Lama4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lama4
Entrez Gene ID	309816
Full Name	laminin subunit alpha 4
Synonyms	RGD1560062
General protein information	Preferred Names laminin subunit alpha 4 Names laminin subunit alpha-4 laminin, alpha 4
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 20 Map Location: 20q12

mRNA and Protein(s)

mRNA	Protein	Name
NM_001309447.1	NP_001296376.1	laminin subunit alpha-4 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	LAMA4	NP_001098676.2
	LAMA4	XP_002803983.1
Bos taurus (cattle)	LAMA4	NP_001192894.1
Danio rerio (zebrafish)	lama4	NP_001034154.1
Pan troglodytes (chimpanzee)	LAMA4	XP_518696.3
Canis lupus familiaris (dog)	LAMA4	XP_005627847.1
Rattus norvegicus (Norway rat)	Lama4	XP_003752023.1
Gallus gallus (chicken)	LAMA4	XP_004940355.1
Mus musculus (house mouse)	Lama4	NP_034811.2
Xenopus tropicalis (tropical clawed frog)	lama4	XP_002936983.2

Gene Ontology
Bibliography

Related articles in PubMed

The Absence of Laminin ?4 in Male Mice Results in Enhanced Energy Expenditure and Increased Beige Subcutaneous Adipose Tissue.
Vaicik MK, Blagajcevic A, Ye H, Morse MC, Yang F, Goddi A, Brey EM, Cohen RN
Endocrinology159(1)356-367(2018 Jan)

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.
Barallobre-Barreiro J, Gupta SK, Zoccarato A, Kitazume-Taneike R, Fava M, Yin X, Werner T, Hirt MN, Zampetaki A, Viviano A, Chong M, Bern M, Kourliouros A, Domenech N, Willeit P, Shah AM, Jahangiri M, Schaefer L, Fischer JW, Iozzo RV, Viner R, Thum T, Heineke J, Kichler A, Otsu K, Mayr M
Circulation134(11)817-32(2016 Sep)

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.
Barallobre-Barreiro J, Oklu R, Lynch M, Fava M, Baig F, Yin X, Barwari T, Potier DN, Albadawi H, Jahangiri M, Porter KE, Watkins MT, Misra S, Stoughton J, Mayr M
Cardiovascular research110(3)419-30(2016 06)

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Abonnenc M, Nabeebaccus AA, Mayr U, Barallobre-Barreiro J, Dong X, Cuello F, Sur S, Drozdov I, Langley SR, Lu R, Stathopoulou K, Didangelos A, Yin X, Zimmermann WH, Shah AM, Zampetaki A, Mayr M
Circulation research113(10)1138-47(2013 Oct)

Protein profile of exosomes from trabecular meshwork cells.
Stamer WD, Hoffman EA, Luther JM, Hachey DL, Schey KL
Journal of proteomics74(6)796-804(2011 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

synthesized by mesangial cells (MC) and persists in the mature glomerulus; suggested that laminin alpha4 plays an important role in MC differentiation and in the maintenance of MC phenotype.
Title: Laminin-8/9 is synthesized by rat glomerular mesangial cells and is required for PDGF-induced mesangial cell migration.

The following Lama4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lama4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa21287	NM_001309447.1 Latest version!	Rattus norvegicus laminin subunit alpha 4 (Lama4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$951.30 $1359.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lama4 ( NM_001309447.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001296376.1 Rattus norvegicus laminin subunit alpha 4 (Lama4), mRNA.

