Rom1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Rom1
Entrez Gene ID	309201
Full Name	retinal outer segment membrane protein 1
General protein information	Preferred Names retinal outer segment membrane protein 1 Names rod outer segment membrane protein 1 ROSP1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q43

mRNA and Protein(s)

mRNA	Protein	Name
NM_001009690.1	NP_001009690.1	rod outer segment membrane protein 1

Pathways from BioSystems

Homologies

	ROM1	XP_002799528.1
Bos taurus (cattle)	ROM1	NP_776599.2
Mus musculus (house mouse)	Rom1	NP_033099.3
Canis lupus familiaris (dog)	ROM1	XP_540907.3
Homo sapiens (human)	ROM1	NP_000318.1
Pan troglodytes (chimpanzee)	ROM1	XP_001142314.3
Rattus norvegicus (Norway rat)	Rom1	NP_001009690.1

Gene Ontology
Bibliography

Related articles in PubMed

Tulp1 is involved in specific photoreceptor protein transport pathways.
Hagstrom SA, Watson RF, Pauer GJ, Grossman GH
Advances in experimental medicine and biology723783-9(2012)

Retinal degeneration and failure of photoreceptor outer segment formation in mice with targeted deletion of the Joubert syndrome gene, Ahi1.
Westfall JE, Hoyt C, Liu Q, Hsiao YC, Pierce EA, Page-McCaw PS, Ferland RJ
The Journal of neuroscience : the official journal of the Society for Neuroscience30(26)8759-68(2010 Jun)

A monogenic dominant mutation in Rom1 generated by N-ethyl-N-nitrosourea mutagenesis causes retinal degeneration in mice.
Sato H, Suzuki T, Ikeda K, Masuya H, Sezutsu H, Kaneda H, Kobayashi K, Miura I, Kurihara Y, Yokokura S, Nishida K, Tamai M, Gondo Y, Noda T, Wakana S
Molecular vision16378-91(2010 Mar)

Mutant prominin 1 found in patients with macular degeneration disrupts photoreceptor disk morphogenesis in mice.
Yang Z, Chen Y, Lillo C, Chien J, Yu Z, Michaelides M, Klein M, Howes KA, Li Y, Kaminoh Y, Chen H, Zhao C, Chen Y, Al-Sheikh YT, Karan G, Corbeil D, Escher P, Kamaya S, Li C, Johnson S, Frederick JM, Zhao Y, Wang C, Cameron DJ, Huttner WB, Schorderet DF, Munier FL, Moore AT, Birch DG, Baehr W, Hunt DM, Williams DS, Zhang K
The Journal of clinical investigation118(8)2908-16(2008 Aug)

Rom-1 is required for rod photoreceptor viability and the regulation of disk morphogenesis.
Clarke G, Goldberg AF, Vidgen D, Collins L, Ploder L, Schwarz L, Molday LL, Rossant J, Sz?l A, Molday RS, Birch DG, McInnes RR
Nature genetics25(1)67-73(2000 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Rom1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rom1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa00853	NM_001009690.1 Latest version!	Rattus norvegicus retinal outer segment membrane protein 1 (Rom1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Rom1 ( NM_001009690.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001009690.1 Rattus norvegicus retinal outer segment membrane protein 1 (Rom1), mRNA.

