Fermt3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Fermt3
Entrez Gene ID	309186
Full Name	fermitin family member 3
Synonyms	RGD1310168
General protein information	Preferred Names fermitin family member 3 Names fermitin family homolog 3
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q43

mRNA and Protein(s)

mRNA	Protein	Name
XM_006230811.3	XP_006230873.1	fermitin family homolog 3 isoform X1
NM_001127543.1	NP_001121015.1	fermitin family homolog 3

Pathways from BioSystems

Homologies

Homo sapiens (human)	FERMT3	NP_848537.1
	LOC722120	XP_001118313.2
Canis lupus familiaris (dog)	FERMT3	XP_003639703.1
Mus musculus (house mouse)	Fermt3	NP_722490.1
Pan troglodytes (chimpanzee)	FERMT3	XP_508522.3
Rattus norvegicus (Norway rat)	Fermt3	NP_001121015.1
Danio rerio (zebrafish)	fermt3b	NP_957198.1

Gene Ontology
Bibliography

Related articles in PubMed

Kindlin 3 (FERMT3) is associated with unstable atherosclerotic plaques, anti-inflammatory type II macrophages and upregulation of beta-2 integrins in all major arterial beds.
Oksala N, P?rssinen J, Sepp?l? I, Klopp N, Illig T, Laaksonen R, Levula M, Raitoharju E, Kholova I, Sioris T, K?h?nen M, Lehtim?ki T, Hyt?nen VP
Atherosclerosis242(1)145-54(2015 Sep)

Talins and kindlins: partners in integrin-mediated adhesion.
Calderwood DA, Campbell ID, Critchley DR
Nature reviews. Molecular cell biology14(8)503-17(2013 Aug)

Platelet proteome analysis reveals integrin-dependent aggregation defects in patients with myelodysplastic syndromes.
Fr?bel J, Cadeddu RP, Hartwig S, Bruns I, Wilk CM, K?ndgen A, Fischer JC, Schroeder T, Steidl UG, Germing U, Lehr S, Haas R, Czibere A
Molecular & cellular proteomics : MCP12(5)1272-80(2013 May)

Discovery of serum biomarkers implicated in the onset and progression of serous ovarian cancer in a rat model using iTRAQ technique.
Huang Y, Zhang X, Jiang W, Wang Y, Jin H, Liu X, Xu C
European journal of obstetrics, gynecology, and reproductive biology165(1)96-103(2012 Nov)

[Expression of Kindlins and angiopoietins in acute myeloid leukemia].
Wu WB, Zhang Q, Li Y, Shan SL, Li XY, Tian Z, Tang KJ, Wang M, Rao Q, Mi YC
Zhongguo shi yan xue ye xue za zhi20(1)7-11(2012 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Fermt3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fermt3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01883	NM_001127543.1 Latest version!	Rattus norvegicus fermitin family member 3 (Fermt3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$391.30 $559.00
ORa23781	XM_006230811.3 Latest version!	Rattus norvegicus fermitin family member 3 (Fermt3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fermt3 ( NM_001127543.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001121015.1 Rattus norvegicus fermitin family member 3 (Fermt3), mRNA.