Price & Availability↑

CloneID	ORa21287
Clone ID Related Accession (Same CDS sequence)	NM_001309447.1
Accession Version	NM_001309447.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5454bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-07-06
Organism	Rattus norvegicus(Norway rat)
Product	laminin subunit alpha-4 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07045342.1, AABR07045344.1 and AABR07045345.1. On or before Jun 3, 2015 this sequence version replaced XM_003751975.3, XM_003753489.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FQ221747.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTTGGA ACACAGCCTG GTGCTCAGTC CTGGCCCTGT GGCTCCTCTG GGGTGCTGTC 
TGCTCCAACG CGGCGTCAGG GGACGGCAAT GCGTTTCCCT TTGACATCGA GGGGAGCGCA 
GTGGTCGGCA GGCAAGACCC ATCTGAGACC AGCGACTCCC GTGTGACAAT GGGACGCCTG 
CCGCCAGCTG CTGAGAGATG TGACGCCGGC TTCTTTCGCA CGTCATCAGG AGAATGTTCG 
CCCTGTGACT GTAACGGCAA TTCCCACGAG TGTTTGGATG GCTCCGGATT CTGTCTGCAC 
TGCCAGCGGA ACACAACAGG GGAGCACTGT GAAAGGTGTC TGGCTGGCTA TATTGGAGAC 
TCCATCAGAG GCGCACCCCG ATTCTGCCAG CCGTGCCCCT GTCCCTTACC TCACCTGGCC 
AACTTTGCAG AATCCTGCTT CAGGAAAAAC GGAGCTGTTC GGTGTATGTG TAAAGAAAAC 
TATGCTGGGC CTAACTGTGA AAGATGTGCT CCTGGTTACT ATGGAAACCC CCTACTCATC 
GGAAGCACCT GTAAGAAATG TGACTGCAGT GGCAATTCGG ATCCCAACCT CATCTTTGAA 
GACTGTGATG AAATCACTGG CCAGTGCAGG AACTGCTTAC GAAATACCAC CGGGTTCAAG 
TGTGAACGCT GTGCTCCTGG CTATTACGGG GATGCCAGGA TCGCCAAGAA CTGTGCAGTG 
TGCAACTGTG GGGGCGGCCC ATGTGACAGC GTAACCGGAG AGTGCTTGGA AGAAGGATTT 
GAACTCCCTA CAGGCTGTGA TAAGTGTGTC TGGGACTTGA CCGACGACCT GCGATTAGCA 
GCGCTCTCCA TCGAAGAGAG CAAATCCGGG CTGCTGAGCG TGTCCTCCGG CGCTGCGGCC 
CATAGACACG TGACCGACAT GAACTCTACC ATCCACCTCC TCAAAACAAG GTTGTCAGAA 
AGAGAAAACC AGTATACCCT GAGAAAGATC CAGATAAACA ACTCAGAGAA CACACTGAGA 
AGCCTCCTGT CTGACGTAGA GGAACTGGAT GAGAAGGGAA GCCGAGCCTC AAGGAAGGGG 
ACGCTGGTTG AAAAGGAAAG CACGGATACA ATTGACCAGG CAACTCAGCT CGTCGAGCAA 
GCCCACAGCA TGAGGGACAA AATCCAAGAA ATCAATAGCA AGATGCTTTA CTATGGAGAG 
AATCAGGAAC TTGGCCCTGA GGAAATTGCG GAGAAGCTGG TGTTGGCCCA GAAAATGCTG 
GATGAGATCC GAAGCCGGCA GCCATTCCTC ACCCATCGGG AGCTTGTGGA TGAGGAGGCA 
GATGAAGTCC AGGAATTGCT GAGCCAAGCT GAGAACTGGC AGAGACTGCA CAACGACACC 
CGCTCTTTAC TCCCTGTGGT GTTGGAGCAG CTGGATGACT ACAATGCTAA GCTGTCAGAC 
CTCCAGGAAT CCATTAACCA GGCCCTTGAC CATGTCAGGG ATGCAGAAGA CATGAACAGA 
GCCATCACCT CGAAGCAGCG GGACCATGAG AAACAACACG AGAGAGTGAA GGAACAGATG 
GAGGCCGTGG GCACCTCTCT GAGTTTGTCT GCAGACTCTC TCATCACACC TCGGCTCACT 
CTTGAGGAAC TTGATGAGAT AATAAAGAAT GCATCTGGAA TTTATGCAGA GATAGATGGA 
GCCAAAAACG AACTACAGGG GAAACTGTCC AACCTGAGTA ACCTCAGTCA TGATTTGGTC 
CAAGAAGCTG TGGACCACGC GTACAACCTC CAACAGGAAG CCAACGAGCT AAGCAGAAAT 
TTGCACAGTT CAGACATGAA TGGGCTGGTG CAGAAGGCTT TGGACGCATC CAATGTCTAT 
GAAAATATCG CCAACTATGT CAGTGAGGCC AACGAAACAG CAGAACTTGC TCTGAATATT 
ACTGATCGAA TTTATGACGC CGTGAGTGGA ATTGACACTC AGATCGTTTA CCATAAGGAT 
GAAAGCGACA ACCTTCTCAA TCAAGCCAGA GAGCTGCAAG CAAAGGCGGA TTCTAGCAGT 
