Klk12 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Klk12
Entrez Gene ID	308564
Full Name	kallikrein related-peptidase 12
Synonyms	Klnk
General protein information	Preferred Names kallikrein related-peptidase 12 Names kallikrein-12 kallikrein 12 kallikrein k
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q22

mRNA and Protein(s)

mRNA	Protein	Name
NM_001107508.1	NP_001100978.1	kallikrein-12
XM_008759351.1	XP_008757573.1	kallikrein-12 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	KLK12	NP_665901.1
Canis lupus familiaris (dog)	KLK12	XP_854572.1
Pan troglodytes (chimpanzee)	KLK12	XP_001174137.1
Bos taurus (cattle)	KLK12	NP_001180119.1
Mus musculus (house mouse)	Klk12	NP_081373.1
Rattus norvegicus (Norway rat)	Klk12	NP_001100978.1

Gene Ontology
Bibliography

Related articles in PubMed

Kallikrein-related peptidase 12 hydrolyzes matricellular proteins of the CCN family and modifies interactions of CCN1 and CCN5 with growth factors.
Guillon-Munos A, Oikonomopoulou K, Michel N, Smith CR, Petit-Courty A, Canepa S, Reverdiau P, Heuz?-Vourc'h N, Diamandis EP, Courty Y
The Journal of biological chemistry286(29)25505-18(2011 Jul)

Klk1 as one of the genes contributing to hypertension in Dahl salt-sensitive rat.
Iwai N, Yasui N, Naraba H, Tago N, Yamawaki H, Sumiya H
Hypertension (Dallas, Tex. : 1979)45(5)947-53(2005 May)

Splice-site genetic polymorphism of the human kallikrein 12 (KLK12) gene correlates with no substantial expression of KLK12 protein having serine protease activity.
Shinmura K, Tao H, Yamada H, Kataoka H, Sanjar R, Wang J, Yoshimura K, Sugimura H
Human mutation24(3)273-4(2004 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Klk12 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Klk12 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa11277	NM_001107508.1 Latest version!	Rattus norvegicus kallikrein related-peptidase 12 (Klk12), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
ORa22716	XM_008759351.1 Latest version!	Rattus norvegicus kallikrein related-peptidase 12 (Klk12), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Klk12 ( NM_001107508.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001100978.1 Rattus norvegicus kallikrein related-peptidase 12 (Klk12), mRNA.

Price & Availability↑

CloneID	ORa11277
Clone ID Related Accession (Same CDS sequence)	NM_001107508.1
Accession Version	NM_001107508.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 543bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	kallikrein-12
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473979.2. On or before Oct 4, 2007 this sequence version replaced XM_218644.4, XM_001080413.1. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA2689600, SAMN02642690 [ECO:0000350] ##Evidence-Data-END##

ATGGTGCGCC TTGGGGAACA CAGTCTCTCC AAGCTGGATT TGACGGAACA GTTGAGACTC 
ACCACCTTCT CCATAACACA CCCCAGCTAC CATGGTGCCT ATCAGAACCA TGAGCATGAT 
CTTCGACTCC TACGGCTGAA CAGACCCATC AGCTTGACCT ATGCTGTCCG GCCCGTGGCC 
CTGCCCAGTT CCTGTGCACC CACTGGGGCC AAGTGTCATA TATCAGGATG GGGTACTACA 
AACAAGCCGT GGGACCCATT CCCAGATCGG CTCCAGTGCC TCGACCTCTC CATTGTCTCT 
AACGAGACGT GCCGGGCCGT ATTTCCTGGA AGAGTGACAG AGAACATGTT GTGTGCAGGT 
GGAGAAGCCG GAAAGGATGC CTGTCAGGGT GACTCTGGAG GCCCCCTGGT GTGTGGAGGG 
GTTCTTCAAG GTCTGGTTTC CTGGGGATCT GTTGGGCCTT GTGGTCAAAA AGGCATCCCA 
GGGGTCTACA CCAAGGTCTG CAAATACACG GACTGGATCA GAGTAGTCAT CAGGAACAAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001100978.1
CDS	164..706
Translation	MVRLGEHSLSKLDLTEQLRLTTFSITHPSYHGAYQNHEHDLRLLRLNRPISLTYAVRPVALPSSCAPTGAKCHISGWGTTNKPWDPFPDRLQCLDLSIVSNETCRAVFPGRVTENMLCAGGEAGKDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQKGIPGVYTKVCKYTDWIRVVIRNN

Target ORF information:

RefSeq Version	NM_001107508.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus kallikrein related-peptidase 12 (Klk12), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001107508.1

ORF Insert Sequence:

