Tomm40 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tomm40
Entrez Gene ID	308416
Full Name	translocase of outer mitochondrial membrane 40
Synonyms	OM38,TOM40
General protein information	Preferred Names translocase of outer mitochondrial membrane 40 Names mitochondrial import receptor subunit TOM40 homolog mitochondrial outer membrane protein of 38 kDa outer membrane protein 38 kDa translocase of outer membrane 40 kDa subunit homolog translocase of outer mitochondrial membrane 40 homolog
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q21
Summary	mitochondrial-specific protein integral to the outer membrane; may be a component of the preprotein import machinery [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_212520.1	NP_997685.1	mitochondrial import receptor subunit TOM40 homolog
XM_006228420.3	XP_006228482.1	mitochondrial import receptor subunit TOM40 homolog isoform X1

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	tomboy40	NP_610213.1
Saccharomyces cerevisiae (baker's yeast)	TOM40	NP_013930.1
	TOMM40	XP_001109661.1
Drosophila melanogaster (fruit fly)	Tom40	NP_001259313.1
Caenorhabditis elegans (roundworm)	tomm-40	NP_495912.1
Kluyveromyces lactis	KLLA0F06292g	XP_455365.1
Eremothecium gossypii	AGOS_AFL183C	NP_985367.1
Xenopus tropicalis (tropical clawed frog)	tomm40	NP_989125.1
Homo sapiens (human)	TOMM40	NP_006105.1
Bos taurus (cattle)	TOMM40	NP_001068906.1
Rattus norvegicus (Norway rat)	Tomm40	NP_997685.1
Danio rerio (zebrafish)	tomm40	NP_955908.1
Schizosaccharomyces pombe (fission yeast)	tom40	NP_595546.2
Arabidopsis thaliana (thale cress)	AT1G50400	NP_175457.1
Canis lupus familiaris (dog)	TOMM40	XP_852633.1
Magnaporthe oryzae (rice blast fungus)	MGG_08637	XP_003711067.1
Neurospora crassa	NCU01179	XP_961545.1
Mus musculus (house mouse)	Tomm40	NP_001103218.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007871	XP_317621.2

Gene Ontology
Bibliography

Related articles in PubMed

Biogenesis of mitochondrial outer membrane proteins, problems and diseases.
Ellenrieder L, M?rtensson CU, Becker T
Biological chemistry396(11)1199-213(2015 Nov)

Association of
Yamase Y, Horibe H, Ueyama C, Fujimaki T, Oguri M, Kato K, Arai M, Watanabe S, Yamada Y
Biomedical reports3(4)491-498(2015 Jul)

Cooperation of protein machineries in mitochondrial protein sorting.
Wenz LS, Opali?ski ?, Wiedemann N, Becker T
Biochimica et biophysica acta1853(5)1119-29(2015 May)

Unlocking the presequence import pathway.
Schulz C, Schendzielorz A, Rehling P
Trends in cell biology25(5)265-75(2015 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Import of Tom40 did not differ between young and aged animals, but its subsequent assembly into the final approximately 380 kDa complex was higher in mitochondria from aged compared with young animals. Chornic contractile activity altered Tom40 levels.
Title: Biogenesis of the mitochondrial Tom40 channel in skeletal muscle from aged animals and its adaptability to chronic contractile activity.

Tom40B is a functional component of mitochondrial outer membrane translocase
Title: Identification and characterization of a new tom40 isoform, a central component of mitochondrial outer membrane translocase.

C-terminal half of rTOM40 constitutes the preprotein recognition domain with an enriched beta-structure
Title: Membrane-embedded C-terminal segment of rat mitochondrial TOM40 constitutes protein-conducting pore with enriched beta-structure.

The following Tomm40 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tomm40 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa13051	NM_212520.1 Latest version!	Rattus norvegicus translocase of outer mitochondrial membrane 40 (Tomm40), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
ORa22408	XM_006228420.3 Latest version!	Rattus norvegicus translocase of outer mitochondrial membrane 40 (Tomm40), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tomm40 ( NM_212520.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_997685.1 Rattus norvegicus translocase of outer mitochondrial membrane 40 (Tomm40), mRNA.