GACGAGGCCG TGGCTGACAC CAGCAGGCGC GTGGGAGGAG CCCTGTGGAG GAAGGGCGCC 
CTCAGAGACA AACTGACCGA GGCTGTCAAG CAACTCCAGG CAGCAGAGAG AGGGGATGCC 
CACCAGCGCC TGGGCCAGAC TAAGCTCATC ATTGAGGAAG CTAACAAGAC GACAATGGCC 
GTCCAACAGG TCACCACACC GATGGCTAAC AACCTCAGCA ACTGGTCACA GAACCTTCAG 
ACTTTTGACT CTTCTGCCTA CAACACTGCA GTGAACTCCG CTCGGGACGC AGTGAGAAAC 
CTCACTGAGG TTGTTCCTCG GCTTCTGGGT CAGCTCCGTA CTGTGGAGCA GAAGCGGCCT 
GCAAGCAATG TTTCGGCCAG CATCCAGAGG GTCCGAGAGC TCATCGCTCA GACCAGGAGT 
GTTGCCAGCA AGATCCAGGT TTCCATGCTG TTCGATGGCC ACTCGGCCGT CGAAGTTCAC 
CCCAAAGTCA GTGTGGATGA CCTGAAGGCC TTCACCTCCA TCAGCTTGTA CATGAAGCCT 
CCTCCCAAGC CGGCGGAGCC CACCGGGGCC TGGGTAGAAG ATCAGTTTGT CCTCTACCTC 
GGAAGCAAAA CCGCCAAAAA AGAGTACATG GGTCTGGCAA TCAAAAATGA TAACCTGGTC 
TACGTTTACA ATTTGGGGAC CAAAGATGTG GAGATTCTCC TGGATTCCAA GCCCGTGAGC 
TCCTGGCCTG CTTACTTTAG TATTGTCAAG ATTGAGAGGG TAGGGAAACA TGGAAAGGTG 
TTCTTGACAG TCCCCAGTCT CAGCAGCACA GCAGAAGAAA AGTTTATTAA GAAGGGGGAG 
TTTGCAGGAG ACGACTCCTT GCTGGATCTG ACCCCTGAGG ATACTGTGTT TTACGTTGGC 
GGGGTTCCTG CAAACTTCAA GCTCCCGGCC AGCTTAAACC TGCCCAGCTA CTCAGGCTGC 
CTGGAGCTGG CCACTCTGAA TAATGATGTA ATCAGCCTGT ACAACTTCAA GCACATCTAC 
AACATGGACC CAGCTAAGTC GGTGCCCTGT GCCAGGGATA AACTGGCTTT CACTCAGAGC 
AGGGCTGCCA GCTACTTCTT CGATGGCTCC AGTTACGCTG TGGTGAGGGA CATCACCAGG 
AGAGGGAAAT TTGGCCAGGT GACTCGCTTT GACATAGAGA TTCGAACACC AGCTGACAAT 
GGCCTCGTGC TCCTGATGGT CAATGGAAGT ATGTTTTTCA GCCTGGAAAT GCGCAATGGC 
TACCTGCATG TGTTCTACGA CTTTGGATTC AGCAACGGAC CCGTGCATCT TGAAGACACA 
TTGAAAAAGG CCCAGATCAA CGATGCGAAA TACCATGAGA TCTCAATCAT TTACCACAAT 
GACAAGAAAA TGATTTTGGT GGTGGACAGA CGGCATGTTA AGAGCACAGA CAATGAGAAG 
AAGAAGATAC CATTCACAGA CATCTACATT GGAGGTGCGC CCCAAGAAGT CTTACAGTCC 
AGGACCCTAA GAGCACATCT TCCCCTAGAC ATCAACTTTA GGGGATGCAT GAAGGGTTTC 
CAGTTCCAAA AGAAAGATTT CAATTTACTG GAGCAGAAAG AAACCTTAGG AGTTGGTTAT 
GGATGCCCAG AGGACTCCCT GATCTCTCGC AGAGCATATT TCAACGGGCA AAGTTTTATT 
GCTTCAACTC AGAAAATATC TTTCTTCGAT GGCTTCGAAG GAGGCTTCAA TTTCCGAACG 
TTACAGCCAA ATGGGTTACT GTTCTACTAT GCCTCTGGGT CCGACGATGT GTTTTCCATT 
TCCCTGGACA ATGGCACTGT CGTCATGGAT GTAAAGGGCA TCAAGGTAAA GTCAGCAGAC 
AAGCAGTACC ATGATGGGCT GTCCCACTTC GTCGTCACCA CCGTCTCAGC CACAAGGTAT 
GAACTAGTAG TAGACAAAAG CCGACTTGGG AGTAAGAATC CTACGAAAGG GAAGGCAGAG 
CCGACGCAAA CAACCGAGAA GAAGTTCTAC TTCGGTGGCT CGCCCATCAG CCCTCAGTAT 
GCTAATTTCA CTGGATGTAT AAGCAATGCC TACTTTACCA GGTTGGATAG AGATGTGGAA 
GTTGAAGATT TCCAGCGGTA TTCTGAAAAG GTGCACACTT CACTCTATGA GTGTCCCATC 
GAGTCGTCAC CTCTGTTTCT CCTTCACAAA AAAGGAAAGA ATTCCTCAAA GCCTAAAACA 
AACAAACAGG GAGAGAAAAG TAAGGACGCA CCTTCGTGGG ATCCTATTGG TCTGAAGTTT 
CTGGAACGGA AAGCCTCAAG AGACTCCCAC TGCCACCTCT CCAGCAGCCC CAGAGCGATA 
GAGCATGCCT ATCAATATGG CGGCACGGCC AACAGCCGCC AAGAGTTTGA ACACATACAA 
GGAGATTTTG GTGAAAAATC CCAGTTTGCC ATTCGTCTGA AGACCCGTTC CTCACATGGG 
ATGATTTTCT ATGTCTCAGA CCAAGAAGAG AATGATTTCA TGACCCTGTT CTTGGCCCAC 
GGTCGCTTGG TCTTTATGTT TAATGTCGGC CACAAGAAAC TGAAGATTAG AAGCCAGGAG 
