gRNAs
The following Wdr62 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Wdr62 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa07222 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001191623.2 | |
| Accession Version | NM_001191623.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 4656bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-10-01 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | WD repeat-containing protein 62 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AAHX01004537.1, AAHX01004536.1 and AAHX01004535.1. On Apr 23, 2011 this sequence version replaced NM_001191623.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA2689599, SAMEA2689602 [ECO:0000350] ##Evidence-Data-END## | |
1 | ATGATGGCTG CCTTAGCGGC CGGAGGTTAC GCGCGGAGTG ACACGATAGA AAAGCTGTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001178552.2 |
| CDS | 1..4656 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001191623.2 |
1 | ATGATGGCTG CCTTAGCGGC CGGAGGTTAC GCGCGGAGTG ACACGATAGA AAAGCTGTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Novel splice-site mutation in WDR62 revealed by whole-exome sequencing in a Sudanese family with primary microcephaly. |
Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication. |
A novel single base pair duplication in WDR62 causes primary microcephaly. |
Microcephaly disease gene Wdr62 regulates mitotic progression of embryonic neural stem cells and brain size. |
The utility of exome sequencing for genetic diagnosis in a familial microcephaly epilepsy syndrome. |