Price & Availability↑

CloneID	ORa01883
Clone ID Related Accession (Same CDS sequence)	NM_001127543.1
Accession Version	NM_001127543.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1998bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-09
Organism	Rattus norvegicus(Norway rat)
Product	fermitin family homolog 3
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC166607.1. On or before May 23, 2008 this sequence version replaced XM_219540.4, XM_001076361.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC166607.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCGGGGA TGAAGACAGC CTCCGGAGAC TATATCGACT CTTCCTGGGA GCTGAGGGTG 
TTTGTGGGCG AGGAAGACCC TGAGGCTCAG TCTGTCACAC TCCGAGTCAC AGGGGAGTCC 
CACATTGGTG GGGTGCTTCT GAAGATCGTG GAGGAGATCA ATCGCAAGCA GGACTGGTCT 
GACCATGCCA TTTGGTGGGA GCAGAAGAAA CAGTGGCTGC TACAGACACA CTGGACTCTG 
GACAAGTATG GGATTCTGGC AGATGCCCGC CTCTTCTTTG GGCCACAGCA CCGACCTGTG 
ATCCTGCGAC TGCCCAATAG GCGGGTGCTG CGCCTCCGTG CCAGCTTCTC CAAGCCCCTC 
TTCCAGACTG TGGCTGCCAT CTGCCGCCTC CTCAGTATCA GGCACCCAGA GGAGCTCTCT 
CTGCTGCGCG CTCCAGAAAA GAAGGAGAAG AAGAAGAAAG AGAAGGAGCC TGAGGAAGAG 
GTGCATGACC TGACAAGGGT TGTTCTAGCC GGCGGTGTGG CCCCCACCTT ATTCCGAGGC 
ATGCCAGCAC ACTTCTCGGA CAGCGCCCAG ACCGAGGCCT GTTACCACAT GCTGAGCCGG 
CCACAGCCAG CACCTGACCC TCTCCTGCTC CAGCGCCTGC CGAGGCCCAG CTCCCTGCTT 
GACAAGACCC AACTCCACAG CAGGTGGCTG GATTCATCTC GGTGCCTCAT GCAGCAAGGT 
ATCAAGGCTG GGGACGTGCT TTGGCTGCGA TTTAAGTACT ACAGCTTTTT CGACCTGGAC 
CCCAAGACAG ACCCGGTACG GCTGACCCAG CTGTATGAGC AGGCACGCTG GGATTTACTG 
ACAGAGGAAA TCGACTGTAC TGAGGAGGAG ATGATGGTGT TTGCTGCCCT ACAGTACCAT 
ATCAACAAAG TGACTCTGAG TGGGGATGTG GGTGAGCTGG CCTCTGGGGA CCCGGGGCTG 
GATGACCTGG ATGCAGCCTT GAACAACCTG GAGGTGAAGC TGAAGGGGTC AGCACCCTCA 
GACATGCTGG ATAGCCTCAC CACCATCCCA GAACTCAAGG ACCATCTCCG AATCTTCCGG 