AAGTACAGTG ATGGGTTGTG GCATGATGTG ATATTTATTC GGGAAAAGAG CAGTGGCCGA 
TTGGTCATTG ATGGTCTGCG AGTCCTCGAA GAAAGGCTCC CCCCTAGTGA CGCTGCCTGG 
AAAATCAAGG GTCCCATTTA TCTGGGAGGA GTGGCTCCCG GAAGGGCTGT GAAAAATGTC 
CAGATTAACT CAGTCTACAG TTTCAGTGGC TGCCTTGGCA ATCTCCAGCT CAATGGAGCC 
TCCATCGCCT CTGCCTCCCA AACGTTTAGC GTGACCCCTT GCTTTGAAGG GCCAATGGAG 
ACGGGGACTT ATTTCTCCAC AGAAGGAGGC TATGTGGTTC TAGATGAGTC TTTCAACATT 
GGGCTAAAGT TTGAAATCGC ATTTGAAGTC CGTCCCCGGA GCAGTTCCGG GACCCTTGTC 
CATGGCCACA GTGTCAACGG GGAATACCTG AACGTACACA TGAAAAGCGG ACAGGTCATA 
GTGAAAGTCA ACAATGGCGT CAGAGACTTT TCTACCTCAG TCACCCCCAA GCAGAATCTC 
TGCGATGGCA GATGGCACAG AATTACAGTT ATTAGAGACT CCAACGTGGT TCAGTTGGAT 
GTAGATTCAG AGGTGAACCA TGTAGTTGGA CCCCTGAACC CAAAGCCGGT TGATCACAGG 
GAGCCTGTGT TTGTCGGAGG GGTTCCAGAG TCCTTGCTGA CGCCCCGTTT GACTCCCAGC 
AAACCCTTCA CAGGCTGCAT CCGTCACTTT GTGATCGATG GGCGTCCGGT GAGCTTCAGT 
AAAGCAGCCC TGGTCAGTGG TGCTGTGAGC ATTAACTCCT GCCCCACAGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001296376.1
CDS	445..5898
Translation	MAWNTAWCSVLALWLLWGAVCSNAASGDGNAFPFDIEGSAVVGRQDPSETSDSRVTMGRLPPAAERCDAGFFRTSSGECSPCDCNGNSHECLDGSGFCLHCQRNTTGEHCERCLAGYIGDSIRGAPRFCQPCPCPLPHLANFAESCFRKNGAVRCMCKENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEITGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFELPTGCDKCVWDLTDDLRLAALSIEESKSGLLSVSSGAAAHRHVTDMNSTIHLLKTRLSERENQYTLRKIQINNSENTLRSLLSDVEELDEKGSRASRKGTLVEKESTDTIDQATQLVEQAHSMRDKIQEINSKMLYYGENQELGPEEIAEKLVLAQKMLDEIRSRQPFLTHRELVDEEADEVQELLSQAENWQRLHNDTRSLLPVVLEQLDDYNAKLSDLQESINQALDHVRDAEDMNRAITSKQRDHEKQHERVKEQMEAVGTSLSLSADSLITPRLTLEELDEIIKNASGIYAEIDGAKNELQGKLSNLSNLSHDLVQEAVDHAYNLQQEANELSRNLHSSDMNGLVQKALDASNVYENIANYVSEANETAELALNITDRIYDAVSGIDTQIVYHKDESDNLLNQARELQAKADSSSDEAVADTSRRVGGALWRKGALRDKLTEAVKQLQAAERGDAHQRLGQTKLIIEEANKTTMAVQQVTTPMANNLSNWSQNLQTFDSSAYNTAVNSARDAVRNLTEVVPRLLGQLRTVEQKRPASNVSASIQRVRELIAQTRSVASKIQVSMLFDGHSAVEVHPKVSVDDLKAFTSISLYMKPPPKPAEPTGAWVEDQFVLYLGSKTAKKEYMGLAIKNDNLVYVYNLGTKDVEILLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFAGDDSLLDLTPEDTVFYVGGVPANFKLPASLNLPSYSGCLELATLNNDVISLYNFKHIYNMDPAKSVPCARDKLAFTQSRAASYFFDGSSYAVVRDITRRGKFGQVTRFDIEIRTPADNGLVLLMVNGSMFFSLEMRNGYLHVFYDFGFSNGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSTDNEKKKIPFTDIYIGGAPQEVLQSRTLRAHLPLDINFRGCMKGFQFQKKDFNLLEQKETLGVGYGCPEDSLISRRAYFNGQSFIASTQKISFFDGFEGGFNFRTLQPNGLLFYYASGSDDVFSISLDNGTVVMDVKGIKVKSADKQYHDGLSHFVVTTVSATRYELVVDKSRLGSKNPTKGKAEPTQTTEKKFYFGGSPISPQYANFTGCISNAYFTRLDRDVEVEDFQRYSEKVHTSLYECPIESSPLFLLHKKGKNSSKPKTNKQGEKSKDAPSWDPIGLKFLERKASRDSHCHLSSSPRAIEHAYQYGGTANSRQEFEHIQGDFGEKSQFAIRLKTRSSHGMIFYVSDQEENDFMTLFLAHGRLVFMFNVGHKKLKIRSQEKYSDGLWHDVIFIREKSSGRLVIDGLRVLEERLPPSDAAWKIKGPIYLGGVAPGRAVKNVQINSVYSFSGCLGNLQLNGASIASASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMKSGQVIVKVNNGVRDFSTSVTPKQNLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPVDHREPVFVGGVPESLLTPRLTPSKPFTGCIRHFVIDGRPVSFSKAALVSGAVSINSCPTA