Price & Availability↑

CloneID	ORa13051
Clone ID Related Accession (Same CDS sequence)	NM_212520.1
Accession Version	NM_212520.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1086bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Rattus norvegicus(Norway rat)
Product	mitochondrial import receptor subunit TOM40 homolog
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB162855.1. On Aug 30, 2004 this sequence version replaced XM_218426.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB162855.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906347 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END##

ATGGGGAACG TGTTGGCTGC TAGCTCTCCG CCCGCAGGGC CACCGCCGCC TCCTACGCCG 
TCCCTCGTGG GGCTCCCGCC GCCGCCTCCT TCGCCGCCAG GCTTCACGCT GCCGCCACTT 
GGAGGTGGCC TGGGCACTGG GTCAAACGCT GGTCGCGGTT CGGAACGGAC TCCCGGGGCC 
GCGGCGAGCG GCGCTGCGGC GTCCTCGAAC GATGGGAACT GCGGCTGCCT GCCCAACCCG 
GGGACGTTCG AGGAGTGCCA CCGGAAGTGC AAGGAGCTGT TTCCAGTTCA GATGGAAGGT 
GTCAAACTTA CAGTCAACAA AGGGTTAAGC AATCGTTTCC AGGTGACCCA TACAGTAGCC 
CTCGGCACAA TTGGGGAGTC CAACTACCAC TTCGGGGTTA CATACGTGGG GACAAAACAG 
CTGAGTCCCA CAGAGGCGTT CCCCGTGCTG GTGGGTGACA TGGACAATAG TGGCAGCCTC 
AATGCACAGG TCATCCACCA GCTGAGCCCA GGCCTCAGGT CCAAGATGGC CATCCAGACC 
CAGCAGTCCA AGTTCGTGAA CTGGCAGGTG GATGGCGAGT ACCGTGGCTC CGACTTCACG 
GCTGCTGTCA CCCTGGGCAA CCCAGATGTC TTGGTGGGTT CAGGAATCCT CGTGGCTCAC 
TACCTCCAGA GCATCACACC GTGTCTGGCC CTAGGTGGCG AGCTCGTCTA CCACCGGCGG 
CCTGGAGAAA AGGGCACTGT CATGTCTCTA GCTGGGAAAT ACACACTGAA CAACTGGTTG 
GCTACAGTAA CGCTGGGTCA GGCAGGCATG CATGCTACGT ATTACCACAA AGCCAGTGAC 
CAGCTGCAGG TGGGTGTGGA GTTTGAGGCC AGCACCAGGA TGCAGGACAC CAGTGCCTCC 
TTTGGGTATC AGCTGGACCT GCCCAAGGCC AACTTCCTCT TCAAAGGCTC TGTGAACAGT 
AACTGGATCG TGGGTGCCAC GCTGGAGAAG AAGCTTCCGC CCTTGCCCCT GACACTGTCG 
CTCTGCGCCT TCCTGAACCA CCGCAAGAAT AAGTTCCTGT GTGGCTTTGG CCTCACCATC 
GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_997685.1
CDS	1..1086
Translation	MGNVLAASSPPAGPPPPPTPSLVGLPPPPPSPPGFTLPPLGGGLGTGSNAGRGSERTPGAAASGAAASSNDGNCGCLPNPGTFEECHRKCKELFPVQMEGVKLTVNKGLSNRFQVTHTVALGTIGESNYHFGVTYVGTKQLSPTEAFPVLVGDMDNSGSLNAQVIHQLSPGLRSKMAIQTQQSKFVNWQVDGEYRGSDFTAAVTLGNPDVLVGSGILVAHYLQSITPCLALGGELVYHRRPGEKGTVMSLAGKYTLNNWLATVTLGQAGMHATYYHKASDQLQVGVEFEASTRMQDTSASFGYQLDLPKANFLFKGSVNSNWIVGATLEKKLPPLPLTLSLCAFLNHRKNKFLCGFGLTIG

Target ORF information:

RefSeq Version	NM_212520.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus translocase of outer mitochondrial membrane 40 (Tomm40), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_212520.1

ORF Insert Sequence:

