gRNAs
The following Shprh gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Shprh cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa11205 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001107470.1 | |
| Accession Version | NM_001107470.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 5106bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-10-01 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | E3 ubiquitin-protein ligase SHPRH | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473994.1. On or before Oct 4, 2007 this sequence version replaced XM_218084.4, XM_001069964.1. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN02642688 [ECO:0000350] ##Evidence-Data-END## | |
1 | ATGAGTAGCC GAAGGAAACG TGCTCCCCCG ATGAAGGTGG ATGAAGAAAG GCAGCAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001100940.1 |
| CDS | 196..5301 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001107470.1 |
1 | ATGAGTAGCC GAAGGAAACG TGCTCCCCCG ATGAAGGTGG ATGAAGAAAG GCAGCAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa22006 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006227639.2 | |
| Accession Version | XM_006227639.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 5049bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | E3 ubiquitin-protein ligase SHPRH isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006227639.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGAGTAGCC GAAGGAAACG TGCTCCCCCG ATGAAGGTGG ATGAAGAAAG GCAGCAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006227701.1 |
| CDS | 237..5285 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006227639.2 |
1 | ATGAGTAGCC GAAGGAAACG TGCTCCCCCG ATGAAGGTGG ATGAAGAAAG GCAGCAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
DNA damage-specific deubiquitination regulates Rad18 functions to suppress mutagenesis. |
Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks. |
Human SHPRH suppresses genomic instability through proliferating cell nuclear antigen polyubiquitination. |
Human SHPRH is a ubiquitin ligase for Mms2-Ubc13-dependent polyubiquitylation of proliferating cell nuclear antigen. |