Price & Availability↑

CloneID	ORa00853
Clone ID Related Accession (Same CDS sequence)	NM_001009690.1
Accession Version	NM_001009690.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1056bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Rattus norvegicus(Norway rat)
Product	rod outer segment membrane protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC087605.1. On Jan 13, 2005 this sequence version replaced XM_219564.2. ##Evidence-Data-START## Transcript exon combination :: BC087605.1, CA997766.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGCGCCGG TGCTGCCCGT GGTGCTGCCC CTCCAACCCC GTATCCGTTT GGCACAGGGG 
ACCTGGCTCC TCTCCTGGCT ACTGGCACTA GCCGGTGGCC TCACCCTCCT CTGTAGTGGG 
CACCTCCTGG TACAGCTGTG GCACCTTGGC ACCTTCCTGG CTCCCTCTTG TTCATTCCCT 
GCCCTGCCCC AGACTGCCCT GGCGGCAGGA GCAGTGGCAT TAGGCACAGG GCTAGGAGGT 
GCAGGAGCCA GCCGGGCGAG CCTGGATGCA GCTCAATACC CTCCCTGGCG AGGGGTCCTG 
ACTCCACTGC TAGTGGTTGG CACTGCTGCA GGTGGGGGGC TGCTGACCCT TGGTCTGGGG 
CTAGCCCTGG CCTTGCCTGT AAGTCTCCAC CAGGGACTGG AAGAGGGCCT GCAGGCTGCC 
TTGGCTCACT ACAAGGATAC AGAGGTGCCT GGACACTGTC AGGCCAAACG ACTGATGGAT 
GAATTGCAGC TGAGGTACCA TTGCTGTGGG CGCCATGGCT ACAAGGATTG GTTTGGTGTT 
CAGTGGGTCA GCAGCCGTTA CCTGGACCCC AATGACCAAG ATGTGGTTGA CCGGATCCAG 
AGCAACGTGG AAGGTTTATA TCTGATTGAT GGAGTGCCCT TCTCCTGTTG TAACCCCCAC 
TCACCCCGGC CCTGCCTGCA AAGCCAGCTC TCAGACCCCT ATGCCCATCC ACTCTTCGAT 
CCTCGGCAGC CCAACCTAAA CCTGTGGGCC CAAGGGTGCC ACGAAGTGCT CGTGGGGCAC 
CTGCAGGGTT TGTCCGGCAC ACTGGGAAGT ATTCTGGCTG TCACCTTATT GCTGCAGGTT 
CTTGTGCTCC TTGGTTTGCG GTATTTGCAG ACAGCGCTGG AAGGCCTTGG AGGAGTCATT 
GATGGGGAAG GAGAGACCCA GGGCTATCTT TTGCCTGGTG GGCTGAAAGA CATACTGCAA 
ACTGCATGGC TACAGGGAGG GCTTGCCCAC AAGCCAGCAC CTGAGGAGGC CCCACCAGAT 
GAGGAACCTC CCAAGGAAGT TCTAGCTGAG GCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001009690.1
CDS	217..1272
Translation	MAPVLPVVLPLQPRIRLAQGTWLLSWLLALAGGLTLLCSGHLLVQLWHLGTFLAPSCSFPALPQTALAAGAVALGTGLGGAGASRASLDAAQYPPWRGVLTPLLVVGTAAGGGLLTLGLGLALALPVSLHQGLEEGLQAALAHYKDTEVPGHCQAKRLMDELQLRYHCCGRHGYKDWFGVQWVSSRYLDPNDQDVVDRIQSNVEGLYLIDGVPFSCCNPHSPRPCLQSQLSDPYAHPLFDPRQPNLNLWAQGCHEVLVGHLQGLSGTLGSILAVTLLLQVLVLLGLRYLQTALEGLGGVIDGEGETQGYLLPGGLKDILQTAWLQGGLAHKPAPEEAPPDEEPPKEVLAEA

Target ORF information:

RefSeq Version	NM_001009690.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus retinal outer segment membrane protein 1 (Rom1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001009690.1

ORF Insert Sequence:

ATGGCGCCGG TGCTGCCCGT GGTGCTGCCC CTCCAACCCC GTATCCGTTT GGCACAGGGG 
ACCTGGCTCC TCTCCTGGCT ACTGGCACTA GCCGGTGGCC TCACCCTCCT CTGTAGTGGG 
CACCTCCTGG TACAGCTGTG GCACCTTGGC ACCTTCCTGG CTCCCTCTTG TTCATTCCCT 
GCCCTGCCCC AGACTGCCCT GGCGGCAGGA GCAGTGGCAT TAGGCACAGG GCTAGGAGGT 
GCAGGAGCCA GCCGGGCGAG CCTGGATGCA GCTCAATACC CTCCCTGGCG AGGGGTCCTG 
ACTCCACTGC TAGTGGTTGG CACTGCTGCA GGTGGGGGGC TGCTGACCCT TGGTCTGGGG 
CTAGCCCTGG CCTTGCCTGT AAGTCTCCAC CAGGGACTGG AAGAGGGCCT GCAGGCTGCC 
TTGGCTCACT ACAAGGATAC AGAGGTGCCT GGACACTGTC AGGCCAAACG ACTGATGGAT 
GAATTGCAGC TGAGGTACCA TTGCTGTGGG CGCCATGGCT ACAAGGATTG GTTTGGTGTT 
CAGTGGGTCA GCAGCCGTTA CCTGGACCCC AATGACCAAG ATGTGGTTGA CCGGATCCAG 
AGCAACGTGG AAGGTTTATA TCTGATTGAT GGAGTGCCCT TCTCCTGTTG TAACCCCCAC 
TCACCCCGGC CCTGCCTGCA AAGCCAGCTC TCAGACCCCT ATGCCCATCC ACTCTTCGAT 
CCTCGGCAGC CCAACCTAAA CCTGTGGGCC CAAGGGTGCC ACGAAGTGCT CGTGGGGCAC 
CTGCAGGGTT TGTCCGGCAC ACTGGGAAGT ATTCTGGCTG TCACCTTATT GCTGCAGGTT 
CTTGTGCTCC TTGGTTTGCG GTATTTGCAG ACAGCGCTGG AAGGCCTTGG AGGAGTCATT 
GATGGGGAAG GAGAGACCCA GGGCTATCTT TTGCCTGGTG GGCTGAAAGA CATACTGCAA 
ACTGCATGGC TACAGGGAGG GCTTGCCCAC AAGCCAGCAC CTGAGGAGGC CCCACCAGAT 
GAGGAACCTC CCAAGGAAGT TCTAGCTGAG GCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Tulp1 is involved in specific photoreceptor protein transport pathways.
Advances in experimental medicine and biology723783-9(2012)
Hagstrom SA,Watson RF,Pauer GJ,Grossman GH

Retinal degeneration and failure of photoreceptor outer segment formation in mice with targeted deletion of the Joubert syndrome gene, Ahi1.
The Journal of neuroscience : the official journal of the Society for Neuroscience30(26)8759-68(2010 Jun)
Westfall JE,Hoyt C,Liu Q,Hsiao YC,Pierce EA,Page-McCaw PS,Ferland RJ

A monogenic dominant mutation in Rom1 generated by N-ethyl-N-nitrosourea mutagenesis causes retinal degeneration in mice.
Molecular vision16378-91(2010 Mar)
Sato H,Suzuki T,Ikeda K,Masuya H,Sezutsu H,Kaneda H,Kobayashi K,Miura I,Kurihara Y,Yokokura S,Nishida K,Tamai M,Gondo Y,Noda T,Wakana S

Mutant prominin 1 found in patients with macular degeneration disrupts photoreceptor disk morphogenesis in mice.
The Journal of clinical investigation118(8)2908-16(2008 Aug)
Yang Z,Chen Y,Lillo C,Chien J,Yu Z,Michaelides M,Klein M,Howes KA,Li Y,Kaminoh Y,Chen H,Zhao C,Chen Y,Al-Sheikh YT,Karan G,Corbeil D,Escher P,Kamaya S,Li C,Johnson S,Frederick JM,Zhao Y,Wang C,Cameron DJ,Huttner WB,Schorderet DF,Munier FL,Moore AT,Birch DG,Baehr W,Hunt DM,Williams DS,Zhang K

Rom-1 is required for rod photoreceptor viability and the regulation of disk morphogenesis.
Nature genetics25(1)67-73(2000 May)
Clarke G,Goldberg AF,Vidgen D,Collins L,Ploder L,Schwarz L,Molday LL,Rossant J,Sz?l A,Molday RS,Birch DG,McInnes RR

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Rom1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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