Target ORF information:

RefSeq Version	NM_001309447.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus laminin subunit alpha 4 (Lama4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001309447.1

ORF Insert Sequence:

ATGGCTTGGA ACACAGCCTG GTGCTCAGTC CTGGCCCTGT GGCTCCTCTG GGGTGCTGTC 
TGCTCCAACG CGGCGTCAGG GGACGGCAAT GCGTTTCCCT TTGACATCGA GGGGAGCGCA 
GTGGTCGGCA GGCAAGACCC ATCTGAGACC AGCGACTCCC GTGTGACAAT GGGACGCCTG 
CCGCCAGCTG CTGAGAGATG TGACGCCGGC TTCTTTCGCA CGTCATCAGG AGAATGTTCG 
CCCTGTGACT GTAACGGCAA TTCCCACGAG TGTTTGGATG GCTCCGGATT CTGTCTGCAC 
TGCCAGCGGA ACACAACAGG GGAGCACTGT GAAAGGTGTC TGGCTGGCTA TATTGGAGAC 
TCCATCAGAG GCGCACCCCG ATTCTGCCAG CCGTGCCCCT GTCCCTTACC TCACCTGGCC 
AACTTTGCAG AATCCTGCTT CAGGAAAAAC GGAGCTGTTC GGTGTATGTG TAAAGAAAAC 
TATGCTGGGC CTAACTGTGA AAGATGTGCT CCTGGTTACT ATGGAAACCC CCTACTCATC 
GGAAGCACCT GTAAGAAATG TGACTGCAGT GGCAATTCGG ATCCCAACCT CATCTTTGAA 
GACTGTGATG AAATCACTGG CCAGTGCAGG AACTGCTTAC GAAATACCAC CGGGTTCAAG 
TGTGAACGCT GTGCTCCTGG CTATTACGGG GATGCCAGGA TCGCCAAGAA CTGTGCAGTG 
TGCAACTGTG GGGGCGGCCC ATGTGACAGC GTAACCGGAG AGTGCTTGGA AGAAGGATTT 
GAACTCCCTA CAGGCTGTGA TAAGTGTGTC TGGGACTTGA CCGACGACCT GCGATTAGCA 
GCGCTCTCCA TCGAAGAGAG CAAATCCGGG CTGCTGAGCG TGTCCTCCGG CGCTGCGGCC 
CATAGACACG TGACCGACAT GAACTCTACC ATCCACCTCC TCAAAACAAG GTTGTCAGAA 
AGAGAAAACC AGTATACCCT GAGAAAGATC CAGATAAACA ACTCAGAGAA CACACTGAGA 
AGCCTCCTGT CTGACGTAGA GGAACTGGAT GAGAAGGGAA GCCGAGCCTC AAGGAAGGGG 
ACGCTGGTTG AAAAGGAAAG CACGGATACA ATTGACCAGG CAACTCAGCT CGTCGAGCAA 
GCCCACAGCA TGAGGGACAA AATCCAAGAA ATCAATAGCA AGATGCTTTA CTATGGAGAG 
AATCAGGAAC TTGGCCCTGA GGAAATTGCG GAGAAGCTGG TGTTGGCCCA GAAAATGCTG 
GATGAGATCC GAAGCCGGCA GCCATTCCTC ACCCATCGGG AGCTTGTGGA TGAGGAGGCA 
GATGAAGTCC AGGAATTGCT GAGCCAAGCT GAGAACTGGC AGAGACTGCA CAACGACACC 
CGCTCTTTAC TCCCTGTGGT GTTGGAGCAG CTGGATGACT ACAATGCTAA GCTGTCAGAC 
CTCCAGGAAT CCATTAACCA GGCCCTTGAC CATGTCAGGG ATGCAGAAGA CATGAACAGA 
GCCATCACCT CGAAGCAGCG GGACCATGAG AAACAACACG AGAGAGTGAA GGAACAGATG 
GAGGCCGTGG GCACCTCTCT GAGTTTGTCT GCAGACTCTC TCATCACACC TCGGCTCACT 
CTTGAGGAAC TTGATGAGAT AATAAAGAAT GCATCTGGAA TTTATGCAGA GATAGATGGA 
GCCAAAAACG AACTACAGGG GAAACTGTCC AACCTGAGTA ACCTCAGTCA TGATTTGGTC 