CCCCGGAAGC TGACCTTGAA GGGCTACCGC CAGCACTGGG TGATATTCAA GGACACCACA 
CTGTCCTACT ATAAGAGCCA AGATGAAGCA CCGGGGGACC CTATCCAGCA GCTCAACCTC 
AAGGGCTGTG AAGTGGTCCC TGATGTCAAT GTCTCTGGCC AGAAGTTCTG CATCAAACTC 
CTGGTACCCT CACCAGAGGG CATGAGTGAG ATCTACTTGA GATGCCAGGA TGAACAGCAG 
TATGCACAGT GGATGGCTGC CTGCCGGCTT GCCTCCAAGG GCCGCACCAT GGCGGACAGC 
AGCTATGCCA GTGAGGTGCA GGCCATTCTG GCCTTCCTCA GCCTGCAGCG GGCAGGCGGT 
ACCAACGGAG GCTCAGGGAA CAAACCCCAG GGTCTTGAAG CCTCTGCTGA GGGCCTTAAC 
CCCTACGGCC TTGTGGCTCC CCGATTCCAG CGAAAGTTCA AGGCCAAGCA GCTCACCCCC 
CGGATCCTGG AAGCTCACCA GAATGTGGCC CAACTCTCGC TGACCGAGGC CCAGCTGCGC 
TTCATCCAGG CCTGGCAATC CCTGCCTGAT TTTGGCATCT CCTATGTGAT AGTCAGGTTC 
AAGGGCAGCA GGAAGGATGA GATTCTGGGC ATCGCCAACA ACCGACTGAT CCGAATTGAT 
CTGGCCGTGG GTGACGTGGT CAAGACCTGG CGCTTCAGCA ACATGCGGCA ATGGAACGTC 
AACTGGGACA TACGGCAGGT GGCCATTGAG TTCGATGAAC ATATCAATGT GGCCTTCAGC 
TGTGTGTCTG CTAGCTGCCG CATCGTGCAC GAGTACATCG GGGGCTACAT TTTCCTGTCC 
ACTCGAGAGC GGGCCCGAGG GGAGGAGCTG GACGAGGATC TGTTCCTACA GCTTACTGGA 
GGGCATGAGG CCTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001121015.1
CDS	110..2107
Translation	MAGMKTASGDYIDSSWELRVFVGEEDPEAQSVTLRVTGESHIGGVLLKIVEEINRKQDWSDHAIWWEQKKQWLLQTHWTLDKYGILADARLFFGPQHRPVILRLPNRRVLRLRASFSKPLFQTVAAICRLLSIRHPEELSLLRAPEKKEKKKKEKEPEEEVHDLTRVVLAGGVAPTLFRGMPAHFSDSAQTEACYHMLSRPQPAPDPLLLQRLPRPSSLLDKTQLHSRWLDSSRCLMQQGIKAGDVLWLRFKYYSFFDLDPKTDPVRLTQLYEQARWDLLTEEIDCTEEEMMVFAALQYHINKVTLSGDVGELASGDPGLDDLDAALNNLEVKLKGSAPSDMLDSLTTIPELKDHLRIFRPRKLTLKGYRQHWVIFKDTTLSYYKSQDEAPGDPIQQLNLKGCEVVPDVNVSGQKFCIKLLVPSPEGMSEIYLRCQDEQQYAQWMAACRLASKGRTMADSSYASEVQAILAFLSLQRAGGTNGGSGNKPQGLEASAEGLNPYGLVAPRFQRKFKAKQLTPRILEAHQNVAQLSLTEAQLRFIQAWQSLPDFGISYVIVRFKGSRKDEILGIANNRLIRIDLAVGDVVKTWRFSNMRQWNVNWDIRQVAIEFDEHINVAFSCVSASCRIVHEYIGGYIFLSTRERARGEELDEDLFLQLTGGHEAF