ATGGGGAACG TGTTGGCTGC TAGCTCTCCG CCCGCAGGGC CACCGCCGCC TCCTACGCCG 
TCCCTCGTGG GGCTCCCGCC GCCGCCTCCT TCGCCGCCAG GCTTCACGCT GCCGCCACTT 
GGAGGTGGCC TGGGCACTGG GTCAAACGCT GGTCGCGGTT CGGAACGGAC TCCCGGGGCC 
GCGGCGAGCG GCGCTGCGGC GTCCTCGAAC GATGGGAACT GCGGCTGCCT GCCCAACCCG 
GGGACGTTCG AGGAGTGCCA CCGGAAGTGC AAGGAGCTGT TTCCAGTTCA GATGGAAGGT 
GTCAAACTTA CAGTCAACAA AGGGTTAAGC AATCGTTTCC AGGTGACCCA TACAGTAGCC 
CTCGGCACAA TTGGGGAGTC CAACTACCAC TTCGGGGTTA CATACGTGGG GACAAAACAG 
CTGAGTCCCA CAGAGGCGTT CCCCGTGCTG GTGGGTGACA TGGACAATAG TGGCAGCCTC 
AATGCACAGG TCATCCACCA GCTGAGCCCA GGCCTCAGGT CCAAGATGGC CATCCAGACC 
CAGCAGTCCA AGTTCGTGAA CTGGCAGGTG GATGGCGAGT ACCGTGGCTC CGACTTCACG 
GCTGCTGTCA CCCTGGGCAA CCCAGATGTC TTGGTGGGTT CAGGAATCCT CGTGGCTCAC 
TACCTCCAGA GCATCACACC GTGTCTGGCC CTAGGTGGCG AGCTCGTCTA CCACCGGCGG 
CCTGGAGAAA AGGGCACTGT CATGTCTCTA GCTGGGAAAT ACACACTGAA CAACTGGTTG 
GCTACAGTAA CGCTGGGTCA GGCAGGCATG CATGCTACGT ATTACCACAA AGCCAGTGAC 
CAGCTGCAGG TGGGTGTGGA GTTTGAGGCC AGCACCAGGA TGCAGGACAC CAGTGCCTCC 
TTTGGGTATC AGCTGGACCT GCCCAAGGCC AACTTCCTCT TCAAAGGCTC TGTGAACAGT 
AACTGGATCG TGGGTGCCAC GCTGGAGAAG AAGCTTCCGC CCTTGCCCCT GACACTGTCG 
CTCTGCGCCT TCCTGAACCA CCGCAAGAAT AAGTTCCTGT GTGGCTTTGG CCTCACCATC 
GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Tomm40 ( XM_006228420.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006228482.1 Rattus norvegicus translocase of outer mitochondrial membrane 40 (Tomm40), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa22408
Clone ID Related Accession (Same CDS sequence)	XM_006228420.3
Accession Version	XM_006228420.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1086bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	mitochondrial import receptor subunit TOM40 homolog isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006228420.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGAACG TGTTGGCTGC TAGCTCTCCG CCCGCAGGGC CACCGCCGCC TCCTACGCCG 
TCCCTCGTGG GGCTCCCGCC GCCGCCTCCT TCGCCGCCAG GCTTCACGCT GCCGCCACTT 
GGAGGTGGCC TGGGCACTGG GTCAAACGCT GGTCGCGGTT CGGAACGGAC TCCCGGGGCC 
GCGGCGAGCG GCGCTGCGGC GTCCTCGAAC GATGGGAACT GCGGCTGCCT GCCCAACCCG 
GGGACGTTCG AGGAGTGCCA CCGGAAGTGC AAGGAGCTGT TTCCAGTTCA GATGGAAGGT 
GTCAAACTTA CAGTCAACAA AGGGTTAAGC AATCGTTTCC AGGTGACCCA TACAGTAGCC 
CTCGGCACAA TTGGGGAGTC CAACTACCAC TTCGGGGTTA CATACGTGGG GACAAAACAG 
CTGAGTCCCA CAGAGGCGTT CCCCGTGCTG GTGGGTGACA TGGACAATAG TGGCAGCCTC 
AATGCACAGG TCATCCACCA GCTGAGCCCA GGCCTCAGGT CCAAGATGGC CATCCAGACC 
CAGCAGTCCA AGTTCGTGAA CTGGCAGGTG GATGGCGAGT ACCGTGGCTC CGACTTCACG 
GCTGCTGTCA CCCTGGGCAA CCCAGATGTC TTGGTGGGTT CAGGAATCCT CGTGGCTCAC 
TACCTCCAGA GCATCACACC GTGTCTGGCC CTAGGTGGCG AGCTCGTCTA CCACCGGCGG 
CCTGGAGAAG AGGGCACTGT CATGTCTCTA GCTGGGAAAT ACACACTGAA CAACTGGTTG 
GCTACAGTAA CGCTGGGTCA GGCAGGCATG CATGCGACGT ATTACCACAA AGCCAGTGAC 
CAGCTGCAGG TGGGTGTGGA GTTTGAGGCC AGCACCAGGA TGCAGGACAC CAGTGCCTCC 
TTTGGGTATC AGCTGGACCT GCCCAAGGCC AACTTCCTCT TCAAAGGCTC TGTGAACAGT 
AACTGGATCG TGGGTGCCAC GCTGGAGAAG AAGCTTCCGC CCTTGCCCCT GACACTGTCG 
CTCTGCGCCT TCCTGAACCA CCGCAAGAAT AAGTTCCTGT GTGGCTTTGG CCTCACCATC 
GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006228482.1
CDS	116..1201
Translation	MGNVLAASSPPAGPPPPPTPSLVGLPPPPPSPPGFTLPPLGGGLGTGSNAGRGSERTPGAAASGAAASSNDGNCGCLPNPGTFEECHRKCKELFPVQMEGVKLTVNKGLSNRFQVTHTVALGTIGESNYHFGVTYVGTKQLSPTEAFPVLVGDMDNSGSLNAQVIHQLSPGLRSKMAIQTQQSKFVNWQVDGEYRGSDFTAAVTLGNPDVLVGSGILVAHYLQSITPCLALGGELVYHRRPGEEGTVMSLAGKYTLNNWLATVTLGQAGMHATYYHKASDQLQVGVEFEASTRMQDTSASFGYQLDLPKANFLFKGSVNSNWIVGATLEKKLPPLPLTLSLCAFLNHRKNKFLCGFGLTIG