CAAGAAGCTG TGGACCACGC GTACAACCTC CAACAGGAAG CCAACGAGCT AAGCAGAAAT 
TTGCACAGTT CAGACATGAA TGGGCTGGTG CAGAAGGCTT TGGACGCATC CAATGTCTAT 
GAAAATATCG CCAACTATGT CAGTGAGGCC AACGAAACAG CAGAACTTGC TCTGAATATT 
ACTGATCGAA TTTATGACGC CGTGAGTGGA ATTGACACTC AGATCGTTTA CCATAAGGAT 
GAAAGCGACA ACCTTCTCAA TCAAGCCAGA GAGCTGCAAG CAAAGGCGGA TTCTAGCAGT 
GACGAGGCCG TGGCTGACAC CAGCAGGCGC GTGGGAGGAG CCCTGTGGAG GAAGGGCGCC 
CTCAGAGACA AACTGACCGA GGCTGTCAAG CAACTCCAGG CAGCAGAGAG AGGGGATGCC 
CACCAGCGCC TGGGCCAGAC TAAGCTCATC ATTGAGGAAG CTAACAAGAC GACAATGGCC 
GTCCAACAGG TCACCACACC GATGGCTAAC AACCTCAGCA ACTGGTCACA GAACCTTCAG 
ACTTTTGACT CTTCTGCCTA CAACACTGCA GTGAACTCCG CTCGGGACGC AGTGAGAAAC 
CTCACTGAGG TTGTTCCTCG GCTTCTGGGT CAGCTCCGTA CTGTGGAGCA GAAGCGGCCT 
GCAAGCAATG TTTCGGCCAG CATCCAGAGG GTCCGAGAGC TCATCGCTCA GACCAGGAGT 
GTTGCCAGCA AGATCCAGGT TTCCATGCTG TTCGATGGCC ACTCGGCCGT CGAAGTTCAC 
CCCAAAGTCA GTGTGGATGA CCTGAAGGCC TTCACCTCCA TCAGCTTGTA CATGAAGCCT 
CCTCCCAAGC CGGCGGAGCC CACCGGGGCC TGGGTAGAAG ATCAGTTTGT CCTCTACCTC 
GGAAGCAAAA CCGCCAAAAA AGAGTACATG GGTCTGGCAA TCAAAAATGA TAACCTGGTC 
TACGTTTACA ATTTGGGGAC CAAAGATGTG GAGATTCTCC TGGATTCCAA GCCCGTGAGC 
TCCTGGCCTG CTTACTTTAG TATTGTCAAG ATTGAGAGGG TAGGGAAACA TGGAAAGGTG 
TTCTTGACAG TCCCCAGTCT CAGCAGCACA GCAGAAGAAA AGTTTATTAA GAAGGGGGAG 
TTTGCAGGAG ACGACTCCTT GCTGGATCTG ACCCCTGAGG ATACTGTGTT TTACGTTGGC 
GGGGTTCCTG CAAACTTCAA GCTCCCGGCC AGCTTAAACC TGCCCAGCTA CTCAGGCTGC 
CTGGAGCTGG CCACTCTGAA TAATGATGTA ATCAGCCTGT ACAACTTCAA GCACATCTAC 
AACATGGACC CAGCTAAGTC GGTGCCCTGT GCCAGGGATA AACTGGCTTT CACTCAGAGC 
AGGGCTGCCA GCTACTTCTT CGATGGCTCC AGTTACGCTG TGGTGAGGGA CATCACCAGG 
AGAGGGAAAT TTGGCCAGGT GACTCGCTTT GACATAGAGA TTCGAACACC AGCTGACAAT 
GGCCTCGTGC TCCTGATGGT CAATGGAAGT ATGTTTTTCA GCCTGGAAAT GCGCAATGGC 
TACCTGCATG TGTTCTACGA CTTTGGATTC AGCAACGGAC CCGTGCATCT TGAAGACACA 
TTGAAAAAGG CCCAGATCAA CGATGCGAAA TACCATGAGA TCTCAATCAT TTACCACAAT 
GACAAGAAAA TGATTTTGGT GGTGGACAGA CGGCATGTTA AGAGCACAGA CAATGAGAAG 
AAGAAGATAC CATTCACAGA CATCTACATT GGAGGTGCGC CCCAAGAAGT CTTACAGTCC 
AGGACCCTAA GAGCACATCT TCCCCTAGAC ATCAACTTTA GGGGATGCAT GAAGGGTTTC 
CAGTTCCAAA AGAAAGATTT CAATTTACTG GAGCAGAAAG AAACCTTAGG AGTTGGTTAT 
GGATGCCCAG AGGACTCCCT GATCTCTCGC AGAGCATATT TCAACGGGCA AAGTTTTATT 