Target ORF information:

RefSeq Version	NM_001127543.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus fermitin family member 3 (Fermt3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001127543.1

ORF Insert Sequence:

ATGGCGGGGA TGAAGACAGC CTCCGGAGAC TATATCGACT CTTCCTGGGA GCTGAGGGTG 
TTTGTGGGCG AGGAAGACCC TGAGGCTCAG TCTGTCACAC TCCGAGTCAC AGGGGAGTCC 
CACATTGGTG GGGTGCTTCT GAAGATCGTG GAGGAGATCA ATCGCAAGCA GGACTGGTCT 
GACCATGCCA TTTGGTGGGA GCAGAAGAAA CAGTGGCTGC TACAGACACA CTGGACTCTG 
GACAAGTATG GGATTCTGGC AGATGCCCGC CTCTTCTTTG GGCCACAGCA CCGACCTGTG 
ATCCTGCGAC TGCCCAATAG GCGGGTGCTG CGCCTCCGTG CCAGCTTCTC CAAGCCCCTC 
TTCCAGACTG TGGCTGCCAT CTGCCGCCTC CTCAGTATCA GGCACCCAGA GGAGCTCTCT 
CTGCTGCGCG CTCCAGAAAA GAAGGAGAAG AAGAAGAAAG AGAAGGAGCC TGAGGAAGAG 
GTGCATGACC TGACAAGGGT TGTTCTAGCC GGCGGTGTGG CCCCCACCTT ATTCCGAGGC 
ATGCCAGCAC ACTTCTCGGA CAGCGCCCAG ACCGAGGCCT GTTACCACAT GCTGAGCCGG 
CCACAGCCAG CACCTGACCC TCTCCTGCTC CAGCGCCTGC CGAGGCCCAG CTCCCTGCTT 
GACAAGACCC AACTCCACAG CAGGTGGCTG GATTCATCTC GGTGCCTCAT GCAGCAAGGT 
ATCAAGGCTG GGGACGTGCT TTGGCTGCGA TTTAAGTACT ACAGCTTTTT CGACCTGGAC 
CCCAAGACAG ACCCGGTACG GCTGACCCAG CTGTATGAGC AGGCACGCTG GGATTTACTG 
ACAGAGGAAA TCGACTGTAC TGAGGAGGAG ATGATGGTGT TTGCTGCCCT ACAGTACCAT 
ATCAACAAAG TGACTCTGAG TGGGGATGTG GGTGAGCTGG CCTCTGGGGA CCCGGGGCTG 
GATGACCTGG ATGCAGCCTT GAACAACCTG GAGGTGAAGC TGAAGGGGTC AGCACCCTCA 
GACATGCTGG ATAGCCTCAC CACCATCCCA GAACTCAAGG ACCATCTCCG AATCTTCCGG 
CCCCGGAAGC TGACCTTGAA GGGCTACCGC CAGCACTGGG TGATATTCAA GGACACCACA 
CTGTCCTACT ATAAGAGCCA AGATGAAGCA CCGGGGGACC CTATCCAGCA GCTCAACCTC 
AAGGGCTGTG AAGTGGTCCC TGATGTCAAT GTCTCTGGCC AGAAGTTCTG CATCAAACTC 
CTGGTACCCT CACCAGAGGG CATGAGTGAG ATCTACTTGA GATGCCAGGA TGAACAGCAG 
TATGCACAGT GGATGGCTGC CTGCCGGCTT GCCTCCAAGG GCCGCACCAT GGCGGACAGC 
AGCTATGCCA GTGAGGTGCA GGCCATTCTG GCCTTCCTCA GCCTGCAGCG GGCAGGCGGT 
ACCAACGGAG GCTCAGGGAA CAAACCCCAG GGTCTTGAAG CCTCTGCTGA GGGCCTTAAC 
CCCTACGGCC TTGTGGCTCC CCGATTCCAG CGAAAGTTCA AGGCCAAGCA GCTCACCCCC 
CGGATCCTGG AAGCTCACCA GAATGTGGCC CAACTCTCGC TGACCGAGGC CCAGCTGCGC 
