The following Socs6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Socs6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa10405 | |
| Clone ID Related Accession (Same CDS sequence) | XM_017600943.1 , XM_017600942.1 , XM_006255033.3 , NM_001271149.1 | |
| Accession Version | NM_001271149.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1644bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-05-30 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | suppressor of cytokine signaling 6 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07032855.1. On or before Sep 5, 2012 this sequence version replaced XM_225667.6, XM_001063512.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: FQ102766.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGAAGAAAA TCAGTCTGAA GACCTTCAGG AAATCTTTCA ATCTGAGTAA AAGCAAAGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001258078.1 |
| CDS | 256..1899 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001271149.1 |
1 | ATGAAGAAAA TCAGTCTGAA GACCTTCAGG AAATCTTTCA ATCTGAGTAA AAGCAAAGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa10405 | |
| Clone ID Related Accession (Same CDS sequence) | XM_017600943.1 , XM_017600942.1 , XM_006255033.3 , NM_001271149.1 | |
| Accession Version | XM_017600943.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1644bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | suppressor of cytokine signaling 6 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005117.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGAAGAAAA TCAGTCTGAA GACCTTCAGG AAATCTTTCA ATCTGAGTAA AAGCAAAGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_017456432.1 |
| CDS | 786..2429 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_017600943.1 |
1 | ATGAAGAAAA TCAGTCTGAA GACCTTCAGG AAATCTTTCA ATCTGAGTAA AAGCAAAGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa10405 | |
| Clone ID Related Accession (Same CDS sequence) | XM_017600943.1 , XM_017600942.1 , XM_006255033.3 , NM_001271149.1 | |
| Accession Version | XM_017600942.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1644bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | suppressor of cytokine signaling 6 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005117.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGAAGAAAA TCAGTCTGAA GACCTTCAGG AAATCTTTCA ATCTGAGTAA AAGCAAAGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_017456431.1 |
| CDS | 330..1973 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_017600942.1 |
1 | ATGAAGAAAA TCAGTCTGAA GACCTTCAGG AAATCTTTCA ATCTGAGTAA AAGCAAAGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa10405 | |
| Clone ID Related Accession (Same CDS sequence) | XM_017600943.1 , XM_017600942.1 , XM_006255033.3 , NM_001271149.1 | |
| Accession Version | XM_006255033.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1644bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | suppressor of cytokine signaling 6 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005117.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006255033.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGAAGAAAA TCAGTCTGAA GACCTTCAGG AAATCTTTCA ATCTGAGTAA AAGCAAAGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006255095.1 |
| CDS | 621..2264 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006255033.3 |
1 | ATGAAGAAAA TCAGTCTGAA GACCTTCAGG AAATCTTTCA ATCTGAGTAA AAGCAAAGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Suppressor of cytokine signalling-6 promotes neurite outgrowth via JAK2/STAT5-mediated signalling pathway, involving negative feedback inhibition. |
SOCS-6 negatively regulates T cell activation through targeting p56lck to proteasomal degradation. |
Attenuation of leptin and insulin signaling by SOCS proteins. |
Inhibitors of cytokine signal transduction. |
SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation. |