GCTTCAACTC AGAAAATATC TTTCTTCGAT GGCTTCGAAG GAGGCTTCAA TTTCCGAACG 
TTACAGCCAA ATGGGTTACT GTTCTACTAT GCCTCTGGGT CCGACGATGT GTTTTCCATT 
TCCCTGGACA ATGGCACTGT CGTCATGGAT GTAAAGGGCA TCAAGGTAAA GTCAGCAGAC 
AAGCAGTACC ATGATGGGCT GTCCCACTTC GTCGTCACCA CCGTCTCAGC CACAAGGTAT 
GAACTAGTAG TAGACAAAAG CCGACTTGGG AGTAAGAATC CTACGAAAGG GAAGGCAGAG 
CCGACGCAAA CAACCGAGAA GAAGTTCTAC TTCGGTGGCT CGCCCATCAG CCCTCAGTAT 
GCTAATTTCA CTGGATGTAT AAGCAATGCC TACTTTACCA GGTTGGATAG AGATGTGGAA 
GTTGAAGATT TCCAGCGGTA TTCTGAAAAG GTGCACACTT CACTCTATGA GTGTCCCATC 
GAGTCGTCAC CTCTGTTTCT CCTTCACAAA AAAGGAAAGA ATTCCTCAAA GCCTAAAACA 
AACAAACAGG GAGAGAAAAG TAAGGACGCA CCTTCGTGGG ATCCTATTGG TCTGAAGTTT 
CTGGAACGGA AAGCCTCAAG AGACTCCCAC TGCCACCTCT CCAGCAGCCC CAGAGCGATA 
GAGCATGCCT ATCAATATGG CGGCACGGCC AACAGCCGCC AAGAGTTTGA ACACATACAA 
GGAGATTTTG GTGAAAAATC CCAGTTTGCC ATTCGTCTGA AGACCCGTTC CTCACATGGG 
ATGATTTTCT ATGTCTCAGA CCAAGAAGAG AATGATTTCA TGACCCTGTT CTTGGCCCAC 
GGTCGCTTGG TCTTTATGTT TAATGTCGGC CACAAGAAAC TGAAGATTAG AAGCCAGGAG 
AAGTACAGTG ATGGGTTGTG GCATGATGTG ATATTTATTC GGGAAAAGAG CAGTGGCCGA 
TTGGTCATTG ATGGTCTGCG AGTCCTCGAA GAAAGGCTCC CCCCTAGTGA CGCTGCCTGG 
AAAATCAAGG GTCCCATTTA TCTGGGAGGA GTGGCTCCCG GAAGGGCTGT GAAAAATGTC 
CAGATTAACT CAGTCTACAG TTTCAGTGGC TGCCTTGGCA ATCTCCAGCT CAATGGAGCC 
TCCATCGCCT CTGCCTCCCA AACGTTTAGC GTGACCCCTT GCTTTGAAGG GCCAATGGAG 
ACGGGGACTT ATTTCTCCAC AGAAGGAGGC TATGTGGTTC TAGATGAGTC TTTCAACATT 
GGGCTAAAGT TTGAAATCGC ATTTGAAGTC CGTCCCCGGA GCAGTTCCGG GACCCTTGTC 
CATGGCCACA GTGTCAACGG GGAATACCTG AACGTACACA TGAAAAGCGG ACAGGTCATA 
GTGAAAGTCA ACAATGGCGT CAGAGACTTT TCTACCTCAG TCACCCCCAA GCAGAATCTC 
TGCGATGGCA GATGGCACAG AATTACAGTT ATTAGAGACT CCAACGTGGT TCAGTTGGAT 
GTAGATTCAG AGGTGAACCA TGTAGTTGGA CCCCTGAACC CAAAGCCGGT TGATCACAGG 
GAGCCTGTGT TTGTCGGAGG GGTTCCAGAG TCCTTGCTGA CGCCCCGTTT GACTCCCAGC 
AAACCCTTCA CAGGCTGCAT CCGTCACTTT GTGATCGATG GGCGTCCGGT GAGCTTCAGT 
AAAGCAGCCC TGGTCAGTGG TGCTGTGAGC ATTAACTCCT GCCCCACAGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The Absence of Laminin ?4 in Male Mice Results in Enhanced Energy Expenditure and Increased Beige Subcutaneous Adipose Tissue.
Endocrinology159(1)356-367(2018 Jan)
Vaicik MK,Blagajcevic A,Ye H,Morse MC,Yang F,Goddi A,Brey EM,Cohen RN