TTCATCCAGG CCTGGCAATC CCTGCCTGAT TTTGGCATCT CCTATGTGAT AGTCAGGTTC 
AAGGGCAGCA GGAAGGATGA GATTCTGGGC ATCGCCAACA ACCGACTGAT CCGAATTGAT 
CTGGCCGTGG GTGACGTGGT CAAGACCTGG CGCTTCAGCA ACATGCGGCA ATGGAACGTC 
AACTGGGACA TACGGCAGGT GGCCATTGAG TTCGATGAAC ATATCAATGT GGCCTTCAGC 
TGTGTGTCTG CTAGCTGCCG CATCGTGCAC GAGTACATCG GGGGCTACAT TTTCCTGTCC 
ACTCGAGAGC GGGCCCGAGG GGAGGAGCTG GACGAGGATC TGTTCCTACA GCTTACTGGA 
GGGCATGAGG CCTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fermt3 ( XM_006230811.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006230873.1 Rattus norvegicus fermitin family member 3 (Fermt3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa23781
Clone ID Related Accession (Same CDS sequence)	XM_006230811.3
Accession Version	XM_006230811.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1998bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	fermitin family homolog 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006230811.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGGGA TGAAGACAGC CTCCGGAGAC TATATCGACT CTTCCTGGGA GCTGAGGGTG 
TTTGTGGGCG AGGAAGACCC TGAGGCTCAG TCTGTCACAC TCCGAGTCAC AGGGGAGTCC 
CACATTGGTG GGGTGCTTCT GAAGATCGTG GAGGAGATCA ATCGCAAGCA GGACTGGTCT 
GACCATGCCA TTTGGTGGGA GCAGAAGAAA CAGTGGCTGC TACAGACACA CTGGACTCTG 
GACAAGTACG GGATTCTGGC AGATGCCCGC CTCTTCTTTG GGCCACAGCA CCGACCTGTG 
ATCCTGCGAC TGCCCAATAG GCGGGTGCTG CGCCTCCGTG CCAGCTTCTC CAAGCCCCTC 
TTCCAGACTG TGGCTGCCAT CTGCCGCCTC CTCAGTATCA GGCACCCAGA GGAGCTCTCT 
CTGCTGCGCG CTCCAGAAAA GAAGGAGAAG AAGAAGAAAG AGAAGGAGCC TGAGGAAGAG 
GTGCATGACC TGACAAGGGT TGTTCTAGCC GGCGGTGTGG CCCCCACCTT ATTCCGAGGC 
ATGCCAGCAC ACTTCTCGGA CAGCGCCCAG ACCGAGGCCT GTTACCACAT GCTGAGCCGG 
CCACAGCCAG CACCTGACCC TCTCCTGCTC CAGCGCCTGC CGAGGCCCAG CTCCCTGCTT 
GACAAGACCC AACTCCACAG CAGGTGGCTG GATTCATCTC GGTGCCTCAT GCAGCAAGGT 
ATCAAGGCTG GGGACGTGCT TTGGCTGCGA TTTAAGTACT ACAGCTTTTT CGACCTGGAC 
CCCAAGACAG ACCCGGTACG GCTGACCCAG CTGTATGAGC AGGCACGCTG GGATTTACTG 
ACAGAGGAAA TCGACTGTAC TGAGGAGGAG ATGATGGTGT TTGCTGCCCT ACAGTACCAT 