Target ORF information:

RefSeq Version	XM_006228420.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus translocase of outer mitochondrial membrane 40 (Tomm40), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006228420.3

ORF Insert Sequence:

ATGGGGAACG TGTTGGCTGC TAGCTCTCCG CCCGCAGGGC CACCGCCGCC TCCTACGCCG 
TCCCTCGTGG GGCTCCCGCC GCCGCCTCCT TCGCCGCCAG GCTTCACGCT GCCGCCACTT 
GGAGGTGGCC TGGGCACTGG GTCAAACGCT GGTCGCGGTT CGGAACGGAC TCCCGGGGCC 
GCGGCGAGCG GCGCTGCGGC GTCCTCGAAC GATGGGAACT GCGGCTGCCT GCCCAACCCG 
GGGACGTTCG AGGAGTGCCA CCGGAAGTGC AAGGAGCTGT TTCCAGTTCA GATGGAAGGT 
GTCAAACTTA CAGTCAACAA AGGGTTAAGC AATCGTTTCC AGGTGACCCA TACAGTAGCC 
CTCGGCACAA TTGGGGAGTC CAACTACCAC TTCGGGGTTA CATACGTGGG GACAAAACAG 
CTGAGTCCCA CAGAGGCGTT CCCCGTGCTG GTGGGTGACA TGGACAATAG TGGCAGCCTC 
AATGCACAGG TCATCCACCA GCTGAGCCCA GGCCTCAGGT CCAAGATGGC CATCCAGACC 
CAGCAGTCCA AGTTCGTGAA CTGGCAGGTG GATGGCGAGT ACCGTGGCTC CGACTTCACG 
GCTGCTGTCA CCCTGGGCAA CCCAGATGTC TTGGTGGGTT CAGGAATCCT CGTGGCTCAC 
TACCTCCAGA GCATCACACC GTGTCTGGCC CTAGGTGGCG AGCTCGTCTA CCACCGGCGG 
CCTGGAGAAG AGGGCACTGT CATGTCTCTA GCTGGGAAAT ACACACTGAA CAACTGGTTG 
GCTACAGTAA CGCTGGGTCA GGCAGGCATG CATGCGACGT ATTACCACAA AGCCAGTGAC 
CAGCTGCAGG TGGGTGTGGA GTTTGAGGCC AGCACCAGGA TGCAGGACAC CAGTGCCTCC 
TTTGGGTATC AGCTGGACCT GCCCAAGGCC AACTTCCTCT TCAAAGGCTC TGTGAACAGT 
AACTGGATCG TGGGTGCCAC GCTGGAGAAG AAGCTTCCGC CCTTGCCCCT GACACTGTCG 
CTCTGCGCCT TCCTGAACCA CCGCAAGAAT AAGTTCCTGT GTGGCTTTGG CCTCACCATC 
GGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Biogenesis of mitochondrial outer membrane proteins, problems and diseases.
Biological chemistry396(11)1199-213(2015 Nov)
Ellenrieder L,M?rtensson CU,Becker T

Association of
Biomedical reports3(4)491-498(2015 Jul)
Yamase Y,Horibe H,Ueyama C,Fujimaki T,Oguri M,Kato K,Arai M,Watanabe S,Yamada Y

Cooperation of protein machineries in mitochondrial protein sorting.
Biochimica et biophysica acta1853(5)1119-29(2015 May)
Wenz LS,Opali?ski ?,Wiedemann N,Becker T

Unlocking the presequence import pathway.
Trends in cell biology25(5)265-75(2015 May)
Schulz C,Schendzielorz A,Rehling P

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Tomm40 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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