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.
Circulation134(11)817-32(2016 Sep)
Barallobre-Barreiro J,Gupta SK,Zoccarato A,Kitazume-Taneike R,Fava M,Yin X,Werner T,Hirt MN,Zampetaki A,Viviano A,Chong M,Bern M,Kourliouros A,Domenech N,Willeit P,Shah AM,Jahangiri M,Schaefer L,Fischer JW,Iozzo RV,Viner R,Thum T,Heineke J,Kichler A,Otsu K,Mayr M

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.
Cardiovascular research110(3)419-30(2016 06)
Barallobre-Barreiro J,Oklu R,Lynch M,Fava M,Baig F,Yin X,Barwari T,Potier DN,Albadawi H,Jahangiri M,Porter KE,Watkins MT,Misra S,Stoughton J,Mayr M

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Circulation research113(10)1138-47(2013 Oct)
Abonnenc M,Nabeebaccus AA,Mayr U,Barallobre-Barreiro J,Dong X,Cuello F,Sur S,Drozdov I,Langley SR,Lu R,Stathopoulou K,Didangelos A,Yin X,Zimmermann WH,Shah AM,Zampetaki A,Mayr M

Protein profile of exosomes from trabecular meshwork cells.
Journal of proteomics74(6)796-804(2011 May)
Stamer WD,Hoffman EA,Luther JM,Hachey DL,Schey KL

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Lama4 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

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