ATCAACAAAG TGACTCTGAG TGGGGATGTG GGTGAGCTGG CCTCTGGGGA CCCGGGGCTG 
GATGACCTGG ATGCAGCCTT GAACAACCTG GAGGTGAAGC TGAAGGGGTC AGCACCCTCA 
GACATGCTGG ATAGCCTCAC CACCATCCCA GAACTCAAGG ACCATCTCCG AATCTTCCGG 
CCCCGGAAGC TGACCTTGAA GGGCTACCGC CAGCACTGGG TGATATTCAA GGACACCACA 
CTGTCCTACT ATAAGAGCCA AGATGAAGCA CCGGGGGACC CTATCCAGCA GCTCAACCTC 
AAGGGCTGTG AAGTGGTCCC TGATGTCAAT GTCTCTGGCC AGAAGTTCTG CATCAAACTC 
CTGGTACCCT CACCAGAGGG CATGAGTGAG ATCTACTTGA GATGCCAGGA TGAACAGCAG 
TATGCACAGT GGATGGCTGC CTGCCGGCTT GCCTCCAAGG GCCGCACCAT GGCGGACAGC 
AGCTATGCCA GTGAGGTGCA GGCCATTCTG GCCTTCCTCA GCCTGCAGCG GGCAGGCGGT 
ACCAACGGAG GCTCAGGGAA CAAACCCCAG GGTCTTGAAG CCTCTGCTGA GGGCCTTAAC 
CCCTACGGCC TTGTGGCTCC CCGATTCCAG CGAAAGTTCA AGGCCAAGCA GCTCACCCCC 
CGGATCCTGG AAGCTCACCA GAATGTGGCC CAACTCTCGC TGACCGAGGC CCAGCTGCGC 
TTCATCCAGG CCTGGCAATC CCTGCCTGAT TTTGGCATCT CCTATGTGAT AGTCAGGTTC 
AAGGGCAGCA GGAAGGATGA GATTCTGGGC ATCGCCAACA ACCGACTGAT CCGAATTGAT 
CTGGCCGTGG GTGACGTGGT CAAGACCTGG CGCTTCAGCA ACATGCGGCA ATGGAACGTC 
AACTGGGACA TACGGCAGGT GGCCATTGAG TTCGATGAAC ATATCAATGT GGCCTTCAGC 
TGTGTGTCTG CTAGCTGCCG CATCGTGCAC GAGTACATCG GGGGCTACAT TTTCCTGTCC 
ACTCGAGAGC GGGCCCGAGG GGAGGAGCTG GACGAGGATC TGTTCCTACA GCTTACTGGA 
GGGCATGAGG CCTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006230873.1
CDS	597..2594
Translation	MAGMKTASGDYIDSSWELRVFVGEEDPEAQSVTLRVTGESHIGGVLLKIVEEINRKQDWSDHAIWWEQKKQWLLQTHWTLDKYGILADARLFFGPQHRPVILRLPNRRVLRLRASFSKPLFQTVAAICRLLSIRHPEELSLLRAPEKKEKKKKEKEPEEEVHDLTRVVLAGGVAPTLFRGMPAHFSDSAQTEACYHMLSRPQPAPDPLLLQRLPRPSSLLDKTQLHSRWLDSSRCLMQQGIKAGDVLWLRFKYYSFFDLDPKTDPVRLTQLYEQARWDLLTEEIDCTEEEMMVFAALQYHINKVTLSGDVGELASGDPGLDDLDAALNNLEVKLKGSAPSDMLDSLTTIPELKDHLRIFRPRKLTLKGYRQHWVIFKDTTLSYYKSQDEAPGDPIQQLNLKGCEVVPDVNVSGQKFCIKLLVPSPEGMSEIYLRCQDEQQYAQWMAACRLASKGRTMADSSYASEVQAILAFLSLQRAGGTNGGSGNKPQGLEASAEGLNPYGLVAPRFQRKFKAKQLTPRILEAHQNVAQLSLTEAQLRFIQAWQSLPDFGISYVIVRFKGSRKDEILGIANNRLIRIDLAVGDVVKTWRFSNMRQWNVNWDIRQVAIEFDEHINVAFSCVSASCRIVHEYIGGYIFLSTRERARGEELDEDLFLQLTGGHEAF

