AGCCAGCCAG CCTGTGGAGG AGATCTCCAG AACTCTACAG TGAATGCAGA GGTCCAGGAC 
CCTGTGACTA AAATGGGACC CTGGGAACCC CAATCCAGGC CCCTGACTCC CATGAACAGG 
ATCTCAACAA TGGAGCCCTG TGTGGGAGAC AGATCCGTCT TCTGCCGGAT GGAAGTGCTG 
GACCGTTACT GCACCATCCC TGGCTACCTC CGGCTGTGTT GTGAGTCTTG CATAAAGAAG 
GCCTCGAGCT CCAATGCCAG CCTGGCCTCA CTACCCACCT TCTCCACCCC TGGGAGTCTC 
TTGCCAGAAC CCACGGCCAC CCAGGAGGAC ATGGAATCTA CAAGGGGGCC AACCAGACTG 
GAAGATCATC GGCAAAGCCA GCCCACACAG CTCTCAGGGG CGGTGGACAG GATCTCCTCA 
GTAACTCAGC ATCTGGTCAC CCCCCAGATG CTAAGCCCTA AAGCCTCTGA GAGCAATTCT 
CCCGCCACCC CACAGGGCCC ACCTTGGGGC CGGACCCAAA CAGCTGTGCC AACCTCTGAG 
GGTCAAGGAC AGTCCAGGGA GGAACCAGGA CATTCAGGCA CCAGCCTTCC CACAACCTCC 
CCAGTGACAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Pentosan polysulfate decreases myocardial expression of the extracellular matrix enzyme ADAMTS4 and improves cardiac function in vivo in rats subjected to pressure overload by aortic banding.
PloS one9(3)e89621(2014)
Vistnes M,Aronsen JM,Lunde IG,Sjaastad I,Carlson CR,Christensen G

Association of a nsSNP in ADAMTS14 to some osteoarthritis phenotypes.
Osteoarthritis and cartilage17(3)321-7(2009 Mar)
Rodriguez-Lopez J,Pombo-Suarez M,Loughlin J,Tsezou A,Blanco FJ,Meulenbelt I,Slagboom PE,Valdes AM,Spector TD,Gomez-Reino JJ,Gonzalez A

Genetic association between polymorphisms in the ADAMTS14 gene and multiple sclerosis.
Journal of neuroimmunology164(1-2)140-7(2005 Jul)
Goertsches R,Comabella M,Navarro A,Perkal H,Montalban X

Cloning and characterization of ADAMTS-14, a novel ADAMTS displaying high homology with ADAMTS-2 and ADAMTS-3.
The Journal of biological chemistry277(8)5756-66(2002 Feb)
Colige A,Vandenberghe I,Thiry M,Lambert CA,Van Beeumen J,Li SW,Prockop DJ,Lapiere CM,Nusgens BV

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Adamts14 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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