ATGGTGCGCC TTGGGGAACA CAGTCTCTCC AAGCTGGATT TGACGGAACA GTTGAGACTC 
ACCACCTTCT CCATAACACA CCCCAGCTAC CATGGTGCCT ATCAGAACCA TGAGCATGAT 
CTTCGACTCC TACGGCTGAA CAGACCCATC AGCTTGACCT ATGCTGTCCG GCCCGTGGCC 
CTGCCCAGTT CCTGTGCACC CACTGGGGCC AAGTGTCATA TATCAGGATG GGGTACTACA 
AACAAGCCGT GGGACCCATT CCCAGATCGG CTCCAGTGCC TCGACCTCTC CATTGTCTCT 
AACGAGACGT GCCGGGCCGT ATTTCCTGGA AGAGTGACAG AGAACATGTT GTGTGCAGGT 
GGAGAAGCCG GAAAGGATGC CTGTCAGGGT GACTCTGGAG GCCCCCTGGT GTGTGGAGGG 
GTTCTTCAAG GTCTGGTTTC CTGGGGATCT GTTGGGCCTT GTGGTCAAAA AGGCATCCCA 
GGGGTCTACA CCAAGGTCTG CAAATACACG GACTGGATCA GAGTAGTCAT CAGGAACAAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Klk12 ( XM_008759351.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008757573.1 Rattus norvegicus kallikrein related-peptidase 12 (Klk12), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa22716
Clone ID Related Accession (Same CDS sequence)	XM_008759351.1
Accession Version	XM_008759351.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 744bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	kallikrein-12 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGCTCA ACATTCTCTT GCTCCTGTGT GTTGTAGGCC TCAGTCAGGC AGACAGGGAG 
AAGATCTATA ATGGCGTTGA GTGTGTGAAG AACTCACAGC CTTGGCAGGT GGGGCTGTTC 
CATGGCAAAT ACCTGCGCTG TGGTGGTGTC CTCGTGGACC GCAAGTGGGT CCTTACGGCT 
GCTCACTGCA GTGGCAAGTA CATGGTGCGC CTTGGGGAAC ACAGTCTCTC CAAGCTGGAT 
TTGACGGAAC AGTTGAGACT CACCACCTTC TCCATAACAC ACCCCAGCTA CCATGGTGCC 
TATCAGAACC ATGAGCATGA TCTTCGACTC CTACGGCTGA ACAGACCCAT CAGCTTGACC 
TATGCTGTCC GGCCCGTGGC CCTGCCCAGT TCCTGTGCAC CCACTGGGGC CAAGTGTCAT 
ATATCAGGAT GGGGTACTAC AAACAAGCCG TGGGACCCAT TCCCAGATCG GCTCCAGTGC 
CTCGACCTCT CCATTGTCTC TAACGAGACG TGCCGGGCCG TATTTCCTGG AAGAGTGACA 
GAGAACATGT TGTGTGCAGG TGGAGAAGCC GGAAAGGATG CCTGTCAGGG TGACTCTGGA 
GGCCCCCTGG TGTGTGGAGG GGTTCTTCAA GGTCTGGTTT CCTGGGGATC TGTTGGGCCT 
TGTGGTCAAA AAGGCATCCC AGGGGTCTAC ACCAAGGTCT GCAAATACAC GGACTGGATC 
AGAGTAGTCA TCAGGAACAA CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008757573.1
CDS	43..786
Translation	MKLNILLLLCVVGLSQADREKIYNGVECVKNSQPWQVGLFHGKYLRCGGVLVDRKWVLTAAHCSGKYMVRLGEHSLSKLDLTEQLRLTTFSITHPSYHGAYQNHEHDLRLLRLNRPISLTYAVRPVALPSSCAPTGAKCHISGWGTTNKPWDPFPDRLQCLDLSIVSNETCRAVFPGRVTENMLCAGGEAGKDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQKGIPGVYTKVCKYTDWIRVVIRNN

Target ORF information:

RefSeq Version	XM_008759351.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus kallikrein related-peptidase 12 (Klk12), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008759351.1

ORF Insert Sequence:

ATGAAGCTCA ACATTCTCTT GCTCCTGTGT GTTGTAGGCC TCAGTCAGGC AGACAGGGAG 
AAGATCTATA ATGGCGTTGA GTGTGTGAAG AACTCACAGC CTTGGCAGGT GGGGCTGTTC 
CATGGCAAAT ACCTGCGCTG TGGTGGTGTC CTCGTGGACC GCAAGTGGGT CCTTACGGCT 
GCTCACTGCA GTGGCAAGTA CATGGTGCGC CTTGGGGAAC ACAGTCTCTC CAAGCTGGAT 
TTGACGGAAC AGTTGAGACT CACCACCTTC TCCATAACAC ACCCCAGCTA CCATGGTGCC 
TATCAGAACC ATGAGCATGA TCTTCGACTC CTACGGCTGA ACAGACCCAT CAGCTTGACC 
TATGCTGTCC GGCCCGTGGC CCTGCCCAGT TCCTGTGCAC CCACTGGGGC CAAGTGTCAT 
ATATCAGGAT GGGGTACTAC AAACAAGCCG TGGGACCCAT TCCCAGATCG GCTCCAGTGC 
CTCGACCTCT CCATTGTCTC TAACGAGACG TGCCGGGCCG TATTTCCTGG AAGAGTGACA 
GAGAACATGT TGTGTGCAGG TGGAGAAGCC GGAAAGGATG CCTGTCAGGG TGACTCTGGA 
GGCCCCCTGG TGTGTGGAGG GGTTCTTCAA GGTCTGGTTT CCTGGGGATC TGTTGGGCCT 
TGTGGTCAAA AAGGCATCCC AGGGGTCTAC ACCAAGGTCT GCAAATACAC GGACTGGATC 
AGAGTAGTCA TCAGGAACAA CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Kallikrein-related peptidase 12 hydrolyzes matricellular proteins of the CCN family and modifies interactions of CCN1 and CCN5 with growth factors.
The Journal of biological chemistry286(29)25505-18(2011 Jul)
Guillon-Munos A,Oikonomopoulou K,Michel N,Smith CR,Petit-Courty A,Canepa S,Reverdiau P,Heuz?-Vourc'h N,Diamandis EP,Courty Y

Klk1 as one of the genes contributing to hypertension in Dahl salt-sensitive rat.
Hypertension (Dallas, Tex. : 1979)45(5)947-53(2005 May)
Iwai N,Yasui N,Naraba H,Tago N,Yamawaki H,Sumiya H

Splice-site genetic polymorphism of the human kallikrein 12 (KLK12) gene correlates with no substantial expression of KLK12 protein having serine protease activity.
Human mutation24(3)273-4(2004 Sep)
Shinmura K,Tao H,Yamada H,Kataoka H,Sanjar R,Wang J,Yoshimura K,Sugimura H

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Klk12 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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