Target ORF information:

RefSeq Version	XM_006230811.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus fermitin family member 3 (Fermt3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006230811.3

ORF Insert Sequence:

ATGGCGGGGA TGAAGACAGC CTCCGGAGAC TATATCGACT CTTCCTGGGA GCTGAGGGTG 
TTTGTGGGCG AGGAAGACCC TGAGGCTCAG TCTGTCACAC TCCGAGTCAC AGGGGAGTCC 
CACATTGGTG GGGTGCTTCT GAAGATCGTG GAGGAGATCA ATCGCAAGCA GGACTGGTCT 
GACCATGCCA TTTGGTGGGA GCAGAAGAAA CAGTGGCTGC TACAGACACA CTGGACTCTG 
GACAAGTACG GGATTCTGGC AGATGCCCGC CTCTTCTTTG GGCCACAGCA CCGACCTGTG 
ATCCTGCGAC TGCCCAATAG GCGGGTGCTG CGCCTCCGTG CCAGCTTCTC CAAGCCCCTC 
TTCCAGACTG TGGCTGCCAT CTGCCGCCTC CTCAGTATCA GGCACCCAGA GGAGCTCTCT 
CTGCTGCGCG CTCCAGAAAA GAAGGAGAAG AAGAAGAAAG AGAAGGAGCC TGAGGAAGAG 
GTGCATGACC TGACAAGGGT TGTTCTAGCC GGCGGTGTGG CCCCCACCTT ATTCCGAGGC 
ATGCCAGCAC ACTTCTCGGA CAGCGCCCAG ACCGAGGCCT GTTACCACAT GCTGAGCCGG 
CCACAGCCAG CACCTGACCC TCTCCTGCTC CAGCGCCTGC CGAGGCCCAG CTCCCTGCTT 
GACAAGACCC AACTCCACAG CAGGTGGCTG GATTCATCTC GGTGCCTCAT GCAGCAAGGT 
ATCAAGGCTG GGGACGTGCT TTGGCTGCGA TTTAAGTACT ACAGCTTTTT CGACCTGGAC 
CCCAAGACAG ACCCGGTACG GCTGACCCAG CTGTATGAGC AGGCACGCTG GGATTTACTG 
ACAGAGGAAA TCGACTGTAC TGAGGAGGAG ATGATGGTGT TTGCTGCCCT ACAGTACCAT 
ATCAACAAAG TGACTCTGAG TGGGGATGTG GGTGAGCTGG CCTCTGGGGA CCCGGGGCTG 
GATGACCTGG ATGCAGCCTT GAACAACCTG GAGGTGAAGC TGAAGGGGTC AGCACCCTCA 
GACATGCTGG ATAGCCTCAC CACCATCCCA GAACTCAAGG ACCATCTCCG AATCTTCCGG 
CCCCGGAAGC TGACCTTGAA GGGCTACCGC CAGCACTGGG TGATATTCAA GGACACCACA 
CTGTCCTACT ATAAGAGCCA AGATGAAGCA CCGGGGGACC CTATCCAGCA GCTCAACCTC 
AAGGGCTGTG AAGTGGTCCC TGATGTCAAT GTCTCTGGCC AGAAGTTCTG CATCAAACTC 
CTGGTACCCT CACCAGAGGG CATGAGTGAG ATCTACTTGA GATGCCAGGA TGAACAGCAG 
TATGCACAGT GGATGGCTGC CTGCCGGCTT GCCTCCAAGG GCCGCACCAT GGCGGACAGC 
AGCTATGCCA GTGAGGTGCA GGCCATTCTG GCCTTCCTCA GCCTGCAGCG GGCAGGCGGT 
ACCAACGGAG GCTCAGGGAA CAAACCCCAG GGTCTTGAAG CCTCTGCTGA GGGCCTTAAC 
CCCTACGGCC TTGTGGCTCC CCGATTCCAG CGAAAGTTCA AGGCCAAGCA GCTCACCCCC 
CGGATCCTGG AAGCTCACCA GAATGTGGCC CAACTCTCGC TGACCGAGGC CCAGCTGCGC 
TTCATCCAGG CCTGGCAATC CCTGCCTGAT TTTGGCATCT CCTATGTGAT AGTCAGGTTC 
AAGGGCAGCA GGAAGGATGA GATTCTGGGC ATCGCCAACA ACCGACTGAT CCGAATTGAT 
CTGGCCGTGG GTGACGTGGT CAAGACCTGG CGCTTCAGCA ACATGCGGCA ATGGAACGTC 
AACTGGGACA TACGGCAGGT GGCCATTGAG TTCGATGAAC ATATCAATGT GGCCTTCAGC 
TGTGTGTCTG CTAGCTGCCG CATCGTGCAC GAGTACATCG GGGGCTACAT TTTCCTGTCC 
ACTCGAGAGC GGGCCCGAGG GGAGGAGCTG GACGAGGATC TGTTCCTACA GCTTACTGGA 
GGGCATGAGG CCTTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Kindlin 3 (FERMT3) is associated with unstable atherosclerotic plaques, anti-inflammatory type II macrophages and upregulation of beta-2 integrins in all major arterial beds.
Atherosclerosis242(1)145-54(2015 Sep)
Oksala N,P?rssinen J,Sepp?l? I,Klopp N,Illig T,Laaksonen R,Levula M,Raitoharju E,Kholova I,Sioris T,K?h?nen M,Lehtim?ki T,Hyt?nen VP

Talins and kindlins: partners in integrin-mediated adhesion.
Nature reviews. Molecular cell biology14(8)503-17(2013 Aug)
Calderwood DA,Campbell ID,Critchley DR

Platelet proteome analysis reveals integrin-dependent aggregation defects in patients with myelodysplastic syndromes.
Molecular & cellular proteomics : MCP12(5)1272-80(2013 May)
Fr?bel J,Cadeddu RP,Hartwig S,Bruns I,Wilk CM,K?ndgen A,Fischer JC,Schroeder T,Steidl UG,Germing U,Lehr S,Haas R,Czibere A

Discovery of serum biomarkers implicated in the onset and progression of serous ovarian cancer in a rat model using iTRAQ technique.
European journal of obstetrics, gynecology, and reproductive biology165(1)96-103(2012 Nov)
Huang Y,Zhang X,Jiang W,Wang Y,Jin H,Liu X,Xu C

[Expression of Kindlins and angiopoietins in acute myeloid leukemia].
Zhongguo shi yan xue ye xue za zhi20(1)7-11(2012 Feb)
Wu WB,Zhang Q,Li Y,Shan SL,Li XY,Tian Z,Tang KJ,Wang M,Rao Q,Mi YC

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Fermt3 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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